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  • 2010-2014  (82)
  • 2005-2009
  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (82)
  • Endocrinology  (82)
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  • 1
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535113843 , 9789535172062
    Language: English
    Pages: 1 Online-Ressource (280 p.)
    Keywords: Endocrinology
    Abstract: The thyroid disorders are one of the most common and exciting areas of endocrinology. Hypothyroidism, multinodular goiter, hyperthyroidism and thyroid cancer are only few of the several implications that the thyroid disorders have in health. In fact, thyroid hormones regulate not only metabolism process, but also many other molecular and physiological systems. From this point of view, hyperthyroidism complications are a good example of the significance of thyroid hormone actions. This book aims to provide a general view of thyroid disorders, and a deeper explanation of hyperthyroidism and its complications and impact in health
    Note: English
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  • 2
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535112396 , 9789535172000
    Language: English
    Pages: 1 Online-Ressource (392 p.)
    Keywords: Endocrinology
    Abstract: Helicobacter pylori is a universally distributed bacterium which affects more than half of the world population. The infection is associated with the development of various diseases of the upper gastrointestinal tract, besides extradigestive diseases. This book is a comprehensive overview of contributors on H. pylori infection in several areas. Its chapters were divided into sections concerning general aspects of H. pylori infection, immunopathology and genetic diversity, questions regarding possible routes of bacterium transmission, the importance of the strains characteristics in the development of gastric cancer and the possibilities of prevention, H. pylori infection in children, the possible association between its infection and extradigestive diseases, and the principal therapeutic regimens of bacterium eradication, considering the antimicrobial resistance
    Note: English
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  • 3
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535112419 , 9789535172024
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Fecal incontinence is a common and disabling condition that unfortunately remains an “orphan” in terms of medical research and effective therapies. This book provides a brief review of the pathophysiology of fecal incontinence with specific focus on women and children. Authorship is drawn internationally, with a strong surgical input. Contributions from the authors provide critical reviews of the evaluation of function, with illustrations of a range of surgical interventions which might be applied should medical therapies fail
    Note: English
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  • 4
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535116189 , 9789535172123
    Language: English
    Pages: 1 Online-Ressource (176 p.)
    Keywords: Endocrinology
    Abstract: Most tissues and organs, such as the brain, need glucose constantly, as an important source of energy. The low blood concentrations of glucose (hypoglycemia) can cause seizures, loss of consciousness, and death. On the other hand, long lasting elevation of blood glucose concentrations (hyperglycemia) can result in blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Therefore, blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady-state level is called glucose homeostasis. This is accomplished by the finely hormone regulation of peripheral glucose uptake (glucose utilization), hepatic glucose production and glucose uptake during carbohydrates ingestion
    Note: English
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  • 5
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535112150 , 9789535171904
    Language: English
    Pages: 1 Online-Ressource (382 p.)
    Keywords: Endocrinology
    Abstract: The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases
    Note: English
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  • 6
    ISBN: 9789535116318 , 9789535172192
    Language: English
    Pages: 1 Online-Ressource (380 p.)
    Keywords: Endocrinology
    Abstract: The capsaicin, a component of paprika, has been used in the culinary practice of every day nutritional practice. This agent is known to cause a variety of actions in the body through activating capsaicin-sensitive afferent neurons. A recently launched book entitled, Capsaicin-Sensitive Neural Afferentation and the Gastrointestinal Tract: from Bench to Bedside, is attractive for several reasons. First, Prof. Mozsik, a chief editor of this book, is known internationally as an expert in capsaicin pharmacology. Since he has worked for many years as a head of internal medicine, taking care of patients with various GI diseases, he is able to make a correct interpretation of various findings obtained in basic researches to clinical events. Second, although there are many articles about capsaicin, they mostly deal with basic research and finding but do not include much about clinical finding. Third, this book encompassed review articles written by internationally accepted scientists leading the field of capsaicin research, who highlighted the current state of knowledge on pharmacology, physiology and clinical phathophysiology of capsaicin-sensitive afferent neurons, and discussed directions for future research. Overall, this book is for people who are interested in the capsaicin action in body
    Note: English
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  • 7
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535109075 , 9789535170631
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Endocrinology
    Abstract: Gastritis, as a medical term, exists for the last 150 years, however, terminology and etiology (including the prognosis ) has changed. Gastritis related medical problems are in the focus of different sub-disciplines: internists , gastroenterologists, pathologists, immunologists, bacteriologists, genetics, biologists etc. After the publications by Marshall and Warren most of the clinicians accepted only the etiopathological role of Helicobacter pylori in the development of gastric and duodenal ulcer , as well as in the gastric cancer. This book presents chapters abou the history of gastritis terminology, animal models, epidemiology, new gastric mucosal endogenous defensive neural mechanism (capsaicin-sinsitive afferentation), different research and clinical methods applied to the background studies and the molecular pathology, biochemistry and genetics involved in the pathways from Helicobacter pylori infection to development of gastric cancer. Intended audience of this book are internists, gastroenterologists, pathologists, bacteriologists, pharmacologists, genetics, biologists , immunologists and other interested researchers
    Note: English
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  • 8
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110774 , 9789535171348
    Language: English
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Endocrinology
    Abstract: This book summarizes several aspects of GD, which is caused by not well-understood multifactorial mechanisms. Common strategies seem to be key in the understanding of the syndrome, i.e., endothelial dysfunction and the role of other placenta cells such as trophoblasts. It is a book that will definitively help to increase the knowledge-based management of GD for the well being of the mother and the fetus. Several chapters lead us to the conclusion that pre-pregnancy and antenatal screening of women is required, something that will improve the management and outcome of a current pregnancy but will also optimize life-long health and well being considering the inter-generational consequences
    Note: English
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  • 9
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110170 , 9789535171027
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Endocrinology
    Abstract: This book contains a series of up-to-date chapters that review our current knowledge of type 1 diabetes as an autoimmune disease, the problems that still remain with existing treatments, and possible solutions for the near future
    Note: English
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  • 10
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535111115 , 9789535171423
    Language: English
    Pages: 1 Online-Ressource (104 p.)
    Keywords: Endocrinology
    Abstract: Recent Advances in the Field of Ventricular Assist Devices covers recent various advances and developments relating to ventricular assist devices and their diverse complications. Firstly, we overview recent technical advances as well as current indications, clinical outcomes, and countermeasures against complications, and furthermore, the latest techniques to identify clinical effectiveness at the patient’s bedside. Secondly, we elucidate the current status of countermeasures against gastrointestinal bleeding, and current research on allosensitization during the usage of continuous flow pump. Finally, we explore the possibility of a new adjunct therapy in combination with ventricular assist devices. We hope that this book will provide valuable and up-to-date information on research and clinical use of ventricular assist devices
    Note: English
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  • 11
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110811 , 9789535171263
    Language: English
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Endocrinology
    Abstract: An increase in aortic aneurysm occurrence is registered, despite considerable advances in surgical interventions. Consequently, numerous researchers have been trying to improve the understanding the aortic aneurysm pathogenesis in order to facilitate an early diagnosis, to identify new therapeutic targets, and to develop complex therapies. Within this book, the reader may find interesting data about etiology, risk factors, and pathogenesis of aortic aneurysm, its characteristics in young age, particularities of aneurysms affecting visceral arteries, the preoperative evaluation of the patients, different perspectives regarding the surgical therapy, including the treatment of complications after prior surgery, original proposals regarding new therapeutic modalities, and advanced imaging strategies. The multidisciplinary team of authors provides an interesting lecture and an update of the scientific literature
    Note: English
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  • 12
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535111719 , 9789535171676
    Language: English
    Pages: 1 Online-Ressource (546 p.)
