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  • Online Resource  (484)
  • Undetermined  (484)
  • 2020-2024  (482)
  • 1990-1994  (2)
  • Medicine  (461)
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  • 1
    ISBN: 9783839466049 , 9783837666045
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Series Statement: Gesundheit, Kommunikation und Gesellschaft
    Keywords: Social work ; Medicine: general issues ; Soziale Arbeit ; Medizinische Rehabilitation ; Wirkung ; Gesundheit ; Pflege ; Reha ; Zusammenarbeit ; Teilhabe ; Körper ; Medizin ; Sozialarbeit ; Public Health ; Social Work ; Health-related Rehabilitation ; Effect ; Health ; Care ; Cooperation ; Participation ; Body ; Medicine
    Abstract: Soziale Arbeit ist ein wichtiger Teil der medizinischen Rehabilitation. Die Ausgestaltung ihrer Leistungen und ihre potentielle Wirkung blieben bislang allerdings unklar. An dieser Stelle setzen die Autor*innen an und präsentieren die Ergebnisse des Forschungsprojekts SWIMMER: Im Rahmen eines qualitativen Forschungsprojekts wurde die sozialarbeiterische Praxis von Sozialdiensten medizinischer Reha-Einrichtungen untersucht und ein Wirkmodell der Sozialen Arbeit in diesem Bereich entwickelt. Die vergleichende Darstellung der Resultate richtet sich sowohl an Sozialarbeiter*innen als auch an Verantwortliche in den Reha-Einrichtungen, die ihre eigene Praxis reflektieren und einen tieferen Einblick in gängige Arbeitsstrukturen der Sozialdienste erhalten wollen
    Note: German
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  • 2
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : Nomos Verlagsgesellschaft mbH & Co. KG
    ISBN: 9783748935865
    Language: Undetermined
    Pages: 1 Online-Ressource
    Keywords: European law ; ÖFOS 2012 -- SOCIAL SCIENCES (5) -- Law (505) -- Law (5050) -- European law (505003) ; International law ; ÖFOS 2012 -- SOCIAL SCIENCES (5) -- Law (505) -- Law (5050) -- International law (505029) ; Laws of specific jurisdictions and specific areas of law ; Thema Subject Codes -- Law (L) -- Laws of specific jurisdictions and specific areas of law (LN) ; Europe ; Thema Subject Codes -- Place qualifiers (1) -- Europe (1D) ; EU soft law ; enforcement of EU law ; Treaty infringement procedure ; competences ; agencies ; legal protection ; Europarecht ; ÖFOS 2012 -- SOZIALWISSENSCHAFTEN (5) -- Rechtswissenschaften (505) -- Rechtswissenschaften (5050) -- Europarecht (505003) ; Völkerrecht ; ÖFOS 2012 -- SOZIALWISSENSCHAFTEN (5) -- Rechtswissenschaften (505) -- Rechtswissenschaften (5050) -- Völkerrecht (505029) ; Recht bestimmter Jurisdiktionen und bestimmter Rechtsgebiete ; Thema Klassifizierung -- Recht (L) -- Recht bestimmter Jurisdiktionen und bestimmter Rechtsgebiete (LN) ; Europa ; Thema Klassifizierung -- Geographische Qualifier (1) -- Europa (1D) ; EU soft law ; EU-Rechtsdurchsetzung ; Vertragsverletzungsverfahren ; Kompetenzen ; Agenturen ; Rechtsschutz
    Abstract: This book is dedicated to the role of soft law in the enforcement of EU law vis-à-vis the Member States. Apart from the Treaty infringement procedure, there is an increasing number of procedures, mostly laid down in secondary law, by which the EU – often availing itself of soft law – aims at ensuring Member States’ compliance with EU law. These procedures are compared with each other, also with respect to their use of soft law, and their conformity with primary law is examined
    Abstract: Diese Arbeit widmet sich der Rolle des soft law bei der Durchsetzung von Unionsrecht gegenüber den Mitgliedstaaten. Neben dem Vertragsverletzungsverfahren gibt es immer mehr, v.a. sekundärrechtlich geregelte Verfahren, mit denen die EU Rechtsdurchsetzung gegenüber den Mitgliedstaaten betreibt, oft auch mittels unverbindlicher Akte. Diese Verfahren werden, auch hinsichtlich der Verwendung von soft law, miteinander verglichen und auf ihre Primärrechtskonformität hin überprüft
    Note: English
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  • 3
    ISBN: 9783111075372 , 9783110789249
    Language: Undetermined
    Pages: 1 Online-Ressource (560 p.)
    Series Statement: Verflechtung - Aushandlung - Opazität
    Keywords: Wandbild ; Fotografie ; USA ; Muralismus ; Fototapete ; Fotofresko ; Entangled history ; Diego Riviera ; El Lissitzky ; Edward Steichen ; Margaret Bourke-White ; murals ; photography ; photo wallpaper ; entangled histories ; photo fresco ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999::3MPQ Later 20th century c 1950 to c 1999 ; thema EDItEUR::A The Arts::AF The Arts: art forms::AFC Paintings and painting ; thema EDItEUR::A The Arts::AJ Photography and photographs
    Abstract: Das fotografische Wandbild, das sogenannte photomural, wurde in den USA der 1930er-­Jahre zu einem Inbegriff nationaler Kunst und dabei als Gegenentwurf zum mexikanischen Muralismus positioniert. Johanna Spanke untersucht erstmals, inwiefern der Aufstieg des photomural als das Resultat eines Aushandlungsprozesses zwischen Mexiko und den USA begrif­fen werden kann, bei dem nicht nur nationale Identitätskonstruktionen und Modernitätsdiskurse eine Rolle spielen, sondern auch eine Medienkonkurrenz verhandelt wird. Der Band leistet einen wichtigen Beitrag zu verflechtungs­geschichtlichen Perspektiven auf die US-­amerikanische Kunstgeschichte, der intermediale und transnationale Aushandlungen, aber auch Gender­ Aspekte zentral in den Vordergrund rückt. Erste Studie zu einem vergessenen fotografischen Medium Vorgeschichte der Fototapete Ein bislang unbekanntes Kapitel der US-amerikanischen Kunst ; Das fotografische Wandbild, das sogenannte photomural, wurde in den USA der 1930er-­Jahre zu einem Inbegriff nationaler Kunst und dabei als Gegenentwurf zum mexikanischen Muralismus positioniert. Johanna Spanke untersucht erstmals, inwiefern der Aufstieg des photomural als das Resultat eines Aushandlungsprozesses zwischen Mexiko und den USA begrif­fen werden kann, bei dem nicht nur nationale Identitätskonstruktionen und Modernitätsdiskurse eine Rolle spielen, sondern auch eine Medienkonkurrenz verhandelt wird. Der Band leistet einen wichtigen Beitrag zu verflechtungs­geschichtlichen Perspektiven auf die US-­amerikanische Kunstgeschichte, der intermediale und transnationale Aushandlungen, aber auch Gender­ Aspekte zentral in den Vordergrund rückt. Erste Studie zu einem vergessenen fotografischen Medium Vorgeschichte der Fototapete Ein bislang unbekanntes Kapitel der US-amerikanischen Kunst ; The photographic wall-mounted work, the so-called photomural, became an epitome of the USA’s national art in the 1930s; also as a counter-design to Mexican muralism. For the first time, Johanna Spanke analyzes the extent to which the rise of the photomural can be seen as emerging from a process of mediation between Mexico and the United States; one in which national identity constructs and discourses of modernity played a part, as well as negotiated competition between media. This publication makes an important contribution to perspectives on historical entanglements in U.S. art history, bringing to the fore intermedial and transnational debates, as well as gender-related factors. First study concerning a forgotten photographic medium Prehistory to the photo wallpaper A previously unfamiliar chapter in US American art
    Note: German
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  • 4
    ISBN: 9783031393556 , 9783031393549
    Language: Undetermined
    Pages: 1 Online-Ressource (810 p.)
    Series Statement: Health Informatics
    Keywords: Medical equipment and techniques ; Information technology: general topics ; Nursing and ancillary services ; Computer science ; Biology, life sciences ; Public health and preventive medicine ; Predictive analytics ; Artificial intelligence ; Medicine ; Machine learning ; Causal discovery ; Causal inference ; Genomics ; Medical knowledge discovery ; Clinical risk models ; Clinical risk stratification
    Abstract: This open access book provides a detailed review of the latest methods and applications of artificial intelligence (AI) and machine learning (ML) in medicine. With chapters focusing on enabling the reader to develop a thorough understanding of the key concepts in these subject areas along with a range of methods and resulting models that can be utilized to solve healthcare problems, the use of causal and predictive models are comprehensively discussed. Care is taken to systematically describe the concepts to facilitate the reader in developing a thorough conceptual understanding of how different methods and resulting models function and how these relate to their applicability to various issues in health care and medical sciences. Guidance is also given on how to avoid pitfalls that can be encountered on a day-to-day basis and stratify potential clinical risks. Artificial Intelligence and Machine Learning in Health Care and Medical Sciences: Best Practices and Pitfallsis a comprehensive guide to how AI and ML techniques can best be applied in health care. The emphasis placed on how to avoid a variety of pitfalls that can be encountered makes it an indispensable guide for all medical informatics professionals and physicians who utilize these methodologies on a day-to-day basis. Furthermore, this work will be of significant interest to health data scientists, administrators and to students in the health sciences seeking an up-to-date resource on the topic
    Note: English
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  • 5
    Online Resource
    Online Resource
    Cambridge : Open Book Publishers
    ISBN: 9781805111016 , 9781805111023 , 9781805111047 , 9781805111078 , 9781805111061
    Language: Undetermined
    Pages: 1 Online-Ressource (406 p.)
    Keywords: Literature & literary studies ; Literature: history & criticism ; Literary theory ; USA ; Biblical studies & exegesis ; Walt Whitman;King James Bible;Nineteenth-Century American poetry;Free verse;'Leaves of Grass';Literature scholarship
    Abstract: In exploring the seminal works of Walt Whitman, the great American poet, many commentators have acknowledged the underlying influence of The King James Bible. However, a study has yet to elucidate the precise manner in which the Bible has shaped Whitman’s poetic style. This is the deficit that F. W. Dobbs-Allsopp seeks to address in his new piece of literary scholarship: 'Divine Style: Walt Whitman and the King James Bible'. Dobbs-Allsopp, Professor of Old Testament at Princeton Theological Seminary, explicitly approaches Whitman from the perspective of a biblical scholar. Utilising his wealth of expertise in this field, he constructs a compelling, erudite and methodical argument for the King James Bible’s importance in the evolution of Whitman’s style – from his signature long lines to the prevalence of parallelism and tendency towards parataxis in his works. 'Divine Style' focuses on Whitman’s output in the years preceding the release of his 1855 opus 'Leaves of Grass' through the general period of the book’s first three editions. In this, Dobbs-Allsopp’s exploration of the period is exhaustive – covering not just Leaves of Grass but recently recovered notebooks, newly digitised manuscripts and additions to the corpus, such as the novel 'Life and Adventures of Jack Engle'. This is a work of careful, detailed scholarship, offering an authoritative commentary that will be a valuable resource for students of Whitman, biblical scholars and scholars of literature more generally
    Note: English
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  • 6
    ISBN: 9783839471906 , 9783837671902
    Language: Undetermined
    Pages: 1 Online-Ressource (364 p.)
    Series Statement: Medical Humanities
    Keywords: Social, group or collective psychology ; Psychoanalytical theory (Freudian psychology) ; Medicine: general issues ; Biographie ; Erzählung ; Lebensgeschichte ; Wiedererzählung ; Interview ; Narratives Interview ; Identität ; Lebensgestaltung ; Medizin ; Therapie ; Krankheit ; Selbsterzählung ; Kultur ; Sprache ; Sozialpsychologie ; Psychoanalyse ; Kulturwissenschaft ; Biography ; Narrative ; Retelling ; Narrative Interview ; Identity ; Life Design ; Medicine ; Therapy ; Illness ; Culture ; Language ; Social Psychology ; Psychoanalysis ; Cultural Studies
    Abstract: Wie erzählen Menschen ihre Lebensgeschichten? Und wie verändern sich diese Erzählungen im Laufe der Zeit? Shevek K. Selbert widmet sich an der Schnittstelle von Biographieforschung, Psychologie und Erzählforschung vollumfänglich wiederholten biographisch-narrativen Interviews, die im Abstand von zehn Jahren geführt wurden. Als Pionierarbeit qualitativer Längsschnittforschung entwickelt er Methoden, um die Erzählversionen miteinander zu vergleichen - und bietet einen einzigartigen Einblick in die Dynamik sowie die (auch therapeutische) Bedeutung von Selbsterzählungen für die Identitätsbildung und die Lebensgestaltung
    Note: German
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  • 7
    ISBN: 9783839471517 , 9783837671513
    Language: Undetermined
    Pages: 1 Online-Ressource (286 p.)
