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  • 2010-2014  (57)
  • 2005-2009
  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (57)
  • Cambridge : Cambridge University Press
  • Cardiovascular medicine  (57)
Datasource
Material
Language
Years
Year
Author, Corporation
Publisher
Keywords
  • 1
    Online Resource
    Online Resource
    Carotid Artery Disease : From Bench to Bedside and Beyond (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112143 , 9789535171898
    Language: English
    Pages: 1 Online-Ressource (232 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book will bring out the state of art of carotid stenosis in the basic and clinical approaches for better understanding of the mechanisms and useful therapies for these disease. We hope that would be a new current trend understanding new aspects regarding this scientific problematic involving not only anatomical, functional but also clinical questions
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 2
    Online Resource
    Online Resource
    Calcific Aortic Valve Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111504 , 9789535171638
    Language: English
    Pages: 1 Online-Ressource (542 p.)
    Keywords: Cardiovascular medicine
    Abstract: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future
    Note: English
    URL: kostenfrei
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  • 3
    Online Resource
    Online Resource
    Recent Advances in Infective Endocarditis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111696 , 9789535171690
    Language: English
    Pages: 1 Online-Ressource (134 p.)
    Keywords: Cardiovascular medicine
    Abstract: Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery
    Note: English
    URL: kostenfrei
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  • 4
    Online Resource
    Online Resource
    Research Directions in Tumor Angiogenesis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109631 , 9789535170792
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Cardiovascular medicine
    Abstract: Angiogenesis is an extension process of the cardiovascular network within human body. It is usually triggered by the demand of oxygen and nutrients from the fast growing tissue and uncontrollably dividing cells, as seen during wound healing and tumor progression. This book focuses on tumor angiogenesis and includes 8 chapters written by highly experienced scholars from five different countries. It is the goal of this book to provide readers with an update on the molecular and cellular mechanisms of this biological process and hopefully to point out some new research directions for future therapeutic adventure
    Note: English
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  • 5
    Online Resource
    Online Resource
    Atrial Fibrillation : Mechanisms and Treatment (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110231 , 9789535171041
    Language: English
    Pages: 1 Online-Ressource (248 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atrial fibrillation is a rapidly evolving epidemic associated with increased cardiovascular morbidity and mortality, and its prevalence has increased over the past few decades. In the past few years, the recent understanding of the diverse mechanisms of this arrhythmia has lead to the improvement of our therapeutic strategies. However, many clinicians have still felt the frustration in management of this commonly encountered arrhythmia. This book contains a spectrum of different topics from bench to bedside in atrial fibrillation. We strongly believe that scientists, cardiologists and electrophysiologists will find this book very informative and useful and the references cited in each chapter will definitely act as an additional source of information for readers
    Note: English
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  • 6
    Online Resource
    Online Resource
    Hot Topics in Echocardiography (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112044 , 9789535171850
    Language: English
    Pages: 1 Online-Ressource (148 p.)
    Keywords: Cardiovascular medicine
    Abstract: Echocardiography is still the most used imaging technique for the evaluation of cardiac anatomy and function and today it plays an essential role in daily decision making. The echocardiographic technology and its applications have widely developed in the last years leading to a better diagnostic accuracy. On the other hand echocardiography specialists have new clinical questions to answer. Echocardiography meets the growing need for non-invasive imaging in the expanding heart failure population and during structural heart interventions. The new percutaneous therapies need, a precise evaluation of cardiac dimensions and a complete understanding of the spatial relationships between cardiac structures. Echocardiography is of paramount importance both during the patient evaluation and guiding the procedure. This book tries to give an in depth evaluation about the specific issues that a modern cardiovascular imaging specialist is asked to answer nowadays
    Note: English
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  • 7
    Online Resource
    Online Resource
    Artery Bypass (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110255 , 9789535171126
    Language: English
    Pages: 1 Online-Ressource (548 p.)
    Keywords: Cardiovascular medicine
    Abstract: The latest diagnostic and therapeutic modalities in the management of coronary artery disease by coronary artery bypass graft surgery and by percutaneous coronary intervention with stenting and in the interventional management of other atherosclerotic vascular disease have led to a reduction in cardiovascular mortality and morbidity. This book entitled Artery Bypass provides an excellent update on these advances which every physician seeing patients with atherosclerotic vascular disease should be familiar with. This book includes 27 chapters written by experts in their topics
    Note: English
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  • 8
    Online Resource
    Online Resource
    What Should We Know About Prevented, Diagnostic, and Interventional Therapy in Coronary Artery Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110439 , 9789535171164
    Language: English
    Pages: 1 Online-Ressource (484 p.)
