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  • 2015-2019  (55)
  • 1995-1999
  • 1970-1974
  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (55)
  • Oncology  (55)
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Language
Years
Year
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Publisher
Keywords
  • 1
    Online Resource
    Online Resource
    Glioma : Contemporary Diagnostic and Therapeutic Approaches (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789849547 , 9781789849530 , 9781838816551
    Language: Undetermined
    Pages: 1 Online-Ressource (258 p.)
    Keywords: Oncology
    Abstract: The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two
    Note: English
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  • 2
    Online Resource
    Online Resource
    Oncogenes and Carcinogenesis (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789851724 , 9781789851717 , 9781839620621
    Language: Undetermined
    Pages: 1 Online-Ressource (106 p.)
    Keywords: Oncology
    Abstract: Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis
    Note: English
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  • 3
    Online Resource
    Online Resource
    Primary Intracranial Tumors (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789854060 , 9781789854053 , 9781839620805
    Language: Undetermined
    Pages: 1 Online-Ressource (140 p.)
    Keywords: Oncology
    Abstract: This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone
    Note: English
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  • 4
    Online Resource
    Online Resource
    Knowledges on Thyroid Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239843 , 9781789239836 , 9781838818913
    Language: Undetermined
    Pages: 1 Online-Ressource (116 p.)
    Keywords: Oncology
    Abstract: Thyroid cancer is being increasingly diagnosed nowadays. This situation has attracted the attention of scientists and physicians alike and new applications in diagnosis and treatment are being developed and used. There are many cases associated with thyroid cancer and in this book, thyroid cancer is examined in various aspects
    Note: English
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  • 5
    Online Resource
    Online Resource
    Recent Developments in Myelodysplastic Syndromes (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789854787 , 9781789854770 , 9781839620409
    Language: Undetermined
    Pages: 1 Online-Ressource (120 p.)
    Keywords: Oncology
    Abstract: This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit
    Note: English
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  • 6
    Online Resource
    Online Resource
    Update on Multiple Myeloma (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789852189 , 9781789852172 , 9781839620287
    Language: Undetermined
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Oncology
    Abstract: This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries
    Note: English
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  • 7
    Online Resource
    Online Resource
    Advances in the Molecular Understanding of Colorectal Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789850604 , 9781789850598 , 9781839620041
    Language: Undetermined
    Pages: 1 Online-Ressource (172 p.)
    Keywords: Oncology
    Abstract: An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer
    Note: English
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  • 8
    Online Resource
    Online Resource
    Peripheral T-cell Lymphomas (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838812263 , 9781838812256 , 9781838812270
    Language: Undetermined
    Pages: 1 Online-Ressource (132 p.)
    Keywords: Oncology
    Abstract: In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas
    Note: English
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  • 9
    Online Resource
    Online Resource
    Bile Duct Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789238761 , 9781789238754 , 9781839622151
    Language: Undetermined
    Pages: 1 Online-Ressource (112 p.)
    Keywords: Oncology
    Abstract: Cholangiocarcinoma is a type of malignant tumor that affects the biliary system. It can arise anywhere in the bile ducts, manifesting itself as obstructive jaundice. It has an annual incidence of 1-2 cases per 100,000 people. One variety of the disease, the Klatskin tumor, occurs in the hepatic hilum and is characterized by poor prognosis. Generally, cholangiocarcinomas are slow-growing tumors with late metastases. Localized tumors are treated surgically, but intervention is discouraged when they are extensive. The disease affects both sexes, but most cases occur in patients aged over 60 years. Primary sclerosing cholangitis, chronic biliary infection, and choledochal cysts are associated with an increased risk of cholangiocarcinoma
    Note: English
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  • 10
    Online Resource
    Online Resource
    Prostatectomy (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838806859 , 9781838806842 , 9781838806866
    Language: Undetermined
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Oncology
    Abstract: The prostate gland is one of the male organs that have changed over the years. Those changes lead to a disruption of the quality of life and risk of prostate cancer in men over 50 years of age. In the era of prostate-specific antigen it is possible to overcome prostate cancer through early diagnosis. This made it possible to treat the diagnosis of prostate cancer and prevent the development of prostate cancer disease in the patient. In addition, early diagnosis has led to advances in the technological development of the basic surgical technique - prostatectomy. This book contains the efforts of a number of doctors and scientists interested in the prostate gland from different countries around the world. Some of these studies are likely to pose new challenges and trends in the diagnosis of the prostate gland and basic surgical technique
    Note: English
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  • 11
    Online Resource
    Online Resource
    Cancer Survivorship (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789849073 , 9781789849066 , 9781838817893
    Language: Undetermined
    Pages: 1 Online-Ressource (140 p.)
