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  • 2010-2014  (139)
  • 2005-2009
  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (139)
  • Endocrinology  (82)
  • Cardiovascular medicine  (57)
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Material
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Year
Author, Corporation
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  • 1
    Online Resource
    Online Resource
    Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tract : from Bench to Bedside (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535116318 , 9789535172192
    Language: English
    Pages: 1 Online-Ressource (380 p.)
    Keywords: Endocrinology
    Abstract: The capsaicin, a component of paprika, has been used in the culinary practice of every day nutritional practice. This agent is known to cause a variety of actions in the body through activating capsaicin-sensitive afferent neurons. A recently launched book entitled, Capsaicin-Sensitive Neural Afferentation and the Gastrointestinal Tract: from Bench to Bedside, is attractive for several reasons. First, Prof. Mozsik, a chief editor of this book, is known internationally as an expert in capsaicin pharmacology. Since he has worked for many years as a head of internal medicine, taking care of patients with various GI diseases, he is able to make a correct interpretation of various findings obtained in basic researches to clinical events. Second, although there are many articles about capsaicin, they mostly deal with basic research and finding but do not include much about clinical finding. Third, this book encompassed review articles written by internationally accepted scientists leading the field of capsaicin research, who highlighted the current state of knowledge on pharmacology, physiology and clinical phathophysiology of capsaicin-sensitive afferent neurons, and discussed directions for future research. Overall, this book is for people who are interested in the capsaicin action in body
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 2
    Online Resource
    Online Resource
    Glucose Homeostasis (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535116189 , 9789535172123
    Language: English
    Pages: 1 Online-Ressource (176 p.)
    Keywords: Endocrinology
    Abstract: Most tissues and organs, such as the brain, need glucose constantly, as an important source of energy. The low blood concentrations of glucose (hypoglycemia) can cause seizures, loss of consciousness, and death. On the other hand, long lasting elevation of blood glucose concentrations (hyperglycemia) can result in blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Therefore, blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady-state level is called glucose homeostasis. This is accomplished by the finely hormone regulation of peripheral glucose uptake (glucose utilization), hepatic glucose production and glucose uptake during carbohydrates ingestion
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 3
    Online Resource
    Online Resource
    Trends in Helicobacter pylori Infection (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112396 , 9789535172000
    Language: English
    Pages: 1 Online-Ressource (392 p.)
    Keywords: Endocrinology
    Abstract: Helicobacter pylori is a universally distributed bacterium which affects more than half of the world population. The infection is associated with the development of various diseases of the upper gastrointestinal tract, besides extradigestive diseases. This book is a comprehensive overview of contributors on H. pylori infection in several areas. Its chapters were divided into sections concerning general aspects of H. pylori infection, immunopathology and genetic diversity, questions regarding possible routes of bacterium transmission, the importance of the strains characteristics in the development of gastric cancer and the possibilities of prevention, H. pylori infection in children, the possible association between its infection and extradigestive diseases, and the principal therapeutic regimens of bacterium eradication, considering the antimicrobial resistance
    Note: English
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    MPI Ethno. Forsch.
  • 4
    Online Resource
    Online Resource
    Carotid Artery Disease : From Bench to Bedside and Beyond (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112143 , 9789535171898
    Language: English
    Pages: 1 Online-Ressource (232 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book will bring out the state of art of carotid stenosis in the basic and clinical approaches for better understanding of the mechanisms and useful therapies for these disease. We hope that would be a new current trend understanding new aspects regarding this scientific problematic involving not only anatomical, functional but also clinical questions
    Note: English
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  • 5
    Online Resource
    Online Resource
    Thyroid Disorders : Focus on Hyperthyroidism (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535113843 , 9789535172062
    Language: English
    Pages: 1 Online-Ressource (280 p.)
    Keywords: Endocrinology
    Abstract: The thyroid disorders are one of the most common and exciting areas of endocrinology. Hypothyroidism, multinodular goiter, hyperthyroidism and thyroid cancer are only few of the several implications that the thyroid disorders have in health. In fact, thyroid hormones regulate not only metabolism process, but also many other molecular and physiological systems. From this point of view, hyperthyroidism complications are a good example of the significance of thyroid hormone actions. This book aims to provide a general view of thyroid disorders, and a deeper explanation of hyperthyroidism and its complications and impact in health
    Note: English
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  • 6
    Online Resource
    Online Resource
    Fecal Incontinence : Causes, Management and Outcome (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112419 , 9789535172024
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Fecal incontinence is a common and disabling condition that unfortunately remains an “orphan” in terms of medical research and effective therapies. This book provides a brief review of the pathophysiology of fecal incontinence with specific focus on women and children. Authorship is drawn internationally, with a strong surgical input. Contributions from the authors provide critical reviews of the evaluation of function, with illustrations of a range of surgical interventions which might be applied should medical therapies fail
    Note: English
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  • 7
    Online Resource
    Online Resource
    Antioxidant-Antidiabetic Agents and Human Health (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112150 , 9789535171904
    Language: English
    Pages: 1 Online-Ressource (382 p.)
