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  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (235)
  • Infectious & contagious diseases  (133)
  • Immunology  (102)
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  • 1
    ISBN: 9781803564982 , 9781803564975 , 9781803564999
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (120 p.)
    Serie: Infectious Diseases 28
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Taeniasis and Cysticercosis/Neurocysticercosis - Global Epidemiology, Pathogenesis, Diagnosis, and Management is a comprehensive and up-to-date overview of these two closely related parasitic diseases. The book covers all aspects of taeniasis and cysticercosis/neurocysticercosis, from epidemiology and pathogenesis to diagnosis and treatment. It also includes specific topics on the two Taenia species that infect humans, T. solium and T. saginata, and a third species, T. asiatica. This book is an essential resource for anyone wanting to learn more about taeniasis and cysticercosis/neurocysticercosis and how to prevent and control these diseases. It is written by leading experts in the field and includes the latest advances in epidemiology, diagnosis, treatment, and control. This volume is a useful resource for a wide audience, including researchers, clinicians, public health professionals, and students
    Anmerkung: English
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  • 2
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9780854663040 , 9780854663064 , 9780854663057
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (108 p.)
    Schlagwort(e): Immunology ; Agent ; Host ; General Environment ; Vaccines ; Sublicinic Stage (Molecular) ; Clinical Stage ; Complications ; Early Diagnosis ; Treatment of Complications ; Death Prevention ; Sequelae Management ; Rehabilitation
    Kurzfassung: This book discusses multisystem inflammation syndrome (MIS), a new complication of COVID-19 in children and adults. The book examines the evolution of MIS as well as its causes, symptoms, complications, and more
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  • 3
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837699520 , 9781837699544 , 9781837699537
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (132 p.)
    Schlagwort(e): Immunology ; Pathology ; Differential Diagnosis ; Morphology ; Classification of Granulomatous Disease ; Clinical Symptoms ; Skin Tests ; Pulmonary Sarcoidosis ; Lymphadenopathy ; Special Stains ; Abdominal Sarcoidosis ; Neurosarcoidosis ; Skin Changes
    Kurzfassung: Sarcoidosis is a generalized, systemic, and specific granulomatous disease involving many organs and systems. Diagnosis of sarcoidosis is challenging, especially when mediastinal lymph nodes and lungs are not affected. The symptoms of sarcoidosis depend on its location. Differential diagnosis of sarcoidosis among the other specific granulomatous diseases is difficult, particularly with tuberculosis on biopsy. The etiology of sarcoidosis is still unknown, but this book offers insights and explanations. It also presents guidelines for treatment
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  • 4
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9780854660797 , 9780854660810 , 9780854660803
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (132 p.)
    Schlagwort(e): Immunology ; Osteoclasts ; Osteoblasts ; Osteocytes ; Bone Remodelling ; Pathophysiology of Osteoporosis ; Immunoporosis ; Imaging ; DEXA ; Biochemical Markers ; Immune Markers ; Vitamin D ; Calcium
    Kurzfassung: Osteoporosis is defined as a systemic bone loss disease exemplified by the deterioration of bone tissues and low bone mineral density (BMD), subsequently leading to an enhanced risk of developing fragility-related fractures. It’s a chronic inflammatory condition and is the 4th most burdensome chronic disease after ischemic heart disease, dementia, and lung cancer, with a huge economic burden on the world economy. This skeletal disorder affects predominantly women compared to men, and the risk increases with age. Although currently available therapies to treat osteoporosis are effective, side effects (real and perceived) are impediments to treatment adherence by the patients. Thus, there is an exigent need for renewed interest in managing osteoporosis with a better understanding of the pathophysiology, diagnosis, and treatment regime so that safer and more effective management and treatment modalities can be developed. Research in the last decade has led to enormous interest in the pathophysiology of osteoporosis. Importantly, the immune system is now an established player in the development of osteoporosis (Immunoporosis). Also, various off-the-track management and treatment approaches (probiotics, Synbiotics, FMT, etc.) are now being considered for managing osteoporosis. The present edited book will compile the latest trends and knowledge in the field, thereby creating a novel knowledge database for effective and efficient management and therapy of osteoporosis
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  • 5
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837687619 , 9781837687602 , 9781837687626
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (406 p.)
    Serie: Infectious Diseases 23
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Chlamydia infections continue to pose a serious socioeconomic burden globally. Despite advances in diagnostic tests in recent decades, chlamydial infections still cannot be controlled, neither in developed countries nor in developing countries. Chlamydial infections date back to the beginning of recorded human history. Trachoma caused by Chlamydia trachomatis, which progresses to blindness, is mentioned in ancient Chinese inscriptions and Egyptian scrolls. Today, we must better apply our knowledge against this clever and evolving obligate intracellular parasitic microorganism. Chlamydia - Secret Enemy from Past to Present examines chlamydial infections using a comprehensive multidisciplinary approach. It discusses the microbiology, clinical presentation, and current approaches in the diagnosis and treatment management of chlamydial infection from the viewpoint of different clinics as well as includes relevant and recent literature
    Anmerkung: English
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  • 6
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837681655 , 9781837681648 , 9781837681662
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (156 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book offers a comprehensive overview of recent trends in viral outbreaks, covering general concepts of immunobiology of infections, viral outbreaks, pathology, virology, viral genomics, viromes, and antiviral pharmacology. It also discusses current clinical recommendations for managing various viral diseases, highlighting ongoing issues, recent advances, and future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of viral outbreaks, whose in-depth understanding is crucial to protect humanity from further losses of resources and economies due to viral diseases. It provides an overview of recent developments in the detection, monitoring, treatment, and control of several viral diseases that have caused recent epidemics or pandemics
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  • 7
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803567501 , 9781803567495 , 9781803567518
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (100 p.)
    Serie: Infectious Diseases 21
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Bacterial sexually transmitted infections (STIs) are among the most widespread infections worldwide, causing major health problems. Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention is a collection of chapters written by experts in the field from all over the globe. It includes recent scientific knowledge and advances in various approaches to the diagnosis, control, treatment, and management of bacterial STIs, depending on available resources and facilities. It presents research from the literature as well as different viewpoints to open new perspectives in this field. It is designed to improve the knowledge of those interested in bacterial STIs and new methods for their diagnosis and treatment
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  • 8
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803567143 , 9781803567136 , 9781803567150
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (84 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The first roundworm identified in humans was Ascaris, described by Linnaeus in 1758. Rudolphi’s 1808 classification was the first to describe the Nematoidea. With the development of new molecular techniques, classification and phylogenetic research have also frequently changed; in 2019 a new classification, the phylum Nematoda, was created based on evolutionary relationships, developmental and morphological features and recent molecular evidence. Nematodes, which include hookworms, whipworms, threadworms, and soil-borne worms, are one of the oldest disease-causing creatures, dating back to Ancient Greek, Roman and Mesopotamian civilizations. Most commonly affecting children and women, the disease causes developmental disorders, cognitive impairment and death, with symptoms primarily affecting the organs they inhabit. In this book, the historical background, biology, transmission routes and geographical distribution of some roundworms affecting human health are discussed
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  • 9
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803553467 , 9781803553450 , 9781803553474
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (132 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Advances in the understanding of neglected tropical diseases (NTDs) are inspiring the scientific community to investigate their eco-epidemiology and physiopathology, and to employ new biotechnological tools to fight against these devasting and complex infectious diseases which are associated with poverty. The topics covered include the employment of digital PCR and next-generation sequencing strategies to diagnose NTDs in hosts and reservoirs in urban and rural areas, and new findings on insects’ reproductive biology that are enabling different vector control strategies. Eco-epidemiology of arboviruses in Latin America and physiopathology of Burili disease caused by Mycobacterium ulcerans are discussed, as is molecular characterization of Plasmodium vivax circumsporozoite protein (CSP) and its use in the epidemiology of malaria and vaccine development. Finally, the origin and pathogenic role of a serine protease inhibitor of Trypanosoma cruzi (TcISP2), the causative agent of Chagas disease, are explored
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  • 10
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803567921 , 9781803567914 , 9781803567938
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (256 p.)
