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  • 2020-2022
  • 2010-2014  (27)
  • 1980-1984  (11)
  • 2010  (27)
  • 1981  (11)
  • Organisation for Economic Co-operation and Development  (38)
  • Australian Institute of Aboriginal Studies
  • Schweizerische Gesellschaft für Volkskunde
  • Environment  (38)
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  • 2020-2022
  • 2010-2014  (27)
  • 1980-1984  (11)
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  • 1
    Language: English
    Pages: 54 S.
    Additional Material: graph. Darst., Tab., Lit.Hinw.
    Edition: Online-Ausg. Online Ressource
    Series Statement: OECD green growth papers 2010, 01
    Series Statement: Industry and innovation
    Keywords: Informationstechnik ; Kommunikationstechnik ; Bedeutung ; Rolle ; Wirkung ; Auswirkung ; Klimaänderung ; Umwelt ; Ökologie ; Wirtschaftswachstum ; Umwelttechnik ; Produktion ; Branche ; Erwärmung ; Environment ; Science and Technology ; Amtsdruckschrift ; Arbeitspapier ; Graue Literatur
    Abstract: Information and communication technologies (ICTs) are a key enabler of “green growth” in all sectors of the economy. They are a key part of government strategies for a sustainable economic recovery. This report looks at how ICTs can improve their own environmental performance, and how they can be used to improve environmental performance throughout the economy and society. Direct environmental impacts of ICTs are considerable in areas such as energy use, materials throughput and end-of-life treatment. Government “green ICT” policies can be instrumental in promoting life-cycle approaches for improved R&D and design of ICT goods, services and systems. Innovative ICT applications enable sustainable production and consumption across the entire economy. The potential for improving environmental performance targets specific products, but also entire systems and industry sectors, e.g. construction, transport, energy.
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  • 2
    ISBN: 9789264090910
    Language: English
    Pages: Online-Ressource (29 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 233 ; Essai de toxicité sur le cycle de vie des chironomes dans un système eau-sédiment chargé ou eau chargée-sédiment
    Parallel Title: Parallelausg. Essai n 233 : Essai de toxicité sur le cycle de vie des chironomes dans un système eau-sédiment chargé ou eau chargée-sédiment
    Keywords: Environment
    Abstract: This Guideline is designed to assess the effects of prolonged exposure of chemicals to the life-cycle of the sediment-dwelling freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to five concentrations of the test chemical in sediment-water systems. The test substance is spiked into the water or alternatively the sediment, and first instar larvae are subsequently introduced into test beakers in which the sediment and water concentrations have been stabilised. Chironomid emergence, time to emergence, and sex ratio of the fully emerged and alive midges are assessed. Emerged adults are transferred to breeding cages, to facilitate swarming, mating and oviposition. The number of egg ropes produced and their fertility are assessed. From these egg ropes, first instar larvae of the 2nd generation are obtained. These larvae are placed into freshly prepared test beakers (spiking procedure as for the 1st generation) to determine the viability of the 2nd generation through an assessment of their emergence, time to emergence and the sex ratio of the fully emerged and alive midges. All data are analysed either by a regression model to estimate the concentration that would cause X% reduction in the relevant endpoint, or by using hypothesis testing to determine a No Observed Effect Concentration (NOEC).
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  • 3
    ISBN: 9789264088726
    Language: English
    Pages: Online-Ressource (428 p.)
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Advancing the aquaculture agenda
    Keywords: Aquakultur ; OECD-Staaten ; Agriculture and Food ; Environment ; Aquakultur ; Nachhaltigkeit ; Fischereipolitik
    Abstract: Aquaculture now provides more than 50% of the global supply of fisheries products for direct human consumption. This conference proceedings addresses key policy challenges of the aquaculture sector. Policy makers, academics, industry representatives, NGOs and international organisations gathered to discuss the critical economic, environmental and social aspects of aquaculture. This publication presents a selection of key issues covered by the workshop and includes a large number of country case studies, which provide specific examples of national approaches to aquaculture management.
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  • 4
    ISBN: 9789264087637
    Language: English
    Pages: Online-Ressource (252 p.) , ill.
    Parallel Title: Druckausg.
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment; (Chinese version)
    Parallel Title: Parallelausg. La fiscalité, l'innovation et l'environnement
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment: (Chinese version)
    Parallel Title: Erscheint auch als Taxation, innovation and the environment
    RVK:
    Keywords: Ökosteuer ; Treibhausgas-Emissionen ; Emissionshandel ; OECD-Staaten ; Environment ; Taxation ; Umweltabgabe ; Umweltschutz ; Innovation ; Umweltpolitik ; Umweltsteuer ; Innovationsförderung ; Internationaler Vergleich
    Abstract: Solving the world’s environmental problems could take a significant toll on economic growth if only today’s technologies are available. We know that innovation – the creation and adoption of new cleaner technologies and know-how – provides a means to achieve local and global environmental goals at significantly lower costs. Innovation is also a major driver of economic growth. OECD governments are increasingly using environmentally related taxes because they are typically one of the most effective policy tools available. Exploring the relationship between environmentally related taxation and innovation is critical to understanding the full impacts of this policy instrument as well as one potential facet of “green growth.” By putting a price on pollution, do environmentally related taxes spur innovation? What types of innovation result? Does the design of the tax play a critical role? What is the effect of this innovation? In analysing these questions, this report draws on case studies that cover Japan, Korea, Spain, Sweden, Switzerland, the United Kingdom, Israel and others. It covers a wide set of environmental issues and technologies, as well as the economic and policy contexts. The research methods range from econometric analysis to interviews with business owners and executives. The report also explores the use of environmentally related taxes in OECD countries and outlines considerations for policymakers when implementing these taxes. Green growth policies can stimulate economic growth while preventing environmental degradation, biodiversity loss and unsustainable natural resource use. The results from this publication will contribute to the Green Growth Strategy being developed by the OECD as a practical policy package for governments to harness the potential of greener growth.
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  • 5
    ISBN: 9789264077287
    Language: English
    Pages: Online-Ressource (210 p.) , ill.
