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  • Undetermined  (1,041)
  • Basel : MDPI - Multidisciplinary Digital Publishing Institute  (1,041)
  • Stuttgart : Kohlhammer
  • [Erscheinungsort nicht ermittelbar] : KIT Scientific Publishing
  • History of engineering & technology  (658)
  • Medicine  (384)
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  • 1
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561752 , 9783036561769
    Language: Undetermined
    Pages: 1 Online-Ressource (250 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The 2020 IEEE International Conference on High Voltage Engineering (ICHVE 2020) was held on 6–10 September 2020 in Beijing, China. The conference was organized by the Tsinghua University, China, and endorsed by the IEEE Dielectrics and Electrical Insulation Society. This conference has attracted a great deal of attention from researchers around the world in the field of high voltage engineering. The forum offered the opportunity to present the latest developments and different emerging challenges in high voltage engineering, including the topics of ultra-high voltage, smart grids, and insulating materials
    Note: English
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  • 2
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564098 , 9783036564081
    Language: Undetermined
    Pages: 1 Online-Ressource (200 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: In collaboration with the MDPI publishing house, we are pleased to introduce the reader to our new project, a Special Issue entitled “Advanced Eco-friendly Wood-Based Composites”. This Special Issue provides an opportunity to investigate advanced eco-friendly wood-based composites from a broader perspective. The coronavirus pandemic and shutdown measures employed to contain it, as well as the ongoing war in Ukraine, have influenced and decelerated the world economy and adversely impacted research activities on most levels in all countries. Surprisingly, researchers in the field of wood-based composites have continued to make progress, which is also described in this Special Issue
    Note: English
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  • 3
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562773 , 9783036562780
    Language: Undetermined
    Pages: 1 Online-Ressource (150 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: This reprint focuses on new trials related to cataract surgery, intraocular lens power calculations for cataracts after refractive surgery, problems related to high myopia, toric IOL power calculations, etc. Intraoperative use of the 3D Viewing System and OCT, studies on the spectacle dependence of EDOF, IOL fixation status and visual function, and dry eye after FLAC are also discussed. Proteomic analysis of aqueous humor proteins is also discussed
    Note: English
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  • 4
    ISBN: 9783036555751 , 9783036555768
    Language: Undetermined
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint aims to collect state-of-the-art research contributions that address challenges in the emerging 5G networks design, dimensioning and optimization. Designing, dimensioning and optimization of communication networks resources and services have been an inseparable part of telecom network development. The latter must convey a large volume of traffic, providing service to traffic streams with highly differentiated requirements in terms of bit-rate and service time, required quality of service and quality of experience parameters. Such a communication infrastructure presents many important challenges, such as the study of necessary multi-layer cooperation, new protocols, performance evaluation of different network parts, low layer network design, network management and security issues, and new technologies in general, which will be discussed in this book
    Note: English
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  • 5
    ISBN: 9783036558134 , 9783036558141
    Language: Undetermined
    Pages: 1 Online-Ressource (284 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint is concerned with the microstructural characterization and the defect analysis of metallic additively manufactured (AM) materials and parts. Special attention is paid to the determination of residual stress in such parts and to online monitoring techniques devised to predict the appearance of defects. Finally, several non-destructive testing techniques are employed to assess the quality of AM materials and parts
    Note: English
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  • 6
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565675 , 9783036565668
    Language: Undetermined
    Pages: 1 Online-Ressource (294 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The purpose of this Special Issue was to attract papers in the new era of sustainability and food packaging that address all major sectors of the food industry from cereals and confectionery to fruits and vegetables, meat, and dairy products
    Note: English
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  • 7
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563893 , 9783036563886
    Language: Undetermined
    Pages: 1 Online-Ressource (190 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: This reprint is the compilation of the articles submitted in the Special Issue entitled “Metallic or Metallic Oxide (Photo)catalysts for Environmental Applications” from the journal Catalysts, which gives an overview of the latest advances in the development of metallic or metallic oxide (photo)catalytic materials, with environmental applications for the elimination of organic pollutants or the valorization of biomass
    Note: English
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  • 8
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563824 , 9783036563831
    Language: Undetermined
    Pages: 1 Online-Ressource (386 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint focuses on the application of the combination of synthetic aperture radars and depth learning technology. It aims to further promote the development of SAR image intelligent interpretation technology. A synthetic aperture radar (SAR) is an important active microwave imaging sensor, whose all-day and all-weather working capacity give it an important place in the remote sensing community. Since the United States launched the first SAR satellite, SAR has received much attention in the remote sensing community, e.g., in geological exploration, topographic mapping, disaster forecast, and traffic monitoring. It is valuable and meaningful, therefore, to study SAR-based remote sensing applications. In recent years, deep learning represented by convolution neural networks has promoted significant progress in the computer vision community, e.g., in face recognition, the driverless field and Internet of things (IoT). Deep learning can enable computational models with multiple processing layers to learn data representations with multiple-level abstractions. This can greatly improve the performance of various applications. This reprint provides a platform for researchers to handle the above significant challenges and present their innovative and cutting-edge research results when applying deep learning to SAR in various manuscript types, e.g., articles, letters, reviews and technical reports
    Note: English
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  • 9
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564890 , 9783036564906
    Language: Undetermined
    Pages: 1 Online-Ressource (92 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The reprint is devoted to the phenomena associated with exact or approximate axial symmetry in different areas of technical physics and mechanical engineering science. How can the symmetry of the problem be used most efficiently for its analysis? Why is the symmetry broken or why is it still approximately retained? These and other questions are discussed based on systems from different fields of engineering
    Note: English
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  • 10
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563411 , 9783036563404
    Language: Undetermined
    Pages: 1 Online-Ressource (250 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: The Special Issue consists of 13 submitted papers. We acknowledge all authors for their contributions. We recognize that interest in the topics is expanding and are confident that the findings are beneficial to our readers
    Note: English
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  • 11
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562353 , 9783036562360
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Service life prediction is crucial for the adoption of more sustainable solutions, allowing developers to optimize the costs and environmental impact of buildings during their life cycle. An accurate assessment of the service life of buildings requires a thorough understanding of the degradation mechanisms and behaviour of the construction materials. Building pathology assessment methods characterize the deterioration state of buildings, using specific measurable properties as indicators. Based on this information, different service life prediction methodologies can be defined to provide reliable data concerning the most probable failure time of whole buildings and individual components according to their characteristics and their age. This Special Issue provides new perspectives on the existing knowledge related with various aspects of the Assessment, Diagnosis and Service Life Prediction of buildings and their components. The ten original research studies published in this Special Issue result from research centres and university departments of Civil and Construction Engineering, Safety Management, Environmental Engineering, Geotechnical Engineering, and Architecture and the Built Environment, with relevant contributions from experts from Australia, Brazil, the Czech Republic, Hong Kong, Iran, Israel, Norway, Portugal, and Taiwan. The studies included in this Special Issue address topics related to: Building pathology assessment methods; Diagnosis of defects in buildings and components; Appropriate intervention and repair techniques; Deterministic and stochastic service life prediction models
    Note: English
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  • 12
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563527 , 9783036563534
    Language: Undetermined
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Biomimetic polymers and materials have been widely used in a variety of biomedical and pharmacological applications. Particularly, collagen-based biomaterials have been extensively applied in various biomedical fields, such as scaffolds in tissue engineering. However, there are many challenges associated with the use of mammalian collagen, including the issues of religious constrains, allergic or autoimmune reactions, and the spread of animal diseases. Over the past few decades, marine collagen (MC) has emerged as a promising biomaterial for biomedical and pharmacological applications. Marine organisms are a rich source of structurally novel and biologically active compounds, and to date, many biological components have been isolated from various marine resources. MC offers advantages over mammalian collagen due to its water solubility, low immunogenicity, safety, biocompatibility, antimicrobial activity, functionality, and low production costs. Due to its characteristics and physicobiochemical properties, it has tremendous potential for use as a scaffold biomaterial in tissue engineering and regenerative medicine, in drug delivery systems, and as a therapeutic. In this Special Issue, we encourage submissions related to the recent developments, advancements, trends, challenges, and future perspectives in this new research field. We expect to receive contributions from different areas of multidisciplinary research, including—but not restricted to—extraction, purification, characterization, fabrication, and experimentation of MC, with a particular focus on their biotechnological, biomedical and pharmacological uses
    Note: English
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  • 13
    ISBN: 9783036563282 , 9783036563299
    Language: Undetermined
    Pages: 1 Online-Ressource (348 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint focuses on a number of timely and challenging issues in areas that support the design, implementation, and experimental testing of single and multiple autonomous air, land, and marine robots. Special emphasis is placed on the methods and techniques employed for motion planning and control that are rooted in solid theoretical concepts. Applications are also addressed in the area of advanced manipulator control. The reprint affords the reader a well-balanced presentation of a wide spectrum of topics that include, but are not limited to, the generation of optimal collision-free trajectories for heterogeneous vehicles working collaboratively or independently, the rapid adaptation of manipulator trajectories to task perturbations, the automatic collision avoidance for surface vessels, the path following controllers for marine and ground robots, the large-scale swarm counterattack strategies, and the optimal actuator configuration design for over-actuated underwater robots
    Note: English
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  • 14
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564289 , 9783036564296
    Language: Undetermined
    Pages: 1 Online-Ressource (358 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: Ciguatoxins (CTXs), which are responsible for Ciguatera fish poisoning (CFP), are liposoluble toxins produced by microalgae of the genera Gambierdiscus and Fukuyoa. This book presents 18 scientific papers that offer new information and scientific evidence on: (i) CTX occurrence in aquatic environments, with an emphasis on edible aquatic organisms; (ii) analysis methods for the determination of CTXs; (iii) advances in research on CTX-producing organisms; (iv) environmental factors involved in the presence of CTXs; and (v) the assessment of public health risks related to the presence of CTXs, as well as risk management and mitigation strategies
    Note: English
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  • 15
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563626 , 9783036563633
    Language: Undetermined
    Pages: 1 Online-Ressource (172 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint focuses on forged steels as an interesting material family, both from a scientific and commercial point of view, due to their many applications. Despite their diffusion as a consolidated material, many research fields are actively employing new applications. At the same time, innovations are arising from the manufacturing process of such materials, including the possibility to manufacture them from metal powders suitable for 3D printing. This reprint embraces the interdisciplinary work covering physical metallurgy and processing, reporting the experimental and theoretical progress concerning microstructural evolution during processing, and microstructure–properties relations
    Note: English
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  • 16
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564678 , 9783036564661
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Medicine
    Abstract: Hyperbaric oxygen is a known therapeutic agent, and treatments using this agent remain a matter of discussion and research. This Special Issue collection will add new knowledge and also offer some not so usual approaches to foster contemporary understanding and potential benefit for patients and scholars
    Note: English
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  • 17
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036560878 , 9783036560885
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Medicine
    Abstract: The Special Issue provides twelve contributions, of which three original articles, seven narrative reviews, one systematic review, and one meta-analysis that, altogether, offer a multifaceted and multidisciplinary overview that allows to draw a picture as intriguing and fascinating as possible on the benefits of curcumin and also to suggest potential fields of activities still to be explored. Among the biological activities exerted by curcumin, the anti-oxidative and anti-inflammatory properties reported in many studies make it a potential effective tool in preventing and counteracting chronic-degenerative diseases, very often associated with obesity and aging, such as cardiovascular diseases, T2D, metabolic dysfunctions, neurodegenerative diseases, and cancer, all of them characterized by the presence of oxidative and inflammatory processes. The main concerns that arise from the evaluation of the preventive/therapeutic effects of curcumin are, first of all, the still small number of randomized placebo-control studies available; in addition, small sample sizes have generally been considered, and different protocols and different formulations as well as different routes of administration of curcumin have been used. Thus, it is quite difficult to compare the results and to provide a standard protocol for the use of this promising natural compound. For these reasons, and taking in account the growing use of curcumin by the general population, further investigations to confirm and expand current findings are mandatory and research on curcumin and its effects on human health have to be fostered and promoted
    Note: English
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  • 18
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563954 , 9783036563947
    Language: Undetermined
    Pages: 1 Online-Ressource (440 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Industry & industrial studies
    Abstract: This reprint includes 22 research papers and an editorial, collected from the Special Issue "Modelling, Monitoring, Control and Optimization for Complex Industrial Processes", highlighting recent research advances and emerging research directions in complex industrial processes. This reprint aims to promote the research field and benefit the readers from both academic communities and industrial sectors
    Note: English
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  • 19
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036550558 , 9783036550565
    Language: Undetermined
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The Special Issue “Demand Response in Smart Grids” includes 11 papers on a variety of topics. The success of this Special Issue demonstrates the relevance of demand response programs and events in the operation of power and energy systems at both the distribution level and at the wide power system level. This reprint addresses the design, implementation, and operation of demand response programs, with focus on methods and techniques to achieve an optimized operation as well as on the electricity consumer
    Note: English
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  • 20
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565477 , 9783036565460
    Language: Undetermined
    Pages: 1 Online-Ressource (294 p.)
