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  • MPI Ethno. Forsch.  (610)
  • Regensburg UB
  • HBZ
  • Online-Ressource  (610)
  • Unbestimmte Sprache  (610)
  • Arabisch
  • Niederländisch
  • Biology, life sciences  (610)
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  • MPI Ethno. Forsch.  (610)
  • Regensburg UB
  • HBZ
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  • Online-Ressource  (610)
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  • 1
    Online-Ressource
    Online-Ressource
    Cham : Springer Nature
    ISBN: 9783031389689 , 9783031389672
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (333 p.)
    Serie: History, Philosophy and Theory of the Life Sciences
    Schlagwort(e): Philosophy ; Biology, life sciences
    Kurzfassung: This open access book assesses the prospects of (re)adopting organization as a pivotal concept in biology. It shows how organization can nourish biological thinking and practice, by reconnecting with the idea of biology as the science of organized systems. The book provides a comprehensive state-of-the-art picture of the characterizations and uses of the concept of organization in both biological science and philosophy of biology. It also deals with a variety of themes – including evolution, organogenesis, heredity, cognition and ecology – with respect to which the concept of organization can guide the elaboration of original models and new experimental protocols. It will be of interest to biologists and scholars working in philosophy of science alike
    Anmerkung: English
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  • 2
    ISBN: 9781032286747 , 9781032286754
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (24 p.)
    Schlagwort(e): Biology, life sciences
    Kurzfassung: In arid and semiarid landscapes, water is the primary limiting resource for human activity and ecosystem functioning. More than 40% of the world’s population lives in dryland environments (White and Nackoney, 2003). In these landscapes annual rainfall can vary greatly and be highly unpredictable both in space and time. Longer intervals between precipitation events are also highly erratic and global atmosphere-ocean teleconnections—such as unusually cool Pacific Sea surface temperatures during the La Niña phase of the El Niño -Southern Oscillation can trigger multi-decadal “megadroughts” (McCabe et al., 2004; Cook et al., 2016; Routson et al., 2016; Steiger et al., 2019). Soil moisture and local ecohydrology constrain the extent and intensity of food production possible through agriculture. Complex combinations of social and physical infrastructure have sustained population growth and managed hydroclimate risks in the past. Indigenous soil and water conservation has been tested over millennia to support agriculture (Johnson et al. 2021)
    Anmerkung: English
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  • 3
    ISBN: 9783832557515
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (215 p.)
    Serie: Wissenschaftliche Beiträge zur Medizinelektronik 11
    Schlagwort(e): Mathematics and Science ; Science: general issues ; Physics ; Chemistry ; Biology, life sciences ; Energy technology and engineering ; Electronics and communications engineering ; Computer science ; Cells distinction ; Electrical Impedance Spectroscopy ; Metastatic cancers ; Non-metastatic cancers ; Cell charge
    Kurzfassung: Bio Impedance Spectroscopy (BIS) consists in the application of a small frequency variable electrical signal to a biological material and measuring its response. This research explores BIS applied to cancer and healthy cells and tissues, with the objective to try to distinguish them and also to explore differences between metastatic and non-metastatic cancers. Important trends were found in the direction of a significant different spectral response between cancerous and healthy tissues, close correlated with the effects of the cancer in the normal tissues. Also, one physical characteristic that can possibly be used to distinguish metastatic from non-metastatic cancer cells was found: the cell surface charge
    Anmerkung: English
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  • 4
    ISBN: 9783662679081 , 9783662679074
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (337 p.)
    Schlagwort(e): Biology, life sciences ; Genome Editing ; Keimbahnmodifikation ; Genetisches Enhancement ; Vektoren ; Immuntherapie ; Stammzelltransplantation
    Kurzfassung: Wenn Sie sich für den Stand der Dinge auf dem Gebiet der Gen- und Zelltherapie interessieren, bietet Ihnen diese Open-Access-Publikation einen umfassenden und hochaktuellen Überblick. Wissenschaftler und Experten behandeln Fragen wie: Haben CAR-T-Zellen etwas mit Autos zu tun, wie funktionieren Genfähren, können uns Stammzellen bei Therapien helfen, was sind Organoide und warum dauert es oft so lange, bis neuartige Behandlungskonzepte in die Klinik kommen? Kann man Gene wie Bücher editieren, wie gefährlich ist das eigentlich und wer kontrolliert sowas, muss Gentherapie so teuer sein und ist sichergestellt, dass alle Patienten die Therapie bekommen, die sie benötigen?
    Anmerkung: German
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  • 5
    Online-Ressource
    Online-Ressource
    [Erscheinungsort nicht ermittelbar] : Taylor & Francis
    ISBN: 9781032409023 , 9781032409061
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (13 p.)
    Schlagwort(e): Immunology ; Clinical & internal medicine ; Molecular biology ; Cellular biology (cytology) ; Biology, life sciences ; asthma; cystic fibrosis; gas exchange; homeostasis; inflammation; lung diseas; lung endothelium;stem cells
    Kurzfassung: ch. 8 Post-translational modification (PTMs) determines protein’s cellular functions including enzyme activity, localization, protein-protein interaction, and protein stability. Ubiquitin is a 7-kDa protein. Ubiquitination is one of PTMs and it is defined as protein covalently conjugation with a ubiquitin or poly-ubiquitin chains. A series of enzymatic reactions catalyze protein ubiquitination, which can be reversed by deubiquitinating enzymes (DUBs). The abnormal expression of ubiquitination-related enzymes and ubiquitination in lung cells have been demonstrated to alter cell functions, such as cell proliferation, death, and differentiation, ultimately contribute to the pathogenesis of lung diseases. In this chapter, we will introduce the methodology and research strategies for investigating protein ubiquitination in lung cells and experimental lung diseases. Common practice and edge-cutting laboratory technologies will be introduced in the chapter. Finally, we will discuss new drug development by targeting ubiquitination for therapies
    Anmerkung: English
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  • 6
    Online-Ressource
    Online-Ressource
    [Erscheinungsort nicht ermittelbar] : Taylor & Francis
    ISBN: 9781032286747 , 9781032286754 , 9781003297932
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource
    Serie: Advances in Soil Science
    Schlagwort(e): Biology, life sciences ; Biology; life sciences
    Kurzfassung: Drought, a serious global issue, is being aggravated by climate change. Both pedological and agronomic droughts are a major risk factor with adverse effects on agronomic productivity, food and nutritional security, and human wellbeing
    Anmerkung: English
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  • 7
    Online-Ressource
    Online-Ressource
    [Erscheinungsort nicht ermittelbar] : Taylor & Francis
    ISBN: 9781032409023 , 9781032409061 , 9781003355243
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource
    Schlagwort(e): Immunology ; Clinical & internal medicine ; Molecular biology ; Cellular biology (cytology) ; Biology, life sciences ; asthma; cystic fibrosis; gas exchange; homeostasis; inflammation; lung diseas; lung endothelium;stem cells
    Kurzfassung: asthma; cystic fibrosis; gas exchange; homeostasis; inflammation; lung diseas; lung endothelium;stem cells
    Anmerkung: English
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  • 8
    Online-Ressource
    Online-Ressource
    [Erscheinungsort nicht ermittelbar] : Taylor & Francis
    ISBN: 9781032409023 , 9781032409061
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (29 p.)
    Schlagwort(e): Immunology ; Clinical & internal medicine ; Molecular biology ; Cellular biology (cytology) ; Biology, life sciences ; asthma; cystic fibrosis; gas exchange; homeostasis; inflammation; lung diseas; lung endothelium;stem cells
    Kurzfassung: ch. 13 Traditional Chinese medicine (TCM) is a brilliant component of Chinese culture with more than three thousand years of history. The ancient Chinese philosophical thought brought TCM a unique theoretical system that is the guiding principles of “holism” and “syndrome differentiation and treatment.” Chinese herbal medicine, a particularly important component of the whole TCM, has been utilized to treat and prevent various diseases including respiratory diseases. In the present chapter, we will briefly describe the treatment strategies of Chinese herbal medicines for five lung diseases from the modern scientific perspective. We will discuss the following diseases: viral infection (specifically SARS-COV-2 infection, the major disease currently prevalent), acute lung injury/acute respiratory distress syndrome, bronchial asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. We have collected relevant literature and described some representative TCM formulas and their compositions, known chemical ingredients in some important herbs, and possible mechanisms of action for treating these diseases. The Chinese herbal medicines can act on various inflammatory cells, immune cells, and even structural cells, and enable them directly or indirectly to act on biomolecules in the body, such as enzymes and mediators of signaling pathways. The medicines can play roles in anti-inflammation, anti-oxidation, immunomodulation, anti-airway remodeling, anti-pulmonary fibrosis, regulation of water, electrolytes, acid-base balance, hormone agonist/antagonist-like effects, and so on, in effort to achieve the goal of treating both symptoms and root causes. TCM has its unique effectiveness and advantages in treating and preventing diseases, and it is receiving attention from the medical community around the world. However, TCM, after all, is an ancient traditional medicine that emerged in an era of relatively backwards productivity. Its theory and application are subject to certain limitations, and there is an urgent need to conduct in-depth research and organization using modern scientific methods. Practice has proven that the combination of TCM and Western medicine can produce significant therapeutic effects on diseases compared to using any medicine alone. The purpose of this chapter is to introduce and deepen people's understanding, interest, and identification with TCM, and to further research and development to modernize TCM and integrate it with Western medicine for the benefit of humanity
    Anmerkung: English
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  • 9
    ISBN: 9783031393556 , 9783031393549
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (810 p.)