    Series Statement: 1800 | 2000. Kulturgeschichten der Moderne
    Keywords: European history ; Social & cultural history ; History: theory & methods ; Grenze ; Zeitgeschichte ; Moderne ; 20. Jahrhundert ; 21. Jahrhundert ; Ideologie ; Gewalt ; Identität ; Wissen ; Raum ; Liminalität ; Gesellschaft ; Politik ; Normsetzung ; Europa ; USA ; Kulturgeschichte ; Europäische Geschichte ; Geschichtstheorie ; Geschichte des 20. Jahrhunderts ; Geschichtswissenschaft ; Border ; Contemporary History ; Modernity ; 20th Century ; 21st Century ; Ideology ; Violence ; Identity ; Knowledge ; Space ; Liminity ; Society ; Politics ; Standardization ; Europe ; Cultural History ; European History ; Theory of History ; History of the 20th Century ; History
    Abstract: Grenzen strukturieren nicht nur die Ordnung von Landschaft und Herrschaft, sondern auch von Gesellschaft. Als soziale Konstrukte vereindeutigen sie Zustände, öffnen aber auch Räume für Aushandlungen und Überschreitungen. In der Moderne dienten praktische und metaphorische »Grenzgänge« dazu, Beziehungen, die Verhältnisse gesellschaftlicher Teilsysteme und die Reichweite von Normen zu klären. Die Beiträger*innen schauen auf die Denkfigur des »Grenzgangs«, die es ermöglicht, zentrale Fragen moderner Gesellschaften zusammenzudenken: Gewaltvolle Identitätskämpfe, der Umgang mit funktionaler Differenzierung und mit der Fragilität von Werten und Wissen offenbaren sich als Praktiken, mit denen Grenzen gezogen, überquert oder ausgehandelt wurden
    Note: German
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  • 8
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594323 , 9783036594330
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Though the number of infants born with heart disease each year is relatively small (approximately 1% of the population), it is still a substantial issue worthy of investigation, which is why this Special Issue focuses on congenital heart disease in both children and adults. Advances in the treatment of such malformations have led to increased life spans for this population. Consequently, today, most patients treated for congenital heart disease are adults. The purpose of this Special Issue is to deal with the latest developments in the care of the fetus, infants and children, and how these patients should be treated, as well as to describe the results of follow-ups and the potential special needs of adults with congenital heart disease
    Note: English
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  • 9
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591988 , 9783036591995
    Language: Undetermined
    Pages: 1 Online-Ressource (218 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: Sudden cardiac death (SCD) affects more than four million patients per year worldwide, and accounts for up to 50% of all cardiovascular deaths. Related to the improved treatment options for cardiovascular diseases during the past several decades (e.g., improved guideline adherence to pharmacotherapies, increasing supply with cardiac devices, and better revascularization strategies), the characteristics of patients presenting with SCD have significantly changed, making risk prediction for SCD even more complex. The present Special Issue reprint addresses the prognostic impact of patients’ characteristics (such as body mass index), airway and ventilation management in patients needing cardiopulmonary resuscitation, and the prognostic value of a targeted ambulance treatment quality improvement programme. Furthermore, the prognostic value of blood-derived biomarkers and cardiac pharmacotherapies for the prevention of SCD was investigated
    Note: English
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  • 10
    ISBN: 9783036592640 , 9783036592657
    Language: Undetermined
    Pages: 1 Online-Ressource (270 p.)
    Keywords: Medicine
    Abstract: Otorhinolaryngology and head and neck specialists worldwide face an increasing incidence and prevalence of various pathologies, some of the cases neglecting the evolution of their condition during the period of COVID-19 pandemics, thus aggravating their evolution. This Special Issue contains reviews and selected rare case series to update the protocols of ENT and allied specialists worldwide. The aim was to present an interdisciplinary point of view of the numerous branches of pathology that form the otorhinolaryngology specialty
    Note: English
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  • 11
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036597645 , 9783036597652
    Language: Undetermined
    Pages: 1 Online-Ressource (528 p.)
    Keywords: Medicine and Nursing ; Neurology and clinical neurophysiology ; Medicine
    Abstract: undefined
    Note: English
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  • 12
    ISBN: 9783111338668 , 9783111338866 , 9783111338545
    Language: Undetermined
    Pages: 1 Online-Ressource (366 p.)
    Series Statement: Studia Linguistica Germanica
    Keywords: Linguistics ; Bilingualism and multilingualism ; Historical and comparative linguistics ; Mehrsprachigkeit ; Sprachkontakt ; Sprachgeschichte ; Europa ; Multilingualism ; language contact ; linguistic history ; Europe
    Abstract: Die Erscheinungsformen und linguistischen Effekte von Mehrsprachigkeit sind nicht nur regional oft äußerst unterschiedlich, sondern auch historisch divers und veränderlich. Die Beiträge dieses Sammelbandes haben Mehrsprachigkeitsszenarien in der Geschichte Europas im Fokus und vermitteln einen Eindruck davon, wie der Alltag von Europäerinnen und Europäern in unterschiedlichen Epochen, Gebieten oder auch Institutionen von Mehrsprachigkeit geprägt war. Der Band präsentiert verschiedene Perspektiven auf die Erforschung historischer Mehrsprachigkeit an der Schnittstelle von Sprachkontaktforschung und historischer Soziolinguistik. Er richtet sich damit an ein breites Publikum mit Interesse an historischer Sprachwissenschaft und Mehrsprachigkeitsforschung. ; Die Erscheinungsformen und linguistischen Effekte von Mehrsprachigkeit sind nicht nur regional oft äußerst unterschiedlich, sondern auch historisch divers und veränderlich. Die Beiträge dieses Sammelbandes haben Mehrsprachigkeitsszenarien in der Geschichte Europas im Fokus und vermitteln einen Eindruck davon, wie der Alltag von Europäerinnen und Europäern in unterschiedlichen Epochen, Gebieten oder auch Institutionen von Mehrsprachigkeit geprägt war. Der Band präsentiert verschiedene Perspektiven auf die Erforschung historischer Mehrsprachigkeit an der Schnittstelle von Sprachkontaktforschung und historischer Soziolinguistik. Er richtet sich damit an ein breites Publikum mit Interesse an historischer Sprachwissenschaft und Mehrsprachigkeitsforschung
    Note: German
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  • 13
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036597386 , 9783036597393
    Language: Undetermined
    Pages: 1 Online-Ressource (342 p.)
    Keywords: Medicine ; pregnancy ; fetus prenatal care ; high-risk ; pathology
    Abstract: This reprint includes studies on diagnosing, evaluating and managing the pathologies diagnosed during pregnancy. The information provided in these pages is helpful for specialists in obstetrics and gynaecology but also for other medical specialities involved in treating pregnant women with associated pathologies. Studying the articles in the reprint could contribute to improving case management
    Note: English
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  • 14
    Online Resource
    Online Resource
    Bielefeld : transcript Verlag
    ISBN: 9783839470510 , 9783837670516
    Language: Undetermined
    Pages: 1 Online-Ressource (158 p.)
    Series Statement: Science Studies
    Keywords: Universities ; Impact of science & technology on society ; Medicine: general issues ; Universität ; Bildung ; Studium ; Wissenschaft ; Führung ; Lehre ; Forschung ; Wissenschaftssoziologie ; Medizin ; Bildungsforschung ; Hochschule ; University ; Education ; Courses ; Science ; Leadership ; Teaching ; Research ; Sociology of Science ; Medicine ; Educational Research
    Abstract: Die Universität ist die größte Forschungs- und Bildungsorganisation unserer Gesellschaft und bildet dennoch einen weißen Fleck in der öffentlichen Wahrnehmung. Als Wissenschaftler und ehemaliger Universitätspräsident macht Hans Michael Piper deshalb die Innenwelt dieser Institution verständlich: Er erklärt, warum Studierende in ihrer Studienzeit eine entscheidende gesellschaftliche Prägung erfahren, warum Professor*innen egoistisch sein müssen oder warum hundert Gremien der Freiheit von Lehre und Forschung dienen - und was diese Freiheit gefährdet. Seine persönlichen Erfahrungen machen die Komplexität des deutschen Hochschulsystems sichtbar und verdeutlichen die Bedeutung der Universität als Bildungseinrichtung
    Note: German
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  • 15
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036596679 , 9783036596662
    Language: Undetermined
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Medicine ; Latinx ; family ; meaning ; communication ; coping with advanced cancer ; delirium ; liaison nurse ; misrecognition of delirium ; coordination ; breast cancer ; psychological distress ; quality of life ; women’s health ; qualitative study ; cancer care ; older adults ; mental health ; feeling safe ; home-dwelling ; patients with terminal cancer ; caregivers ; competency in anticipatory grief counseling ; emotional care ; person-centered care ; qualitative research ; anxiety ; depression ; family involvement ; hepatocellular carcinoma ; palliative care ; cancer ; decision-making ; nurse ; caregiving self-efficacy ; family caregiver ; oral cancer ; oncology ; nursing ; clinical nurse specialists ; cancer patients ; expanding nurses’ authority ; professionalization ; policy ; education
    Abstract: This collection of articles provides insight into the mental health and nursing care of individuals who are confronting a life-threatening illness. As individuals face a cancer diagnosis, there will be many challenges and changes in their lives. Emotional distress can emerge to greater and lesser degrees. Frequently, these individuals will require additional assistance to cope with the emotional distress they experience. Nurses have an important role in assessing this emotional distress and providing relevant interventions
    Note: English
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  • 16
    ISBN: 9783863098940
    Language: Undetermined
    Pages: 1 Online-Ressource (320 p.)
    Series Statement: Romanische Literaturen und Kulturen
    Keywords: History ; China ; Kulturbeziehungen ; Europa ; Geschichte 1600-1800
    Abstract: Os estudos reunidos nesta obra constituem um contributo importante para o alargamento do conhecimento das relações interculturais estabelecidas entre a Europa, nomeadamente Portugal, e a China, durante os séculos XVII e XVIII. Os treze textos revelam aspectos pouco conhecidos sobre arquivos e materiais e trazem à luz um conjunto de fundos documentais, boa parte deles inéditos. Em estreita articulação com os núcleos de documentação publicados na plataforma digital Res Sinicae, surgem abordadas obras e percursos colectivos e individuais de alguns agentes dessa interculturalidade, nomeadamente, alguns jesuítas portugueses da vice-província da China e da província do Japão: Álvaro Semedo (1585–1658), Francisco Furtado (1587–1653), António de Gouveia (1592/1594–1677), Francisco Cardim (1596–1659), Tomás Pereira (1646–1708) e Marcelo Leitão (1679–1755). O livro dá ainda a conhecer algumas das vias e meios da transmissão cultural e científica operada nos dois sentidos, entre a China e a Europa, no período 1600–1800. São tratados temas como a recepção de Martino Martini em Portugal, em 1657; o papel de jesuítas estrangeiros no ensino da matemática nos colégios jesuítas de Évora e de Lisboa, no século XVIII; a disseminação da astrologia europeia na Ásia; ou, ainda, de que forma a sinologia ocidental, já no século XIX, deixou de ser um campo de conhecimento dominado por missionários católicos. O livro «Res Sinicae». Pessoas, papéis e intercâmbios culturais entre a Europa e a China (1600–1800) reúne um conjunto de estudos inicialmente apresentados nas Jornadas «Res Sinicae 2021. Arquivos e Materiais», realizadas a 15 e 16 de Abril desse ano. Posteriormente, outros textos foram incorporados ao livro de modo a completar a temática em estudo. Os textos aqui publicados foram, numa primeira fase, objecto de avaliação do Conselho Editorial do projecto Res Sinicae e, numa segunda fase, alvo de peer review. A publicação desta obra, no quadro do projecto da Fundação para a Ciência e a Tecnologia (FCT) intitulado «Res Sinicae. Base digital de fontes documentais em latim e em português sobre a China (séculos XVI a XVIII). Levantamento, edição, tradução e estudos» (PTDC/LLT-OUT/31941/2017), albergado no Centro de Estudos Clássicos da Faculdade de Letras da Universidade de Lisboa, responde a uma das suas principais prioridades, a de produção e divulgação dos resultados científicos da investigação desenvolvida pela equipa e colaboradores. Os treze estudos reunidos neste volume revelam um conjunto de fundos documentais, boa parte deles inéditos, e apontam para novas vias de investigação no quadro das relações interculturais estabelecidas entre a Europa, com enfoque especial para Portugal, e a China, entre 1600 e 1800. Ficam, assim, abertas novas pistas de investigação, quer em relação a percursos individuais de intermediários culturais, quer em relação a estratégias colectivas de transferências de saberes e informação, quer em relação ao contacto e convívio com a alteridade. Tais caminhos foram possíveis a partir da revisitação de arquivos e fundos documentais conhecidos, assim como da revelação de novas colecções e da disponibilização de documentos inéditos fulcrais para o conhecimento dos intercâmbios registados nos dois sentidos, entre a China e a Europa na Idade Moderna
    Note: Portuguese
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  • 17
    ISBN: 9791221502664 , 9791221502657 , 9791221502671 , 9791221502688
    Language: Undetermined
    Pages: 1 Online-Ressource (145 p.)
