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  • 2010-2014  (45)
  • 1995-1999  (38)
  • Organisation for Economic Co-operation and Development  (83)
  • Safari, an O’Reilly Media Company
  • Environment  (83)
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  • 1
    Online Resource
    Online Resource
    Mortality Risk Valuation in Environment, Health and Transport Policies (2012)
    Paris : OECD Publishing
    Details
    ISBN: 9789264130807
    Language: English
    Pages: Online-Ressource (140 p.)
    Keywords: Environment ; Social Issues/Migration/Health ; Transport
    Abstract: The book presents a major meta-analysis of 'value of a statistical life' (VSL) estimates derived from surveys where people around the world have been asked about their willingness to pay for small reduction in mortality risks. The analysis seeks to explain the differences in the estimates, for example across countries. Differences in incomes and the magintude of the risk reduction people have been asked to value were found to be the factors having the strongest impact on VSL, but a number of other policy-relevant factors are also important. Based on the meta-analysis, and a broad review of the literature, the book also presents clear advice on how VSL values best can be used in assessments of environmental, health and transport policies, such as in cost-benefit analyses. Using explicit VSL estimates to quantify the benefits to society of fatality risk reductions can play an important role in the development of more cost-effective public policies.
    DOI: 10.1787/9789264130807-en
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  • 2
    Online Resource
    Online Resource
    Strategic Environmental Assessment in Development Practice : A Review of Recent Experience (2012)
    Paris : OECD Publishing
    Details
    ISBN: 9789264166745
    Language: English
    Pages: Online-Ressource (124 p.)
    Parallel Title: Erscheint auch als Strategic environmental assessment in development practice
    Keywords: Umweltverträglichkeit ; Entwicklungshilfe ; Entwicklungsländer ; Environment ; Development ; Entwicklungsländer ; Entwicklungshilfe ; Umweltverträglichkeit
    Abstract: The principles of sustainable development play an integral role in making development assistance work at the level of policies, plans and programmes. In response to the Paris Declaration call to “… develop and apply common approaches for ‘Strategic Environmental Assessment’ at sector and national levels” among donors and partners, the Guidance on Applying Strategic Environmental Assessment was endorsed in 2006 by members of the OECD Development Assistance Committee, representatives of developing countries receiving aid, the United Nations Development Programme, the United Nations Environment Programme, the World Bank and many other agencies. Since then, a growing number of countries at all levels of development have legislation or regulations prescribing the application of Strategic Environmental Assessment (SEA)  and many more are introducing it as part of their policy tools. This is creating unique opportunities for better policy making and planning by incorporating environmental considerations into high-level decision-making and opening new mechanisms to build consensus on development priorities within governments themselves and between governments and societies. Many development co-operation agencies and their partners are already making good progress in applying SEA. This publication presents the nine most interesting case studies of SEA in progress, selected from a total 100. These nine cases highlight that SEA can:• Safeguard environmental assets for sustainable poverty reduction and development;• Build public engagement in decision making;• Prevent costly mistakes by alerting decision-makers to potentially unsustainable development options at an early stage in the decision-making process;• Speed up implementation of projects and programmes;• Facilitate co-operation around shared environmental resources and contribute to conflict prevention.
    DOI: 10.1787/9789264166745-en
    URL: Volltext
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  • 3
    Online Resource
    Online Resource
    OECD Environmental Performance Reviews: Slovak Republic 2011 : (Slovak version) (2011)
    Bratislava : Ministry of Environment, Slovak Republic
    Details
    ISBN: 9788088833567
    Language: Slovak
    Pages: Online-Ressource (186 p.) , ill.
    Parallel Title: Parallelausg. OECD Environmental Performance Reviews; Slovak Republic 2011
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; République slovaque 2011
    Parallel Title: Parallelausg. OECD Environmental Performance Reviews: Slovak Republic 2011
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : République slovaque 2011
    Keywords: Environment ; Slovak Republic
    DOI: 10.1787/9788088833567-sk
    URL: Volltext
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  • 4
    Online Resource
    Online Resource
    OECD Environmental Performance Reviews: Norway 2011 (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264098473
    Language: English
    Pages: Online-Ressource (204 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environmentaux de l'OCDE; Norvège 2011
    Parallel Title: Parallelausg. Examens environmentaux de l'OCDE: Norvège 2011
    Keywords: Environment ; Norway
    Abstract: This report presents the third OECD review of Norway’s environmental policy performance. Previous reviews were published in 2001 and 1993. Topics covered in this report include greening growth, implementation of environmental policies, international cooperation, climate change, waste management and the 3Rs (reduce, reuse, recycle), and nature and biodiversity.
    DOI: 10.1787/9789264098473-en
    URL: Volltext
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  • 5
    Online Resource
    Online Resource
    Test No. 235: Chironomus sp., Acute Immobilisation Test (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264122383
    Language: English
    Pages: Online-Ressource (17 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 235 ; Chironomus sp., essai d'immobilisation immédiate
    Parallel Title: Parallelausg. Essai n 235 : Chironomus sp., essai d'immobilisation immédiate
    Keywords: Environment
    Abstract: This Test Guideline describes an acute immobilisation assay on chronomids and is designed to complement existing Test Guidelines for chironomid chronic toxicity assays (TG 218, 219 and 233). The test method is based on TG 202: Daphnia sp. Acute Immobilisation Test. First instar Chironomus sp. larvae are exposed to a range of concentrations of the test substance in water-only vessels for a period of 48 hours. C. riparius is the preferred species but C. dilutus or C. yoshimatsui may also be used for the test. At least 20 larvae, preferably divided into four groups of five larvae each, should be used for each test concentration and for controls. In the definitive test, at least five test concentrations should be used, with a dilution water control and solvent control (if appropriate). Immobilisation is recorded at 24 and 48 hours, and if data allow, the EC50 is calculated at 24 and 48 hours. A limit test with a single concentration may also be performed at 100 mg/L of test substance or up to the practical limit of solubility (whichever is lowest) in order to demonstrate that the EC50 is greater than this concentration.
    DOI: 10.1787/9789264122383-en
    URL: Volltext
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  • 6
    Online Resource
    Online Resource
    Paying for Biodiversity : Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version) (2011)
    Vienna : WWF Danube-Carpathian Programme
    Details
    ISBN: 9789264124974
    Language: Romanian
    Pages: Online-Ressource (201 p.)
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services
    Parallel Title: Parallelausg. Payer pour la biodiversité ; Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services
    Parallel Title: Parallelausg. Payer pour la biodiversité : Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Keywords: Environment
    DOI: 10.1787/9789264124974-ro
    URL: Volltext
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  • 7
    Online Resource
    Online Resource
    Test No. 234: Fish Sexual Development Test (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264122369
    Language: English
    Pages: Online-Ressource (44 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 234 ; Essai de développement sexuel des poissons
    Parallel Title: Parallelausg. Essai n 234 : Essai de développement sexuel des poissons
    Keywords: Environment
    Abstract: This Test Guideline describes an assay that assesses early life-stage effects and potential adverse consequences of putative endocrine disrupting chemicals (e.g. oestrogens, androgens and steroidogenesis inhibitors) on fish sexual development. In the test, fish are exposed, from newly fertilized egg until the completion of sexual differentiation at about 60 days post hatch, to at least three concentrations of the test substance dissolved in water. In each treatment level and control(s) group(s), a minimum of four replicates is recommended. At termination of the test, two core endpoints are measured in each fish: vitellogenin concentration from head and tail or from blood sampling, and proportion of males, females, intersex and undifferentiated fish through gonadal histology. In fish species possessing a genetic sex marker, the genetic sex is identified to determine sex reversal in individual fish. The combination of the two core endocrine endpoints, vitellogenin concentration and phenotypic (and possibly genotypic) sex ratio, enable the test to indicate the mode of action of the test chemical.
    DOI: 10.1787/9789264122369-en
    URL: Volltext
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  • 8
    Online Resource
    Online Resource
    OECD Environmental Performance Reviews: Portugal 2011 (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264097896
    Language: English
    Pages: Online-Ressource (184 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Portugal 2011
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Portugal 2011
    Keywords: Environment ; Portugal
    Abstract: This report presents the OECD review of Portugal’s environmental policy performance for 2011. It finds that environmental policies have been consolidated and strengthened since the last review in 2001, but that meeting the post-Kyoto targets for reducing greenhouse gas emissions will be challenging. With energy and climate policies being closely related, the report points out that with less than 50% of hydro capacity currently being exploited, there is potential for further development in that area. It also describes the challenges regarding coastal zone and marine management. Topics covered in the report include greening growth, implementation of environmental policies , international co-operation , climate change, waste management and the 3Rs (reduce, reuse, recycle), and nature and biodiversity. Further information about the Environmental Performance Review programme is available on line via www.oecd.org/env/countryreviews.
    DOI: 10.1787/9789264097896-en
    URL: Volltext
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  • 9
    Online Resource
    Online Resource
    Test No. 456: H295R Steroidogenesis Assay (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264122642
    Language: English
    Pages: Online-Ressource (21 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 456 ; Essai de stéroi͏̈dogenèse H295R
    Parallel Title: Parallelausg. Essai n 456 : Essai de stéroi͏̈dogenèse H295R
    Keywords: Environment
    Abstract: This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that encode for all the key enzymes for steroidogenesis. After an acclimation period of 24 h in multi-well plates, cells are exposed for 48 h to seven concentrations of the test chemical in at least triplicate. Solvent and a known inhibitor and inducer of hormone production are run at a fixed concentration as negative and positive controls. At the end of the exposure period, cell viability in each well is analyzed. Concentrations of hormones in the medium can be measured using a variety of methods including commercially available hormone measurement kits and/or instrumental techniques such as liquid chromatography-mass spectrometry. Data are expressed as fold change relative to the solvent control and the Lowest-Observed-Effect-Concentration. If the assay is negative, the highest concentration tested is reported as the No-Observed-Effect-Concentration.
    DOI: 10.1787/9789264122642-en
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  • 10
    Online Resource
    Online Resource
    Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento : Guia para o Desenvolvimento de Políticas (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264110618
    Language: Portuguese
    Pages: Online-Ressource (205 p.) , ill.
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation; Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement ; Document d'orientation
    Parallel Title: Parallelausg. Integración de la Adaptación en la Cooperación para el Desarrollo ; Guía sobre Políticas
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation: Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement : Document d'orientation
    Parallel Title: Parallelausg. Integración de la Adaptación en la Cooperación para el Desarrollo : Guía sobre Políticas
    Keywords: Environment ; Development
    Abstract: As alterações climáticas são uma ameaça séria e a longo prazo que pode afetar todo o globo. Os seus impactes negativos atingirão as pessoas pobres e os países pobres de forma desproporcional e comprometerão a persecução dos seus objetivos de desenvolvimento. Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento fornece informação essencial e aconselha o modo de facilitação a integração da adaptação nos processos de desenvolvimento. Os objetivos deste guia para o desenvolvimento de políticas são: i) promover o entendimento das implicações das alterações climáticas na prática do desenvolvimento e a necessidade associada de integrar a adaptação ao clima nas agências de cooperação para o desenvolvimento e nos países parceiros; ii) identificar abordagens apropriadas para integrar a adaptação às alterações climáticas nas políticas de desenvolvimento aos níveis nacional, setorial e de projeto e nos contextos urbanos e rurais; e iii) identificar meios práticos para os doadores apoiarem os países em desenvolvimento parceiros nos seus esforços para reduzir a sua vulnerabilidade à variabilidade e alterações climáticas. Enquanto os esforços para integrar a adaptação aos às alterações climáticas serão conduzidos pelos países em desenvolvimento parceiros, os doadores internacionais têm um papel crítico a desempenhar no apoio a tais esforços. Este guia para o desenvolvimento de políticas é especialmente formatado para os agentes de definição de políticas e para as agências de cooperação e suas contrapartes nos governos dos países em desenvolvimento, bem como para as partes interessadas não governamentais.