    Serie: Infectious Diseases 20
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Malaria remains a leading cause of morbidity and mortality worldwide. Children in Africa and selected regions of Asia and Southern America are especially widely affected. Written by expert research teams, this book describes different aspects of the epidemiology, pathobiology, diagnosis, prevention, and treatment of malaria. Chapters highlight current research as well as the gold standards for diagnosis and treatment of the disease, examining recent advances, remaining pitfalls, and novel ideas about prophylaxis and therapy
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  • 11
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837680726 , 9781837680719 , 9781837680733
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (206 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book synthesizes the key concepts of immunosuppression and immunomodulation. A comprehensive understanding of these processes is necessary to develop vaccines and therapeutic interventions for diseases. This book examines the role of information molecules such as cytokines and chemokines and other proteins secreted by the host upon interacting with the pathogen(s) that modulate and suppress the immune system and assist the pathogen(s) in causing disease. Chapters discuss the modulation of inflammation, signaling pathways, the interaction of immune cells, and resulting immunity as well as its suppression
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  • 12
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837688715 , 9781837688708 , 9781837688722
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (74 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Celiac disease is an autoimmune disease that primarily affects the small intestine, causing chronic inflammation and sometimes villous atrophy. It is related to the ingestion of gluten products and affects genetically susceptible people. This book provides a comprehensive overview of celiac disease, presenting information on its diagnosis and management
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  • 13
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837685066 , 9781837685059 , 9781837685073
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (144 p.)
    Serie: Infectious Diseases 19
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Echinococcosis is a neglected parasitic disease caused by Echinococcus spp. of the family Taeniidae. The prevalence of the disease is increasing worldwide due to industrialization and climate change. This book provides a comprehensive overview of echinococcosis, including information on epidemiology, geographic distribution, diagnosis, management, and prevention
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  • 14
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837684816 , 9781837684809 , 9781837684823
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (94 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Natural killer (NK) cells are immune cells that can eliminate pathogenic microorganisms, aging cells, and tumor cells. State-of-the-art renewal has indicated the feasibility of large-scale preparation of autogenous and allogeneic NK cells from a variety of sources including peripheral blood, umbilical cord blood, placental blood, NK cell lines, and even stem cells such as pluripotent stem cells and hematopoietic stem cells. In the meantime, a range of methodologies has been developed for ex vivo expansion and activation of NK cells such as monolayer culture, coculture with trophoblast cells, bioreactors, cytokine cocktails, and physicochemical irritation. NK cell-based cytotherapy has proven effective for a variety of hematologic malignancies and metastatic solid tumors. This book provides a comprehensive overview of NK cell-based cytotherapy for cancer treatment, immunosurveillance, and immunotherapy
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  • 15
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803565910 , 9781803565903 , 9781803565927
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (212 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Immune Checkpoint Inhibitors - New Insights and Recent Progress explores a vast array of subjects related to immune checkpoint inhibitors and presents novel insights in this emerging field. Chapters address such topics as mechanistic approaches of emerging immune checkpoint inhibitors, their role in clinical and pre-clinical trials, the manipulation of the system by immune-related adverse events that hinder the utility of these immune molecules, and the predictive and prognostic aspects of these molecules as biomarkers of response in immunotherapy. The book is useful for students, clinicians, and scientists to gain updated information on managing patients treated with immune checkpoint inhibitors
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  • 16
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837687404 , 9781837687398 , 9781837687411
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (230 p.)
    Serie: Physiology 19
    Schlagwort(e): Immunology
    Kurzfassung: Phagocytosis, as an innate immune defense mechanism, is the first process to respond to pathogens. It is also one of the initiating branches of an adaptive immune response. This book provides a comprehensive overview of phagocytosis and related cells in the immune response. It presents the basics of phagocytosis as well as discusses management and therapeutic strategies for infections
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  • 17
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803560571 , 9781803560564 , 9781803560588
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (104 p.)
    Schlagwort(e): Immunology
    Kurzfassung: In healthy humans, effector immune cells are activated by the presence of pathogens. Various signaling pathways coordinate the growth and proliferation of the immune cells to fight the invading pathogen and keep the host healthy. A portion of white blood cells known as regulatory T cells (Treg) help to control the rapid proliferation of effector immune cells including effector T cells as well as antigen-presenting cells to make sure the inflammation is kept in check. When Treg cells are depleted or undergo loss of suppressive functionality, hyperinflammatory disease results. However, Treg depletion can also provoke and enhance tumor immunity. Therefore, targeting Treg cells is a promising approach for both autoimmune disease and cancer immunotherapy. To attenuate or enhance Treg-mediated immune suppression, it is necessary to find a specific molecular marker that can selectively and reliably differentiate between Treg and effector T cells. Further elucidation of the cellular and molecular processes underlying the development and function of regulatory immune cells will help to establish new strategies for the treatment and prevention of immune-mediated disease
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  • 18
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803568461 , 9781803568454 , 9781803568478
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (150 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book provides a comprehensive overview of allergies, ranging from environmental allergies to food allergies. It discusses the diagnosis and management of allergic reactions, including early exposure to allergens, immunotherapy, and stem cell treatment. It includes eight chapters organized into four sections. Chapters discuss some of the most frequent allergic diseases, such as atopic dermatitis and chronic urticaria. There is also a chapter dedicated to treating allergies during the COVID-19 pandemic
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  • 19
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837682065 , 9781837699858 , 9781837682072
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (190 p.)
    Serie: Infectious Diseases 17
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The study of staphylococci has a long way to go, due to the great significance both for humans and for dairy or companion animals of their large number of virulence factors. Their resistance to antibiotics makes these microorganisms become highly pathogenic species that can cause infections ranging from mild to fatal. Staphylococci, especially S. aureus and strains resistant to methicillin (MRSA), are among the most studied microorganisms worldwide. This book covers recent advances in the study of staphylococci. The book is divided into four sections that cover four important events for the study and combat of staphylococci: colonization, epidemiology and pathogenesis, diagnosis, and new treatments. Staphylococci can present a broad spectrum of resistance to antibiotics, which is why their elimination has become difficult. The final section of the book is devoted to new compounds for the fight against staphylococci. We hope that the information contained in this book will be useful for the study and investigation of these medically important microorganisms
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  • 20
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803569246 , 9781803569239 , 9781803569253
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (262 p.)
    Serie: Infectious Diseases 22
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Dengue Fever in a One Health Perspective - Latest Research and Recent Advances presents studies on dengue fever (DF) and dengue virus (DENV) that discuss eco-epidemiology, physiopathology, and new biotechnological tools to fight against this important disease in the context of the World Health Organization’s One Health strategy. The book is organized into five sections: “Epidemiological Aspects”, “Environmental Aspects”, “Pathogenicity”, “Diagnosis and Treatment” and “Management Strategies”. The chapters address topics such as DF prevalence and management in a Chinese county, the risk of DF in American children younger than 15 years, the silent transmission of DENV by asymptomatic individuals, the use of X-ray and ultrasound to identify severe DF cases, gene-silencing techniques to investigate biological aspects of DF, viral genomic surveillance to promote early intervention in DF epidemics, and much more
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  • 21
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781837686629 , 9781837686612 , 9781837686636
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (150 p.)