    Keywords: Cardiovascular medicine
    Abstract: The mortality from ischemic heart disease has decreased in recent years. The better understanding of risk factors associated with development of coronary artery disease has significantly contributed to this decline. Improvements in medical and interventional therapy have reduced the complications associated with acute myocardial infarction as well as revascularization. After the introduction of imaging modalities, the noninvasive characterization of regional function, perfusion and metabolism allowed for more sophisticated tissue characterization to identify reversible dysfunction with high diagnostic and prognostic accuracy. We now can legitimately claim that computed tomography angiography (CTA) of the coronary arteries is available. In the evaluation of patients with suspected coronary artery disease, many guidelines today consider CTA an alternative to stress testing. However the nuclear technique most frequently used by cardiologists is myocardial perfusion imaging (MPI). The combination of a nuclear camera with CTA allows for the attainment of coronary anatomic, cardiac function and MPI from one piece of equipment. Assessing cardiac viability is now fairly routine with these enhancements to cardiac imaging. Traditional coronary angiography presents a variety of limitations related to image acquisition, content, interpretation, and patient safety. Barriers to such improvements include the paucity of clinical outcomes studies related to new imaging technology, the need for physician and staff member training, and the costs associated with acquiring and effectively using these advances in coronary angiography. This issue is full of important information that every cardiologist needs to now
    Note: English
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  • 9
    Online Resource
    Online Resource
    Arteriovenous Fistulas : Diagnosis and Management (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111788 , 9789535171720
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Cardiovascular medicine
    Abstract: Arteriovenous fistulas are shunts between arteries and veins that can be found in many organs of the human body such as the brain, skin, eye and lung. These lesions can be symptomatic by causing ischemia, through the process of the steal phenomenon, or vascular congestion and subsequent hemorrhage, eg. intracerebral hemorrhage of a ruptured dural arteriovenous fistula. The etiology of these lesions is not fully understood, some are congenital and others are acquired. On the other hand, iatrogenic arteriovenous fistulas, such as in hemodialysis patients, can be a life-saving procedure. This book provides a clear and concise review of the diagnosis and management of arteriovenous fistulas throughout the human body. It could be a great resource to medical students, residents, fellows, professors and researchers in the field
    Note: English
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  • 10
    Online Resource
    Online Resource
    Diagnosis and Treatment of Myocarditis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110828 , 9789535171393
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Cardiovascular medicine
    Abstract: Myocarditis is a clinical syndrome, most frequently of infectious etiology, that occurs with a broad range of relatively non-specific symptoms, and consists of an inflammatory process of the heart with necrosis and degeneration of the myocardium by inflammatory infiltration of immune cells. The infection can cause direct injury of cardiomyocytes as well as immune-mediated destruction of the myocardium, leading to cardiac dysfunction. In this book, the broad aspects of myocarditis are fully presented by leading international experts. The texts are devoted to both clinical aspects and pathophysiology, and they present comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment, as well as myocarditis in special populations such as pediatric, peripartum and chronic chagasic myocarditis
    Note: English
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  • 11
    Online Resource
    Online Resource
    Ischemic Heart Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109938 , 9789535170921
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular disease (CVD) is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. A coronary even occurs every 25 seconds and CVD kills one person every 34 seconds. 35 people under 65 years of age die prematurely every day due to CVD. The incidence of CVD has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy, new drug regimens and advances in acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text reviews the epidemiology, development, risk factors, diagnosis and treatment of ischemic heart disease
    Note: English
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  • 12
    Online Resource
    Online Resource
    Cardiomyopathies (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111030 , 9789535171614
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Cardiovascular medicine
    Abstract: The disease of the heart muscle may occur secondarily to common diseases, such as ischemic, hypertensive and valvular, among others. However, there is a group of conditions with intrinsic myocardial involvement from gene or multifactorial etiology, and high morbidity and mortality that represent a diagnostic and therapeutic challenge for the physician. The book is focused on these cardiomyopathies, its features, its pathophysiology and its relation to sudden death. Mention is made also on general aspects, like ecocardiographic findings and myocardial contractile reserve, specific as pathophysiology and molecular mechanisms and cardiomyopathies in special populations. Special attention was deserved to cardiomyopathies in pediatrics, diabetic patients and women, as well as to the cases of chronic heart failure and dilated cardiomyopathy
    Note: English
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  • 13
    Online Resource
    Online Resource
    Basic Cardiopulmonary Resuscitation Manual (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112013 , 9789535171867
    Language: Undetermined
    Pages: 1 Online-Ressource (82 p.)
    Keywords: Cardiovascular medicine
    Abstract: The purpose of this publication is to systematize the knowledge necessary to make Cardiopulmonary Resuscitation (CPR) or Cardiorespiratory Resuscitation (CRR) known to nursing health specialists, which translates as a set of temporary and internationally standardized maneuvers assigned to ensure the oxygenation of the vital organs when the blood circulation of an individual stops suddenly, independently of the cause of the Cardiorespiratory arrest (CRA). This knowledge is found correctly delimited in The Basic Cardiopulmonary Resuscitation Manual, which especially emphasizes the step-by-step methodology and techniques to follow for Cardiopulmonary Resuscitation (CPR). This is a basic work that cannot be overlooked by health care specialists, the society, and the public in general, because of the high probability that this situation will present at some moment in life. Thus, it is recommended to be prepared to help some person in an emergency situation. The manual is an excellent consultation work for health professionals. Given that what is expressed in this work is fundamental for life, and its objective is to make known the relevant information concerning the knowledge of CPR
    Note: English
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  • 14
    Online Resource
    Online Resource
    Coronary Artery Disease : Current Concepts in Epidemiology, Pathophysiology, Diagnostics and Treatment (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102625 , 9789535168904
    Language: English
    Pages: 1 Online-Ressource (288 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular disease is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. Heart disease kills one person every 34 seconds in the USA alone. Although the leading killer, the incidence of cardiovascular disease has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy new drug regimens including low molecular weight heparin and antiplatelet drugs such as glycoprotein IIb/IIIa receptor inhibitors and acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text aims to deliver the current understanding of coronary artery disease and is split into three main sections: 1. Epidemiology and pathophysiology of coronary artery disease 2. Coronary artery disease diagnostics and 3. Treatment regimens for coronary artery disease
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  • 15
    Online Resource
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    Cardiac Arrhythmias : New Considerations (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535101260 , 9789535168379
    Language: English
    Pages: 1 Online-Ressource (546 p.)
    Keywords: Cardiovascular medicine
    Abstract: The most intimate mechanisms of cardiac arrhythmias are still quite unknown to scientists. Genetic studies on ionic alterations, the electrocardiographic features of cardiac rhythm and an arsenal of diagnostic tests have done more in the last five years than in all the history of cardiology. Similarly, therapy to prevent or cure such diseases is growing rapidly day by day. In this book the reader will be able to see with brighter light some of these intimate mechanisms of production, as well as cutting-edge therapies to date. Genetic studies, electrophysiological and electrocardiographyc features, ion channel alterations, heart diseases still unknown , and even the relationship between the psychic sphere and the heart have been exposed in this book. It deserves to be read!