    DOI: 10.1787/9789264110618-pt
    URL: Volltext
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  • 11
    Online Resource
    Online Resource
    Test No. 443: Extended One-Generation Reproductive Toxicity Study (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264122550
    Language: English
    Pages: Online-Ressource (25 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 443 ; Étude étendue de toxicité pour la reproduction sur une génération
    Parallel Title: Parallelausg. Essai n 443 : Étude étendue de toxicité pour la reproduction sur une génération
    Keywords: Environment
    Abstract: This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and young and adult offspring. In the assay, sexually-mature males and females rodents (parental (P) generation) are exposed to graduated doses of the test substance starting 2 weeks before mating and continuously through mating, gestation and weaning of their pups (F1 generation). At weaning, pups are selected and assigned to cohorts of animals for reproductive/developmental toxicity testing (cohort 1), developmental neurotoxicity testing (cohort 2) and developmental immunotoxicity testing (cohort 3). The F1 offspring receive further treatment with the test substance from weaning to adulthood. Clinical observations and pathology examinations are performed on all animals for signs of toxicity, with special emphasis on the integrity and performance of the male and female reproductive systems and the health, growth, development and function of the offspring. Part of cohort 1 (cohort 1B) may be extended to include an F2 generation; in this case, procedures for F1 animals will be similar to those for the P animals.
    DOI: 10.1787/9789264122550-en
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  • 12
    Online Resource
    Online Resource
    Better Policies to Support Eco-innovation (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264096684
    Language: English
    Pages: Online-Ressource (304 p.)
    Series Statement: OECD Studies on Environmental Innovation
    Parallel Title: Erscheint auch als Better policies to support eco-innovation
    RVK:
    QT 000
    Keywords: Innovation ; Nachhaltige Entwicklung ; Technologiepolitik ; OECD-Staaten ; Technologietransfer ; Umweltschutz ; Clean Development Mechanism ; Public Private Partnership ; Fallstudie ; Environment ; OECD ; Umwelttechnik ; Forschungsförderung
    Abstract: Eco-innovation is more important than ever on the public policy agenda. It is a major driver for green growth and contributes to the environmental performance and economic development of OECD and developing countries alike. This report takes a pragmatic approach to policies that support the development and diffusion of eco-innovation. Building on the OECD Innovation Strategy, it argues that eco-innovation is not merely about technological developments: non-technical innovations matter as well. It acknowledges that policies do not operate in a vacuum and that they must take account of the contexts that influence the development and diffusion of eco-innovation, such as market structures. It explores links between eco-innovation policies and related fields such as industry, competition, and international cooperation. This work builds on an OECD inventory of eco-innovation policies in OECD countries and in China. It also draws on studies of select environment-friendly innovations, highlighting different patterns of development across countries. It also incorporates extensive international consultation on the topics of eco-innovation and green growth. The results from this publication will contribute to the Green Growth Strategy being developed by the OECD as a practical policy package for governments to harness the potential of greener growth. For more information on OECD work on eco-innovation, visit: www.oecd.org/greengrowth www.oecd.org/environment/innovation www.oecd.org/sti/innovation/green
    DOI: 10.1787/9789264096684-en
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  • 13
    Online Resource
    Online Resource
    Greening Household Behaviour : The Role of Public Policy (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264096875
    Language: English
    Pages: Online-Ressource (192 p.) , ill.
    Series Statement: OECD Studies on Environmental Policy and Household Behaviour
    Parallel Title: Parallelausg. Politique de l'environnement et comportement des ménages
    Parallel Title: Erscheint auch als Greening household behaviour
    RVK:
    MF 9150
    RVK:
    QW 300
    Keywords: Konsumentenverhalten ; Umweltbewusstsein ; Umweltpolitik ; OECD-Staaten ; Umweltschutz ; Haushalt ; Privater Verbrauch ; Ressourcenmanagement ; Wirtschaftliches Verhalten ; Environment ; Australien ; Kanada ; Tschechien ; Frankreich ; Italien ; Südkorea ; Mexiko ; Niederlande ; Industriestaaten ; Haushalt ; Privater Verbrauch ; Verbraucherverhalten ; Umweltbelastung ; Internationaler Vergleich
    Abstract: Developing growth strategies that promote greener lifestyles requires a good understanding of what factors affect people’s behaviour towards the environment. Recent OECD work based on periodic surveys of more than 10 000 households across a number of countries and areas represents a breakthrough by providing a common framework to collect unique empirical evidence for better policy design. This publication presents responses from the most recent round of the OECD survey implemented in 2011 in 5 areas (energy, food, transport, waste and water) and 11 countries: Australia, Canada, Chile, France, Israel, Japan, Korea, the Netherlands, Spain, Sweden and Switzerland. Analysis comparing the data across countries, policy conditions and households’ characteristics reveals which measures most effectively change behaviour. Each round of the survey also allows to track changes over time and to explore new emerging issues. The new survey confirms the importance of providing the right economic incentives for influencing our decisions. The findings indicate that “soft” measures such as labelling and public information campaigns also have a significant complementary role to play. Spurring desirable behaviour change requires a mix of these instruments. This book is a milestone for all those interested by the challenging question of ways to promote greener behaviour, from policy makers to individual citizens.
    DOI: 10.1787/9789264096875-en
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  • 14
    Online Resource
    Online Resource
    Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264122819
    Language: English
    Pages: Online-Ressource (16 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 488 ; Essais de mutations génétiques des cellules somatiques et germinales de rongeurs transgéniques
    Parallel Title: Parallelausg. Essai n 488 : Essais de mutations génétiques des cellules somatiques et germinales de rongeurs transgéniques
    Keywords: Environment
    Abstract: This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The transgenes contain reporter genes for the detection of various types of mutations induced by test substances. A negative control group and a minimum of 3 treatment groups of transgenic animals are treated for 28 consecutive days. Administration is usually followed by a 3-day period of time, prior to sacrifice, during which the agent is not administered and during which unrepaired DNA lesions are fixed into stable mutations. At the end of this 3-day period, the animals are sacrificed, genomic DNA is isolated from the tissue(s) of interest and purified. Mutations that have arisen during treatment are scored by recovering the transgene and analysing the phenotype of the reporter gene in a bacterial host deficient for the reporter gene. Mutant frequency, the reported parameter in these assays,is calculated by dividing the number of plaques/plasmids containing mutations in the transgene by the total number of plaques/plasmids recovered from the same DNA sample.
    DOI: 10.1787/9789264122819-en
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  • 15
    Online Resource
    Online Resource
    Paying for Biodiversity : Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version) (2011)
    Vienna : WWF Danube-Carpathian Programme
    Details
    ISBN: 9789264124967
    Language: Bulgarian
    Pages: Online-Ressource
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services
    Parallel Title: Parallelausg. Payer pour la biodiversité ; Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services
    Parallel Title: Parallelausg. Payer pour la biodiversité : Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Keywords: Environment
    DOI: 10.1787/9789264124967-bg
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  • 16
    Online Resource
    Online Resource
    Test No. 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069923
    Language: English
    Pages: Online-Ressource (25 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 201; Algues d'eau douce et cyanobactéries, essai d'inhibition de la croissance
    Parallel Title: Parallelausg. Essai n 201: Algues d'eau douce et cyanobactéries, essai d'inhibition de la croissance
    Keywords: Environment
    Abstract: The purpose of this test is to determine the effects of a substance on the growth of freshwater microalgae and/or cyanobacteria. Exponentially growing test organisms are exposed to the test substance in batch cultures over a period of normally 72 hours. The system response is the reduction of growth in a series of algal cultures exposed to, at least, five concentrations of a test substance. Three replicates at each test concentration should be used. The response is evaluated as a function of the exposure concentration in comparison with the average growth of control cultures. The cultures are allowed unrestricted exponential growth under nutrient sufficient conditions (two alternative growth media: the OECD and the AAP) and continuous fluorescent illumination. Growth and growth inhibition are quantified from measurements of the algal biomass as a function of time. The limit test corresponds to one dose level of 100 mg/L. This study includes: the determination, at least daily, of the algal biomass; the measure of the pH (at the beginning and at the end); microscopic observation. This Test Guideline describes two response variables: average specific growth rate, and yield.
    DOI: 10.1787/9789264069923-en
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  • 17
    Online Resource
    Online Resource
    Climate Change and Tourism Policy in OECD Countries (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264119598
    Language: English
    Pages: Online-Ressource (100 p.) , ill.
    Series Statement: OECD Studies on Tourism
    Keywords: Environment ; Industry and Services
    Abstract: Undertaken jointly with United Nations Environment Programme, the report analyses policies and issues related to climate change adaptation and mitigation in the tourism sector. It provides policy recommendations, with the objective to identify priority areas to be included in a framework for action in the area of climate change and tourism. A review of the state of policy-making on this important issue clearly indicates that greater efforts could be made by countries to understand the likely impacts of climate change on tourism; there is a low awareness of the tourism sector's climate change mitigation and adaptation needs; and that current policy, with few exceptions, is inadequate to the scale of the challenge, both on mitigation and adaptation.
    DOI: 10.1787/9789264119598-en
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  • 18
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    Benefits of Investing in Water and Sanitation : An OECD Perspective (2011)
    Paris : OECD Publishing
    Details
    ISBN: 9789264100817
    Language: English
    Pages: Online-Ressource (148 p.)
    Series Statement: OECD Studies on Water
    Parallel Title: Erscheint auch als Benefits of investing in water and sanitation
    DDC: 628.1
    Keywords: Wasserversorgung ; Kanalisation ; Abwasserwirtschaft ; Kosten-Nutzen-Analyse ; Entwicklungsländer ; Environment ; Finance and Investment ; Entwicklungsländer ; Wasserwirtschaft ; Wasserversorgung ; Sanitäranlage ; Wasserversorgung ; Sanitäranlage ; Abwasserbeseitigung
    Abstract: The provision of water supply, sanitation and wastewater services generates substantial benefits for public health, the economy and the environment. Benefit-to-cost ratios can be as high as 7 to 1 for basic water and sanitation services in developing countries. Wastewater treatment interventions, for example, generate significant benefits for public health, the environment and for certain economic sectors such as fisheries, tourism and property markets. The full magnitude of the benefits of water services is seldom considered for a number of reasons, including the difficulty in quantifying important non-economic benefits such as non-use values, dignity, social status, cleanliness and overall well-being. Also, information about the benefits of water services is usually hidden in the technical literature, where it remains invisible to key decision-makers in ministries. This report draws together and summarises existing information on the benefits of water and sanitation.
    DOI: 10.1787/9789264100817-en
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  • 19
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    Test No. 429: Skin Sensitisation : Local Lymph Node Assay (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071100
    Language: English
    Pages: Online-Ressource (20 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 429; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques
    Parallel Title: Parallelausg. Essai n 429: Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques
    Keywords: Environment
    Abstract: The basic principle underlying the Local Lymph Node Assay (LLNA) in mouse is that sensitizers induce a primary proliferation of lymphocytes in the auricular lymph nodes draining the site of chemical application. This proliferation is proportional to the dose applied and provides a measurement of sensitisation. The method described is based on the use of radioactive labelling to measure cell proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a negative control group treated with the vehicle only, and a positive control, as appropriate. The experimental schedule of the assay is during 6 days. Thereafter, the animals are killed and a cell suspension of lymph node cells is prepared. The incorporation of 3H-methyl thymidine is measured by ¦Â-scintillation counting as disintegrations per minute (DPM). The Test Guideline includes performance standards that can be used to evaluate the validation status of new and/or modified test methods that are functionally and mechanistically similar to the LLNA. A reduced LLNA approach which could use up to 40% fewer animals is also described as an option. This study includes: measurements (weighing, DPM), and clinical daily observations. Results are expressed as the Stimulation Index (SI).The SI is obtained by calculation and should be ¡Ý3 before classification of the test material as a skin sensitizer is warranted.