    Keywords: Endocrinology
    Abstract: Type 2 diabetes is now a global serious health problem. Patients with type 2 diabetes have 2-4 times higher risk of cardiovascular and renal complications, morbidity and mortality. This book, Type 2 Diabetes, is a unique book covering the topics including pathophysiology, complications and prevention and treatments. Understanding the etiology of the onset and development of type 2 diabetes is important to prevent type 2 diabetes complications and delay the progress. The Pathophysiology section covers a wide range of mechanisms and characteristics from the micro (molecular) to the macro (neurohormonal mechanisms and the beta-cell function in the pancreas). The Complications section includes renal complications, sympathetic nervous system imbalance, atherosclerosis, and foot ulcers which are frequently observed in diabetic patients. Finally, the Prevention and Treatments section consists of non-pharmacological treatments, bariatric surgery, pharmacological therapy, and insulin therapy. The editor hopes that this book is helpful for your clinical practice and research, and this book facilitates the reduction of global burden of type 2 diabetes
    Note: English
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  • 13
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110064 , 9789535170938
    Language: English
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Endocrinology
    Abstract: This is a must-have book for those interested in reproduction. It provides a full account of our current knowledge of the hormones intimately associated with testicular and ovarian function. Each chapter is carefully organized to cover basic concepts and recent advances in gonadotropin synthesis and secretion. The information is presented in a sequence that provides researchers, teachers, and students with a logical integration of the reproductive axis. Practical applications associated with reproductive management of domestic species are also provided. Taken together, this book is a comprehensive combination of fundamental endocrine concepts and original findings in the area of gonadotropin function
    Note: English
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  • 14
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535109396 , 9789535170723
    Language: English
    Pages: 1 Online-Ressource (348 p.)
    Keywords: Endocrinology
    Abstract: The fundamental treatment and management goals in diabetes mellitus are to control and normalize blood glucose levels and to prevent diabetic complications. It also includes maintaining normal growth and development and normal body weight. Proper diet, regular exercise, weight control and different therapeutic agents are the mainstays of diabetic care and management. Weight reduction and exercise have been shown to improve tissue sensitivity to insulin and allow its proper use by target tissues. It is obvious that medical management and goals of therapy for diabetes mellitus have changed since the publication of the Diabetes Control and Complications Trial in 1993. Recent studies have shown that the risk of developing retinopathy can decrease by 76% in properly managed diabetic patients when compared to control group and that clinical and laboratory signs and symptoms of nephropathy and neuropathy can also decrease by 54 to 60%. Modern approaches to the management of diabetes mellitus embrace holistic options and this book addressed various approaches in the management of diabetes mellitus
    Note: English
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  • 15
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535112051 , 9789535171843
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Endocrinology
    Abstract: This textbook is specifically written for clinicians involved in managing patients with dyspepsia. It is a practical guide with up-to-date suggestions on evaluation, diagnosis, and management from experts from around the world. Each chapter is a succinct review of current topics that play a role in the pathogenesis and management of this disorder. Special populations such as pediatrics, those with cardiovascular disease and womens health are specifically examined
    Note: English
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  • 16
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110347 , 9789535171133
    Language: English
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Endocrinology
    Abstract: Endoscopy has had a major impact in the development of modern gastroenterology and other medical specialties. The field of endoscopic procedure has developed over the last decade. By using different data it provided a better understanding of pathogenic mechanisms, described new entities and used for early detection, diagnostic procedures and therapeutic procedures. The advantages of many technical advances and modern-endoscopic equipments, endoscopy has had a developed spectacularly. Furthermore, endoscopy has surpassed its function as an examination tool and it became a rapid and efficient therapeutic tool of low invasiveness. The efficacy and usefulness of endoscopy has yet been established
    Note: English
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  • 17
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535110804 , 9789535171386
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Endocrinology
    Abstract: This book covers a selected number of hot topics in endocrine and hormone-related pathologies, discussed by eminent scientists and clinicians coming from different countries of the world. It deals with advanced recent trends in the field, including neuroendocrine and pituitary tumors, thyroid dysfunctions, diabetes and a series of endocrine-related diseases, such as those related to the anabolic effects of testosterone, obesity, cancer, the liver complications of diabetes and the pediatric nonalcoholic fatty liver disease. The readers should be able to have a basic, as well as critic and advanced, overview of these selected hot pathologies of the endocrine system
    Note: English
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  • 18
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535109709 , 9789535170846
    Language: English
    Pages: 1 Online-Ressource (232 p.)
    Keywords: Endocrinology
    Abstract: Do you regard hypothyroidism as a more complex issue than just a simple prescription of levothyroxine tablet? Are you interested in getting more information on the management of thyroid dysfunction in pregnancy, at birth, in childhood or in subclinical states? Have you been thinking of performing thyroid ultrasound in hypothyroid patients by yourself, or perhaps you already do it and are not so sure about it? Than this book should give you some answers and help you form your own opinion. You will find there several excellent review articles from authors from all over the world
    Note: English
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  • 19
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535109440 , 9789535170747
    Language: English
    Pages: 1 Online-Ressource (474 p.)
    Keywords: Endocrinology
    Abstract: Lipids (fats and oils) are a wide range of organic molecules that serve several functions in organisms. Lipids are essential components of our diet, highlighting their important contribution in energy, representing 9 kcal/g (or 37.7 kJ/g), and by some components relevant to the metabolism, such as essential fatty acids, fat soluble vitamins and sterols (cholesterol and phytosterols). Besides this, lipids have key roles in human growth and development, along with promoting, preventing and/or participating in the origin or eventually in the treatment of various diseases. This book presents a systematic and comprehensive review about the structure and metabolism of lipids, particularly highlighting the importance of these molecules in the body and considering the interest of some lipids in health and disease
    Note: English
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  • 20
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535109143 , 9789535170679
    Language: English
    Pages: 1 Online-Ressource (306 p.)