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  • 16
    Online Resource
    Online Resource
    Aneurysm (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535107309 , 9789535170259
    Language: English
    Pages: 1 Online-Ressource (488 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book's focus is on diagnosis and treatment of intracranial aneurysm, abdominal and thoracic aortic aneurysms. It addresses neurosurgical, vascular and cardiothoracic surgeons and interventional radiologists, but also anyone engaged in vascular medicine. It presents is an effort to collect an up-to-date account of existing knowledge, involving recent developments in this field. Various experts described details of established knowledge or newly recognized advances associated with diagnosis, treatment, perioperative management and mechanism. This is the first book that deals with the whole body aneurysm, such as cerebral aneurysm, abdominal aneurysm, and splenial aneurysm and to learn the latest developments in other fields is always useful. I hope this book will be used worldwide by vascular surgeons and interventionalists enhancing their knowledge and stimulating the advancement of this field
    Note: English
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  • 17
    Online Resource
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    Novel Strategies in Ischemic Heart Disease (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535101840 , 9789535168621
    Language: English
    Pages: 1 Online-Ressource (464 p.)
    Keywords: Cardiovascular medicine
    Abstract: The first edition of this book will provide a comprehensive overview of ischemic heart disease, including epidemiology, risk factors, pathogenesis, clinical presentation, diagnostic tests, differential diagnosis, treatment, complications and prognosis. Also discussed are current treatment options, protocols and diagnostic procedures, as well as the latest advances in the field. The book will serve as a cutting-edge point of reference for the basic or clinical researcher, and any clinician involved in the diagnosis and management of ischemic heart disease. This book is essentially designed to fill the vital gap existing between these practices, to provide a textbook that is substantial and readable, compact and reasonably comprehensive, and to provide an excellent blend of "basics to bedside and beyond" in the field of ischemic heart disease. The book also covers the future novel treatment strategies, focusing on the basic scientific and clinical aspects of the diagnosis and management of ischemic heart disease
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  • 18
    Online Resource
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    Recent Advances in Cardiovascular Risk Factors (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535103219 , 9789535169109
    Language: English
    Pages: 1 Online-Ressource (526 p.)
    Keywords: Cardiovascular medicine
    Abstract: Among the non-communicable diseases, cardiovascular disorders are the leading cause of morbidity and mortality in both the developed and the developing countries. The spectrum of risk factors is wide and their understanding is imperative to prevent the first and recurrent episodes of myocardial infarction, stroke or peripheral vascular disease which may prove fatal or disabling. This book has tried to present an update on risk factors incorporating new research which has thrown more light on the existing knowledge. It has also tried to highlight regional diversity addressing such issues. It will hopefully be resourceful to the cardiologists, general practitioners, family physicians, researchers, graduate students committed to cardiovascular risk prevention
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  • 19
    Online Resource
    Online Resource
    Chronic Lymphocytic Leukemia (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078816 , 9789535167464
    Language: English
    Pages: 1 Online-Ressource (464 p.)
    Keywords: Cardiovascular medicine
    Abstract: B-cell chronic lymphocytic leukemia (CLL) is considered a single disease with extremely variable course, and survival rates ranging from months to decades. It is clear that clinical heterogeneity reflects biologic diversity with at least two major subtypes in terms of cellular proliferation, clinical aggressiveness and prognosis. As CLL progresses, abnormal hematopoiesis results in pancitopenia and decreased immunoglobulin production, followed by nonspecific symptoms such as fatigue or malaise. A cure is usually not possible, and delayed treatment (until symptoms develop) is aimed at lengthening life and decreasing symptoms. Researchers are playing a lead role in investigating CLL's cause and the role of genetics in the pathogenesis of this disorder. Research programs are dedicated towards understanding the basic mechanisms underlying CLL with the hope of improving treatment options
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  • 20
    Online Resource
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    Current Issues and Recent Advances in Pacemaker Therapy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107033 , 9789535170235
    Language: English
    Pages: 1 Online-Ressource (300 p.)
    Keywords: Cardiovascular medicine
    Abstract: Patients with implanted pacemakers or defibrillators are frequently encountered in various healthcare settings. As these devices may be responsible for, or contribute to a variety of clinically significant issues, familiarity with their function and potential complications facilitates patient management. This book reviews several clinically relevant issues and recent advances of pacemaker therapy: implantation, device follow-up and management of complications. Innovations and research on the frontiers of this technology are also discussed as they may have wider utilization in the future. The book should provide useful information for clinicians involved in the management of patients with implanted antiarrhythmia devices and researchers working in the field of cardiac implants
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  • 21
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    Coronary Interventions (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104988 , 9789535169604
    Language: English
    Pages: 1 Online-Ressource (254 p.)
    Keywords: Cardiovascular medicine
    Abstract: Given the prevalence of heart conditions in modern populations, new techniques for treating patients are highly warranted. This book will be required reading for researchers and healthcare practitioners, as it offers assessments of complications, the new transradial approach and an overview of drug-eluting stents. A special focus on percutaneous coronary interventions is evident, from chapters on pharmacotherapy, its relevance to 30-day mortality and the CANADA score, besides the treatment of patients with saphenous vein graft disease. Other treatment protocols addressed include therapeutic hypothermia and the drug-eluting balloon, cardiac postconditioning to limit cell death following myocardial infarction and rotablation in the drug-eluting Syent era. There is also a chapter on using contrast medium-induced nephropathy gram-iodine/GFR ratio to predict CIN
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  • 22
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    Acute Coronary Syndromes (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078274 , 9789535167075
    Language: English
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book has been written with the intention of providing an up-to-the minute review of acute coronary syndromes. Atherosclerotic coronary disease is still a leading cause of death within developed countries and not surprisingly, is significantly rising in others. Over the past decade the treatment of these syndromes has changed dramatically. The introduction of novel therapies has impacted the outcomes and surviving rates in such a way that the medical community need to be up to date almost on a "daily bases". It is hoped that this book will provide a timely update on acute coronary syndromes and prove to be an invaluable resource for practitioners seeking new and innovative ways to deliver the best possible care to their patients
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  • 23
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    Advances in Electrocardiograms : Clinical Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079028 , 9789535167570
    Language: English
    Pages: 1 Online-Ressource (342 p.)