    DOI: 10.1787/9789264071100-en
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  • 20
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    Test No. 223: Avian Acute Oral Toxicity Test (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090897
    Language: English
    Pages: Online-Ressource (25 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 223 ; Oiseaux, essai de toxicité orale aigue͏̈
    Parallel Title: Parallelausg. Essai n 223 : Oiseaux, essai de toxicité orale aigue͏̈
    Keywords: Environment
    Abstract: This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only options are sequential testing procedures. The test method selected will depend on whether or not a definitive median dose (LD50) and slope of the dose-response curve are both needed. The limit dose test is the preferred test when toxicity is expected to be low and lethality is unlikely at the limit dose. The limit dose should be adequate for assessment purposes, and it is usually 2000 mg/kg-bwt. Five or ten birds are tested at the limit dose in addition to a control group. The LD50-slope test is the preferred test when regulatory or other requirements determine that the slope of the dose-response curve and/or the confidence interval is required in addition to an estimate of the LD50. This is a 3- or 4-stage test with 24 or 34 birds in addition to a control group. The LD50-only test is the preferred test when regulatory or other requirements determine that only the median lethal dose is required but neither the slope of the dose response curve or the confidence interval for the LD50 is required. This may be the appropriate test to estimate a percentile of a species sensitivity distribution of LD50s and to provide information for product labelling purposes. This test has two stages, with 14 birds in addition to a control group. Software to be used with TG 223. Click here. Software not part of the Mutual Acceptance of Data.
    DOI: 10.1787/9789264090897-en
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  • 21
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    Test No. 442B: Skin Sensitization : Local Lymph Node Assay: BrdU-ELISA (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090996
    Language: English
    Pages: Online-Ressource (15 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 442B ; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques; BrdU- ELISA
    Parallel Title: Parallelausg. Essai n 442B : Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques: BrdU- ELISA
    Keywords: Environment
    Abstract: The Local Lymph Node Assay: BrdU-ELISA (LLNA:BrdU-ELISA) is a non-radioactive modification to the LLNA method for identifying potential skin sensitizing test substances and measuring the proliferation of lymphocytes they induce in the auricular lymph nodes. The method described in mouse is based on the use of measuring 5-bromo-2-deoxyuridine (BrdU) content, an analogue of thymidine, as an indicator of this proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent negative control group and a positive control group. The experimental schedule is during 6 days. Thereafter, the animals are killed and a single cell suspension of lymph node cells (LNC) is prepared. The procedure for preparing the LNC is crucial, in particular for the small lymph nodes in NC animals. Then the BrdU content in DNA of lymphocytes is measured by ELISA using a commercial kit of by Flow Cytometry (FCM). This study includes: measurements (weighing, BrdU) and clinical daily observations. The results are expressed as the Stimulation Index (SI) obtained by calculation from the mean BrdU labelling index. The SI should be ≥1.6 for the ELISA method or ≥2.7 for the FCM method for identifying the test material as a potential skin sensitizer.
    DOI: 10.1787/9789264090996-en
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  • 22
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    Taxation, Innovation and the Environment (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264087637
    Language: English
    Pages: Online-Ressource (252 p.) , ill.
    Parallel Title: Druckausg.
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment; (Chinese version)
    Parallel Title: Parallelausg. La fiscalité, l'innovation et l'environnement
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment: (Chinese version)
    Parallel Title: Erscheint auch als Taxation, innovation and the environment
    RVK:
    QT 200
    Keywords: Ökosteuer ; Treibhausgas-Emissionen ; Emissionshandel ; OECD-Staaten ; Environment ; Taxation ; Umweltabgabe ; Umweltschutz ; Innovation ; Umweltpolitik ; Umweltsteuer ; Innovationsförderung ; Internationaler Vergleich
    Abstract: Solving the world’s environmental problems could take a significant toll on economic growth if only today’s technologies are available. We know that innovation – the creation and adoption of new cleaner technologies and know-how – provides a means to achieve local and global environmental goals at significantly lower costs. Innovation is also a major driver of economic growth. OECD governments are increasingly using environmentally related taxes because they are typically one of the most effective policy tools available. Exploring the relationship between environmentally related taxation and innovation is critical to understanding the full impacts of this policy instrument as well as one potential facet of “green growth.” By putting a price on pollution, do environmentally related taxes spur innovation? What types of innovation result? Does the design of the tax play a critical role? What is the effect of this innovation? In analysing these questions, this report draws on case studies that cover Japan, Korea, Spain, Sweden, Switzerland, the United Kingdom, Israel and others. It covers a wide set of environmental issues and technologies, as well as the economic and policy contexts. The research methods range from econometric analysis to interviews with business owners and executives. The report also explores the use of environmentally related taxes in OECD countries and outlines considerations for policymakers when implementing these taxes. Green growth policies can stimulate economic growth while preventing environmental degradation, biodiversity loss and unsustainable natural resource use. The results from this publication will contribute to the Green Growth Strategy being developed by the OECD as a practical policy package for governments to harness the potential of greener growth.
    DOI: 10.1787/9789264087637-en
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  • 23
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    Safety Assessment of Transgenic Organisms, Volume 4 : OECD Consensus Documents (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264096158
    Language: English
    Pages: Online-Ressource (336 p.)
    Series Statement: Harmonisation of Regulatory Oversight in Biotechnology
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Safety assessment of transgenic organisms ; Vol. 4
    RVK:
    WG 3450
    Keywords: Agriculture and Food ; Environment ; Science and Technology ; Transgene Pflanzen ; Umweltgefährdung ; Risikoanalyse
    Abstract: The books on “Safety Assessment of Transgenic Organisms” constitute a compilation of the OECD Biosafety Consensus Documents. When published, Volume 1 and 2 contained the documents issued before 2006; Volume 3 and 4 are a continuation of the compilation up to 2010. The OECD Biosafety Consensus Documents identify elements of scientific information used in the environmental safety and risk assessment of transgenic organisms which are common to OECD member countries and some non members associated with the work. This is intended to encourage information sharing, promote harmonised practices, and prevent duplication of effort among countries. These books offer ready access to those consensus documents which have been issued on the website thus far. As such, it should be of value to applicants for commercial uses of transgenic organisms (crops, trees, microorganisms), to regulators and risk assessors in national authorities, as well as the wider scientific community. More information on the OECD's work related to the biosafety of transgenic organisms is found at BioTrack Online (http://www.oecd.org/biotrack).
    DOI: 10.1787/9789264096158-en
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  • 24
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    Ensuring Environmental Compliance : Trends and Good Practices (Chinese version) (2010)
    Beijing : Chinese Environmental Science Press
    Details
    ISBN: 9787511103338
    Language: Chinese
    Pages: Online-Ressource (227 p.) , ill.
    Parallel Title: Parallelausg. Ensuring Environmental Compliance; Trends and Good Practices
    Parallel Title: Parallelausg. Faire respecter les normes environnementales ; Tendances et bonnes pratiques
    Parallel Title: Parallelausg. Ensuring Environmental Compliance: Trends and Good Practices
    Parallel Title: Parallelausg. Faire respecter les normes environnementales : Tendances et bonnes pratiques
    Keywords: Environment ; Governance
    DOI: 10.1787/9787511103338-zh
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  • 25
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    Test No. 317: Bioaccumulation in Terrestrial Oligochaetes (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090934
    Language: English
    Pages: Online-Ressource (30 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 3
    Parallel Title: Parallelausg. Essai n 317 ; Bioaccumulation chez les oligochètes terrestres
    Parallel Title: Parallelausg. Essai n 317 : Bioaccumulation chez les oligochètes terrestres
    Keywords: Environment
    Abstract: This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant (ks) and the elimination rate constant (ke). The test consists of two phases: the uptake (exposure) phase and the elimination (post-exposure) phase. An elimination phase is always required unless uptake of the test substance during the exposure phase has been insignificant. The test organisms are exposed to the test substance during the uptake phase. The test substance is incorporated into the soil; it is recommended to use the artificial soil described in the OECD Test Guideline 207 (Earthworm, acute toxicity test). The uptake phase should be of 14 days (enchytraeids) or 21 days (earthworms) unless it is demonstrated that steady state has been reached. For the elimination phase, the worms are transferred to a soil free of test substance. The elimination phase is generally of 21 days.
    DOI: 10.1787/9789264090934-en
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  • 26
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    Test No. 487: In Vitro Mammalian Cell Micronucleus Test (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264091016
    Language: English
    Pages: Online-Ressource (23 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 487 ; Essai in vitro de micronoyaux sur cellules de mammifères
    Parallel Title: Parallelausg. Essai n 487 : Essai in vitro de micronoyaux sur cellules de mammifères
    Keywords: Environment
    Abstract: The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells. Micronuclei may originate from acentric chromosome fragments (i.e. lacking a centromere), or whole chromosomes that are unable to migrate to the poles during the anaphase stage of cell division. The assay detects the activity of clastogenic and aneugenic test substances in cells that have undergone cell division during or after exposure to the test substance. This Test Guideline allows the use of protocols with and without the actin polymerisation inhibitor cytochalasin B. Cytochalasin B allows for the identification and selective analysis of micronucleus frequency in cells that have completed one mitosis, because such cells are binucleate. This Test Guideline also allows the use of protocols without cytokinesis block provided there is evidence that the cell population analysed has undergone mitosis.
    DOI: 10.1787/9789264091016-en
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  • 27
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    Test No. 233: Sediment-Water Chironomid Life-Cycle Toxicity Test Using Spiked Water or Spiked Sediment (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090910
    Language: English
    Pages: Online-Ressource (29 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 233 ; Essai de toxicité sur le cycle de vie des chironomes dans un système eau-sédiment chargé ou eau chargée-sédiment
    Parallel Title: Parallelausg. Essai n 233 : Essai de toxicité sur le cycle de vie des chironomes dans un système eau-sédiment chargé ou eau chargée-sédiment
    Keywords: Environment
    Abstract: This Guideline is designed to assess the effects of prolonged exposure of chemicals to the life-cycle of the sediment-dwelling freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to five concentrations of the test chemical in sediment-water systems. The test substance is spiked into the water or alternatively the sediment, and first instar larvae are subsequently introduced into test beakers in which the sediment and water concentrations have been stabilised. Chironomid emergence, time to emergence, and sex ratio of the fully emerged and alive midges are assessed. Emerged adults are transferred to breeding cages, to facilitate swarming, mating and oviposition. The number of egg ropes produced and their fertility are assessed. From these egg ropes, first instar larvae of the 2nd generation are obtained. These larvae are placed into freshly prepared test beakers (spiking procedure as for the 1st generation) to determine the viability of the 2nd generation through an assessment of their emergence, time to emergence and the sex ratio of the fully emerged and alive midges. All data are analysed either by a regression model to estimate the concentration that would cause X% reduction in the relevant endpoint, or by using hypothesis testing to determine a No Observed Effect Concentration (NOEC).
    DOI: 10.1787/9789264090910-en
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  • 28
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    Cutting Costs in Chemicals Management : How OECD Helps Governments and Industry (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264085930
    Language: English
    Pages: Online-Ressource (46 p)
    Parallel Title: Parallelausg. Réduire les coûts de gestion des produits chimiques ; Comment l'OCDE aide les gouvernements et l'industrie
    Parallel Title: Parallelausg. Réduire les coûts de gestion des produits chimiques : Comment l'OCDE aide les gouvernements et l'industrie
    Keywords: Environment ; Governance ; Industry and Services
    Abstract: The chemicals industry - including industrial chemicals, pharmaceuticals, pesticides, food and feed additives and cosmetics - is one of the world’s largest industrial sectors. Many chemical products are traded internationally. Varying national requirements can mean duplication of efforts and significant costs for the chemicals industry, as well as posing barriers to trade. By agreeing on test methods and data quality and sharing the workload of chemical safety testing and assessments, countries together achieve environmentally sustainable and cost-effective results. For non-clinical health and safety testing, for example, the results of such studies carried out on a chemical product in one OECD country must be accepted by the others as long as it was carried out in accordance with the OECD Test Guidelines and Principles of Good Laboratory Practice. This saves the chemicals industry the expense of duplicative testing for products that are marketed in more than one country. This report analyses the rigorous and comprehensive system for assessing and managing chemicals that helps governments and industry save about EUR 150 million each year, through “work sharing” facilitated by the OECD.
    DOI: 10.1787/9789264085930-en
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  • 29
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    Cities and Climate Change (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264091375
    Language: English
    Pages: Online-Ressource (276 p.) , ill.