    Keywords: Oncology
    Abstract: This book is a marvelous compendium of eight articles that cover a wide range of topics, including breast cancer: management and survivorship, rectal cancer intersphincteric resection, head and neck cancer diagnosis and radiotherapy, synthetic peptides as antitumor agents, and recent advances in thyroid cancer. It has been a wonderful opportunity to co-edit this special edition. We are greatly appreciative of the work of all the contributors to the book, who brought with them tremendous diversity of perspectives and fields truly reflective of the complexity of the topic and who, through coming together in this project, serve as a nidus of the multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies that have provided the information that has advanced the field so greatly in recent years
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  • 12
    Online Resource
    Online Resource
    Gastric Cancer : An Update (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789857467 , 9781789857450 , 9781839620959
    Language: Undetermined
    Pages: 1 Online-Ressource (102 p.)
    Keywords: Oncology
    Abstract: This book, Gastric Cancer - An Update, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of gastric cancer. The book is comprised of single chapters authored by various researchers and it is edited by experts active in this field of study. All chapters are complete in itself but united under a common research topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on gastric cancer, and opening new possible research paths for further novel developments
    Note: English
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  • 13
    Online Resource
    Online Resource
    Current Trends in Cancer Management (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838800062 , 9781838800055 , 9781839622076
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Oncology
    Abstract: The field of cancer diagnosis, prognosis, and treatment is constantly advancing. From novel biomarkers to cutting-edge imaging solutions, changing chemotherapy protocols and novel immune-targeting agents, medical teams develop and test new ways to manage this ever-growing threat to the modern age. Imaging has been a reliable method for initial diagnosis and later surveillance of premalignant and cancerous lesions of the digestive tract. This book project aims to characterize the main diagnostic procedures and novel medical and surgical treatments, as well as provide an updated view on current guidelines, premalignant lesions management, and minimally invasive curative techniques
    Note: English
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  • 14
    Online Resource
    Online Resource
    Tyrosine Kinases as Druggable Targets in Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789848090 , 9781789848083 , 9781839622199
    Language: English
    Pages: 1 Online-Ressource (134 p.)
    Keywords: Oncology
    Abstract: Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL in chronic myeloid leukemia (CML), has revolutionized disease management. In this book, we examine a few aspects of PTKs and cancer, considering efficacy, predictive markers to therapeutic response, limitations, and future directions in TKI treatment. In this rapidly evolving field, overcoming therapeutic resistance is most challenging, and multi-targeting directs the next-generation TKIs and combination therapy as ongoing strategies in cancer treatment
    Note: English
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  • 15
    Online Resource
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    Multidisciplinary Approach for Colorectal Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789844009 , 9781789843996 , 9781839680434
    Language: English
    Pages: 1 Online-Ressource (106 p.)
    Keywords: Oncology
    Abstract: A multidisciplinary understanding of the various processes leading to colorectal cancer progression is important for creating promising methods of therapy. Therefore it is necessary to scrutinize the progression of cancer and the therapeutic process through various academic theories. This book examines colorectal cancer - its prevention, pathogenesis, and treatment - through a multidisciplinary lens in an effort to advance understanding of the disease and improve therapeutic efficacy
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  • 16
    Online Resource
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    Cancer Immunotherapy and Biological Cancer Treatments (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789848632 , 9781789848625 , 9781789843668
    Language: English
    Pages: 1 Online-Ressource (112 p.)