    Keywords: Cardiovascular medicine
    Abstract: Electrocardiograms have become one of the most important, and widely used medical tools for diagnosing diseases such as cardiac arrhythmias, conduction disorders, electrolyte imbalances, hypertension, coronary artery disease and myocardial infarction. This book reviews recent advancements in electrocardiography. The four sections of this volume, Cardiac Arrhythmias, Myocardial Infarction, Autonomic Dysregulation and Cardiotoxicology, provide comprehensive reviews of advancements in the clinical applications of electrocardiograms. This book is replete with diagrams, recordings, flow diagrams and algorithms which demonstrate the possible future direction for applying electrocardiography to evaluating the development and progression of cardiac diseases. The chapters in this book describe a number of unique features of electrocardiograms in adult and pediatric patient populations with predilections for cardiac arrhythmias and other electrical abnormalities associated with hypertension, coronary artery disease, myocardial infarction, sleep apnea syndromes, pericarditides, cardiomyopathies and cardiotoxicities, as well as innovative interpretations of electrocardiograms during exercise testing and electrical pacing
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  • 24
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    Advances in Electrocardiograms : Methods and Analysis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079233 , 9789535167624
    Language: English
    Pages: 1 Online-Ressource (404 p.)
    Keywords: Cardiovascular medicine
    Abstract: Electrocardiograms are one of the most widely used methods for evaluating the structure-function relationships of the heart in health and disease. This book is the first of two volumes which reviews recent advancements in electrocardiography. This volume lays the groundwork for understanding the technical aspects of these advancements. The five sections of this volume, Cardiac Anatomy, ECG Technique, ECG Features, Heart Rate Variability and ECG Data Management, provide comprehensive reviews of advancements in the technical and analytical methods for interpreting and evaluating electrocardiograms. This volume is complemented with anatomical diagrams, electrocardiogram recordings, flow diagrams and algorithms which demonstrate the most modern principles of electrocardiography. The chapters which form this volume describe how the technical impediments inherent to instrument-patient interfacing, recording and interpreting variations in electrocardiogram time intervals and morphologies, as well as electrocardiogram data sharing have been effectively overcome. The advent of novel detection, filtering and testing devices are described. Foremost, among these devices are innovative algorithms for automating the evaluation of electrocardiograms
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  • 25
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    Atrial Fibrillation : Basic Research and Clinical Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533073996 , 9789535166252
    Language: English
    Pages: 1 Online-Ressource (416 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atrial Fibrillation-Basic Research and Clinical Applications is designed to provide a comprehensive review and to introduce outstanding and novel researches. This book contains 22 polished chapters and consists of five sections: 1. Basic mechanisms of initiation and maintenance of atrial fibrillation and its pathophysiology, 2. Mapping of atrial fibrillation and novel methods of signal detection. 3. Clinical prognostic predictors of atrial fibrillation and remodeling, 4. Systemic reviews of catheter-based/surgical treatment and novel targets for treatment of atrial fibrillation and 5. Atrial fibrillation in specific conditions and its complications. Each chapter updates the knowledge of atrial fibrillation, providing state-of-the art for not only scientists and clinicians who are interested in electrophysiology, but also general cardiologists
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  • 26
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    Cardiotoxicity of Oncologic Treatments (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102731 , 9789535168935
    Language: English
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Cardiovascular medicine
    Abstract: The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer
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  • 27
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    The Cardiovascular System : Physiology, Diagnostics and Clinical Implications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105343 , 9789535169741
    Language: English
    Pages: 1 Online-Ressource (494 p.)
    Keywords: Cardiovascular medicine
    Abstract: The cardiovascular system includes the heart located centrally in the thorax and the vessels of the body which carry blood. The cardiovascular (or circulatory) system supplies oxygen from inspired air, via the lungs to the tissues around the body. It is also responsible for the removal of the waste product, carbon dioxide via air expired from the lungs. The cardiovascular system also transports nutrients such as electrolytes, amino acids, enzymes, hormones which are integral to cellular respiration, metabolism and immunity. This book is not meant to be an all encompassing text on cardiovascular physiology and pathology rather a selection of chapters from experts in the field who describe recent advances in basic and clinical sciences. As such, the text is divided into three main sections: Cardiovascular Physiology, Cardiovascular Diagnostics and lastly, Clinical Impact of Cardiovascular Physiology and Pathophysiology
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  • 28
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    Oxidative Stress and Diseases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105527 , 9789535152828
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Cardiovascular medicine
    Abstract: The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pathologies in humans and animals. The chapters are organized into sections based on specific groups of pathologies such as cardiovascular diseases, diabetes, cancer, neuronal, hormonal, and systemic ones. A special section highlights potential of antioxidants to protect organisms against deleterious effects of reactive species. This book should appeal to many researchers, who should find its information useful for advancing their fields
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  • 29
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    Cardiovascular Risk Factors (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102403 , 9789535168812
    Language: English
    Pages: 1 Online-Ressource (506 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular risk factors contribute to the development of cardiovascular disease from early life. It is thus crucial to implement preventive strategies addressing the burden of cardiovascular disease as early as possible. A multidisciplinary approach to the risk estimation and prevention of vascular events should be adopted at each level of health care, starting from the setting of perinatology. Recent decades have been marked with major advances in this field, with the emergence of a variety of new inflammatory and immune-mediated markers of heightened cardiovascular risk in particular. The current book reflects some of the emerging concepts in cardiovascular pathophysiology and the shifting paradigm of cardiovascular risk estimation. It comprehensively covers primary and secondary preventive measures targeted at different age and gender groups. Attention is paid to inflammatory and metabolic markers of vascular damage and to the assessment of vascular function by noninvasive standardized ultrasound techniques. This is a must-read book for all health professionals and researchers tackling the issue of cardiovascular burden at individual and community level. It can also serve as a didactic source for postgraduate medical students
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  • 30
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    Congenital Heart Disease : Selected Aspects (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533074726 , 9789535166313
    Language: English
    Pages: 1 Online-Ressource (366 p.)