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE; Luxembourg 2010
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE: Luxembourg 2010
    Keywords: Environment ; Luxembourg
    Abstract: OECD's 2010 review of Luxembourg's environmental conditions and progress in air, water, waste and materials management; nature and biodiversity; the environment-economy interface; the environment-social interface; and international commitments and co-operation. The analyses presented are supported by a broad range of economic and environmental data and include recommendations for further environmental and sustainable development progress.
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  • 6
    ISBN: 9789264090231
    Language: English
    Pages: Online-Ressource (116 p.) , ill.
    Parallel Title: Parallelausg. La transition vers une économie sobre en carbone ; objectifs publics et pratiques des entreprises
    Parallel Title: Parallelausg. La transition vers une économie sobre en carbone : objectifs publics et pratiques des entreprises
    Parallel Title: Erscheint auch als Transition to a low-carbon economy
    RVK:
    Keywords: Klimawandel ; Umweltmanagement ; OECD-Staaten ; Environment ; Finance and Investment ; Industry and Services ; OECD ; Umweltbezogenes Management ; Klimaänderung
    Abstract: Companies are increasingly aware of the need to address climate change. However, while many companies are taking action to address climate change, many others are still lagging behind. This report surveys responsible business practices addressing climate change and driving the shift to a low-carbon economy. It summarises policies, regulations and other instruments in support of a low carbon economy in OECD countries and emerging economies, and analyses corporate responses to these drivers. Using the principles of responsible business conduct identified in the OECD Guidelines for Multinational Enterprises, this report reviews three key areas of corporate action: accounting for greenhouse gas emissions; achieving emissions reductions; and engaging suppliers, consumers and other stakeholders.
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  • 7
    ISBN: 9789264090972
    Language: English
    Pages: Online-Ressource (16 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 442A ; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques; DA
    Parallel Title: Parallelausg. Essai n 442A : Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques: DA
    Keywords: Environment
    Abstract: The Local Lymph Node Assay: DA (LLNA: DA) is a non-radioactive modification to the LLNA method for identifying potential skin sensitizing test substances and measuring the proliferation of lymphocytes they induce in the auricular lymph nodes. The method, described in mouse (CBA/J strain), is based on measurement of the adenosine triphosphate (ATP) content by bioluminescence as an indicator of this proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent negative control group and, if appropriate, a positive control group. The experimental schedule is during 8 days. The time from animal sacrifice to measurement of ATP should not exceed 30 min. The procedure from excision of lymph nodes to ATP measurement should be kept uniform for each animal and completed within 20 minutes. The luciferin/luciferase method is applied to measure the bioluminescence in Relative Luminescence Units (RLU). This study includes: measurements (weighing, RLU), and clinical daily observations. The results are expressed as the Stimulation Index (SI) obtained by calculation. The SI should be ¡Ý1.8 before further evaluation of the test material as a potential skin sensitizer is warranted.
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  • 8
    ISBN: 9789264071100
    Language: English
    Pages: Online-Ressource (20 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 429; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques
    Parallel Title: Parallelausg. Essai n 429: Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques
    Keywords: Environment
    Abstract: The basic principle underlying the Local Lymph Node Assay (LLNA) in mouse is that sensitizers induce a primary proliferation of lymphocytes in the auricular lymph nodes draining the site of chemical application. This proliferation is proportional to the dose applied and provides a measurement of sensitisation. The method described is based on the use of radioactive labelling to measure cell proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a negative control group treated with the vehicle only, and a positive control, as appropriate. The experimental schedule of the assay is during 6 days. Thereafter, the animals are killed and a cell suspension of lymph node cells is prepared. The incorporation of 3H-methyl thymidine is measured by ¦Â-scintillation counting as disintegrations per minute (DPM). The Test Guideline includes performance standards that can be used to evaluate the validation status of new and/or modified test methods that are functionally and mechanistically similar to the LLNA. A reduced LLNA approach which could use up to 40% fewer animals is also described as an option. This study includes: measurements (weighing, DPM), and clinical daily observations. Results are expressed as the Stimulation Index (SI).The SI is obtained by calculation and should be ¡Ý3 before classification of the test material as a skin sensitizer is warranted.
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  • 9
    ISBN: 9789264090897
    Language: English
    Pages: Online-Ressource (25 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 223 ; Oiseaux, essai de toxicité orale aigue͏̈
    Parallel Title: Parallelausg. Essai n 223 : Oiseaux, essai de toxicité orale aigue͏̈
    Keywords: Environment
    Abstract: This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only options are sequential testing procedures. The test method selected will depend on whether or not a definitive median dose (LD50) and slope of the dose-response curve are both needed. The limit dose test is the preferred test when toxicity is expected to be low and lethality is unlikely at the limit dose. The limit dose should be adequate for assessment purposes, and it is usually 2000 mg/kg-bwt. Five or ten birds are tested at the limit dose in addition to a control group. The LD50-slope test is the preferred test when regulatory or other requirements determine that the slope of the dose-response curve and/or the confidence interval is required in addition to an estimate of the LD50. This is a 3- or 4-stage test with 24 or 34 birds in addition to a control group. The LD50-only test is the preferred test when regulatory or other requirements determine that only the median lethal dose is required but neither the slope of the dose response curve or the confidence interval for the LD50 is required. This may be the appropriate test to estimate a percentile of a species sensitivity distribution of LD50s and to provide information for product labelling purposes. This test has two stages, with 14 birds in addition to a control group. Software to be used with TG 223. Click here. Software not part of the Mutual Acceptance of Data.