    Keywords: Endocrinology
    Abstract: Gastric cancer is the second most common cause of cancer-related death in the world. There are no screening tests available for its diagnosis, therefore patients usually presents in late stages, associated with poor prognosis. Currently, many efforts are made toward new advances in the treatment strategies. The book makes an insight into the assessment of premalignant lesions, current management of early gastric cancer, risk and protective factors in gastric carcinogenesis. "Gastric cancer" provides a detailed description of the morphologic classification, molecular changes and epigenetic alterations of this tumor. The book describes the role of different diagnostic tools in the preoperative assessment of patients and the most important factors contributing to the prognosis. Moreover, it describes the current surgical and chemotherapeutic options for gastric neoplasm. This publication may open new and interesting gates for further research concerning carcinogenesis, genetic and epigenetic alterations, signaling pathways, H. pylori infection, the discovery of protective factors against gastric cancer and of revolutionary therapies of this tumor
    Note: English
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  • 21
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789533079844 , 9789535167792
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Endocrinology
    Abstract: Acute Pancreatitis (AP) in approximately 80% of cases, occurs as a secondary complication related to gallstone disease and alcohol misuse. However there are several other different causes that produce it such as metabolism, genetics, autoimmunity, post-ERCP, and trauma for example... This disease is commonly associated with the sudden onset of upper abdominal pain that is usually severe enough to warrant the patient seeking urgent medical attention. Overall, 10-25% of AP episodes are classified as severe. This leads to an associated mortality rate of 7-30% that has not changed in recent years. Treatment is conservative and generally performed by experienced teams often in ICUs. Although most cases of acute pancreatitis are uncomplicated and resolve spontaneously, the presence of complications has a significant prognostic importance. Necrosis, hemorrhage, and infection convey up to 25%, 50%, and 80% mortality, respectively. Other complications such as pseudocyst formation, pseudo-aneurysm formation, or venous thrombosis, increase morbidity and mortality to a lesser degree. The presence of pancreatic infection must be avoided
    Note: English
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  • 22
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535107408 , 9789535153184
    Language: English
    Pages: 1 Online-Ressource (178 p.)
    Keywords: Endocrinology
    Abstract: Understanding of the neuroendocrine system provides an insight into a wide range of bodily and mental processes. Neuroendocrinology and Behavior brings its readers a concise guide to up-to-date knowledge on the function of the endocrine glands and organs in association with neurotransmitters, neuropeptides, and behavioral manifestations. Various forms of stress response, e.g. anxiety and cognitive changes, have been intrinsic to both ourselves and other species. Specifically, these mechanisms involve complex interplays among physical, emotional, and behavioral processes in humans. This volume provides information on peptide hormones, i.e. oxytocin and vasopressin, and how studies of these neuropeptides enrich our understanding of social and other behaviors. These neuromodulators also affect sexual behavior and water balance in the body, an issue also addressed in this Book
    Note: English
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  • 23
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789533078915 , 9789535167532
    Language: English
    Pages: 1 Online-Ressource (346 p.)
    Keywords: Endocrinology
    Abstract: This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature
    Note: English
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  • 24
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535100201 , 9789535168010
    Language: English
    Pages: 1 Online-Ressource (268 p.)
    Keywords: Endocrinology
    Abstract: Hypothyroidism is the most common thyroid disorder. It can cause a variety of changes in women's menstrual periods, reduce their chances of becoming pregnant, as well as affect both the course of pregnancy and the neuropsychological development of babies. During pregnancy there is a substantially increased need for thyroid hormones and a substantial risk that a previously unnoticed, subclinical or latent hypothyroidism will turn into overt hypothyroidism. The thyroid inflammation caused by the patient's own immune system may form autoimmune thyroiditis (Hashimoto's thyroiditis). Congenital hypothyroidism (CH) occurs in approximately 1:2,000 to 1:4,000 newborns. Nearly all of the developed world countries currently practice newborn screening to detect and treat congenital hypothyroidism in the first weeks of life. "A New Look at Hypothyroidism" contains many important specifications and innovations for endocrine practice
    Note: English
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  • 25
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535106845 , 9789535170143
    Language: English
    Pages: 1 Online-Ressource (198 p.)
    Keywords: Endocrinology
    Abstract: Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye and barley) in genetically susceptible individuals. CD can manifest itself with a previously unappreciated range of clinical presentations, including the typical malabsorption syndrome and a spectrum of symptoms potentially affecting any organ system. Since CD often presents in an atypical or even silent manner, many cases remain undiagnosed and carry the risk of long-term complications, including anemia and other hematological complications, osteoporosis, neurological complications or cancer. The high prevalence of the disease and its variety of clinical outcomes raise several interesting questions. This book covers most of the aforementioned controversial and yet unresolved topics by including the contributions of experts in CD.What the reader will surely find stimulating about this book is not only its exhaustive coverage of our current knowledge of CD, but also provocative new concepts in disease pathogenesis and treatment
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  • 26
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535104193 , 9789535169383
    Language: English
    Pages: 1 Online-Ressource (94 p.)
    Keywords: Endocrinology
    Abstract: Microangiopathies are pathological processes causing degenerative disorders of small vessels. The circulatory problems caused by microangiopathies may be responsible for failure of individual or multiple organs. These pathological processes are indeed one of the most common disorders characterized by high morbility and mortality in the affected patients. Many studies have revealed very complicated processes both at cellular and molecular level. However, much work remains to define the diversity of different pathogenetic mechanisms leading to microangiopathic disorders to provide appropriate prevention and treatment strategies. The aim of this volume is providing illustrative examples of relevant mechanisms responsible for different forms of microangiopathies and how this body of evidences can be harnessed to define new strategies of therapeutic intervention
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  • 27
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535108795 , 9789535170471
    Language: English
    Pages: 1 Online-Ressource (292 p.)
    Keywords: Endocrinology
    Abstract: This book is an overview of invited contributions on recent data of inflammatory bowel diseases. The first part of the book covers topics related to the ethiopathogenesis of inflammatory bowel diseases including the environmental, genetic factors and immunological alternations. The next chapters deal with present day management of disease including radiological diagnosis and surgical treatment, which consider the advances of most up-to-date radiological methodology including MRI techniques and the role of surgical procedures in the therapy. The final part presents medical therapy and its future directions. These chapters discuss natural products exerting anti-inflammatory and anti-tumour effects, methods of colon targeting drug delivery systems including polysaccharides, peptides and nanoparticules; as well as the potential risks of nanotechnology based food materials
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  • 28
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535106784 , 9789535170181
    Language: English
    Pages: 1 Online-Ressource (398 p.)
    Keywords: Endocrinology
    Abstract: Thyroid hormone is important for controlling metabolism and many other body functions. Changes in thyroid hormone physiology, its regulation and diseases thereof have been a concern for the mankind. Understanding of the thyroid hormone(s) has been continuously updated and revised. The contributions from different authors have been incorporated in this book for this purpose. The original work of these contributors will be especially useful in furthering the knowledge on thyroid and help in creating new vistas of research
    Note: English
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  • 29
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535108917 , 9789535170518
    Language: English
    Pages: 1 Online-Ressource (256 p.)