    Keywords: Cardiovascular medicine
    Abstract: There are significant advances in the understanding of the molecular mechanisms of cardiac development and the etiology of congenital heart disease (CHD). However, these have not yet evolved to such a degree so as to be useful in preventing CHD at this time. Developments such as early detection of the neonates with serious heart disease and their rapid transport to tertiary care centers, availability of highly sensitive noninvasive diagnostic tools, advances in neonatal care and anesthesia, progress in transcatheter interventional procedures and extension of complicated surgical procedures to the neonate and infant have advanced to such a degree that almost all congenital cardiac defects can be diagnosed and "corrected". Treatment of the majority of acyanotic and simpler cyanotic heart defects with currently available transcatheter and surgical techniques is feasible, effective and safe. The application of staged total cavo-pulmonary connection (Fontan) has markedly improved the long-term outlook of children who have one functioning ventricle. This book, I hope, will serve as a rich source of information to the physician caring for infants, children and adults with CHD which may help them provide optimal care for their patients
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  • 31
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    Traditional and Novel Risk Factors in Atherothrombosis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105619 , 9789535169826
    Language: English
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atherothrombosis has reached pandemic proportions worldwide. It is the underlying condition that results in events leading to myocardial infarction, ischemic stroke and vascular death. As such, it is the leading cause of death worldwide manifested mainly as cardiovascular/cerebrovascular death. The complex and intimate relationship between atherothrombosis and traditional and novel risk factors is discussed in the following chapters of Traditional and Novel Risk Factors in Atherothrombosis - from basic science to clinical and therapeutic concerns. Beginning with pathology and pathophysiology of atherothrombosis, plaque rupture/disruption, this book continues with molecular, biochemical, inflammatory, cellular aspects and finally analyzes several aspects of clinical pharmacology
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  • 32
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    Coronary Artery Diseases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102380 , 9789535168805
    Language: English
    Pages: 1 Online-Ressource (346 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book has "wide geography" both literally and figuratively. First of all, this book brings together contributions from around the world, both from post-industrial countries and developing world. This is natural, because coronary artery disease is becoming pandemic worldwide. CAD is the single most frequent cause of death in developed countries, causes about 1 in every 5 deaths. Mortality from cardiovascular disease is predicted to reach 23.4 million in 2030. Moreover, in the developing world, cardiovascular disease tends to affect people at a younger age and thus could negatively affect the workforce and economic productivity. The morbidity, mortality, and socioeconomic importance of CAD make its diagnosis and management fundamental for all practicing physicians. On another hand, the book widely represents "geography" of CAD itself, i.e. many various aspects of its pathophysiology, epidemiology, diagnosis, treatment are touched in this book. This book does not pretend on complete and integral description of the Coronary artery disease. Rather, it contains selected issues on this complex multifactorial disease. Nevertheless, we hope that readers will find Coronary Artery Disease useful for clinical practice and further research
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  • 33
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    Coronary Artery Disease : New Insights and Novel Approaches (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103448 , 9789535169192
    Language: English
    Pages: 1 Online-Ressource (272 p.)
    Keywords: Cardiovascular medicine
    Abstract: Coronary Artery disease is one of the leading causes of death in industrialized countries and is responsible for one out of every six deaths in the United States. Remarkably, coronary artery disease is also largely preventable. The biggest challenge in the next years is to reduce the incidence of coronary artery disease worldwide. A complete knowledge of the mechanisms responsible for the development of ischaemic heart disease is an essential prerequisite to a better management of this pathology improving prevention and therapy. This book has been written with the intention of providing new concepts about coronary artery disease pathogenesis that may link various aspects of the disease, going beyond the traditional risk factors
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  • 34
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    Venous Thrombosis : Principles and Practice (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078854 , 9789535167495
    Language: English
    Pages: 1 Online-Ressource (244 p.)
    Keywords: Cardiovascular medicine
    Abstract: According to Virchow's triad, venous thrombosis can occur as a result of one or more of three factors: changes in the dynamics of the blood flow, endothelial injury/dysfunction of the blood vessel and hypercoagulability. The blood in the veins is constantly forming microscopic thrombi that are routinely broken down by the body, and significant clotting can occur only when the balance of thrombus formation and resolution is altered. This book is a fresh synthesis of venous thromboembolism care and considers the opinions and studies from different fields of medicine. As venous thrombosis spectrum is wide and can affect many organ systems, from deep veins of the leg to the cerebral venous system, our intent is for this to be a comprehensive, up-to-date and readable book. We tried to present a synthesis of existing material infused with new ideas and perspectives and authors own clinical studies and even case-reports
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  • 35
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    Deep Vein Thrombosis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102250 , 9789535168713
    Language: English
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book provides a comprehensive review of deep vein thrombosis. There are chapters on risk factors for DVT, post thrombotic syndrome and its management, vena cava malformation as a new etiological factor and thrombosis in the upper limbs. DVT is usually seen in patients undergoing major surgeries. The guidelines for thrombo-prophylaxis in orthopaedic patients, radical pelvic surgeries, laparoscopic operations and risks versus benefits in regions with a low prevalence of DVT are thoroughly addressed. Cancer and its treatment are recognized risk factors for VTE and extended prophylaxis in ambulatory cancer patients is reviewed. The role of imaging and endovascular therapies in acute DVT, hypercoagulabilty in liver diseases and the challenges in developing countries are discussed
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  • 36
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    Osteosarcoma (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105060 , 9789535169642
    Language: English
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book is aimed at quickly updating the reader on osteosarcoma, a dreaded primary bone cancer. Progress in management of osteosarcoma has been slow after the evolution of chemotherapy and limb salvage surgery. Research is now directed towards identifying molecular targets for systemic therapy. Availability of chemotherapy drugs and low cost implants in developing world have allowed limb salvage surgery to develop. This book looks at current basic knowledge on osteosarcoma and some of the developments in research which have the potential to change the prognosis
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  • 37
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    Atherogenesis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079929 , 9789535167846
    Language: English
    Pages: 1 Online-Ressource (584 p.)