    Keywords: Medicine ; Oncology
    Abstract: Colorectal cancer (CRC) is currently the third leading cause of cancer-related mortality, with 1.9 million incidence cases and 0.9 million deaths worldwide. The global number of new CRC cases is predicted to reach 3.2 million in 2040, based on the projection of aging, population growth, and human development.In clinics, despite advances of diagnosis and surgical procedures, 20% of the patients with CRC present with metastasis at the time of diagnosis, caused by residual tumor cells that have spread to distant organs prior to surgery, affecting the patient survival rate. Standard systemic chemotherapy, alternative therapies that target mechanisms involved in cancer progression and metastasis, immunotherapy, and combination therapies are the major CRC-treatment strategies. In the advanced stage of CRC the transforming growth factor-beta (TGF-β) plays an oncogenic role by promoting cancer cell proliferation, cancer cell self-renewal, epithelial-to-mesenchymal transition, invasion, tumor progression, metastatic spread, and immune escape. Furthermore, high levels of TGF-β1 confers poor prognosis and is associated with early recurrence after surgery, resistance to chemo- or immunotherapy, and shorter survival. Based on the body of experimental evidence indicating that TGF-β signaling has the potential to be a good therapeutic target in CRC, several anti-TGF-β drugs have been investigated in cancer clinical trials. Here, we presented a comprehensive collection of manuscripts regarding studies on targeting the TGF-β signaling in CRC to improve patient’s prognosis and personalized treatments
    Note: English
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  • 21
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562919 , 9783036562926
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This book focuses on recent advances in both theoretical and experimental studies of material behaviour at the micro- and nano-scales. Special attention is given to experimental studies of nanofilms, nanoparticles and nanocomposites as well as tooth defects. Various experimental techniques were used. Magneto- and thermoelastic coupling were considered, as were nonlocal models of thin structures
    Note: English
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  • 22
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563879 , 9783036563862
    Language: Undetermined
    Pages: 1 Online-Ressource (254 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint collects 10 original research contributions published in the Special Issue entitled “Artificial Intelligence for Multisource Geospatial Information” of the ISPRS International Journal of Geo-Information. The focus is on different methods of Geospatial Artificial Intelligence (GeoAI) based on deep learning using different network architectures, clustering, soft computing, and semantic approaches. They are proposed to deal with a variety of Geospatial Big Data (GBD), such as georeferenced texts and photos in social networks, remote sensing images, cartographic maps, multidimensional geo databases, metadata in spatial data infrastructures, and for different tasks, such as for multisource georeferenced text integration and geodata flexible querying, for social sensing by applying sentiment analysis, clustering and geo analysis, for segmentation of roads, clouds and snow, and for detection of small targets and people on the streets
    Note: English
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  • 23
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562964 , 9783036562957
    Language: Undetermined
    Pages: 1 Online-Ressource (296 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: This reprint is a compilation of the articles submitted in the Special Issue entitled, “Heterogeneous Photocatalysis: A Solution for a Greener Earth”, from the journal Catalysts, which presents an overview of the latest advances in the development of innovative photocatalytic processes
    Note: English
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  • 24
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563855 , 9783036563848
    Language: Undetermined
    Pages: 1 Online-Ressource (220 p.)
    Keywords: Medicine
    Abstract: This reprint is a compilation of ten publications, including original-research and review articles, and the accompanying editorial within the scope of a Special Issue entitled: "State of the Art in Idiopathic Pulmonary Fibrosis" published in Cells
    Note: English
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  • 25
    ISBN: 9783036565200 , 9783036565194
    Language: Undetermined
    Pages: 1 Online-Ressource (214 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This Special Issue, "Temperature Reduction Technologies Meet Asphalt Pavement: Green and Sustainability", covers various subjects related to advanced temperature reduction technologies in bituminous materials. It can help civil engineers and material scientists better identify underlying views for sustainable pavement constructions
    Note: English
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  • 26
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561943 , 9783036561936
    Language: Undetermined
    Pages: 1 Online-Ressource (264 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: The rapid expansion of aquaculture around the world is increasingly being impacted by toxins produced by harmful marine microalgae, which threaten the safety of seafood. In addition, ocean climate change is leading to changing patterns in the distribution of toxic dinoflagellates and diatoms which produce these toxins. New approaches are being developed to monitor for harmful species and the toxins they produce. This Special Issue covers pioneering research on harmful marine microalgae and their toxins, including the identification of species and toxins; the development of new chemical and biological techniques to identify and monitor species and toxins; the uptake of marine biotoxins in seafood and marine ecosystems; and the distribution and abundance of toxins, particularly in relation to climate change
    Note: English
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  • 27
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561103 , 9783036561097
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Medicine
    Abstract: The clinical spectrum of systemic lupus erythematosus (SLE) is highly heterogeneous, ranging from mild disease, which can be limited to skin and joint involvement, to life-threatening conditions with renal impairment, severe cytopenias, central nervous system disease, and thromboembolic events. Apart from the host genetics, several environmental factors, such as sunlight, infections, drugs, and probably hormonal factors, can trigger the onset of symptoms related to SLE. Despite significant advances in our understanding of the pathophysiology and optimization of medical care, patients with SLE still have significant rates of premature mortality and many patients experience severe disease with increased risk of sustaining organ damage and having a reduced health-related quality of life. The development of effective drugs that can induce remission or low disease activity, the unanimous use of definitions of remission and low or high disease activity, flare, and response to therapy, the identification of non-invasive biomarkers of disease activity and long-term outcomes, and the implementation of SLE patients’ perspectives as an integral part of the clinical assessment constitute only a few of the many unmet needs in the field of SLE
    Note: English
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  • 28
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036559995 , 9783036560007
    Language: Undetermined
    Pages: 1 Online-Ressource (260 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: Plant stress could be defined as any unfavorable condition or substance that can affect or block the metabolism, growth or development of a plant. The response of the plant may vary depending on the frequency and intensity of the stressor, as well as the developmental stage of the plant. Plants, throughout their life cycle, are exposed to a large number of conditions or stressors. Abiotic stress is stress caused by non-living agents. Depending on the nature of the causal agent, it can be divided into physical and chemical. Physical (actually, physical-chemical) stresses include water deficits, salinity (in its osmotic component), temperature extremes (heat, cold, freezing), excessive or insufficient irradiation, anaerobiosis caused by waterlogging or flooding, mechanical stress caused by wind or excessive soil compaction and stress induced by wounds or injuries. Chemical stress is caused by salinity (in its ionic or toxic component), by the lack of mineral elements and by environmental pollutants such as sulphur dioxide (SO2), nitrogen oxides (NOx), chlorofluorocarbon compounds (CFCs), ozone (O3) and metals. The abiotic stresses that most negatively affect growth and production are probably drought, salt stress and temperature stress (high and low temperatures), all of which are associated with climate change
    Note: English
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  • 29
    ISBN: 9783036563503 , 9783036563510
    Language: Undetermined
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: The objective of this collection is to illustrate the most recent research on the development of novel and/or rapid methods for mycotoxin determination, and to propose new strategies for monitoring and/or reducing mycotoxin contamination. Innovative sample preparation techniques or protocols and the possibility of multiclass mycotoxin detection will be very positively considered for possible inclusion in this Special Issue. Both methods based on (bio)sensors and chromatography with various detectors (including mass spectrometry) are welcome. Applications of already published methods on new matrices without any modification will not be accepted. However, extensive studies and monitoring on the spread of contamination through the food production chain could be of interest for this collection
    Note: English
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  • 30
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562698 , 9783036562704
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: Researchers have made great progress in the mechanism of mycotoxins biosynthesis, pathogenicity, and the construction of detection methods. This collection holds fundamental and applied research on pathogenic fungi and mycotoxins in China, which directly or indirectly affect the health of plants, animals, and humans. Some papers mainly study the mechanism of mycotoxin biosynthesis, including the crucial genes, environmental factors, and regulation mechanisms, which is beneficial to advancing our knowledge of this area. Some papers focus on the toxicity of mycotoxins, which is helpful to the detoxification of mycotoxins and the reduction of the hazardous effect of mycotoxins. Special attention is given to the leading detection methods, especially on-site rapid detection. These effective and feasible methods are important for discovering and controlling the risk of mycotoxins
    Note: English
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  • 31
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036559698 , 9783036559704
    Language: Undetermined
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: This Special Issue on CFS/ME collects 18 papers with an interdisciplinary view on the current demographic and epidemiological data and immunological characteristics of CFS/ME and examines the different pathogenic hypotheses, as well as giving information about the latest knowledge on diagnostic investigations, pharmacological, integrative, physical, cognitive-behavioral and psychological curative approaches
    Note: English
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  • 32
    ISBN: 9783036557618 , 9783036557625
    Language: Undetermined
    Pages: 1 Online-Ressource (432 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: With the increasing requirements for energy, resources, and space, numerous rock engineering projects (e.g., mining, tunnelling, underground storage, and geothermal and petroleum engineering) are more often being constructed and operated in large-scale, deep underground, and complex geology environments. Meanwhile, more and more unconventional rock failures and rock instabilities (e.g., rockbursts, large-scale collapses, and mine earthquakes) are occurring and severely threatening the safety of underground operations. It is well-recognized that rocks have multiscale structures from minerals, particles, fractures, fissures, joints, and stratification to faults and involve multiscale fracture processes. In the deep earth, rocks are commonly subjected to complex high-stress and strong-dynamic disturbances simultaneously. In addition, there are many multiphysics coupling processes, such as the coupled thermo-hydromechanical interaction in fractured porous rocks. It is still difficult to understand rock mechanics and to characterize rock behaviors with complex stress conditions, multiphysics processes, and multiscale changes. The primary aim of this Special Issue is to bring together original research discussing innovative efforts on analytical, numerical, and big-data-based methods in rock mechanics. It includes 25 manuscripts that illustrate the richness and challenging nature of deep rock mechanics
    Note: English
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563541 , 9783036563558