    Keywords: Oncology
    Abstract: In recent years, biological cancer therapies, including immunotherapy, have moved from the bench to mainstream medical treatments of several types of cancer. The success of these treatments relies on innovative approaches to specifically interfere with molecular targets that are involved in the growth, progression, and spread of malignant cells, or to bypass the tumor evasion of the immune system utilizing the latest advances in cancer vaccine development, formulation, and delivery. This book presents an up-to-date overview of novel cancer biological and immunotherapeutic approaches, including cancer vaccines, mimetic vaccines, monoclonal antibodies, adoptive T-cell transfer, chimeric antigen receptor T- cells, tumor infiltrating lymphocytes, dendritic cells, natural killer cells, immune checkpoint inhibitors, laser ablation, and immune stimulating interstitial laser thermotherapy
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  • 17
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    Advances in Hematologic Malignancies (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239423 , 9781789239416 , 9781839626579
    Language: English
    Pages: 1 Online-Ressource (176 p.)
    Keywords: Oncology
    Abstract: The book Advances in Hematologic Malignancies presents new knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic, and genomic changes that have influenced the current outlook toward hematological malignancies. This book provides a unique, practical, and concise guide that is focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. Advances in Hematologic Malignancies is designed and organized as an essential reference source for the hematologist, hematologic oncologist, hematopathologist, and trainee
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  • 18
    Online Resource
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    Gene Expression Profiling in Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838801762 , 9781838801755 , 9781789853834
    Language: English
    Pages: 1 Online-Ressource (78 p.)
    Keywords: Oncology
    Abstract: The contribution of modern-day genetics in designing efficient gene expression profiles for cancer is immense. The progress of technology and science in recent years provides the opportunity for discovery and application of new techniques for treating various diseases that affect humanity. Methods for finding and analyzing the profile of gene expression of infected cells give scientists the ability to develop more targeted and effective treatments, especially for diseases such as cancer. The development of gene expression profiling is one of the most important achievements in cancer genetics in our time. It is essentially the driving force behind personalized and precision medicine. This book highlights recent developments, applications, and breakthroughs in the field of gene expression profiling in cancer
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  • 19
    Online Resource
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    Germ Line Mutations Associated Leukemia (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789840247 , 9781789840230 , 9781789844030
    Language: English
    Pages: 1 Online-Ressource (94 p.)
    Keywords: Oncology
    Abstract: In the current practice of modern medicine, the treatment of infectious and nutritional disorders is well established. In contrast, currently genetic disorders/diseases and cancer constitute a substantial load in the clinic. The care of genetic-based diseases and cancer has become a major task in medical practices worldwide and it is unprecedented. It will be rare for any family to be entirely free of genetic disease, therefore genetic diseases impose a huge burden upon individuals, families, and societies. Modern medicine is at the crossroads in the new genomic era with the development of more and more modern technologies. Remarkable advances have been well achieved in defining and classifying these genetic-associated diseases. The identification of the genetic landscape of germ line mutations-associated leukemia caused by either inherited gene mutations or syndromes has led to a deep understanding of leukemogenesis, recognition of clinical diagnosis, and translation into clinical practice in its specific management strategies
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  • 20
    Online Resource
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    Prevention, Detection and Management of Oral Cancer (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789845037 , 9781789845020 , 9781789846041
    Language: English
    Pages: 1 Online-Ressource (114 p.)