    Series Statement: Knowledge and its Histories
    Keywords: Error ; Opinions ; Heresy ; History of Science ; History of Knowledge ; Philology ; Medicine ; Experiment ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDH Philosophical traditions and schools of thought
    Abstract: This volume offers a series of insights into the fascinating topic of errors and false opinions in early modern Europe. It explores the semantic richness of the category of ‘error’ in a time when such category becomes crucial to European thought and culture. During decades of increasing normativity in the social and religious sphere as well as in the epistemological status of disciplines, recognizing and correcting error becomes an imperative task whose importance can hardly be overestimated. The efforts at establishing religious, political, and scientific orthodoxy led philosophers, doctors, philologist, scientist, and theologians, to reconsider the very foundations of knowledge in the attempt to dispel errors. Spanning geographically from Italy to France, England, and Germany, the articles here gathered provide stimulating glimpses into one of the most fascinating, multifaceted, and controversial aspects of early modern culture
    Note: English
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  • 18
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036597942 , 9783036597959
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Medicine ; equine asthma ; exercise-induced pulmonary hemorrhage ; racehorse respiratory medicine ; donkey cardiology
    Abstract: Recent years have seen growing interest in equine lung and heart health, and advances in technology and a focus on equine welfare have driven this research. This Special Issue explores novel diagnostic and therapeutic approaches, including imaging techniques and lung function testing, immunological features, and immunomodulatory treatments for equine asthma and common racehorse respiratory issues. Moreover, it reports on novel echocardiography data of donkeys. This collection offers valuable insights into equine cardio-respiratory medicine
    Note: English
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  • 19
    ISBN: 9789942714657
    Language: Undetermined
    Pages: 1 Online-Ressource (93 p.)
    Keywords: Medicine ; Ansiedad ; estado ; rasgo ; Covid-19
    Abstract: This research analyzes the levels of trait-anxiety and state-anxiety, modifying a state-anxiety as an immediate emotional state, evolving over time. While trait-anxiety refers to relatively stable individual differences in anxiety. The objective was to determine levels of state-trait anxiety in times of Covid-19 pandemic in workers of Red de Salud Angaraes - Huancavelica, 2021. Methodology: basic research, descriptive level, synthetic analytical method, non-experimental, transactional, descriptive design, technique used, survey, Inventory of Trait-State Anxiety (IDARE), sample of 110 workers was used. Results: Concerning state anxiety levels, low level 7.27%, medium level 41.82% and high level 50.91%. Regarding trait anxiety, 6.36%, low level, 40.91% medium level and 52.73% high level. Regarding gender for state anxiety, for females, 2.73% low level, 20.00% medium level and 30.91% high level; for males, 4.55% low level, 21.82% medium level and 20.00% high level. According to gender, trait anxiety, females present 1.82% low level, 20.00% medium level and 31.82% high level. Males presented 4.55% low level, 20.91% medium level and 20.91% high level
    Abstract: Esta investigación analiza los niveles de ansiedad-rasgo y ansiedad-estado, modificando una ansiedad-estado como un estado emocional inmediato, evolucionando en el tiempo. Mientras que la ansiedad rasgo se refiere a diferencias individuales relativamente estables en la ansiedad. Tuvo como objetivo determinar niveles de ansiedad estado - rasgo en tiempos de pandemia Covid-19 en trabajadores de Red de Salud Angaraes - Huancavelica, 2021. Metodología: investigación básica, nivel descriptivo, método analítico sintético, diseño no experimental, transaccional, descriptivo, técnica utilizada, encuesta, se utilizó Inventario Ansiedad Rasgo Estado (IDARE), se tuvo muestra de 110 trabajadores. Resultados: Concerniente a niveles de ansiedad estado, se evidencia nivel bajo 7,27%, nivel medio 41,82% y 50,91% nivel alto. Respecto a ansiedad rasgo, 6.36%, nivel bajo, 40,91 % nivel medio y el 52,73% nivel alto. Respecto al género para ansiedad estado, para femeninos 2.73% nivel bajo, 20.00% nivel medio y 30.91% nivel alto; para masculinos, 4,55% nivel bajo, 21,82% nivel medio y 20,00% nivel alto. De acuerdo con el género, ansiedad rasgo, femeninos presentan 1,82% nivel bajo, 20.00% nivel medio y 31,82% nivel alto. Género masculino presentan 4,55% nivel bajo, nivel medio 20,91% y 20,91% nivel alto. Respecto a edad, trabajadores de 21 a 30 años presentan ansiedad estado en nivel bajo (2,7%), 22,7% nivel medio, y 9,1% nivel alto; de 31 a 40 años 2,7% nivel bajo, nivel medio 13,6%, y 34,5% nivel alto. Conclusión: Los trabajadores de la Red de Salud Angaraes, presentan nivel alto de ansiedad estado 50,91%, respecto a ansiedad rasgo, presentan un nivel alto 52,73%
    Note: Spanish
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  • 20
    Online Resource
    Online Resource
    Amsterdam : Amsterdam University Press
    ISBN: 9789463720496
    Language: Undetermined
    Pages: 1 Online-Ressource (342 p.)
    Series Statement: War, Conflict and Genocide Studies
    Parallel Title: Erscheint auch als Supreme courts under Nazi occupation
    Keywords: Second World War ; Courts & procedure ; Political structures: totalitarianism & dictatorship ; Europa ; Zweiter Weltkrieg ; Besetzte Gebiete ; Verfassungsgericht
    Abstract: This is the first extensive treatment of leading judicial institutions under Nazi rule in WWII. It focusses on all democratic countries under German occupation, and provides the details for answering questions like: how can law serve as an instrument of defence against an oppressive regime? Are the courts always the guardians of democracy and rule of law? What role was there for international law? How did the courts deal with dismissals, new appointees, new courts, forced German ordinances versus national law? How did judges justify their actions, help citizens, appease the enemy, protest against injustice? Experts from all democracies that were occupied by the Nazis paint vivid pictures of oppression, collaboration, and resistance. The results are interpreted in a socio-legal framework introducing the concept of 'moral hygiene' to explain the clash between normative and descriptive approaches in public opinion and scholarship concerning officials' behaviour in war-time
    Note: English
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  • 21
    Online Resource
    Online Resource
    Rennes : Presses universitaires de Rennes
    ISBN: 9782753592933 , 9782753587144
    Language: Undetermined
    Pages: 1 Online-Ressource (158 p.)
    Series Statement: Histoire
    Parallel Title: Erscheint auch als Transmettre l'Europe à la jeunesse
    Keywords: European history ; Schulbuch ; Europa ; Europäische Integration ; Europagedanke ; Vermittlung ; Jugend ; Geschichtsdenken ; Geschichtsbild ; Geschichtsbewusstsein
    Abstract: Dans le contexte de crise de l’Europe et d’interrogations sur son identité historique comme de son avenir, l’ouvrage présente une histoire culturelle des récits d’Europe transmis auprès des jeunes pour en faire des Européens depuis le xxe siècle. A-t-on assisté à l’édification de grands récits européens fédérateurs ou à une multitude de récits plus ou moins convergents, antagonistes, voire concurrentiels ? Dans cette fabrique narrative, quels faits historiques ont été choisis pour être transmis à la jeunesse européenne depuis le xxe siècle ? Sur quelles valeurs communes ces faits ont été évoqués ? Quels acteurs et quels vecteurs ont été engagés dans la construction de ces récits d’Europe ? En prenant des exemples dans différents pays européens tout en prêtant attention aux dynamiques transnationales, l’ouvrage rend compte de la variété des périodes ou figures historiques mobilisées dans ces narrations, de ses vecteurs de transmission (musées, festivals, rencontres sportives, manuels scolaires, littérature jeunesse, musées d’histoire, tourisme), comme de ses acteurs (eurodéputés, enseignants, associations d’éducation populaire, associations sportives, muséographes, et jeunes eux-mêmes)
    Note: French
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  • 22
    Online Resource
    Online Resource
    Montreal : McGill-Queen’s University Press (mqup)
    ISBN: 9780228017523 , 9780228017530 , 9780228017905 , 9780228018605
    Language: Undetermined
    Pages: 1 Online-Ressource (270 p.)
    Series Statement: Intoxicating Histories
    Parallel Title: Erscheint auch als Bhattacharya, Nandini Disparate remedies
    Keywords: 1870-1960 ; Pharmaindustrie ; Arzneimittelmarkt ; Pharmahandel ; Arzneimittel ; Traditionelle Medizin ; Kolonialismus ; Indien ; Medicine
    Abstract: At present India is a leading producer, distributor, and consumer of generic medicines globally. Disparate Remedies traces the genealogy of this development and examines the public cultures of medicine in the country between 1870 and 1960. The book begins by discussing the expansion of medical consumerism in late nineteenth-century India when British-owned firms extended their sales into remote towns. As a result, laboratory-produced drugs competed with traditional remedies through side-by-side production of Western and Indian drugs by pharmaceutical companies. The emergent middle classes, the creation of a public sphere, and nationalist politics transformed the medical culture of modern India and generated conflict between Western and Indigenous medical systems and their practitioners. Nandini Bhattacharya demonstrates that these disparate therapies were sustained through the tropes of purity or adulteration, potency or lack of it, and epistemic heritage, even when their material configuration often differed little. Uniquely engaging with the cultures of both consumption and production in the country, Disparate Remedies follows the evolution of medicine in colonial India as it confronted Indian modernity and changing public attitudes surrounding health and drugs
    Note: English
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  • 23
    ISBN: 9783036598437 , 9783036598444
    Language: Undetermined
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Medicine ; ulcerative colitis ; Crohn&rsquo ; s disease ; inflammatory bowel disease ; infliximab ; adalimumab ; certolizumab pegol ; golimumab ; vedolizumab ; ustekinumab ; therapeutic drug monitoring ; immunogenicity ; rheumatoid arthritis ; ankylosing spondylitis ; psoriasis ; clearance ; model informed precision dosing
    Abstract: Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn’s disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID
    Note: English
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  • 24
    Language: Undetermined
    Pages: 1 Online-Ressource (228 p.)
    Keywords: Medicine ; Evolución ; Culturas antiguas ; Revolución Industrial ; Sostenibilidad ; Nutrición
    Abstract: The book presents an in-depth exploration of the relationship between food and human evolution. It begins by deciphering the dietary changes of early hominids and how these changes influenced their physical and cognitive development, from dentition to increased brain size. It then analyzes the cultural and socio-political influence on diet in ancient civilizations such as Egypt, Rome and China. It highlights food in pre-Columbian cultures, highlighting agricultural diversity, sustainable practices and the cosmic connection with the earth. It also addresses the Industrial Revolution and how it transformed food patterns, leading to health problems in modernity. It also discusses the "green revolution" and technologies to improve food production. And finally, it explains sustainability in food systems and innovations for the future, such as laboratory meat and insect-based nutrition. The book concludes by recognizing nutrition as a multidisciplinary science, which seeks to ensure health and quality of life. This work is the result of a collective effort of academics seeking to understand human nutrition from its origins to the present
    Abstract: El libro presenta una exploración profunda de la relación entre la alimentación y la evolución humana. Inicia descifrando los cambios dietéticos de los primeros homínidos y cómo estos cambios influenciaron su desarrollo físico y cognitivo, desde la dentición hasta el aumento del tamaño cerebral. Luego analiza la influencia cultural y sociopolítica en la dieta de antiguas civilizaciones como Egipto, Roma y China. Se destaca la alimentación en culturas precolombinas, resaltando la diversidad agrícola, sus prácticas sostenibles y la conexión cósmica con la tierra. Aborda también, la Revolución Industrial y cómo transformó los patrones alimentarios, llevando a problemas de salud en la modernidad. También se discute la "revolución verde" y las tecnologías para mejorar la producción alimentaria. Y finalmente se explica sobre la sostenibilidad en los sistemas alimentarios y las innovaciones para el futuro, como la carne de laboratorio y la nutrición basada en insectos. El libro concluye reconociendo la nutrición como una ciencia multidisciplinaria, que busca garantizar la salud y calidad de vida. Esta obra es el resultado de un esfuerzo colectivo de académicos que buscan entender la alimentación humana desde sus orígenes hasta el presente
    Note: Spanish
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  • 25
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036598642 , 9783036598635
    Language: Undetermined
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Medicine ; inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a
    Abstract: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression
    Note: English
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  • 26
    ISBN: 9783839471456 , 9783837671452
    Language: Undetermined
    Pages: 1 Online-Ressource (294 p.)