    Keywords: Cardiovascular medicine
    Abstract: This monograph will bring out the state-of-the-art advances in the dynamics of cholesterol transport and will address several important issues that pertain to oxidative stress and inflammation. The book is divided into three major sections. The book will offer insights into the roles of specific cytokines, inflammation, and oxidative stress in atherosclerosis and is intended for new researchers who are curious about atherosclerosis as well as for established senior researchers and clinicians who would be interested in novel findings that may link various aspects of the disease
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  • 38
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    Cardiomyopathies : From Basic Research to Clinical Management (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078342 , 9789535167099
    Language: English
    Pages: 1 Online-Ressource (816 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiomyopathy means "heart (cardio) muscle (myo) disease (pathy)". Currently, cardiomyopathies are defined as myocardial disorders in which the heart muscle is structurally and/or functionally abnormal in the absence of a coronary artery disease, hypertension, valvular heart disease or congenital heart disease sufficient to cause the observed myocardial abnormalities. This book provides a comprehensive, state-of-the-art review of the current knowledge of cardiomyopathies. Instead of following the classic interdisciplinary division, the entire cardiovascular system is presented as a functional unity, and the contributors explore pathophysiological mechanisms from different perspectives, including genetics, molecular biology, electrophysiology, invasive and non-invasive cardiology, imaging methods and surgery. In order to provide a balanced medical view, this book was edited by a clinical cardiologist
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  • 39
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    Aspects of Pacemakers : Functions and Interactions in Cardiac and Non-Cardiac Indications (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076164 , 9789535164883
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Cardiovascular medicine
    Abstract: Outstanding steps forward were made in the last decades in terms of identification of endogenous pacemakers and the exploration of their controllability. New "artifical" devices were developed and are now able to do much more than solely pacemaking of the heart. In this book different aspects of pacemaker - functions and interactions, in various organ systems were examined. In addition, various areas of application and the potential side effects and complications of the devices were discussed
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  • 40
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    Establishing Better Standards of Care in Doppler Echocardiography, Computed Tomography and Nuclear Cardiology (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533073668 , 9789535164357
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Cardiovascular medicine
    Abstract: Since the introduction of Doppler Echocardiography, Nuclear Cardiology and Coronary CT imaging, clinicians and researchers have been searching for ways to improve their use of these important tools in both the diagnosis and treatment of heart disease. To keep up with cutting edge improvements in these fields, experts from around the world have come together in this book to provide the reader with the most up to date information to explain how, why and when these different non-invasive imaging tools should be used. This book will not only serve its reader well today but well into the future
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  • 41
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    Modern Pacemakers : Present and Future (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533072142 , 9789535164234
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Cardiovascular medicine
    Abstract: The book focuses upon clinical as well as engineering aspects of modern cardiac pacemakers. Modern pacemaker functions, implant techniques, various complications related to implant and complications during follow-up are covered. The issue of interaction between magnetic resonance imaging and pacemakers are well discussed. Chapters are also included discussing the role of pacemakers in congenital and acquired conduction disease. Apart from pacing for bradycardia, the role of pacemakers in cardiac resynchronization therapy has been an important aspect of management of advanced heart failure. The book provides an excellent overview of implantation techniques as well as benefits and limitations of cardiac resynchronization therapy. Pacemaker follow-up with remote monitoring is getting more and more acceptance in clinical practice; therefore, chapters related to various aspects of remote monitoring are also incorporated in the book. The current aspect of cardiac pacemaker physiology and role of cardiac ion channels, as well as the present and future of biopacemakers are included to glimpse into the future management of conductions system diseases. We have also included chapters regarding gut pacemakers as well as pacemaker mechanisms of neural networks. Therefore, the book covers the entire spectrum of modern pacemaker therapy including implant techniques, device related complications, interactions, limitations, and benefits (including the role of pacing role in heart failure), as well as future prospects of cardiac pacing
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  • 42
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    Aneurysmal Disease of the Thoracic and Abdominal Aorta (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533075785 , 9789535166146
    Language: English
    Pages: 1 Online-Ressource (238 p.)
    Keywords: Cardiovascular medicine
    Abstract: The first successful open surgical repair of an abdominal aortic aneurysm was in 1951 by Dubost and represented a tremendous milestone in the care of this challenging disease. The introduction of endovascular repair in 1991 by Parodi furthered the care of these patients by allowing for lower morbidity and mortality rates and also, enabling surgeons to extend surgical treatment to patients traditionally deemed too high of a surgical risk. This new book on Aortic Disease covers many interesting and vital topics necessary for both the practicing surgeon as well as a student of vascular disease. The book starts with background information on the evolution of aortic management from traditional open surgical repair to modern endovascular therapies. There is also a chapter covering the data supporting current treatment modalities and how these data have supported modern management. Also, the use of endovascular means for care of the challenging situation of ruptured aneurysms is discussed. In addition to management of abdominal aneurysm, there is a chapter on treatment of aneurysms of the ascending aorta. Along with surgical treatment, one must also understand the molecular basis for how blood vessels remodel and thus, the role of cathepsins in aortic disease is elucidated. Lastly, chapters discussing the perioperative management of radiation exposure and ultrasound-guided nerve blocks as well as the need for high-quality postoperative nutrition will lend well to a full understanding of how to management patients from presentation to hospital discharge. We hope you enjoy this book, its variety of topics, and gain a fuller knowledge of Aneurysmal Disease of the Thoracic and Abdominal Aorta
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  • 43
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    Cardiac Defibrillation : Prediction, Prevention and Management of Cardiovascular Arrhythmic Events (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076928 , 9789535165675
    Language: English
    Pages: 1 Online-Ressource (190 p.)
    Keywords: Cardiovascular medicine
    Abstract: Millions of people throughout the world currently depend on appropriate, timely shocks from implantable cardioverter defibrillators (ICDs) to avoid sudden death due to cardiovascular malfunctions. Therefore, information regarding the use, applications, and clinical relevance of ICDs is imperative for expanding the body of knowledge used to prevent and manage fatal cardiovascular behavior. As such, the apt and timely research contained in this book will prove both relevant to current ICD usage and valuable in helping advance ICD technology. This book is divided into three comprehensive sections in order to cover several areas of ICD research. The first section introduces defibrillator technology, discusses determinants for successful defibrillation, and explores assessments of patients who receive defibrillation. The next section talks about predicting, preventing, and managing near catastrophic cardiovascular events, and research presented in the final section examine special cases in ICD patients and explore information that can be learned through clinical trial examinations of patients with defibrillators. Each chapter of this book will help answer critical questions about ICDs
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  • 44
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    Myocarditis (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533072890 , 9789535165293
    Language: English
    Pages: 1 Online-Ressource (442 p.)