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  • 10
    ISBN: 9789264070080
    Language: English
    Pages: Online-Ressource (18 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 2
    Parallel Title: Parallelausg. Essai n 209; Boue activée, essai d'inhibition de la respiration (oxydation du carbone et de l'ammonium)
    Parallel Title: Parallelausg. Essai n 209: Boue activée, essai d'inhibition de la respiration (oxydation du carbone et de l'ammonium)
    Keywords: Environment
    Abstract: This Test Guideline is designed to assess the effects of a substance on micro-organisms from activated sludge of waste-water treatment plants by measuring their respiration rate (carbon and/or ammonium oxidation) as oxygen consumption. The test results may also serve as an indicator of suitable non-inhibitory concentrations of test substances to be used in biodegradability tests. The test allows the determination of ECx and/or NOEC values of the test substance. The inhibition of three different oxygen uptakes may be determined, i.e. total, heterotrophic only, and that due to nitrification in the absence and presence of N-allylthiourea, a specific nitrification inhibitor. For obtaining both NOEC and ECx, six controls and five treatment concentrations in a geometric series with five replicates are recommended. In each test vessel, test mixtures containing water, synthetic sewage feed and the test substance are incubated at the pH of 7.5 ±0.5 and the temperature within 20±2°C under forced aeration to keep the dissolved oxygen concentration above 60-70% saturation. The oxygen consumption is measured after 3 hours of exposure and additional measurements at 30 minutes of exposure can be performed in the case that the test substance is rapidly degraded.
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  • 11
    ISBN: 9789264090279
    Language: English
    Pages: Online-Ressource (196 p.)
    Parallel Title: Druckausg.
    Parallel Title: Parallelausg. Payer pour la biodiversité ; Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Parallel Title: Parallelausg. Paying for Biodiversity; Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Parallel Title: Parallelausg. Payer pour la biodiversité : Améliorer l'efficacité-coût des paiements pour services écosystémiques
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Bulgarian version)
    Parallel Title: Parallelausg. Paying for Biodiversity: Enhancing the Cost-Effectiveness of Payments for Ecosystem Services (Romanian version)
    Parallel Title: Erscheint auch als Karousakis, Katia Paying for biodiversity
    RVK:
    Keywords: Artenvielfalt ; Umwelt ; Umweltökonomik ; Umweltpolitik ; Kosten-Wirksamkeits-Analyse ; Environment ; Biodiversität ; Umweltpolitik ; Umweltökonomie
    Abstract: Biodiversity and ecosystem services provide tangible benefits for society, such as food provisioning, water purification, genetic resources or climate regulation. These services provide critical life support functions and contribute to human health, well being and economic growth. Yet biodiversity is declining worldwide and, in some areas, this loss is accelerating. The need for policies that promote the conservation and sustainable use of biodiversity and ecosystem services is more important than ever. Payments for Ecosystem Services (PES) is a direct and flexible incentive-based mechanism under which the user or beneficiary of an ecosystem service makes a direct payment to an individual or community whose land use decisions have an impact on the ecosystem service provision. Interest in PES has been increasing rapidly over the past decade: PES are proliferating worldwide and there are already more than 300 programmes in place today at national, regional and local levels. Drawing on the literature concerning effective PES and on more than 30 case studies from both developed and developing countries, this book aims to identify good practice in the design and implementation of PES programmes so as to enhance their environmental and cost effectiveness. It addresses the following questions: Why are PES useful and how do they work? How can they be made most effective environmentally and how can their cost-effectiveness be maximised? What are the different potential sources of finance for PES programmes, and how can they be secured? and What are the lessons learned from existing PES programmes and insights for future programmes, including international PES?
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  • 12
    ISBN: 9789264095434
    Language: English
    Pages: Online-Ressource (324 p.)
    Series Statement: Harmonisation of Regulatory Oversight in Biotechnology
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Safety assessment of transgenic organisms ; Vol. 3
    RVK:
    Keywords: Agriculture and Food ; Environment ; Science and Technology ; Transgene Pflanzen ; Umweltgefährdung ; Risikoanalyse
    Abstract: The books on “Safety Assessment of Transgenic Organisms” constitute a compilation of the OECD Biosafety Consensus Documents. When published, Volume 1 and 2 contained the documents issued before 2006; Volume 3 and 4 are a continuation of the compilation up to 2010. The OECD Biosafety Consensus Documents identify elements of scientific information used in the environmental safety and risk assessment of transgenic organisms which are common to OECD member countries and some non members associated with the work. This is intended to encourage information sharing, promote harmonised practices, and prevent duplication of effort among countries. These books offer ready access to those consensus documents which have been issued on the website thus far. As such, it should be of value to applicants for commercial uses of transgenic organisms (crops, trees, microorganisms), to regulators and risk assessors in national authorities, as well as the wider scientific community. More information on the OECD's work related to the biosafety of transgenic organisms is found at BioTrack Online (http://www.oecd.org/biotrack).
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  • 13
    ISBN: 9789264087873
    Language: English
    Pages: Online-Ressource (196 p.)
    Series Statement: OECD Environmental Performance Reviews
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE; Japon 2010
    Parallel Title: Parallelausg. Examens environnementaux de l'OCDE: Japon 2010
    Keywords: Environment ; Japan
    Abstract: This 2010 review of Japan's environmental conditions and policies evaluates progress in reducing the pollution burden, improving natural resource management, integrating environmental and economic policies, and strengthening international co-operation. It includes coverage of policy for greening growth, implementation of environmental policies, climate change, waste management and the 3Rs (reduce, reuse, recycle), and nature and biodiversity. The review finds that since the last review, Japan has made steady progress in addressing a range of environmental issues, notably air and water pollution, and the management of chemicals and waste. The energy intensity of the economy has continued to decrease, particularly in the industrial sector, and is among the lowest in OECD countries. Material intensity has also decreased. At the same time, several more complex, long-term challenges have come to the fore: climate change, sound waste, materials management, and biodiversity conservation. Much of the last decade was characterised by sluggish economic growth, and environment and green innovation are targeted as key drivers of future growth and job creation in Japan's New Growth Strategy.
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  • 14
    ISBN: 9789264077225
    Language: English
    Pages: Online-Ressource (278 p.)