    Parallel Title: Erscheint auch als Cities and climate change
    RVK:
    RB 10438
    RVK:
    RB 10627
    RVK:
    ZH 9150
    RVK:
    ZH 9316
    Keywords: Klimawandel ; Stadt ; Kommunalpolitik ; Kommunalverwaltung ; OECD-Staaten ; Klima ; Environment ; Governance ; Urban, Rural and Regional Development ; Klima ; Klimakatastrophe ; Klimaveränderung ; Klimawandel ; Stadt ; Klimaänderung
    Abstract: As the hubs of economic activity, cities drive the vast majority of the world’s energy use and are major contributors to global greenhouse gas emissions. Because they are home to major infrastructure and highly concentrated populations, cities are also vulnerable to the impacts of climate change, such as rising sea levels, warmer temperatures and fiercer storms. At the same time, better urban planning and policies can reduce energy use and greenhouse gas emissions and improve the resilience of urban infrastructure to climate change, thus shaping future trends. This book shows how city and metropolitan regional governments working in tandem with national governments can change the way we think about responding to climate change. The chapters analyse: trends in urbanisation, economic growth, energy use and climate change; the economic benefits of climate action; the role of urban policies in reducing energy demand, improving resilience to climate change and complementing global climate policies; frameworks for multilevel governance of climate change including engagement with relevant stakeholders; and the contribution of cities to “green growth”, including the “greening” of fiscal policies, innovation and jobs. The book also explores policy tools and best practices from both OECD and some non-member countries. Cities and Climate Change reveals the importance of addressing climate change across all levels of government. Local involvement through “climate-conscious” urban planning and management can help achieve national climate goals and minimise tradeoffs between environmental and economic priorities at local levels. The book will be relevant to policy makers, researchers, and others with an interest in learning more about urbanisation and climate change policy.
    DOI: 10.1787/9789264091375-en
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  • 30
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    Eco-Innovation in Industry : Enabling Green Growth (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264077225
    Language: English
    Pages: Online-Ressource (278 p.)
    Parallel Title: Parallelausg. L'éco-innovation dans l'industrie ; favoriser la croissance verte
    Parallel Title: Parallelausg. L'éco-innovation dans l'industrie : favoriser la croissance verte
    Parallel Title: Erscheint auch als Eco-innovation in industry
    RVK:
    AR 28300
    RVK:
    QT 200
    Keywords: Industrie ; Innovationsmanagement ; Umwelttechnik ; OECD-Staaten ; Environment ; Science and Technology ; Industry and Services ; Industrie ; Nachhaltigkeit ; OECD
    Abstract: Eco-innovation will be a key driver of industry efforts to tackle climate change and realise “green growth” in the post-Kyoto era. Eco-innovation calls for faster introduction of breakthrough technologies and for more systemic application of available solutions, including non-technological ones. It also offers opportunities to involve new players, develop new industries and increase competitiveness. Structural change in economies will be imperative in coming decades. This book presents the research and analysis carried out during the first phase of the OECD Project on Sustainable Manufacturing and Eco-innovation. Its aim is to provide benchmarking tools on sustainable manufacturing and to spur eco-innovation through better understanding of innovation mechanisms. It reviews the concepts and forms an analytical framework; analyses the nature and processes of eco-innovation; discusses existing sustainable manufacturing indicators; examines methodologies for measuring eco-innovation; and takes stock of national strategies and policy initiatives for eco-innovation.
    DOI: 10.1787/9789264077225-en
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  • 31
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    Test No. 442A: Skin Sensitization : Local Lymph Node Assay: DA (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090972
    Language: English
    Pages: Online-Ressource (16 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 442A ; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques; DA
    Parallel Title: Parallelausg. Essai n 442A : Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques: DA
    Keywords: Environment
    Abstract: The Local Lymph Node Assay: DA (LLNA: DA) is a non-radioactive modification to the LLNA method for identifying potential skin sensitizing test substances and measuring the proliferation of lymphocytes they induce in the auricular lymph nodes. The method, described in mouse (CBA/J strain), is based on measurement of the adenosine triphosphate (ATP) content by bioluminescence as an indicator of this proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent negative control group and, if appropriate, a positive control group. The experimental schedule is during 8 days. The time from animal sacrifice to measurement of ATP should not exceed 30 min. The procedure from excision of lymph nodes to ATP measurement should be kept uniform for each animal and completed within 20 minutes. The luciferin/luciferase method is applied to measure the bioluminescence in Relative Luminescence Units (RLU). This study includes: measurements (weighing, RLU), and clinical daily observations. The results are expressed as the Stimulation Index (SI) obtained by calculation. The SI should be ¡Ý1.8 before further evaluation of the test material as a potential skin sensitizer is warranted.
    DOI: 10.1787/9789264090972-en
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  • 32
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    Linkages between Environmental Policy and Competitiveness (2010)
    Paris : OECD Publishing
    Details
    Language: English
    Pages: 54 p. , 21 x 29.7cm
    Series Statement: OECD Environment Working Papers no.13
    Keywords: Environment
    Abstract: Debates exist between those who claim that environmental policy will impose additional burdens and costs on industries, thus impairing their competitiveness, and those who claim that improved environmental performance can spur competitiveness. These arguments often surface when new environmental policy regulation are considered, e.g. when the REACH Directive was introduced in Europe, or when a government is considering the introduction of a carbon tax. The report develops a conceptual framework to shed some light on this difficult debate. Competitiveness impacts of environmental policies may derive from the policy itself, or from the improvements of the environmental performance that derives from the policy. These impacts can be analysed at either firm or industry levels; they may differ over the short and long term. Globalisation, with the increasing role of MNEs and mobile capital and labour, is adding more complexity. This framework is used to decipher some of the messages that come out of empirical studies on these issues. Empirical evidence is mixed, and the paper identifies methodological and substantive reasons why empirical research fails to determine the relationship between environmental policy and competitiveness. Lessons derive from this literature review. Typically, even when implementing the environmental policy is clearly in the overall interest of society, the costs and benefits of the policy are unlikely to be equally shared among economic agents. While some win, individual firms or industries may stand to lose. Policy design should make sure that the adverse competitiveness impacts are not unnecessarily large, for example by paying attention to predictability, transition periods, and transaction costs. Specific measures to support the losers in their adjustment can also be developed. Sometimes measures to mitigate the adverse competitiveness impacts of an environmental policy are necessary to achieve political support for the policy. In those instances, the planned measures should be carefully analysed from several angles to ensure that they do not inadvertently hurt the efficiency and effectiveness of the original policy. More work is required to further explore these issues, which are consequential for the design, the implementation and the enforcement of environmental policies.
    DOI: 10.1787/218446820583
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  • 33
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    Test No. 417: Toxicokinetics (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070882
    Language: English
    Pages: Online-Ressource (20 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 417; Toxicocinétique
    Parallel Title: Parallelausg. Essai n 417: Toxicocinétique
    Keywords: Environment
    Abstract: This Test Guideline describes in vivo studies that provide information on mass balance, absorption, bioavailability, tissue distribution, metabolism, excretion, and basic toxicokinetic parameters [e.g. AUC], as well as supplemental approaches that may provide useful information on toxicokinetics. Information from toxicokinetic studies helps to relate concentration or dose to the observed toxicity and to understand its mechanism of toxicity. The test substance ("unlabelled" or "radiolabelled" forms) is normally administered by an oral route, but other routes of administration may be applicable. Single dose administration of the substance (preferably a minimum of two dose levels) may be adequate, but repeated dose may be needed in some circumstances. Toxicokinetic studies should preferably be carried out in the same species as that used in other toxicological studies performed with the substance (normally the rat, a minimum of 4 animals of one sex for each dose). Initial estimation of absorption can be achieved by mass balance determination, but further investigations such as intravenous (IV) administration and biliary excretion studies might be necessary. Bioavailability can be determined from plasma/blood kinetics of oral and IV groups. The percent of the total dose in tissues should at a minimum be measured at the termination of experiment,but additional time points may also be needed. Metabolites present at 5 % or greater of the administered dose should be identified. The rate and extent of excretion of the administered dose should be determined by measuring the percent recovered dose from urine, faeces and expired air.
    DOI: 10.1787/9789264070882-en
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    Test No. 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070080
    Language: English
    Pages: Online-Ressource (18 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 209; Boue activée, essai d'inhibition de la respiration (oxydation du carbone et de l'ammonium)
    Parallel Title: Parallelausg. Essai n 209: Boue activée, essai d'inhibition de la respiration (oxydation du carbone et de l'ammonium)
    Keywords: Environment
    Abstract: This Test Guideline is designed to assess the effects of a substance on micro-organisms from activated sludge of waste-water treatment plants by measuring their respiration rate (carbon and/or ammonium oxidation) as oxygen consumption. The test results may also serve as an indicator of suitable non-inhibitory concentrations of test substances to be used in biodegradability tests. The test allows the determination of ECx and/or NOEC values of the test substance. The inhibition of three different oxygen uptakes may be determined, i.e. total, heterotrophic only, and that due to nitrification in the absence and presence of N-allylthiourea, a specific nitrification inhibitor. For obtaining both NOEC and ECx, six controls and five treatment concentrations in a geometric series with five replicates are recommended. In each test vessel, test mixtures containing water, synthetic sewage feed and the test substance are incubated at the pH of 7.5 ±0.5 and the temperature within 20±2°C under forced aeration to keep the dissolved oxygen concentration above 60-70% saturation. The oxygen consumption is measured after 3 hours of exposure and additional measurements at 30 minutes of exposure can be performed in the case that the test substance is rapidly degraded.
    DOI: 10.1787/9789264070080-en
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  • 35
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    Taxation, Innovation and the Environment : (Chinese version) (2010)
    Beijing : Chinese Academy of Governance, China
    Details
    ISBN: 9787515000718
    Language: Chinese
    Pages: Online-Ressource (302 p.) , ill.
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment
    Parallel Title: Parallelausg. La fiscalité, l'innovation et l'environnement
    Keywords: Environment ; Taxation
    DOI: 10.1787/9787515000718-zh
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  • 36
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    Safety Assessment of Transgenic Organisms, Volume 3 : OECD Consensus Documents (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264095434
    Language: English
    Pages: Online-Ressource (324 p.)
    Series Statement: Harmonisation of Regulatory Oversight in Biotechnology
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Safety assessment of transgenic organisms ; Vol. 3
    RVK:
    WG 3450
    Keywords: Agriculture and Food ; Environment ; Science and Technology ; Transgene Pflanzen ; Umweltgefährdung ; Risikoanalyse
    Abstract: The books on “Safety Assessment of Transgenic Organisms” constitute a compilation of the OECD Biosafety Consensus Documents. When published, Volume 1 and 2 contained the documents issued before 2006; Volume 3 and 4 are a continuation of the compilation up to 2010. The OECD Biosafety Consensus Documents identify elements of scientific information used in the environmental safety and risk assessment of transgenic organisms which are common to OECD member countries and some non members associated with the work. This is intended to encourage information sharing, promote harmonised practices, and prevent duplication of effort among countries. These books offer ready access to those consensus documents which have been issued on the website thus far. As such, it should be of value to applicants for commercial uses of transgenic organisms (crops, trees, microorganisms), to regulators and risk assessors in national authorities, as well as the wider scientific community. More information on the OECD's work related to the biosafety of transgenic organisms is found at BioTrack Online (http://www.oecd.org/biotrack).
    DOI: 10.1787/9789264095434-en
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  • 37
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    Transition to a Low-Carbon Economy : Public Goals and Corporate Practices (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090231
    Language: English
    Pages: Online-Ressource (116 p.) , ill.
    Parallel Title: Parallelausg. La transition vers une économie sobre en carbone ; objectifs publics et pratiques des entreprises
    Parallel Title: Parallelausg. La transition vers une économie sobre en carbone : objectifs publics et pratiques des entreprises
    Parallel Title: Erscheint auch als Transition to a low-carbon economy
    RVK:
    QT 800
    Keywords: Klimawandel ; Umweltmanagement ; OECD-Staaten ; Environment ; Finance and Investment ; Industry and Services ; OECD ; Umweltbezogenes Management ; Klimaänderung
    Abstract: Companies are increasingly aware of the need to address climate change. However, while many companies are taking action to address climate change, many others are still lagging behind. This report surveys responsible business practices addressing climate change and driving the shift to a low-carbon economy. It summarises policies, regulations and other instruments in support of a low carbon economy in OECD countries and emerging economies, and analyses corporate responses to these drivers. Using the principles of responsible business conduct identified in the OECD Guidelines for Multinational Enterprises, this report reviews three key areas of corporate action: accounting for greenhouse gas emissions; achieving emissions reductions; and engaging suppliers, consumers and other stakeholders.