    Keywords: Endocrinology
    Abstract: The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases
    Note: English
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  • 8
    Online Resource
    Online Resource
    Aortic Aneurysm : Recent Advances (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110811 , 9789535171263
    Language: English
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Endocrinology
    Abstract: An increase in aortic aneurysm occurrence is registered, despite considerable advances in surgical interventions. Consequently, numerous researchers have been trying to improve the understanding the aortic aneurysm pathogenesis in order to facilitate an early diagnosis, to identify new therapeutic targets, and to develop complex therapies. Within this book, the reader may find interesting data about etiology, risk factors, and pathogenesis of aortic aneurysm, its characteristics in young age, particularities of aneurysms affecting visceral arteries, the preoperative evaluation of the patients, different perspectives regarding the surgical therapy, including the treatment of complications after prior surgery, original proposals regarding new therapeutic modalities, and advanced imaging strategies. The multidisciplinary team of authors provides an interesting lecture and an update of the scientific literature
    Note: English
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  • 9
    Online Resource
    Online Resource
    Gonadotropin (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110064 , 9789535170938
    Language: English
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Endocrinology
    Abstract: This is a must-have book for those interested in reproduction. It provides a full account of our current knowledge of the hormones intimately associated with testicular and ovarian function. Each chapter is carefully organized to cover basic concepts and recent advances in gonadotropin synthesis and secretion. The information is presented in a sequence that provides researchers, teachers, and students with a logical integration of the reproductive axis. Practical applications associated with reproductive management of domestic species are also provided. Taken together, this book is a comprehensive combination of fundamental endocrine concepts and original findings in the area of gonadotropin function
    Note: English
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  • 10
    Online Resource
    Online Resource
    Gestational Diabetes : Causes, Diagnosis and Treatment (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110774 , 9789535171348
    Language: English
    Pages: 1 Online-Ressource (174 p.)
    Keywords: Endocrinology
    Abstract: This book summarizes several aspects of GD, which is caused by not well-understood multifactorial mechanisms. Common strategies seem to be key in the understanding of the syndrome, i.e., endothelial dysfunction and the role of other placenta cells such as trophoblasts. It is a book that will definitively help to increase the knowledge-based management of GD for the well being of the mother and the fetus. Several chapters lead us to the conclusion that pre-pregnancy and antenatal screening of women is required, something that will improve the management and outcome of a current pregnancy but will also optimize life-long health and well being considering the inter-generational consequences
    Note: English
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  • 11
    Online Resource
    Online Resource
    Arteriovenous Fistulas : Diagnosis and Management (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111788 , 9789535171720
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Cardiovascular medicine
    Abstract: Arteriovenous fistulas are shunts between arteries and veins that can be found in many organs of the human body such as the brain, skin, eye and lung. These lesions can be symptomatic by causing ischemia, through the process of the steal phenomenon, or vascular congestion and subsequent hemorrhage, eg. intracerebral hemorrhage of a ruptured dural arteriovenous fistula. The etiology of these lesions is not fully understood, some are congenital and others are acquired. On the other hand, iatrogenic arteriovenous fistulas, such as in hemodialysis patients, can be a life-saving procedure. This book provides a clear and concise review of the diagnosis and management of arteriovenous fistulas throughout the human body. It could be a great resource to medical students, residents, fellows, professors and researchers in the field
    Note: English
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  • 12
    Online Resource
    Online Resource
    Gastric Carcinoma : New Insights into Current Management (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109143 , 9789535170679
    Language: English
    Pages: 1 Online-Ressource (306 p.)
    Keywords: Endocrinology
    Abstract: Gastric cancer is the second most common cause of cancer-related death in the world. There are no screening tests available for its diagnosis, therefore patients usually presents in late stages, associated with poor prognosis. Currently, many efforts are made toward new advances in the treatment strategies. The book makes an insight into the assessment of premalignant lesions, current management of early gastric cancer, risk and protective factors in gastric carcinogenesis. "Gastric cancer" provides a detailed description of the morphologic classification, molecular changes and epigenetic alterations of this tumor. The book describes the role of different diagnostic tools in the preoperative assessment of patients and the most important factors contributing to the prognosis. Moreover, it describes the current surgical and chemotherapeutic options for gastric neoplasm. This publication may open new and interesting gates for further research concerning carcinogenesis, genetic and epigenetic alterations, signaling pathways, H. pylori infection, the discovery of protective factors against gastric cancer and of revolutionary therapies of this tumor
    Note: English
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  • 13
    Online Resource
    Online Resource
    Current Topics in Hypothyroidism with Focus on Development (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109709 , 9789535170846
    Language: English
    Pages: 1 Online-Ressource (232 p.)
    Keywords: Endocrinology
    Abstract: Do you regard hypothyroidism as a more complex issue than just a simple prescription of levothyroxine tablet? Are you interested in getting more information on the management of thyroid dysfunction in pregnancy, at birth, in childhood or in subclinical states? Have you been thinking of performing thyroid ultrasound in hypothyroid patients by yourself, or perhaps you already do it and are not so sure about it? Than this book should give you some answers and help you form your own opinion. You will find there several excellent review articles from authors from all over the world
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  • 14
    Online Resource
    Online Resource
    Calcific Aortic Valve Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111504 , 9789535171638
    Language: English
    Pages: 1 Online-Ressource (542 p.)
    Keywords: Cardiovascular medicine
    Abstract: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future
    Note: English
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  • 15
    Online Resource
    Online Resource
    Type 1 Diabetes (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110170 , 9789535171027
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Endocrinology
    Abstract: This book contains a series of up-to-date chapters that review our current knowledge of type 1 diabetes as an autoimmune disease, the problems that still remain with existing treatments, and possible solutions for the near future
    Note: English
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  • 16
    Online Resource
    Online Resource
    Cardiomyopathies (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111030 , 9789535171614
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Cardiovascular medicine
    Abstract: The disease of the heart muscle may occur secondarily to common diseases, such as ischemic, hypertensive and valvular, among others. However, there is a group of conditions with intrinsic myocardial involvement from gene or multifactorial etiology, and high morbidity and mortality that represent a diagnostic and therapeutic challenge for the physician. The book is focused on these cardiomyopathies, its features, its pathophysiology and its relation to sudden death. Mention is made also on general aspects, like ecocardiographic findings and myocardial contractile reserve, specific as pathophysiology and molecular mechanisms and cardiomyopathies in special populations. Special attention was deserved to cardiomyopathies in pediatrics, diabetic patients and women, as well as to the cases of chronic heart failure and dilated cardiomyopathy
    Note: English
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  • 17
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    What Should We Know About Prevented, Diagnostic, and Interventional Therapy in Coronary Artery Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535110439 , 9789535171164
    Language: English
    Pages: 1 Online-Ressource (484 p.)