    Parallel Title: Parallelausg. L'éco-innovation dans l'industrie ; favoriser la croissance verte
    Parallel Title: Parallelausg. L'éco-innovation dans l'industrie : favoriser la croissance verte
    Parallel Title: Erscheint auch als Eco-innovation in industry
    RVK:
    RVK:
    Keywords: Industrie ; Innovationsmanagement ; Umwelttechnik ; OECD-Staaten ; Environment ; Science and Technology ; Industry and Services ; Industrie ; Nachhaltigkeit ; OECD
    Abstract: Eco-innovation will be a key driver of industry efforts to tackle climate change and realise “green growth” in the post-Kyoto era. Eco-innovation calls for faster introduction of breakthrough technologies and for more systemic application of available solutions, including non-technological ones. It also offers opportunities to involve new players, develop new industries and increase competitiveness. Structural change in economies will be imperative in coming decades. This book presents the research and analysis carried out during the first phase of the OECD Project on Sustainable Manufacturing and Eco-innovation. Its aim is to provide benchmarking tools on sustainable manufacturing and to spur eco-innovation through better understanding of innovation mechanisms. It reviews the concepts and forms an analytical framework; analyses the nature and processes of eco-innovation; discusses existing sustainable manufacturing indicators; examines methodologies for measuring eco-innovation; and takes stock of national strategies and policy initiatives for eco-innovation.
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  • 15
    Language: English
    Pages: 54 p. , 21 x 29.7cm
    Series Statement: OECD Environment Working Papers no.13
    Keywords: Environment
    Abstract: Debates exist between those who claim that environmental policy will impose additional burdens and costs on industries, thus impairing their competitiveness, and those who claim that improved environmental performance can spur competitiveness. These arguments often surface when new environmental policy regulation are considered, e.g. when the REACH Directive was introduced in Europe, or when a government is considering the introduction of a carbon tax. The report develops a conceptual framework to shed some light on this difficult debate. Competitiveness impacts of environmental policies may derive from the policy itself, or from the improvements of the environmental performance that derives from the policy. These impacts can be analysed at either firm or industry levels; they may differ over the short and long term. Globalisation, with the increasing role of MNEs and mobile capital and labour, is adding more complexity. This framework is used to decipher some of the messages that come out of empirical studies on these issues. Empirical evidence is mixed, and the paper identifies methodological and substantive reasons why empirical research fails to determine the relationship between environmental policy and competitiveness. Lessons derive from this literature review. Typically, even when implementing the environmental policy is clearly in the overall interest of society, the costs and benefits of the policy are unlikely to be equally shared among economic agents. While some win, individual firms or industries may stand to lose. Policy design should make sure that the adverse competitiveness impacts are not unnecessarily large, for example by paying attention to predictability, transition periods, and transaction costs. Specific measures to support the losers in their adjustment can also be developed. Sometimes measures to mitigate the adverse competitiveness impacts of an environmental policy are necessary to achieve political support for the policy. In those instances, the planned measures should be carefully analysed from several angles to ensure that they do not inadvertently hurt the efficiency and effectiveness of the original policy. More work is required to further explore these issues, which are consequential for the design, the implementation and the enforcement of environmental policies.
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  • 16
    ISBN: 9789264091016
    Language: English
    Pages: Online-Ressource (23 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 487 ; Essai in vitro de micronoyaux sur cellules de mammifères
    Parallel Title: Parallelausg. Essai n 487 : Essai in vitro de micronoyaux sur cellules de mammifères
    Keywords: Environment
    Abstract: The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells. Micronuclei may originate from acentric chromosome fragments (i.e. lacking a centromere), or whole chromosomes that are unable to migrate to the poles during the anaphase stage of cell division. The assay detects the activity of clastogenic and aneugenic test substances in cells that have undergone cell division during or after exposure to the test substance. This Test Guideline allows the use of protocols with and without the actin polymerisation inhibitor cytochalasin B. Cytochalasin B allows for the identification and selective analysis of micronucleus frequency in cells that have completed one mitosis, because such cells are binucleate. This Test Guideline also allows the use of protocols without cytokinesis block provided there is evidence that the cell population analysed has undergone mitosis.
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  • 17
    ISBN: 9789264086913
    Language: English
    Pages: Online-Ressource (32 p.)
    Parallel Title: Parallelausg. Document d'orientation pour les études d'impact sur la durabilité
    Keywords: Environment ; Social Issues/Migration/Health ; Economics
    Abstract: This publication offers a general introduction to sustainability impact assessment, which is an approach for exploring the combined economic, environmental and social impacts of a range of proposed policies, programmes, strategies and action plans. Such assessments can also assist decision-making and strategic planning throughout the entire policy cycles. It is not an in-depth or detailed user manual, but rather outlines basic principles and process steps of sustainability impact assessments, drawing on examples from Switzerland, Belgium and the European Commission, among others. This publication is a valuable source of information for policy makers on sustainability impact assessments.
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  • 18
    Online Resource
    Online Resource
    Paris : OECD Publishing
    ISBN: 9789264070882
    Language: English
    Pages: Online-Ressource (20 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 417; Toxicocinétique
    Parallel Title: Parallelausg. Essai n 417: Toxicocinétique
    Keywords: Environment
    Abstract: This Test Guideline describes in vivo studies that provide information on mass balance, absorption, bioavailability, tissue distribution, metabolism, excretion, and basic toxicokinetic parameters [e.g. AUC], as well as supplemental approaches that may provide useful information on toxicokinetics. Information from toxicokinetic studies helps to relate concentration or dose to the observed toxicity and to understand its mechanism of toxicity. The test substance ("unlabelled" or "radiolabelled" forms) is normally administered by an oral route, but other routes of administration may be applicable. Single dose administration of the substance (preferably a minimum of two dose levels) may be adequate, but repeated dose may be needed in some circumstances. Toxicokinetic studies should preferably be carried out in the same species as that used in other toxicological studies performed with the substance (normally the rat, a minimum of 4 animals of one sex for each dose). Initial estimation of absorption can be achieved by mass balance determination, but further investigations such as intravenous (IV) administration and biliary excretion studies might be necessary. Bioavailability can be determined from plasma/blood kinetics of oral and IV groups. The percent of the total dose in tissues should at a minimum be measured at the termination of experiment,but additional time points may also be needed. Metabolites present at 5 % or greater of the administered dose should be identified. The rate and extent of excretion of the administered dose should be determined by measuring the percent recovered dose from urine, faeces and expired air.