    Serie: Infectious Diseases 24
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The true incidence of histoplasmosis remains difficult to ascertain due to the lack of mandatory notification of the disease, resulting in an underestimation of its actual burden. Given the high mortality rate, especially for disseminated forms in immunocompromised patients, we must remain vigilant against fungal disease. This book, born out of a deep desire to expand our knowledge of this fungal disease and update the latest findings, is intended to assist clinicians in recognizing and effectively managing histoplasmosis, especially those who live outside endemic areas and are less familiar with this pathology. With the latest insights into epidemiology, pathophysiology, clinical manifestations, and diagnostic approaches for both immunocompetent and immunodeficient patients, this comprehensive volume provides infectious disease specialists, pulmonologists, and laboratory physicians with the tools they need to optimize the management of histoplasmosis
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  • 22
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    ISBN: 9781803563480 , 9781803563473 , 9781803563497
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (200 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This Edited Volume “Systemic Lupus Erythematosus - Pathogenesis" and Management” is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of lupus erythematosus. The book comprises single chapters authored by various researchers and edited by an expert active in the lupus research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on lupus, and open new possible research paths for further novel developments
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  • 23
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9780850142532 , 9780850142525 , 9780850142549
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (140 p.)
    Serie: Infectious Diseases 26
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Despite the development of numerous antimicrobial agents, the successful eradication of bacterial infections remains a challenge, and bacteria continue to pose a major public health threat. It is estimated that, due to the increasing prevalence of antibiotic resistance, infectious diseases will become a leading cause of death by 2050. The current annual focus is on the challenges and advantages in the prevention and diagnosis of infections caused by ESKAPE pathogens. The book also includes a dedicated chapter on the diagnosis of tuberculosis, one of the leading infectious causes of death worldwide. Additionally, readers will find chapters describing achievements in the diagnosis and detection of common gastrointestinal tract pathogens, Listeria monocytogenes and Campylobacter jejuni, authored by experts in their fields
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  • 24
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    ISBN: 9781837697519 , 9781837697496 , 9781837697502
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (116 p.)
    Schlagwort(e): Immunology ; Human Genetics ; Immunogenetics ; Transplantation ; DNA ; Solid Organ ; Hematopoietic System ; Panel Reactive Antibody (PRA) ; Cross Match Diagnosis ; Treatment ; Immune System ; Immunology ; HLA
    Kurzfassung: Our understanding of immunogenetics is growing rapidly with new and exciting developments in all fields. This book provides a comprehensive overview of transplantation immunogenetics. Chapters address such topics as immune tolerance, human leukocyte antigens (HLAs) and transplantation, immunity and viral epidemics, and more
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  • 25
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    ISBN: 9781803562438 , 9781803562421 , 9781803562445
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (110 p.)
    Schlagwort(e): Immunology ; imaging ; pathogenesis ; pathophysiology ; magnetic resonance imaging ; computed tomography ; qol
    Kurzfassung: Ankylosing Spondylitis - Recent Concepts provides a comprehensive overview of ankylosing spondylitis (AS). It includes five chapters organized into two sections. The first section is dedicated to the history of AS, the chronology of diagnostic/classification criteria across the years, and imaging in AS. The second section examines the molecular genetics, immunology, enteric microbiome, and pharmacologic and nonpharmacologic treatment of AS
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  • 26
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839686399 , 9781839686382 , 9781839686405
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (86 p.)
    Serie: Infectious Diseases 13
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Pneumonia is an infectious disease of the pulmonary alveoli that leads to extensive morbidity and mortality. This book presents a comprehensive overview of this disease with chapters on hospital-acquired pneumonia, drug-related problems and hospital readmissions, secondary bacterial infections in viral pneumonia, and iron acquisition in pneumococci
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  • 27
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    ISBN: 9781839699184 , 9781839699177 , 9781839699191
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (66 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Many people worldwide suffer from sarcoidosis, which can be cured or controlled via immune system modulation and immunotherapy. This book presents a comprehensive overview of sarcoidosis and related aspects. It discusses the cell signaling pathways and molecular mechanisms involved in sarcoidosis as well as pathophysiology, diagnosis, management, and treatment of the disease
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  • 28
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803558868 , 9781803558851 , 9781803558875
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (130 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book discusses the significance of interferon (INF) in the clinical aspects of the disease. Chapters address the biological, chemical, and physiological aspects of IFN and how IFN can assist various targeted health interventions. The information contained herein is useful for designing IFN gamma–directed strategies for managing various diseases discussed in the text
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  • 29
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839692093 , 9781839692086 , 9781839692109
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (126 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Giant cell arteritis (GCA) is a systemic vasculitis that affects medium- to large-size arteries in which an inflammatory reaction destroys the media of the artery wall with the fragmentation of the elastic lamina, which can result in acute vision loss if not treated in a timely manner. The other common visual symptoms may include diplopia due to cranial nerve palsies and transient visual loss. This book provides a comprehensive overview of GCA, with chapters on epidemiology, cellular and molecular characteristics of the disease, extra-cranial involvement of GCA, medical imaging, and much more
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  • 30
    ISBN: 9781837689446 , 9781837689439 , 9781837689453
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (176 p.)
    Serie: Infectious Diseases 15
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book is an annual collection of reviewed and relevant research chapters authored by various researchers, offering a comprehensive overview of recent studies and developments in the field of Infectious Diseases. It joins work from four areas in this field, Bacterial, Fungal, Parasitic, and Viral Infectious Diseases, each edited by an expert. The global challenges and different living circumstances for people around the globe ask for a deep understanding of various aspects and properties of infectious diseases to ensure a safer and healthier cohabitation of humans and pathogens
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  • 31
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803556253 , 9781803556246 , 9781803556260
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (392 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Macrophages were first discovered in 1882 when Elia Metchnikoff recognized them as important phagocytic cells that can engulf any foreign material, including fungal spores. This discovery has proved to be a milestone in establishing the field of innate immunity. Macrophages are still ruling the area after 140 years of their discovery. This book explores the diverse role of macrophages in vertebrate immunity, parasitic, bacterial, and viral infections, regeneration, inflammation, and neurological diseases
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  • 32
    ISBN: 9781803555683 , 9781803555676 , 9781803555690
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (400 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book provides updated information on helminth infections, with proposals for new treatments and biological factors of risk, the development of vaccines for the control of helminthiasis and explains the latest research on the field. It also delves into multi-omics, diagnosis, immunology, and novel molecule targets. In addition, the book examines topics such as host-parasite interaction. Key Features: • Provides basic and clinical evidence based on molecular interactions to address the risks and benefits of helminthiasis • Presents the results of new vaccine development • Discusses new and old therapeutic approaches in helminth infections • Delves into advances in the molecular and immune response in helminth infection • Proposes a One Health approach to study helminth infections • Analyzes the controversies and confusions in the management, biology, and control strategies of helminth infections • Examines the basic biology of helminth parasites
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  • 33
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803558561 , 9781803558554 , 9781803558578
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (94 p.)