    Keywords: Cardiovascular medicine
    Abstract: The mortality from ischemic heart disease has decreased in recent years. The better understanding of risk factors associated with development of coronary artery disease has significantly contributed to this decline. Improvements in medical and interventional therapy have reduced the complications associated with acute myocardial infarction as well as revascularization. After the introduction of imaging modalities, the noninvasive characterization of regional function, perfusion and metabolism allowed for more sophisticated tissue characterization to identify reversible dysfunction with high diagnostic and prognostic accuracy. We now can legitimately claim that computed tomography angiography (CTA) of the coronary arteries is available. In the evaluation of patients with suspected coronary artery disease, many guidelines today consider CTA an alternative to stress testing. However the nuclear technique most frequently used by cardiologists is myocardial perfusion imaging (MPI). The combination of a nuclear camera with CTA allows for the attainment of coronary anatomic, cardiac function and MPI from one piece of equipment. Assessing cardiac viability is now fairly routine with these enhancements to cardiac imaging. Traditional coronary angiography presents a variety of limitations related to image acquisition, content, interpretation, and patient safety. Barriers to such improvements include the paucity of clinical outcomes studies related to new imaging technology, the need for physician and staff member training, and the costs associated with acquiring and effectively using these advances in coronary angiography. This issue is full of important information that every cardiologist needs to now
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  • 18
    Online Resource
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    Current Topics in Gastritis : 2012 (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109075 , 9789535170631
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Endocrinology
    Abstract: Gastritis, as a medical term, exists for the last 150 years, however, terminology and etiology (including the prognosis ) has changed. Gastritis related medical problems are in the focus of different sub-disciplines: internists , gastroenterologists, pathologists, immunologists, bacteriologists, genetics, biologists etc. After the publications by Marshall and Warren most of the clinicians accepted only the etiopathological role of Helicobacter pylori in the development of gastric and duodenal ulcer , as well as in the gastric cancer. This book presents chapters abou the history of gastritis terminology, animal models, epidemiology, new gastric mucosal endogenous defensive neural mechanism (capsaicin-sinsitive afferentation), different research and clinical methods applied to the background studies and the molecular pathology, biochemistry and genetics involved in the pathways from Helicobacter pylori infection to development of gastric cancer. Intended audience of this book are internists, gastroenterologists, pathologists, bacteriologists, pharmacologists, genetics, biologists , immunologists and other interested researchers
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  • 19
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    Lipid Metabolism (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109440 , 9789535170747
    Language: English
    Pages: 1 Online-Ressource (474 p.)
    Keywords: Endocrinology
    Abstract: Lipids (fats and oils) are a wide range of organic molecules that serve several functions in organisms. Lipids are essential components of our diet, highlighting their important contribution in energy, representing 9 kcal/g (or 37.7 kJ/g), and by some components relevant to the metabolism, such as essential fatty acids, fat soluble vitamins and sterols (cholesterol and phytosterols). Besides this, lipids have key roles in human growth and development, along with promoting, preventing and/or participating in the origin or eventually in the treatment of various diseases. This book presents a systematic and comprehensive review about the structure and metabolism of lipids, particularly highlighting the importance of these molecules in the body and considering the interest of some lipids in health and disease
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  • 20
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    Atrial Fibrillation : Mechanisms and Treatment (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110231 , 9789535171041
    Language: English
    Pages: 1 Online-Ressource (248 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atrial fibrillation is a rapidly evolving epidemic associated with increased cardiovascular morbidity and mortality, and its prevalence has increased over the past few decades. In the past few years, the recent understanding of the diverse mechanisms of this arrhythmia has lead to the improvement of our therapeutic strategies. However, many clinicians have still felt the frustration in management of this commonly encountered arrhythmia. This book contains a spectrum of different topics from bench to bedside in atrial fibrillation. We strongly believe that scientists, cardiologists and electrophysiologists will find this book very informative and useful and the references cited in each chapter will definitely act as an additional source of information for readers
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  • 21
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    Recent Advances in Infective Endocarditis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111696 , 9789535171690
    Language: English
    Pages: 1 Online-Ressource (134 p.)
    Keywords: Cardiovascular medicine
    Abstract: Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery
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  • 22
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    Ischemic Heart Disease (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109938 , 9789535170921
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular disease (CVD) is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. A coronary even occurs every 25 seconds and CVD kills one person every 34 seconds. 35 people under 65 years of age die prematurely every day due to CVD. The incidence of CVD has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy, new drug regimens and advances in acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text reviews the epidemiology, development, risk factors, diagnosis and treatment of ischemic heart disease
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  • 23
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    Diabetes Mellitus : Insights and Perspectives (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109396 , 9789535170723
    Language: English
    Pages: 1 Online-Ressource (348 p.)
