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  • 1
    Online Resource
    Online Resource
    Chapter 4 Applications of Monte Carlo Simulation in Modelling of Biochemical Processes (2012)
    [Erscheinungsort nicht ermittelbar] : InTechOpen
    Details
    Language: English
    Pages: 1 Online-Ressource
    Keywords: Biochemistry
    Abstract: The biochemical models describing complex and dynamic metabolic systems are typically multi-parametric and non-linear, thus the identification of their parameters requires nonlinear regression analysis of the experimental data. The stochastic nature of the experimental samples poses the necessity to estimate not only the values fitting best to the model, but also the distribution of the parameters, and to test statistical hypotheses about the values of these parameters. In such situations the application of analytical models for parameter distributions is totally inappropriate because their assumptions are not applicable for intrinsically non-linear regressions. That is why, Monte Carlo simulations are a powerful tool to model biochemical processes
    Note: English
    URL: OAPEN Library: download the publication
    URL: OAPEN Library: description of the publication
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 2
    Online Resource
    Online Resource
    Fibrinolysis and Thrombolysis (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112655 , 9789535172031
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Haematology
    Abstract: This book familiarizes the reader with some recent trends in the theory and practice of thrombolysis. It covers the field of fibrinolysis from the standpoint of basic scientists and clinicians and delivers the state-of-the-art information on the biochemistry and pharmacology of fibrinolysis, as well as related novel methodological and diagnostic tools in the field. An introductory chapter summarizes the basic molecular mechanisms in fibrinolysis (plasminogen, its endogenous activators and their inhibitors, plasmin and its inhibitors). Recent developments in our understanding of fibrin formation are described in the context of its impact on fibrinolysis. The discussion of neutrophil extracellular traps in the modulation of fibrin assembly and the consequences regarding plasminogen activation and plasmin action addresses a novel aspect of fibrinolysis
    Note: English
    URL: kostenfrei
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    MPI Ethno. Forsch.
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