    Language: Undetermined
    Pages: 1 Online-Ressource (144 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The need for electromechanical energy conversion that takes place in electric motors, generators, and actuators is an important aspect associated with current development. The efficiency and effectiveness of the conversion process depends on both the design of the devices and the materials used in those devices. In this context, this book addresses important aspects of electrical machines, namely their materials, design, and optimization. It is essential for the design process of electrical machines to be carried out through extensive numerical field computations. Thus, the reprint also focuses on the accuracy of these computations, as well as the quality of the material models that are adopted. Another aspect of interest is the modeling of properties such as hysteresis, alternating and rotating losses and demagnetization. In addition, the characterization of materials and their dependence on mechanical quantities such as stresses and temperature are also considered. The reprint also addresses another aspect that needs to be considered for the development of the optimal global system in some applications, which is the case of drives that are associated with electrical machines
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  • 34
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563787 , 9783036563794
    Language: Undetermined
    Pages: 1 Online-Ressource (112 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: In this Special Issue, you will find new directions in the research on liquid crystal applications. To be honest, we were surprised to find 10 papers covering a variety of application areas, with no overlap between them. The only important application without a related article was “display”! This was exactly the situation we hoped for. In this Special Issue, you can find 10 articles discussing the applications of LC devices or LC materials. The applications are liquid crystal on silicon (LCOS) for optical communication, laser processing and wireless optical charging, wavelength selective filters, waveguides, smart windows, LCDs for terahertz waves, LC polymers for polarizing grating and LC material for an ink.We believe that this Special Issue will help researchers focusng on optical devices or LC materials to obtain inspiration for new devices using liquid crystals
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    ISBN: 9783036570815 , 9783036570808
    Language: Undetermined
    Pages: 1 Online-Ressource (294 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint covers topics on geographical scale of glacier and lake ice variations, as well as the engineering scale of ice properties and their practical applications via laboratory tests and numerical modeling
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  • 36
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568614 , 9783036568607
    Language: Undetermined
    Pages: 1 Online-Ressource (388 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: With increasing attention on the reduction of CO2 emissions, the sustainability of construction materials has become one of the most growing issues in concrete science and engineering research fields. New sustainable construction materials, such as alkali-activated materials, calcium sulfoaluminate (CSA) cement, and limestone calcined clay cement (LC3), have been suggested and high-performance and/or highly durable construction materials using special admixtures, such as nanomaterials, have been studied to reduce the environmental impact during the life cycle of construction materials.This Special Issue aims to highlight and share recent findings in developing new sustainable cementitious materials, modeling their hydration kinetics, investigating their microstructure, improving the performance and durability of cementitious materials using functional supplementary ingredients, suggesting novel test methods for new construction materials, etc. In this Special Issue are presented the following areas:Sustainable concrete and alternative binders;Hydration kinetics of sustainable cementitious materials;Characterization of sustainable cementitious materials;Re-utilization of industrial by-products for construction materials;High strength and durable cementitious materials;Property enhancement by functional additives;Energy storage through construction materials
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  • 37
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568522 , 9783036568539
    Language: Undetermined
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Medicine ; Epidemiology & medical statistics
    Abstract: This reprint focuses on field studies aimed at unraveling the complex networks created by interactions between parasites and hosts in a given ecosystem. Since most transboundary diseases have been propagated from the wilderness to anthropized areas, societies are increasingly concerned about the relevance of wildlife as it pertains to global health. In this respect, research on parasites that may affect the biology and population equilibrium of wildlife is of major interest, especially when a One Health perspective is considered. The studies compiled in the present Special Issue fall within several areas of interest, such as epidemiology, diagnosis, emerging zoonoses, food safety, conservation issues, parasite–host interactions, and the pathology of infections caused by parasites in wild host species
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  • 38
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568881 , 9783036568898
    Language: Undetermined
    Pages: 1 Online-Ressource (148 p.)
    Keywords: Medicine ; Pharmacology ; Research & information: general ; Chemistry
    Abstract: The Special Issue reprint covers a wide range of applications of 3D-printing in dentistry. Five out of eleven research papers deal with applications of 3D printing in orthodontics, one study presents a 3D-printed fitting system for the FFP2 that were applied during the COVID-19 pandemic, and the others address applications in prosthodontics and restorative dentistry
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  • 39
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570365 , 9783036570372
    Language: Undetermined
    Pages: 1 Online-Ressource (238 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The automotive industry has always been synonymous with research and innovation, but nowadays the industry is adding pressure and is establishing the agenda of the researchers from the field. Visions have been provided, and the hardware and the software exist; the only question remaining is: “who is going to deliver”? To answer this question, we encouraged scientists, researchers, industry specialists, and academics to share their vision of autonomous vehicles. What will the platform look like? What kind of hardware and software is most suitable? Who will make the connection between these two interdependent environments (and how), so that in the end the AI will define the process? These are the pressing issues of the current moment, and this Special Issue will help all those interested in the topic to promote their vision and ideas. Since the automotive field does not belong to a classical scientific field but has become an independent self-made scientific branch, all those who felt that they could contribute to this highly dynamic environment were requested to join in promoting their particular research or reviews in this Special Issue coordinated from both academia and the industry
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  • 40
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567624 , 9783036567631
    Language: Undetermined
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Mining technology & engineering
    Abstract: Heusler type magnetic shape memory alloys (MSMAs) have gained a strong academic and practical importance during recent decades due to the giant effects they exhibit, particularly magnetostrain produced by magnetic field-induced twin boundaries motion and magneto(elasto)-caloric effects resulting from the magnetic field-induced martensitic transformation. This Special Issue intends to communicate the latest advances in R&D and theory of MSMAs. This book consists of a collection of eleven invited peer-reviewed papers, each detailing a particular aspect in the fundamental and/or applied investigation of MSMAs and related phenomena. The papers are a corpus of up-to-date information on the ongoing studies of MSMAs. It is hoped that this reprint will be useful to physicists and materials scientists, both specialists and graduate students, and enable future technological breakthroughs in engineering
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  • 41
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570419 , 9783036570402
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy
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  • 42
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567587 , 9783036567594
    Language: Undetermined
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: Supply Chain 4.0 is designed, planned, managed and optimized using Industry 4.0 technologies. There are many research issues and challenges associated with Supply Chain 4.0, a data rich complex system. The available data can interpret what happened in the past, what is currently happening, what will happen in the future and what are the best actionable decisions. Digitalization, visibility, connectivity and interoperability are integrated in Supply Chain 4.0. The operational, tactical and strategic plans across the supply chain are digitally interlinked and real-time synchronized with a 360-degree view. The win–win partnerships are dynamic and sustainable, with agility, flexibility and responsiveness to uncertain business environments. New models and methods are advocated to implement Supply Chain 4.0 research and development. With the progress and implementation of Industry 4.0 technologies, it is anticipated that there will be more and more breakthroughs in the models and methods of Supply Chain 4.0. This Special Issue will serve as a helpful reference for Supply Chain 4.0 researchers and practitioners
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  • 43
    ISBN: 9783036572017 , 9783036572000
    Language: Undetermined
    Pages: 1 Online-Ressource (296 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: The Special Issue "Focus on Antibiotics - New Challenges and Steps Forward in Discovery and Development" addresses the latest efforts towards discovering new antibiotics. The articles in this Special Issue cover various topics concerning antibacterial drugs. They provide valuable insights into the challenges and opportunities facing the field of antibiotic research and offer innovative solutions to tackle the growing problem of antibiotic resistance. The content of this Special Issue addresses antibacterial quinolones of the latest generation, new tetracyclines (such as glycylcyclines, aminomethylcyclines, and fluorocyclines), metal complexes (Ru (II/III) frameworks and Co(III) complexes with diamine chelate ligands), various nanoparticles (gold, silver and titanium dioxide nanoparticles), bioactive compounds produced by Mixobacterials species, anti-mycobacterial compounds acting as phosphopantetheinyl transferase inhibitors. The research in this Special Issue will contribute to pharmaceutics and ultimately contribute to developing new and effective antibiotics. We are grateful to the authors for their contributions and hope this Special Issue will stimulate further research and discussion on antibiotics. We also thank the reviewers for their time and expertise, and the editorial team for supporting this Special Issue. Finally, we hope this Special Issue will serve as a valuable resource for researchers, clinicians, and policymakers working towards a future where antibiotics remain vital in our fight against infectious diseases
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  • 44
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568461 , 9783036568478
    Language: Undetermined
    Pages: 1 Online-Ressource (290 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: The thermal analysis of materials encompasses a variety of methods used to detect changes in material properties as a function of temperature. Before temperature measurement became routine in all stages of metal and ceramic processing, early metallurgists relied on the color and brightness of hot metal, and glassmakers used viscosity for guidance. Nowadays, techniques of differential thermal analysis (DTA) and differential scanning calorimetry (DSC) routinely yield heat capacities, temperatures, and enthalpies of phase transformations in the temperature range from −150 to 1500 °C. The measurement of any physical property as a function of temperature brings the method into the realm of thermal analysis. This Special Issue provides a sampling of the current use, diversity, and ongoing developments of techniques and approaches in the thermal analysis of materials. It combines contributions solicited by editors that reflect their scientific interests and networks, with generally related submissions received over two years. It contains 16 articles and 1 short review submitted by authors from 10 countries
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  • 45
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570624 , 9783036570631
    Language: Undetermined
    Pages: 1 Online-Ressource (222 p.)