    Keywords: Endocrinology
    Abstract: The fundamental treatment and management goals in diabetes mellitus are to control and normalize blood glucose levels and to prevent diabetic complications. It also includes maintaining normal growth and development and normal body weight. Proper diet, regular exercise, weight control and different therapeutic agents are the mainstays of diabetic care and management. Weight reduction and exercise have been shown to improve tissue sensitivity to insulin and allow its proper use by target tissues. It is obvious that medical management and goals of therapy for diabetes mellitus have changed since the publication of the Diabetes Control and Complications Trial in 1993. Recent studies have shown that the risk of developing retinopathy can decrease by 76% in properly managed diabetic patients when compared to control group and that clinical and laboratory signs and symptoms of nephropathy and neuropathy can also decrease by 54 to 60%. Modern approaches to the management of diabetes mellitus embrace holistic options and this book addressed various approaches in the management of diabetes mellitus
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  • 24
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    Artery Bypass (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535110255 , 9789535171126
    Language: English
    Pages: 1 Online-Ressource (548 p.)
    Keywords: Cardiovascular medicine
    Abstract: The latest diagnostic and therapeutic modalities in the management of coronary artery disease by coronary artery bypass graft surgery and by percutaneous coronary intervention with stenting and in the interventional management of other atherosclerotic vascular disease have led to a reduction in cardiovascular mortality and morbidity. This book entitled Artery Bypass provides an excellent update on these advances which every physician seeing patients with atherosclerotic vascular disease should be familiar with. This book includes 27 chapters written by experts in their topics
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  • 25
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    Type 2 Diabetes (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111719 , 9789535171676
    Language: English
    Pages: 1 Online-Ressource (546 p.)
    Keywords: Endocrinology
    Abstract: Type 2 diabetes is now a global serious health problem. Patients with type 2 diabetes have 2-4 times higher risk of cardiovascular and renal complications, morbidity and mortality. This book, Type 2 Diabetes, is a unique book covering the topics including pathophysiology, complications and prevention and treatments. Understanding the etiology of the onset and development of type 2 diabetes is important to prevent type 2 diabetes complications and delay the progress. The Pathophysiology section covers a wide range of mechanisms and characteristics from the micro (molecular) to the macro (neurohormonal mechanisms and the beta-cell function in the pancreas). The Complications section includes renal complications, sympathetic nervous system imbalance, atherosclerosis, and foot ulcers which are frequently observed in diabetic patients. Finally, the Prevention and Treatments section consists of non-pharmacological treatments, bariatric surgery, pharmacological therapy, and insulin therapy. The editor hopes that this book is helpful for your clinical practice and research, and this book facilitates the reduction of global burden of type 2 diabetes
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  • 26
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    Hot Topics in Echocardiography (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112044 , 9789535171850
    Language: English
    Pages: 1 Online-Ressource (148 p.)
    Keywords: Cardiovascular medicine
    Abstract: Echocardiography is still the most used imaging technique for the evaluation of cardiac anatomy and function and today it plays an essential role in daily decision making. The echocardiographic technology and its applications have widely developed in the last years leading to a better diagnostic accuracy. On the other hand echocardiography specialists have new clinical questions to answer. Echocardiography meets the growing need for non-invasive imaging in the expanding heart failure population and during structural heart interventions. The new percutaneous therapies need, a precise evaluation of cardiac dimensions and a complete understanding of the spatial relationships between cardiac structures. Echocardiography is of paramount importance both during the patient evaluation and guiding the procedure. This book tries to give an in depth evaluation about the specific issues that a modern cardiovascular imaging specialist is asked to answer nowadays
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  • 27
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    Dyspepsia : Advances in Understanding and Management (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112051 , 9789535171843
    Language: English
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Endocrinology
    Abstract: This textbook is specifically written for clinicians involved in managing patients with dyspepsia. It is a practical guide with up-to-date suggestions on evaluation, diagnosis, and management from experts from around the world. Each chapter is a succinct review of current topics that play a role in the pathogenesis and management of this disorder. Special populations such as pediatrics, those with cardiovascular disease and womens health are specifically examined
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  • 28
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    Hot Topics in Endocrine and Endocrine-Related Diseases (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110804 , 9789535171386
    Language: English
    Pages: 1 Online-Ressource (276 p.)
    Keywords: Endocrinology
    Abstract: This book covers a selected number of hot topics in endocrine and hormone-related pathologies, discussed by eminent scientists and clinicians coming from different countries of the world. It deals with advanced recent trends in the field, including neuroendocrine and pituitary tumors, thyroid dysfunctions, diabetes and a series of endocrine-related diseases, such as those related to the anabolic effects of testosterone, obesity, cancer, the liver complications of diabetes and the pediatric nonalcoholic fatty liver disease. The readers should be able to have a basic, as well as critic and advanced, overview of these selected hot pathologies of the endocrine system
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  • 29
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    Recent Advances in the Field of Ventricular Assist Devices (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535111115 , 9789535171423
    Language: English
    Pages: 1 Online-Ressource (104 p.)