    Serie: Health Informatics
    Schlagwort(e): Medical equipment and techniques ; Information technology: general topics ; Nursing and ancillary services ; Computer science ; Biology, life sciences ; Public health and preventive medicine ; Predictive analytics ; Artificial intelligence ; Medicine ; Machine learning ; Causal discovery ; Causal inference ; Genomics ; Medical knowledge discovery ; Clinical risk models ; Clinical risk stratification
    Kurzfassung: This open access book provides a detailed review of the latest methods and applications of artificial intelligence (AI) and machine learning (ML) in medicine. With chapters focusing on enabling the reader to develop a thorough understanding of the key concepts in these subject areas along with a range of methods and resulting models that can be utilized to solve healthcare problems, the use of causal and predictive models are comprehensively discussed. Care is taken to systematically describe the concepts to facilitate the reader in developing a thorough conceptual understanding of how different methods and resulting models function and how these relate to their applicability to various issues in health care and medical sciences. Guidance is also given on how to avoid pitfalls that can be encountered on a day-to-day basis and stratify potential clinical risks. Artificial Intelligence and Machine Learning in Health Care and Medical Sciences: Best Practices and Pitfallsis a comprehensive guide to how AI and ML techniques can best be applied in health care. The emphasis placed on how to avoid a variety of pitfalls that can be encountered makes it an indispensable guide for all medical informatics professionals and physicians who utilize these methodologies on a day-to-day basis. Furthermore, this work will be of significant interest to health data scientists, administrators and to students in the health sciences seeking an up-to-date resource on the topic
    Anmerkung: English
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  • 10
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567198 , 9783036567181
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (226 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Microgrids deliver efficient, low-cost, and clean energy while improving regional electric grid operation and stability. They further provide exceptional dynamic responsiveness for energy resources. A global portfolio of operations centered on the development and deployment of microgrids to increase grid dependability and resilience would therefore assist communities in better preparing for future weather catastrophes and keep the world moving toward a sustainable energy future. Solar photovoltaic systems are seen as a promising renewable resource, and their application in microgrids has grown rapidly in recent years
    Anmerkung: English
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  • 11
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566818 , 9783036566801
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (252 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Botany & plant sciences
    Kurzfassung: This reprint includes a collection of up-to-date articles on epidemiology, prevention, diagnosis and treatment of melanoma, basal cell carcinoma, squamous cell carcinoma and Merkel cell carcinoma. It also includes items on the use of artificial intelligence for skin cancer diagnoses as well as the impact of new immunotherapies on patient's quality of life
    Anmerkung: English
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  • 12
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564975 , 9783036564982
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (172 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Ecological science, the Biosphere
    Kurzfassung: This issue contains contributions in different cutting edge topics within the field of open quantum systems. The theoretical work presented is focused, in particular, on quantum thermodynamics and quantum non-Markovianity and provides a window into current research in these fields. Different perspectives are considered that share a common root in the exploitation of open quantum systems and quantum information tools
    Anmerkung: English
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  • 13
    ISBN: 9783036566764 , 9783036566771
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (262 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: The reprint “Sustainable Healthy Working Life for All Ages—Work Environment, Age Management and Employability” provide an outlet of research contributing to the development of theoretical and practical knowledge influencing people’s working life. Working life is complex and there are many different factors that influence, such as the demographic change, pandemic and rapid technological development, etc., which place constantly changing demands on both employees, organizations/companies and society in different countries. This reprint covers new knowledge, as identified factors and areas that affect employees' ability to work to an older age, interventions and measures that enable a healthy and sustainable working life throughout the entire working life journey, from young to senior employees. The reprint also addresses the pressured work situation of school leaders in managing the education of children and young people in society, and what makes them stay or leave their jobs. In addition, the reprint addresses the way in which the Covid-19 pandemic has affected working life, not least for the health care professional groups and organizations
    Anmerkung: English
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  • 14
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568263 , 9783036568270
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (246 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: It is crucial that scientists and engineers develop their expertise and capability through research and practice to quantify the interaction of infrastructure with the surroundings and the ground upon which they are founded. Therefore, the engineering concept ‘soil–structure interaction’ forms an integral part of delivering successful project outcomes. As the Lead and Honorary Editor for this Special Issue, Soil–Structure Interaction, I cordially invited the submission of esteemed articles related to recent projects, research, or case studies. These articles detail how geosciences (soil, rock, ground water, geochemistry, geology, hydrogeology, surface run-off, rain, wind, and temperature) directly interact with and impact the performance of human-made structures, buildings, or infrastructure through the following aspects: i) Underground construction; ii) Innovative ground improvement methods; iii) Geological explorations and interpretation; iv) Instrumentation and field observational method; v) Use of artificial intelligence or algorithms; vi) Forensic engineering or inverse-analysis methods; vii) Geophysical methods for soil or rock characterization; viii) Advancement in laboratory and field testing of geomaterials; ix) Advancement in numerical analysis; x) Advancement in multi-disciplinary design theories, codes of practice, and engineering education
    Anmerkung: English
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  • 15
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567211 , 9783036567204
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (244 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: The reprint provides the most relevant and state-of-the-art in the field, including recent developments in the production of natural compounds from various bioresources, and their formulations as bioactives. This reprint also covered the engineered approaches for enhanced biological properties and their potential applications. Identification of novel compounds and bioprocess tools to improve the quantity and quality of bioactive compounds and their formulations are exclusively covered in this reprint
    Anmerkung: English
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  • 16
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568157 , 9783036568140
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (246 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: The researchers involved in this reprint will continue their studies to improve the existent dental biomaterials in order to achieve optimal dental treatment with biocompatible, bioactive, and stable properties. As the Guest Editors, we sincerely value and thank the reviewers for their insightful comments and the support of the team at Bioengineering. Finally, we express our gratitude to all contributing authors for their valuable research. Altogether, the 16 research papers/reviews in this Special Issue entitled "Recent Advances in Biomaterials and Dental Disease" reflect the importance of in vitro and in vivo studies for improving the efficacy of using biomaterials in dental treatment
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  • 17
    ISBN: 9783036564777 , 9783036564784
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: Over the last 50 years, people’s lives and health have been increasingly defined and influenced across the life course and across levels of influence by different processes of medicalization and social control. Although medicalization is not a new concept, new actors, in addition to medical professionals and patients, and new phenomena, such as consumerism and human enhancement, influence the processes of the transformation of human conditions into medical problems today. This reprint integrates several articles that stimulate reflexivity on the use of the concept of medicalization. The articles selected for this reprint, written by research experts in their topic of interest, contribute to the discussion on the wide variety of ethical issues that arise from medicalization processes in areas ranging from medical research conduct to reproductive health. The reader will find a fertile space for theoretical and empirical reflection, where several social science researchers with different backgrounds share their research rigorously and innovatively
    Anmerkung: English
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  • 18
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568003 , 9783036568010
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (290 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: This reprint is mainly aimed at economists involved in the energy market. Energy market processes have an enormous impact on people's day-to-day economic activities. The economics of sustainability leads the way in theorizing how best to prevent environmental degradation whilst also fostering positive economic development. For these reasons, the focus of this reprint is mainly on pollution and the energy transition. Works on energy resources and future-oriented solutions that reduce the consumption of classical energy resources are explored in the reprint. Papers relating to contemporary accounting and the stock market are also presented. The geographical area of the works showcased here essentially covers the entire eastern hemisphere of the globe (Asia, Africa and Europe). They are mainly empirical studies, although in one case a bibliometric analysis is included
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  • 19
    ISBN: 9783036568751 , 9783036568744
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (162 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: Taurine (2-aminoethanesulfonic acid) has been reported to have a lot of physiological and pharmacological functions in various tissues, cells, and organelles in many species since discovered in the gall bladder of bovine in 1827, and its novel functions and roles have now been focused in many fields. This Special Issue consisted of eight original and two review articles contains the newest findings on the roles of taurine as an essential nutrient for development and growth in fetuses and infants, and functional maintenance in the brain, skeletal muscles, and others in adults, in mammalian, chicken, and fish
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  • 20
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565132 , 9783036565149
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (128 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19), posing a new challenge to the medical care of solid organ transplant (SOT) recipients. Due to the relatively small number of studies in SOT recipients suffering from COVID-19, the natural course of the SARS-CoV-2 infection, optimal treatment strategies including modification of immunosuppressive therapy and the prognosis in COVID-19 in these patients is incompletely understood. The current Special Issue aimed to fill some of the knowledge gaps and highlight some recent advances in the management of SOT patients during the pandemic. The call for manuscripts had been addressed to healthcare professionals involved in SOT patient care. We welcomed comprehensive reviews, original studies, interesting case series or case reports and commentaries relating to this topic
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  • 21
    ISBN: 9783036565255 , 9783036565262
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (216 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint discusses advancements in forest research using Earth Observation datasets. Forests, which occupy about one-third of the terrestrial surface of Earth, play an indispensable role in monitoring global climate change and ecosystem dynamics. The health of forests has been affected in recent years by various stress factors, such as forest fragmentation and deforestation, biodiversity loss, climate change, invasive species, drought, and unsustainable management. This reprint focuses on the evaluation of different techniques for the retrieval of different biophysical/biochemical parameters using available Earth Observation data. The following topics have been covered in this reprint: Mangrove forest carbon assessment using EO data; Phenological ,etrics of plant species using NDVI time series data; fPAR for diversity relation; Forest/canopy height retrieval using Pol-InSAR modeling; Dominant species discrimination using LiDAR data; Biophysical parameters estimation of young oil palm using UAV
    Anmerkung: English
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  • 22
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565330 , 9783036565347
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (244 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: Considering the worldwide problem of aquatic pollution, we proposed this reprint, which presents a collection of articles on different aspects of environmental pollution, from monitoring to the evaluation of toxicity. In particular, the volume concerns the issues specifically related to emerging contaminants in aquatic environments, such as plastics and pharmaceuticals. However, to confer to this volume a more holistic view, some articles on priority pollutants, such as heavy metals and pesticides, are also reported
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  • 23
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566795 , 9783036566788
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (252 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Ecological science, the Biosphere