    Serie: Infectious Diseases 14
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Although there are thousands of parasites all over the world, Schistosoma spp. are unique in terms of their morphology. Although they have separate bodies as “male” and “female,” they live in such a way that the female resides within the male. Schistosoma spp., classified in the family of trematodes, has about twenty members, five of which cause a disease called schistosomiasis (or bilharzia) in humans. This disease causes a variety of symptoms, ranging from simple skin lesions to a dramatic clinical scenario of bladder carcinoma. Although there are many different diagnostic and therapeutic methods, schistosomiasis is still an important threat to humans and a significant challenge for healthcare professionals. This book discusses the morphology, geographic distribution, and evolution of Schistosoma spp., as well as the diagnosis, treatment, and prevention of schistosomiasis
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  • 34
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781803556673 , 9781803556666 , 9781803556680
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (162 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book discusses RNA viruses and their potential to cause pandemics, such as the coronavirus pandemic the world is currently experiencing. It discusses different types of RNA viruses, including SARS-CoV2, respiratory syncytial virus (RSV), influenza, HIV, and others. Chapters examine the epidemiology, transmission, pathogenesis, diagnosis, prevention, and control using the One Health approach
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  • 35
    ISBN: 9781803556918 , 9781803556901 , 9781803556925
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (182 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Even 110 years after its discovery, Chagas disease is still an important public health problem, especially in Latin America where it is endemic. The limited effect of current treatments in the chronic phase of the disease, as well as the lack of information about disease progression, are crucial challenges that justify the intense research on this illness. The interaction between the etiological agent Trypanosoma cruzi and its invertebrate and vertebrate hosts involves the regulation of the parasite virulence and host immune responses. T. cruzi presents mechanisms to evade host defenses, including resistance to oxidative species and vesicles secretion, among many others. In this context, a better understanding of the biochemical and molecular features of the parasite’s success inside its hosts could contribute to the development of novel anti-T. cruzi strategies such as prototypes of drugs and vaccines. This book discusses Chagas disease and its etiological agent, including information on relevant clinical aspects such as diagnosis, treatment, biomarkers, and so on. It also presents information about cellular, molecular, and biochemical characteristics of the parasite-host interactions
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  • 36
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839690907 , 9781839690891 , 9781839690914
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (102 p.)
    Serie: Infectious Diseases 12
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The chikungunya virus (CHIKV) is an RNA virus that is transmitted to humans by Aedes mosquitos commonly found in tropical and subtropical countries. In humans, CHIKV causes an infection with symptoms strikingly like those of the dengue virus and Zika disease, both of which are also transmitted to humans by the same genus of mosquitos. This book delves into the history of the disease and the molecular characterization of the virus. It sheds light on modern diagnosis tools that allow unambiguous identification of CHIKV infection. In addition, this book addresses the epidemiology of chikungunya fever, the distribution and spread of the disease, and the promising approaches under consideration for preventing and treating the disease
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  • 37
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839692307 , 9781839692291 , 9781839692314
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (98 p.)
    Serie: Veterinary Medicine and Science 9
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Despite significant worldwide progress in fighting rabies, a zoonotic viral disease, it remains an important public health concern, causing approximately 50,000 human cases per year. This book summarizes current knowledge regarding rabies, the prevalence and genetic diversity of the rabies virus, and modern approaches to rabies diagnosis, prevention, and treatment. It is a useful resource for scientists, doctors, and students
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  • 38
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839680823 , 9781839680816 , 9781839680922
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (256 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Leishmaniasis is a major global health challenge, affecting approximately 12 million of the poorest people in 100 countries. It is a deforming and fatal disease in the visceral form. Therapies for leishmaniasis are numerically restricted, basically consisting of the administration of miltefosine, pentavalent antimonials, amphotericin B, or pentamidine. This is an important vulnerability against therapy efficiency that must be overcome by the scientific community. This book discusses important aspects of the disease, such as treatment, epidemiology, and molecular and cell biology. The information contained herein is important for young researchers as they seek to develop safe and effective treatments for this neglected tropical disease
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  • 39
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789238884 , 9781789238877 , 9781789851410
    Sprache: Englisch
    Seiten: 1 Online-Ressource (128 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book is a collection of chapters that discuss methodologies, resources, and technologies by dedicated authors. This book has addressed the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. All chapters have focused on the fate of differentiated macrophages and discussed molecular pathways that are important for the pathologic role of macrophages. I am confident that our readers will find this book useful in designing immune mediated strategies for managing various diseases that this book is based on
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  • 40
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839629266 , 9781839629259 , 9781839629273
    Sprache: Englisch
    Seiten: 1 Online-Ressource (120 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book provides an overview of the globally concerning and emerging public health RNA viruses like SARS-CoV2, Ebola virus, FMD disease, and others. The main drive to publish this book was to present information on the molecular epidemiology pattern, transmission dynamics, host response factor, RNA viral infection, RNA virus evolution, molecular biology of RNA viruses, pathogenesis mechanism and phylogenetic analysis causing viral diseases among humans. This book will help to provide updated research information to the policymaker or planner for further diagnosis with genotyping tools, control, and prevention for further outbreaks of diseases from RNA viruses in tropical and subtropical countries
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  • 41
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839684173 , 9781839684166 , 9781839684180
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (228 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book discusses contemporary ideas on different molecular and immunological aspects of diseases. Different signaling mediators drive the production of messenger molecules that mediate their action, leading to the elicitation/suppression of immune responses. It provides a balanced approach to the study of different molecular phenomena that eventually drive infection outcomes and that can be manipulated for therapeutic benefits
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  • 42
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839687839 , 9781839687822 , 9781839687846
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (100 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Infectious microbial agents such as viruses, bacteria, fungi, and parasites can cause pathological disorders and even death in organisms exposed to the environment. However, organisms have an immune system to control infection caused by pathogens. The immune system is divided into the innate and the adaptive immune systems. The innate immune system is the first mechanism to respond to infections, whereas the adaptive immune system is based on immune memory. This book provides an overview of antiviral and antibacterial immune responses in different immune-reactive organs and across different animal species, from higher to lower vertebrates
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  • 43
    ISBN: 9781839693953 , 9781839693946 , 9781839693960
    Sprache: Englisch
    Seiten: 1 Online-Ressource (146 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book provides updated information to scientists and clinicians on taeniosis/cysticercosis, a parasitic infection caused by eating undercooked beef or pork that is a serious health and veterinary problem in many developing countries. It discusses incidence, risk factors, diagnosis, immunology, symptoms, rare manifestations, and advances in treatment including vaccination and novel drug therapies
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  • 44
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839684906 , 9781839684890 , 9781839684913
    Sprache: Englisch
    Seiten: 1 Online-Ressource (128 p.)
    Serie: Infectious Diseases 11
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Epstein-Barr virus (EBV) is a fascinating microorganism, as a 'double-facetted' viral agent. After primary infection, it can persist throughout a person's lifetime in a latent form, from which it can reactivate following specific stimuli (i.e., immunodepression). Unlike other herpesviruses, EBV reactivates a countless number of times with such a high replication rate that it is unable to be controlled by conventional anti-herpesvirus drugs. Moreover, for various reasons, no vaccine is currently available in the market. This book presents a comprehensive overview of EBV, including information on its potential for oncogenic activity, its various isolates, and possible vaccine candidates
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  • 45
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839694585 , 9781839694578 , 9781839694592
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (394 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Infection is a common clinical condition that may cause local inflammation but, in some cases, can lead to systemic inflammation, with sepsis and organ dysfunction. Septic shock is a condition of inadequate tissue perfusion and cellular use of oxygen due to the cytotoxic action of bacterial toxins. There is no relationship between the pathological characteristics and the severity of the primary septic outbreak and the development of septic shock, and the time that elapses until the start of the shock is not predictable. Thus, knowledge of the pathophysiology of septic shock is fundamental for treatment. This book presents a comprehensive overview of infectious agents and their therapeutic control, pathological conditions with infective etiology such as diabetic foot osteomyelitis and infections in neurosurgery, and the pathophysiology, diagnosis, and management of sepsis
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  • 46
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839684050 , 9781839684036 , 9781839684067
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (168 p.)
    Serie: Rheumatology 5
    Schlagwort(e): Immunology
    Kurzfassung: Systemic lupus erythematosus (SLE) is a multisystem, immune-mediated, inflammatory disease of unknown etiology. It is difficult to diagnose and thus effective intervention in SLE patients is often delayed. This book is a comprehensive guide to lupus, with chapters on diagnosis, assessment, treatment, the link between lupus and endocrinopathies, lupus and pregnancy, and advances in therapeutics. The book is presented by devoted authors who sought the latest evidence-based data to provide a well-structured display aiming at setting standards for best practice guidelines in the diagnosis and management of each and every section discussed in the “Lupus- Need to Know.”