    Keywords: Endocrinology
    Abstract: Recent Advances in the Field of Ventricular Assist Devices covers recent various advances and developments relating to ventricular assist devices and their diverse complications. Firstly, we overview recent technical advances as well as current indications, clinical outcomes, and countermeasures against complications, and furthermore, the latest techniques to identify clinical effectiveness at the patient’s bedside. Secondly, we elucidate the current status of countermeasures against gastrointestinal bleeding, and current research on allosensitization during the usage of continuous flow pump. Finally, we explore the possibility of a new adjunct therapy in combination with ventricular assist devices. We hope that this book will provide valuable and up-to-date information on research and clinical use of ventricular assist devices
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  • 30
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    Endoscopy of GI Tract (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110347 , 9789535171133
    Language: English
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Endocrinology
    Abstract: Endoscopy has had a major impact in the development of modern gastroenterology and other medical specialties. The field of endoscopic procedure has developed over the last decade. By using different data it provided a better understanding of pathogenic mechanisms, described new entities and used for early detection, diagnostic procedures and therapeutic procedures. The advantages of many technical advances and modern-endoscopic equipments, endoscopy has had a developed spectacularly. Furthermore, endoscopy has surpassed its function as an examination tool and it became a rapid and efficient therapeutic tool of low invasiveness. The efficacy and usefulness of endoscopy has yet been established
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  • 31
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    Research Directions in Tumor Angiogenesis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535109631 , 9789535170792
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Cardiovascular medicine
    Abstract: Angiogenesis is an extension process of the cardiovascular network within human body. It is usually triggered by the demand of oxygen and nutrients from the fast growing tissue and uncontrollably dividing cells, as seen during wound healing and tumor progression. This book focuses on tumor angiogenesis and includes 8 chapters written by highly experienced scholars from five different countries. It is the goal of this book to provide readers with an update on the molecular and cellular mechanisms of this biological process and hopefully to point out some new research directions for future therapeutic adventure
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  • 32
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    Diagnosis and Treatment of Myocarditis (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535110828 , 9789535171393
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Cardiovascular medicine
    Abstract: Myocarditis is a clinical syndrome, most frequently of infectious etiology, that occurs with a broad range of relatively non-specific symptoms, and consists of an inflammatory process of the heart with necrosis and degeneration of the myocardium by inflammatory infiltration of immune cells. The infection can cause direct injury of cardiomyocytes as well as immune-mediated destruction of the myocardium, leading to cardiac dysfunction. In this book, the broad aspects of myocarditis are fully presented by leading international experts. The texts are devoted to both clinical aspects and pathophysiology, and they present comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment, as well as myocarditis in special populations such as pediatric, peripartum and chronic chagasic myocarditis
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  • 33
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    Basic Cardiopulmonary Resuscitation Manual (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112013 , 9789535171867
    Language: Undetermined
    Pages: 1 Online-Ressource (82 p.)
    Keywords: Cardiovascular medicine
    Abstract: The purpose of this publication is to systematize the knowledge necessary to make Cardiopulmonary Resuscitation (CPR) or Cardiorespiratory Resuscitation (CRR) known to nursing health specialists, which translates as a set of temporary and internationally standardized maneuvers assigned to ensure the oxygenation of the vital organs when the blood circulation of an individual stops suddenly, independently of the cause of the Cardiorespiratory arrest (CRA). This knowledge is found correctly delimited in The Basic Cardiopulmonary Resuscitation Manual, which especially emphasizes the step-by-step methodology and techniques to follow for Cardiopulmonary Resuscitation (CPR). This is a basic work that cannot be overlooked by health care specialists, the society, and the public in general, because of the high probability that this situation will present at some moment in life. Thus, it is recommended to be prepared to help some person in an emergency situation. The manual is an excellent consultation work for health professionals. Given that what is expressed in this work is fundamental for life, and its objective is to make known the relevant information concerning the knowledge of CPR
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  • 34
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    Liver Biopsy : Indications, Procedures, Results (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535108535 , 9789535170440
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Endocrinology
    Abstract: Liver biopsy is a procedure that involves obtaining a small piece of liver tissue, which is then analyzed in the laboratory. Liver biopsy may be used to evaluate a mass seen on images, diagnose unexplained liver diseases or abnormal liver function tests, and to determine the severity of the liver disease including hepatitis, fibrosis, and steatosis. Liver biopsy is an invasive procedure, and its complications are rare but potentially lethal. Therefore, it is necessary to perform liver biopsy safely from clinical aspect and to take specimen steadily from a pathological one. I hope this book addresses the future aspects of liver biopsy including role, indication, technique and evaluation. Furthermore, this book introduces new non-invasive alternatives including elastography and computer analysis of liver fibrosis
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  • 35
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    Glucocorticoids : New Recognition of Our Familiar Friend (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535108726 , 9789535170464
    Language: English
    Pages: 1 Online-Ressource (660 p.)
    Keywords: Endocrinology
    Abstract: As one class of the most important steroid hormones, glucocorticoids have long been recognised and their therapeutic benefits have been widely used in clinical treatment, especially in anti-inflammation cases. Glucocorticoids regulate various processes in the body including the mobilization of energy stores, immune functions, gene expression, and maintenance of the homeostasis as well as the stress response, this is not surprising that the concept of "glucocorticoids" is mentioned in almost all medical text books that focus on specific organs or systems such as the cardiovascular system, the immune system, and the neuroendocrine system. The book of Glucocorticoids - New Recognition of Our Familiar Friend aims to introduce the latest findings relating to glucocorticoids, either freshly from the laboratory or from clinical case studies, and to open up a new angle of looking at the issue of balancing the therapeutic benefits and side effects brought up by glucocorticoids
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  • 36
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    Steroids : From Physiology to Clinical Medicine (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535108573 , 9789535170457
    Language: English
    Pages: 1 Online-Ressource (222 p.)
    Keywords: Endocrinology
    Abstract: Steroids - From Physiology to Clinical Medicine covers contemporary basic science on steroids research, along with steroids practical application in clinical medicine. We start by describing physiological and pathophysiological roles of steroids, with reference to production and action of gonadal steroids, role of steroid sulfonation, sex specific and steroids-dependent mechanism of hippocampal function, and the hydroxysteroid dehydrogenases for the modulation of tissue glucocorticoid availability. We then covered different aspects of steroids application in clinical environment, such as endocrine function after ovarian transplantation, diagnostic significance of salivary assessment of androgens, drawbacks of steroids use in sport, analysis of serum steroid hormone profiles in patients with adrenocortical tumors, and correlation between salivary and serum cortisol responses after alcohol intake. In response to the need to address novel and valuable information on steroids science and medicine, we sincerely hope that this book will enable readers to comprehend this fast-growing and exciting scientific discipline
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  • 37
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    Current Issues and Recent Advances in Pacemaker Therapy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107033 , 9789535170235
    Language: English
    Pages: 1 Online-Ressource (300 p.)