    Kurzfassung: This Special Issue on MNEs, sustainability, and innovation contains a collection of 13 papers that address several subjects that are on related themes. The authors of these contributions study the boundaries of the previous literature on these relevant topics by providing insightful findings and review, as well as proposals for future research ideas in various contexts. For this Special Issue, we invited both conceptual and (qualitative and quantitative) empirical articles, as well as literature reviews and meta-analysis articles from a range of fields; these included not only business and management, but also sociology, political science, psychology, economics, and economic geography, among others
    Anmerkung: English
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  • 24
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565712 , 9783036565705
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (134 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Ecological science, the Biosphere
    Kurzfassung: The introduction of permanent cardiac pacing in the late 1950s began the era of cardiac electrotherapy. In the 1980s, implantable cardioverter defibrillators (ICDs) were introduced. These advances created new challenges for cardiac implantable electronic devices (CIEDs). Right ventricular pacing was the primary breakthrough; however, over the years, it has become apparent that it can induce cardiac contraction dyssynchrony. Biventricular pacing allowed for the alleviation of dyssynchrony and improved the survival of patients with heart failure and bundle branch block. In recent decades, His bundle pacing has become a new strategy for physiological ventricular activation. However, the use of CIEDs carries several risks, e.g., complications related to transvenous leads. This led to the development of percutaneous lead extraction techniques as well as the introduction of a subcutaneous ICD (S-ICD) and leadless pacing. Technological evolution promises an exciting future in the development of cardiac electrotherapy.In this Special Issue, readers can find out about the clinical and hemodynamic aspects of right ventricular, His bundle, and biventricular pacing; ICD therapy; treatment of complications and technological advances in cardiac electrotherapy
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  • 25
    ISBN: 9783036568423 , 9783036568430
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (312 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: This reprint focuses on fundamental and applied research involving the combination of biomaterials and cancer cells to develop a three-dimensional (3D) tumor microenvironment in vitro, in which carcinogenesis mechanisms can be studied and therapies can be screened. Such models are becoming quite popular within the bioengineering community; thus, many technologies are being tested to obtain the best scaffold for each tumor. In any case, only a tight interaction of bioengineers with cancer biologists and oncologists can make such 3D models progress, with them finally reaching a clinical relevance. On the other hand, the medical community is approaching simpler 3D in vitro models not provided with sufficient extracellular matrix biomimicry, such as spheroids and organoids, which may not be self-exhaustive; therefore, cancer researchers could benefit from closer contact with bioengineers. The aim of this reprint is to help generate shared knowledge and promote strong interdisciplinary collaboration with the ultimate goal of contributing to the acceleration of the discovery and validation of more precise therapies to fight cancer
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  • 26
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568676 , 9783036568669
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (234 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Zoology & animal sciences
    Kurzfassung: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy
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  • 27
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568843 , 9783036568850
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (226 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: Many cancer diagnosis and treatment modalities have been developed over time, among which radioisotopes have been widely used. Recently, with the application of magnetic nanoparticles, a wide range of non-invasive diagnosis and treatment methods using magnetic techniques have attracted attention. This Special Issue introduces a lymph node biopsy method with a magnetic probe for the treatment of cancer, rapid immunostaining using magnetic nanoparticles in pathological diagnosis, cancer imaging with MRI (magnetic resonance imaging)/MPI (magnetic particle imaging), magnetic hyperthermia for cancer treatment, and the development of magnetic nanoparticles
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  • 28
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566689 , 9783036566696
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (152 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: The reprint provides an overview of recent applications of both chemometrics and spectrometric techniques to target current issues associated with food authenticity, traceability, as well as modern approaches on the analysis of food ingredients and products
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  • 29
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565439 , 9783036565422
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (256 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Fisheries & related industries
    Kurzfassung: Composites can be engineered to exhibit high strength, high stiffness, and high toughness. Composite structures have increasingly been used in various engineering applications. In recent decades, most fundamentals of science have expanded in length by many orders of magnitude. Nowadays, one of the primary goals of science and technology seems to be to develop reliable methods for linking the physical phenomena that occur over multiple length scales, particularly from a nano-/microscale to a macroscale. To engineer composites for high performance and to design advanced structures, the relationship between material nano-/microstructures and their macroscopic properties must be established to accurately predict their mechanical performance and failure. Multiscale simulation is a tool that enables studying and comprehending complex systems and phenomena that would otherwise be too expensive or dangerous, or even impossible, to study by direct experimentation and, thus, to achieve this goal.This reprint assembles high-quality chapters that advance the field of the multiscale simulation of composite structures, through the application of any modern computational and/or analytical methods alone or in conjunction with experimental techniques, for damage assessment or mechanical analysis and prediction
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  • 30
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036566320 , 9783036566337
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (286 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies
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  • 31
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561264 , 9783036566412
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (376 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint focuses on PLA-based materials and the modification of their properties for biomedical applications. Special emphasis is placed on the supramolecular strategies that lead to unique structures in the micro- or nanoscale. The development and testing of novel biomaterials as drug delivery carriers, implants, or tissue engineering scaffolds are of particular interest. Special attention is given to understanding the structure–properties relationship, since this allows for the development of the most effective biocompatible materials
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  • 32
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036520940 , 9783036520933
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (186 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Fungi-induced stains on paper are one of the most challenging forms of biodeterioration to study and to prevent; this is because they involve living organisms, and the ways in which fungi respond to changes in the environment and modifications of paper are unpredictable. Yet, there is a great desire among those who encounter fungi on documents, manuscripts, or artwork to remove fungi and clean the paper. This experience in most cases is particularly challenging. What are the reasons behind this challenge? This ground-breaking book attempts to answer this question, among others, by exploring the complex interfacial forces between paper, fungi, and their pigmented secretions which result in bio-stains on paper. Black fungi, collectively referred to as Dematiaceous fungi, were used in this study as a subset of pigment-producing fungi species. The focus is on two, under-studied aspects of the fungi infestation of paper, an interface of fungal pigments and paper, and the impact of light on the production of fungi bio-stains. The results of analytical testing included in this book elucidate the synergistic interactions between the environment, biological clocks of the microorganisms, and secretion of fungal pigments to paper. The black fungal pigment formation is explored in-depth in two scenarios: one that is ‘natural’, when the bio-stains of original artworks have occurred over time by chance, and another, induced by Aspergillus niger, in bio-simulation on known papers in a controlled environment. The findings are intended to provide guidance for preservation strategies, mitigating the biodeterioration of paper, and designing conservation treatment when applicable. The surface of artworks and artifacts is of great aesthetic and artistic importance; conversely, it plays a significant role in governing fungal attachments. In this book, the paper surface is characterized in detail and in correlation with chemical and physical alterations caused by fungal pigmentation. A broad range of analytical instruments was used for surface characterization, such as surface metrology profilometers, a confocal laser scanning microscope, and environmental scanning electron microscope; chemical microanalysis was carried out using X-ray energy dispersive spectroscopy. The novel, three-dimensional characterization of pigmented fungal inclusions and their interaction with paper matrix was studied with micro-X-ray-computed micro-tomography on the synchrotron ESRF. The proposed book is the first to explore the complexity of fungal–paper interactions with the intention to assist professionals working with cultural materials, especially paper-based materials, to make informed decisions when dealing with the fungi infestation of paper
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  • 33
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    [Erscheinungsort nicht ermittelbar] : Taylor & Francis
    ISBN: 9781003109242 , 9781000623086 , 9780367623920 , 9780367567781
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (400 p.)
    Schlagwort(e): Molecular biology ; Cellular biology (cytology) ; Genetics (non-medical) ; Microbiology (non-medical) ; Biochemistry ; Organic chemistry ; Biotechnology ; Biology, life sciences ; Biophysics
    Kurzfassung: The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers
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  • 34
    ISBN: 9783036559674 , 9783036559681
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (vii, 211 Seiten)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Sundqvist, Sandlund, Källkvist, and Gyllstad have edited a timely reprint that will help to guide the future of English language teaching and learning. This comprehensive and lucidly written volume brings together research on English classroom practices from all levels across the globe with the aim of enhancing our understanding of current developments. All chapters are theoretically informed, as the reprint is both practical in its style and orientation, and pedagogically astute in the recommendations offered. This volume is a welcome resource for teachers, student teachers, teacher educators and researchers around the world
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  • 35
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561219 , 9783036561226
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (318 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Systemic sclerosis (scleroderma) is an incurable connective tissue disease with an unclear etiology characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, digestive tract, heart, and kidneys. The collection of six original research manuscripts and five review articles included in this book highlights the most recent advances in this field and provides further elucidation of the pathogenesis, natural disease course, and treatment of this challenging disease
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  • 36
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036556659 , 9783036556666
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (220 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: Consumers and stakeholders are increasingly demanding that the meat industry guarantees high-quality meat products with stable and acceptable sensory and safety properties. To do this, it is necessary to understand the mechanisms that underlie the conversion of muscle into meat, as well as the impact of pre- and post-harvest procedures on the final quality and safety of meat products. Over the last two decades, sophisticated OMICs technologies—genomics, transcriptomics, proteomics, peptidomics, metabolomics and lipidomics, also known as foodomics—have been powerful approaches that extended the scope of traditional methods and have established impressive possibilities of addressing meat quality issues. Foodomics were further used to elucidate the biological basis/mechanisms of phenotypic variation in the technological and sensory quality traits of meat from different species. Overall, these techniques aimed to comprehensively study the dynamic link(s) between the genome and the quality traits of the meat that we eat compared to traditional methods, hence improving both the accuracy and sensitivity thanks to the large quantities of data that can be generated. This Special Issue focused on the cutting-edge research applications of OMICs tools to characterize or manage the quality of muscle foods. The research papers applied transcriptomics, targeted and untargeted proteomics, metabolomics, and genomics, among others, to evaluate meat quality, determine the molecular profiles of meat and meat products, discover and/or evaluate biomarkers of meat quality traits, and to characterize the safety, adulteration, and authenticity of meat and meat products
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  • 37
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036558677 , 9783036558684