    Keywords: Oncology
    Abstract: Up to 70% of oral cancers are preceded by premalignant oral lesions, such as persistent red or white patches in the mouth. Survival rates for oral cancer can be improved through early detection. It is therefore essential that oral health professionals such as dentists, dental hygienists, dental therapists, and oral health therapists understand the importance of conducting a thorough oral screening examination for malignant and potentially malignant lesions as part of their routine clinical assessments, even in younger populations considered at lower risk for oral cancer. Key features of the book include: laser treatment techniques ,human genome sequencing, early detection and multidisciplinary approach ,management strategies and mechanisms of proliferation and energy metabolism in oral cancer
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  • 21
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    Neoplasm (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789237788 , 9781789237771 , 9781838813932
    Language: Undetermined
    Pages: 1 Online-Ressource (254 p.)
    Keywords: Oncology
    Abstract: Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists
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  • 22
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    Ovarian Cancer : From Pathogenesis to Treatment (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789843347 , 9781789843330 , 9781838812669
    Language: Undetermined
    Pages: 1 Online-Ressource (364 p.)
    Keywords: Oncology
    Abstract: Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management
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  • 23
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    Cancer Management and Therapy (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789232998 , 9781789232981 , 9781838813017
    Language: Undetermined
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Oncology
    Abstract: There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters
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  • 24
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    Liver Cancer (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789844498 , 9781789844481 , 9781838817541
    Language: Undetermined
    Pages: 1 Online-Ressource (186 p.)
    Keywords: Oncology
    Abstract: This book offers remarkable coverage of liver cancer from etiology to prevention and treatment. It provides an updated and new vision of this major cancer that continues to affect hundreds of thousands of people and remains one of the leading causes of cancer deaths around the world. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. The book includes detailed and updated descriptions of the main causes of liver cancer and also the prevention and treatment of this disease. This book is a relevant source of knowledge, very useful for researchers, medical doctors, medical residents, students, healthcare providers, public health decision makers, and all individuals interested in the prevention of this disease
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  • 25
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    Human Skin Cancers : Pathways, Mechanisms, Targets and Treatments (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789230956 , 9781789230949 , 9781838812782
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Oncology
    Abstract: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas
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  • 26
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    Esophageal Cancer and Beyond (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789844139 , 9781789844122 , 9781838817602
    Language: Undetermined
    Pages: 1 Online-Ressource (92 p.)
    Keywords: Oncology
    Abstract: Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease
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  • 27
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    Myeloid Leukemia (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789231038 , 9781789231021 , 9781838813666
    Language: Undetermined
    Pages: 1 Online-Ressource (190 p.)
    Keywords: Oncology
    Abstract: This book offers a remarkable coverage of myeloid leukemia from diagnosis to treatment. It provides an updated and new vision of this multifaceted disease, regrouping a variety of myeloid disorders. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. This book is a relevant source of knowledge, very useful for researchers, medical doctors, nurses, students and individuals interested in this complex disease
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  • 28
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    Cancer Causing Substances (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789231410 , 9781789231403 , 9781838812959
    Language: Undetermined
    Pages: 1 Online-Ressource (80 p.)
    Keywords: Oncology
    Abstract: Cancer risk factors include exposure to certain substances, which may contribute to the development of cancer. However, substances can have different levels of cancer-causing potential, and the risk of developing cancer is dependent on several factors, including individual genetic background and the amount and duration of the exposure. This book focuses on various cancer risk factors, covering numerous known, probable, and possible carcinogens; their role in carcinogenesis; mechanisms of carcinogenicity; and methods for detecting carcinogens. And due to the growing concerns over the effects that substances and environmental exposures can have on human health, the chapters also emphasize on the vital need for further topic-related research as well as development and implementation of beneficial approaches
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  • 29
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    Cancer Metastasis (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789846331 , 9781789846324 , 9781838818012
    Language: Undetermined
    Pages: 1 Online-Ressource (152 p.)