    Keywords: Cardiovascular medicine
    Abstract: Patients with implanted pacemakers or defibrillators are frequently encountered in various healthcare settings. As these devices may be responsible for, or contribute to a variety of clinically significant issues, familiarity with their function and potential complications facilitates patient management. This book reviews several clinically relevant issues and recent advances of pacemaker therapy: implantation, device follow-up and management of complications. Innovations and research on the frontiers of this technology are also discussed as they may have wider utilization in the future. The book should provide useful information for clinicians involved in the management of patients with implanted antiarrhythmia devices and researchers working in the field of cardiac implants
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  • 38
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    New Advances in the Basic and Clinical Gastroenterology (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535105213 , 9789535169666
    Language: English
    Pages: 1 Online-Ressource (568 p.)
    Keywords: Endocrinology
    Abstract: The purpose of this book was to present the integrative, basic and clinical approaches based on recent developments in the field of gastroenterology. The most important advances in the pathophysiology and treatment of gastrointestinal disorders are discussed including; gastroesophageal reflux disease (GERD), peptic ulcer disease, irritable bowel disease (IBD), NSAIDs-induced gastroenteropathy and pancreatitis. Special focus was addressed to microbial aspects in the gut including recent achievements in the understanding of function of probiotic bacteria, their interaction with gastrointestinal epithelium and usefulness in the treatment of human disorders. We hope that this book will provide relevant new information useful to clinicians and basic scientists as well as to medical students, all looking for new advancements in the field of gastroenterology
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  • 39
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    Coronary Interventions (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535104988 , 9789535169604
    Language: English
    Pages: 1 Online-Ressource (254 p.)
    Keywords: Cardiovascular medicine
    Abstract: Given the prevalence of heart conditions in modern populations, new techniques for treating patients are highly warranted. This book will be required reading for researchers and healthcare practitioners, as it offers assessments of complications, the new transradial approach and an overview of drug-eluting stents. A special focus on percutaneous coronary interventions is evident, from chapters on pharmacotherapy, its relevance to 30-day mortality and the CANADA score, besides the treatment of patients with saphenous vein graft disease. Other treatment protocols addressed include therapeutic hypothermia and the drug-eluting balloon, cardiac postconditioning to limit cell death following myocardial infarction and rotablation in the drug-eluting Syent era. There is also a chapter on using contrast medium-induced nephropathy gram-iodine/GFR ratio to predict CIN
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  • 40
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    Oxidative Stress and Diseases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535105527 , 9789535152828
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Cardiovascular medicine
    Abstract: The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pathologies in humans and animals. The chapters are organized into sections based on specific groups of pathologies such as cardiovascular diseases, diabetes, cancer, neuronal, hormonal, and systemic ones. A special section highlights potential of antioxidants to protect organisms against deleterious effects of reactive species. This book should appeal to many researchers, who should find its information useful for advancing their fields
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  • 41
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    Cardiovascular Risk Factors (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102403 , 9789535168812
    Language: English
    Pages: 1 Online-Ressource (506 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular risk factors contribute to the development of cardiovascular disease from early life. It is thus crucial to implement preventive strategies addressing the burden of cardiovascular disease as early as possible. A multidisciplinary approach to the risk estimation and prevention of vascular events should be adopted at each level of health care, starting from the setting of perinatology. Recent decades have been marked with major advances in this field, with the emergence of a variety of new inflammatory and immune-mediated markers of heightened cardiovascular risk in particular. The current book reflects some of the emerging concepts in cardiovascular pathophysiology and the shifting paradigm of cardiovascular risk estimation. It comprehensively covers primary and secondary preventive measures targeted at different age and gender groups. Attention is paid to inflammatory and metabolic markers of vascular damage and to the assessment of vascular function by noninvasive standardized ultrasound techniques. This is a must-read book for all health professionals and researchers tackling the issue of cardiovascular burden at individual and community level. It can also serve as a didactic source for postgraduate medical students
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  • 42
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    Acute Pancreatitis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533079844 , 9789535167792
    Language: English
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Endocrinology
    Abstract: Acute Pancreatitis (AP) in approximately 80% of cases, occurs as a secondary complication related to gallstone disease and alcohol misuse. However there are several other different causes that produce it such as metabolism, genetics, autoimmunity, post-ERCP, and trauma for example... This disease is commonly associated with the sudden onset of upper abdominal pain that is usually severe enough to warrant the patient seeking urgent medical attention. Overall, 10-25% of AP episodes are classified as severe. This leads to an associated mortality rate of 7-30% that has not changed in recent years. Treatment is conservative and generally performed by experienced teams often in ICUs. Although most cases of acute pancreatitis are uncomplicated and resolve spontaneously, the presence of complications has a significant prognostic importance. Necrosis, hemorrhage, and infection convey up to 25%, 50%, and 80% mortality, respectively. Other complications such as pseudocyst formation, pseudo-aneurysm formation, or venous thrombosis, increase morbidity and mortality to a lesser degree. The presence of pancreatic infection must be avoided
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  • 43
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    Hyperparathyroidism (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535104780 , 9789535169543
    Language: English
    Pages: 1 Online-Ressource (106 p.)