    Series Statement: American Culture Studies
    Keywords: Cultural studies ; Political science & theory ; Medicine: general issues ; Biocultures ; Biosecurity ; Prevention ; Security ; Illness ; Self-surveillance ; America ; Biopolitics ; Medicine ; Cultural Studies
    Abstract: Discoveries in biomedicine and biotechnology, especially in diagnostics, have made prevention and (self)surveillance increasingly important in the context of health practices. Frederike Offizier offers a cultural critique of the intersection between health, security and identity, and explores how the focus on risk and security changes our understanding of health and transforms our relationship to our bodies. Analyzing a wide variety of texts, from life writing to fiction, she offers a critical intervention on how this shift in the medical gaze produces new paradigms of difference and new biomedically facilitated identities: biosecurity individuals
    Note: English
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  • 27
    Language: Undetermined
    Pages: 1 Online-Ressource
    Keywords: Medicine ; oncogenic drivers; signaling; pathways; hematologic malignancies; cancer ; thema EDItEUR::M Medicine and Nursing
    Abstract: oncogenic drivers; signaling; pathways; hematologic malignancies; cancer
    Note: English
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  • 28
    ISBN: 9781003271666 , 9781032222264 , 9781032222271
    Language: Undetermined
    Pages: 1 Online-Ressource (296 p.)
    Parallel Title: Erscheint auch als European planning history in the 20th century
    RVK:
    RVK:
    RVK:
    Keywords: Landscape art & architecture ; City & town planning - architectural aspects ; Urban & municipal planning ; Urban communities ; Aufsatzsammlung ; Europa ; Stadtplanung ; Geschichte 1900-2000
    Abstract: The history of Europe in the 20th century is closely tied to the history of urban planning. Social and economic progress but also the brute treatment of people and nature throughout Europe were possible due to the use of urban planning and the other levels of spatial planning. Thereby, planning has constituted itself in Europe as an international subject. Since its emergence, through intense exchange but also competition, despite country differences, planning has developed as a European field of practice and scientific discipline. Planning is here much more than the addition of individual histories; however, historiography has treated this history very selective regarding geography and content. This book searches for an understanding of the historiography of planning in a European dimension. Scholars from Eastern and Western, Southern and Northern Europe address the issues of the public led production of city and the social functions of urban planning in capitalist and state-socialist countries. The examined examples include Poland and USSR, Czech Republic and Slovakia, UK, Netherlands, Germany, France, Portugal and Spain, Italy, and Sweden. The book will be of interest to students and scholars for Urbanism, Urban/Town Planning, Spatial Planning, Spatial Politics, Urban Development, Urban Policies, Planning History and European History of the 20th Century
    Note: English
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  • 29
    Online Resource
    Online Resource
    Nijmegen : Radboud University Press
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Anthropology ; Health economics ; Health systems & services ; Health & personal development ; Medicine ; Public health & preventive medicine
    Abstract: In his professional journey, travelling through an upcoming field of surgery with apparently unlimited possibilities, Kees van Laarhoven witnessed major milestones and breakthroughs. Already as a medical student, he was amazed by surgical courage. During residency, he experienced hard work, diligence and perseverance of surgical professionals. Today as a surgeon with over 25 years of clinical experience he now looks at pieces of art in surgery with professionals compassionately bringing hope to patients.But he also sees inconvenient truths in our healthcare system, with patients evolving from one predictable and preventable disease to the next and with professionals following disease trends rather than applying their knowledge to redirect disease into health. The modern disease-oriented care system becomes undesirable and unsustainable. And there are more inconvenient truths that have progressed rather than diminished in time. Healthcare is not easily accessible to the major half of the global population and for those who have access, with a growing global population, healthcare may become unaffordable in the future. Moreover, from an environmental perspective, both human and planetary health are compromised and ask for a ‘One Health’ approach. Being fascinated by the questions of how and why did this all happen, Kees van Laarhoven took up a scientific survey to comprehend and learn how things still can be changed. He found that clear solutions are there! Please join him on his journey
    Note: English
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  • 30
    Language: Undetermined
    Pages: 1 Online-Ressource
    Keywords: Medicine
    Abstract: The war in Syria has lasted for many years and continues to cast a dark shadow over its people, including healthcare workers caring for those injured and in distress. During the war, healthcare workers have been exposed to unprecedented challenges, becoming targets of bombing, killing, siege, arrest, and torture. Moreover, healthcare workers continue to experience difficult situations that require them to make decisions with no clear or easy moral choice. The present study aimed to understand the experiences of healthcare workers and the difficulties and challenges that hinder applying existing ethical frameworks and codes for disasters within Syria’s context of revolution and war. Qualitative analysis of interviews led to classification of the ethical challenges experienced by healthcare workers into four groups: the risks from providing care; stewardship of resources and work challenges; corruption and organizational pressure; and psychological, emotional, and social stress. The study also showed that both Syrian healthcare workers and the developers of ethical frameworks adopt many similar values and principles. Yet, the participants adopted several unique moral values not identified in ethical frameworks as a result of navigating their professional duties under the circumstances of the Syrian war. At last, recognizing the challenges and precarious tasks healthcare workers cope with during wars and other similar disasters could help volunteers, medical personnel, and humanitarian organizations deciding to work in Syria better understand the specific context and obstacles for ethical decision-making. Moreover, attracting attention for and support of Syrian healthcare workers locally and globally presents a long-lasting benefit
    Note: English
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  • 31
    ISBN: 9783732909643 , 9783732989775
    Language: Undetermined
    Pages: 1 Online-Ressource (521 p.)
    Series Statement: Transkulturalität – Translation – Transfer
    Keywords: Translation & interpretation ; France ; Germany ; USA ; Mexico
    Abstract: Translation does not work in a vacuum. Making it visible as action in a structured context is the goal of this book. This broad context includes individuals and, more significantly, collective actors-publishers, reviewers and patrons, publishers, journals, social and political organizations. Individually and collectively, they form dynamic, interactive, and interdependent networks. These are essential for translation in exile, as they influence the production and reception of translations both positively and negatively. If they are missing, not only working conditions change, but entire biographies. Newly emerging networks, on the other hand, create the conditions for translating. What are the working and living conditions, the structures of action and publication in which translations are produced? What roles do they play in the lives and aesthetic careers of individual translators in exile? Answers can be found in this book
    Note: German
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  • 32
    ISBN: 9783036592442 , 9783036592459
    Language: Undetermined
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Medicine
    Abstract: The growing improvement of medical sciences in the diagnosis and treatment of head and neck oncological diseases has produced a significant increase in the life expectancy of affected patients. it is therefore necessary to direct new energies towards understanding and protecting the quality of life of cancer patients. This reprint presents the fruit of the research protocols of numerous groups around the world on the topics of life expectancy and quality of life of patients suffering from head and neck cancer
    Note: English
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  • 33
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587974 , 9783036587967
    Language: Undetermined
    Pages: 1 Online-Ressource (330 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Research in ophthalmic drug delivery has developed significant advances in the last few years, and efforts have been made to develop more effective topical formulations to increase drug bioavailability, efficiency, and safety. Drug delivery to the posterior segment of the eye remains a great challenge in the pharmaceutical industry due to the complexity and particularity of the eye's anatomy and physiology. Some advances have been made with the purpose of maintaining constant drug levels in the site of action. The anatomical ocular barriers have a great impact on drug pharmacokinetics and, subsequently, on the pharmacological effect.Despite the increasing interest in efficiently reaching the posterior segment of the eye with reduced adverse effects, there is still a need to expand the knowledge of ocular pharmacokinetics that allow the development of safer and more innovative drug delivery systems. These novel approaches may greatly improve the lives of patients with ocular pathologies
    Note: English
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  • 34
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587790 , 9783036587783
    Language: Undetermined
    Pages: 1 Online-Ressource (182 p.)
    Keywords: Medicine
    Abstract: This Special Issue dives into the evolving realm of sports science by exploring innovative methods to enhance athletes' motor skills and performance. It showcases research studies aiming to discover validated strategies, cutting-edge approaches, and the intricate interplay of factors that shape athletic excellence. From training methodologies to technological advancements, this collection of empirical investigations and reviews offers valuable insights for both trainers and scientists. We invite readers to join us in uncovering the science behind peak athletic achievement
    Note: English
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  • 35
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589657 , 9783036589640
    Language: Undetermined
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Medicine
    Abstract: Chronic obstructive pulmonary disease (COPD) is a disorder characterized by airflow limitation and is one of the major causes of mortality and morbidity across the globe. Although several guidelines have been published over the past three decades, they were generated in response to the fact that COPD is a major cause of mortality and morbidity and remains an important social problem. In the 20th century, forced expiratory volume in one second (FEV1) was the single most important measure in patients with COPD from discriminative, evaluative, and predictive standpoints. We found that dyspnea is a better mortality predictor than FEV1 in 2002 and exercise capacity in 2003. Subsequently, it has become apparent that physical activity is more predictive of mortality. Furthermore, we have recently developed the tendency to use the reduction of the future risk of exacerbation as the endpoint of relatively large-scale clinical trials rather than the improvement of FEV1. Many researchers have continued to seek better outcome markers and have also discussed what should be used as primary or secondary endpoints in clinical trials in subjects with COPD. We have undoubtedly made great progress but still have a lot of work to do for the best interests of patients
    Note: English
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  • 36
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591766 , 9783036591773
    Language: Undetermined
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: The field of orthopedic trauma has always been a discipline cahacterized by rapid innovation and creative evolution. We see evolution in every facet of orthopedic surgery, ranging from the transformation of the understanding of implant design and biomechanics to the understanding and monitoring of fracture healing and the management of complications. This Reprint includes many articles discussing topics, such as distal radius fractures, hip fractures, osteoarthritis, ankle fractures, acetabular fractures, and anterior cruciate ligament reconstruction
    Note: English
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  • 37
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587998 , 9783036587981
    Language: Undetermined
    Pages: 1 Online-Ressource (316 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Research in ophthalmic drug delivery has developed significant advances in the few last years, and efforts have been made to develop more effective topical formulations to increase drug bioavailability, efficiency, and safety. Drug delivery to the posterior segment of the eye remains a great challenge in the pharmaceutical industry due to the complexity and particularity of the eye's anatomy and physiology. Some advances have been made with the purpose of maintaining constant drug levels in the site of action. The anatomical ocular barriers have a great impact on drug pharmacokinetics and, subsequently, on the pharmacological effect.Despite the increasing interest in efficiently reaching the posterior segment of the eye with reduced adverse effects, there is still a need to expand the knowledge of ocular pharmacokinetics that allow the development of safer and more innovative drug delivery systems. These novel approaches may greatly improve the lives of patients with ocular pathologies
    Note: English
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  • 38
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589022 , 9783036589039
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Aortic aneurysm is a multifactorial progressive life-threatening disease. Recent surgical treatment and endovascular repair help to prevent aortic ruptures. However, there are no effective pharmacological treatments to limit aneurysm growth. This Special issue, entitled “Aortic Aneurysms: Vascular Remodeling and Repair", represents a collection of articles from innovative scientists that focuses on the recent advances in diagnostics, pathogenesis and therapies of aneurysms. This reprint includes a systematic review and nine original papers on clinical imaging, prognostic methods, genome-wide screening, novel cell signaling pathways and drug targets. We hope that readers will gain a deeper understanding of this topic and enjoy reading this reprint
    Note: English
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  • 39
    ISBN: 9781685710989
    Language: Undetermined
    Pages: 1 Online-Ressource (191 p.)