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (90 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Filter-feeding in marine invertebrates is a big and important research subject, which cannot be even approximately covered by the present six articles. But although these articles deal with a limited and rather random selection of both topics and filter-feeding species, they give an update of certain aspects of important ongoing research. The articles deal with many topics, such as: filtration rates, energy budgets, growth rates, bioenergetic modeling, filter-pump design, particle-capture mechanisms, functional morphology, and hydrodynamics studied in sponges, jellyfish, mussels, and other filter-feeding marine invertebrates. This makes the Special Issue relevant for all marine biologists
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  • 38
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036563336 , 9783036563329
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (236 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: This reprint collects high-quality manuscripts with a focus on food composition, with special emphasis on chemical characterization, the content of bioactive molecules, contaminants, and analytical aspects. The roles of variety, cultivation, growing conditions, and technological processes on the nutritional quality of foods have been investigated. Studies dealing with the biological activity and health benefits of bioactive food molecules have been also considered
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  • 39
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562650 , 9783036562667
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (244 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: At present, the increasing demand for novel biotechnological products is supported through the continuous development of biocatalytic applications. As a consequence, the progress of research regarding enzymatic catalysis in aqueous, non-aqueous, organic (polar or non-polar), and/or non-solvent media is decisive. Experimental design methods, which also may comprise in silico studies, the design of specific reactors and conditions, the reactions of significant chemical and/or biochemical processes that are relevant to industrial production, enzyme kinetic methods, the investigation of enzymatic mechanisms and the use of immobilized enzymes and/or microbial cells on various inert matrices, are all useful. A plethora of enzymes of several classes, which may potentially be used as biocatalysts in biotechnological applications, are available. Among these enzymes, the more common are oxidoreductases (laccase, catalase, glucose oxidase, etc.), hydrolases (amylases, lipases, proteases, amidases, cellulases, esterases, etc.), isomerases (epimerases, topoisomerases, mutases, etc.), and others. By means of the aforementioned biocatalysts and the utilization of specific biotechnological methods, important, cost-effective, sustainable, and environmentally friendly processes have been applied for the synthesis and/or the conversion of a huge number of market-required products
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  • 40
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565019 , 9783036565026
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (238 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Forestry & related industries
    Kurzfassung: This reprint highlights the ecological importance of forest litter in nutrient cycling, the sequestration of soil carbon, and the formation of soil organic matter. The results presented would be of great importance for the improvement of forest services against the background of the global climate change scenario
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  • 41
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570754 , 9783036570747
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (262 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases characterized by neuronal loss and progressive degeneration of different areas of the nervous system. NDs represent a significant health problem worldwide, with an increasing incidence rate. Although the exact pathogenesis of NDs remains unclear, a complex interaction among genetic, epigenetic, and environmental factors has been proposed. To date, no effective therapeutics have been developed to slow, halt, or prevent any NDs. Thus, information on the molecular mechanisms underlying the pathogenesis of NDs is strongly sought after. This Special Issue collected papers discussing advances in the field of NDs
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  • 42
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036564951 , 9783036564968
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: This reprint focuses on fungi as they are considered one of the most harmful organisms, endangering the conservation of historical and artistic heritage worldwide. Fungi are a large group of organisms occupying many ecological niches, even those considered extreme, due to their ability to cope with many environmental factors and to feed on all organic materials, even those considered toxic. For these reasons, the conservation of artefacts of historical or artistic value must consider information on fungal diversity, ecology, and the methods of controlling or limiting their destructive action. Biocides have been used for decades as the method of choice to stop or mitigate fungal spreading when preventive measures fail. Recently, more attention has been paid to alternative control methods that are more respectful of the operator and the environment. Due to the wide range of materials used throughout history, and the microclimatic conditions to which they are subjected worldwide, more efforts are needed to cover this knowledge gap and set more sustainable protocols
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  • 43
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571263 , 9783036571270
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (304 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint focuses on the most recent technical innovations and developments in the area of microfluidics, particularly in relation to their biomedical applications. The advent of microfluidics has provided important insights into the fields of biomedical research and clinical diagnosis. Special attention is given to the isolation and detection of circulating tumor cells and exosomes, the generation of concentration dilutions, the rapid sensing and detection of single molecules and viruses, and the innovations in inertial microfluidics, electrical impedance, magnetic biosensors, and droplet microfluidics
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  • 44
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036570204 , 9783036570211
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (238 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: This reprint describes the ability of some foods or natural substances extracted by plants to counteract some of the most common diseases at present, such as obesity, diabetes, intestinal inflammatory diseases, and neurodegeneration. It is well accepted that high-fat diets that are rich in saturated fats are involved in the onset and progression of obesity and its dangerous comorbidities. It is also well accepted that a balanced diet is useful to maintain a good health status and the choice of certain foods could help to counteract the onset of chronic diseases. Foods and natural substances rich in compounds with anti-inflammatory and antioxidant properties should be paid attention. Most of these foods belong to the Mediterranean Diet, and they are famous for being rich of unsaturated fatty acids, such as the oleic acid found in extra-virgin olive oil, or the omega 3 contained in fish, vitamin D and vitamin C with their high anti-oxidant capacity, and spices and nuts that can counteract inflammatory status. These substances have also anti-obesity properties, because they are able to reduce fat mass and and restore the physiological role of fat tissue. Therefore, strict adherence to this healthy diet could be enough to prevent the onset of chronic diseases linked to fatty diets or aging. The scientific data collected in this reprint could provide new insights, allowing for readers to change their own dietary habits and make more informed food choices
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  • 45
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569956 , 9783036569949
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (202 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Botany & plant sciences
    Kurzfassung: Microalgae are photosynthetic unicellular microorganisms that represent an extremely important component of the aquatic ecosystem productivity, diversity, and functioning. Moreover, these microorganisms, using a network of signals, interact with all the other organisms present in their environment. Signals are often secondary metabolites that play an important role in competition, defense, attraction, and signaling. These molecules are recognized for having bioactive properties, but some of them are still largely underexplored and underexploited. This Special Issue focuses on studies aimed to improve knowledge on microalgal ecology (diversity and dynamics) in aquatic ecosystems, as well as on their capacity to produce bioactive compounds with potential biotechnological applications
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  • 46
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567440 , 9783036567457
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (240 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: Organic carbon (OC), nutrients and trace metals are key aquatic components of freshwater systems, including groundwater, soil water, lakes, rivers, and their estuaries. Over the past decade, there has been increasing interest regarding the rising in organic carbon and iron concentrations in freshwaters in relation to the so-called “browning” effect, caused by climate warming and changes in anthropogenic pressure. As for phosphorus, it is a vital element for all aquatic ecosystems and its aquatic biogeochemical cycle now undergoes sizable changes linked to eutrophication, invasive species development, and transformations between organic and inorganic forms. This book combines the articles dedicated to various aspects of the behavior of organic carbon, phosphorus, iron (and other related metals) in a broad range of freshwater environments, from soil solutions and groundwaters to ponds, lakes, rivers, and their riparian zones and estuaries
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  • 47
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569734 , 9783036569727
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (392 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Adaptation to external changes is necessary for all cells to survive and thrive in diverse environments. Key to these responses are the MAPK-mediated signaling pathways, intracellular communication routes that sense stimuli at the cell surface, and are ubiquitous in all eukaryotic organisms. In the case of fungi, MAPKs mediate essential processes, such as adaptation to environmental stresses, morphology regulation, or developmental processes. First studied in the early nineties in Saccharomyces cerevisiae, the fungal cell wall integrity (CWI) pathway has proven to be a central MAPK-mediated signaling cascade conserved in the fungal kingdom. Cells need to sense cell wall-perturbing conditions and mount the appropriate salvage response. Understanding this CWI pathway-mediated compensatory mechanism is key for the development of cell wall-targeted antifungal therapies. Moreover, its functional roles go beyond the maintenance of this essential structure, reaching many other physiological aspects that have major implications in development or virulence.In this Special Issue, expert researchers in this relevant subject have contributed with seven reviews and eleven original articles to advance our understanding of the CWI pathway by covering different structural, regulatory, and functional aspects in distinct yeasts and filamentous fungi
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  • 48
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576879 , 9783036576862
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (276 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. Each of the subtypes is divided into a number of families. For instance, P2 receptors are divided into P2X and P2Y receptors according to the mechanism by which their effect is realized: P2Y are G-protein-coupled receptors, while P2X receptors are ligand-operated ion channels. P2X receptors are important molecular therapeutic targets, the malfunctioning of which leads to severe complications in the physiology of humans and animals and causes dangerous diseases. The search for compounds that can modulate the function of purinergic receptors can lead to the creation of new drugs that are effective in central and peripheral nervous system and immune system disease treatment, including neuroinflammation, hypoxia/ischemia, epilepsy and neuropathic pain. In this Special Issue, we wish to offer a platform for high-quality publications on the latest advances in the identification of P2X/Y- and P1-receptor blockers, functions and regulation by them; the characterization of these receptor signaling networks and crosstalk; mechanisms underlying the role of purinoceptors in neurodegenerative illnesses as well as chronic neuronal changes following acute noxious damage and therapeutic opportunities associated with regulation of purinergic receptor activity
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  • 49
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562674 , 9783036562681
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (176 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: Cystic Fibrosis is an inherited disease that starts in utero. It is caused by a defective protein called the CF transmembrane conductance regulator (CFTR) and while the effects are seen throughout the body, changes in the lungs, gastrointestinal tract, pancreas and liver primarily impact nutritional status. Survival and pulmonary function have been linked to nutritional status. Malnutrition and growth failure were historically the hallmark of disease. Patients with pancreatic insufficiency require pancreatic enzyme replacement therapy and fat-soluble vitamin supplements. With improvements in many areas including newborn screening, nutrition supplements, pancreatic enzymes, CFTR modulator drugs, inhaled antibiotics and mucolytics, life expectancy has increased. In this issue, we will review the latest information in children and adults regarding important factors that play a role in optimizing nutrition status, including body composition, the gut microbiome, food security, pancreatic enzyme replacement therapy, growth and bone health, and micronutrient abnormalities. Pediatric and adult providers both need to be aware of the nuances of care as more patients with CF become adults. Optimizing nutritional status, anticipating and preventing the complications of CF will result in best management practice
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  • 50
    ISBN: 9783036568300 , 9783036568317