    Keywords: Endocrinology
    Abstract: This book is the result of the collaboration between worldwide authorities of different specialities in hyperparathyroidism. It aims to provide a general but deep view of primary/secondary and tertiary hyperparathyroidism, from a physiological basis to hyperparathyroidism in hemodialyzed patients, as well as new treatment approaches, techniques and surgical scenarios. We hope that the medical and paramedical researchers will find this book helpful and stimulating. We look forward to sharing knowledge of hyperparathyroidism with a wider audience
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  • 44
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    Hypothyroidism : Influences and Treatments (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100218 , 9789535168027
    Language: English
    Pages: 1 Online-Ressource (360 p.)
    Keywords: Endocrinology
    Abstract: Hypothyroidism is the most common thyroid disorder and it is significantly more frequent than presented - millions of people suffer from this disease without knowing it. People with this condition will have symptoms associated with slow metabolism. Estimates of subclinical hypothyroidism range between 3 to 8 %, increasing with age, whereas it more likely affects women than men. About 10% of women may have some degree of thyroid hormone deficiency. Hypothyroidism may affect lipid metabolism, neurological diseases or other clinical conditions. The book includes studies on advancements in diagnosis, regulation and replacement therapy, thyroid ultrasonography and radioiodine therapy for hypothyroidism. "Hypothyroidism - Influences and Treatments" contains many important specifications, results of scientific studies and innovations for endocrine practice
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  • 45
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    Thyroid Hormone (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535106784 , 9789535170181
    Language: English
    Pages: 1 Online-Ressource (398 p.)
    Keywords: Endocrinology
    Abstract: Thyroid hormone is important for controlling metabolism and many other body functions. Changes in thyroid hormone physiology, its regulation and diseases thereof have been a concern for the mankind. Understanding of the thyroid hormone(s) has been continuously updated and revised. The contributions from different authors have been incorporated in this book for this purpose. The original work of these contributors will be especially useful in furthering the knowledge on thyroid and help in creating new vistas of research
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  • 46
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    Pathophysiology and Complications of Diabetes Mellitus (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535108337 , 9789535170402
    Language: English
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Endocrinology
    Abstract: Diabetes mellitus is a complex, progressive disease, which is accompanied by multiple complications. It is a metabolic disorder of the endocrine system and listed among the most common disorders in both developed and developing countries. It has a global metabolic epidemic and it is estimated that the number of people affected by the disease will rise from the current 150 to 230 million by 2025. Hyperglycaemia is a characteristic feature of diabetes mellitus and chronic hyperglycaemia could lead to long-term complications in the eyes, kidneys, nerves, heart and blood vessels. Interestingly, this book examines the pathophysiology and selected complications in diabetes mellitus
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  • 47
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    Celiac Disease : From Pathophysiology to Advanced Therapies (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535106845 , 9789535170143
    Language: English
    Pages: 1 Online-Ressource (198 p.)
    Keywords: Endocrinology
    Abstract: Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye and barley) in genetically susceptible individuals. CD can manifest itself with a previously unappreciated range of clinical presentations, including the typical malabsorption syndrome and a spectrum of symptoms potentially affecting any organ system. Since CD often presents in an atypical or even silent manner, many cases remain undiagnosed and carry the risk of long-term complications, including anemia and other hematological complications, osteoporosis, neurological complications or cancer. The high prevalence of the disease and its variety of clinical outcomes raise several interesting questions. This book covers most of the aforementioned controversial and yet unresolved topics by including the contributions of experts in CD.What the reader will surely find stimulating about this book is not only its exhaustive coverage of our current knowledge of CD, but also provocative new concepts in disease pathogenesis and treatment
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  • 48
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    Cardiac Arrhythmias : New Considerations (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535101260 , 9789535168379
    Language: English
    Pages: 1 Online-Ressource (546 p.)
    Keywords: Cardiovascular medicine
    Abstract: The most intimate mechanisms of cardiac arrhythmias are still quite unknown to scientists. Genetic studies on ionic alterations, the electrocardiographic features of cardiac rhythm and an arsenal of diagnostic tests have done more in the last five years than in all the history of cardiology. Similarly, therapy to prevent or cure such diseases is growing rapidly day by day. In this book the reader will be able to see with brighter light some of these intimate mechanisms of production, as well as cutting-edge therapies to date. Genetic studies, electrophysiological and electrocardiographyc features, ion channel alterations, heart diseases still unknown , and even the relationship between the psychic sphere and the heart have been exposed in this book. It deserves to be read!
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  • 49
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    Congenital Heart Disease : Selected Aspects (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533074726 , 9789535166313
    Language: English
    Pages: 1 Online-Ressource (366 p.)