    Keywords: Cardiovascular medicine
    Abstract: Myocarditis, the inflammation of the heart muscle, could be in some cases serious and potentially fatal disease. This book is a comprehensive compilation of studies from leading international experts on various aspects of myocarditis. The first section of the book provides a clinical perspective on the disease. It contains comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment. It also includes reviews of Perimyocarditis; Chagas' chronic myocarditis, and myocarditis in HIV-positive patients. The second section of the book focuses on the pathogenesis of myocarditis, discussing pathways and mechanisms activated during viral infection and host immune response during myocarditis. The third, and final, section discusses new findings in the pathogenesis that may lead to new directions for clinical diagnosis, including use of new biomarkers, and new treatments of myocarditis
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  • 45
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    Vasculogenesis and Angiogenesis : from Embryonic Development to Regenerative Medicine (2011)
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    ISBN: 9789533078823 , 9789535167471
    Language: English
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Cardiovascular medicine
    Abstract: Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood vessels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. The study of blood vessel formation is an essential component of embryonic development, congenital malformations, degenerative diseases, inflammation and cancer and thus has widespread appeal to the biomedical field. Moreover, scientists are now harnessing this information for the purpose of building living blood vessel substitutes for replacement of diseased arteries and veins. This book highlights novel advances in the field of vasculogenesis and angiogenesis, including embryogenesis and development, regulation of progenitor cells, cancer and blood vessel regeneration. We consider this book a good initial source of information for graduate students, medical students and scientists interested in the intricacies of blood vessel formation, maturation, disease and replacement
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  • 46
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    Angina Pectoris (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533073590 , 9789535165170
    Language: English
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Cardiovascular medicine
    Abstract: Angina is the most common disorder affecting patients with ischemic heart disease. This book provides a thorough review of fundamental principles of diagnosis, pathophysiology and treatment of angina pectoris, representing an invaluable resource not only for cardiologists, but also for general practitioners and medical students
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  • 47
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    Ventricular Assist Devices (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533071640 , 9789535164319
    Language: English
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Cardiovascular medicine
    Abstract: The assist devices will continue adding a large number of years of life to humans globally and empower the medical society to optimize heart failure therapy. While expensive and cumbersome task, the foundation provided in this book reflects a contemporary product of original research from a multitude of different experts in the field. We hope this cumulative international effort provides the necessary tools for both the novice as well as the active practitioner aiming to change the outcome of these complex patients
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  • 48
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    Cardiac Pacemakers : Biological Aspects, Clinical Applications and Possible Complications (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076393 , 9789535164678
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Cardiovascular medicine
    Abstract: Clinical usage of artificial pacing dates back to 1958, when the battery powered cardiac pacemakers became available. Modern implantable pacemakers are the complicated electronic devices operating 10 years continuously without battery exchange. Though the development of devices is not a primary topic of the book, certain efforts towards developing of biologic pacemakers through tissue engineering and studying of cell synchronization are discussed. The main attention is paid to implementations of pacemakers in different medical situations oriented towards widening the clinical indications for implanting the cardiac pacemakers. New methods and devices in cardiac resynchronization therapy (CRT) have received particular attention. Placing of pacing electrodes has been treated soundly. Furthermore, emerging of complexities and complications in new clinical situations and other safety problems have been discussed thoroughly. The authors have derived the used information from their own clinical practice and experiences of their medical colleagues. These and other pragmatic features can be acknowledged as the most valuable asset of the book
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  • 49
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    Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533075235 , 9789535164401
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book considers mainly etiology, pathogenesis, and pathophysiology of aortic aneurysms (AA) and aneurysm rupture and addresses anyone engaged in treatment and prevention of AA. Multiple factors are implicated in AA pathogenesis, and are outlined here in detail by a team of specialist researchers. Initial pathological events in AA involve recruitment and infiltration of leukocytes into the aortic adventitia and media, which are associated with the production of inflammatory cytokines, chemokine, and reactive oxygen species. AA development is characterized by elastin fragmentation. As the aorta dilates due to loss of elastin and attenuation of the media, the arterial wall thickens as a result of remodeling. Collagen synthesis increases during the early stages of aneurysm formation, suggesting a repair process, but resulting in a less distensible vessel. Proteases identified in excess in AA and other aortic diseases include matrix metalloproteinases (MMPs), cathepsins, chymase and others. The elucidation of these issues will identify new targets for prophylactic and therapeutic intervention
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  • 50
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    Diagnosis, Screening and Treatment of Abdominal, Thoracoabdominal and Thoracic Aortic Aneurysms (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533074665 , 9789535164784
    Language: English
    Pages: 1 Online-Ressource (426 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book considers mainly diagnosis, screening, surveillance and treatment of abdominal, thoracoabdominal and thoracic aortic aneurysms. It addresses vascular and cardiothoracic surgeons and interventional radiologists, but also anyone engaged in vascular medicine. The high mortality of ruptured aneurysms certainly favors the recommendation of prophylactic repair of asymptomatic aortic aneurysms (AA) and therewith a generous screening. However, the comorbidities of these patients and their age have to be kept in mind if the efficacy and cost effectiveness of screening and prophylactic surgery should not be overestimated. The treatment recommendations which will be outlined here, have to regard on the one hand the natural course of the disease, the risk of rupture, and the life expectancy of the patient, and on the other hand the morbidity and mortality of the prophylactic surgical intervention. The book describes perioperative mortality after endovascular and open repair of AA, long-term outcome after repair, and the cost-effectiveness of treatment
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  • 51
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    Cardiac Defibrillation : Mechanisms, Challenges and Implications (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076669 , 9789535165057
    Language: English
    Pages: 1 Online-Ressource (262 p.)