    Keywords: Medicine
    Abstract: Diet contributes to the development of many chronic conditions including obesity, cardiovascular disease, hypertension, stroke, type 2 diabetes, metabolic syndrome, some cancers, non-alcoholic fatty liver disease, and potentially some neurological diseases. This reprint addresses associations between diet (and specific nutrients including vitamin D) and various chronic diseases including obesity, cardiovascular disease, hypertension, stroke, diabetes, metabolic syndrome, non-alcoholic fatty liver disease, neurological conditions, and age-related macular degeneration. More specifically, the impacts of plant-based diets, dairy products, and ketogenic diets are explored in relation to chronic disease risk as well as some benefits of the consumption of oral nutritional supplements in the prevention of malnutrition and sarcopenia and in the treatment of wounds in individuals with diabetes. Additional topics that are covered include some roles of the fatty acid arachidonic acid in the body and the impact of cellular mitochondrial dysfunction on the progression of age-related macular degeneration. The effectiveness of a variety of nutraceuticals is covered as a means for the prevention or treatment of age-related macular degeneration. Lastly, the use of olive oil in reducing gut permeability in those with pre-diabetes is addressed, as well as the complex relationships of diet/food and of disease (metabolic syndrome) with the gut microbiota
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  • 46
    ISBN: 9783036569871 , 9783036569864
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The second volume of the Special Issue on “Micro-Electro Discharge Machining: Principles, Recent Advancements and Applications” confirms the growing interest in the micro-EDM technology as a suitable and efficient technology for machining novel, multilateral components, with demanding requirements in terms of precision, accuracy, and productivity.This volume consists of 10 original research papers which involve several approaches to micro-EDM and cover the enhancement of the process performance, such as the material removal rate, surface roughness, or machining accuracy, using advanced optimization methods. Some studies also consider several dielectric fluid additives and investigate the processability of new materials. Others investigate the combination of Reverse-micro-EDM with laser beam micromachining or explore new applications for the micro-EDM for fabricating antimicrobial nanosilver colloid
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  • 47
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569369 , 9783036569376
    Language: Undetermined
    Pages: 1 Online-Ressource (78 p.)
    Keywords: Medicine
    Abstract: The objective of this reprint is to present the main evidence-based data on new developments and knowledge in diagnostic and treatment technologies in the orofacial field used in both children and adults. The published content has been met with great success in interdisciplinary fields, stimulating international authors to submit their original articles, reviews, or case reports based on various aspects of orthodontics as well as on the diagnosis and management of temporomandibular disorders and orofacial pain. Among the current highly debated topics, this reprint focuses on multiple disciplines as follows: gingival recessions and periodontal status after orthodontic treatment; a rare case of impacted central incisors; predictors of analgesic consumption in orthodontic patients; a systematic review about different dentoskeletal class III treatment approaches; evaluation of upper airway volumes; and cephalometric values in JIA patients
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  • 48
    ISBN: 9783036566740 , 9783036566757
    Language: Undetermined
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: This reprint covers works related to research on the environments of coastal zones and inland waters, solving complex and current scientific problems in these areas. Tasks undertaken by the authors address current research trends using contemporary remote sensing techniques and cover various thematic areas or scientific approaches. Some works propose new possibilities of using geospatial data or methods of remote sensing data processing. They include issues related to the use of augmented and virtual reality, object-oriented image analysis, UAV-based photogrammetry, fusion of hydroacoustic and photogrammetric data, spatial interpolation, and geodata reduction techniques. These methods are being developed to support safe navigation in inland waters; low-cost monitoring of underwater objects; creating bathymetric maps and topobathymetric digital models or mapping submerged aquatic vegetation. The papers also focus on improving existing solutions and demonstrate new research approaches, including atmospheric correction, adjacency effects for remotely sensed images, classification of wetland vegetation, as well as determining the speed of sound in shallow waters for hydrography applications. These papers demonstrate the potential of the information contained in the remote sensing data acquired by the various platforms, as well as techniques for image processing based on the Google Earth Engine (GEE)
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  • 49
    ISBN: 9783036566009 , 9783036566016
    Language: Undetermined
    Pages: 1 Online-Ressource (190 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Our era is characterized by two major phenomena. On the one hand, we are confronted by climate and environmental crises constituted by, among others, changing weather patterns, loss of biodiversity and natural wildlife, and ecosystem degradation. On the other hand, we are experiencing an ongoing technological evolution culminating in the rise of artificial intelligence (AI). The popular notion of “AI for Sustainability” constitutes an attempt to connect these two phenomena in a beneficial way by using AI to alleviate climate and environmental worries. AI is increasingly being used in the analysis, mitigation, and prevention of the climate and environmental crises and their effects. Much less attention has been paid to the idea of the “Sustainability of AI”, which focusses on the materiality of AI technologies themselves. Indeed, what are the hidden costs of AI? Although we use AI in combatting the climate and environmental crises, does it not have its own contributions to these crises? And, if so, how do we account for these contributions? The Special Issue is the first attempt to address the topic of “Sustainable AI” from a multi-disciplinary perspective. The authors that contributed to this issue come from diverse fields such as philosophy, ethics, sociology, law, and engineering. The included papers represent the first steps in understanding what it means to tackle the climate and environmental crises with AI while refraining from aggravating these crises
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  • 50
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568089 , 9783036568096
    Language: Undetermined
    Pages: 1 Online-Ressource (150 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The motivation for the present reprint is to provide an overview of novel applications of AI methods to industrial control systems by means of selected best practices in highlighting how such methodologies can be used to improve the production systems self-learning capacities, their overall performance, the related process and product quality, the optimal use of resources and the industrial systems safety, and resilience to varying boundary conditions and production requests. By means of its seven scientific contributions, the present reprint illustrates the increasing added value of the introduction of AI methods for improving the performance of control solutions with reference to different control and automation problems in different industrial applications and sectors, ranging from single manipulators or small unmanned ground vehicles up to complex manufacturing. Additionally, the role of AI to improve the performance of relevant engineering methodologies and digital instruments, such as cyberphysical systems, digital twins, and human–robot collaboration, are also effectively addressed in the included contributions
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570037 , 9783036570020
    Language: Undetermined
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Medicine
    Abstract: Steroids are essential hormones that regulate biological processes across their lifespan. Steroid hormone production and action must be tightly controlled otherwise there can be detrimental effects on physiological function leading to disease. This reprint contains original and review articles by experts at the cutting edge of their fields published in a Special Issue on the “Molecular mechanisms of steroid hormone biosynthesis and action” of the International Journal of Molecular Sciences. The topics include: 1) Steroid hormone biosynthesis, including substrate availability, mechanism of steroidogenic enzyme action, and the impact of mutations; 2) Molecular and cellular regulation of steroidogenesis, including steroidogenic cell response to hormone stimulation, signaling pathways, kinases, transcription factors, and gene expression; 3) Molecular mechanisms of endocrine disruptor action on steroidogenic cells; and 4) New tools and approaches to detect and study steroid hormones
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  • 52
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569161 , 9783036569178
    Language: Undetermined
    Pages: 1 Online-Ressource (274 p.)
    Keywords: Medicine ; Oncology
    Abstract: Tumor progression is linked to a switch in the balance between positive and negative regulators, and mainly depends on the release by inflammatory or neoplastic cells of specific growth factors. Inflammatory infiltration contributes to tumor progression and metastatic process, and there are many reports of associations between tumor inflammatory infiltration, progression and prognosis. New therapeutic approaches have been developed with the aim to control tumor progression through the targeting of different components of the tumor microenvironment. This reprint will be useful for anyone who wants to learn about cancer: professors and students at universities, scientists at research institutes, biotechnology, and pharmaceutical labs, and lawyers trying to understand the patent literature
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569987 , 9783036569994
    Language: Undetermined
    Pages: 1 Online-Ressource (186 p.)
    Keywords: Medicine ; Neurosciences
    Abstract: The development of in vivo neuroimaging techniques has yielded an incredible amount of digital information about the brain. Neuroimaging techniques are increasingly being used to study human cognitive processes, create brain–machine interfaces, and also to identify and diagnose certain brain disorders. Currently, neuroscientists and medics actively use different methods for brain scans, including electro- and magnetoencephalography (EEG/MEG), functional near-infrared spectroscopy (fNIRS), electrocorticography (ECoG), functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and diffusion tensor imaging (DTI). Recent advances in signal processing and machine learning for neuroimaging data using various signal processing methods have made impressive progress in solving a number of practical tasks in medicine, healthcare, neuroscience, biomedical engineering, brain–machine interfaces, and cognitive science, to name but a few. This Special Issue aims to provide a forum for academic and industrial communities to present and discuss the latest theoretical and experimental results related to recent advances in neuroimaging data processing in terms of new theories, algorithms, architectures, and applications
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  • 54
    ISBN: 9783036566726 , 9783036566733
    Language: Undetermined
    Pages: 1 Online-Ressource (672 p.)
