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  • Undetermined  (10)
  • [Erscheinungsort nicht ermittelbar] : Springer Nature
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  • 1
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    Chapter Slow Violence and Slow Going : Encountering Beckett in the Time of Climate Catastrophe (2023)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
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    ISBN: 9783031083679 , 9783031083709
    Language: Undetermined
    Pages: 1 Online-Ressource (12 p.)
    Keywords: Climate change
    Abstract: This This chapter reads Beckett’s fascination with what Steven Connor has called ‘slow going’ alongside Rob Nixon’s description of the ‘slow violence’ of climate breakdown. Following Nixon’s suggestion that ‘slow violence’ does not register readily in narratives and temporalities of crisis, I examine Beckett’s attention to what remains in a paradoxically stuck and ongoing time. Suggesting that Beckett’s work sticks with and witnesses catastrophe rather than crisis, the chapter uses The Lost Ones to explore Beckett’s commitment to staying with a disaster that cannot be overcome, alongside the articulation of a giving up that is not a decision but part of a drive to go on. Using Beckett’s interest in Freud’s death drive, I suggest that Beckett’s later texts work through materialisations of attachment and dependence as a way of thinking with and living with, rather than denying or repressing, the reality of the ‘nothing to be done’
    Note: English
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  • 2
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    Samuel Beckett and Catastrophe (2023)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783031083686 , 9783031083679 , 9783031083709
    Language: Undetermined
    Pages: 1 Online-Ressource (221 p.)
    Keywords: Literary studies: from c 1900 - ; Beckett; Catastrophe; twentieth century literature; war; holocaust; nuclear disaster; ecological crisis; catastrophes in history; psychoanalysis; philosophy; fascism; worl war II; cold war; anthropocene; endgame
    Abstract: Samuel Beckett and Catastrophe is a groundbreaking collection of original essays that explore the relation between Samuel Beckett and catastrophe in terms of war, the Holocaust, nuclear disasters and ecological crisis. Responding to the post-catastrophic situations in the twentieth century, Beckett created characters who often seem to have been through an unknown catastrophe. Although the importance of catastrophe in Beckett has been noted sporadically, there has been no substantial attempt to discuss his aesthetics and work in relation to it. This collection will therefore serve as the first sustained study to explore the theme of catastrophe in Beckett and will be a highly significant contribution to Beckett studies. Chapter “Slow Violence and Slow Going: Encountering Beckett in the Time of Climate Catastrophe” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
    Note: English
    URL: teilw. kostenfrei
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  • 3
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    Chapter 4 Obesity Is a Disease (2022)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
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    ISBN: 9783030833992 , 9783030833985
    Language: Undetermined
    Pages: 1 Online-Ressource (6 p.)
    Keywords: Diseases & disorders
    Abstract: Obesity is a subcortical brain disease characterised by the pathognomonic symptoms of excessive hunger and/or reduced satiation after a meal. Distinct subtypes of obesity are recognised, although the rising incidence of polygenic obesity resulting from incompletely elucidated gene-environment interactions is of greatest public health concern. Obesity complications are well documented; their reversal with sustained intentional weight loss is a reason for optimism and motivation to seek treatments targeting pathophysiological mechanisms of obesity. Although lifestyle modification to achieve net energy deficit represents an important facet of obesity management, it is imperative to remember that hypothalamic dysfunction underpins this dysregulated state of energy metabolism and that solely appealing to patients’ cerebral cortices through motivational strategies will ultimately prove futile for many. Most patients will regain all the weight that they have lost if the treatment strategy does not make them less hungry and/or more satisfied with smaller meals (Dombrowski et al. 2014). Instead, we must expand our understanding of the pathophysiology of obesity and target our treatments to correct the subcortical brain disturbances which perpetuate aberrant feeding behaviours. Until our clinical tools improve, we can serve our patients better by recognising obesity as a disease and treating it with the same strategies and compassion we apply to all other chronic and disabling diseases
    Note: English
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  • 4
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    Bariatric Surgery in Clinical Practice (2022)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030833992 , 9783030833985
    Language: Undetermined
    Pages: 1 Online-Ressource
    Series Statement: In Clinical Practice (ICP)
    Keywords: Diseases & disorders ; Diseases and disorders ; obesity; disease; bariatric surgery; clinical practice
    Abstract: obesity; disease; bariatric surgery; clinical practice
    Note: English
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  • 5
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    Chapter 8 Painful Experience and Constitution of the Intersubjective Self : A Critical-Phenomenological Analysis (2021)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030656133 , 9783030656126 , 9783030656157
    Language: Undetermined
    Pages: 1 Online-Ressource (14 p.)