    Keywords: Endocrinology
    Abstract: The progression from normal glucose tolerance (NGT) to type 2 diabetes involves intermediate stages of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), also known as prediabetes. The pathophysiology underlying the development of these glucose metabolic alterations is multifactorial, leading to an alteration in the balance between insulin sensitivity and insulin secretion. Our knowledge of the molecular basis of the signaling pathways mediating the various physiologic effects of insulin is steadily advancing. New substrates and signaling molecules have been identified and potential mechanisms involved in the pathophysiology of type 2 diabetes have been revealed. This book summarises the current state of knowledge on the pathophysiology underlying the progression from normal glucose tolerance to type 2 diabetes and therapeutic advances in the improvement of glycaemic control in prediabetic and diabetic states
    Note: English
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  • 30
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535108900 , 9789535170501
    Language: English
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Endocrinology
    Abstract: This book has been made possible by the contributions of leading scientists and clinicians from upcoming and interdisciplinary fields of research concerning the molecular and clinical features of insulin resistance. Multiple metabolic disturbances associated with Insulin Resistance include inflammatory cytokines, adipokines, endothelial dysfunction, tissue-specific defects in insulin action and signaling, oxidative stress, ectopic lipid deposition, and disordered neuroregulation. This book aims to encourage scientists and physicians - working separately on various aspects of Insulin resistance and metabolic syndrome for early detection of the first signs indicating the onset of a metabolic misbalance in order to prevent the consecutive cascades which lead to metabolic syndrome, resulting in the so-called diseases of modern civilization - cancer, diabetes and hypertension
    Note: English
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  • 31
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535102212 , 9789535168690
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Endocrinology
    Abstract: This book was designed to meet the requirements of all who wish to acquire profound knowledge of basic, clinical, psychiatric and laboratory concepts as well as surgical techniques regarding thyroid and parathyroid glands. It was divided into three main sections: 1. Evaluating the Thyroid Gland and its Diseases includes basic and clinical information on the most novel and quivering issues in the area. 2. Psychiatric Disturbances Associated to Thyroid Diseases addresses common psychiatric disturbances commonly encountered in the clinical practice. 3. Treatment of Thyroid and Parathyroid Diseases discusses the management of thyroid and parathyroid diseases including new technologies
    Note: English
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  • 32
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535101628 , 9789535152125
    Language: English
    Pages: 1 Online-Ressource (228 p.)
    Keywords: Endocrinology
    Abstract: Description of hydrocephalus can be found in ancient medical literature from Egypt as old as 500 AD. Hydrocephalus is characterized by abnormal accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. This results in the rise of intracranial pressure inside the skull causing progressive increase in the size of the head, seizure, tunneling of vision, and mental disability. The clinical presentation of hydrocephalus varies with age of onset and chronicity of the underlying disease process. Acute dilatation of the ventricular system manifests with features of raised intracranial pressure while chronic dilatation has a more insidious onset presenting as Adams triad. Treatment is generally surgical by creating various types of cerebral shunts. Role of endoscopic has emerged lately in the management of hydrocephalus
    Note: English
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  • 33
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535103141 , 9789535169079
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Gastroesophageal reflux disease affects many patients. This disease not only lowers their quality of life, but it also threatens some of them with an underhand risk of cancer. Additionally, it becomes an economic burden for the patients and society. The aim of this book on gastroesophageal reflux disease is to provide advice and guidance to gastroenterologists to help them understand and manage some aspects of this proteiform disease
    Note: English
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  • 34
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535100003 , 9789535167891
    Language: English
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Endocrinology
    Abstract: We are truly in an era of change not only in terms of technology but in the type of patient we are caring for. That is why I feel this book is exciting in that it presents the team approach to the transplant patient. I am confident that the pioneers of cardiac transplantation would be pleased with our response to challenges in healthcare today and be pleased with the final product
    Note: English
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  • 35
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789533078113 , 9789535166306
    Language: English
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Endocrinology
    Abstract: In this book, several important points regarding Crohn's disease are discussed. In the first section, we focus on etiopathogeny of Crohn's disease and the recent advances in our overall understanding of the disease - specifically, the role of the gut epithelium, alterations of the epithelial crypts, and the roles of the different cytokines in the pathophysiology of Crohn's disease. In the second section, a diagnosis of Crohn's disease is discussed. Another particular area of focus is in the diagnosis of intestinal tuberculosis, and the role of mycobacterium avium in Crohn's disease. In the third and final section, the management of Crohn's disease is discussed, with a focus on recent evidence-based medicine recommendations
    Note: English
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  • 36
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789533078144 , 9789535166283
    Language: English
    Pages: 1 Online-Ressource (238 p.)
    Keywords: Endocrinology
    Abstract: This book is a collection of essays and papers from around the world, written by surgeons who look after patients of all ages with abdominal pain, many of whom have appendicitis. All general surgeons maintain a fascination with this important condition because it is so common and yet so easy to miss. All surgeons have a view on the literature and any gathering of surgeons embraces a spectrum of opinion on management options. Many aspects of the disease and its presentation and management remain controversial. This book does not answer those controversies, but should prove food for thought. The reflections of these surgeons are presented in many cases with novel data. The chapters encourage us to consider new epidemiological views and explore clinical scoring systems and the literature on imaging. Appendicitis is discussed in patients of all ages and in all manner of presentations
    Note: English
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  • 37
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535108535 , 9789535170440
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Endocrinology
    Abstract: Liver biopsy is a procedure that involves obtaining a small piece of liver tissue, which is then analyzed in the laboratory. Liver biopsy may be used to evaluate a mass seen on images, diagnose unexplained liver diseases or abnormal liver function tests, and to determine the severity of the liver disease including hepatitis, fibrosis, and steatosis. Liver biopsy is an invasive procedure, and its complications are rare but potentially lethal. Therefore, it is necessary to perform liver biopsy safely from clinical aspect and to take specimen steadily from a pathological one. I hope this book addresses the future aspects of liver biopsy including role, indication, technique and evaluation. Furthermore, this book introduces new non-invasive alternatives including elastography and computer analysis of liver fibrosis
    Note: English
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  • 38
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535108726 , 9789535170464
    Language: English
    Pages: 1 Online-Ressource (660 p.)
    Keywords: Endocrinology
    Abstract: As one class of the most important steroid hormones, glucocorticoids have long been recognised and their therapeutic benefits have been widely used in clinical treatment, especially in anti-inflammation cases. Glucocorticoids regulate various processes in the body including the mobilization of energy stores, immune functions, gene expression, and maintenance of the homeostasis as well as the stress response, this is not surprising that the concept of "glucocorticoids" is mentioned in almost all medical text books that focus on specific organs or systems such as the cardiovascular system, the immune system, and the neuroendocrine system. The book of Glucocorticoids - New Recognition of Our Familiar Friend aims to introduce the latest findings relating to glucocorticoids, either freshly from the laboratory or from clinical case studies, and to open up a new angle of looking at the issue of balancing the therapeutic benefits and side effects brought up by glucocorticoids
    Note: English
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  • 39
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535105213 , 9789535169666
    Language: English
    Pages: 1 Online-Ressource (568 p.)
    Keywords: Endocrinology
    Abstract: The purpose of this book was to present the integrative, basic and clinical approaches based on recent developments in the field of gastroenterology. The most important advances in the pathophysiology and treatment of gastrointestinal disorders are discussed including; gastroesophageal reflux disease (GERD), peptic ulcer disease, irritable bowel disease (IBD), NSAIDs-induced gastroenteropathy and pancreatitis. Special focus was addressed to microbial aspects in the gut including recent achievements in the understanding of function of probiotic bacteria, their interaction with gastrointestinal epithelium and usefulness in the treatment of human disorders. We hope that this book will provide relevant new information useful to clinicians and basic scientists as well as to medical students, all looking for new advancements in the field of gastroenterology
    Note: English
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  • 40
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535100218 , 9789535168027
    Language: English
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Endocrinology
    Abstract: Hypothyroidism is the most common thyroid disorder and it is significantly more frequent than presented - millions of people suffer from this disease without knowing it. People with this condition will have symptoms associated with slow metabolism. Estimates of subclinical hypothyroidism range between 3 to 8 %, increasing with age, whereas it more likely affects women than men. About 10% of women may have some degree of thyroid hormone deficiency. Hypothyroidism may affect lipid metabolism, neurological diseases or other clinical conditions. The book includes studies on advancements in diagnosis, regulation and replacement therapy, thyroid ultrasonography and radioiodine therapy for hypothyroidism. "Hypothyroidism - Influences and Treatments" contains many important specifications, results of scientific studies and innovations for endocrine practice
    Note: English
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  • 41
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    ISBN: 9789533078663 , 9789535167341
    Language: English
    Pages: 1 Online-Ressource (246 p.)