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (306 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Fruit- and vegetable-based products (F&Vs) have been conventionally processed using thermal techniques such as pasteurization, scalding, and/and drying, ensuring microbial safety and/or enzyme deactivation. Although thermal treatments are the most cost-effective tools, they could also reduce bioactive compounds, nutrients, and even sensory attributes. Nowadays, non-thermal food-processing technologies such as UV light and high-pressure processing have been proposed to develop food products with extended shelf life and preserved/encouraged bioactive compounds, while preserving the sensory properties. This reprint addresses the existing knowledge gaps of novel thermal and non-thermal techniques in the production of F&Vs and their derivatives. This reprint focuses on the effect of thermal and non-thermal treatments (light stresses, high hydrostatic pressure, pulse electric fields, oscillating magnetic fields, cold plasma, ultrasound, drying, etc.) on shelf-life, key bioactive compound changes (antioxidants, nutraceuticals, flavonoids, and non-flavonoids), enzymatic antioxidant systems, and non-enzymatic antioxidant systems of fruit- and vegetable-based products. Apart from an editorial written by the guest editors, the Special Issue consists of 13 papers that cover a range of subjects: thermal and non-thermal treatments on whole fruits (n = 4); thermal and non-thermal treatments on fruit and vegetable byproducts (n = 3); and, thermal and non-thermal treatments on fruit-based beverages and purées (n = 6)
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  • 51
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569017 , 9783036569000
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (184 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: The main difficulty of radiotherapy is to destroy cancer cells without depletion of healthy tissue. Stem cells and cancers are tightly interrelated. On one hand, radiosensitivity/radioressistance of cancer stem cells affects the radiocurability of tumors. On the other hand, radiosensitivity is responsible for the stem cell depletion of organs at risk exposed to irradiation. Efficient solide cancer destruction is limited by the preservation of organ homeostasis. For this reason, targeted irradiation is an effective cancer therapy, but damage inflicted to normal tissues surrounding the tumor may cause severe complications. The consequences of stem cell depletion of healthy tissue irradiated are acute and chronic radiation diseases. Research on the radiosensitivity of cancer stem cells and adult stem cells associated with tissue regeneration medicine will bring forth the solution for optimal radiocurability associated with long-term patients’ quality of life
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  • 52
    ISBN: 9783036576770 , 9783036576763
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (258 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Botany & plant sciences
    Kurzfassung: Taxonomy, floristic studies, biosystematics, classical taxonomy, and modern taxonomic advances; phylogenomics, phylogenetics, and biogeography, including phylogeography; and the description of well-documented new taxonomic taxa, monographs, and taxonomic revisions. It incorporates data from classical morphology (including both macro and micro morphology), molecular study, anatomy and ecology, distribution, molecular evolution, evolutionary development, population biology, conservation biology, evolutionary ecology, paleobiology, and related methods and theories in recent development in systematics and floristic studies
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  • 53
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575193 , 9783036575186
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (212 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Forestry & related industries
    Kurzfassung: Air pollution and the changing climate are some of the greatest threats to the health and functioning of forest ecosystems, strongly jeopardizing their ecological and economic functions as well as services. The impact of increasing temperatures and extreme weather events (droughts, storms, temperature and precipitation extremes) on the vitality of forest trees is often difficult to separate from the impact of pollution, such as nitrogen deposition and tropospheric ozone, as they can exhibit synergistic effects. The use of indicators is elementary in modern forest ecophysiological research, as they help us to disentangle complex interactions between trees and various stress-inducing factors as well as better estimate the level of damage to trees and forest ecosystems.Eleven papers are included in this Special Issue, with wide-ranging topics from various disciplines but centered around tree responses to environmental stress. The task of this Special Issue is twofold: one, to remind us that a better understanding of the physiological processes influencing tree vitality under the changing climate and air pollution pressures requires considerable research efforts and constant advancements in research methods and approaches; two, to highlight the fact that the environmental pressures instigating the use of tree stress response indicators are more present than ever, and will likely continue to affect tree vitality in the foreseeable future
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  • 54
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576978 , 9783036576961
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (272 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: The demand for plant proteins continues to increase due to the growing global population, rising protein deficiency, and their versatile environmental, functional, nutritional, and health benefits. Plant proteins represent a more sustainable source to (partially) supplement costly animal-based foods. Many factors can influence protein functionality and application, such as protein sources, production methods, molecular structures, chemical properties, food formulations and environment, and food processing techniques. The potential applications of plant proteins are diverse. This reprint covers diverse topics related to the characterization, chemistry, interaction, processing, modification, functionality, and/or application of various plant proteins in relation to human food
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  • 55
    ISBN: 9780367705565 , 9780367702977
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (45 p.)
    Schlagwort(e): Complementary medicine ; Botany & plant sciences ; Biology, life sciences ; Forestry & silviculture: practice & techniques
    Kurzfassung: This current chapter reports an initially singular case of a PD patient in Germany who could not be treated with conventional PD medication and whose quality of life had deteriorated dramatically after diagnosis, including long episodes of psychoses. Following therapy with an Ayurvedic (botanical) preparation from the beans of Mucuna pruriens (MP) – the patient´s fate was improved substantially at the time. This compelling, and – rather by fortune – well-documented case was pivotal to spreading the experience with MP within the European network of PD patients, mostly by word of mouth. The PD patient community and neurologists were supported by available online information around the medicinal plant, MP, and the bean´s active components, as well as an initial clinical study followed by a second one in 2004. Based on this first evidence, some neurologists were willing to support their patients with MP-based complementary therapy. As far as the authors are aware, from approximately 1997 until to date such cases were treated predominantly in Germany, Switzerland, Austria and The Netherlands. Clinical experience is mainly based on the feedback from patients and volunteers pushing to understand the added value of MP and prompting the availability of a safe and effective natural medicinal product that can be prescribed to PD patients. Their findings constitute the basis of this chapter
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  • 56
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036572277 , 9783036572260
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (536 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This Special Issue contains 28 papers covering a wide range of topics related to plant genomics and genetics. The papers utilize a variety of genomic tools and techniques to explore topics such as identification of quantitative trait loci associated with flax seed yield and oil quality, mucilage and hull content in flax seeds, and genomic prediction for pasmo resistance in flax. Other papers focus on the identification and characterization of specific genes, such as the EXO70 gene family in wheat and related species, hydroxycinnamoyl transferase in tea plants, and the WRKY transcription factor GmWRKY12 in soybeans. Several papers examine gene expression and regulation in response to abiotic stress, such as drought and salt tolerance in moso bamboo, and the response to chilling in bell peppers. Other topics include genetic diversity analysis of crested wheatgrass, genome-wide analysis of chitin-binding protein gene family in peppers, and genome-wide bioinformatics analysis of MAPK gene family in kiwifruit. Overall, this Special Issue provides a comprehensive view of the current state of plant genomics research, showcasing the diversity of approaches and tools being used to better understand and improve crop plants
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  • 57
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574110 , 9783036574103
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (184 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: Environmental issues have attracted great attention with the pursuit of a high quality of life, and the effective removal of environmental pollutants is a great challenge today. This includes two topics: one is to remove the pollutants produced post-treatment, and the other is to synthesize chemicals by a green route, avoiding producing pollutants in the process.Catalytic technology is an effective way to solve environmental problems, which can facilitate the conversion of pollutants to nontoxic or even useful chemicals. Thus, this reprint focuses on resolving the environmental problems by a catalysis technology, including photocatalysis, thermocatalysis, and electrocatalysis. Research works relating to the catalytic removal of pollutants or the catalytic synthesis of chemicals by a green route are reported
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  • 58
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571546 , 9783036571553
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (160 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Animals & society
    Kurzfassung: Milk and meat products originating from small ruminants contain biologically active compounds, such as high-quality proteins, vitamins, minerals and fatty acids that have been proven to have beneficial effects on human nutrition, metabolism and health. However, the raising consumer demands for safe animal products of high nutritional value has reshaped the direction of livestock production and food industry. Currently, research efforts are focused on the development of niche functional products that fortify human health and are in harmony with the concept of sustainable production, green economy, environmental protection, and proper health and welfare status of farm animals. Innovative feeding strategies are therefore evaluated that could promote ruminal function, enhance animal health and welfare status, increase production yield, improve quality of milk and meat products and prolong their shelf life by minimizing environmental burden and production costs
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  • 59
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561196 , 9783036561202
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (188 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: The prevalence of dietary supplement is increased in the world. The primary purpose of dietary supplements is the provide nutrients, such as vitamin and mineral, to maintain health. However, the functional ingredients in food, especially polyphenols, have attracted attention in recent decades, and these ingredients have beneficial effects on human health. On the other hand, a lot of ingredients with poor evidence as to their effects have also been marketed as dietary supplements, and adverse events associated with dietary supplement use have been reported. It is important to choose dietary supplements whose efficacy and safety for our health have been studied
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  • 60
    ISBN: 9783036571805 , 9783036571812
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (42 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This book focuses on advanced research topics on human lactation, such as breastfeeding experiences, milk composition and production, COVID-19 and human milk, food allergens in human milk, the human milk microbiome, and the impacts of human milk on infant growth and development. The symposium proceedings aim to add diversity, passion, and innovation to lactation research and have a positive impact on mothers, infants, and communities worldwide, showcasing integrative mother/infant-centered research
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  • 61
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036572611 , 9783036572604
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (198 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: We are facing a complicated public health issue in the form of global drug shortages, including antibiotics. Synthetic biology empowers the next generation of antibiotics development, bringing us into a new era
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  • 62
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036581026 , 9783036581033
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (224 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: Obesity represents the most prevalent metabolic disease in the world, posing a significant public health threat. Obesity shortens life expectancy by increasing the risk of developing comorbidities such as type 2 diabetes or cardiovascular disease. A better understanding of the ethiopathology of excess adiposity represents the pillar on which to base the effective management of obesity. In this sense, this reprint expands our knowledge about the wide array of drivers that can facilitate or contribute to the development of obesity. Moreover, some of the latest progress made in lifestyle, pharmacological and surgical approaches in the treatment of obesity are summarised. Novel concepts regarding the different obesity phenotypes, the use of telemedicine for the treatment of overweight and obesity, or the use of personalised avatars in the management of obesity are also reviewed. This reprint will be of interest for specialists in Endocrinology and Nutrition, but also for any individual interested in health issues related to nutrition
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  • 63
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036583488 , 9783036583495