    DOI: 10.1787/9789264090231-en
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  • 38
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    Integración de la Adaptación en la Cooperación para el Desarrollo : Guía sobre Políticas (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264088320
    Language: Spanish
    Pages: Online-Ressource (212 p.)
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation; Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement ; Document d'orientation
    Parallel Title: Parallelausg. Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento; Guia para o Desenvolvimento de Políticas
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation: Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement : Document d'orientation
    Parallel Title: Parallelausg. Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento: Guia para o Desenvolvimento de Políticas
    Keywords: Environment ; Development
    Abstract: El cambio climático es una amenaza seria y a largo plazo que puede afectar a cualquier parte del mundo. Su impacto negativo golpeará a los países pobres y a las capas de población más desfavorecidas de manera desproporcionada, complicando aún más el logro de sus objetivos de desarrollo. La guía Integración de la Adaptación en la Cooperación para el Desarrollo ofrece información esencial y consejos sobre cómo facilitar la integración de la adaptación al cambio climático en los procesos de desarrollo. Los objetivos de esta guía son los siguientes: i) facilitar la comprensión de las implicaciones del cambio climático en la práctica del desarrollo y promover la necesidad asociada de integrar la adaptación al cambio climático en las políticas y prácticas de desarrollo tanto de los organismos de cooperación como de los países socios, ii) identificar los enfoques más adecuados para integrar la adaptación al cambio climático en las políticas de desarrollo a nivel nacional, sectorial y de proyecto, tanto en zonas urbanas como en zonas rurales, y iii) determinar modalidades prácticas para que los donantes apoyen a los países socios en sus esfuerzos para reducir su vulnerabilidad a la variabilidad climática y el cambio climático. Aunque los esfuerzos por integrar la adaptación al cambio climático ha de ser dirigido por los países socios, los donantes internacionales tienen un papel crítico que desempeñar en el apoyo a esos esfuerzos. Esta guía para la orientación de políticas está destinada especialmente a responsables políticos, a profesionales de organismos de cooperación al desarrollo y sus contrapartes en los gobiernos de los países, y a otras partes interesadas, tales como organizaciones no gubernamentales.
    DOI: 10.1787/9789264088320-es
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  • 39
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    OECD Environmental Performance Reviews: Luxembourg 2010 (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264077287
    Language: English
    Pages: Online-Ressource (210 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE; Luxembourg 2010
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE: Luxembourg 2010
    Keywords: Environment ; Luxembourg
    Abstract: OECD's 2010 review of Luxembourg's environmental conditions and progress in air, water, waste and materials management; nature and biodiversity; the environment-economy interface; the environment-social interface; and international commitments and co-operation. The analyses presented are supported by a broad range of economic and environmental data and include recommendations for further environmental and sustainable development progress.
    DOI: 10.1787/9789264077287-en
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  • 40
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    OECD Environmental Performance Reviews: Japan 2010 (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264087873
    Language: English
    Pages: Online-Ressource (196 p.)
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE; Japon 2010
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE: Japon 2010
    Keywords: Environment ; Japan
    Abstract: This 2010 review of Japan's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. It includes coverage of policy for greening growth, implementation of environmental policies, climate change, waste management and the 3Rs (reduce, reuse, recycle), and nature and biodiversity. The review finds that since the last review, Japan has made steady progress in addressing a range of environmental issues, notably air and water pollution, and the management of chemicals and waste. The energy intensity of the economy has continued to decrease, particularly in the industrial sector, and is among the lowest in OECD countries. Material intensity has also decreased. At the same time, several more complex, long-term challenges have come to the fore: climate change, sound waste, materials management, and biodiversity conservation. Much of the last decade was characterised by sluggish economic growth, and environment and green innovation are targeted as key drivers of future growth and job creation in Japan's New Growth Strategy.
    DOI: 10.1787/9789264087873-en
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  • 41
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    Advancing the Aquaculture Agenda : Workshop Proceedings (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264088726
    Language: English
    Pages: Online-Ressource (428 p.)
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Advancing the aquaculture agenda
    Keywords: Aquakultur ; OECD-Staaten ; Agriculture and Food ; Environment ; Aquakultur ; Nachhaltigkeit ; Fischereipolitik
    Abstract: Aquaculture now provides more than 50% of the global supply of fisheries products for direct human consumption. This conference proceedings addresses key policy challenges of the aquaculture sector. Policy makers, academics, industry representatives, NGOs and international organisations gathered to discuss the critical economic, environmental and social aspects of aquaculture. This publication presents a selection of key issues covered by the workshop and includes a large number of country case studies, which provide specific examples of national approaches to aquaculture management.
    DOI: 10.1787/9789264088726-en
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  • 42
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    Paying for Biodiversity : Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090279
    Language: English
    Pages: Online-Ressource (196 p.)
    Parallel Title: Druckausg.
    Parallel Title: Parallelausg. Payer pour la biodiversité ; Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Parallel Title: Parallelausg. Payer pour la biodiversité : Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Parallel Title: Erscheint auch als Karousakis, Katia Paying for biodiversity
    RVK:
    QT 000
    Keywords: Artenvielfalt ; Umwelt ; Umweltökonomik ; Umweltpolitik ; Kosten-Wirksamkeits-Analyse ; Environment ; Biodiversität ; Umweltpolitik ; Umweltökonomie
    Abstract: Biodiversity and ecosystem services provide tangible benefits for society, such as food provisioning, water purification, genetic resources or climate regulation. These services provide critical life support functions and contribute to human health, well being and economic growth. Yet biodiversity is declining worldwide and, in some areas, this loss is accelerating. The need for policies that promote the conservation and sustainable use of biodiversity and ecosystem services is more important than ever. Payments for Ecosystem Services (PES) is a direct and flexible incentive-based mechanism under which the user or beneficiary of an ecosystem service makes a direct payment to an individual or community whose land use decisions have an impact on the ecosystem service provision. Interest in PES has been increasing rapidly over the past decade: PES are proliferating worldwide and there are already more than 300 programmes in place today at national, regional and local levels. Drawing on the literature concerning effective PES and on more than 30 case studies from both developed and developing countries, this book aims to identify good practice in the design and implementation of PES programmes so as to enhance their environmental and cost effectiveness. It addresses the following questions: Why are PES useful and how do they work? How can they be made most effective environmentally and how can their cost-effectiveness be maximised? What are the different potential sources of finance for PES programmes, and how can they be secured? and What are the lessons learned from existing PES programmes and insights for future programmes, including international PES?
    DOI: 10.1787/9789264090279-en
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  • 43
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    Greener and smarter : ICTs, the environment and climate change (2010)
    Paris : OECD Publishing
    Details
    Language: English
    Pages: 54 S.
    Additional Material: graph. Darst., Tab., Lit.Hinw.
    Edition: Online-Ausg. Online Ressource
    Series Statement: OECD green growth papers 2010, 01
    Series Statement: Industry and innovation
    Keywords: Informationstechnik ; Kommunikationstechnik ; Bedeutung ; Rolle ; Wirkung ; Auswirkung ; Klimaänderung ; Umwelt ; Ökologie ; Wirtschaftswachstum ; Umwelttechnik ; Produktion ; Branche ; Erwärmung ; Environment ; Science and Technology ; Amtsdruckschrift ; Arbeitspapier ; Graue Literatur
    Abstract: Information and communication technologies (ICTs) are a key enabler of “green growth” in all sectors of the economy. They are a key part of government strategies for a sustainable economic recovery. This report looks at how ICTs can improve their own environmental performance, and how they can be used to improve environmental performance throughout the economy and society. Direct environmental impacts of ICTs are considerable in areas such as energy use, materials throughput and end-of-life treatment. Government “green ICT” policies can be instrumental in promoting life-cycle approaches for improved R&D and design of ICT goods, services and systems. Innovative ICT applications enable sustainable production and consumption across the entire economy. The potential for improving environmental performance targets specific products, but also entire systems and industry sectors, e.g. construction, transport, energy.
    DOI: 10.1787/5k9h3635kdbt-en
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  • 44
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    Guidance on Sustainability Impact Assessment (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264086913
    Language: English
    Pages: Online-Ressource (32 p.)
    Parallel Title: Parallelausg. Document d'orientation pour les études d'impact sur la durabilité
    Keywords: Environment ; Social Issues/Migration/Health ; Economics
    Abstract: This publication offers a general introduction to sustainability impact assessment, which is an approach for exploring the combined economic, environmental and social impacts of a range of proposed policies, programmes, strategies and action plans. Such assessments can also assist decision-making and strategic planning throughout the entire policy cycles. It is not an in-depth or detailed user manual, but rather outlines basic principles and process steps of sustainability impact assessments, drawing on examples from Switzerland, Belgium and the European Commission, among others. This publication is a valuable source of information for policy makers on sustainability impact assessments.
    DOI: 10.1787/9789264086913-en
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  • 45
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    Test No. 439: In Vitro Skin Irritation : Reconstructed Human Epidermis Test Method (2010)
    Paris : OECD Publishing
    Details
    ISBN: 9789264090958
    Language: English
    Pages: Online-Ressource (18 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 439 ; Irritation cutanée in vitro ; Essai sur épiderme humain reconstitué
    Parallel Title: Parallelausg. Essai n 439 : Irritation cutanée in vitro : Essai sur épiderme humain reconstitué
    Keywords: Environment
    Abstract: This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2. It is based on reconstructed human epidermis (RhE), which in its overall design closely mimics the biochemical and physiological properties of the upper parts of the human skin. Cell viability is measured by enzymatic conversion of the vital dye MTT into a blue formazan salt that is quantitatively measured after extraction from tissues. Irritant test substances are identified by their ability to decrease cell viability below defined threshold levels (below or equal to 50% for UN GHS Category 2). This Test Guideline also includes a set of Performance Standards for the assessment of similar and modified RhE-based test methods. There are three validated test methods that adhere to this Test Guideline. Depending on the regulatory framework and the classification system in use, this procedure may be used to determine the skin irritancy of test substances as a stand-alone replacement test for in vivo skin irritation testing, or as a partial replacement test, within a tiered testing strategy.
    DOI: 10.1787/9789264090958-en
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  • 46
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    OECD Environmental Performance Reviews: Turkey 1999 (1999)
    Paris : OECD Publishing
    Details
    ISBN: 9789264173804
    Language: English
    Pages: Online-Ressource (188 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Turquie 1999
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Turquie 1999
    Keywords: Environment ; Turkey
    Abstract: This review of Turkey's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264173804-en
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  • 47
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    OECD Environmental Performance Reviews: Russian Federation 1999 (1999)
    Paris : OECD Publishing
    Details
    ISBN: 9789264180116
    Language: English
    Pages: Online-Ressource (232 p.)
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Fédération de Russie 1999
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Fédération de Russie 1999
    Keywords: Environment ; Russian Federation
    Abstract: This review of the Russian Federation's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264180116-en
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  • 48
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    OECD Environmental Performance Reviews: Denmark 1999 (1999)
    Paris : OECD Publishing
    Details
    ISBN: 9789264172548
    Language: English
    Pages: Online-Ressource (224 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Danemark 1999
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Danemark 1999
    Keywords: Environment ; Denmark
    Abstract: This review of Denmark's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264172548-en
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  • 49
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    Energy: The Next Fifty Years (1999)
    Paris : OECD Publishing
    Details
    ISBN: 9789264173163
    Language: English
    Pages: Online-Ressource (164 p.) , ill.
    Parallel Title: Parallelausg. Énergie ; les cinquante prochaines années
    Parallel Title: Parallelausg. Énergie : les cinquante prochaines années
    Keywords: Energy ; Environment ; Economics
    Abstract: How long will conventional fossil fuels remain the predominant source of energy? Does nuclear power have a future? What new energy technologies are emerging on the horizon? What are the implications of the growing role played by developing countries as producers and users of energy? What can be done to avoid international energy crises in the future? How will the information society affect the production and use of energy? And what will be the long-term implications of international environmental agreements for a sustainable energy future? Endeavours to set world energy on a sustainable footing are entering a critical phase. By 2050 the energy landscape could be completely transformed. A highly diversified mix of conventional and new fuels will be in use; unprecedented levels of energy efficiency in transport systems, housing and other infrastructures will likely have been attained; and people could at last be reaping the rewards of environmentally responsible lifestyles. But such a shift towards sustainable use of energy will take decades to achieve. This book reviews the options likely to shape the energy picture over the next half-century, and assesses some of the key issues -- economic, social, technological, environmental -- that decision-makers in government and corporations will need to address in the very near future.