    Keywords: Endocrinology
    Abstract: This book explains the basic science of steroids and is targeted towards professionals engaged in health services. It should be noted that medical science evolves rapidly and some information like the understanding of steroids and their therapeutic use may change with new concepts quickly. Steroids are either naturally occurring or synthetic fat-soluble organic compounds. They are found in plants, animals, and fungi. They mediate a very diverse set of biological responses. The most widespread steroid in the body is cholesterol, an essential component of cell membranes, and the starting point for the synthesis of other steroids. Since the science of steroids has an enormous scope, we decided to put the clinical aspects of steroids in a different book titled "Steroids-Clinical Aspects". The two books complete each other. We hope that the reader will gain valuable information from both books and enrich their knowledge about this fascinating topic
    Note: English
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  • 42
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    ISBN: 9789535102519 , 9789535168843
    Language: English
    Pages: 1 Online-Ressource (158 p.)
    Keywords: Endocrinology
    Abstract: Portal hypertension is a clinical syndrome defined by a portal venous pressure gradient, exceeding 5 mm Hg. In this book the causes of its development and complications are described. Authors have presented personal experiences on conducting patients with various displays of portal hypertension. Moreover, the book presents modern data about molecular mechanisms of pathogenesis of portal hypertension in liver cirrhosis, the information about the original predictor of risk of bleeding from gastro-esophageal varices and new methods for their conservative treatment
    Note: English
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  • 43
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    ISBN: 9789535107729 , 9789535170310
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Endocrinology
    Abstract: During the last two decades, evidence of increasing trends of several endocrine-related disorders has been strengthened. These disorders often come with lack of uniform diagnosis and/ or even unclear endocrine disruption. The later is mainly due to abnormal classical changes in the blood- released hormone to its targeted organ, abnormal communication between cells within a tissue or organ (paracrine), within the same cell (intracrine) or signals which act on the same cell (autocrine). This challenging status drives endocrinologists to the urgent need to address enormous knowledge gaps in this wide field of research (Endocrinology). From the perspective point of view that "hormones control our bodies", we need to get these hormones rebalanced so we can restore overall health. That is simply endocrinology!
    Note: English
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  • 44
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535105312 , 9789535169710
    Language: English
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Endocrinology
    Abstract: Atrial Septal Defects (ASDs) are relatively common both in children and adults. Recent reports of increase in the prevalence of ASD may be related use of color Doppler echocardiography. The etiology of the ASD is largely unknown. While the majority of the book addresses closure of ASDs, one chapter in particular focuses on creating atrial defects in the fetus with hypoplastic left heart syndrome. This book, I hope, will give the needed knowledge to the physician caring for infants, children, adults and elderly with ASD which may help them provide best possible care for their patients
    Note: English
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  • 45
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    ISBN: 9789535101093 , 9789535168317
    Language: English
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Endocrinology
    Abstract: Pancreatitis may be acute or chronic. Although they can be caused by similar aetiologies, they tend to follow distinct natural histories. Around 80% of acute pancreatitis (AP) diagnoses occur as secondary to gallstone disease and alcohol misuse. This disease is commonly associated with the sudden onset of upper abdominal that is usually severe enough to warrant the patient seeking urgent medical attention. Overall, 10 to 25% of AP episodes are classified as severe, leading to an associated mortality rate of 7 to 30%. Treatment is conservative and consists of general medical support performed by experienced teams, sometimes in ICUs. Although most cases of acute pancreatitis are uncomplicated and resolve spontaneously, the presence of complications has significant prognostic importance. Necrosis, hemorrhage, and infection convey rates of up to 25%, 50%, and 80% mortality, respectively. Other complications such as pseudocyst formation, pseudoaneurysm formation, or venous thrombosis increase morbidity and mortality to a lesser degree. The presence of pancreatic infection must be avoided
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  • 46
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535100430 , 9789535168164
    Language: English
    Pages: 1 Online-Ressource (108 p.)
    Keywords: Endocrinology
    Abstract: This book covers different aspects on the understanding of mechanisms, effects, and management of cholestasis. This unique compendium contains important citations, an invaluable amount of research work, and many applications, which are outstanding resources for clinicians, pharmacists, biochemists, upper-level undergraduate, graduate, and continuing-education students who are dedicated to discovering new knowledge on cholestasis
    Note: English
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  • 47
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    ISBN: 9789535100416 , 9789535168157
    Language: English
    Pages: 1 Online-Ressource (98 p.)
    Keywords: Endocrinology
    Abstract: Pituitary Adenomas is a comprehensive book about the most common pathology of the pituitary gland in the sellar region. The book chapters include epidemiology, symptoms and signs, clinical, imaging, immunohistochemical and ultrastructural pathological diagnosis, therapeutic approaches and outcome of the functional and non-functional pituitary tumors. Therapies include medications, endoscopic transphenoidal and open surgeries; radiotherapy includes gamma knife radiosurgery. Visual symptoms has important and characteristic patterns which has discussed in one specific chapter. Endocrine secretion is another characteristic in 40% of pituitary adenomas. Therefore, another chapter presents it. Stereotactic radiosurgery and endoscopic surgery both have special role in recent decades. Thus, they have considered specifically, too. Authors expect to give excellent insight in pituitary adenoma to the book readers
    Note: English
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  • 48
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    ISBN: 9789535108573 , 9789535170457
    Language: English
    Pages: 1 Online-Ressource (222 p.)
    Keywords: Endocrinology
    Abstract: Steroids - From Physiology to Clinical Medicine covers contemporary basic science on steroids research, along with steroids practical application in clinical medicine. We start by describing physiological and pathophysiological roles of steroids, with reference to production and action of gonadal steroids, role of steroid sulfonation, sex specific and steroids-dependent mechanism of hippocampal function, and the hydroxysteroid dehydrogenases for the modulation of tissue glucocorticoid availability. We then covered different aspects of steroids application in clinical environment, such as endocrine function after ovarian transplantation, diagnostic significance of salivary assessment of androgens, drawbacks of steroids use in sport, analysis of serum steroid hormone profiles in patients with adrenocortical tumors, and correlation between salivary and serum cortisol responses after alcohol intake. In response to the need to address novel and valuable information on steroids science and medicine, we sincerely hope that this book will enable readers to comprehend this fast-growing and exciting scientific discipline
    Note: English
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  • 49
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    ISBN: 9789535104780 , 9789535169543
    Language: English
    Pages: 1 Online-Ressource (106 p.)