    Keywords: Literary studies: from c 1900 - ; USA ; Political structures: democracy
    Abstract: With the 2020 election, political polarization in the U.S. entered a ludicrous end-stage. Partisanship, once a pseudo-rational system of biases, has devolved to a conflict between incompatible realities. In search of some pathway toward consensus, Evil Twins and the Ultimate Insight: Ayn Rand, Vladimir Nabokov, and the Polarized Politics of Reading looks to the works of two iconic Russian-American writers whose literary rivalry mirrors the rift between political parties in the U.S. The matchup has all the markings of an evil-twin narrative, pitting Rand, the muse of libertarian conservatism, against Nabokov, the trickster-genius of the Western canon. Their mid-century novels afford a rare opportunity to arbitrate, by proxy, American political grievances and resolve, in print, its electoral dysfunction. Evil Twins and the Ultimate Insight mounts this critical intervention into the Blue/Red blood feud and contemplates, in the cognitive challenges of Nabokov’s fiction, a remedy for its polarized politics. To guard against grandstanding, axe-grinding, deck-stacking, inaccuracy, or obfuscation, Stone’s book proceeds by indirection, exploring four scholarly books that all speak to the peculiar relationship between Rand and Nabokov: Gene Bell-Villada’s On Nabokov, Ayn Rand and the Libertarian Mind (2013), Adam Weiner’s How Bad Writing Destroyed the World: Ayn Rand and the Literary Origins of the Financial Crisis (2016), Michael Rodgers’s Nabokov and Nietzsche: Problems and Perspectives (2018), and Peter Roberts and Herner Saeverot’s Education and the Limits of Reason: Reading Dostoevsky, Tolstoy and Nabokov (2018). Each of these books is seriously flawed, but their numerous interlocking problems conspire to reveal, empirically, via negativa, how literature might tip the scales in America’s partisan deadlock. Ultimately, Stone argues that, when our books get tangled up in our politics, their promise—to help us see to the bottom of things and scooch closer to the asymptote of truth and reality—might be something more than a mirage
    Note: English
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  • 40
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589565 , 9783036589572
    Language: Undetermined
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Medicine
    Abstract: The primary aim of this reprint is to describe the genomics of splenic lymphomas, hairy cell leukemia, Cutaneous lymphomas, plasma cell leukemia, MDS with deletion 5q, mastocytosis, hypodiploid acute lymphoblastic leukemia, CLL with complex karyotype and other rare hematologic cancers
    Note: English
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  • 41
    ISBN: 9783036590783 , 9783036590790
    Language: Undetermined
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: Today, interventional treatment and clinical management of cardiac arrhythmias represent a continuous challenge. This is mainly due to the widening of indications for implantable electronic devices and for catheter ablation procedures as well as the continuous improvement of technologies and medical therapies. Despite international guidelines and worldwide consensus updates, evidence gaps persist at all points in the real-world setting. This Special Issue aims to provide a comprehensive overview of advances in the indications, diagnosis, and treatment of cardiac rhythm disturbances, with particular interest in the use of innovative techniques and technologies in interventional therapies
    Note: English
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  • 42
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591612 , 9783036591605
    Language: Undetermined
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Medicine
    Abstract: This collection brings together basic and clinical research papers that cover different topics in audiology but have one thing in common: the translational approach. The research in this collection demonstrates how exciting and interesting translational audiology can be. This collection aims to stimulate interest and encourage more studies of this type
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  • 43
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593661 , 9783036593678
    Language: Undetermined
    Pages: 1 Online-Ressource (462 p.)
    Keywords: Medicine
    Abstract: There are a variety of anesthetic management options during surgery, and these are constantly evolving. Both innovative and confirmatory research are important if the scientific community aims to develop and improve people’s quality of care. This reprint introduces new avenues and covers questions regarding innovative anesthetic techniques and unmet needs after surgery, paving the way for future improvements. It can be useful for both clinicians and clinical researchers, especially in light of the expansion of concepts like personalized care
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  • 44
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577708 , 9783036577715
    Language: Undetermined
    Pages: 1 Online-Ressource (152 p.)
    Keywords: Medicine
    Abstract: Studies on global human genomic variation have shown important population-based differences in allele frequencies of common single-nucleotide polymorphisms (SNPs) that influence the expression of genes related to nutrition and, secondarily, chronic disease. Some SNP sites have known functions or associations with diseases or other phenotype characteristics, including nutritional deficiencies and metabolism dietary components. There are many components of human diets that, when combined with the impact of diverse genetics on the metabolism of certain nutrients, have the capacity to give rise to harmful diet–gene interactions. This situation has the potential capacity to modify molecular phenotypes and clinical phenotypes, including human disease. Obesity, diabetes mellitus, chronobiology, osteoporosis, cancer, and many other diseases are fields of potential investigation in this topic area. This Special Issue will include manuscripts that focus on the complex relationship between gene polymorphisms and nutrition across all physiological and chronic diseases
    Note: English
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  • 45
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589404 , 9783036589411
    Language: Undetermined
    Pages: 1 Online-Ressource (268 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Gastroenterology and hepatology are fields of research that have improved considerably in recent years in terms of clinical approach, diagnosis, and therapy. However, there is still much to be clarified and explored, and many questions remain unanswered. Therefore, basic research, including translational and clinical discoveries, supported by technological innovations such as artificial intelligence, will enable further steps toward better, more refined treatments for many digestive diseases. The challenge of modern medicine will therefore be to connect these two fields to ensure optimal patient management. Further innovations will help clinicians to improve clinical practice, establish new guidelines, and provide personalized treatment based on patient characteristics. The aim of this Special Issue is to highlight recent advances and future challenges in gastroenterology and hepatology
    Note: English
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  • 46
    ISBN: 9783036592763 , 9783036592770
    Language: Undetermined
    Pages: 1 Online-Ressource (246 p.)
    Keywords: Medicine
    Abstract: Chronic immune-mediated inflammatory diseases (IMIDs), usually accompanied by cardiovascular disease and neoplasias, are now prevailed worldwide. The limited efficacy of current therapeutics and a proportion of non-responders are linked to missing aspects in their pathophysiology at the molecular and cellular levels. High-throughput single- and multi-omics approaches and their combinations are expected to pinpoint the key players underlying IMIDs’ establishment and/or progression, thus suggesting potential therapeutic targets and biomarkers. This Reprint gathered 13 papers presenting recent relevant data related to the assessment of CVD risk in RA, tailored therapeutics in RA-interstitial lung disease, IgG4-related RA, and Sjögren’s syndrome, enabling early identification of PsA and improving outcomes in patients’ with psoriasis. Also, novel non-invasive biomarkers for endoscopic activity and mucosal healing in ulcerative colitis, IBD, and cell-death-associated inflammatory syndromes are proposed. Moreover, a certain subset of telocytes is suggested as the pilot governor of epithelial behavior in preneoplastic gastric lesions, a newer member of IL-1 family, as it is a critical partner in lung adenocarcinoma, while distinct transcriptomic signatures and pathway profiles in human melanocytes corresponding to different Staphylococcal superantigenic enterotoxins are possible targets for therapeutic intervention in cases of toxic shocks. Lastly, Tregs- and dendritic cell-based IMID biomarkers are recommended to enable at more efficient, personalized, and precise treatment strategies
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  • 47
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591100 , 9783036591117
    Language: Undetermined
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Medicine
    Abstract: Vestibular medicine relates to the assessment, diagnosis, and treatment of patients with dizziness and vertigo. In all these fields, there has been an enormous increase in research during recent years. This edition includes a discussion on the epidemiology of dizziness, the role of genetics in the development of vestibulopathy, diagnostic approaches, and interventions for patients with dizziness and vertigo: medical treatment, surgery, and vestibular rehabilitation
    Note: English
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  • 48
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591940 , 9783036591957
    Language: Undetermined
    Pages: 1 Online-Ressource (394 p.)
    Keywords: Medicine
    Abstract: Nurses represent the highest number of healthcare workers globally and have played a critical role in the COVID-19 pandemic. This reprint highlights the issues and challenges faced by nurses practicing in hospital and community settings during the COVID-19 pandemic. The manuscripts herein focus on nurses in various areas of practice, including nurse managers, highlighting the impact, experience, and reality of providing care during the crisis. Interventions and strategies to support practice environments and the mental health and wellbeing of the nursing workforce were identified. Evidence from these manuscripts shed light on how nurse leaders can provide relevant, coordinated, and consistent organizational and leadership support to better establish a safe and healthy work environment that protects and fosters the mental health and wellbeing of all nursing personnel. The pandemic exacerbated the already demanding quality of work environments for nurses, as well as their mental health and wellbeing, thereby inducing a global nursing shortage; therefore, improving these factors, which ultimately influence nurse retention, is critical. We trust that sharing the lived experiences of nurses during the COVID-19 pandemic can enable us to leverage their expertise in meeting the complex care needs of patients, including COVID-19 patients, while improving the care needed by nurses in their working environments, alongside preparing for future pandemic waves
    Note: English
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591667 , 9783036591674
    Language: Undetermined
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Bioactive metabolites from marine-derived fungi are known to be an important source of drug discoveries. Natural product scientists have explored various environments, such as the deep ocean and polar regions, as well as marine mangrove ecosystems, to discover unique fungi strains which could produce new bioactive structures. The aim of this Special Issue is to highlight the diversity of fungi derived from different marine environments, as well as their potential as producers of bioactive marine natural products. Innovative scientific results, as well as approaches and methodologies applied in marine natural product discovery areas, are encouraged. Studies on the biosynthesis and bioactivities of marine natural products are also welcome. For this Special Issue, we invited academic and industry scientists to submit reviews and original and conceptual research articles highlighting diversified marine fungi as a source of bioactive natural products
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  • 50
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    Prague : Karolinum Press
    ISBN: 9788024651965 , 9788024656922
    Language: Undetermined
    Pages: 1 Online-Ressource (83 p.)
    Keywords: Medicine
    Abstract: Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592480 , 9783036592497
    Language: Undetermined
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Medicine
    Abstract: As Guest Editors, we are very delighted to see the reprint of our Special Issue, “Head and Neck Surgery: Clinical Updates and Perspectives", which is published in the Otolaryngology section of the Journal of Clinical Medicine. These papers are the joint effort of many excellent colleagues who have devoted their lives and careers to the exciting field of Otorhinolaryngology. As both clinicians and surgeons, we are actively advancing the diagnosis and management of the myriad of conditions affecting the head and neck region. Unprecedented discoveries in the field of genetics and molecular biology are always integrated with sound knowledge of the intricate anatomy of our discipline, while technological advancements now permit us to provide tailored and minimally invasive treatments for our patients. We wish to thank all the authors who contributed to this publication and we hope you enjoy reading it
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590868 , 9783036590875
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: The Special Issue “Bioactive Secondary Metabolites of Marine Fungi” gathered ten publications, including two reviews and eight research articles, about marine fungi, ranging from the isolation and structure elucidation of new natural products to the biosynthetic pathways of marine fungal metabolites
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  • 53
    ISBN: 9783036567747 , 9783036567754
    Language: Undetermined
    Pages: 1 Online-Ressource (258 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: This reprint focuses on ecosystem observation, simulation and assessment. Ecosystems provide supply, regulation, culture and support services for human beings in addition to overall support human survival and sustainable development. However, driven by multiple factors such as climate change, population growth, urbanization, and exploitation of mineral resources, global problems such as ecosystem degradation and biodiversity loss have affected the sustainable development of human beings. Because of this, it has become a hot spot in ecology research to develop basic theories, model methods and technical means for ecosystem observation, simulation and evaluation for the quantitative analysis of the structure, process and function of ecosystems as well as the improvement of the scientific understanding of the changing characteristics and evolution laws of natural ecosystems
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  • 54
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565545 , 9783036565552
    Language: Undetermined
    Pages: 1 Online-Ressource (322 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Robotics and intelligent systems are key technologies to promote efficient and innovative applications in the most diverse domains (industry, healthcare, agriculture, construction, mobility, etc.), performing and supporting activities that are not suitable to be performed by humans. Such activities are frequently time-consuming, repetitive tasks with low added value, which are physically demanding and/or dangerous. Nevertheless, robotics and intelligent systems face several scientific and technological challenges related to their integration and interoperability with other systems, safety, flexibility, re-configurability and autonomy. These challenges are especially relevant when robots operate in real unstructured environments and share a workspace with humans and other equipment. This reprint collects research achievements, ideas, and applications regarding advanced intelligent robotic systems, covering diverse technologies and application domains. Generically, the contributions cover optimal path-planning strategies and innovative designs for mobile manipulators, the integration of robotic and intelligent systems, grasping, manipulation, teleoperation, haptics, user experience approaches for collaborative robots, and multi-agent systems
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  • 55
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567013 , 9783036567006
    Language: Undetermined
    Pages: 1 Online-Ressource (420 p.)