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  • 19
    ISBN: 9789264085930
    Language: English
    Pages: Online-Ressource (46 p)
    Parallel Title: Parallelausg. Réduire les coûts de gestion des produits chimiques ; Comment l'OCDE aide les gouvernements et l'industrie
    Parallel Title: Parallelausg. Réduire les coûts de gestion des produits chimiques : Comment l'OCDE aide les gouvernements et l'industrie
    Keywords: Environment ; Governance ; Industry and Services
    Abstract: The chemicals industry - including industrial chemicals, pharmaceuticals, pesticides, food and feed additives and cosmetics - is one of the world’s largest industrial sectors. Many chemical products are traded internationally. Varying national requirements can mean duplication of efforts and significant costs for the chemicals industry, as well as posing barriers to trade. By agreeing on test methods and data quality and sharing the workload of chemical safety testing and assessments, countries together achieve environmentally sustainable and cost-effective results. For non-clinical health and safety testing, for example, the results of such studies carried out on a chemical product in one OECD country must be accepted by the others as long as it was carried out in accordance with the OECD Test Guidelines and Principles of Good Laboratory Practice. This saves the chemicals industry the expense of duplicative testing for products that are marketed in more than one country. This report analyses the rigorous and comprehensive system for assessing and managing chemicals that helps governments and industry save about EUR 150 million each year, through “work sharing” facilitated by the OECD.
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  • 20
    ISBN: 9787511103338
    Language: Chinese
    Pages: Online-Ressource (227 p.) , ill.
    Parallel Title: Parallelausg. Ensuring Environmental Compliance; Trends and Good Practices
    Parallel Title: Parallelausg. Faire respecter les normes environnementales ; Tendances et bonnes pratiques
    Parallel Title: Parallelausg. Ensuring Environmental Compliance: Trends and Good Practices
    Parallel Title: Parallelausg. Faire respecter les normes environnementales : Tendances et bonnes pratiques
    Keywords: Environment ; Governance
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  • 21
    Online Resource
    Online Resource
    Paris : OECD Publishing
    ISBN: 9789264091375
    Language: English
    Pages: Online-Ressource (276 p.) , ill.
    Parallel Title: Erscheint auch als Cities and climate change
    RVK:
    RVK:
    RVK:
    RVK:
    Keywords: Klimawandel ; Stadt ; Kommunalpolitik ; Kommunalverwaltung ; OECD-Staaten ; Klima ; Environment ; Governance ; Urban, Rural and Regional Development ; Klima ; Klimakatastrophe ; Klimaveränderung ; Klimawandel ; Stadt ; Klimaänderung
    Abstract: As the hubs of economic activity, cities drive the vast majority of the world’s energy use and are major contributors to global greenhouse gas emissions. Because they are home to major infrastructure and highly concentrated populations, cities are also vulnerable to the impacts of climate change, such as rising sea levels, warmer temperatures and fiercer storms. At the same time, better urban planning and policies can reduce energy use and greenhouse gas emissions and improve the resilience of urban infrastructure to climate change, thus shaping future trends. This book shows how city and metropolitan regional governments working in tandem with national governments can change the way we think about responding to climate change. The chapters analyse: trends in urbanisation, economic growth, energy use and climate change; the economic benefits of climate action; the role of urban policies in reducing energy demand, improving resilience to climate change and complementing global climate policies; frameworks for multilevel governance of climate change including engagement with relevant stakeholders; and the contribution of cities to “green growth”, including the “greening” of fiscal policies, innovation and jobs. The book also explores policy tools and best practices from both OECD and some non-member countries. Cities and Climate Change reveals the importance of addressing climate change across all levels of government. Local involvement through “climate-conscious” urban planning and management can help achieve national climate goals and minimise tradeoffs between environmental and economic priorities at local levels. The book will be relevant to policy makers, researchers, and others with an interest in learning more about urbanisation and climate change policy.
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  • 22
    ISBN: 9789264090958
    Language: English
    Pages: Online-Ressource (18 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 439 ; Irritation cutanée in vitro ; Essai sur épiderme humain reconstitué
    Parallel Title: Parallelausg. Essai n 439 : Irritation cutanée in vitro : Essai sur épiderme humain reconstitué
    Keywords: Environment
    Abstract: This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2. It is based on reconstructed human epidermis (RhE), which in its overall design closely mimics the biochemical and physiological properties of the upper parts of the human skin. Cell viability is measured by enzymatic conversion of the vital dye MTT into a blue formazan salt that is quantitatively measured after extraction from tissues. Irritant test substances are identified by their ability to decrease cell viability below defined threshold levels (below or equal to 50% for UN GHS Category 2). This Test Guideline also includes a set of Performance Standards for the assessment of similar and modified RhE-based test methods. There are three validated test methods that adhere to this Test Guideline. Depending on the regulatory framework and the classification system in use, this procedure may be used to determine the skin irritancy of test substances as a stand-alone replacement test for in vivo skin irritation testing, or as a partial replacement test, within a tiered testing strategy.
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  • 23
    ISBN: 9789264088320
    Language: Spanish
    Pages: Online-Ressource (212 p.)
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation; Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement ; Document d'orientation
    Parallel Title: Parallelausg. Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento; Guia para o Desenvolvimento de Políticas
    Parallel Title: Parallelausg. Integrating Climate Change Adaptation into Development Co-operation: Policy Guidance
    Parallel Title: Parallelausg. Adaptation au changement climatique et coopération pour le développement : Document d'orientation
    Parallel Title: Parallelausg. Integração da Adaptação às Alterações Climáticas na Cooperação para o Desenvolvimento: Guia para o Desenvolvimento de Políticas
    Keywords: Environment ; Development
    Abstract: El cambio climático es una amenaza seria y a largo plazo que puede afectar a cualquier parte del mundo. Su impacto negativo golpeará a los países pobres y a las capas de población más desfavorecidas de manera desproporcionada, complicando aún más el logro de sus objetivos de desarrollo. La guía Integración de la Adaptación en la Cooperación para el Desarrollo ofrece información esencial y consejos sobre cómo facilitar la integración de la adaptación al cambio climático en los procesos de desarrollo. Los objetivos de esta guía son los siguientes: i) facilitar la comprensión de las implicaciones del cambio climático en la práctica del desarrollo y promover la necesidad asociada de integrar la adaptación al cambio climático en las políticas y prácticas de desarrollo tanto de los organismos de cooperación como de los países socios, ii) identificar los enfoques más adecuados para integrar la adaptación al cambio climático en las políticas de desarrollo a nivel nacional, sectorial y de proyecto, tanto en zonas urbanas como en zonas rurales, y iii) determinar modalidades prácticas para que los donantes apoyen a los países socios en sus esfuerzos para reducir su vulnerabilidad a la variabilidad climática y el cambio climático. Aunque los esfuerzos por integrar la adaptación al cambio climático ha de ser dirigido por los países socios, los donantes internacionales tienen un papel crítico que desempeñar en el apoyo a esos esfuerzos. Esta guía para la orientación de políticas está destinada especialmente a responsables políticos, a profesionales de organismos de cooperación al desarrollo y sus contrapartes en los gobiernos de los países, y a otras partes interesadas, tales como organizaciones no gubernamentales.