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  • 47
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839625367 , 9781839625350 , 9781839625374
    Sprache: Englisch
    Seiten: 1 Online-Ressource (92 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Celiac disease is a common autoimmune disorder triggered by eating gluten that affects at least 1% of the world's population. Despite many years of effort, its pathogenesis is still not understood completely. This book discusses several important aspects of celiac disease, including its primary contributor, the DQ2 gene. It also examines dysfunctional immune checkpoints, causes and treatments of refractory celiac disease, and the status of the gluten-free food market
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  • 48
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839687747 , 9781839687730 , 9781839687754
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (312 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Graves’ disease is caused by autoantibodies to the thyroid gland that mimic thyroid-stimulating hormone, causing the gland to overproduce thyroid hormone. This speeds the metabolism of the patient and can lead to dangerous conditions including atrial fibrillation and heart failure. Mainstays of treatment have included antithyroid medication, surgical removal of the thyroid gland, and more recently, radiofrequency ablation of the thyroid gland. Advancements in diagnostic testing have enhanced our understanding of the natural course of the disease, creating additional therapeutic options. Enhanced understanding of the autoimmunity behind the disorder may lead to therapeutic options that address the underlying autoimmunity. This book provides a comprehensive review of these enhancements and how they have resulted in changes in common clinical practice
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  • 49
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839683701 , 9781839683695 , 9781839683718
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Immune-based therapies are being studied extensively in a variety of immunological conditions due to their high precision and sensitivity. Monoclonal antibody (mAb) technology is a major advancement in the treatment of several infectious diseases, malignancies, and immunological disorders. This book provides comprehensive information about technologies, characterization, and application of mAbs in the clinic and laboratory
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  • 50
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839682926 , 9781839682919 , 9781839682933
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (154 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Helicobacter pylori is a universally distributed bacterium that affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease, and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book, there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacterium and studies and discussions about its aspects are welcome to the medical and scientific communities
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  • 51
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839627439 , 9781839627422 , 9781839627446
    Sprache: Englisch
    Seiten: 1 Online-Ressource (252 p.)
    Serie: Infectious Diseases 10
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Staphylococcus aureus is a coccus, gram-positive, non-spore forming, and non-motile bacterium. Its commensal and opportunistic capabilities make it able to colonize different sites of animals and humans. Resistance to antibiotics has resulted in development of new strains and new types within strains. Types of methicillin-resistant S. aureus (MRSA) include hospital-acquired MRSA (HA-MRSA), community-acquired MRSA (CA-MRSA), and livestock-acquired MRSA (LA-MRSA). There are also new strains like vancomycin-resistant S. aureus (VRSA) and vancomycin-intermediate S. aureus (VISA). Expansion in resistance is expected to give rise to newer strains resistant to antibiotics such as macrolide (erm gene), tetracycline (tet genes), mupirocin (mupR), and fusidic acid (fusD). Alternative approaches like nanoparticles, bacteriophages, phytochemicals, and more are required to tackle this pathogen. This book contains information on epidemiology, resistance mechanisms, and alternative ways to curtail S. aureus infection, as well as future research opportunities
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  • 52
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781838807665 , 9781838807658 , 9781838807672
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (414 p.)
    Schlagwort(e): Immunology
    Kurzfassung: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages
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  • 53
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839689451 , 9781839689444 , 9781839689468
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (110 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book provides an overview of norovirus, a viral infection that adversely affects the gastrointestinal system. Unfortunately, there is no specific treatment available for this illness. As such, the World Health Organization (WHO) has identified norovirus as a priority disease for vaccine development. Chapters in this edited volume cover such topics as examination methods and genome mechanisms of norovirus, and clinical and pharmaceutical developments in managing this illness
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  • 54
    ISBN: 9781789850987 , 9781789850970 , 9781839627781
    Sprache: Englisch
    Seiten: 1 Online-Ressource (156 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Brucellosis is an important zoonotic disease. More than half a million new cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of patients are living in developing countries. Brucellosis is a systemic infection with a broad clinical spectrum, ranging from an asymptomatic disease to a severe and fatal illness. Clinical and laboratory features vary widely. The main presentations are acute febrile illness, localized infection, and chronic infection. Laboratory tools for diagnosis of brucellosis include culture, serology, and polymerase chain reaction (PCR). The goal of brucellosis therapy is to control the illness and prevent complications, relapses, and sequelae. Important principles of brucellosis treatment include use of antibiotics with activity in the acidic intracellular environment, use of combination regimens, and prolonged duration of treatment. This book is the result of several months of outstanding efforts by the authors and the revision of the content by experts in the field of brucellosis. This book is a valid resource and is intended for everyone interested in infectious disease to learn the most important aspects of brucellosis
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  • 55
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839681240 , 9781839681233 , 9781839681257
    Sprache: Englisch
    Seiten: 1 Online-Ressource (104 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Our immune system is equipped with a series of defence mechanisms to recognise and respond to non-self molecules. Although essential for fighting off infections and preventing cancers, destructive immune responses pose a considerable challenge in autoinflammation and transplantation. Currently available immunosuppressants help to control destructive immune responses. However, management of side-effects of lifelong immunosuppression, including cancer development and reduced survival, remain major problems. For this reason, an increasing amount of interest is directed towards the natural specific regulatory mechanism of the immune system. A better understanding of these mechanisms holds the key. This book presents a comprehensive overview of immune suppression in transplantation, cancer and viral infections. Chapters cover modulation of Treg as well as the new era of immunotherapy
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  • 56
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789846454 , 9781789846447 , 9781789855746
    Sprache: Englisch
    Seiten: 1 Online-Ressource (132 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Macrophages are the sentinels of the immune system whose role has evolved beyond providing aseptic conditions to homeostasis, immune regulation, development, and behaviour. These cells have varied ontogenetic origins which reflects in their phenotypic and functional heterogeneity. Macrophage functions are fine-tuned by exogenous and endogenous signals and once tweaked, the information is included in their genetic makeup, albeit not indefinitely. Subversion of the macrophage functions is the hallmark of many pathogenic organisms and modulation of macrophage activity is pivotal to many therapeutic strategies. Fascinating and rapid developments in this field have necessitated the maintenance of currency of knowledge. This book provides a current account of information on varied topics in macrophage biology. Literature surveys have been presented in a captivating and lucid language. The contributing authors have also provided brief accounts of their own research. Every chapter provides a future perspective of what more could be achieved in the context of the current knowledge. The book will be of interest to students and researchers in microbiology, immunobiology, translational research, pathology, and related fields
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  • 57
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    ISBN: 9781838801700 , 9781838801694 , 9781838801847
    Sprache: Englisch
    Seiten: 1 Online-Ressource (138 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Systemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission. This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management. In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies
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  • 58
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839628337 , 9781838810351 , 9781839628344
    Sprache: Englisch
    Seiten: 1 Online-Ressource (178 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis
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  • 59
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789859706 , 9781789859690 , 9781838803001
    Sprache: Englisch
    Seiten: 1 Online-Ressource (78 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: More than 10,000 patients are hospitalized every year with Legionnaires' disease in the United States alone. Legionnaires' disease is also an important public health topic as it involves environmental and public issues, as far as its spread and prevention are concerned. With an aging population, increasing number of transplants, increasing use of immunosuppressive medications, and compromised immunity due to multiorgan system disease, Legionnaires' disease is emerging as an important disease
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  • 60
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    ISBN: 9781838804794 , 9781838804787 , 9781838804824
    Sprache: Englisch
    Seiten: 1 Online-Ressource (124 p.)