    Keywords: Medicine ; Epidemiology & medical statistics
    Abstract: Constant striving to reduce pollutant emissions, greenhouse gases and energy consumption, i.e., sustainable development, forces the development of new and improved materials, technologies and manufacturing processes. One of the areas of sustainable development of the global economy is also the development of laser devices and the spreading of laser technology applications.The book deals with important issues related to the development of science and technology in the field of application the laser beam for joining, surface treatment, coatings. However, the thematic scope is not limited only to mentioned issues. The scope of the book covers issues related to advances in computational modelling of heat sources in laser and arc processes, unique techniques of underwater welding or unique techniques of forced cooling the weld metal under solidification during arc welding or hybrid process of laser deposition under cryogenic conditions, microstructural and mechanical characterisation of coatings and joints produced by different welding technologies. The above book contains valuable information, both theoretical and practical research results in the field of advanced technologies of joining, surface treatment and coatings, quality control and assessment, as well as management of the technological processes. Therefore, I deeply believe that the book will be a valuable and helpful for young scientists, engineers, and students in the field of welding and surface engineering, materials science, and manufacturing engineering
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  • 56
    ISBN: 9783036568706 , 9783036568713
    Language: Undetermined
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Medicine ; Oncology
    Abstract: This reprint focuses on artisanal and small-scale gold mining (ASGM) all over the world, as well as its impact on the economy, environment, and health, providing sustainable solutions to severe ASGM problems. This book presents a total of 20 published articles of regions including Southeast Asia, South America, and South Africa, as well as a general overview of ASGM issues. Studies included in this book posit that (1) ASGM activity is still widely practiced as an alternative livelihood in rural areas in many countries around the world, using toxic elements such as Hg and cyanide due to a lack of legal enforcement on the ASGM sector; (2) ASGM has a negative impact on environmental ecosystems, causes occupational health problems for miners, and causes chronic health disorders in both ASGM communities and those living far from ASGM areas. However, some studies propose that specific potential bioindicators could be used to monitor the environment and health of those living in ASGM communities, providing sustainable solutions to severe ASGM problems
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  • 57
    ISBN: 9783036559810 , 9783036559827
    Language: Undetermined
    Pages: 1 Online-Ressource (372 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: This reprint focuses on the application of ventilation and indoor air quality (IAQ) in different settings, and is centred around different indoor environments and policymaking issues. It also explores how issues around health, IAQ and ventilation have evolved through the COVID-19 crisis. In connection with the growing need to determine and assess IAQ, new research seeks to test and investigate new methodologies based on research topics which include an increasing number of harmful substances and test methods. Ventilation and Indoor Air Quality ultimately aims to provide the reader with a comprehensive range of case studies, seeking to solve ventilation and IAQ issues from different perspectives. It presents 19 chapters related to regulations, homes, modelling, field studies, and technology related to ventilation and IAQ. Overall, this reprint provides state-of-the-art analysis and reviews so that readers with any level of prior knowledge of ventilation and IAQ are introduced to the latest research on these issues. This reprint was written to inspire and stimulate the development of further multidisciplinary research on IAQ issues
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566030 , 9783036566023
    Language: Undetermined
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Medicine
    Abstract: Environmental quality is crucial to our health, economy, lives, and for future generations. However, during the last few years, we have faced several serious challenges, which include, but are not limited to, climate change, unsustainable consumption and production, as well as various forms of pollution. These challenges are of global concerns for the sustainable development of human beings. This reprint has collected review and research papers aimed at a wide range of environmental topics: water and wastewater treatment and management, soil degradation and conservation, pollution control, the environmental impact of technologies, air quality and the indoor environment, and advanced environmental materials. Analytical methods developed for the determination of environmental pollutants were also welcomed. Papers dealing in the synthesis of adsorbents for the solid-phase extraction of environmental pollutants also fell within the scope of this Special Issue. Contributions describing novel and significant knowledge, scientific results, and advanced applications in the field of environmental sciences and technology were also welcomed. This reprint provides an integrated view of the trends in solving the problems associated with the achievement of sustainability in environmental technology
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  • 59
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565293 , 9783036565309
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Keywords: Medicine
    Abstract: Non-destructive testing and evaluation are commonly referred to as the vast group of analysis techniques used in civil, medical, and industrial sectors to evaluate the properties of materials, tissues, components, or structures, without causing any damage. Automation offers many benefits for non-destructive testing to cope with increasing demands, including improved reliability and higher inspection speeds. Additionally, robots enable inspections in locations that are not easily accessible to human operators and allow for humans to be removed from potentially dangerous environments. However, the perceived complexity and high costs have limited the adoption of automation. As a result, the full potential that could be derived from the seamless integration of robotic platforms with sensors, actuators, and software has not been fully explored; it could still revolutionise the way that automated inspections are performed and conceived. The recent advancements in electronics, robotics, sensor technology and software pave the way for new developments in automated testing and data-driven autonomous robotic inspections in several sectors. This Special Issue aimed to attract the latest research outcomes in the field of robotic sensing. Five papers relate to inspection systems based on robotic fixed-base manipulators, three of which are associated with in-process inspection in manufacturing applications (robotic wire-arc welding and additive manufacturing). Four papers report research advancements in mobile robotic-enabled sensing
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  • 60
    ISBN: 9783036566610 , 9783036566603
    Language: Undetermined
    Pages: 1 Online-Ressource (220 p.)
    Keywords: Medicine
    Abstract: Authenticity and traceability are crucial in order to overcome frauds in the international food trade. Control measures are perceived as the greatest vulnerability in the food supply chain. In order to decrease contribution to the overall perceived fraud vulnerability, analytical approaches and chemometrics are usually employed
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  • 61
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566979 , 9783036566962
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Keywords: Medicine ; Oncology
    Abstract: Arthropod disease vectors transmit not only serious diseases, such as malaria, but many other diseases as well, many of which are neglected to various extents. In most cases, a tripartite interaction is involved between the arthropod disease vector, the vertebrate host, and the vector-borne pathogens. The reprint aims to present a selection of the latest data (and up to date information in the case of reviews) about the molecular and biochemical events that mediate this tripartite interaction with emphasis on ticks and mosquitoes
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567488 , 9783036567495
    Language: Undetermined
    Pages: 1 Online-Ressource (160 p.)
    Keywords: Medicine ; Mental health services
    Abstract: Dry pasta is one of the most popular staple foods worldwide due to its convenience in terms of affordability, versatility, long shelf life, as well as sensory and nutritional value. As such, it represents a suitable carrier for health-promoting substances providing specific physiological functions. This Special Issue deals with the continuum aspects, “from seed to fork”, that could have an impact on the nutritional, sensory, and technological aspects of pasta. In this Special Issue, we aimed to publish innovative research and review papers on physico-chemical and sensorial characteristics, nutritional value, functional and technological properties of pasta, and pasta-making processes. New raw materials, new functional ingredients, up-cycling of waste materials, in vivo experiments to test the effect of assumption of the supplemented pasta, and innovative packaging systems will also be addressed in this Special Issue. Predictions of pasta quality adopting chemometrics as well as multi-variate and statistical data analysis approaches were welcomed. Finally, in the medium term, the international pasta market is expected to stay negative unless tangible product innovations are introduced, particularly regarding the technological innovations aimed at improving the products’ health benefits. This Special Issue aimed to provide a fundamental understanding and present the current strategies to improve the technological, nutritional, and sensory properties of pasta
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    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568058 , 9783036568041
    Language: Undetermined
    Pages: 1 Online-Ressource (256 p.)
    Keywords: Medicine ; Oncology
    Abstract: Energy systems have played an essential role in the history of human civilization. As our civilization evolves, energy systems are expected to adapt to the environment and desire of people for more sustainable development whilst meeting the ever-increasing energy demand of society. To address global warming and its threats to sustainable development to multiple ends, major economies around the world have announced low-carbon, carbon-neutral, or negative-carbon development targets. To meet these goals, the energy systems as we know them today need to undergo substantial structural changes in terms of the way primary energy is extracted from nature, converted to secondary energy, transmitted from conversion sites to end use, and shifted between time slots to coordinate supply and demand. The share of renewable and fossil energy in the overall energy portfolio could experience unprecedented structural change of a kind not witnessed since industrialization. To cope with this harsh transition, energy systems should be planned, designed, retrofitted, and operated in a revolutionary manner.This reprint aims to present the most recent advances in energy systems analysis towards low/zero/negative carbon emission targets via integration amongst different primary energy supplies, between multiple energy supplies and demands, across geographically separated regions, and over different time scales from seconds to seasons
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    ISBN: 9783036564852 , 9783036564869
    Language: Undetermined
    Pages: 1 Online-Ressource (182 p.)
    Keywords: Medicine
    Abstract: The present reprint contains all of the articles accepted and published in the Special Issue "Probability and Stochastic Processes with Applications to Communications, Systems and Networks" from the MDPI Mathematics journal. This Special Issue is devoted to probability, statistics, stochastic processes and their different applications in system and network analysis. The Special Issue includes works related to the analysis and applications of different queuing models, which begin with general approaches in modeling queuing systems and networks; an analysis of probabilistic and statistical methods in telecommunication; an asymptotic analysis of queuing networks in the condition of a large load; general complex networks and their structures, e.g., topology and graph theory; mathematical methods and models in smart cities; exclusive statistical methods, such as statistical estimates in bio/ecology, medicine and neural networks; and studies that estimate parameters in complex technical systems, etc. We hope that the scientific results collected in this reprint will help foster future research related to probability, stochastic processes and their applications
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  • 65
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567709 , 9783036567716
    Language: Undetermined
    Pages: 1 Online-Ressource (238 p.)
    Keywords: Medicine
    Abstract: This reprint is excellent proof that, despite more than a hundred years of research into hydrogen bonds, they are still an interesting and fundamental topic in the natural sciences. The collected articles deal with various aspects of the existence of hydrogen bonds and show human ingenuity in the field of inventing and applying various techniques, both experimental and theoretical, in order to describe them more fully
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  • 66
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567143 , 9783036567150
    Language: Undetermined
    Pages: 1 Online-Ressource (252 p.)
    Keywords: Medicine ; Oncology
    Abstract: This reprint aims to disseminate the latest research achievements, findings, and ideas in the robotics field, with particular focus on the Italian scenario. It covers a range of topics related to the theory, design, practice, and applications of robots, such as robot design and kinematics, dynamics of robots and multi-body systems, linkages and manipulators, control of robotic systems, trajectory planning and optimization, innovative robots and applications, industrial robotics, collaborative robotics, medical robotics, assistive robotics, and service robotics. The reprints contributions include (but are not limited to) revised and substantially extended versions of selected papers that were presented at the 2nd International Conference of IFToMM, Italy (IFIT 2018)
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567679 , 9783036567662
    Language: Undetermined
    Pages: 1 Online-Ressource (218 p.)