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (224 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint represents a collection of 12 scientific papers belonging to the Special Issue in International Journal of Molecular Sciences titled “Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition". Obesity is a serious global health problem with a high incidence of mortality and morbidity. Many drivers have been identified for its etiopathogenesis, such as excessive food intake, reduced physical activity and genetic predisposition. Adipose tissue is considered an endocrine organ producing multiple immune-modulatory proteins, known as adipokines with a pro-inflammatory or anti-inflammatory nature. An unbalanced production of adipokines with a pro-inflammatory role in adipose tissue induces low-grade systemic inflammation in obese patients, which predisposes them to insulin resistance, type II diabetes, cardiovascular disorders, and cancer. Nowadays, there has been a growing interest in finding novel target compounds, both natural and synthetic, with potential action against obesity. This reprint explores the mechanisms underlying the etiopathogenesis of obesity and related diseases and aims to identify new therapeutic strategy. In particular, the reprint focuses on the role of natural and synthetic compounds for the Management, Prevention and Treatment of Obesity. We thank all the authors for their contribution to the research topic of this reprint and all editorial staff for its valuable support
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  • 64
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036582627 , 9783036582634
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (392 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Ecological science, the Biosphere
    Kurzfassung: Chondrichthyes (sharks, skates, rays, and chimaeras) represent one of the oldest and most ecologically various vertebrate lineages. These predators occupy the top of aquatic food webs and play important functional roles in the control of coastal and oceanic ecosystem structure and function; however, nowadays, overfishing and habitat degradation are altering their populations, leading to a worrisome decline in these species worldwide because of their low resilience due to their K-selected life history strategy (e.g., slow growth, late attainment of sexual maturity, long life spans, and low fecundity). Moreover, data on the stock status of this important resource still remain poor or non-existent, which is due to a problematic taxonomy (e.g., misidentification issues). In these regards, collecting information about these species is essential to formulate conservation strategies to preserve this precious marine resource. In this Special Issue, we aimed to expand the knowledge about these important predators. We have collected data from several parts of the Atlantic and Pacific Oceans and the Mediterranean Sea. The main topics presented in this Special Issue are as follows: abundance and distribution of a single species or more, genetic information using different techniques, life histories (e.g., reproduction, age, and growth), demographic analyses, information about stock assessment, aggregative behaviors, and prey discrimination
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  • 65
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573984 , 9783036573991
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (178 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: Light is an essential factor for the growth and quality of horticultural plants and its effects depend upon parameters such as duration, intensity and quality. It is an energy source for photosynthesis as well as a signal triggering plant photomorphogenesis and physiological, biochemical and molecular responses. However, solar light strongly differs between winter and summer conditions, with excess light in open field cultivations imposing severe stress on plants, especially during summer months, while supplementary light sources are implemented in greenhouse crop production to complement natural light when it is insufficient. On the other hand, artificial lighting is used as the sole lighting source in plant factories and nurseries (i.e., healing chambers, plant tissue culture). In order to enhance sustainability and profitability, light must be studied and efficiently applied within horticultural crop production. Novel technologies such as light-emitting diodes, new transparent greenhouse covering materials, photoselective nettings, growth chambers and plant factories showcase the critical role of light interacting with plants from the level of seed germination to growth rate, product quality and postharvest storage. This Special Issue focuses on recent findings in horticultural crops with regard to light characteristics (i.e., quality, quantity etc.) presented as research papers, short communications and review articles
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  • 66
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036581705 , 9783036581712
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (224 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This Special Issue contains 12 articles evidencing the state of the art of research on the evolution and genetics of reptiles. One of the main lines of research concerns the advancements in phylogenetic studies based on the more recent molecular methods and the developments in whole genome sequencing. Among the papers, topics related to the analysis of genome composition with special reference to the presence and evolution of repetitive DNA and the control of gene activity are of interest. Examples of the different roles played by chromosome variability in various evolutionary models are reported. Some of the papers regard certain peculiarities of reptiles, such as meiotic mechanisms in parthenogenetic species and the transition between genetic and environmental sex determination. Besides studies on chromosomes and the nuclear genome, two papers also investigate mitochondrial genome evolution. Particularly promising for future studies is the potentiality gained by the results obtained so far from research into the evolution and genetics of reptiles that has also been used for an intriguing tentative motion to reconstruct dinosaurs’ karyotypes. The papers from this Special Issue highlight that reptiles are a good model for studying the genetic and molecular basis of certain key moments in vertebrate evolution
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  • 67
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036580104 , 9783036580111
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (332 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: The externalization of animals’ genetic potential is determined by a number of external factors, of which feeding plays a major role. Animals’ nourishment is one of the most important levers to ensure the efficiency of animal production due to both the high share of feed costs in the total cost of products and the influence this has on the growth, reproduction, and health of animals as well as the quality of products obtained from these. This field is one of the most dynamic in the field of husbandry sciences due to the takeover and permanent use of numerous results obtained from research on energy metabolism and nutrients related to the composition of feed and its influence on animal products. This is also due to the great advances in genetics, which create new types of animals with increasing productive potential, but also with different food requirements. This Special Issue collated innovative papers on animal nutrition, physiology, chemistry, biochemistry, genetics, reproduction, and breeding technologies. The articles covered a wide range of topics related to feed quality, the influence of food on the production level, the quality of production, and also on animals’ health
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  • 68
    ISBN: 9781800644106 , 9781800644113
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Research methods: general ; Research & information: general ; Research & development management ; Data capture & analysis ; Data mining ; Biology, life sciences ; Medical bioinformatics
    Kurzfassung: This book is an introduction to the language of systems biology, which is spoken among many disciplines, from biology to engineering. Authors Thomas Sauter and Marco Albrecht draw on a multidisciplinary background and evidence-based learning to facilitate the understanding of biochemical networks, metabolic modeling and system dynamics. Their pedagogic approach briefly highlights core ideas of concepts in a broader interdisciplinary framework to guide a more effective deep dive thereafter. The learning journey starts with the purity of mathematical concepts, reveals its power to connect biological entities in structure and time, and finally introduces physics concepts to tightly align abstraction with reality. This workbook is all about self-paced learning, supports the flipped-classroom concept, and kick-starts with scientific evidence on studying. Each chapter comes with links to external YouTube videos, learning checklists, and Integrated real-world examples to gain confidence in thinking across scientific perspectives. The result is an integrated approach that opens a line of communication between theory and application, enabling readers to actively learn as they read. This overview of capturing and analyzing the behavior of biological systems will interest adherers of systems biology and network analysis, as well as related fields such as bioinformatics, biology, cybernetics, and data science
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  • 69
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    Nijmegen : Radboud University Press
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (450 p.)
    Schlagwort(e): Biology, life sciences ; Cytology ; Genetics (non-medical) ; Molecular biology ; Music recording & reproduction
    Kurzfassung: Reproduction is an important central topic in biology. Reproduction genetics are at the heart of some of life’s most basic questions such as: where do we come from, what are we and where are we going? Reproduction genetics connects current generations with past and future ones, and is intimately connected with fertility and infertility. The cellular lineage instrumental in the passage of life is called the germline while the mature functional products are the gametes. These form the main theme of this book. This book bridges the gap between existing textbooks and society by describing the germline as a passage in time. This book includes high quality illustrations, a complete glossary and references for each chapter, with the most prominent research highlighted. The interactions between the science of reproduction genetics and society are addressed. The text also includes personal experiences of the author from a 40-year career in the field. The book aims to combine knowledge and insight for an audience with some knowledge of the intertwined sciences of genetics and reproduction. The ‘knowledge landscape’ has been organised into 19 chapters. The book is aimed at those dealing with these subjects professionally, in education and elsewhere. It also has a lot to offer the educated layman thanks to the excellent illustrations and up-to-date glossary of scientific terms
    Anmerkung: Dutch , Flemish
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  • 70
    ISBN: 9783036562759 , 9783036562766
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (224 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Ecological science, the Biosphere
    Kurzfassung: This reprint focuses on the theoretical principles and practical adoption of remote sensing approaches and datasets in understanding the nexus between urbanization, natural landscapes, urban micro-climate, climate change and Urban Heat Islands. Urbanization, characterized by natural landscape transformation, influences thermodynamics, surface energy and micro- and macro climate perturbations. These changes result in environmental deterioration that in turn adversely affects bio-physical processes and quality of urban life. A major consequence of urbanization is the Urban Heat Island (UHI). It is anticipated that the increased UHIs, in concert with the increasing anthropogenic activities, will further increase the vulnerability of urban landscapes to climate-related disasters such as floods and heatwaves. Recent advances in optical and thermal remotely sensed datasets offer great potential in understanding the relationship between urban bio-physical characteristics and UHIs. Hence, this reprint provides a basis for understanding urban ecological and thermal patterns, which is critical for the management of urban physical, ecological and social processes within a remotely sensed data framework. This reprint should be of interest to both specialists and generalists interested in, among other fields, urban planning, ecological conservation, the urban micro-climate, and climate change
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  • 71
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036560328 , 9783036560311
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: Antibiotic resistance represents one of the most important challenges in the world and involves humans, animals and the environment.For this reason, it is increasingly important to focus our attention on the present scenarios and the future prospects relating to this problem. The One Health approach helps us and can provide the tools to consider the problem from different points of view, also providing alternative solutions to the use of the antibiotic itself
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  • 72
    ISBN: 9783036563015 , 9783036563022
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (196 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Greenhouse cultivation provides an artificially controlled environment for the year-round production of vegetables, and has played an increasingly important role in agriculture production systems in recent decades. Recent works have shown that improving greenhouse conditions can promote the growth of vegetables and enhance the uptake of nutrients, leading to better vegetable quality. Meanwhile, greenhouse conditions not only directly influence soil nutrient cycling processes and properties, but also indirectly affect them by regulating vegetable root growth and plant–soil interactions. This Special Issue features twelve original research articles that deal with the effects of novel greenhouse practices and strategies on the yield and quality of horticulture crops, as well as greenhouse soil properties. Among these publications, three studied the effects of fertilizers, including organic and macro- and micro-nutrient fertilizers, on the growth and nutrient uptake of vegetables. Two articles described the effects of water and nutrient supply using irrigation or hydroponic supplying systems on the yield and quality of vegetables. Four articles investigated the effects of environmental conditions (mainly light and temperature) on the growth and quality of vegetables. In terms of degenerated greenhouse soil, three articles showed how reductive soil disinfestation decreased soil salinity, improved soil quality, and inactivated soil-borne pathogens
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  • 73
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036561448 , 9783036561431
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (480 p.)