    Keywords: Endocrinology
    Abstract: This book is the result of the collaboration between worldwide authorities of different specialities in hyperparathyroidism. It aims to provide a general but deep view of primary/secondary and tertiary hyperparathyroidism, from a physiological basis to hyperparathyroidism in hemodialyzed patients, as well as new treatment approaches, techniques and surgical scenarios. We hope that the medical and paramedical researchers will find this book helpful and stimulating. We look forward to sharing knowledge of hyperparathyroidism with a wider audience
    Note: English
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  • 50
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    ISBN: 9789533079851 , 9789535167808
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Endocrinology
    Abstract: Alcoholic liver disease occurs after prolonged heavy drinking. Not everyone who drinks alcohol in excess develops serious forms of alcoholic liver disease. It is likely that genetic factors determine this individual susceptibility, and a family history of chronic liver disease may indicate a higher risk. Other factors include being overweight and iron overload. This book presents state-of-the-art information summarizing the current understanding of a range of alcoholic liver diseases. It is hoped that the target readers - hepatologists, clinicians, researchers and academicians - will be afforded new ideas and exposed to subjects well beyond their own scientific disciplines. Additionally, students and those who wish to increase their knowledge will find this book a valuable source of information
    Note: English
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  • 51
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    ISBN: 9789535102373 , 9789535168799
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Constipation is common in both adults and children. Estimates would suggest a median prevalence of around 12-16% in the general population. While regarded as a minor nuisance in some cases, its consequences can be severe, with a substantial impact on quality of life. Secondary faecal soiling has a profound psychological effect at all ages. This book provides contributions from authors with a range of backgrounds which clarify the pathogenesis, diagnosis, and therapy of constipation for the general population and also for certain high risk groups
    Note: English
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  • 52
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    ISBN: 9789533079042 , 9789535167594
    Language: English
    Pages: 1 Online-Ressource (482 p.)
    Keywords: Endocrinology
    Abstract: Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment
    Note: English
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  • 53
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    ISBN: 9789533078533 , 9789535167235
    Language: English
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Endocrinology
    Abstract: Ulcerative Colitis (UC) is a rapidly evolving medical field, and will continue to be very exiting in the next few decades. Although the underlying cause of this disease is still unknown, results in research dealing with various issues related to this disease are published every day. Chapters included in this book review the most recent literature on related advancements in regard to this chronic disease, which is controllable but not curable. Aspects like epidemiology, pathophysiology, genetics, incriminated etiologies, clinical aspects, complications, and disease management, including advancements in the diagnostic and therapeutic options, were documented by well known clinicians, researchers, and world wide authorities in their fields. This book on UC will be a valuable addition to each doctor's library interested in this subject, or for physicians dealing with patients suffering from this disease. Authors have also included figures and diagrams to depict their point, and to easily reach the minds of the readers in the simplest way
    Note: English
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  • 54
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    ISBN: 9789535100119 , 9789535167976
    Language: English
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Endocrinology
    Abstract: Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted
    Note: English
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  • 55
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    [Erscheinungsort nicht ermittelbar] : IntechOpen | Rijeka : IntechOpen
    ISBN: 9789535167563
    Language: English
    Pages: 1 Online-Ressource (152 Seiten) , Illustrationen (teilweise farbig), Tabellen
    Edition: First published
    Keywords: Endocrinology
    Abstract: Endocarditis is a disease that occurs as a result of the inflammation of the endocardium. It is an inflammatory process located in the inner lining of the cardiac chambers and native or prosthetic valves. It is characterized by colonization or invasion of the heart valve vegetations composed of platelets forming, fibrin and microcolonies of microorganisms, and occasionally of inflammatory cells. Other structures may also be affected, such as the interventricular septum, chordae tendineae, the mural endocardium or even intra-cardiac implants. The book covers, with scientific rigour, the most prevalent causes and current treatments of endocarditis, as well as the cases when the organs remote from the heart are affected by this disease
    Note: Literaturangaben
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  • 56
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    ISBN: 9789535108337 , 9789535170402
    Language: English
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Endocrinology
    Abstract: Diabetes mellitus is a complex, progressive disease, which is accompanied by multiple complications. It is a metabolic disorder of the endocrine system and listed among the most common disorders in both developed and developing countries. It has a global metabolic epidemic and it is estimated that the number of people affected by the disease will rise from the current 150 to 230 million by 2025. Hyperglycaemia is a characteristic feature of diabetes mellitus and chronic hyperglycaemia could lead to long-term complications in the eyes, kidneys, nerves, heart and blood vessels. Interestingly, this book examines the pathophysiology and selected complications in diabetes mellitus
    Note: English
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  • 57
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    ISBN: 9789533077567 , 9789535165781
    Language: English
    Pages: 1 Online-Ressource (484 p.)
    Keywords: Endocrinology
    Abstract: This book is intended as an overview of recent progress in type 1 diabetes research worldwide, with a focus on different research areas relevant to this disease. These include: diabetes mellitus and complications, psychological aspects of diabetes, perspectives of diabetes pathogenesis, identification and monitoring of diabetes mellitus, and alternative treatments for diabetes. In preparing this book, leading investigators from several countries in these five different categories were invited to contribute a chapter to this book. We have striven for a coherent presentation of concepts based on experiments and observation from the authors own research and from existing published reports. Therefore, the materials presented in this book are expected to be up to date in each research area. While there is no doubt that this book may have omitted some important findings in diabetes field, we hope the information included in this book will be useful for both basic science and clinical investigators. We also hope that diabetes patients and their family will benefit from reading the chapters in this book
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  • 58
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    ISBN: 9789533076287 , 9789535165002
    Language: English
    Pages: 1 Online-Ressource (158 p.)
    Keywords: Endocrinology
    Abstract: Currently, aortic stenosis is the most frequent heart valve disease in developed countries and its prevalence increases with the aging of the population. Affecting 3-5 percent of persons older than 65 years of age, it makes a large personal and economical impact. The increasing number of elderly patients with aortic stenosis brings advances in all medical specialties dealing with this clinical entity. Patients previously considered too old or ill are now indicated for aortic valve replacement procedures. This book tries to cover current issues of aortic valve stenosis management with stress on new trends in diagnostics and treatment
    Note: English
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  • 59
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    ISBN: 9789533073620 , 9789535165859
    Language: English
    Pages: 1 Online-Ressource (672 p.)
    Keywords: Endocrinology
    Abstract: This book is a compilation of reviews about the pathogenesis of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes. Areas including T cell development, innate immune responses, imaging of pancreata, potential viral initiators, etc. are considered
    Note: English
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  • 60
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789533077437 , 9789535164944
    Language: English
    Pages: 1 Online-Ressource (230 p.)
    Keywords: Endocrinology
    Abstract: Endoscopy has had a big role in the development of modern gastroenterology. Modern endoscopy will certainly be more therapeutic. It started with endoscopic hemostasis and polipectomy, than beginning of the 1970's with the advent of endoscopic sphincterotomy extended to biliopancreatic pathology and has a huge impact in this difficult pathology. Plastic stents made the first steps in endoscopic palliation of neoplastic jaundice, metallic stents, covered or uncovered are better for biliary palliation and can be used also for palliation neoplastic obstruction at different levels of the digestive tube. Resection of digestive tumors has evolved now to sub-mucosal resection, looking to have one-piece complete resection. Interventional endoscopy is now very complex and takes a lot of time for endoscopists to learn properly these techniques. This book is a very good up-to-date overview of new techniques of interventional endoscopy for those who want to learn or develop their knowledges in this field
    Note: English
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  • 61
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    ISBN: 9789533073576 , 9789535165934
    Language: English
    Pages: 1 Online-Ressource (480 p.)