    Keywords: Phenomenology & Existentialism
    Abstract: In this paper, we discuss how phenomenology might cogently express the way painful experiences are layered with complex intersubjective meaning. In particular, we propose a critical conception of pain as an intricate multi-levelled phenomenon, deeply ingrained in the constitution of one's sense of bodily self and emerging from a web of intercorporeal, social, cultural, and political relations. In the first section, we review and critique some conceptual accounts of pain. Then, we explore how pain is involved in complex ways with modalities of pleasure and displeasure, enacted personal meaning, and contexts of empathy or shame. We aim to show why a phenomenology of pain must acknowledge the richness and diversity of peculiar painful experiences. The second section then weaves these critical insights into Husserlian phenomenology of embodiment, sensation, and localisation. We introduce the distinction between Body-Object and Lived-Body to show how pain presents intersubjectively (e.g. from a patient to a clinician). Furthermore, we stress that,while pain seems to take amarginal position inHusserl's whole corpus, its role is central in the transcendental constitution of the Lived-Body, interacting with the personal, interpersonal, and intersubjective levels of experiential constitution. Taking a critical-phenomenological perspective,wethen concretely explore how some peoplemay experience structural conditions whichmay make their experiences more or less painful
    Note: English
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  • 6
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    Phenomenology of Bioethics : Technoethics and Lived-Experience (2021)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
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    ISBN: 9783030656133 , 9783030656126 , 9783030656157
    Language: Undetermined
    Pages: 1 Online-Ressource (147 p.)
    Series Statement: The International Library of Bioethics
    Keywords: Bio-ethics ; Phenomenology & Existentialism ; Bioethics ; Phenomenology and Existentialism ; bioethics; phenomenology
    Abstract: This book offers a unique description of how phenomenology can help professionals from medical, environmental and social fields to explore notions such as interaffectivity, empathy, epoche, reduction, and intersubjective encounter. Written by a group of top scholars, it uniquely covers the relationship between phenomenology and bioethics, and focuses not only on medical cases, but also on the environment and emerging technologies. This variety of themes, whilst including techno-ethics, environmental ethics, animal ethics, and medical ethics, is conducive to appreciating broadly how phenomenology can improve our quality of our life. Despite its difficult themes, the book appeals to an audience of both academics and professionals who are willing to understand how to increase the quality of care in their professional field. Chapter 8 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
    Note: English
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  • 7
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    Chapter Broadband NIRS Cerebral Evaluation of the Hemodynamic and Oxidative State of Cytochrome-c-Oxidase Responses to +Gz Acceleration in Healthy Volunteers (2020)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030344610 , 9783030344597
    Language: Undetermined
    Pages: 1 Online-Ressource (7 p.)
    Keywords: Medical equipment & techniques
    Abstract: We used a miniature broadband NIRS system to monitor concentration changes in brain oxygenation (oxy- and deoxy- haemoglobin [HbO2], [HHb]) and oxidised cytochrome-c-oxidase ([oxCCO]) during a high +Gz acceleration, induced by a human centrifuge, on two healthy experienced volunteers (2 male, 34 and 37 years). We performed a sequence of several +Gz exposures that were terminated at the onset of visual symptoms (loss of peripheral vision). Systemic parameters were recorded (i.e. heart rate, blood pressure and arterial saturation), and brain tissue blood volume changes ([HbT] = [HbO2] + [HHb]) and oxygen delivery ([HbDiff] = [HbO2] - [HHb]) were calculated. Volunteer 1 demonstrated a decrease in [HbT] of −3.49 ± 0.02 μMol and [HbDiff] of −3.23 ± 0.44 μMol, and an increase of [oxCCO] of 0.42 ± 0.01μMol. Volunteer 2 demonstrated a decrease in [HbDiff] of −4.37 ± 0.23 μMol, and no significant change in [HbT] (0.53 ± 0.06 μMol) and [oxCCO] (0.09 ± 0.06 μMol). The variability of the brain metabolic response was related to the level of ischaemia, suggesting that suppression of metabolism was due to lack of glucose substrate delivery rather than oxygen availability
    Note: English
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  • 8
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    Chapter Developing a Model to Simulate the Effect of Hypothermia on Cerebral Blood Flow and Metabolism (2020)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030344610 , 9783030344597
    Language: Undetermined
    Pages: 1 Online-Ressource (8 p.)