    Serie: Infectious Diseases 6
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: We are very pleased to present this book dealing with echinococcosis. The chapters of this book are written by surgeons, radiologists, and parasitologists from different hospitals in several countries as Tunisia, Turkey, Indonesia, Nigeria, Romania, Chile and Iraq. This book is intended for clinicians, radiologists, internists, and surgeons involved in the management of patients with echinococcosis
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  • 61
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    ISBN: 9781839625336 , 9781839625329 , 9781839625343
    Sprache: Englisch
    Seiten: 1 Online-Ressource (168 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Rheumatoid Arthritis - Other Perspectives towards Better Practice sheds light on the disease process of rheumatoid arthritis as well as the disease’s related comorbidities. Chapters cover such topics as immune-pathogenic theories, classification criteria, available composite measures of disease assessment, and latest available therapeutic approaches
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  • 62
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    ISBN: 9781838811594 , 9781838811587 , 9781838811600
    Sprache: Englisch
    Seiten: 1 Online-Ressource (128 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The relationship between herpesviruses and humans probably dates from thousands of years ago. In the last few decades, many aspects of herpesvirus infections have been understood, such as infections with a range of manifestations (severe, mild, or subclinical). Herpesvirus can remain latent during a lifetime and sometimes their reactivation can cause different clinical features in the patient. Several conditions have been related to herpesvirus reactivation such as complications in transplant organ recipients and immune regulatory modification in the elderly. Aspects of human herpesvirus simples, varicella-zoster virus, and cytomegalovirus are presented and discussed in this book
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  • 63
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789843583 , 9781789843576 , 9781839680014
    Sprache: Englisch
    Seiten: 1 Online-Ressource (248 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental models, the chapters selected for this book bring to readers at different academic levels updated and practical data on inflammation. Find out what drives interdisciplinary medical research on inflammation and enjoy this informative collection
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  • 64
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    ISBN: 9781839629624 , 9781839629617 , 9781839629631
    Sprache: Englisch
    Seiten: 1 Online-Ressource (92 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Histoplasma and Histoplasmosis is a book on epidemiology, diagnosis, and treatment of histoplasmosis. It is an all-inclusive source of knowledge for both specialist and non-specialist mycologists at various levels of training or work experience.Through collaborative efforts of the authors and the editor, this book provides up-to-date information on the global distribution of histoplasmosis, an updated estimation of the burden of histoplasmosis in Asia, and recent advances in laboratory diagnosis and treatment of histoplasma and histoplasmosis. This volume is an invaluable source of knowledge for trainees and practitioners alike
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  • 65
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    ISBN: 9781839685354 , 9781839685347 , 9781839685361
    Sprache: Englisch
    Seiten: 1 Online-Ressource (98 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Skin is a natural barrier to infection. Surgical breakage of skin can lead to surgical site infections (SSIs). SSIs are relatively common and constitute a problematic issue in surgical procedures. Most common organisms include Gram-positive, such as Staphylococcus and Streptococcus, as well as Gram-negative, such as Pseudomonas and others, bacteria. The extent and outcome of SSI can vary widely depending on the procedure, organism, extent, and other factors, and can result in discomfort, severe morbidity, or even life-threatening conditions.It is thus mandatory to be aware of and follow WHO and CDC guidelines for the prevention of SSIs and to reduce risk factors for acquisition. This book sheds light on certain aspects related to SSIs and how to avoid them
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  • 66
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    ISBN: 9781789856491 , 9781789852028 , 9781789856507
    Sprache: Englisch
    Seiten: 1 Online-Ressource (196 p.)
    Serie: Infectious Diseases 7
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Dengue Fever in a One Health Perspective underlines important aspects of dengue virus, the most prevalent and life-threatening arbovirus in the world. Over three sections, chapters cover such topics as biological and environmental aspects, physiopathology, molecular biology, diagnosis, and control strategies. The first section provides knowledge on basic aspects of dengue virus biology and its emergence and re-emergence associated to environmental changes. The second section includes two chapters on dengue immunopathology, a drawback in disease control and vaccine development. Finally, the third section examines molecular biology tools employed in dengue virus immunopathogenesis studies, diagnosis, drug design, and in the use of vectors as sentinels in surveillance and vector biology studies
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  • 67
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    ISBN: 9781839625244 , 9781839625237 , 9781839625251
    Sprache: Englisch
    Seiten: 1 Online-Ressource (234 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Gram-negative Escherichia coli (E. coli) bacteria are the most numerous commensal aerobic germs located in the human colon. Diarrhea caused by E. coli pathogenic strains is a major cause of death in developing countries, especially the sub-Saharan and South Asian areas. Some strains cause diarrhea, and all of them may produce an infectious disease. This book includes ten chapters covering the main aspects of infections related to E. coli, their pathogenic mechanisms, treatments, and resistance to diverse antibiotics
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    ISBN: 9781789853360 , 9781789853353 , 9781838806637
    Sprache: Englisch
    Seiten: 1 Online-Ressource (112 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Helminthiasis is a disease caused by parasitic helminths such as flukes, tapeworms, filarial worms, and nematodes. These parasites cause diseases that pose serious health problems, especially in developing countries of the world. Helminthiasis is a reflection of poor socio-economic conditions, which impacts on the social life of victims and economic development. Parasitic helminths live in a variety of habitats in their hosts and are far more widespread than we think. Gastrointestinal helminths are the largest group that affects their host directly through feacal-oral routes. This book not only provides insight into antihelminthic resistance in livestock but it also discusses soil transmitted helminths in pregnant women and children and filariasis as a debilitating disease. The book covers the prevention and control of helminthiasis of which adequate diagnosis is crucial. This book helps to close the information gap on helminthiasis, which has otherwise been classified as belonging to the group of neglected diseases and overlooked as a serious cause of morbidity and mortality of humans and domestic animals. The information in this book proposes that helminthiasis needs more global attention
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    ISBN: 9781838803940 , 9781838803933 , 9781839629839
    Sprache: Englisch
    Seiten: 1 Online-Ressource (102 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis
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  • 70
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    ISBN: 9781789855845 , 9781789855838 , 9781838804305
    Sprache: Englisch
    Seiten: 1 Online-Ressource (246 p.)
    Schlagwort(e): Immunology
    Kurzfassung: The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness
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  • 71
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    ISBN: 9781789855500 , 9781789855494 , 9781789850567
    Sprache: Englisch
    Seiten: 1 Online-Ressource (104 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book discusses the emerging challenges of the filovirus infections Ebola and Marburg virus disease. It reviews the complex ecology and role played by bats and other suspected intermediate hosts, including pigs. Also examined are the challenges for other modes of transmission and early diagnosis and detection. The immunology and pathogenesis of the infections and the impact on the host?s immune systems are discussed. The rare occurrence of Marburg virus infection in pregnancy and the long-term consequences of sexual transmission by survivors is further examined. These discussions have the potential to support future management of outbreaks and guide research for vaccines and medication for Ebola and Marburg disease
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  • 72
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    ISBN: 9781789848595 , 9781789848588 , 9781839683398
    Sprache: Englisch
    Seiten: 1 Online-Ressource (180 p.)