    Keywords: Medicine ; Oncology
    Abstract: This reprint covers some significant impacts in the recent research in both the private and public sectors of cancer diagnosis and therapy, in which Artificial Intelligence (AI) and Machine Learning are significant. This reprint is also a collection of forty different complex and challenging problems arranged in five groups: AI in prognosis, grading, and prediction, AI in clinical image analysis, AI models for pathological diagnosis, ML and statistical models for molecular cancer diagnostics and genetics, and AI in triage, risk stratification, and screening cancer, which are all focused on using AI in cancer diagnosis and therapy. All the necessary concepts, solutions, methodologies, and references are supplied except for some fundamental knowledge that is well-known in the general fields of AI and cancer diagnosis and therapy. The readers may, therefore, gain the main concepts of each chapter, with as little of a need as possible to refer to the concepts of the other chapters and references. The readers may hence start to read one or more chapters of the book for their own interests
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  • 55
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570457 , 9783036570440
    Language: Undetermined
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Medicine
    Abstract: This reprint, guest edited by Anne-Marie Caminade, gives an impressionist overview of the current state of the art about “Personalized and Precision Medicine”. Twenty contributions illustrate the diversity of the topic, including new approaches about cancers, neurodegenerative diseases, infectious diseases, lungs obstruction, skeletal diseases, intestinal microbiomes, new tools such as ultra-high-frequency ultrasound or non-oncological radiotherapy, and a new class of drugs (dendrimers). This reprint is an illustration of the present and future impact of Personalized and Precision Medicine on all the therapeutic domains
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  • 56
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571201 , 9783036571218
    Language: Undetermined
    Pages: 1 Online-Ressource (562 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint collected a set of papers where our section Editorial Board Members discuss key topics that typify the very best insightful and influential original articles or reviews in the “Communications” field. We expect these papers to be widely read and highly influential within the field
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  • 57
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570334 , 9783036570327
    Language: Undetermined
    Pages: 1 Online-Ressource (700 p.)
    Keywords: Medicine ; Oncology
    Abstract: Novel Anticancer Strategies (Volume II) reviews important findings and updates within the cancer therapy field of great interest to those in academic research studying the development and validation of novel anticancer approaches. The Editor invited preeminent specialists to contribute to original and review articles devoted to key areas of major progress and expectations. Key Features:Nanoparticle-based drug delivery in cancer therapy;Nanoerythrosomes;Cancer immunotherapy;Therapeutic vaccines;Oncogenic and tumor suppressive components of the cell cycle;Antimitotics in cancer clinical trials;Multifunctional enzymes as anti-cancer drug targets;Targeting undruggable proteins and non-coding RNAs;Cell-penetrating peptides;Repurposed cancer drugs in clinical trials;Circulating tumour cells
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  • 58
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567242 , 9783036567259
    Language: Undetermined
    Pages: 1 Online-Ressource (216 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: Nanocomposites have the potential for novel material properties that significantly exceed the capabilities of their individual constituent phases, thereby enabling the exploration of gaps in material property charts. In this book, we aim to provide an overview of the current state of the art, enabling the investigation of novel structural and functional material properties through better understanding and implementation of nanocomposite design. The covered properties of interest encompass the whole material usage span, starting from the structural modifications of nanocomposites by employing different synthesis routes, to assessing their microstructure-dependent mechanical properties such as strength, ductility, and high-temperature stability. Furthermore, we address the functional characteristics of nanocomposites, such as soft magnetic properties or thermoelectricity, as well as tailored property adjustment through design strategies (bioinspired design, chemical sensitivity, bio sensing). Thus, the included contributions detail methods for the synthesis, characterization, modeling, and in-depth understanding of the mechanisms governing the outstanding properties of this fascinating material class
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  • 59
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568966 , 9783036568973
    Language: Undetermined
    Pages: 1 Online-Ressource (320 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized treatment optimization. MIPD integrates mathematical models of drugs and diseases combined with individual patient characteristics (e.g., genotype, anthropometric factors, and organ function). MIPD has been highlighted as a useful tool for drug dosage selection in both the drug development process and clinical practice and it is a rapidly growing discipline that is supported by the main drug regulatory agencies. Despite the potential benefits of this methodology toward personalized medicine, its application is still limited. The Special Issue presented here includes several PKPD and PBPK models focused on improving the current state of art regarding the PK behaviour of different drugs with the aim of improving the efficacy/safety balance of these treatments and their clinical outcome; the Special Issue is intended to be of particular interest for clinical pharmacologists, pharmacometricians, and specific clinicians who routinely use the considered drugs
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036560588 , 9783036560571
    Language: Undetermined
    Pages: 1 Online-Ressource (270 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Many existing and newly constructed bridges are composed of reinforced and prestressed concrete. Advanced concrete materials play an increasingly important role in concrete bridges to facilitate the strengthening and repair of existing bridges, to facilitate a (fast) replacement solution for (part of) an existing bridge, and for the design of new challenging bridge projects. The development of advanced concrete materials and their structural applications is thus an important topic in the built environment.This reprint brings together research and practical applications from the perspective of material scientists and bridge engineers for applications to new and existing bridges
    Note: English
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570310 , 9783036570303
    Language: Undetermined
    Pages: 1 Online-Ressource (396 p.)
    Keywords: Medicine ; Oncology
    Abstract: Novel Anticancer Strategies reviews important findings and updates within the cancer therapy field, of great interest to those in academic research studying the development and validation of novel anticancer approaches. The Editor invited preeminent specialists to contribute to original and review articles devoted to key areas of major progress and expectations. Key features: Nanoparticle-based drug delivery in cancer therapy; Extracellular vesicles for anticancer drug delivery; Peptide-based drug conjugates; Cancer stem cells as a valuable target to eradicate tumor relapse; Spheroids in preclinical model for cancer research; and cancer immunotherapy
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  • 62
    ISBN: 9783036568829 , 9783036568836
    Language: Undetermined
    Pages: 1 Online-Ressource (318 p.)
    Keywords: Medicine
    Abstract: This reprint represents a collection of papers that aimed to highlight the importance of immunohistochemical findings and their role in improving the understanding of organ tissue functions. We focused our attention on farm animals because they represent not only a source of food in the supply chain, but also a source of income for breeders, a source of employment, and a primary tool in the quest for sustainable food production. To achieve this last aim, we asked authors for research that could potentially be applied to the purpose of this study, and whose results could be useful in improving farm management practices and the responsible use of natural resources. A total of 20 papers were contributed to this issue, written by 118 authors from 4 countries, and comprising 18 research articles and 2 communications articles
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  • 63
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036549231 , 9783036549248
    Language: Undetermined
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: Extreme hydrometeorological events, which cause severe impacts in terms of injuries, casualties, and socioeconomic losses, are being reported more and more frequently worldwide. Climate variability and anthropogenic changes amplify the impacts of these events. This reprint showcases studies which address challenges related to monitoring, modeling, forecasting, and assessing the impacts of hydrometeorological hazards. These studies focus on: (i) the description of recent relevant extreme hydrometeorological events, accompanied by analyses of spatiotemporal features and trends; (ii) the estimation and projection of the impacts of climate change and land-use transformations on the occurrence and severity of hydrometeorological extreme events, with associated uncertainties; (iii) the integration of remote sensing data or climate forecasts and models to provide timely warnings or reliable predictions; and (iv) the use of advanced statistical methodologies to characterize extreme hydrometeorological events, among other topics
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  • 64
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569185 , 9783036569192
    Language: Undetermined
    Pages: 1 Online-Ressource (414 p.)
    Keywords: Medicine ; Physiology
    Abstract: This reprint is about vitamin D, a molecule that can be absorbed from certain foods, such as fatty fish, which can also be produced endogenously when we expose our skin to sufficient doses of ultraviolet B radiation. When vitamin D is metabolized into 1,25(OH)2D3 (also called calcitriol), it acts as a high-affinity ligand for the transcription factor VDR, i.e., it has direct effects on gene regulation. The key physiological functions of vitamin D are the regulation of calcium homeostasis, which is essential for bone mineralization, and the modulation of the immune system by stimulating innate immunity and preventing overreactions of adaptive immunity. This reprint presents recent developments and the latest research in the fascinating broad range of today’s vitamin D biology, from evolution to systems biology
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  • 65
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571249 , 9783036571256
    Language: Undetermined
    Pages: 1 Online-Ressource (102 p.)