    Keywords: Biology, life sciences
    Abstract: Hypoxic ischemic encephalopathy (HIE) is a significant cause of death and neurological disability in newborns. Therapeutic hypothermia at 33.5 °C is one of the most common treatments in HIE and generally improves outcome; however 45-55% of injuries still result in death or severe neurodevelopmental disability. We have developed a systems biology model of cerebral oxygen transport and metabolism to model the impact of hypothermia on the piglet brain (the neonatal preclinical animal model) tissue physiology. This computational model is an extension of the BrainSignals model of the adult brain. The model predicts that during hypothermia there is a 5.1% decrease in cerebral metabolism, 1.1% decrease in blood flow and 2.3% increase in cerebral tissue oxygenation saturation. The model can be used to simulate effects of hypothermia on the brain and to help interpret bedside recordings
    Note: English
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  • 9
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    Chapter Near-Infrared Spectroscopy Measured Cerebral Blood Flow from Spontaneous Oxygenation Changes in Neonatal Brain Injury (2020)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030344610 , 9783030344597
    Language: Undetermined
    Pages: 1 Online-Ressource (7 p.)
    Keywords: Neonatal medicine
    Abstract: Neonates with hypoxic-ischaemic (HI) brain injury were monitored using a broadband near-infrared spectroscopy (NIRS) system in the neonatal intensive care unit. The aim of this work is to use the NIRS cerebral oxygenation data (HbD = oxygenated-haemoglobin - deoxygenated-haemoglobin) combined with arterial saturation (SaO2) from pulse oximetry to calculate cerebral blood flow (CBF) based on the oxygen swing method, during spontaneous desaturation episodes. The method is based on Fick's principle and uses HbD as a tracer; when a sudden change in SaO2 occurs, the change in HbD represents a change in tracer concentration, and thus it is possible to estimate CBF. CBF was successfully calculated with broadband NIRS in 11 HIE infants (3 with severe injury) for 70 oxygenation events on the day of birth. The average CBF was 18.0 ± 12.7 ml 100 g−1 min−1 with a range of 4 ml 100 g−1 min−1 to 60 ml 100 g−1 min−1. For infants with severe HIE (as determined by magnetic resonance spectroscopy) CBF was significantly lower (p = 0.038, d = 1.35) than those with moderate HIE on the day of birth
    Note: English
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  • 10
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    Oxygen Transport to Tissue XLI (2020)
    [Erscheinungsort nicht ermittelbar] : Springer Nature
    Details
    ISBN: 9783030344597 , 9783030344610
    Language: Undetermined
    Pages: 1 Online-Ressource (431 p.)
    Series Statement: Advances in Experimental Medicine and Biology
    Keywords: Biomedical engineering ; oxygenation; hypoxia; cerebral blood flow; oxygen supply; tissue oximeter
    Abstract: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 46th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2018) held in Seoul, Republic of Korea, from July 1 to July 5, 2018. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource. The chapters "Near-Infrared Spectroscopy Measured Cerebral Blood Flow from Spontaneous Oxygenation Changes in Neonatal Brain Injury", "Developing a Model to Simulate the Effect of Hypothermia on Cerebral Blood Flow and Metabolism" and "Broadband NIRS Cerebral Evaluation of the Hemodynamic and Oxidative State of Cytochrome-c-Oxidase Responses to +Gz Acceleration in Healthy Volunteers" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
    Note: English
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