    Schlagwort(e): Immunology
    Kurzfassung: The human immune system is a complicated biological network that employs a collection of cells, molecules, and proteins. Cytokines play an important role in regulating the innate and adaptive immune systems by different receptors and signaling pathways. As such, they are also implicated in the occurrence of different disorders and diseases. This book presents a comprehensive overview of immunology, the immune system, and cytokines. Chapters cover such topics as the role and importance of tumor necrosis factor (TNF) in the human body, the association of cytokines with different disorders and diseases, and the role of cytokines in dentistry
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  • 73
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    ISBN: 9781838812201 , 9781838812195 , 9781838812218
    Sprache: Englisch
    Seiten: 1 Online-Ressource (134 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book is about the highly infective human papilloma virus (HPV). There are more than 200 strains of HPV, though only a few, like HPV 16 and HPV 18, are oncogenic. HPV infections can lead to cancers of the cervix, vulva, vagina, anus, penis, and oral cavity.Written by authors from across the globe, this book is a comprehensive look at HPV. Chapters cover such topics as the epidemiology of HPV, treatment of the manifestations of HPV, which can include warts on the skin and genitals, diagnosis and management of oral mucosal cancers due to HPV, HPV and pregnancy, and HPV vaccines. It is a useful reference for researchers and scientists in the field, providing them with helpful knowledge to combat and prevent HPV infections and cancers
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  • 74
    ISBN: 9781838800222 , 9781838800215 , 9781838800383
    Sprache: Englisch
    Seiten: 1 Online-Ressource (166 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Vector-Borne Diseases - Recent Developments in Epidemiology and Control utilizes the unique capabilities of open-access publishing to share exciting developments in the biology, diagnosis, and treatment of diseases spread by arthropods. From malaria to dengue to leishmaniasis, the diseases addressed in this book continue to present threats to the life and well-being of millions around the world. The international cast of writers published here provide specific insight into a full spectrum of diseases spread by insects and their close relatives
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  • 75
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    ISBN: 9781789841220 , 9781789841213 , 9781839681080
    Sprache: Englisch
    Seiten: 1 Online-Ressource (184 p.)
    Serie: Infectious Diseases 4
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Each year, malaria kills almost half a million people despite the fact that it is a preventable and curable disease. Malaria has a direct correlation with economic loss due to the need for people to take time off work and the cost of hospital treatments. Undertaking decisive measures to combat malaria is necessary. This book aims to present current approaches in the treatment of malaria. It will be a guide to those working in malaria-endemic regions and cover both diagnosis and treatment. It will also be useful for medical workers in western countries where malaria is not as common. Considering that malaria causes morbidity and mortality, more especially among children below five years of age and pregnant mothers, it is therefore imperative that people from all walks of life should join hands to address this public health problem
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  • 76
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    ISBN: 9781789857627 , 9781789857610 , 9781839620782
    Sprache: Englisch
    Seiten: 1 Online-Ressource (68 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice. Its two major aims are to assist students who are preparing for clinical immunology examinations, and to help people who want to understand more about this subject with brief and flexible sources of information. This book presents current, medically important information on the rapidly changing field of tissue typing and its relation with diseases. It includes updated information on such topics as tissue typing in medicine and transplant immunology
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  • 77
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    ISBN: 9781789850185 , 9781789850178 , 9781838817688
    Sprache: Englisch
    Seiten: 1 Online-Ressource (82 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The cellular prion protein (PrPC) is expressed as a cell surface protein mainly in the central and peripheral nervous system. The discovery that prions are infectious agents changed the concept of protein synthesis in modern biology and built a bridge between the genesis of infectious and genetic diseases. This book discusses the normal function of the PrPC and its modulatory role in synaptic mechanisms. It describes the pathophysiological processes that accompany TSE - neurotoxicity, loss of anti-inflammatory protective function, neuronal death including prion-induced autophagy and apoptosis, and accumulation of PrPSc in the cytoplasm of neurons. Another aspect outlined here is that some prion diseases show strain variations that determine their development, demonstrating their key role in the development and progression of TSE
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  • 78
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    ISBN: 9781789849561 , 9781789849554 , 9781839620003
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (110 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Generally, in accordance with anatomical characteristics, urinary tract infections (UTIs) and in particular recurrent UTIs occur in women; in contrast, UTIs normally occur in men with different predisposing factors. There are several types of UTIs, including asymptomatic and symptomatic, complicated and uncomplicated, acute and chronic with a diversity of microbial pathogens. In pathogens, virulence factors and genes determine the type and severity of the UTIs. Obviously, UTIs are a huge problem in global public healthcare systems with a wide range of predisposing factors, including gender, microbial agent, the host's immune deficiencies, genetic diseases, catheterization, etc. The recent items determine the microbiology of UTIs. Accurate diagnosis and definitive treatment are the key to UTI reduction
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  • 79
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    ISBN: 9781789858228 , 9781789858211 , 9781838806378
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (148 p.)
    Serie: Infectious Diseases 2
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book gives a comprehensive overview of recent advances in human papillomavirus (HPV) infection, as well as general concepts of infections, immunopathology, diagnosis, treatment, epidemiology, and etiology. It examines current clinical recommendations in the management of HPV, highlighting the ongoing issues, recent advances, and future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of HPV, whose deep understanding is very important for safeguarding the human race from further loss of resources and economies due to HPV infection. I hope that this work will increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage
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  • 80
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    ISBN: 9781789857382 , 9781789857375 , 9781839620980
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (114 p.)
    Serie: Rheumatology 2
    Schlagwort(e): Immunology
    Kurzfassung: This book presents exclusive and comprehensive insight into the detailed molecular mechanisms of osteoarthritis (OA) initiation, progression and current advancements in the field. Inputs from clinician scientists, research and expertise offer a complete explanation of the current understanding of the pathogenesis of OA and practice in imaging and treatments strategies. Contributions from leading scientists provide a detailed introduction in the use of biomarkers in clinical research as well as in clinical practice and OA diagnosis. This book further discusses the potential of regenerative therapies and recent advances in cardiovascular and functional capacity on patients with OA
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  • 81
    ISBN: 9781789850000 , 9781789849998 , 9781838817619
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (180 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: For over 70 years, dengue fever has challenged health systems in every region of the World. It has evolved from a benign febrile illness from the tropics to a major concern in urban settlements, overwhelming health infrastructure with large outbreaks, as it continues to teach us important lessons with its complexities. This book intends to review the latest updates on dengue fever, the tools available for its study and control, and promising technologies currently in the pipeline. With this work, the editors wish to provide students with an updated reference text on the basics of this disease as well as researchers and academics, with a useful document to understand the current outlook and the perspectives for the future
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  • 82
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    ISBN: 9781789238044 , 9781789238037 , 9781838800468
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (108 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Vaccines is a well-written book on the subject of providing crucial information to students and researchers in the field of vaccinology. The introductory chapter, contributed by the editor (Dr. Vijay Kumar) of the book, provides the brief introduction to the history of the development of current forms of vaccine, which is difficult to find easily in one place. In addition, other chapters of the book are written by experts in the field. For example, the second chapter looks at the emerging role of developing countries in the innovation and production of vaccines. Other chapters provide information regarding different types of vaccines, development of vaccines for zoonotic viral infections, and regulatory affairs for genetically modified organism vaccines
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  • 83
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    ISBN: 9781838804695 , 9781838804688 , 9781838807610
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (150 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: This book aims to provide readers with some of the current trends in mycology. Its chapters include discussions on the major invasive fungal diseases, host-pathogen interactions, relationships between fungal growth and the environment, the use of fungal species to control soil parasites, and the antifungal properties of thiosulfonates. The information herein covers topics in mycological research and will be of interest to students and researchers in all biological sciences
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789850505 , 9781789850499 , 9781838817589
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (100 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges
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  • 85
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789851526 , 9781789851519 , 9781839621352
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (178 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Immune Response Activation and Immunomodulation has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. We have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology. The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion. Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book
    Anmerkung: English
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  • 86
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789848533 , 9781789848526 , 9781839621307
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (216 p.)