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  • 24
    ISBN: 9789264090996
    Language: English
    Pages: Online-Ressource (15 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 442B ; Sensibilisation cutanée ; Essai de stimulation locale des ganglions lymphatiques; BrdU- ELISA
    Parallel Title: Parallelausg. Essai n 442B : Sensibilisation cutanée : Essai de stimulation locale des ganglions lymphatiques: BrdU- ELISA
    Keywords: Environment
    Abstract: The Local Lymph Node Assay: BrdU-ELISA (LLNA:BrdU-ELISA) is a non-radioactive modification to the LLNA method for identifying potential skin sensitizing test substances and measuring the proliferation of lymphocytes they induce in the auricular lymph nodes. The method described in mouse is based on the use of measuring 5-bromo-2-deoxyuridine (BrdU) content, an analogue of thymidine, as an indicator of this proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent negative control group and a positive control group. The experimental schedule is during 6 days. Thereafter, the animals are killed and a single cell suspension of lymph node cells (LNC) is prepared. The procedure for preparing the LNC is crucial, in particular for the small lymph nodes in NC animals. Then the BrdU content in DNA of lymphocytes is measured by ELISA using a commercial kit of by Flow Cytometry (FCM). This study includes: measurements (weighing, BrdU) and clinical daily observations. The results are expressed as the Stimulation Index (SI) obtained by calculation from the mean BrdU labelling index. The SI should be ≥1.6 for the ELISA method or ≥2.7 for the FCM method for identifying the test material as a potential skin sensitizer.
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  • 25
    ISBN: 9789264090934
    Language: English
    Pages: Online-Ressource (30 p)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 3
    Parallel Title: Parallelausg. Essai n 317 ; Bioaccumulation chez les oligochètes terrestres
    Parallel Title: Parallelausg. Essai n 317 : Bioaccumulation chez les oligochètes terrestres
    Keywords: Environment
    Abstract: This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant (ks) and the elimination rate constant (ke). The test consists of two phases: the uptake (exposure) phase and the elimination (post-exposure) phase. An elimination phase is always required unless uptake of the test substance during the exposure phase has been insignificant. The test organisms are exposed to the test substance during the uptake phase. The test substance is incorporated into the soil; it is recommended to use the artificial soil described in the OECD Test Guideline 207 (Earthworm, acute toxicity test). The uptake phase should be of 14 days (enchytraeids) or 21 days (earthworms) unless it is demonstrated that steady state has been reached. For the elimination phase, the worms are transferred to a soil free of test substance. The elimination phase is generally of 21 days.
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  • 26
    Online Resource
    Online Resource
    Beijing : Chinese Academy of Governance, China
    ISBN: 9787515000718
    Language: Chinese
    Pages: Online-Ressource (302 p.) , ill.
    Parallel Title: Parallelausg. Taxation, Innovation and the Environment
    Parallel Title: Parallelausg. La fiscalité, l'innovation et l'environnement
    Keywords: Environment ; Taxation
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  • 27
    ISBN: 9789264096158
    Language: English
    Pages: Online-Ressource (336 p.)
    Series Statement: Harmonisation of Regulatory Oversight in Biotechnology
    Parallel Title: Druckausg.
    Parallel Title: Erscheint auch als Safety assessment of transgenic organisms ; Vol. 4
    RVK:
    Keywords: Agriculture and Food ; Environment ; Science and Technology ; Transgene Pflanzen ; Umweltgefährdung ; Risikoanalyse
    Abstract: The books on “Safety Assessment of Transgenic Organisms” constitute a compilation of the OECD Biosafety Consensus Documents. When published, Volume 1 and 2 contained the documents issued before 2006; Volume 3 and 4 are a continuation of the compilation up to 2010. The OECD Biosafety Consensus Documents identify elements of scientific information used in the environmental safety and risk assessment of transgenic organisms which are common to OECD member countries and some non members associated with the work. This is intended to encourage information sharing, promote harmonised practices, and prevent duplication of effort among countries. These books offer ready access to those consensus documents which have been issued on the website thus far. As such, it should be of value to applicants for commercial uses of transgenic organisms (crops, trees, microorganisms), to regulators and risk assessors in national authorities, as well as the wider scientific community. More information on the OECD's work related to the biosafety of transgenic organisms is found at BioTrack Online (http://www.oecd.org/biotrack).
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  • 28
    ISBN: 9789264069725
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 112; Constante de dissociation dans l'eau
    Parallel Title: Parallelausg. Essai n 112: Constante de dissociation dans l'eau
    Keywords: Environment
    Abstract: This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation constant requires a measure of the concentrations of the dissociated and undissociated forms of the chemical substance. From a knowledge of the stoichiometry of the dissociation reaction the appropriate constant can be determined. In the particular case described in this Guideline the substance is behaving as an acid or a base, and the determination is most conveniently done by determining the relative concentrations of ionised and unionised forms of the substance and the pH of the solution. The relationship between these terms is given in the equation for pKa. Some compounds exhibit more than one dissociation constant. Some of the methods described are also suitable for non-acid/base dissociation. There are two basic approaches to the determination of pKa. One involves titrating a known amount of substance with standard acid or base, as appropriate; the other involves determining the relative concentrations of the ionised and unionised forms and their pH dependence. Methods based on those principles may be classified as titration, spectrophotometric and conductometric procedures.