    DOI: 10.1787/9789264173163-en
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  • 50
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    OECD Environmental Performance Reviews: Czech Republic 1999 (1999)
    Paris : OECD Publishing
    Details
    ISBN: 9789264172166
    Language: English
    Pages: Online-Ressource (204 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; République Tchèque 1999
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : République Tchèque 1999
    Keywords: Environment ; Czech Republic
    Abstract: This review of the Czech Republic's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264172166-en
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  • 51
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    Test No. 212: Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070141
    Language: English
    Pages: Online-Ressource (20 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 212; Poisson, essai de toxicité à court terme aux stades de l'embryon et de l'alevin
    Parallel Title: Parallelausg. Essai n 212: Poisson, essai de toxicité à court terme aux stades de l'embryon et de l'alevin
    Keywords: Environment
    Abstract: In this Short-term Toxicity Test on Fish Embryo and Sac-Fry Stages, the life stages from the newly fertilized egg to the end of the sac-fry stage are exposed. The embryo and sac-fry stages of fish are exposed to five concentrations of the test substance dissolved in water. A choice, depending on the nature of the test substance, is possible between a semi-static and a flow-through procedure. The test starts with placing at least 30 fertilised eggs divided equally between at least three replicate test chambers per concentration, and is terminated just before the yolk-sac of any larvae in any of the test chambers has been completely absorbed or before mortalities by starvation start in controls. Lethal and sub-lethal effects are assessed and compared with control values to determine the lowest observed effect concentration and hence the no observed effect concentration. Alternatively, they may be analysed using a regression model in order to estimate the concentration that would cause a given percentage effect. The study report should include: the daily counting of the offspring, the daily recording of the parent mortality, the weekly measurement of oxygen concentration, temperature, and pH values; and the determination of the concentrations of test substance. It should also include the observations of abnormal appearance, abnormal behaviour, hatching and survival...
    DOI: 10.1787/9789264070141-en
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    Test No. 213: Honeybees, Acute Oral Toxicity Test (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070165
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 213; Abeille domestique, essai de toxicité aigue͏̈ par voie orale
    Parallel Title: Parallelausg. Essai n 213: Abeille domestique, essai de toxicité aigue͏̈ par voie orale
    Keywords: Environment
    Abstract: This Test Guideline is a laboratory test method, designed to assess the oral acute toxicity of pesticides and other chemicals, to adult worker honeybees. Adult worker honeybees are exposed to five doses in a geometric series of the test substance dispersed in sucrose solution. A minimum of three replicate test groups, each of ten bees, should be dosed with each test concentration. A toxic standard (usually dimethoate) should be included in the test series. The bees are then fed the same diet, free of the test substance. The limit test corresponds to one dose level of 100 ìg active ingredient/bee. Mortality is recorded daily during at least 48 hours and compared with control values. If the mortality rate is increasing between 24 and 48h whilst control mortality remains at an accepted level it is appropriate to extend the duration of the test to a maximum of 96h. The study report should include the amount of diet consumed per group and the observation of all abnormal behavioural. The results are analysed in order to calculate the LD50 at 24h and 48h and, in case the study is prolonged, at 72h and 96h.
    DOI: 10.1787/9789264070165-en
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    Test No. 214: Honeybees, Acute Contact Toxicity Test (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070189
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 214; Abeille domestique, essai de toxicité aigue͏̈ par contact
    Parallel Title: Parallelausg. Essai n 214: Abeille domestique, essai de toxicité aigue͏̈ par contact
    Keywords: Environment
    Abstract: This Test Guideline is a laboratory test method, designed to assess the acute contact toxicity of pesticides and other chemicals to adult worker honeybees. Anaesthetized adult worker honeybees are exposed to five doses in a geometric series of the test substance dissolved in appropriate carrier (in total a volume of 1 ml), by direct application to the thorax (droplets). A minimum of three replicate test groups, each of ten bees, should be dosed with each test concentration. A toxic standard (usually dimethoate) should be included in the test series. The limit test corresponds to one dose level of 100 ìg active ingredient/bee. The test duration is 48h. Mortality is recorded daily during at least 48 hours and compared with control values. If the mortality rate is increasing between 24 and 48h whilst control mortality remains at an accepted level, it is appropriate to extend the duration of the test to a maximum of 96h. The results are analysed in order to calculate the LD50 at 24h and 48h and, in case the study is prolonged, at 72h and 96h.
    DOI: 10.1787/9789264070189-en
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  • 54
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    Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070707
    Language: English
    Pages: Online-Ressource (10 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 408; Toxicité orale à doses répétées - rongeurs; 90 jours
    Parallel Title: Parallelausg. Essai n 408: Toxicité orale à doses répétées - rongeurs: 90 jours
    Keywords: Environment
    Abstract: This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose 28-day toxicity tests. The method is based on the repeated oral administration of the substance of interest over a prolonged period (one dose level daily during 90 days). This Test Guideline is intended primarily for use with rodents (rat preferably). At least 20 animals (10 female and 10 male) should be used for each test group. Three concentrations, at least, should be used. The test compound is administered by gavage or via the diet or drinking water. A limit test may be performed if no effects would be expected at a dose of 1000 mg/kg bw/d. The results of this study include: measurements (weighing at least once a week, food and water consumption) and daily and detailed observations (ophtalmological examination, haematology, clinical biochemistry and urinalysis), each day preferably at the same time; as well as gross necropsy and histopathology. A number of endocrine-related measurements, particularly relevant to thyoid function have been added in 2018. A properly conducted 90-day subchronic test should provide a satisfactory estimation of a no-effect level.
    DOI: 10.1787/9789264070707-en
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  • 55
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    Sustainable Development : OECD Policy Approaches for the 21st Century (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264174283
    Language: English
    Pages: Online-Ressource (184 p.) , ill.
    Keywords: Environment ; Economics
    Abstract: Since the Rio Earth Summit in 1992, sustainability has emerged as an over-arching policy goal in the OECD Secretariat and in its Member countries. Real progress depends upon the integration of environmental and social goals with economic ones. This publication provides an overview and analysis of trends and identifies policy gaps and trade-offs that have been encountered and points to future options. The authors document positive trends which have emerged signalling greater sustainability, as well as areas where progress has proved more elusive. While the main focus is the OECD region, expanding linkages -- among all countries and regions -- form an important part of the story. The coverage of the volume reflects the OECD's diverse subject matter expertise, and some of the interdisciplinary synergies that the Organisation can generate. Part I of this two-part volume concentrates on socio-economic issues, including the integration of economics and environment; trade and environment; changing consumption and production patterns; assessing environmental performance; development co-operation; and the evolution of aid agencies since Rio. Part II takes an in-depth look at nine sectoral issues: energy; transport; agriculture; toxic chemicals; climate change; nuclear energy; urbanisation; biotechnology; and education. In short, this publication gives essential keys to meet the major challengeof the 21st century: helping to make sustainability a reality.
    DOI: 10.1787/9789264174283-en
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  • 56
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    Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070721
    Language: English
    Pages: Online-Ressource (9 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 409; Toxicité orale à doses répétées - non-rongeurs; 90 jours
    Parallel Title: Parallelausg. Essai n 409: Toxicité orale à doses répétées - non-rongeurs: 90 jours
    Keywords: Environment
    Abstract: This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose 28-day toxicity tests. The method is based on the repeated oral administration of the substance of interest over a prolonged period (one dose level daily during 90 days). This Test Guideline is intended primarily for use with non-rodents species. The commonly used non-rodent species is the dog (the beagle is frequently used). At least 8 animals (4 female and 4 male) should be used for each test group. Three concentrations, at least, should be used. The test compound is administered in the diet or in the drinking water, by gavage or in capsules. A limit test may be performed if no effects would be expected at a dose of 1000 mg/kg bw/d. The results of this study include: measurements (weighing at least once a week, food/water consumption) and daily (preferably at the same time) and detailed observations (ophtalmological examination, haematology, clinical biochemistry and urinalysis), as well as gross necropsy and histopathology. A properly conducted 90-day subchronic test should provide a satisfactory estimation of a no-effect level.
    DOI: 10.1787/9789264070721-en
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  • 57
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    OECD Environmental Performance Reviews: Switzerland 1998 (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264163591
    Language: English
    Pages: Online-Ressource (228 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Keywords: Environment ; Switzerland
    Abstract: This review of Switzerland's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264163591-en
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  • 58
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    OECD Environmental Performance Reviews: Belgium 1998 (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264163522
    Language: English
    Pages: Online-Ressource (228 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Belgique 1998
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Belgique 1998
    Keywords: Environment ; Belgium
    Abstract: This review of Belgium's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264163522-en
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  • 59
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    OECD Environmental Performance Reviews: Australia 1998 (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264162693
    Language: English
    Pages: Online-Ressource (212 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Australie 1998
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Australie 1998
    Keywords: Environment ; Australia
    Abstract: This report evaluates Australia's progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264162693-en
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  • 60
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    OECD Environmental Performance Reviews: Mexico 1998 (1998)
    Paris : OECD Publishing
    Details
    ISBN: 9789264162594
    Language: English
    Pages: Online-Ressource (220 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE ; Mexique 1998
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE : Mexique 1998
    Keywords: Environment ; Mexico
    Abstract: This review of Mexico's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. The analyses presented are supported by a broad range of economic and environmental data.
    DOI: 10.1787/9789264162594-en
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  • 61
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    Test No. 476: In vitro Mammalian Cell Gene Mutation Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071322
    Language: English
    Pages: Online-Ressource (10 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 476; Essai in vitro de mutation génique sur des cellules de mammifères
    Parallel Title: Parallelausg. Essai n 476: Essai in vitro de mutation génique sur des cellules de mammifères
    Keywords: Environment
    Abstract: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In the cell lines the most commonly-used genetic endpoints measure mutation at thymidine kinase (TK) and hypoxanthine-guanine phosphoribosyl transferase (HPRT), and a transgene of xanthineguanine phosphoribosyl transferase (XPRT). The TK, HPRT and XPRT mutation tests detect different spectra of genetic events. Cells in suspension or monolayer culture are exposed to, at least four analysable concentrations of the test substance, both with and without metabolic activation, for a suitable period of time. They are subcultured to determine cytotoxicity and to allow phenotypic expression prior to mutant selection. It is recommended to utilise at least 106cells. Cytotoxicity is usually determined by measuring the relative cloning efficiency (survival) or relative total growth of the cultures after the treatment period. The treated cultures are maintained in growth medium for a sufficient period of time, characteristic of each selected locus and cell type, to allow near-optimal phenotypic expression of induced mutations. Mutant frequency is determined by seeding known numbers of cells in medium containing the selective agent to detect mutant cells, and in medium without selective agent to determine the cloning efficiency (viability). After a suitable incubation time, colonies are counted.
    DOI: 10.1787/9789264071322-en
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  • 62
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    Test No. 474: Mammalian Erythrocyte Micronucleus Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071285
    Language: English
    Pages: Online-Ressource (10 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 474; Le test de micronoyaux sur les érythrocytes de mammifères
    Parallel Title: Parallelausg. Essai n 474: Le test de micronoyaux sur les érythrocytes de mammifères
    Keywords: Environment
    Abstract: The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents (mice or rats). The purpose of the micronucleus test is to identify substances (liquid or solid) that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments or whole chromosomes. An increase in the frequency of micronucleated polychromatic erythrocytes in treated animals is an indication of induced chromosome damage. Animals are exposed to the test substance by an appropriate route (usually by gavage using a stomach tube or a suitable intubation cannula, or by intraperitoneal injection). Bone marrow and/or blood cells are collected, prepared and stained. Preparations are analyzed for the presence of micronuclei. Each treated and control group must include at least 5 analysable animals per sex. Administration of the treatments consists of a single dose of test substance or two daily doses (or more). The limit dose is 2000 mg/kg/body weight/day for treatment up to 14 days, and 1000 mg/kg/body weight/day for treatment longer than 14 days.