    Keywords: Endocrinology
    Abstract: This book aims to provide readers with a general as well as an advanced overview of the key trends in endocrine disorders. While covering a variety of topics ranging from thyroid carcinogenesis and pituitary adenomas to adrenal tumors and metabolic bone disease, this book also focuses on more specific issues not yet fully elucidated (e.g. the molecular pathways involved in thyrotropin beta gene regulation or monogenic phosphate balance disorders). Readers of different fields and background will have the opportunity to update their knowledge and more importantly to clarify areas of uncertainty and controversies in several topics of endocrine disorders
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    ISBN: 9789533077772 , 9789535165095
    Language: English
    Pages: 1 Online-Ressource (324 p.)
    Keywords: Endocrinology
    Abstract: As result of progress, endoscopy has became more complex, using more sophisticated devices and has claimed a special form. In this moment, the gastroenterologist performing endoscopy has to be an expert in macroscopic view of the lesions in the gut, with good skills for using standard endoscopes, with good experience in ultrasound (for performing endoscopic ultrasound), with pathology experience for confocal examination. It is compulsory to get experience and to have patience and attention for the follow-up of thousands of images transmitted during capsule endoscopy or to have knowledge in physics necessary for autofluorescence imaging endoscopy. Therefore, the idea of an endoscopist has changed. Examinations mentioned need a special formation, a superior level of instruction, accessible to those who have already gained enough experience in basic diagnostic endoscopy. This is the reason for what these new issues of endoscopy are presented in this book of New techniques in Gastrointestinal Endoscopy
    Note: English
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  • 63
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    ISBN: 9789533076522 , 9789535165606
    Language: English
    Pages: 1 Online-Ressource (362 p.)
    Keywords: Endocrinology
    Abstract: Over the last few decades the prevalence of diabetes has dramatically grown in most regions of the world. In 2010, 285 million people were diagnosed with diabetes and it is estimated that the number will increase to 438 million in 2030. Hypoglycemia is a disorder where the glucose serum concentration is usually low. The organism usually keeps the serum glucose concentration in a range of 70 to 110 mL/dL of blood. In hypoglycemia the glucose concentration normally remains lower than 50 mL/dL of blood. Hopefully, this book will be of help to many scientists, doctors, pharmacists, chemicals, and other experts in a variety of disciplines, both academic and industrial. In addition to supporting researcher and development, this book should be suitable for teaching
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  • 64
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    ISBN: 9789533073750 , 9789535164838
    Language: English
    Pages: 1 Online-Ressource (310 p.)
    Keywords: Endocrinology
    Abstract: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression
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  • 65
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    ISBN: 9789533078809 , 9789535167457
    Language: English
    Pages: 1 Online-Ressource (294 p.)
    Keywords: Endocrinology
    Abstract: This book is intended to act as an up-to-date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular, Ulcerative Colitis. All authors of the chapters are experts in their fields of publication, and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating, and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine
    Note: English
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  • 66
    ISBN: 9789533075976 , 9789535164593
    Language: English
    Pages: 1 Online-Ressource (456 p.)
    Keywords: Endocrinology
    Abstract: Type 2 diabetes "mellitus" affects nearly 120 million persons worldwide- and according to the World Health Organization this number is expected to double by the year 2030. Owing to a rapidly increasing disease prevalence, the medical, social and economic burdens associated with the microvascular and macrovascular complications of type 2 diabetes are likely to increase dramatically in the coming decades. In this volume, leading contributors to the field review the pathogenesis, treatment and management of type 2 diabetes and its complications. They provide invaluable insight and share their discoveries about potentially important new techniques for the diagnosis, treatment and prevention of diabetic complications
    Note: English
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  • 67
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    ISBN: 9789533077277 , 9789535166023
    Language: English
    Pages: 1 Online-Ressource (290 p.)
    Keywords: Endocrinology
    Abstract: Over the last decade, it is becoming increasingly clear that diabetes mellitus is a global epidemic. The influence of diabetes is most readily apparent in its manifestation in foot complications across cultures and continents. In this unique collaboration of global specialists, we examine the explosion of foot disease in locations that must quickly grapple with both mobilizing medical expertise and shaping public policy to best prevent and treat these serious complications. In other areas of the world where diabetic foot complications have unfortunately been all too common, diagnostic testing and advanced treatments have been developed in response. The bulk of this book is devoted to examining the newest developments in basic and clinical research on the diabetic foot. It is hoped that as our understanding of the pathophysiologic process expands, the devastating impact of diabetic foot complications can be minimized on a global scale
    Note: English
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  • 68
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    ISBN: 9789533075907 , 9789535165521
    Language: English
    Pages: 1 Online-Ressource (354 p.)
    Keywords: Endocrinology
    Abstract: Type 2 diabetes is estimated to affect 120 million people worldwide- and according to projections from the World Health Organization this number is expected to double over the next two decades. Novel, cost-effective strategies are needed to reverse the global epidemic of obesity which is driving the increased occurrence of type 2 diabetes and to less the burden of diabetic vascular complications. In the current volume, Topics in the Prevention, Treatment and Complications of Type 2 Diabetes, experts in biology and medicine from four different continents contribute important information and cutting-edge scientific knowledge on a variety of topics relevant to the management and prevention of diabetes and related illnesses
    Note: English
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  • 69
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    ISBN: 9789533073859 , 9789535165774
    Language: English
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Endocrinology
    Abstract: Endoscopy has had a major impact in the development of modern gastroenterology. By using different data it provided a better understanding of pathogenic mechanisms, described new entities and changed diagnostic and therapeutic strategies. Meanwhile, taking advantage of many technical advances, endoscopy has had a developed spectacularly. Video-endoscopes, magnification, confocal and narrow-band imaging endoscopes, endoscopic ultrasounds and enteroscopes emerged. Moreover, endoscopy has surpassed its function as an examination tool and it became a rapid and efficient therapeutic tool of low invasiveness. InTech Open Access Publisher selected several known names from all continents and countries with different levels of development. Multiple specific points of view, with respect to different origins of the authors were presented together with various topics regarding diagnostic or therapeutic endoscopy. This book represents a valuable tool for formation and continuous medical education in endoscopy considering the performances or technical possibilities in different parts of the world
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  • 70
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    ISBN: 9789533073637 , 9789535164791
    Language: English
    Pages: 1 Online-Ressource (424 p.)
    Keywords: Endocrinology
    Abstract: Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes
    Note: English
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  • 71
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    ISBN: 9789533073408 , 9789535165248
    Language: English
    Pages: 1 Online-Ressource (362 p.)
    Keywords: Endocrinology
    Abstract: This book provides the most up-to-date information on the basic and clinical aspects of endocrinology. It offers both researchers and clinicians experts, gold-standard analysis of endocrine research and translation into the treatment of diseases such as insulinoma, endocrine disease in pregnancy and steroid induced osteoporosis. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. Presents a uniquely comprehensive look at all aspects of endocrine changes in pregnancy and cardiovascular effects of androgens
    Note: English
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  • 72
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    ISBN: 9789533077390 , 9789535165491
    Language: English
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Endocrinology
    Abstract: This book is intended to act as an up to date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular Ulcerative Colitis. All of the chapter authors are experts in their fields of publication and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine
    Note: English
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  • 73
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    ISBN: 9789533073675 , 9789535165712
    Language: English
    Pages: 1 Online-Ressource (150 p.)