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  • 29
    Online Resource
    Online Resource
    Paris : OECD Publishing
    ISBN: 9789264069763
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 114; Viscosité des liquides
    Parallel Title: Parallelausg. Essai n 114: Viscosité des liquides
    Keywords: Environment
    Abstract: This Test Guideline describes methods to measure the viscosity of liquids. The methods listed are appropriate in principle for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is only possible with the rotational viscometer. Viscosity measurements are carried out predominantly according to five methods: the capillary viscometer, the flow cup, the rotational viscometer, the rolling ball viscometer and the drawing ball viscometer. Each determination of viscosity should preferably be made at a temperature of 20°C and at one other temperature approximately 20°C higher. At least two determinations should be made at each temperature. The evaluation of the viscosity measurement is to be carried out according to the standards in the case of capillary and forced ball viscometers. In the case of rotational viscometers, the specification of a viscosity is appropriate only for Newtonian fluids. For non- Newtonian fluids the results obtained are preferred in the form of flow curves which must be interpreted, assuming the validity of various laws of flow.
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  • 30
    ISBN: 9789264069800
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 116; Liposolubilité des substances solides et liquides
    Parallel Title: Parallelausg. Essai n 116: Liposolubilité des substances solides et liquides
    Keywords: Environment
    Abstract: This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method can only be applied to pure substances, non-reactive with triglyceride, which are stable at 50°C for at least 24 hours and which also are not appreciably volatile under the same conditions. The substance is dissolved in a liquid "standard fat" by stirring, and the saturation mass fraction of the substance is achieved by continued addition until a constant value for the mass fraction dependent variable is achieved as determined by a suitable analytical method.The methods use eight samples; each should be twice the quantity necessary for saturation as determined in the preliminary test. After adding a weighed amount of approximately 25 g of liquified and mixed standard fat, four flasks are stirred at 30°C (group I) and the other four at approximately 50°C (group II), each for at least one hour. All the flasks are stirred at 37°C, for liquids during 3 hours for two flasks of each group and for at least 24 hours for the last two flasks. At the end a sample is taken, weighed and the mass fraction is determined with different methods (photometric methods, gas chromatography, and extraction).
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  • 31
    ISBN: 9789264070769
    Language: English
    Pages: Online-Ressource (9 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 411; Toxicité cutanée subchronique; 90 jours
    Parallel Title: Parallelausg. Essai n 411: Toxicité cutanée subchronique: 90 jours
    Keywords: Environment
    Abstract: This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit test. This Test Guideline is intended for use with the adult rat, rabbit or guinea pig. At least 20 animals (10 female and 10 male) with healthy skin should be used at each dose level (at least three). The highest dose level should result in toxic effects but not produce an incidence of fatalities. The limit test corresponds to one dose level of at least 1000 mg/kg body weight. The method is based on the repeated application of the substance of interest during one limited period (several hours daily during 90 days). The test substance should be applied over not less than 10 per cent of the body surface area. The results of this study include: measurements and daily and detailed observations (ophthalmological examination, haematology, clinical biochemistry and urinalysis), as well as gross necropsy and histopathology. A properly conducted subchronic test should provide a satisfactory estimation of a non effect level.
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  • 32
    ISBN: 9789264070448
    Language: English
    Pages: Online-Ressource (11 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 3
    Parallel Title: Parallelausg. Essai n 304A; Biodégradabilité intrinsèque dans le sol
    Parallel Title: Parallelausg. Essai n 304A: Biodégradabilité intrinsèque dans le sol
    Keywords: Environment
    Abstract: The method described in this Test Guideline is designed for the evaluation of the mineralisation rate of a 14C-labelled compound in soil. The method is applicable to volatile or non-volatile, soluble or insoluble compounds which are not inhibitory to micro-organisms. The basic test consists on the treatment of a small sample of soil (50g) with the 14C-labelled test chemical (100µl) in a biometer flask apparatus. The soil and the radioactive test solution are mixed. In addition, an equivalent volume of test solution is placed in a 100 ml volumetric flask for direct determination of the added radioactivity. The biometer flask is closed with a stopper through which an Ascarite filter is inserted. The unit is charged by injecting 10 ml of alkali solution into the side tube. Experiment duration times of 1, 2, 4, 8, 16, 32 and - if necessary - 64 days should be chosen for measurement. The test requires parallel determinations. The method can included optional experiments: for chemicals of a vapour pressure higher than 0.0133 Pa and for relatively persistent chemicals. Release of 14CO2 from the test chemical is measured by means of alkali absorption and liquid scintillation counting. The 14CO2 radioactivity recovered is plotted versus time. Incubation time is sufficient when a total of 50 per cent CO2 expressed as 14C originally applied can be measured. Incubation should be stopped after reaching 64 days, whether or not this value is obtained.
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  • 33
    ISBN: 9789264070363
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 3
    Parallel Title: Parallelausg. Essai n 302A; Biodégradabilité dite intrinsèque; Méthode SCAS modifiée
    Parallel Title: Parallelausg. Essai n 302A: Biodégradabilité dite intrinsèque: Méthode SCAS modifiée
    Keywords: Environment
    Abstract: This Test Guideline describes a method which is an adaptation of the Soap and Detergent Association semi-continuous activated sludge (SCAS) procedure for assessing the primary biodegradation of alkyl benzene sulphonate. The test does not simulate those conditions experienced in a sewage treatment plant. Activated sludge from a sewage treatment plant is placed in an aeration (SCAS) unit. The test compound (non-volatile, water soluble, organic, non-inhibitoring to bacteria at the test concentration) and settled domestic sewage are added, and the mixture is aerated for 23 hours. The aeration is then stopped, the sludge allowed to settle and the supernatant liquor is removed. The sludge remaining in the aeration chamber is then mixed with a further aliquot of test compound and sewage and the cycle is repeated. The above fill and draw procedure is repeated daily throughout the test. A high concentration of aerobic micro-organisms is used. The length of the test for compounds showing little or no biodegradation is indeterminate, but experience suggests that this should be at least 12 weeks. Biodegradation is established by determination of the dissolved organic carbon content of the supernatant liquor. This value is compared with that found for the liquor obtained from a control tube dosed with settled sewage only.