    DOI: 10.1787/9789264071285-en
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  • 63
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    Test No. 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071520
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 486; Essai de synthèse non programmée de l'ADN (UDS) sur des hépatocytes de mammifères in vivo
    Parallel Title: Parallelausg. Essai n 486: Essai de synthèse non programmée de l'ADN (UDS) sur des hépatocytes de mammifères in vivo
    Keywords: Environment
    Abstract: The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage induced by chemical substances (solid or liquid) or physical agents in the liver. The test is usually based on the incorporation of tritium-labelled thymidine, 3H-TdR, (during 3-8 hours) into the DNA of liver cells which have a low frequency of cells in the S-phase of the cell cycle. The uptake of 3H-TdR is usually determined by autoradiography. Rats are commonly used, and the number of animals should be at least three analysable animals per group. Normally, at least two dose levels are used. A limit test may be performed if no effects would be expected at a dose of 2000 mg/kg bw/d. Test substances are generally administered as a single treatment by gavage using a stomach tube or a suitable intubation cannula. Liver cells are prepared from treated animals 12-16 hours after dosing of animal. After autoradiography, normally 100 cells are scored from each animal from at least two slides. A positive result from the UDS test with mammalian liver cells in vivo indicates that a substance induces DNA damage in mammalian liver cells in vivo that can be repaired by unscheduled DNA synthesis in vitro. A negative result indicates that, under the test conditions, the test substance does not induce DNA damage that is detectable by this test.
    DOI: 10.1787/9789264071520-en
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    Test No. 424: Neurotoxicity Study in Rodents (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071025
    Language: English
    Pages: Online-Ressource (15 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 424; Étude de neurotoxicité
    Parallel Title: Parallelausg. Essai n 424: Étude de neurotoxicité
    Keywords: Environment
    Abstract: This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically addresses the daily oral administration, by gavage, (in the diet, in drinking water or by capsules) of the test substance. When the study is conducted as a separate study, at least 20 animals (10 females and 10 males) should be used in each dose. At least three dose groups and a control group should generally be used. Dose levels should be selected by taking into account any previously observed toxicity and kinetic data available for the test compound or related materials. The dosing regimen may be 28 days, subchronic (90 days) or chronic (1 year or longer). The procedures set out in this Test Guideline may also be used for an acute neurotoxicity study. The limit test corresponds to one dose level of at least 1000 mg/kg body weight. The results of this study include measurements (weighing, food /water consumption), functional tests, and, at least, daily detailed observations (Ophthalmology, haematology, clinical biochemistry and histopathology). At least five males and five females, selected from test group, should be perfused in situ and used for detailed neurohistopathology at the end of the study. The findings of the study should be evaluated in terms of the incidence, severity and correlation of neurobehavioural and neuropathological effects (neurochemical or electrophysiological effects as well if supplementary examinations are included) and any other adverse effects observed.
    DOI: 10.1787/9789264071025-en
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    Test No. 483: Mammalian Spermatogonial Chromosome Aberration Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071469
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 483; Toxicologie génétique; Essai cytogénétique sur cellules germinales de mammifère
    Parallel Title: Parallelausg. Essai n 483: Toxicologie génétique: Essai cytogénétique sur cellules germinales de mammifère
    Keywords: Environment
    Abstract: This test measures chromosome events in spermatogonial germ cells and is, therefore, expected to be predictive of induction of inheritable mutations in germ cells. Male Chinese hamsters and mice are commonly used. Animals are exposed to the test substance (liquid or solid) by an appropriate route of exposure, usually by gavage or by intraperitoneal injection. Then, they are sacrificed at appropriate times after treatment. Each treated and control group must include at least five analysable males. Test substances are preferably administered once or twice but they may also be administered as a split dose to facilitate administering a large volume of material. Prior to sacrifice, animals are treated with a metaphase-arresting agent. Chromosome preparations are then made from germ cells and stained, and metaphase cells are analyzed for chromosome aberrations. A limit test may be performed if no effects would be expected at a dose of 2000 mg/kg bw/d. Positive results from the in vivo spermatogonial chromosome aberration test indicate that a substance induces chromosome aberrations in the germ cells of the species tested.
    DOI: 10.1787/9789264071469-en
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    Test No. 471: Bacterial Reverse Mutation Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071247
    Language: English
    Pages: Online-Ressource (11 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 471; Essai de mutation réverse sur des bactéries
    Parallel Title: Parallelausg. Essai n 471: Essai de mutation réverse sur des bactéries
    Keywords: Environment
    Abstract: The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and Escherichia coli to detect point mutations by base substitutions or frameshifts. The principle of this bacterial reverse mutation test is that it detects mutations which revert mutations present in the test strains and restore the functional capability of the bacteria to synthesize an essential amino acid. Suspensions of bacterial cells are exposed to the test substance (liquid or solid) in the presence and in the absence of an exogenous metabolic activation system. At least five different analysable concentrations of the test substance should be used. The recommended maximum test concentration for soluble non-cytotoxic substances is 5 mg/plate or 5 ml/plate. There are two methods: the plate incorporation method and the preincubation method. For both techniques, after two or three days of incubation at 37°C, revertant colonies are counted and compared to the number of spontaneous revertant colonies on solvent control plates.
    DOI: 10.1787/9789264071247-en
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  • 67
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    Test No. 473: In vitro Mammalian Chromosome Aberration Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071261
    Language: English
    Pages: Online-Ressource (10 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 473; Essai d'aberration chromosomique in vitro chez les mammifères
    Parallel Title: Parallelausg. Essai n 473: Essai d'aberration chromosomique in vitro chez les mammifères
    Keywords: Environment
    Abstract: The purpose of the in vitro chromosome aberration test is to identify agents that cause structural chromosome aberrations in cultured mammalian somatic cells. Structural aberrations may be of two types: chromosome or chromatid. The in vitro chromosome aberration test may employ cultures of established cell lines, cell strains or primary cell cultures. Cell cultures are exposed to the test substance (liquid or solid) both with and without metabolic activation during about 1.5 normal cell cycle lengths. At least three analysable concentrations of the test substance should be used. At each concentration duplicate cultures should normally be used. At predetermined intervals after exposure of cell cultures to the test substance, the cells are treated with a metaphase-arresting substance, harvested, stained. Metaphase cells are analysed microscopically for the presence of chromosome aberrations.
    DOI: 10.1787/9789264071261-en
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  • 68
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    Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264071308
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 475; Essai d'aberration chromosomique sur moelle osseuse de mammifères
    Parallel Title: Parallelausg. Essai n 475: Essai d'aberration chromosomique sur moelle osseuse de mammifères
    Keywords: Environment
    Abstract: The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese hamsters). Structural chromosome aberrations may be of two types: chromosome or chromatid. Animals are exposed to the test substance (liquid or solid) by an appropriate route of exposure (usually by gavage using a stomach tube or a suitable intubation cannula, or by intraperitoneal injection) and are sacrificed at appropriate times after treatment. Prior to sacrifice, animals are treated with a metaphase-arresting agent. Chromosome preparations are then made from the bone marrow cells and stained, and metaphase cells are analysed for chromosome aberrations. Each treated and control group must include at least 5 analysable animals per sex. The limit dose is 2000 mg/kg/body weight/day for treatment up to 14 days, and 1000 mg/kg/body weight/day for treatment longer than 14 days.
    DOI: 10.1787/9789264071308-en
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  • 69
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    Economic Globalisation and the Environment (1997)
    Paris : OECD Publishing
    Details
    ISBN: 9789264174436
    Language: English
    Pages: Online-Ressource (90 p.) , ill.
    Keywords: Environment ; Economics
    Abstract: This book summarises the environmental implications of globalisation (both positive and negative) in terms of governance (the changing role of the nation-state and other institutions), competitiveness, foreign investments (pollution havens/industrial migration), sectoral economic activities (energy, transport, agriculture), technological change, and corporate environmental strategies.
    DOI: 10.1787/9789264174436-en
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  • 70
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    Test No. 305: Bioconcentration: Flow-through Fish Test (1996)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070462
    Language: English
    Pages: Online-Ressource (23 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 3
    Parallel Title: Parallelausg. Essai n 305; Bioconcentration; Essai dynamique chez le poisson
    Parallel Title: Parallelausg. Essai n 305: Bioconcentration: Essai dynamique chez le poisson
    Keywords: Environment
    Abstract: This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, under flow-through conditions (but semi-static regimes are permissible). The test consists of two phases: the exposure (uptake) and post-exposure (depuration) phases. During the uptake phase (28 days normally and 60 days maximum), separate groups of four fishes of one species are exposed to at least two concentrations of the test substance. They are then transferred to a medium free of the test substance for the depuration phase. A depuration phase is always necessary unless uptake of the substance during the uptake phase has been insignificant. In addition to the two test concentrations, a control group of fish is held without the test substance. The concentration of the test substance in/on the fish is followed through both phases of the test. During the test, dissolved oxygen, TOC, pH, total hardness and salinity, and temperature should be measured in vessels. The lipid content should be determined on the same biological material as is used to determine the concentration of the test substance, when feasible. Where possible the bioconcentration factor at apparent steady-state (BCF), expressed as a function of the total wet weight of the fish, and the kinetic bioconcentration factor (BCFK) are calculated. The bioconcentration should be expressed in relation to lipid content in addition to whole body weight.
    DOI: 10.1787/9789264070462-en
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  • 71
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    Test No. 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography (1996)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069848
    Language: English
    Pages: Online-Ressource (9 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 118; Détermination de la masse moléculaire moyenne en nombre et de la distribution des masses moléculaires des polymères par chromatographie sur gel perméable
    Parallel Title: Parallelausg. Essai n 118: Détermination de la masse moléculaire moyenne en nombre et de la distribution des masses moléculaires des polymères par chromatographie sur gel perméable
    Keywords: Environment
    Abstract: This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample is separated according to the hydrodynamic volumes of the individual constituents.According to their size, the eluted molecules can or not penetrate in the porous material (typically an organic gel) of which the columns are filled. Thus, the smallest molecules are retained whereas largest elute more quickly. At exit of column, detectors (generally by differential refractometry) provide the refractive index or UV-absorption and yield a simple distribution curve. However, to attribute actual molecular weight values to the curve, it is necessary to calibrate the column by passing down polymers of known molecular weight and, ideally, of broadly similar structure, e.g. various polystyrene standards. For each sample analyzed, two independent experiments must be undertaken. They have to be analysed individually. Mn, Mw, Mw/Mn must be provided for every measurement.
    DOI: 10.1787/9789264069848-en
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  • 72
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    Test No. 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography (1996)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069862
    Language: English
    Pages: Online-Ressource (9 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 119; Détermination de la teneur en polymères de faible masse moléculaire par chromatographie sur gel perméable
    Parallel Title: Parallelausg. Essai n 119: Détermination de la teneur en polymères de faible masse moléculaire par chromatographie sur gel perméable
    Keywords: Environment
    Abstract: This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample is separated according to the hydrodynamic volumes of the individual constituents. Low molecular weight is arbitrarily defined as a molecular weight below 1000 dalton.According to their size, the eluted molecules can or not penetrate in the porous material (typically an organic gel) of which the columns are filled. Thus, the smallest molecules are retained whereas largest elute more quickly. At exit of column, detectors (generally by differential refractometry) provide the refractive index or UV-absorption and yield a simple distribution curve. However, to attribute actual molecular weight values to the curve, it is necessary to calibrate the column by passing down polymers of known molecular weight and, ideally, of broadly similar structure, e.g. various polystyrene standards. For each sample analyzed, two independent experiments must be undertaken.