    Schlagwort(e): Biology, life sciences
    Kurzfassung: Fungal natural products have made important contributions to the history of human civilization. Mr. Liu Jikai has had a significant influence on the field of chemistry in fungal natural products, leading a large number of Chinese scholars engaged in related research. We would like to take this opportunity to thank Mr. Liu Jikai for his efforts on fungal natural products chemistry and hope that all colleagues will make great progress for the future
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  • 74
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036562391 , 9783036562407
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (268 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Animals & society
    Kurzfassung: This reprint focuses on applied research on growth traits, fat reserves, fatty acid profiles and enriched diets and their effects on reproduction, health status and welfare. The studies contained in the volume have been carried out in both monogastric organisms and ruminants, fish, broilers or pigeons. Fundamental studies with rats or mice are also presented. The reader will find novel research about the effects of the degree of fatness and muscularity determined by ultrasound method on sows´ reproductive performance, genetic studies on fatty acid profiles and growth traits in rabbits and Gilthead Seabream; nutritional studies addressing diets enriched with bee pollen in rats, postbiotics in male rabbits, concentrate and bypass supplementations in buffaloes; and interesting studies on the welfare assessment of meat sheep, rabbits, racing pigeons, broilers, alpacas and llamas using body condition measurements
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  • 75
    ISBN: 9783036559759 , 9783036559766
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (172 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Genetics (non-medical)
    Kurzfassung: In this Special Issue of Genes entitled “Genetic Conditions Affecting the Skeleton: Congenital, Idiopathic Scoliosis and Arthrogryposis”, evidence is presented that suggests that congenital, idiopathic scoliosis, and arthrogryposis share similar overlapping, but also distinct, etiopathogenic mechanisms, including connective tissue and neuromuscular mechanisms. Congenital scoliosis (CS) is defined by the presence of an abnormal spinal curvature, due to an underlying vertebral bony malformation (VM). Idiopathic scoliosis (IS) is defined by the presence of an abnormal structural spinal curvature of ≥10 degrees in the sagittal plane, in the absence of an underlying VM. Arthrogryposis is defined by the presence of congenital contractures in two or more joints of the appendicular skeleton. All three conditions have complex genetic causes. This Special Issue highlights the complex nature of these conditions and current concepts in our approach to better understand their genetics
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  • 76
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565651 , 9783036565644
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (220 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Biochemistry
    Kurzfassung: This Special Issue addresses both new scientific insights and technological advances of gluten-free product development exploring alternative ingredients for the development of gluten-free products aiming to mimic the unique viscoelastic properties of gluten as a gas retention ingredient during fermentation, water binding and enabler of starch gelatinization on baking, and a bread flavor enhancer via gluten-related proteases
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  • 77
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036565248 , 9783036565231
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (220 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: The emergence of antibiotic-resistant pathogens currently represents a serious threat to public health and the economy. Due to antibiotic treatments in humans and veterinary medicine, prophylactic use and environmental contamination, bacteria are today more frequently exposed to unnatural doses of antibiotics and their selective effect.Antibiotic resistance can be encoded on chromosomes, plasmids, or other mobile genetic elements in bacteria. It may also result from mutations that lead to changes in the affinity of antibiotics for their targets or in the ability of antibiotics to act on bacterial growth or death. Exposure of bacteria, bacterial populations, and microbial communities to antibiotics at different concentrations shapes their genomic dynamics, as does the mobilisation and spread of resistance determinants. It is, therefore, essential to understand the dynamics and mobilisation of genes encoding antibiotic resistance, in human, animal, plant, and environmental microbiomes, through genomic and metagenomic approaches and bioinformatics analyses.This Special Issue gathers research publications on the horizontal transfer of antibiotic-resistance genes, their dissemination and epidemiology, their association with bacterial virulence, between bacterial genotypes and their phenotypes, and other related research topics
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  • 78
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569499 , 9783036569482
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (374 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint presents the published papers of a Special Issue titled Antioxidant Activity of Essential Oils, of the journal Antioxidants, MDPI. Obviously, essential oils are a point of huge interest, due to them being rich in bioactive substances (with their recognised antioxidant, immunomodulatory, antibacterial, antiviral, etc., effects) and are also used extensively in the beauty/cosmetic industry, food products, etc. Considering the global trend of "return to nature", both in eating habits/nutrition, and in the adjuvant therapies (implying essential oils) addressed in the case of numerous diseases, and taking into account the interest of the authors who submitted their papers, the current topic can be considered to be of great interest and with increased and promising potential for future research
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  • 79
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568485 , 9783036568492
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (190 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: Dietary patterns are evolving, and we are increasingly aware of the contribution of food and food systems to community and planetary health. To be responsive to these changes and to promote dietary patterns that enhance the health and wellbeing of populations and protect against climate change, nutrition professionals and researchers need to monitor evolving dietary patterns and trial comprehensive, multiaction solutions. Countries are pushing back on corporate and climate change disruptions to food systems and are looking for ways to strengthen community involvement in food systems, so that healthy and environmentally friendly food choices are easier to make. To achieve this, policymakers need access to the latest evidence on evolving dietary patterns and on effective solutions, and this Special Issue on Progress in Community Nutrition: Dietary Patterns and Planetary Health provides some of this evidence
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  • 80
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036567860 , 9783036567877
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (126 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This Special Issue aims to bring together the various aspects of plant cell tissue and organ culture with a special emphasis on the production of phytochemical compounds, considered therapeutically valuable for their antioxidant, antiviral, antibacterial, and anti-inflammatory properties. Secondary metabolites play a key role in the diverse defense mechanisms of the plant organism in response to environmental stimuli, such as climatic fluctuations, pathogenic organisms, predatory herbivores, and competing plants. Therefore, by providing the opportunity for controlled modifications of environmental conditions, in vitro culture is an easy-to-manage experimental system that can be utilized as a source of secondary metabolites for industrial applications, as well as for food, cosmetic, and pharmaceutical purposes. This Special Issue will highlight the modern use of different plant cell tissue and organ culture approaches for successfully producing plant secondary metabolites, particularly those with high economic value
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  • 81
    ISBN: 9783036571300 , 9783036571317
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (214 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: A major task for health professionals and health systems is effectively preventing and treating cardiovascular and metabolic diseases. This reprint offers an updated set of experimental and clinical information on the usefulness of nutraceutical products for the management of cardiometabolic diseases, which range from obesity and diabetes mellitus and their complications to hypercholesterolemia. The nutraceutical option may be used according the “beyond diet, before drug” strategy and is particularly relevant in the cardiometabolic field. The chapters of this reprint offer a deep insight into relevant issues in this nutraceutical field, such as experimental research for the preclinical identification of interesting compounds of natural origin, quality of nutraceutical products and their efficacy and safety, regulatory aspects, and the quality of evidence-based medicine
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  • 82
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036569826 , 9783036569833
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (112 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This reprint aims to provide a wide range of viable alternative designs that utilize valuable compounds from spicy and aromatic plants. Spices and aromatic plants have been used for thousands of years to flavor food, but they can also be used for healing purposes. Until a few decades ago, however, this was performed with little knowledge of their actual properties. The attitude toward these plants has changed, and the need for knowledge has increased. The studies are oriented towards an in-depth analysis of the valuable compounds in these plants in order to be used in the food, pharmaceutical, cosmetic, and agricultural industries
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  • 83
    ISBN: 9783036553955 , 9783036553962
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (278 p.)
    Schlagwort(e): Research & information: general ; Chemistry ; Biology, life sciences ; Development economics & emerging economies
    Kurzfassung: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies
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  • 84
    Online-Ressource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573960 , 9783036573977
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (374 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Due to increasing concern about the use of pesticides and its potential side effects, this book considers the development and application of alternative, environmental-friendly, plant protection methods for the control of weeds, disease, and pests (predators, parasitoids, competitors, plant-plant interactions, microelements, biopesticides). Some of the main advantages of the measures presented in papers are the absence of toxicity to humans and vertebrates, beneficial organisms, and the environment, as well as the absence of pest resistance. In order to provide sustainable and eco-friendly food production, those are important subjects, both in conventional, organic and integrated agricultural farming. Through reviews and original research articles, this reprint covers all aspects of alternative measures in plant protection
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  • 85
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576138 , 9783036576121
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (214 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: This reprint aims to present research on Socio-Economic Functions Across Sustainable Farming Systems, specifically on environmental conservation agriculture/climate-smart agriculture, which boosts nature-positive production, raises the welfare of producers; agricultural biotechnology, which contributes to economic and environmental sustainability; community-based extension and marketing of farm produce, which ensures the livelihood of producers and access to safe and nutritious food; and building a society resilient to all kinds of crises and hazards/disasters.This reprint reveals: 1) Drivers and dynamics of environmental conservation agriculture, the sustainable farming systems in Japan to address climate change, biodiversity conservation, sustainable production, welfare of producers and leveraging their participation in Globally Important Agricultural Heritage Systems. 2) Biotech crops in the Philippines can coexist with the practice of climate resilient environmental conservation agriculture. 3) Community-based extension services, such as farmer field school, disaster management practices, such as flood adaptation strategy, and marketing strategy of farm products enhance the welfare of rural population in Bangladesh.4) Identification of socio-economic characteristics associated with farming practices, food safety, food security and their constraints in South Africa and Senegal. 5) Benefit of financing agricultural cooperatives to enhance sustainable production in Romania
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  • 86
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    Oakland : University of California Press
    ISBN: 9780520391192
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (344 p.)