    Keywords: Oncology
    Abstract: Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis
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  • 30
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    Thalassemia and Other Hemolytic Anemias (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789233674 , 9781789233667 , 9781838813406
    Language: Undetermined
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Oncology
    Abstract: Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high
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  • 31
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    Cervical Cancer : Screening, Treatment and Prevention - Universal Protocols for Ultimate Control (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789231458 , 9781789231441 , 9781838814670
    Language: Undetermined
    Pages: 1 Online-Ressource (130 p.)
    Keywords: Oncology
    Abstract: This book entitled Cervical Cancer - Screening, Treatment and Prevention Universal Protocols for Ultimate Control is the fourth successful endeavor of the Editor with InTech publisher. The four books serve as four pillars in cervical cancer control, globally. This book is unique and sensational. Public health "topics" are assuming a status of "phenomenon," through deliberations and research. Screening is riddled with global limitations of availability, affordability, acceptability, and accessibility. The treatment of precancers has questionable efficiency. Prevention is costly with the inclusion of HPV vaccine. This book helps to find the solutions. The authors, editor, and InTech publisher wish the readers a pleasant and purposeful reading. This book is a "readers' feast," "receivers' choice," and "respondents' delight." Enjoy and treasure the international facts and flavors
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  • 32
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    Advances in Pancreatic Cancer (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789236415 , 9781789236408 , 9781838816834
    Language: Undetermined
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Oncology
    Abstract: Pancreatic cancer is a growing source of cancer-related death and has poor survival rates, which have not improved in the last few decades. Its high-mortality rate is attributed to pancreatic cancer biology, difficulty in early diagnosis, and lack of standardized international guidelines in assessing the pancreatic masses. This book aims to provide an update in the current state of play in pancreatic cancer diagnosis and to evaluate the benefits and limitations of the available diagnostic technology and therapy. The main modalities for diagnosis are imaging with HCT, MRI, USE, and PET. Some chapters review the improvements in the techniques used. Timely and accurate diagnosis of pancreatic cancer can lead to improve in the current poor outcome of this disease
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  • 33
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    Hepatocellular Carcinoma : Advances in Diagnosis and Treatment (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789842746 , 9781789842739 , 9781838814151
    Language: Undetermined
    Pages: 1 Online-Ressource (200 p.)
    Keywords: Oncology
    Abstract: Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed
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  • 34
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    Lung Cancer : Strategies for Diagnosis and Treatment (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789843507 , 9781789843491 , 9781838816391
    Language: Undetermined
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Oncology
    Abstract: Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer
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  • 35
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    Hematology : Latest Research and Clinical Advances (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789233513 , 9781789233506 , 9781838814717
    Language: Undetermined
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Oncology
    Abstract: Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of blood diseases. This has in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options in hematology requires a frequent update of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research in hematological diseases with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients, as well as on some molecular and pathogenetic mechanisms and the respective translation into novel therapies
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  • 36
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    Brain Tumors : An Update (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789235579 , 9781789235562 , 9781838815097
    Language: Undetermined
    Pages: 1 Online-Ressource (248 p.)
    Keywords: Oncology
    Abstract: We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book "Brain Tumor - An Update" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book
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  • 37
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    Cancer Prognosis (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789847758 , 9781789847741 , 9781838817220
    Language: English
    Pages: 1 Online-Ressource (76 p.)