    Keywords: Medicine ; Neurology & clinical neurophysiology
    Abstract: The Special Issue “Radioactive Pollution and Biological Effects of Radioactivity“of the Journal Life involved the participation of academic scientists, researchers, and scholars from all over the World that contributed with articles, reviews, and case reports, based on high-quality research works.The common topic of the published works concerns the radioactive pollution, which occurs when radioactive elements enter the atmosphere and reach the Earth’s surface, within solids, liquids, or gases, including the human body. This happens after natural and/or man-made activities, such as nuclear tests, industrial waste (e.g., radiodiagnostics), and excesses of naturally occurring radioactive sources. This kind of pollution entails risks of radiological contamination of the environment, with harmful effects on human health caused by the ionizing radiation. This theme has become even more current due to the increasing use of ionizing radiation for domestic, industrial, and medical purposes during the last century. Radiological monitoring is a primary objective of radiation protection in order to estimate and understand the impact of radionuclides on the environment and to assess the health risk for the population.The aim of the Special Issue has been to provide an interdisciplinary platform for researchers to exchange and share their experiences and latest achievements on all aspects of radioactive pollution. Survey data analysis, original and unpublished results of conceptual, constructive, empirical, experimental, and theoretical work were welcome, as well as other concepts related to the radiation field
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  • 68
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567938 , 9783036567921
    Language: Undetermined
    Pages: 1 Online-Ressource (426 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: In recent years, there has been a growing need for both nutritional and healthy foods with superior functional properties. In this line, bioactive compounds are economically available in different foods systems with limitations in quality and functionality.The present Special Issue is placed in this context, and aimed to provide a collection of modern chemical strategies developed with the intent of extracting, characterizing, tracing, or authenticating food bioactive compounds. Original research articles dealing with innovative techniques for the extraction (e.g., green chemistry) of bioactive compounds were welcomed. In addition, when discussing modern analytical methods, the structural characterization and identification of these active components were required. Attention was also devoted to theoretical aspects of the determination of the bioactivity and mechanisms of action of food bioactive compounds, as well as challenging properties for application as drug agents. Review articles providing an overview of the latest trends in this area of interest were also very welcomed
    Note: English
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  • 69
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563480 , 9783036563497
    Language: Undetermined
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Medicine ; Neurosciences
    Abstract: Many heterogeneous causes (e.g., metabolic, inflammatory, autoimmune, vascular, and renal diseases, and even drugs), collectively grouped as secondary causes of osteoporosis, may lead to bone loss or damage to architecture through a number of mechanisms. Although these secondary causes of osteoporosis are the most frequently observed causes of unexpected bone loss, they can only be diagnosed via a high degree of suspicion and clinical experience and by performing the appropriate investigations. In inflammatory disorders such as rheumatoid arthritis or chronic inflammatory bowel diseases, as well as vascular diseases, T-cell activation, and consequently pro-inflammatory cascades, trigger the increased expression of T-cell-derived RANKL. In addition, a new biomarker signature of bone-related miRNAs is promising in certain clinical features. Glucocorticoids, often used to control disease activity, decrease the number and function of osteoblasts and inhibit OPG expression. The ubiquitous occurrence of disease-related secondary changes in bone metabolism implies that numerous medical disciplines need to interact. Screening for secondary causes of osteoporosis and the search for new modes of action should present a substantial aspect of osteoporosis management. In the book, the current management of osteoporosis and related metabolic bone diseases is discussed
    Note: English
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  • 70
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564043 , 9783036564050
    Language: Undetermined
    Pages: 1 Online-Ressource (218 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: This reprint aims to promote and disseminate applied research in the field of corrosion of steel structures and technological equipment. Within the text, the focus is firmly placed on the detailed study of corrosion processes affected by specific environments, as well as on the effects of corrosion damage on the reliability and service life of structural components and technological equipment. Special attention is paid to the study of the impact of corrosion processes on pipelines
    Note: English
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  • 71
    ISBN: 9783036566146 , 9783036566153
    Language: Undetermined
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Medicine
    Abstract: When adopting remote sensing techniques in precision agriculture, there are two main areas to consider: data acquisition and data analysis methodologies. Imagery and remote sensor data collected using different platforms provide a variety of information volumes and formats. For example, recent research in precision agriculture has used multispectral images from different platforms, such as satellites, airborne, and, most recently, drones. These images have been used for various analyses, from the detection of pests and diseases, growth, and water status of crops to yield estimations. However, accurately detecting specific biotic or abiotic stresses requires a narrow range of spectral information to be analyzed for each application. In data analysis, the volume and complexity of data formats obtained using the latest technologies in remote sensing (e.g., a cube of data for hyperspectral imagery) demands complex data processing systems and data analysis using multiple inputs to estimate specific categorical or numerical targets. New and emerging methodologies within artificial intelligence, such as machine learning and deep learning, have enabled us to deal with these increasing data volumes and the analysis complexity
    Note: English
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  • 72
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566429 , 9783036566436
    Language: Undetermined
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Medicine ; Oncology
    Abstract: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM
    Note: English
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  • 73
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568119 , 9783036568102
    Language: Undetermined
    Pages: 1 Online-Ressource (346 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasing use of natural-products-based supplements from botanical and marine sources, making their standardization and scientific validation a priority to guarantee the safety of these products. Natural products and/or synthetic derivatives using their novel structures have also been of utmost importance in drug discovery and development in several clinical areas. After a period of discreditation and reduced investment, we are now witnessing a renewed interest from the pharmaceutical industry and scientific community due to the urgent need to develop new drugs. This reprint comprises 11 original and 6 review articles dedicated to plant and marine natural products research, contributing to the scientific validation of their use and opening new perspectives in drug discovery
    Note: English
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  • 74
    ISBN: 9783036567389 , 9783036567396
    Language: Undetermined
    Pages: 1 Online-Ressource (272 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: This reprint focuses on land use/land cover (LULC), natural hazards and their interactions, changes, and impacts. Over the past few decades, the risks due to natural hazards have increased significantly, to a large extent due to changes in LULC, which are triggered mainly by anthropic pressure on landscapes, i.e., urbanization, forest management practices, agricultural practices, and the like. As a result, LULC changes contribute significantly to changes in the variability or magnitude of natural hazards, such as floods, landslides, and erosion. Therefore, this reprint provides a collection of studies focused on the interactions between LULC and different types of natural hazards, which were studied in several research areas around the world
    Note: English
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  • 75
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565811 , 9783036565804
    Language: Undetermined
    Pages: 1 Online-Ressource (304 p.)
    Keywords: Medicine
    Abstract: This reprint brings together fifteen articles published in the Special Issue of the journal Atmosphere, entitled “High-Performance Computing Serving Atmospheric Transport & Dispersion Modelling”. These articles cover a wide variety of topics related to air quality in urban areas and nature-based solutions to improve it in the context of climate change; impact studies on human health and the environment of facilities and infrastructure projects as well as risk studies; the assessment of emerging threats; and preparations for and responses to emergencies involving toxic, flammable, or explosive atmospheric releases. As the fifteen articles presented here remarkably illustrate, what these contemporary topics have in common is the implementation of multi-scale simulations of atmospheric transport and dispersion by means of physical models of computational fluid dynamics (CFDs), whose potential is enhanced by high-performance computing (HPC). This reprint thus addresses the answers provided by modelling and the most advanced simulations to some societal matters of major interest
    Note: English
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  • 76
    ISBN: 9783036564111 , 9783036564104
    Language: Undetermined
    Pages: 1 Online-Ressource (334 p.)
    Keywords: Medicine
    Abstract: Preeclampsia is a hypertensive disorder of pregnancy, diagnosed after the 20th week of gestation in women experiencing new-onset hypertension along with symptoms affecting the liver, kidneys, or brain. In some cases, women with preeclampsia develop novel seizures or unexplained coma, at which time they are diagnosed with eclampsia. The mechanisms contributing to preeclampsia and eclampsia are not fully elucidated, although the placenta seems to play a critical role. Previous studies suggest that improper placentation stimulates mitochondrial dysfunction and the exaggerated release of placental-derived molecules including inflammatory cytokines, anti-angiogenic factors, reactive oxygen species, and cell-free nucleic acids into the maternal circulation that cause systemic vascular dysfunction. These, along with maternally derived molecules, act in concert, leading to hypertension and target organ damage during pregnancies complicated by preeclampsia and eclampsia.In this reprint, we present the original research articles and review papers published as part of the Special Issue: "The Pathophysiology of Preeclampsia and Eclampsia" in Cells
    Note: English
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  • 77
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562636 , 9783036562643
    Language: Undetermined
    Pages: 1 Online-Ressource (186 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Globally, the impact of differentiated thyroid cancers has significantly increased in the last decade, resulting in growth of public health spending. Many international scientific societies are actively involved in the difficult process of building updated guidelines in response to scientific research, especially in the genetic and immunohistochemistry fields. The watch, wait, and see policy has added a new possibility for patients in selected cases. Considering the recognized international interest in this disease, this Special Issue aims to analyze the most recent acquisitions in terms of the diagnosis and therapy of differentiated thyroid cancer. It will offer the reader an updated point of view of the most illustrious endocrinology and endocrine-surgery international schools
    Note: English
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  • 78
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    Baden-Baden : Nomos Verlagsgesellschaft mbH & Co. KG
    ISBN: 9783748935971
    Language: Undetermined
    Pages: 1 Online-Ressource (289 p.)
    Series Statement: Studien zum Handels-, Arbeits- und Wirtschaftsrecht Band 211
    Parallel Title: Erscheint auch als Glombik, Melanie Alina Vorstandspflichten bei verbandsinternen Untersuchungen
    RVK:
    Keywords: LNCD ; Hochschulschrift ; Deutschland Bundesregierung Verbandssanktionengesetz ; Unternehmen ; Compliance-System ; Vorstand ; Gesellschaftsrecht ; USA ; Unternehmen ; Compliance-System ; Vorstand ; Gesellschaftsrecht
    Abstract: Verbandsinterne Untersuchungen sind für die Aufklärung von unternehmensbezogenen Straftaten von erheblicher Relevanz. Ihre Durchführung unterliegt der Verantwortung des Vorstands. Bislang fehlen gesetzliche Vorschriften in Bezug auf die Ausgestaltung und Rechtsfolgen. Die Arbeit geht den Auswirkungen einer im Entwurf gefassten Kodifizierung betreffend verbandsinterne Untersuchungen auf die Pflichten des Vorstands kritisch nach. Dabei werden die vorhandenen Kodifizierungen im US-amerikanischen Recht in den Blick genommen und ein modifizierter Regelungsvorschlag unterbreitet
    Note: German
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  • 79
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563381 , 9783036563398
    Language: Undetermined
    Pages: 1 Online-Ressource (160 p.)
    Keywords: Medicine
    Abstract: Hepatic encephalopathy (HE) is a complex neurological syndrome, characteristic of patients with liver disease, that causes a wide and complex spectrum of nonspecific neurological and psychiatric manifestations, ranging from a subclinical entity such as minimal or covert hepatic encephalopathy to a deep form in which a complete alteration of consciousness can be observed: overt hepatic encephalopathy. Both minimal and overt hepatic encephalopathy have a high impact on patients, caregivers, and national health services, driving substantial consumption of economic resources. In this Special Issue, we discussed the current state-of-the-art research, address ongoing knowledge gaps, and ongoing controversies related to the pathogenesis, diagnosis, and therapeutic management of hepatic encephalopathy
    Note: English
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  • 80
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564678 , 9783036564661
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Medicine
    Abstract: Hyperbaric oxygen is a known therapeutic agent, and treatments using this agent remain a matter of discussion and research. This Special Issue collection will add new knowledge and also offer some not so usual approaches to foster contemporary understanding and potential benefit for patients and scholars
    Note: English
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  • 81
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564470 , 9783036564463
    Language: Undetermined
    Pages: 1 Online-Ressource (178 p.)