    Keywords: Endocrinology
    Abstract: The first chapter of the book reports on the management of Langerhans cell histiocytosis (LCH)-induced central diabetes insipidus and its associated endocrinological/neurological sequelae in the national survey. The next chapter addresses DI and head injuries. Next, the management of neuroendocrine instability during maintenance of potential organ donors is described. Organ transplants have gradually increased worldwide. To have maintenance of appropriate potential organs, AVP is needed. Furthermore, nephrogenic DI-the potential therapeutic drugs and analysis of membrane protein stability is the topic of the next two chapters, followed by new insights into the diagnosis and management of pregnancy-related DI. The seventh chapter reports on the problems with differential diagnosis in a case of central DI in a female patient with bipolar disorder. The lithium treatment usually resulted in nephrogenic DI. Finally, over the last years, the development of MRI imaging on the pituitary gland with the stalk and hypothalamus has advanced. The final chapter interprets imaging techniques in DI in detail
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  • 74
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    ISBN: 9789533075983 , 9789535164951
    Language: English
    Pages: 1 Online-Ressource (384 p.)
    Keywords: Endocrinology
    Abstract: Adipocytes are important in the body for maintaining proper energy balance by storing excess energy as triglycerides. However, efforts of the last decade have identified several molecules that are secreted from adipocytes, such as leptin, which are involved in signaling between tissues and organs. These adipokines are important in overall regulation of energy metabolism and can regulate body composition as well as glucose homeostasis. Excess lipid storage in tissues other than adipose can result in development of diabetes and nonalcoholic fatty liver disease (NAFLD). In this book we review the role of adipocytes in development of insulin resistance, type 2 diabetes and NAFLD. Because type 2 diabetes has been suggested to be a disease of inflammation we included several chapters on the mechanism of inflammation modulating organ injury. Finally, we conclude with a review on exercise and nutrient regulation for the treatment of type 2 diabetes and its co-morbidities
    Note: English
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    ISBN: 9789533079769 , 9789535167761
    Language: English
    Pages: 1 Online-Ressource (502 p.)
    Keywords: Endocrinology
    Abstract: Peptic ulcer disease is one of the most common chronic infections in human population. Despite centuries of study, it still troubles a lot of people, especially in the third world countries, and it can lead to other more serious complications such as cancers or even to death sometimes. This book is a snapshot of the current view of peptic ulcer disease. It includes 5 sections and 25 chapters contributed by researchers from 15 countries spread out in Africa, Asia, Europe, North America and South America. It covers the causes of the disease, epidemiology, pathophysiology, molecular-cellular mechanisms, clinical care, and alternative medicine. Each chapter provides a unique view. The book is not only for professionals, but also suitable for regular readers at all levels
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    ISBN: 9789533075815 , 9789535165484
    Language: English
    Pages: 1 Online-Ressource (394 p.)
    Keywords: Endocrinology
    Abstract: Gestational diabetes mellitus is defined as hyperglycemia with onset or first recognition during pregnancy. The incidence of gestational diabetes is still increasing and this pathological condition has strong association with adverse pregnancy outcomes. Since gestational diabetes can have long-term pathological consequences for both mother and the child, it is important that it is promptly recognized and adequately managed. Treatment of gestational diabetes is aimed to maintain euglycemia and it should involve regular glucose monitoring, dietary modifications, life style changes, appropriate physical activity, and when necessary, pharmacotherapy. Adequate glycemic control throughout the pregnancy can notably reduce the occurrence of specific adverse perinatal and maternal outcomes. In a long-term prospect, in order to prevent development of diabetes later in life, as well to avoid associated complications, an adequate education on lifestyle modifications should start in pregnancy and continue postpartum
    Note: English
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    ISBN: 9789533076577 , 9789535165200
    Language: English
    Pages: 1 Online-Ressource (252 p.)
    Keywords: Endocrinology
    Abstract: Glucose is an essential metabolic substrate of all mammalian cells being the major carbohydrate presented to the cell for energy production and also many other anabolic requirements. Hypoglycemia is a disorder where the glucose serum concentration is usually low. The organism usually keeps the glucose serum concentration in a range of 70 to 110 mL/dL of blood. In hypoglycemia the glucose concentration normally remains lower than 50 mL/dL of blood. This book provides an abundance of information for all who need them in order to help many people worldwide
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    ISBN: 9789533078830 , 9789535167488
    Language: English
    Pages: 1 Online-Ressource (390 p.)
    Keywords: Endocrinology
    Abstract: Liver biopsy, first performed by Paul Ehrlich in 1883, remains an important diagnostic procedure for the management of hepatobiliary disorders and the candidate/donated organ for transplantation. The book "Liver biopsy in Modern Medicine" comprises 21 chapters covering the various aspects of the biopsy procedure in detail and provides an up-to-date insightful coverage to the recent advances in the management of the various disorders with liver biospy. This book will keep up with cutting edge understanding of liver biopsy to many clinicians, physicians, scientists, pharmaceutics, engineers and other experts in a wide variety of different disciplines
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    ISBN: 9789533076607 , 9789535165194
    Language: English
    Pages: 1 Online-Ressource (266 p.)
    Keywords: Endocrinology
    Abstract: Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future
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  • 80
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    ISBN: 9789533073651 , 9789535165958
    Language: English
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Endocrinology
    Abstract: The gastrostomy placement is a method of providing nutrition to the patients who are unable to eat. In this book you can find chapters focused on the use of gastrostomy in children, patients with neurological impairment and patients with head and neck tumours. Home enteral nutrition is suitable for all of these groups of patients and is far easier with gastrostomy. The new indications (especially in very young children) required new techniques such as: laparoscopic gastrostomy, laparoscopy assisted endoscopic gastrostomy with/without fundoplication, ultrasonography assisted gastronomy. All information about these techniques can be found in this book. This book does not serve as a basic textbook, but as an interesting reading material and as an aid for physicians who are already familiar with the indication for gastrostomy and want to know more
    Note: English
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    ISBN: 9789533076447 , 9789535164715
    Language: English
    Pages: 1 Online-Ressource (416 p.)
    Keywords: Endocrinology
    Abstract: Liver biopsy is recommended as the gold standard method to determine diagnosis, fibrosis staging, prognosis and therapeutic indications in patients with chronic liver disease. However, liver biopsy is an invasive procedure with a risk of complications which can be serious. This book provides the management of the complications in liver biopsy. Additionally, this book provides also the references for the new technology of liver biopsy including the non-invasive elastography, imaging methods and blood panels which could be the alternatives to liver biopsy. The non-invasive methods, especially the elastography, which is the new procedure in hot topics, which were frequently reported in these years. In this book, the professionals of elastography show the mechanism, availability and how to use this technology in a clinical field of elastography. The comprehension of elastography could be a great help for better dealing and for understanding of liver biopsy
    Note: English
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  • 82
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    ISBN: 9789533077888 , 9789535165842
    Language: English
    Pages: 1 Online-Ressource (494 p.)
    Keywords: Endocrinology
    Abstract: This book is a compilation of reviews about the complication of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. The complications associated with T1D cover a range of clinical obstacles. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes
    Note: English
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