    Keywords: Oncology
    Abstract: Cancer is a DNA disease in which the early stage is represented by the inactivation of suppressor genes and activation of oncogenes, which result in transformed cells that grow out of biological control. Tumor progression is locally favored by mitogenic effects of hormones, or growth factors that stimulate the tumor's growth, or by inducing angiogenesis. The book contains chapters written by experts in the topic, and exhibits current developments in the methodology of cell and molecular biology, which have deeply advanced the understanding of cancer's prevention and prognosis. We hope that it will be helpful for physicians, researchers, and students in life sciences, and will stimulate discussion and research for new therapeutic approaches against cancer
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  • 38
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    Head and Neck Cancer : Diagnosis and Management of (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535134961 , 9789535134954 , 9789535146599
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Oncology
    Abstract: This book includes useful and recent information to the readers regarding the following topics: Signs and symptoms and etiology and risk factors of head and neck cancer, Epidemiology and the role of microRNAs in nasopharyngeal carcinoma and oral carcinogenesis, History, classifications, and managements of salivary gland cancer, Considerations, classifications, and managements of thyroid gland cancer, Updates in the diagnosis and management of medullary thyroid carcinoma, Interventional techniques used for the relief of head and neck cancer pain, Oral side effects of head and neck irradiation, Health-related quality of life in maxillectomy patients rehabilitated with obturator prostheses
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  • 39
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    Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535133360 , 9789535133353 , 9789535147459
    Language: Undetermined
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Oncology
    Abstract: The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases
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  • 40
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    Neuroblastoma : Current State and Recent Updates (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535135845 , 9789535135838 , 9789535146193
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Oncology
    Abstract: Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma
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  • 41
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    Updates in Liver Cancer (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535130642 , 9789535130635 , 9789535148852
    Language: Undetermined
    Pages: 1 Online-Ressource (222 p.)
    Keywords: Oncology
    Abstract: Liver cancers result in considerable amount of financial and social burden. On the other hand, researches and clinical studies related to liver cancers continue to advance at a rapid pace. The chapters in this book provide state-of-the-art reviews on the current knowledge and advances in research and management of liver cancers. It includes the most recent advances in that field, particularly, hepatocarcinogenesis and the potential role of intestinal microbiota, nonalcoholic steatohepatitis, cancer stem cells, aldehyde dehydrogenase-1, and hepatitis B virus. This book also discusses the methods of diagnosis of HCC, the minimally invasive therapies for liver cancers, living donor liver transplantation for HCC, surgical management of liver metastases from colorectal cancers, and assessment and optimization for the future liver remnant
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  • 42
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    Tumor Metastasis (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535126317 , 9789535126300 , 9789535141815
    Language: Undetermined
    Pages: 1 Online-Ressource (266 p.)
    Keywords: Oncology
    Abstract: Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis
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  • 43
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    Free Radicals and Diseases (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535127475 , 9789535127468 , 9789535141655
    Language: Undetermined
    Pages: 1 Online-Ressource (386 p.)
    Keywords: Oncology
    Abstract: The current volume entitled, "Free Radicals and Diseases" integrates knowledge in free radical-associated diseases from the basic level to the advanced level, and from the bench side to bed side. The chapters in this book provide an extensive overview of the topic, including free radical formations and clinical interventions
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  • 44
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    Human Skin Cancer, Potential Biomarkers and Therapeutic Targets (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535127116 , 9789535127109 , 9789535173175
    Language: Undetermined
    Pages: 1 Online-Ressource (150 p.)
    Keywords: Oncology
    Abstract: Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern
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  • 45
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    Human Papillomavirus : Research in a Global Perspective (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535124405 , 9789535124399 , 9789535141976
    Language: Undetermined
    Pages: 1 Online-Ressource (318 p.)
    Keywords: Oncology
    Abstract: This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The authors, editor, and Intech publishers, together, are pleased to provide the readers a precious blend of scientific excellence and social relevance, for health empowerment, globally. We wish the readers great success, savoring science and sociology together
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  • 46
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    New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535122531 , 9789535143826 , 9789535172758
    Language: English
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Oncology
    Abstract: Written by an international team of experts in the field of human carcinogenesis, this book discusses recent advances in cancer research, which include the following topics: basic molecular and cellular mechanisms behind cancer growth, new approaches in cancer therapy, and cancer diagnostic. The book serves as a useful source of reference for cancer biologists, medical doctors, and clinical researchers in the fields of cancer diagnosis, prevention, and treatment
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  • 47
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    Neurooncology : Newer Developments (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535124269 , 9789535124252 , 9789535172857
    Language: English
    Pages: 1 Online-Ressource (488 p.)