    Keywords: Medicine
    Abstract: The majority of newborns do not need medical interventions to manage the neonatal transition after birth. However, every year millions of newborns worldwide require respiratory support immediately after birth, and another considerable number of newborns additionally require extensive resuscitation including chest compressions and drug administration. Despite a significant increase in knowledge and development of enhanced therapy strategies over the past few years, morbidity and mortality caused by failures in neonatal transition remain an important health issue. The purpose of this reprint is to support or introduce novel concepts and add information in the area of the “Stabilization and Resuscitation of Newborns”, aiming to improve neonatal care and, as the major objective, to enhance neuro-developmental outcomes
    Note: English
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  • 82
    ISBN: 9783036562261 , 9783036562254
    Language: Undetermined
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: This reprint contains several articles where the molecular mechanisms and structural changes in target proteins on interaction with various viruses and bacteria were studied. In addition, drug-protein interactions, drug–drug interaction mechanisms, anti-Glycating, antioxidant, binding affinity, network pharmacology-driven investigations, and targeted anticancer treatments were also investigated
    Note: English
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  • 83
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564289 , 9783036564296
    Language: Undetermined
    Pages: 1 Online-Ressource (358 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: Ciguatoxins (CTXs), which are responsible for Ciguatera fish poisoning (CFP), are liposoluble toxins produced by microalgae of the genera Gambierdiscus and Fukuyoa. This book presents 18 scientific papers that offer new information and scientific evidence on: (i) CTX occurrence in aquatic environments, with an emphasis on edible aquatic organisms; (ii) analysis methods for the determination of CTXs; (iii) advances in research on CTX-producing organisms; (iv) environmental factors involved in the presence of CTXs; and (v) the assessment of public health risks related to the presence of CTXs, as well as risk management and mitigation strategies
    Note: English
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  • 84
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562698 , 9783036562704
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: Researchers have made great progress in the mechanism of mycotoxins biosynthesis, pathogenicity, and the construction of detection methods. This collection holds fundamental and applied research on pathogenic fungi and mycotoxins in China, which directly or indirectly affect the health of plants, animals, and humans. Some papers mainly study the mechanism of mycotoxin biosynthesis, including the crucial genes, environmental factors, and regulation mechanisms, which is beneficial to advancing our knowledge of this area. Some papers focus on the toxicity of mycotoxins, which is helpful to the detoxification of mycotoxins and the reduction of the hazardous effect of mycotoxins. Special attention is given to the leading detection methods, especially on-site rapid detection. These effective and feasible methods are important for discovering and controlling the risk of mycotoxins
    Note: English
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  • 85
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561943 , 9783036561936
    Language: Undetermined
    Pages: 1 Online-Ressource (264 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: The rapid expansion of aquaculture around the world is increasingly being impacted by toxins produced by harmful marine microalgae, which threaten the safety of seafood. In addition, ocean climate change is leading to changing patterns in the distribution of toxic dinoflagellates and diatoms which produce these toxins. New approaches are being developed to monitor for harmful species and the toxins they produce. This Special Issue covers pioneering research on harmful marine microalgae and their toxins, including the identification of species and toxins; the development of new chemical and biological techniques to identify and monitor species and toxins; the uptake of marine biotoxins in seafood and marine ecosystems; and the distribution and abundance of toxins, particularly in relation to climate change
    Note: English
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  • 86
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564173 , 9783036564166
    Language: Undetermined
    Pages: 1 Online-Ressource (496 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Advanced Blood-Brain Barrier Drug Delivery is a reprint with a summary editorial, followed by 16 chapters that cover five areas of brain drug delivery, including receptor-mediated transport (RMT), carrier-mediated transport (CMT), active efflux transport (AET), Trojan horse lipid nanoparticles (LNP), and in vivo methods for measurement of drug transport across the blood–brain barrier (BBB)
    Note: English
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  • 87
    ISBN: 9783036563503 , 9783036563510
    Language: Undetermined
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: The objective of this collection is to illustrate the most recent research on the development of novel and/or rapid methods for mycotoxin determination, and to propose new strategies for monitoring and/or reducing mycotoxin contamination. Innovative sample preparation techniques or protocols and the possibility of multiclass mycotoxin detection will be very positively considered for possible inclusion in this Special Issue. Both methods based on (bio)sensors and chromatography with various detectors (including mass spectrometry) are welcome. Applications of already published methods on new matrices without any modification will not be accepted. However, extensive studies and monitoring on the spread of contamination through the food production chain could be of interest for this collection
    Note: English
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  • 88
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568522 , 9783036568539
    Language: Undetermined
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Medicine ; Epidemiology & medical statistics
    Abstract: This reprint focuses on field studies aimed at unraveling the complex networks created by interactions between parasites and hosts in a given ecosystem. Since most transboundary diseases have been propagated from the wilderness to anthropized areas, societies are increasingly concerned about the relevance of wildlife as it pertains to global health. In this respect, research on parasites that may affect the biology and population equilibrium of wildlife is of major interest, especially when a One Health perspective is considered. The studies compiled in the present Special Issue fall within several areas of interest, such as epidemiology, diagnosis, emerging zoonoses, food safety, conservation issues, parasite–host interactions, and the pathology of infections caused by parasites in wild host species
    Note: English
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  • 89
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570037 , 9783036570020
    Language: Undetermined
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Medicine
    Abstract: Steroids are essential hormones that regulate biological processes across their lifespan. Steroid hormone production and action must be tightly controlled otherwise there can be detrimental effects on physiological function leading to disease. This reprint contains original and review articles by experts at the cutting edge of their fields published in a Special Issue on the “Molecular mechanisms of steroid hormone biosynthesis and action” of the International Journal of Molecular Sciences. The topics include: 1) Steroid hormone biosynthesis, including substrate availability, mechanism of steroidogenic enzyme action, and the impact of mutations; 2) Molecular and cellular regulation of steroidogenesis, including steroidogenic cell response to hormone stimulation, signaling pathways, kinases, transcription factors, and gene expression; 3) Molecular mechanisms of endocrine disruptor action on steroidogenic cells; and 4) New tools and approaches to detect and study steroid hormones
    Note: English
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  • 90
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569987 , 9783036569994
    Language: Undetermined
    Pages: 1 Online-Ressource (186 p.)
    Keywords: Medicine ; Neurosciences
    Abstract: The development of in vivo neuroimaging techniques has yielded an incredible amount of digital information about the brain. Neuroimaging techniques are increasingly being used to study human cognitive processes, create brain–machine interfaces, and also to identify and diagnose certain brain disorders. Currently, neuroscientists and medics actively use different methods for brain scans, including electro- and magnetoencephalography (EEG/MEG), functional near-infrared spectroscopy (fNIRS), electrocorticography (ECoG), functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and diffusion tensor imaging (DTI). Recent advances in signal processing and machine learning for neuroimaging data using various signal processing methods have made impressive progress in solving a number of practical tasks in medicine, healthcare, neuroscience, biomedical engineering, brain–machine interfaces, and cognitive science, to name but a few. This Special Issue aims to provide a forum for academic and industrial communities to present and discuss the latest theoretical and experimental results related to recent advances in neuroimaging data processing in terms of new theories, algorithms, architectures, and applications
    Note: English
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  • 91
    ISBN: 9783036566726 , 9783036566733
    Language: Undetermined
    Pages: 1 Online-Ressource (672 p.)
    Keywords: Medicine ; Oncology
    Abstract: This reprint covers some significant impacts in the recent research in both the private and public sectors of cancer diagnosis and therapy, in which Artificial Intelligence (AI) and Machine Learning are significant. This reprint is also a collection of forty different complex and challenging problems arranged in five groups: AI in prognosis, grading, and prediction, AI in clinical image analysis, AI models for pathological diagnosis, ML and statistical models for molecular cancer diagnostics and genetics, and AI in triage, risk stratification, and screening cancer, which are all focused on using AI in cancer diagnosis and therapy. All the necessary concepts, solutions, methodologies, and references are supplied except for some fundamental knowledge that is well-known in the general fields of AI and cancer diagnosis and therapy. The readers may, therefore, gain the main concepts of each chapter, with as little of a need as possible to refer to the concepts of the other chapters and references. The readers may hence start to read one or more chapters of the book for their own interests
    Note: English
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  • 92
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567693 , 9783036567686
    Language: Undetermined
    Pages: 1 Online-Ressource (260 p.)
    Keywords: Medicine
    Abstract: This reprint is an excellent collection of articles that deal with difficult-to-treat infections in the ICU environment. Multiresistant bacteria and fungi create severe treatment problems to the physician charged with their care. We hope that this book will help everyday dilemmas and add useful information on difficult topics
    Note: English
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  • 93
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567846 , 9783036567853
    Language: Undetermined
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Medicine
    Abstract: The Special Issue “Marine Anti-Inflammatory and Antioxidants Agents 2.0” collects in vitro and/or in vivo experimental investigations highlighting the role of marine-derived bioactive compounds as modulators of inflammation and/or oxidative stress, papers describing the mechanisms of action and molecular interactions of compounds isolated from marine organisms, and comprehensive review articles summarizing knowledge on marine anti-inflammatory and/or antioxidant agents in support of human health
    Note: English
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  • 94
    ISBN: 9783036568829 , 9783036568836
    Language: Undetermined
    Pages: 1 Online-Ressource (318 p.)
    Keywords: Medicine
    Abstract: This reprint represents a collection of papers that aimed to highlight the importance of immunohistochemical findings and their role in improving the understanding of organ tissue functions. We focused our attention on farm animals because they represent not only a source of food in the supply chain, but also a source of income for breeders, a source of employment, and a primary tool in the quest for sustainable food production. To achieve this last aim, we asked authors for research that could potentially be applied to the purpose of this study, and whose results could be useful in improving farm management practices and the responsible use of natural resources. A total of 20 papers were contributed to this issue, written by 118 authors from 4 countries, and comprising 18 research articles and 2 communications articles
    Note: English
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  • 95
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571249 , 9783036571256
    Language: Undetermined
    Pages: 1 Online-Ressource (102 p.)
    Keywords: Medicine
    Abstract: The welfare of an individual could be severely affected by stressful events. Mainly for this reason, the scientific community is interested in finding specific and quantifiable characteristics which could indicate or predict specific signs of acute or chronic stress exposure. The aim of this reprint is to reflect this interest in the field of companion animal physiology. The authors engaged in publishing this reprint are experts in the multiple mechanisms involved in stress response, including the detection of behavioral and physical signs which can be measured through biological indicators of homeostasis displacement. The editors strongly believe this topic will be of interest not only to researchers in this field, but also to dog trainers, dog shelter workers and veterinary behaviorists
    Note: English
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  • 96
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574639 , 9783036574622
    Language: Undetermined
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Overcoming biological barriers is a significant challenge in drug development, and recent advancements in drug delivery systems and technologies offer promising solutions. This Special Issue highlights the innovative approaches and techniques being used to improve drug permeability and absorption, as well as their potential impact on a wide range of therapeutic goals. These advancements being made in drug delivery and permeability offer exciting possibilities to improve patient outcomes
    Note: English
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  • 97
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568683 , 9783036568690
    Language: Undetermined
    Pages: 1 Online-Ressource (200 p.)
    Keywords: Medicine
    Abstract: Insects are the most diverse group of organisms, representing approximately 80 percent of the world's species. It is estimated that there are some ten quintillion individual insects alive. During millions of years of evolution, insects developed extraordinary adaptations that allowed them to reside in different habitats. As with all other organisms, insects encounter a wide range of microbes. Although lacking adaptive immunity, they rely on robust innate immune systems to combat these microbes to maintain organismal homeostasis. Conversely, some microbial communities can benefit the host and profoundly affect the host's physiology and overall fitness. Microbiotas have been proven to provide nutrients, promote host defense, and mediate host reproductive behavior. In recent decades, the emergence of high-throughput sequencing has enabled researchers to study host–microbe interactions from the whole microbiome level rather than single microbial species, greatly expanding our knowledge of insect biology
    Note: English
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  • 98
    ISBN: 9783036573519 , 9783036573502
    Language: Undetermined
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Medicine
    Abstract: This reprint emphasizes the perspectives and challenges surrounding COVID-19 and obesity-related cancers, including but not limited to the risk factors of severe COVID-19 in cancer patients; the complications of COVID-19 in cancer patients; the challenges in cancer treatment and surgery; guidelines for cancer care during COVID-19; delayed diagnosis and suboptimal cancer management; the impact of COVID-19 on cancer screening, early diagnosis and cancer presentation; immune response after SARS-CoV-2 infection and vaccination in cancer patients; psychological distress among cancer survivors; telehealth in cancer care; the role of diet and nutraceuticals in the prevention of severe COVID-19 and cancer; and the effects of COVID-19 pandemic on cancer research
    Note: English
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  • 99
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571959 , 9783036571942
    Language: Undetermined
    Pages: 1 Online-Ressource (250 p.)
    Keywords: Medicine ; Mental health services
    Abstract: The aim of the reprint was to provide readers with updated research findings on the psychological and psychiatric consequences of the pandemic. The wide scope of the reprint reflects the complexity of the impact of the COVID-19 pandemic on mental health. The focus of the studies ranges from the psychological consequences of social distancing and the closure of schools to the neurological consequences of the viral infection, and from the stressful impact of an increased workload on frontline health workers to the unmet needs of special populations such as pregnant women, veterans and patients with neurodevelopmental disorders. Thanks to its richness in content and worldwide perspectives (contributors were from Canada, Croatia, Greece, India, Israel, Italy, Pakistan, the Philippines, Poland, Spain, and the USA), the reprint is a valuable source of information to researchers and clinicians interested in the mental health implications of the COVID-19 pandemic
    Note: English
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  • 100
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570617 , 9783036570600
    Language: Undetermined
    Pages: 1 Online-Ressource (304 p.)
    Keywords: Medicine
    Abstract: By joining the two previous editions, this Special Issue completes the trilogy of Special Issues entitled "Biological and Pharmacological Activity of Plant Natural Compounds", which deal with the properties and effects of phytonatural products in preclinical models. This third edition has also remained focused on their therapeutic potential, with the aim of increasing and contributing to the expansion of our scientific knowledge on plants in human health. We hope readers will enjoy this Special Issue as much as the previous publications
    Note: English
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