    Schlagwort(e): Immunology
    Kurzfassung: The mechanism of autoantibodies cannot be explained without the detail knowledge of cytokines and interferon. These active molecules of immunology are very much dependent on each other and their function cannot be completed without their interaction towards each other. Currently, this the most updated book on this subject that helps the readers/students to upgrade their knowledge by going through chapter by chapter. Contribution by the renounced authors across the globe makes this book really unique and consider as one of the most updated textbook on this subject. This book provides a comprehensive guide to the function and types of autoantibodies and cytokines in basic and clinical field
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  • 87
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789857665 , 9781789857658 , 9781839620812
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (182 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest
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  • 88
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789857689 , 9781789857672 , 9781839621468
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (142 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis
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  • 89
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781839622052 , 9781839622045 , 9781839622069
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (160 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Systemic sclerosis (scleroderma) is an incurable connective tissue disease of unknown etiology. Three key processes play a pivotal role in the pathogenesis: immune dysregulation and inflammation, endothelial injury and vasculopathy, and fibrosis. Tissue fibrosis is the dominant and characteristic feature that affects the skin and visceral organs. Life expectancy of scleroderma patients has improved over recent years, mainly because of better treatment of organ involvement and complications; however, no curative disease-modifying therapies exist to date. This book aims to provide students, trainees, rheumatologists, and other specialists interested in this disease with a comprehensive overview of novel pathogenetic mechanisms, management approaches, and therapeutic targets of several major vascular and fibrotic manifestations, and is useful insight into a number of usually neglected aspects of scleroderma
    Anmerkung: English
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  • 90
    Online-Ressource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789852868 , 9781789852851 , 9781839620058
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (98 p.)
    Schlagwort(e): Immunology
    Kurzfassung: This book highlights the numerous important properties of neutrophils and their role in various diseases, and as a possible therapeutic target as well. The first chapter briefly discusses the main effector neutrophil functions, which is followed by two chapters discussing the importance of different neutrophil receptors (cannabinoid and Fc?R) and their role in various disease conditions. The fourth chapter discusses the differential expression profile of CD16+CD11b+ on the surface of neutrophils as a tool for the diagnosis of acute infections. The last chapter discusses the physics of the NADPH oxidase system and the use of different chemiluminigenic probes for the detection of various reactive oxygen intermediates of the circulating neutrophils
    Anmerkung: English
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  • 91
    Online-Ressource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789852127 , 9781789852110 , 9781789854152
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (120 p.)
    Serie: Rheumatology 3
    Schlagwort(e): Immunology
    Kurzfassung: Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice
    Anmerkung: English
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  • 92
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789840124 , 9781789840117 , 9781789859201
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (128 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Infective endocarditis is a potentially life-threatening devastating disease. Due to its diagnostic difficulties, definite diagnosis may be delayed. Once diagnosed, the treatment options need careful judgment preferably among team members with specialization in cardiology, imaging, infectious disease, and thoracic surgery. The purpose of this book is to cover various aspects of the management of infectious endocarditis, which may serve as a basis of knowledge that will facilitate implementation of improved, evidenced-based care for this challenging disease
    Anmerkung: English
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  • 93
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789849875 , 9781789849868 , 9781838819989
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (170 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Hansen's Disease - The Forgotten and Neglected Disease provides concise information on the relevant aspects of the disease of leprosy, including immunological, epidemiological, clinical and molecular studies that are of great importance in the study of an often-ignored disease, which remains a great challenge to humanity. It collects contributions made by professional experts in the study of Mycobacterium leprae, providing perspectives with knowledge, experience and research, highlighting that the disease continues to be of interest to public health. It is expected that this book will be useful and contribute to the expansion of information and interest about the disease commonly known as leprosy
    Anmerkung: English
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  • 94
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789239027 , 9781789239010 , 9781838814823
    Sprache: Englisch
    Seiten: 1 Online-Ressource (102 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Rapid tests, also known as point-of-care tests, have been in use for decades in the clinical and medical area and have become increasingly popular as an efficient screening method for conducting on-site analysis thanks to their simplicity, speed, specificity and sensitivity. Nowadays, rapid tests are widely applied for clinical, drug, food, forensic and environmental analysis and fields of application are rapidly increasing together with advances in the technology. The growing interest in rapid tests and their expanding application in diverse fields, together with requirements of improved sensitivity, reliability, multiple detection capacity and robustness, are prompting innovation in the design of novel platforms, and in the exploitation of innovative detection strategies. The book covers advances in materials, technology and test design
    Anmerkung: English
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  • 95
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789844177 , 9781789844160 , 9781838817879
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (138 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes, and functions in different diseases. The following sections look closely at DC phenotyping, DC-NK cell interplay, and roles of DC in bone loss and repair and parasitic infections. The final section on DC and cancer includes perspectives on DC vaccination based on modifications and therapeutic applications
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  • 96
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789236996 , 9781789236989 , 9781838814236
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (112 p.)
    Schlagwort(e): Immunology
    Kurzfassung: "Vasculitis" describes an inflammatory process that involves the blood vessels and contributes to vascular damage. Autoimmunity, infections, drugs, and malignancies have been considered among potential etio-pathogenic factors. In vasculitis, the inflammation might develop in either a systemic or an organ-specific form and might exist as an independent pathology "primary vasculitis" or as a presentation of an existing primary pathology, that is, "secondary vasculitis". This book Vasculitis In Practice-An Update on Special Situations - Clinical and Therapeutic Considerations unlike many publications in the field, uses a different evidence-based approach to organ-specific vascular inflammatory diseases. The authors highlighted the unmet needs from the 1994 Chapel Hill Consensus Conference introducing the latest clinically relevant definitions for the different forms of vasculitis revised in 2012. The identification, classification, and management of kidney disease with different types of vasculitis with an evidence-based update on proposed therapeutic strategies are presented in this publication
    Anmerkung: English
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  • 97
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789235098 , 9781789235081 , 9781838815929
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (240 p.)
    Schlagwort(e): Immunology
    Kurzfassung: Immunotherapy is an innovative, leading and valuable approach to the treatment and control of many diseases. It can solve many problems of public health worldwide. Many people in numerous countries are suffering from a wide range of diseases (communicable and non-communicable) that can be cured or controlled by the immune system and immunotherapy. Some immunological diseases (i.e. allergic reactions and asthma, autoimmune disease, immunodeficiency disease, hypersensitivity reactions, etc.) have immune response pathophysiology and by controlling immune system mechanisms, these diseases can be controlled and cured. Immunoregulatory Aspects of Immunotherapy focuses on immune system mechanism, diagnosis, treatment and other related problems. The chapters have applicable and scientific data in immunotherapeutic approaches based on medical sciences, and would be of benefit to all researchers in immunology, allergy and asthma fields. The book discusses the prevention, diagnosis, treatment and follow-up of patients who have dangerous diseases. We hope this book will be a new approach to the immunotherapy of diseases and will improve public health and wellbeing
    Anmerkung: English
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  • 98
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789841022 , 9781789841015 , 9781838815219
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (232 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified
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  • 99
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789237825 , 9781789237818 , 9781838814281
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (200 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: Tuberculosis is an ancient disease with a high incidence and mortality rate, unequally distributed worldwide. Epidemiological indicators, but also risk factors, play a key role in the natural history of the disease and need to be regulary addressed. Low and middle income countries are not prepared for appropriate response and are also the most affected. The incidence of this extrapulmonary disease is far from being clearly established. Epidemiological studies in different geographical areas will help in this field
    Anmerkung: English
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  • 100
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9781789846034 , 9781789846027 , 9781838817107
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (258 p.)
    Schlagwort(e): Infectious & contagious diseases
    Kurzfassung: The HIV epidemic has had a significant and profound impact on the world and health resources. Considerable progress has been made in understanding the risks and drivers of the epidemic. Antiretroviral drugs have relieved human suffering and prolonged life. However, access to quality management needs to scale up and be made universal. This book discusses critical issues related to the treatment of HIV infection and related co-infections and challenges in adherence and discordancy. New vaccine approaches discussed may provide the ultimate solution for eradication. Sharing knowledge from various experts in medical and basic sciences improves the quality of care for this persistent global threat. This book discusses emerging advances in HIV-AIDS management to support strategies for control and elimination
    Anmerkung: English
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