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  • 34
    ISBN: 9789264070745
    Language: English
    Pages: Online-Ressource (8 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 4
    Parallel Title: Parallelausg. Essai n 410; Toxicité cutanée à doses répétées; 21/28 jours
    Parallel Title: Parallelausg. Essai n 410: Toxicité cutanée à doses répétées: 21/28 jours
    Keywords: Environment
    Abstract: This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat, rabbit or guinea pig. At least 10 animals (5 female and 5 male) with healthy skin should be used at each dose level (at least three). The highest dose level should result in toxic effects but not produce an incidence of fatalities. The limit test corresponds to one dose level of at least 1000 mg/kg body weight. The method is based on the repeated application of the substance of interest during one limited period (several hours daily during 21/28 days). The test substance should be applied over not less than 10 per cent of the body surface area. The results of this study include: measurements and daily and detailed observations (haematology, clinical biochemistry and urinalysis), as well as gross necropsy and histopathology. A properly conducted 21-day or 28-day study should provide information on the effects of repeated inhalation exposure and can indicate the need for further longer term studies and provide information on the dose levels of the latter.
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  • 35
    ISBN: 9789264069503
    Language: English
    Pages: Online-Ressource (6 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 101; Spectres d'Absorption UV-VIS
    Parallel Title: Parallelausg. Essai n 101: Spectres d'Absorption UV-VIS
    Keywords: Environment
    Abstract: This Test Guideline describes the determining of the ultraviolet-visible (UV-VIS) absorption spectrum of a chemical compound to have some indication of the wavelengths at which the compounds may be susceptible to photochemical degradation. Degradation will depend upon the total energy absorbed in specific wavelength regions. The absence of measurable absorption does not preclude the possibility of photodegradation. This method utilises a double-beam spectrophotometer which records only the absorption differences between the blank (the solvent and all present chemical species other than the test chemical) and test solutions to give the spectrum of the chemical being tested. The test should be carried out at 25°C. The test solutions should be made up in a concentration which will result in at least one absorbance maximum in the range 0.5 to 1.5 units.
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  • 36
    ISBN: 9789264069688
    Language: English
    Pages: Online-Ressource (13 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 110; Distribution de la Taille des Particules/ Distributions de la Longueur et du Diamètre des Fibres
    Parallel Title: Parallelausg. Essai n 110: Distribution de la Taille des Particules/ Distributions de la Longueur et du Diamètre des Fibres
    Keywords: Environment
    Abstract: This Test Guideline describes two methods. These tests are applicable only to water insoluble (solubility 〈 10-6 g/1) substances. The first method described (Method A) is designed to provide information on the transportation and sedimentation of insoluble particles in water and air. There are several standard methods available which meet the sensitivity requirements: the sedimentation, the centrifugation or the coulter counter. The sample should be subjected to a simple light microscopic examination to determine the approximate nature of the particles. Data are obtained for a 3 size ranges ›200µm, ‹2 µm and the region 2to 200µm. Method A, which determines the effective hydrodynamic radius, Rs (only in the range 2 μm 〈 Rs 〈 100 μm), can be used for both fibrous and non-fibrous particulates. The Method B is used in the special case of materials which can form fibres, it is comparatively specialised, infrequently required and involves microscopic examination. Scanning (SEM) or transmission (TEM) electron microscopy are required. There is no standard procedure at present. The full length (l) and diameter (d) data are needed on fibre of dimensions d≥ 0.1µm and l≥ 5µm. Two histograms should be prepared based on examination of at least 50 fibres each.
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  • 37
    ISBN: 9789264069640
    Language: English
    Pages: Online-Ressource (7 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 108; Capacité à former des complexes dans l'eau
    Parallel Title: Parallelausg. Essai n 108: Capacité à former des complexes dans l'eau
    Keywords: Environment
    Abstract: This Test Guideline describes the polarographic method. The ability of a substance to form complexes with metals can be assessed by means of polarographic techniques which allow the determination of stability constants for some complexes. The polarographic method can be applied to substances with a water solubility greater than 10-5 M. This method is based on the fact that the reduction potentials of metal ions are shifted, usually to more negative values, as a result of complex formation. A minimum of four known concentrations of the chemical being tested should be investigated with a known concentration of metal ions. The chemical being tested should normally be present in at least a 25-fold excess over the metal ion concentrations. The current should be measured at applied potentials in the range - 0.2 V to -1.0 V. In order to detect complexes which form slowly, it is necessary to allow the solutions to stand under a nitrogen atmosphere for a minimum period of 24 hours. If the results are not significant, it is necessary to use methods based on different physicochemical principles, such as spectrophotometry or nuclear magnetic resonance spectrometry.
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  • 38
    ISBN: 9789264069749
    Language: English
    Pages: Online-Ressource (9 p.)
    Series Statement: OECD Guidelines for the Testing of Chemicals, Section 1
    Parallel Title: Parallelausg. Essai n 113; Essai de sélection pour la stabilité thermique et la stabilité dans l'air
    Parallel Title: Parallelausg. Essai n 113: Essai de sélection pour la stabilité thermique et la stabilité dans l'air
    Keywords: Environment
    Abstract: This Test Guideline describes methods for determining storage stability of a substance with respect to heat and air. Two methods are applicable to homogeneous solid and liquid substances and to mixtures of these: the accelerated storage test and the thermal analysis methods.In the accelerated storage test (CIPAC), a long duration storage instability can be simulated by applying a higher temperature during a short test. This test calls for the controlled storage at 54°C to 55°C for 14 days and subsequent analysis. In simple cases, it will be enough to determine a characteristic property before and after storage. The substance is considered to be stable at room temperature if the melting point has remained constant or the content of original substance as determined by analysis has decreased by not more than 5 per cent. In the thermal analysis methods (TGA and DTA), the sample and the standard reference material are heated up to the final temperature at a constant rate in a defined test atmosphere, either separately in a TGA or DTA apparatus, or in a combined system. The weight change of the sample or the quantities of heat absorbed or given off are measured and recorded. The substance is considered to be stable at room temperature if no decomposition or chemical transformation is found below 150°.
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