    DOI: 10.1787/9789264069862-en
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  • 73
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    OECD Economies at a Glance : Structural Indicators (1996)
    Paris : OECD Publishing
    Details
    ISBN: 9789264149472
    Language: English
    Pages: Online-Ressource (142 p)
    Parallel Title: Parallelausg. Coup d'oeil sur les économies de l'OCDE ; Indicateurs structurels
    Parallel Title: Parallelausg. Coup d'oeil sur les économies de l'OCDE : Indicateurs structurels
    Keywords: Environment
    Abstract: How many passenger cars are there per inhabitant in Spain? How can you become eligible for unemployment benefits in Canada? How did the total final consumption of energy evolve over the last few decades in OECD countries? How is privatisation of telecommunications firms progressing in various OECD countries? This publication answers these and many other questions concerning economic structure and policy in the OECD area, and its evolution over time, giving a broad set of valuable and reliable data in a range of areas -- labour markets, banking, regulation and competition, public finance and expenditures, social services, agriculture, energy, and environment, among others -- as well as some general indicators on basic living standards
    DOI: 10.1787/9789264149472-en
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  • 74
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    Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (1996)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070981
    Language: English
    Pages: Online-Ressource (14 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 422; Étude combinée de toxicité à doses répétées et de dépistage de la toxicité pour la reproduction et le développement
    Parallel Title: Parallelausg. Essai n 422: Étude combinée de toxicité à doses répétées et de dépistage de la toxicité pour la reproduction et le développement
    Keywords: Environment
    Abstract: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks; females should be dosed throughout the study (approximately 54 days). Normally, matings “one male to one female” should be used in this study. This Test Guideline is designed for use with the rat. It is recommended that the test substance be administered orally by gavage. This should be done in a single dose daily to the animals using a stomach tube or a suitable intubation cannula. Each group should be started with at least 10 animals of each sex. Generally, at least three test groups and a control group should be used. Dose levels should be selected taking into account any existing toxicity and (toxico-) kinetic data available. The limit test corresponds to one dose level of at least 1000 mg/kg body weight. The results of this study include measurements (weighing, food/water consumption) and daily detailed observations (including sensory reactivity to stimuli), preferably each day at the same time, as well as gross necropsy and histopathology. The findings of this toxicity study should be evaluated in terms of the observed effects, necropsy and microscopic findings. The evaluation will include the relationship between the dose of the test substance and the presence or absence of observations. Because of the short period of treatment of the male, the histopathology of the testis and epididymus must be considered along with the fertility data, when assessing male reproduction effects.
    DOI: 10.1787/9789264070981-en
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  • 75
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    Test No. 421: Reproduction/Developmental Toxicity Screening Test (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070967
    Language: English
    Pages: Online-Ressource (10 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 421; Essai de dépistage de la toxicité pour la reproduction et le développement
    Parallel Title: Parallelausg. Essai n 421: Essai de dépistage de la toxicité pour la reproduction et le développement
    Keywords: Environment
    Abstract: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed for use with the rat. It is recommended that each group be started with at least 10 animals of each sex. Generally, at least three test groups and a control group should be used. Dose levels may be based on information from acute toxicity tests or on results from repeated dose studies. The test substance is administered orally and daily. The limit test corresponds to one dose level of at least 1000 mg/kg body weight. The results of this study include measurements (weighing, food/water consumption) and daily and detailed observations, preferably each day at the same time, as well as gross necropsy and histopathology. The findings of this toxicity study should be evaluated in terms of the observed effects, necropsy and microscopic findings. Because of the short period of treatment of the male, the histopathology of the testis and epididymus must be considered along with the fertility data, when assessing male reproductive effects.
    DOI: 10.1787/9789264070967-en
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  • 76
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    Test No. 115: Surface Tension of Aqueous Solutions (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069787
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 115; Tension superficielle des solutions aqueuses
    Parallel Title: Parallelausg. Essai n 115: Tension superficielle des solutions aqueuses
    Keywords: Environment
    Abstract: This Test Guideline describes methods to determine the surface tension (in N/m) of aqueous solutions. The methods are based on the measurement of the force which it is necessary to exert vertically on a stirrup or ring, in contact with the surface of the liquid, in order to separate it from the surface, or on a plate, with an edge in contact with the surface, in order to draw up the film that has formed.There are four different methods: the plate method, the stirrup method, the ring method and the OECD harmonized ring method. They are described in detail in the ISO Standard 304-1985. The methods described are applicable to aqueous solutions of most substances regardless of their degree of purity. The concentration should be 90% of the saturation solubility, but must below 1g/l. This shall therefore be carried out under a protective cover to avoid interference at 20°C approximately. The ring is immersed below the surface of the solution. Then the table top, where the measurement vessel is placed, is lowered gradually and evenly at a rate of approximately 0.5 cm/min to detach the ring from the surface until the maximum force is reached. The force is read on the tensiometer. After completing the first measurement, measurements are repeated until a constant surface tension value is reached.
    DOI: 10.1787/9789264069787-en
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  • 77
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    Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070929
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 419; Neurotoxicité différée de substances organophosphorées; Étude à dose répétée sur 28 jours
    Parallel Title: Parallelausg. Essai n 419: Neurotoxicité différée de substances organophosphorées: Étude à dose répétée sur 28 jours
    Keywords: Environment
    Abstract: This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic laying hens (aged 8 to 12 months) for 28 days. The animals are observed at least daily until 14 days after the last dose. Biochemical measurements are undertaken on hens randomly selected from each group after the last dose. Two weeks after the last dose, the remainder of the hens are killed and histopathological examination is undertaken. The treatment group should contain at least 12 hens. Generally, at least three treatment groups should be used. The highest dose level should be chosen with the aim of inducing toxic effects; thereafter a descending sequence of dose levels should be selected. A limit test may be performed if no effects would be expected at a dose of 1000 mg/kg bw/d. The results of this study include weighing at least once a week, biochemistry (neuropathy target esterase, acetylcholinesterase) and, at least, and detailed observations, as well as gross necropsy and histopathology. The findings of this study should be evaluated in terms of the incidence, severity, and correlation of behavioral, biochemical and histopathological effects and any other observed effects in each of the treated and control groups.
    DOI: 10.1787/9789264070929-en
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  • 78
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    Test No. 102: Melting Point/ Melting Range (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069527
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 102; Point de fusion/Intervalle de fusion
    Parallel Title: Parallelausg. Essai n 102: Point de fusion/Intervalle de fusion
    Keywords: Environment
    Abstract: This Test Guidelines describes several methods and devices to determine the temperature or temperature range of the phase transition from the solid to the liquid state or from the liquid to the solid state. The melting point is defined as the temperature at which the phase transition from the solid to the liquid state at atmospheric pressure takes place. It is considerably affected by impurities. The selection of a particular method depends mainly on the state of physical aggregation of the sample and on whether or not the substance can be pulverized easily, with difficulty, or not at all. The methods are: the capillary/liquid bath, the capillary/metal block, the Kofler hot bar, the melt microscope, the differential thermal analysis and differential scanning calorimetry, the freezing temperature and the pour point.
    DOI: 10.1787/9789264069527-en
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  • 79
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    Test No. 109: Density of Liquids and Solids (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069664
    Language: English
    Pages: Online-Ressource (5 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 109; Densité des liquides et des solides
    Parallel Title: Parallelausg. Essai n 109: Densité des liquides et des solides
    Keywords: Environment
    Abstract: This Test Guideline lists methods for determining the density of liquids and solids, giving only a very succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in kg/m3. Several methods are for liquid substance only: hydrometer, immersed body method (both are buoyancy methods) and oscillating densitometer. These methods are applicable to liquids with a dynamic viscosity below 5 Pa s for hydrometer and oscillating densitometer and below 20 Pa s for immersed body method. The method for solids only is the air comparison pycnometer. The volume of a sample of the solid is measured in air or in an inert gas in a calibrated cylinder of variable volume. After concluding the volume measurement, the sample is weighed. The methods for liquids and solids are the hydrostatic balance (a buoyancy method) and the pycnometer. The dynamic viscosity of liquids to be investigated should not exceed 5 Pa s for hydrostatic balance, and should not be above 500 Pa s for pycnometer.
    DOI: 10.1787/9789264069664-en
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  • 80
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    Test No. 103: Boiling Point (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069541
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 103; Point d'ébullition
    Parallel Title: Parallelausg. Essai n 103: Point d'ébullition
    Keywords: Environment
    Abstract: This Test Guideline describes methods to determine the boiling point of test substances. The boiling point of a liquid is defined as the temperature (in K) at which the vapour pressure equals the standard atmospheric pressure 101.325 kPa.The influence of impurities on the boiling point depends greatly upon the nature of the impurity. The methods described in this Test Guideline can be applied to liquid and low-melting substances, provided that they do not undergo chemical change below the boiling point. The methods are: the ebulliometer, the dynamic method, the distillation method, the method according to Siwoloboff, the photocell detection, the differential thermal analysis, the differential scanning calorimetry. The photocell detection and thermal analysis permit the determination of boiling as well as melting temperatures. The dynamic method has the advantage that it can also be applied to the determination of the vapour pressure.
    DOI: 10.1787/9789264069541-en
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  • 81
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    Test No. 105: Water Solubility (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069589
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 105; Solubilité dans l'eau
    Parallel Title: Parallelausg. Essai n 105: Solubilité dans l'eau
    Keywords: Environment
    Abstract: This Test Guideline describes methods to determine the water solubility of test substances. The water solubility of a substance is the saturation mass concentration of the substance in water at a given temperature. This guideline addresses the determination of the solubility in water of essentially pure substances which are stable in water and not volatile. Before determining water solubility, it is useful to have some preliminary information on the substance, like structural formula, vapour pressure, dissociation constant and hydrolysis as a function of pH. The column elution method and the flask method which cover respectively solubilities below and above 10-2 g/l are described. The test is preferably run at 20 ± 0,5 °C. A simple preliminary test is allowed to determine approximately the appropriate amount of sample to be used in the final test, as well as the time necessary to achieve saturation.
    DOI: 10.1787/9789264069589-en
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  • 82
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    Test No. 418: Delayed Neurotoxicity of Organophosphorus Substances Following Acute Exposure (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264070905
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 418; Neurotoxicité différée de substances organophosphorées à la suite d'une exposiiton aigue͏̈
    Parallel Title: Parallelausg. Essai n 418: Neurotoxicité différée de substances organophosphorées à la suite d'une exposiiton aigue͏̈
    Keywords: Environment
    Abstract: The test substance is administered orally in a single dose to domestic hens. The animals are observed for 21 days, then the remainder of the hens are killed and histopathological examination is undertaken. The young adult domestic laying hen (Gallus gallus domesticus), aged 8 to 12 months, is recommended. The single dosing with the test substance should normally be by the oral route using gavage, gelatine capsules, or a comparable method. The treatment group should contain, at least 12 hens, and the positive control group at least 6 hens. The objective of the preliminary study is to maximize the main study dose. The limit test corresponds to one dose level of at least 2000 mg/kg body weight/day. The dose level of the main study should be high as possible taking into account the results of preliminary study and the maximum dose level (2000 mg/kg bw/d). The results of this study include measurements (weighing), biochemistry (neuropathy target esterase) and, at least, daily and detailed observations, as well as gross necropsy and histopathology. The findings of this study should be evaluated in terms of the incidence, severity, and correlation of behavioral, biochemical and histopathological effects and any other observed effects in the treated and control groups.
    DOI: 10.1787/9789264070905-en
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  • 83
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    Test No. 107: Partition Coefficient (n-octanol/water): Shake Flask Method (1995)
    Paris : OECD Publishing
    Details
    ISBN: 9789264069626
    Language: English
    Pages: Online-Ressource (4 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 107; Coefficient de partage (n-octanol/eau); méthode par agitation en flacon
    Parallel Title: Parallelausg. Essai n 107: Coefficient de partage (n-octanol/eau): méthode par agitation en flacon
    Keywords: Environment
    Abstract: This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio of the equilibrium concentrations of a dissolved substance in a two-phase system consisting of two largely immiscible solvents. The test should be done at a temperature in the range 20 to 25°C, kept constant at ± 1°. There are three runs with different volumes ratio of n-octanol to water. Duplicate vessels containing accurately measured amounts of the two solvents and stock solution are used in all three runs. After agitation the separation of the two phases, in general, is achieved by centrifugation. It is necessary to determine the concentrations of the test substance in both phases. Analytical methods which may be appropriate are: photometry, gas chromatography and high performance liquid chromatography. The total quantity of substance present in both phases should be calculated and compared with the quantity originally introduced. A Pow value is calculated from the data of each run. The six log Pow values should fall within a range of ± 0.3 units.
    DOI: 10.1787/9789264069626-en
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