    Schlagwort(e): Biology, life sciences
    Kurzfassung: This book investigates rabbinic treatises relating to animals, humans, and other life-forms. Through an original analysis of creaturely generation and species classification by late ancient Palestinian rabbis and other thinkers in the Roman Empire, Rafael Rachel Neis shows how rabbis blurred the lines between humans and other beings, even as they were intent on classifying creatures and tracing the contours of what it means to be human. Recognizing that life proliferates by mechanisms beyond sexual copulation between two heterosexual “male” and “female” individuals of the same species, the rabbis proposed intricate alternatives. In parsing a variety of creatures, they considered overlaps and resemblances across seemingly distinct species, upsetting in turn unmitigated claims of human distinctiveness. When a Human Gives Birth to a Raven enters conversations in animal studies, queer theory, trans theory, and feminist science studies to provincialize sacrosanct ideals of reproduction in favor of a broader range that spans generation, kinship, and species. The book thereby offers powerful historical alternatives to the paradigms associated with so-called traditional ideas. “An original and groundbreaking study, Neis’s analyses open a window to a much more complex and surprising intellectual world than the rabbis usually get credit for. This book is provocative, thoughtful, and timely.” — MIRA BALBERG, Professor of History and Endowed Chair in Ancient Jewish Civilization, University of California, San Diego “A trailblazing work that introduces a new, sophisticated discourse in the study of rabbinic literature. Neis is at home in the classical rabbinic texts, with their philological complexity and immense width, encompassing half a millennium and diverse historical circumstances.” — GALIT HASAN-ROKEM, Professor Emerita of Hebrew Literature and Folklore Studies, Hebrew University of Jerusalem"
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  • 87
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    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577371 , 9783036577364
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (308 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extracellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity. This control involves multiple temporal and functional steps as well as innumerable molecules including transcription factors, cofactors, and chromatin regulators. It is well known that many human disorders are characterized by global transcriptional dysregulation because most of the signaling pathways ultimately target transcription machinery. Indeed, many syndromes and genetic and complex diseases—cancer, autoimmunity, neurological and developmental disorders, and metabolic and cardiovascular diseases—can be caused by mutations/alterations in regulatory sequences, transcription factors, splicing regulators, cofactors, chromatin regulators, ncRNAs, and other components of transcription apparatus. It is worth noting that advances in our understanding of molecules and mechanisms involved in the transcriptional circuitry and apparatus lead to new insights into the pathogenetic mechanisms of various human diseases and disorders. Thus, this Special Issue is focused on molecular genetics and genomics studies exploring the effects of transcriptional misregulation on human diseases
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  • 88
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036576855 , 9783036576848
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (152 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: The purpose of this reprint based on the Special issue "Molecules in Diabetes Melitus, Dyslipidemia and Cardiovascular Disease”, IJMS journal, MDPI, is to present the impact in clinical practice as well as in medical research of novel molecules that have been introduced in the treatment of diabetes mellitus, dyslipidemia, and cardiovascular disease
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  • 89
    ISBN: 9783036576190 , 9783036576183
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (204 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: The present reprint aimed to present original research articles and reviews concerning the following:Access: affordability, allocation, and preference of food;Availability: the production, distribution, and exchange of food;Circularity in food systems at local, regional, or global levels;The development, impact, and ethics of novel and data-driven technologies in food systems;Food security and policy, governance, institutions, and trade;Influencing food consumption and demand regarding the food environment;The stability and dynamics of food security aspects;Sustainable food systems and agro-ecological food production;Utilization: the nutritional value, social value, and safety of food
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  • 90
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573939 , 9783036573922
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (254 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: The manuscripts published in this reprint provide new insights into the hypothalamic neuronal and non-neuronal pathways involved in the pathophysiology and development of obesity and related diseases such as diabetes. Via four original papers, six review manuscripts, and one perspective, this reprint will substantially contribute to the identification of novel therapeutic targets in the hypothalamus and novel approaches to combatting the progression of human obesity
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  • 91
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573618 , 9783036573601
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (150 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: This Special Issue, "Scientific Papers by Developmental Biologists in Japan", represents a collection of high-quality review articles, research articles, and communications on the development of multicellular organisms at the molecule, cell, tissue, organ, and whole-organism level, which were written and submitted by developmental biologists working in Japan
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  • 92
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036572185 , 9783036572192
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (194 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Technology, engineering, agriculture
    Kurzfassung: Abiotic stress includes not only single adversities, i.e., drought, salt, temperature, and elevated CO2, but also complex stresses, i.e., saline and alkali soil, and karst environment. Abiotic stresses strongly affect many aspects of a plant’s substance and energy metabolism. Meanwhile, abiotic stress not only affects the physiological processes of photosynthesis, water metabolism, and inorganic nutrient absorption, but it also influences the electrophysiology and other physical parameters of plants. Plant physiological information, especially online physiological information, helps us to understand the plant’s adaptive mechanism and take the effective measures to improve the production of horticultural plants. This Special Issue contains a collection of 11 important research works, which deepen the connotation and expand the denotation of plant physiology under abiotic stress. These works will provide a theoretical basis for the production of horticultural crops under single stresses, such as drought and salt stress, or under complex stresses, such as saline and alkali and karst environments. Readers from all over the globe are expected to greatly benefit from this Special Issue collection both in terms of their own work and to improve the productivity of horticultural crops under complex abiotic stresses. In the future, we hope that the field of plant (horticultural crop) physiology under abiotic stresses flourishes in terms of academic research and publications
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  • 93
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573038 , 9783036573021
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (366 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: "Molecules at Play in Cancer" is a collection of 24 research articles on recent findings about some important molecules responsible for either cancer development and proliferation, or anti-cancer therapy. It covers a wide range of tissues and organs affected by cancer: adrenal glands, blood, breasts, muscles, ovaries, prostate, stomach, and testicles
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  • 94
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036568508 , 9783036568515
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (208 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: This Special Issue collects research on and applications of the relationship between food, nutrition, and databases. The development of databases of nutrients, bioactive compounds, and metabolites are key tools for human health and public nutrition and represent resources for a wide range of applications in food, pharmaceutical, nutraceutical, epidemiology, and medicinal areas. The current research trends are highlighted
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  • 95
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036571324 , 9783036571331
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (272 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: The effects of nutrition on chronic conditions, such as diabetes, obesity, heart disease, and stroke, continue to generate interest among researchers. This is because diet is a modifiable risk factor. The composition of diet, including the proportions and types of macronutrients and micronutrients, is a major contributor to chronic diseases. The beneficial effects of nutritional interventions on chronic conditions have been well documented, although differences remain among researchers concerning their overall impact. The evaluations of the role of nutrition in chronic conditions draw on diet’s effects on body weight, body composition, glycemic, and insulin excursions, and vascular remodeling. The effect of diet in modulating gut microbiota dysbiosis is also an evolving area of research. This reprint, entitled “Nutrition in Chronic Conditions”, aims to examine the effect of nutrition in the development, care, and management of chronic conditions. This reprint includes 11 original studies conducted in high- and middle-income countries, 3 systematic reviews with meta-analysis, and 3 literature reviews. The topics covered in the reprint include: the effects of diet on (1) insulin and glucose metabolism; (2) gut health; (3) brain and cognitive impairment; (4) infections, chronic conditions, malnutrition, and all-cause mortality; (5) obesity and dietary variables in post-menopausal women; (6) non-alcoholic fatty liver disease in mice, specifically with the consumption of coffee; and (7) chronic conditions and COVID-19 infection
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  • 96
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036573847 , 9783036573854
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (172 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences
    Kurzfassung: Pathogenic fungi and mycotoxins threaten plant and animal health and cause economic losses. This book focuses on the recent research progress into pathogenic fungi and mycotoxins in China. The molecular mechanisms of mycotoxin biosynthesis and pathogenic fungi growth and development are reported from the perspectives of transcription regulation, histone modification and enzymes, providing a theoretical basis for discovering new control targets. This Special Issue not only includes a review about the microbial degradation of mycotoxins, but also discusses several new chemical and biological methods which inhibit the biosynthesis of mycotoxin. Special attention is also given to the effect of nutrition on the production of mycotoxins. Some papers have also been collected about detection assays and the risk assessments of mycotoxins. The fundamental and applied research into mycotoxins is not only of particular interest but is also important for reducing economic losses
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  • 97
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    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036581866 , 9783036581873
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (510 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Fisheries & related industries
    Kurzfassung: Robust stress from the external environment does not only induce severe oxidative stress for aquatic animals, but also restricts the health and sustainable development of aquaculture. Oxidative stress is ubiquitous in aquatic animals, and excessive oxidative stress could induce cell and tissue damage. These phenomena manifest primarily as DNA hydroxylation, protein denaturation, lipid peroxidation and cell apoptosis. In general, endogenous and exogenous factors are the main elements that induce oxidative stress, including temperature, oxygen, life history, nutrition, food deprivation, industrial and agricultural pollutants. This Special Issue highlights and discusses the causes of oxidative stress, elucidates the underlying physiological mechanisms, and develops antioxidant resistance strategies that are of great importance for the development of aquaculture. More importantly, this Special Issue offers fresh perspectives on the expanding knowledge related to and research possibilities in the creation of antioxidant resistance in aquaculture
    Anmerkung: English
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  • 98
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036581828 , 9783036581835
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (162 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Food & society
    Kurzfassung: The purpose of this Special Issue, “The Role of Nutrition in Cardiometabolic Health: Experimental, Clinical, and Community-Based Evidence”, is to publish a focused, coherent, impactful, and well-cited volume on how nutrition influences diverse cardiometabolic risk factors. Cardiometabolic diseases such as coronary heart disease, stroke, type 2 diabetes mellitus, and obesity are the leading causes of death worldwide. In recent years, dietary habits have shifted all over the globe. At the same time, a constantly growing body of evidence demonstrates the role of caloric intake and dietary composition as determinants of cardiometabolic health. A suboptimal diet predisposes to a myriad of cardiometabolic risk factors such as impaired glucose metabolism, insulin resistance, dyslipidemia, and high blood pressure. The goal of this Special Issue is to provide rigorous evidence from novel experimental and observational studies that support the association between dietary factors and cardiometabolic risk and evaluate the diverse diet-related risk pathways
    Anmerkung: English
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  • 99
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036582382 , 9783036582399
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (220 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Microbiology (non-medical)
    Kurzfassung: In the last couple of years, the awareness of climate change and high pollution levels have raised our sense of ecological responsibility. Pharmaceutical industries play a major role in these issues; as such, alternatives must be found. New environmentally friendly approaches to deal with the growing concern associated with antimicrobial-resistant bacteria are also in great demand. The excessive consumption and misuse of these agents have accelerated the rise of such pathogens responsible for compromising global health—not only the health of humans, but also the health of all living systems. Considering that our natural resources are in great danger, finding green and less environmentally impactful alternatives for fighting these resistant microbials is imperative. From green chemistries, natural extracts and waste products, the sources of these alternate antimicrobial agents can be immense, and their implications are of great impact for future generations
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 100
    Online-Ressource
    Online-Ressource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575582 , 9783036575599
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (402 p.)
    Schlagwort(e): Research & information: general ; Biology, life sciences ; Botany & plant sciences
    Kurzfassung: This reprint of the Special Issue "Advances in Plant Taxonomy and Systematics", includes an Editorial and fifteen high-quality papers published between April 2022 and April 2023 by global researchers. This collection addresses scholars and students interested in current progresses in taxonomy and systematics, which are crucial for all plant applications
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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