    Keywords: Medicine
    Abstract: The welfare of an individual could be severely affected by stressful events. Mainly for this reason, the scientific community is interested in finding specific and quantifiable characteristics which could indicate or predict specific signs of acute or chronic stress exposure. The aim of this reprint is to reflect this interest in the field of companion animal physiology. The authors engaged in publishing this reprint are experts in the multiple mechanisms involved in stress response, including the detection of behavioral and physical signs which can be measured through biological indicators of homeostasis displacement. The editors strongly believe this topic will be of interest not only to researchers in this field, but also to dog trainers, dog shelter workers and veterinary behaviorists
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  • 66
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575261 , 9783036575278
    Language: Undetermined
    Pages: 1 Online-Ressource (198 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Mangrove communities represent a coastal habitat located in the intertidal zone or brackish water of tropical and subtropical coastal areas, between 5°N and 5°S latitudes, spanning over 118 countries. The special ecological conditions of mangroves include high salinity, nutrient limitation, tidal gradients, high temperatures, excessively high light, and muddy anaerobic or sandy soil, which lead to various morphological and physiological adaptations of inhabiting species and act as an effective selector for the metabolic pathway via the generation of unique functional metabolites with highly unique chemical scaffolds and pharmaceutical application potential. In recent decades, numerous metabolites with uncommon structures and efficacious bioactivities have been discovered in mangrove-derived microorganisms, along with mangrove plants. For this reason, mangrove ecosystems have taken the limelight as an attractive biodiversity hotspot, attracting significant attention from organic chemists and pharmacologists. Additionally, many unique and novel chemical structures with a wide range of structural classes have suggested various biosynthetic origins containing novel functional genes and corresponding enzymes with unique catalytic functions. In this Special Issue, we welcome articles describing recent studies and pertinent reviews focusing on the latest and most important developments in bioactive product discovery from mangrove ecosystems and correlating structures with chemical synthesis, biosynthesis, genomic and metabolomics approaches, biological activities, and pharmaceutical mechanisms. We are now in the process of putting together a group of top researchers whose work we would like to feature in this collection, and we would like you to participate
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  • 67
    ISBN: 9783036576282 , 9783036576299
    Language: Undetermined
    Pages: 1 Online-Ressource (242 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: At present, the digital economy is creating a new approach to sustainable development. In particular, this relates to the transformation of the traditional economy via the influence of digitalization on finance management processes. The digital economy is affecting changes in resource management processes. Dynamic digital transformation processes are currently taking place and exerting influence on the shaping of new business models. Existing business models are changing, particularly in the context of their life cycle. The new economic model is rendered social factors more important in terms of creating value for people and the natural environment. Trust in financial institutions, which is also a factor in sustainable business models, is an important criterion for business research. Economic model based on the irresponsible use of natural resources have been heavily criticized for years, and societies have begun to reject business models that negatively impact the environment. The aim of this Special Issue is to present the results of research on the current trends and challenges related to the digital revolution in financial management for sustainable development, an issue that requires extensive research and analysis
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575964 , 9783036575971
    Language: Undetermined
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Fatigue and fracture are important design criteria for marine structures subjected to static and cyclic loading. In particular, the ability to ensure structural integrity under all design conditions is of the utmost importance for the safety of humans and the environment. Many efforts have been made to develop fatigue and fracture mechanics methods in recent decades; however, discrepancies between predicted and actual strength remain due to various reasons. Hence, this Special Issue aims to collect descriptions of fatigue and fracture mechanical behaviour of marine structures. Studies demonstrating novel methods (either analytical, empirical or numerical), as well as presentations of case studies or innovative test studies, were invited. This includes considerations of parameters which have a large influence on fatigue and fracture behaviour of materials, welded joints or structural components, such as loading conditions, scale effects, etc
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  • 69
    ISBN: 9783036576657 , 9783036576640
    Language: Undetermined
    Pages: 1 Online-Ressource (186 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The ongoing twin transition of the wood-based panel industry towards a green, digital, and more resilient bioeconomy is essential for a successful transformation to decarbonize the sector and implement a circular development model, transforming linear industrial value chains to minimize pollution and waste generation, and providing more sustainable growth and jobs. This green transition represents an opportunity to place the wood-based panel industry on a new path of more sustainable and inclusive growth, tackling climate change and reducing its dependence on fossil-derived raw materials, thus improving the industry’s resource efficiency and security. It provides examples of the most recent advances and technological developments in the design, production, characteristics, and current and future applications of sustainable, eco-friendly wood and wood-based composites with enhanced properties and a reduced carbon footprint. It is intended for material scientists, wood scientists, environmental scientists, graduate and postgraduate students in Wood Science and Technology, as well as wood-based panel industry professionals. In addition, the content is relevant to government authorities and stakeholders working in the domain of sustainable wood value chains, aimed at achieving Sustainable Development Goals and enhanced contribution of the forest-based sector to long-term climate change mitigation
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036572321 , 9783036572338
    Language: Undetermined
    Pages: 1 Online-Ressource (334 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: This reprint focuses on basic and applied research on fatigue and fracture processes in engineering of materials and composites. Special attention is given to understanding fracture processes from the point of view of micro and nano damage mechanisms related to material microstructure. Advanced experimental methods such as tomography, digital image correlation, high resolution electron microscopy and fractography are applied in combination with theoretical multiscale models based on finite element methods and fracture mechanics to reveal the fundamental causes of material failure
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  • 71
    ISBN: 9783036575797 , 9783036575780
    Language: Undetermined
    Pages: 1 Online-Ressource (260 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: “Soft Computing and Machine Learning in Dam Engineering” is a comprehensive, edited Special Issue that explores the latest advances in the application of soft computing and machine learning techniques to dam engineering. This reprint covers a range of topics, including dam design, construction, monitoring, and maintenance, and provides readers with a deep understanding of the theoretical foundations and practical applications of these techniques.Featuring contributions from leading experts in the field, the reprint presents a collection of 11 papers that offer insights into state-of-the-art approaches in dam engineering. The chapters cover topics such as fuzzy logic, genetic algorithms, artificial neural networks, and support vector machines, and provide practical examples of how these techniques can be applied to solve real-world dam engineering problems.Whether you are a researcher, engineer, or student in the field of dam engineering, “Soft Computing and Machine Learning in Dam Engineering” provides a valuable resource for staying up-to-date with the latest techniques and approaches in the field
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  • 72
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576756 , 9783036576749
    Language: Undetermined
    Pages: 1 Online-Ressource (230 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: This is a reprint of articles from the Special Issue published online in the open access journal Gels (ISSN 2310-2861). This reprint focuses on the modification of hydrogels and their applications in biomedical engineering, aiming to provide a reference for scholars in related fields. It mainly involves the applications of hydrogels in biomedical fields such as phantoms, wound healing, skin, cartilage, muscle, and drug loading. We believe this reprint can provide a valuable reference for scientific and technological workers in the fields of materials science, tissue engineering, biological manufacturing, biomedical engineering, and so on
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575865 , 9783036575872
    Language: Undetermined
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Mining technology & engineering
    Abstract: In this reprint, the underlying damage mechanisms of materials used under extreme conditions are explored using computer simulation and modelling methods, presenting important information to predict the lifetime of related facilities. The scope of this reprint embraces numerical work on material responses to extreme conditions, such as high-speed impact or loading, neutron or ion irradiation, and high-pressure and/or high-temperature environments. Related simulation results based on the first principle method, molecular dynamics, and finite element methods are reported. Results of various topics have been reported by papers collected in this book, for example, including fitting a better empirical potential, diffusion of atoms on surface, corrosion, interaction between different defects, elastic constants calculations, effect of hot press forming on collision toughness and energy distribution, and influence of radiation defects on the thermo-mechanical properties of UO2. Furthermore, a review about the experiments and models for the effect of strain rate on NiTi shape memory alloys (SMAs) has also been included in this reprint. These new results present new knowledge for understanding the damage mechanisms of materials under extreme conditions, which would be useful not only for researchers in these fields but also for new readers to learn about basic concepts and current research progress to better understand the response of materials under extreme conditions
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  • 74
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577432 , 9783036577425
    Language: Undetermined
    Pages: 1 Online-Ressource (180 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Energy industries & utilities
    Abstract: The remarkable explosion of wireless devices and bandwidth-consuming Internet applications has boosted the demand for wireless communications with ultra-high data rates. The wireless traffic volume is foreseen to match or even surpass the wired services by 2030, and high-precision wireless services will need to be guaranteed with a peak data rate of well beyond 100 Gbit/s, eventually reaching 1 Tbit/s. To meet the exponentially increasing traffic demand, new regions in the radio spectrum are being explored. The terahertz band, which is sandwiched between microwave frequencies and optical frequencies, is considered the next breakthrough point to revolutionize communication technology due to its rich spectrum resources. It is recognized as a promising candidate for future rate-greedy applications, such as 6G communications. At the World Radio Communication Conference 2019 (WRC-19), it was announced that the identification of frequency bands in the frequency range of 275 GHz–450 GHz is permitted for land-mobile and fixed service applications, indicating potential standardization of the low-frequency window of terahertz band for near-future wireless communications. Motivated by the potential of terahertz wireless communications, this reprint reports on recent critical technological breakthroughs in terms of broadband terahertz devices and communications, as well as novel technologies at other frequency bands that can also motivate terahertz research
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576152 , 9783036576145
    Language: Undetermined
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Medicine
    Abstract: Toll-like receptors (TLRs) represent a powerful system for the recognition and elimination of pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and other pathogens and damage-associated molecular patterns (DAMPs) released from dying cells. Typical PAMPs include bacterial cell wall components, viral pathogens, or pathogenic nucleic acids, including viral RNA and DNA. Activation of TLRs leads to the production of proinflammatory cytokines and type I interferons which are important for the induction of the host immune response against bacterial and viral infections. However, dysregulation and overstimulation can be detrimental, leading to hyper-inflammation, sepsis, and loss of tissue integrity. The involvement of TLRs in inflammation and bacterial infection has been recognized for a long time. There is an increasing number of reports demonstrating the involvement of TLR activation in a variety of viral infections, associated with protective immunity, but also immune hyper activation and even viral replication. Recent data show the involvement of TLR activation in various acute respiratory viral infections, including SARS-CoV-2 and indicate an essential role in COVID-19 pathology. It aimed to gather newest data and hypotheses regarding molecular and cellular mechanisms of TLR triggering and activation and their downstream signaling pathways by viral infections, and their correlation to immunology and pathophysiology of the associated diseases, to facilitate translational research resulting in new targets for the treatment of viral infectious diseases including COVID-19
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036557311 , 9783036557328
    Language: Undetermined
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Medicine
    Abstract: This book follows up on the previous volume focusing on the different biomarkers for neurodegenerative diseases. It includes original research works and review articles focusing on an improved understanding of disease mechanisms. It also aims to identify aspects of early therapeutic intervention for enhanced disease management. Some critical approaches include studies involving human tissue samples, mouse disease models, and different imaging techniques. These studies present the essential information necessary to address such pathological conditions in the future
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577333 , 9783036577326
    Language: Undetermined
    Pages: 1 Online-Ressource (298 p.)