    Keywords: Cardiovascular medicine
    Abstract: The only known effective therapy for lethal disturbances in cardiac rhythm is de?brillation, the delivery of a strong electric shock to the heart. This technique constitutes the most important means for prevention of sudden cardiac death. The efficacy of defibrillation has led to an exponential growth in the number of patients receiving implantable devices. The objective of this book is to present contemporary views on the basic mechanisms by which the heart responds to an electric shock, as well as on the challenges and implications of clinical defibrillation. Basic science chapters elucidate questions such as lead configurations and the reasons by which a defibrillation shock fails. Chapters devoted to the challenges in the clinical procedure of defibrillation address issues related to inappropriate and unnecessary shocks, complications associated with the implantation of cardioverter/defibrillator devices, and the application of the therapy in pediatric patients and young adults. The book also examines the implications of defibrillation therapy, such as patient risk stratification, cardiac rehabilitation, and remote monitoring of patient with implantable devices
    Note: English
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  • 52
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    Coronary Angiography : The Need for Improvement in Medical and Interventional Therapy (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076416 , 9789535164739
    Language: English
    Pages: 1 Online-Ressource (220 p.)
    Keywords: Cardiovascular medicine
    Abstract: In this book we examined a periprocedural complication of coronary angiography, and coronary intervention. That includes related to cardiac catheterization and diagnostic coronary angiography, and those that occur as a consequence of the specific equipment. However, improvements in devices, the use of stents, and aggressive antiplatelet therapy have significantly reduced the incident of major periprocedural complications. This book giving knowledge and experiences many of interventional cardiologists from all over the world, and provide possibility to recognize new approach in this domain. Book gives lecture on how we image and how we decide on what to treat, how to treat it, and then results of that treatment. They offer many answers to what we have today and what we will have tomorrow
    Note: English
    URL: kostenfrei
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    Aortic Valve (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533075617 , 9789535166030
    Language: English
    Pages: 1 Online-Ressource (364 p.)
    Keywords: Cardiovascular medicine
    Abstract: Much has evolved in the field of aortic valve disease because of the increase in knowledge in the last decade, especially in the area of its management. This book "Aortic Valve" is comprised of 18 chapters covering basic science, general consideration of aortic valve disease, infective endocarditis, aortic sclerosis and aortic stenosis, bioprosthetic valve, transcatheter aortic valve implantation and a special section on congenital anomalies of the aortic valve. We hope this book will be particularly useful to cardiologists and cardiovascular surgeons and trainees. We also believe that this book will be a valuable resource for radiologists, pathologists, cardiovascular anesthesiologists, and other healthcare professionals who have a special interest in treating patients with aortic valve disease. We are certain that information in this book will help to provide virtually most new areas of aortic valve disease that will be employed in the current era
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 54
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    Online Resource
    Advances in the diagnosis of coronary atherosclerosis (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen | Rijeka : Intech d.o.o.
    Details
    ISBN: 9789535165613
    Language: English
    Pages: 1 Online-Ressource (XI, 378 Seiten) , Illustrationen, Diagramme
    Keywords: Cardiovascular medicine ; Aufsatzsammlung
    Abstract: Coronary artery disease (CAD) and its consequences are most important morbidity and mortality reasons in the developed and developing countries. To prevent hard end-points, early definitive diagnosis and optimum therapy play significant role. Novel advanced diagnostic tests which are biomarkers of inflammation, cell adhesion, cell activation and imaging techniques provide to get the best result in the detection and characterization of calcified or uncalcified atherosclerotic plaques. In spite of last developments in the imaging methods, coronary catheterization is still frequently performed. Following the first cardiac catheterization performed in 1844, date by date historical developments and the mechanics of cardiac catheterization techniques, risks associated with coronary angiography, and also, preventions and treatments of possible complications have been presented in this book. Other important issue is radiation exposure of patients and staff during coronary angiography and scintigraphy. Radiation dose reduction techniques, general radiation protection principles have been discussed in related chapters
    Note: Literaturangaben
    DOI: 10.5772/790
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  • 55
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    Coronary Angiography : Advances in Noninvasive Imaging Approach for Evaluation of Coronary Artery Disease (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076751 , 9789535164852
    Language: English
    Pages: 1 Online-Ressource (428 p.)
    Keywords: Cardiovascular medicine
    Abstract: In the intervening 10 years tremendous advances in the field of cardiac computed tomography have occurred. We now can legitimately claim that computed tomography angiography (CTA) of the coronary arteries is available. In the evaluation of patients with suspected coronary artery disease (CAD), many guidelines today consider CTA an alternative to stress testing. The use of CTA in primary prevention patients is more controversial in considering diagnostic test interpretation in populations with a low prevalence to disease. However the nuclear technique most frequently used by cardiologists is myocardial perfusion imaging (MPI). The combination of a nuclear camera with CTA allows for the attainment of coronary anatomic, cardiac function and MPI from one piece of equipment. PET/SPECT cameras can now assess perfusion, function, and metabolism. Assessing cardiac viability is now fairly routine with these enhancements to cardiac imaging. This issue is full of important information that every cardiologist needs to now
    Note: English
    URL: kostenfrei
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  • 56
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    New Aspects of Ventricular Assist Devices (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076768 , 9789535164630
    Language: English
    Pages: 1 Online-Ressource (144 p.)
    Keywords: Cardiovascular medicine
    Abstract: Ventricular assist device has become one of the standard therapies for the support and the management of the failing heart. Updating our knowledge about these devices is mandatory in order to improve patient outcomes. In this book we can read the efforts made by many physicians concerned with the treatment of heart failure with mechanical devices. We all hope that the information compiled by experts in ventricle assist devices in this book will help us all to do better our main task - heal patients
    Note: English
    URL: kostenfrei
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  • 57
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    Atherosclerotic Cardiovascular Disease (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076959 , 9789535165149
    Language: English
    Pages: 1 Online-Ressource (134 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular diseases (CVD) are still one of the leading causes of death in the world. The book Atherosclerotic Cardiovascular Disease is a contribution to the application of new knowledge in the area of cardiovascular diseases. The book comprises six chapters divided in three subsections, starting with the General Considerations of Cardiovascular Disease, through Diagnostic Techniques, and Specific Therapy
    Note: English
    URL: kostenfrei
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