    Keywords: Oncology
    Abstract: The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management
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  • 48
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    Role of Biomarkers in Medicine (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535125068 , 9789535125051 , 9789535154433
    Language: English
    Pages: 1 Online-Ressource (260 p.)
    Keywords: Oncology
    Abstract: The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management
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  • 49
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    Thyroid Cancer : Advances in Diagnosis and Therapy (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535125891 , 9789535125884 , 9789535172987
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Oncology
    Abstract: Thyroid cancer is the eighth most common type of cancer and is most frequently diagnosed among people aged 45-54. Nearly three out of four cases are found in women, while about 2% of thyroid cancers occur in children and teenagers. This book is for medical doctors with experience in the field of thyroid cancer. It comprises different subjects, especially the advances in the diagnosis of thyroid cancer with PET imaging and elastography, as well as the new therapeutic approaches with tyrosine kinase inhibitors
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  • 50
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    Drug Discovery and Development : From Molecules to Medicine (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535121282 , 9789535142225
    Language: Undetermined
    Pages: 1 Online-Ressource (330 p.)
    Keywords: Oncology
    Abstract: It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology
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  • 51
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    Contemporary Issues in Head and Neck Cancer Management (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535121350 , 9789535172468
    Language: English
    Pages: 1 Online-Ressource (180 p.)
    Keywords: Oncology
    Abstract: While the management of head and neck cancer has evolved over the last few decades, there are still several challenges and unanswered questions that need solutions. This book is a small compilation of some topical aspects regarding head and neck cancer treatment, including the etiology of HPV-positive oropharyngeal cancers and risk factors in the young population, the challenge of surgical margin definition and the perennial problem of systemic treatment due to distant metastases. Radiobiological aspects are also covered through the Rs of radiotherapy, with a couple of chapters being dedicated to radioresistance and tumour microenvironment. Contemporary Issues in Head and Neck Cancer Management comes as an addition to the existing literature that aims to tackle this radiobiologically challenging tumour
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  • 52
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    Leukemias : Updates and New Insights (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535122029 , 9789535172635
    Language: English
    Pages: 1 Online-Ressource (364 p.)
    Keywords: Oncology
    Abstract: Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of leukemias. This in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways in leukemic cells. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options of leukemias requires frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research of acute and chronic leukemias with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients with leukemias; on specific clinical scenarios such as pregnancy or age; as well as on some molecular and pathogenetic mechanisms and their respective translation into novel therapies
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  • 53
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    Updates on Cancer Treatment (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535121947 , 9789535172598
    Language: English
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Oncology
    Abstract: In spite of advances in the cancer research field, cancer treatment still challenges researchers and clinicians, as proven by the still impressive and increasing number of worldwide cancer-related deaths. Updates on Cancer Treatment is an attempt to integrate into a book volume various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field
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  • 54
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    Melanoma : Current Clinical Management and Future Therapeutics (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535120360 , 9789535172376
    Language: English
    Pages: 1 Online-Ressource (412 p.)
    Keywords: Oncology
    Abstract: Melanoma - Current Clinical Management and Future Therapeutics serves as an advanced course in melanoma or an addendum to further polish expertise. Sections of the book include a thorough introduction on epidemiology and disease, the current surgical management of melanoma and lymph node dissection, immunotherapy along with drug toxicities and emerging research topics, like RAGE and autotaxin, that have potential therapeutic applications. The chapters in this book explore the most common subtype of melanoma, cutaneous disease, as well as a rare form, acral lentiginous melanoma and even canine tumors. Experts from around the globe contributed chapters, most of which have visual illustrations to depict aspects of disease management and therapy, allowing readers to grasp the advanced concepts presented
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 55
    Online Resource
    Online Resource
    Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535120315 , 9789535172352
    Language: English
    Pages: 1 Online-Ressource (434 p.)
    Keywords: Oncology
    Abstract: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided
    Note: English
    URL: kostenfrei
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    MPI Ethno. Forsch.
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