    Keywords: Medicine ; Mental health services
    Abstract: Digital health, virtual assistance, and telemedicine are terms often used interchangeably to refer to remote medical assistance, monitoring and care. Several studies and insights have developed these issues, analyzing the advantages and disadvantages and successes and failures and offering reflections on the implications and issues of these technologies in the health domain. The results of these investigations are affecting the redesign of hospital and outpatient management based on digital innovation using eHealth and mHealth. During the COVID-19 pandemic, this approach made it possible to offer assistance and continue care at home, protecting patients, preserving health workers, limiting the spread of the virus, and reducing the need for hospitalization. This reprint contains contributions dealing with the development of DH during the COVID-19 pandemic. The contributions are from various experts in different fields regarding the application of digital health, which, in some cases is also integrated with artificial intelligence, including digital contact tracing, mHealth, virtual reality, mental health, physiology, and rehabilitation
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  • 78
    ISBN: 9783036577173 , 9783036577166
    Language: Undetermined
    Pages: 1 Online-Ressource (248 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Industry & industrial studies
    Abstract: Existing competitiveness between companies in the global market requires a high degree of proactivity, with an aim of reducing costs, increasing quality, and providing the market with innovative products that are in line with the natural evolution of customer demands. The concepts of the Toyota Production System, which have led to the adoption of lean manufacturing, have helped industrial managers to implement tools and practices that eliminate or substantially reduce wastes that normally exist in conventional production lines. However, the need for successive increase in flexibility necessitates a more favorable evolution with technological advancements in the programming of equipment and devices, along with the use of robotics and the integration of information throughout the product manufacturing cycle using the IoT or powerful networks. This concept, usually referred to as Industry 4.0, is in line with the principles of lean manufacturing, although it can only be supported by a true technological revolution involving remote programming of machines, integration of manufacturing processes, and real-time control of the work performed through an entire production cycle. This Special Issue showcases important contributions in the area of lean manufacturing and Industry 4.0, with innovative concepts that will certainly enthuse and strengthen readers’ knowledge
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575926 , 9783036575933
    Language: Undetermined
    Pages: 1 Online-Ressource (508 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used in the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of heart attack and other cardiovascular problems. It is therefore crucial that we continue to research the pathogenesis of arthritis and seek to discover novel modes of therapy. This reprint summarizes the themes of the 29 articles published in our Special Issue “Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0”. This reprint details important novel research discoveries that contribute to our current understanding of arthritis
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574660 , 9783036574677
    Language: Undetermined
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Medicine
    Abstract: There is growing evidence that among persons with disordered eating behavior, the identification of an “addictive-like eating” phenotype for some persons could be relevant and improve our ability to design better tailored interventions. This “addictive-like eating behavior” phenotype encompasses different terms or concepts, including “food addiction”, “eating addiction”, “compulsive eating behavior”, and “food craving”, but also applies to some persons with binge eating disorder, bulimia nervosa, anorexia nervosa, or binge eating symptoms. Although these terms may theoretically refer to different underlying causes or conceptualizations of addictive-like eating, all agree on the complex and multifaceted public health problem it represents and on the similarities it shares with other addictive disorders in terms of etiology, epidemiology, and treatment. Addictive-like eating behavior can deleteriously impact the patient’s outcome and may lead to poorer weight loss evolution, increased prevalence of co-occurring medical and/or psychiatric disorders, and/or lower quality of life. One of the key challenges for the present and future research is to better identify this subpopulation of patients exhibiting this addictive-like eating phenotype, and to identify the psychological/psychiatric factors and biological mechanisms underlying this increased vulnerability to addictive-like eating. Such preliminary knowledge is crucial for enabling the development of interventions targeting these vulnerability risk factors and, ultimately, improving patient outcomes
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575759 , 9783036575742
    Language: Undetermined
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: This reprint, edited by Prof. Gaetano Santulli, MD, PhD, collects the most up-to-date peer-reviewed scientific papers dealing with cardiovascular medicine, from basic science to pre-clinical and clinical investigations, highlighting the fundamental importance of translational medicine in the challenging quest for new therapies to cure cardiovascular disease. Indeed, cardiovascular disease is the leading cause of death worldwide, and the search for novel mechanisms and therapeutics is desperately needed. Therefore, both basic and translational studies in the cardiovascular field represent a paramount strategy to identify novel therapeutic targets and improve the quality of life of patients with cardiovascular disorders
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573090 , 9783036573083
    Language: Undetermined
    Pages: 1 Online-Ressource (292 p.)
    Keywords: Medicine
    Abstract: This reprint describes how lifestyle changes can impact the incidence and progression of chronic non-communicable diseases. In this context, regular physical activity and heathy nutritional habits are very important. Moreover, natural bioactive compounds could represent a new adjuvant therapy in the clinical management of these pathological conditions
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574165 , 9783036574172
    Language: Undetermined
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Medicine
    Abstract: Agricultural products such as fruit, vegetables, and cereal are believed to be some of the most crucial sources of certain phytonutrients necessary for humans, such as vitamins, dietary fibers, and minerals. However, agricultural products are prone to quality deterioration during storage under ambient temperatures. Currently, the annual post-harvest loss rate of agricultural products can reach up to 20–30%. Owing to their perishable nature, the development of processing and preservation technologies for agricultural products is an important research topic closely associated with the national economy and people’s livelihoods that has attracted ever-increasing attention. In view of the prominent issues of high energy consumption, high costs, serious pollution, and low-quality properties in agricultural product manufacturing, our journal mainly focuses on research articles on novel techniques and the underlying mechanisms of the processing, preservation, and quality control of agricultural products, so as to promote the upgrading and updating of the agricultural product industry
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    ISBN: 9783036576695 , 9783036576688
    Language: Undetermined
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: The first three papers describe research activities about poly(lactic acid) (PLA)-based blends and their composites with wheat bran that were carried out under the framework of the BIONTOP project ("Novel Packaging Films and Textiles with Tailored End of Life and Performance Based on Bio-based Copolymers and Coatings", 837761) funded by the European Commission BBI-JU program. The melt fluidity, morphological, thermo-mechanical, creep and fracture properties of these promising biodegradable materials were considered and discussed. The reprint then includes two contributions (a review and a research article) written in the contest of ECOFUNCO project ("ECO Sustainable Multi FUNctional Biobased COATings with Enhanced Performance and End of Life Options", 837863) funded by the European Commission BBI-JU program. The review explores possible innovations in the field of solid and liquid biobased coatings, whereas the research article examines the modification of paper tissues with biobased additives for sustainable personal care applications. A research paper on the production of PLA-based composites to valorize hazelnut shell powder, which represents an agro-food waste, is also included in the reprint. Moreover, the reprint presents research papers investigating different biobased materials for environmental depollution, including hydrogel-based, bacterial cellulose-based and biochar-based materials. Finally, a research paper on the behavior of natural rubber during aging is presented
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577661 , 9783036577678
    Language: Undetermined
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Medicine ; Surgery
    Abstract: We are in the modern era of innovations, technological developments and minimisation in the field of urology. While laparoscopy and robotic surgery have revolutionised pelvic and upper tract oncology, there is continuous evolution and increasing use of these in the field of benign conditions and paediatric urology. As lasers have changed endourology, new minimally invasive surgical techniques (MISTs) have given a new meaning to benign prostate hyperplasia (BPH) surgery. Oncological developments for prostate cancer now include treatments such as robotic prostatectomy, brachytherapy, radiotherapy, cryotherapy and HIFU. Robotic partial nephrectomy and cryotherapy have changed the face of renal cancer. While robotic cystectomy is also gaining popularity for muscle-invasive bladder cancer, new concepts of En-bloc resection of bladder cancer are emerging and being increasingly adopted. MISTs for BPH include laser (Holmium, thulium and green light), water-based treatments (Rezum, Aquablation) and other minimally invasive procedures such as prostate artery embolisation (PAE), TIND and Urolift. There is increasing emphasis on the role of suction in endourological procedures, while the quest for better intrarenal pressure and temperature monitoring continues. The use of Thulium fibre laser (TFL), Moses technology and small disposable ureteroscopes all help in pushing the boundaries of ureteroscopy (URS) and percutaneous nephrolithotomy (PCNL) procedures. These new technological developments have led to improvements in patients’ quality of life (QoL), shorter hospital stays and reductions in complication rates
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575308 , 9783036575315
    Language: Undetermined
    Pages: 1 Online-Ressource (578 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: The aim of this second Eng Special Issue is to collect experimental and theoretical re-search relating to engineering science and technology. The general topics of Eng are as follows: electrical, electronic and information engineering; chemical and materials engineering; energy engineering; mechanical and automotive engineering; industrial and manufacturing engineering; civil and structural engineering; aerospace engineering; biomedical engineering; geotechnical engineering and engineering geology; and ocean and environmental engineering. Therefore, the following editorial is a selection of representative works of these topics
    Note: English
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  • 87
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577876 , 9783036577869
    Language: Undetermined
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Medicine
    Abstract: Electrospinning can be used to prepare nanofibrous membranes from diverse polymers. The large surface-to-volume ratio makes them suitable for diverse fields of applications, from filters to catalysts to tissue engineering.Here, we search for the latest developments dealing with nanofiber mats for biomedicine. From wound healing to slow release, and from tissue engineering to stem cell differentiation, nanofibrous membranes can be found in a broad range of biomedical applications. For these utilizations, their chemical as well as physical properties are important, such as hydrophobicity, fiber morphology, membrane porosity, mechanical strength, etc. This Special Issue focuses on nanofibrous membranes for biomedical applications, measuring and optimizing the correlated membrane properties. It covers the full range from basic research on new materials and producing novel electrospun structure to drug release to cell growth on nanofiber mats
    Note: English
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  • 88
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577913 , 9783036577906
    Language: Undetermined
    Pages: 1 Online-Ressource (316 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: Advanced manufacturing technology and systems cover a broad scope involving manufacturing processes, machine tool design, system optimization, smart and flexible manufacturing, theoretical study and metrology. This reprint comprises 19 original papers concerning recent advances in the research and development of AMTSs. Specifically, there are many research fields that are covered: machining processes (six papers), micro-/nano-precision fabrication (four papers), and system optimization (eight papers), in addition to one review
    Note: English
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  • 89
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575988 , 9783036575995
    Language: Undetermined
    Pages: 1 Online-Ressource (246 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: In the treatment of acute stroke, thrombolysis and thrombectomy have proven to be highly effective. Many patients have seen significant improvement after reperfusion therapy. This reprint aims to address current knowledge gaps and promote advancements in the use of thrombolysis and thrombectomy for the treatment of acute ischemic stroke
    Note: English
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  • 90
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577081 , 9783036577098
    Language: Undetermined
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Medicine
    Abstract: The articles discussed in this reprint show the potential health benefits of nutraceuticals, which are products containing bioactive compounds that can prevent and treat chronic diseases. This book explores various functional ingredients, including plant-derived products, mushrooms, microalgae, and goji berries, for their therapeutic, hypoallergenic, and sporting purposes. The study of the gut microbiome and its interactions with dietary components is also discussed. Additionally, the importance of sustainable and environmentally friendly practices in the food industry also stands out. As consumers seek out natural and functional food products, continued research on and the development of nutraceuticals will be critical in promoting healthy aging and addressing chronic diseases
    Note: English
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  • 91
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575483 , 9783036575490
    Language: Undetermined
    Pages: 1 Online-Ressource (220 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: In recent years, ironmaking and steelmaking have witnessed the incorporation of various new processes and technologies that can be operated and organized in different combinations depending on the properties of raw materials and the required quality of the final products. Indications from the steel industry and local and global government institutions suggest that the breakthrough technologies for decarbonization will be based on new fuels and energy vectors. For CO2-lean process routes, three major solutions have been identified: decarbonizing, whereby coal would be replaced by hydrogen or electricity in the hydrogen reduction or electrolysis of iron ore processes; the introduction of CCS technology; and the use of sustainable biomass. Today, hydrogen-based steelmaking is a potential low-carbon and economically attractive route, especially in countries where natural gas is cheap. By considering systems for increasing energy efficiency and reducing the environmental impact of steel production, CO2 emissions may be greatly reduced by hydrogen-based steel production if hydrogen is generated by means of carbon-free and renewable sources. Currently, the development of the hydrogen economy has received a great deal of attention in that H2 is considered a promising alternative to replace fossil fuels. Based on hydrogen, the “hydrogen economy” is a promising clean energy carrier for decarbonized energy systems if the hydrogen used is produced from renewable energy sources or coupled with carbon capture and storage (CCS) or nuclear energy
    Note: English
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  • 92
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574684 , 9783036574691
    Language: Undetermined
    Pages: 1 Online-Ressource (316 p.)
    Keywords: Technology: general issues ; History of engineering & technology
    Abstract: This reprint presents a collection of original research and survey articles that tackle the practical challenges in large-scale and rapid deployment of sensors for diverse applications as well as the resulting Big Data processing. The complexity of the generated data ranges from large-scale sensor networks to smartphone-enabled citizen sensing data from social networks and personal health devices, which requires advanced data processing, mining and fusion methods. Solutions listed in this book include those that address issues of the interoperability of IoT solutions and data fragmentation through crawling, indexing and searching IoT data sources and the predictive maintenance of sensors. Social networks are also in scope, through a visualisation system for the analysis of anomalies in social graphs, detecting context-aware sociability patterns and assessing the effectiveness of fine tuning and pretrained word embedding in generating interpretable topics from short texts in social networks. Applications in scope include smart tourism, fall detection through personal health sensors and an energy management expert assistant
    Note: English
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  • 93
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575612 , 9783036575605
    Language: Undetermined
    Pages: 1 Online-Ressource (318 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Energy industries & utilities
    Abstract: "Advances in UAV Detection, Classification and Tracking" is a comprehensive book that explores the latest techniques and advancements in unmanned aerial vehicle (UAV) detection, classification, and tracking. As UAV technology continues to evolve and become more accessible, there is a growing need for effective methods to detect, identify, and track these devices in various scenarios. This reprint provides a thorough overview of the state-of-the-art approaches for UAV detection, classification, and tracking, covering both theoretical and practical aspects.The reprint begins by introducing the basics of UAVs and their various applications, followed by a detailed overview of the challenges associated with UAV detection, classification, and tracking. The authors then present the latest techniques and algorithms used in the field, including machine-learning-based approaches, computer vision techniques, and sensor fusion techniques. The reprint also covers the challenges of real-world applications, such as dealing with occlusions, sensor noise, and environmental factors.With contributions from leading experts in the field, "Advances in UAV Detection, Classification and Tracking" is an essential resource for researchers, engineers, and practitioners working on UAV detection, classification, and tracking. It is also a valuable reference for graduate students and anyone interested in the latest advancements in this rapidly evolving field
    Note: English
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  • 94
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577531 , 9783036577524
    Language: Undetermined
    Pages: 1 Online-Ressource (178 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Environmental science, engineering & technology
    Abstract: Major concerns regarding health and the environment are at the heart of the United Nations Educational, Scientific and Cultural Organization's Sustainable Development Goals. Now more than ever, humanity is called upon to take action to protect the environment and public health. The environment in which we live is the most vital factor for our health and well-being. Human activities have significant impacts on the atmosphere, lithosphere, hydrosphere, biosphere, and even outer space. Biological, chemical, and physical risk factors are part of our everyday lives, and scientific research continuously faces challenges to understand and mitigate these interactions to make life on Earth more sustainable. The sustainability of human societies and the biodiversity that supports them requires the responsible supervision of natural resources, including the development of technologies and regulations
    Note: English
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  • 95
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575421 , 9783036575438
    Language: Undetermined
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Conservation of buildings & building materials
    Abstract: The thirty-plus years of progress in the field of structural health monitoring (SHM) have had a huge impact on our everyday lives. Be it for the monitoring of fixed- and rotary-wing aircrafts, for the preservation of the cultural and architectural heritage, or for the predictive maintenance of long-span bridges or wind farms, SHM has shaped the framework of many engineering fields. Given the current state of quantitative and principled methodologies, it is nowadays possible to rapidly and consistently evaluate the structural safety of industrial machines, modern concrete buildings, historical masonry complexes, etc., to test their capability and to serve their intended purpose. However, old unsolved problems as well as new challenges exist. Furthermore, unprecedented conditions, such as stricter safety requirements and ageing civil infrastructure, pose new challenges. Therefore, the second volume of this Special Issue series gathers the main contributions of academics and practitioners in civil, aerospace, and mechanical engineering to provide a common ground for structural health monitoring in dealing with old and new aspects of this ever-growing research field
    Note: English
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  • 96
    ISBN: 9783036576008 , 9783036576015
    Language: Undetermined
    Pages: 1 Online-Ressource (368 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Mechanical engineering & materials
    Abstract: The Special Issue "Fatigue and Fracture of Metals and Alloys: Numerical and Experimental Study" includes 19 articles covering problems in fatigue and fracture mechanics from different parts of the scientific world. The issue includes articles presenting theoretical, numerical, statistical and experimental approaches to fatigue life estimation. The influence of technological processes, state of stress, or the environment on steel and aluminum alloys is presented. The subjects of the articles of interest, as they present solutions to common practical problems in the industry
    Note: English
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  • 97
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574882 , 9783036574899
    Language: Undetermined
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Materials science
    Abstract: “Material Analysis in Cultural Heritage” describes the application of modern analytical techniques in the studies of selected historical materials, their properties, and processes they undergo. The topics include glass and ceramics, metal preservation, functionality and testing of historic and modern building materials, origins of specific stones, decomposition of painting pigments, and the construction of historic violins
    Note: English
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  • 98
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566085 , 9783036566092
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Parallel Title: Erscheint auch als Measurement uncertainty
    Keywords: Technology: general issues ; History of engineering & technology ; Dichte ; Fuzzy-Zufallsvariable ; T-Norm ; Kalman-Filter ; Messbrücke ; Kalibrieren ; Synchronisierung ; Digitalisierung ; Datenauswertung ; Datenübertragung ; Unsicherheit ; Direct simulation Monte-Carlo-Methode ; Python ; Modellierung ; Wahrscheinlichkeitstheorie ; Spektralanalyse ; Dimension 3 ; Punktwolke
    Abstract: This reprint focuses on a very important topic in metrology, which is represent by measurement uncertainty. Any good metrologist or scientist in engineering knows that no measurement makes sense without an associated uncertainty value: without an uncertainty value, no decision can be taken; no comparisons can be made; no conformity can be assessed. Any decision, comparison or conformity assessment made without considering the measurement uncertainty affecting the measurement value is completely useless and meaningless. Stated that, it becomes very clear that uncertainty in measurement plays indeed a very important rule in our everyday life. This is the reason why there is a great need to have a fruitful academic and scientific discussion on this topic. We have been speaking about measurement uncertainty for less than 30 years, since the concept of “measurement uncertainty” has been introduced in 1995 by the “Guide to the expression of uncertainty in measurement” (GUM). Thirty years seems to be many, but still the concept of measurement uncertainty has not been spread worldwide and the GUM is a document that is not known everywhere. On the other hand, this document should be considered not only in academic scenario, but also in any technical and industrial scenario, where it is pivotal to know the meaning of measurement uncertainty, identify the uncertainty contributions and know how these contributions affect the final measurement result
    Note: English
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  • 99
    ISBN: 9783036576022 , 9783036576039
    Language: Undetermined
    Pages: 1 Online-Ressource (382 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Energy industries & utilities
    Abstract: This reprint focuses on challenging issues in the field of AI-based image and video processing and recognition, including the topics of AI-based image processing, understanding, recognition, compression, and reconstruction; AI-based video processing, understanding, recognition, compression, and reconstruction; computer vision based on AI; AI-based biometrics; AI-based object detection and tracking; approaches that combine AI techniques and conventional methods for image and video processing and recognition; explainable AI (XAI) for image and video processing and recognition; generative adversarial network (GAN)-based image and video processing and recognition; and approaches that combine AI techniques and blockchain methods for image and video processing and recognition
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  • 100
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036557014 , 9783036557021
    Language: Undetermined
    Pages: 1 Online-Ressource (308 p.)
    Keywords: Technology: general issues ; History of engineering & technology ; Transport technology & trades
    Abstract: This book focuses on advanced techniques to reduce the impact of the transport sector and, more specifically, of Spark-Ignition (SI) Internal Combustion Engines (ICEs) on atmospheric air pollution and climate change. Hybrid vehicles represent the most suitable option for addressing these issues in the medium term, since hybridization allows us to overcome the major disadvantages of ICEs, electric units, and energy storage devices and merge their respective benefits. In this scenario, ICEs will remain the core component of automotive propulsion systems in the years to come. Of course, further efforts to improve the efficiency and reduce the pollutant and CO2 emissions of ICEs are necessary
    Note: English
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