    Keywords: Cardiovascular medicine
    Abstract: There are significant advances in the understanding of the molecular mechanisms of cardiac development and the etiology of congenital heart disease (CHD). However, these have not yet evolved to such a degree so as to be useful in preventing CHD at this time. Developments such as early detection of the neonates with serious heart disease and their rapid transport to tertiary care centers, availability of highly sensitive noninvasive diagnostic tools, advances in neonatal care and anesthesia, progress in transcatheter interventional procedures and extension of complicated surgical procedures to the neonate and infant have advanced to such a degree that almost all congenital cardiac defects can be diagnosed and "corrected". Treatment of the majority of acyanotic and simpler cyanotic heart defects with currently available transcatheter and surgical techniques is feasible, effective and safe. The application of staged total cavo-pulmonary connection (Fontan) has markedly improved the long-term outlook of children who have one functioning ventricle. This book, I hope, will serve as a rich source of information to the physician caring for infants, children and adults with CHD which may help them provide optimal care for their patients
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  • 50
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    Deep Vein Thrombosis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102250 , 9789535168713
    Language: English
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book provides a comprehensive review of deep vein thrombosis. There are chapters on risk factors for DVT, post thrombotic syndrome and its management, vena cava malformation as a new etiological factor and thrombosis in the upper limbs. DVT is usually seen in patients undergoing major surgeries. The guidelines for thrombo-prophylaxis in orthopaedic patients, radical pelvic surgeries, laparoscopic operations and risks versus benefits in regions with a low prevalence of DVT are thoroughly addressed. Cancer and its treatment are recognized risk factors for VTE and extended prophylaxis in ambulatory cancer patients is reviewed. The role of imaging and endovascular therapies in acute DVT, hypercoagulabilty in liver diseases and the challenges in developing countries are discussed
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  • 51
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    State of the Art of Therapeutic Endocrinology (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535107729 , 9789535170310
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Endocrinology
    Abstract: During the last two decades, evidence of increasing trends of several endocrine-related disorders has been strengthened. These disorders often come with lack of uniform diagnosis and/ or even unclear endocrine disruption. The later is mainly due to abnormal classical changes in the blood- released hormone to its targeted organ, abnormal communication between cells within a tissue or organ (paracrine), within the same cell (intracrine) or signals which act on the same cell (autocrine). This challenging status drives endocrinologists to the urgent need to address enormous knowledge gaps in this wide field of research (Endocrinology). From the perspective point of view that "hormones control our bodies", we need to get these hormones rebalanced so we can restore overall health. That is simply endocrinology!
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  • 52
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    Atherogenesis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079929 , 9789535167846
    Language: English
    Pages: 1 Online-Ressource (584 p.)
    Keywords: Cardiovascular medicine
    Abstract: This monograph will bring out the state-of-the-art advances in the dynamics of cholesterol transport and will address several important issues that pertain to oxidative stress and inflammation. The book is divided into three major sections. The book will offer insights into the roles of specific cytokines, inflammation, and oxidative stress in atherosclerosis and is intended for new researchers who are curious about atherosclerosis as well as for established senior researchers and clinicians who would be interested in novel findings that may link various aspects of the disease
    Note: English
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  • 53
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    Inflammatory Bowel Disease (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535108795 , 9789535170471
    Language: English
    Pages: 1 Online-Ressource (292 p.)
    Keywords: Endocrinology
    Abstract: This book is an overview of invited contributions on recent data of inflammatory bowel diseases. The first part of the book covers topics related to the ethiopathogenesis of inflammatory bowel diseases including the environmental, genetic factors and immunological alternations. The next chapters deal with present day management of disease including radiological diagnosis and surgical treatment, which consider the advances of most up-to-date radiological methodology including MRI techniques and the role of surgical procedures in the therapy. The final part presents medical therapy and its future directions. These chapters discuss natural products exerting anti-inflammatory and anti-tumour effects, methods of colon targeting drug delivery systems including polysaccharides, peptides and nanoparticules; as well as the potential risks of nanotechnology based food materials
    Note: English
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  • 54
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    Portal Hypertension : Causes and Complications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102519 , 9789535168843
    Language: English
    Pages: 1 Online-Ressource (158 p.)
    Keywords: Endocrinology
    Abstract: Portal hypertension is a clinical syndrome defined by a portal venous pressure gradient, exceeding 5 mm Hg. In this book the causes of its development and complications are described. Authors have presented personal experiences on conducting patients with various displays of portal hypertension. Moreover, the book presents modern data about molecular mechanisms of pathogenesis of portal hypertension in liver cirrhosis, the information about the original predictor of risk of bleeding from gastro-esophageal varices and new methods for their conservative treatment
    Note: English
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  • 55
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    A New Look at Hypothyroidism (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100201 , 9789535168010
    Language: English
    Pages: 1 Online-Ressource (268 p.)
    Keywords: Endocrinology
    Abstract: Hypothyroidism is the most common thyroid disorder. It can cause a variety of changes in women's menstrual periods, reduce their chances of becoming pregnant, as well as affect both the course of pregnancy and the neuropsychological development of babies. During pregnancy there is a substantially increased need for thyroid hormones and a substantial risk that a previously unnoticed, subclinical or latent hypothyroidism will turn into overt hypothyroidism. The thyroid inflammation caused by the patient's own immune system may form autoimmune thyroiditis (Hashimoto's thyroiditis). Congenital hypothyroidism (CH) occurs in approximately 1:2,000 to 1:4,000 newborns. Nearly all of the developed world countries currently practice newborn screening to detect and treat congenital hypothyroidism in the first weeks of life. "A New Look at Hypothyroidism" contains many important specifications and innovations for endocrine practice
    Note: English
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  • 56
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    Endocarditis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen | Rijeka : IntechOpen
    Details
    ISBN: 9789535167563
    Language: English
    Pages: 1 Online-Ressource (152 Seiten) , Illustrationen (teilweise farbig), Tabellen
    Edition: First published
    Keywords: Endocrinology
    Abstract: Endocarditis is a disease that occurs as a result of the inflammation of the endocardium. It is an inflammatory process located in the inner lining of the cardiac chambers and native or prosthetic valves. It is characterized by colonization or invasion of the heart valve vegetations composed of platelets forming, fibrin and microcolonies of microorganisms, and occasionally of inflammatory cells. Other structures may also be affected, such as the interventricular septum, chordae tendineae, the mural endocardium or even intra-cardiac implants. The book covers, with scientific rigour, the most prevalent causes and current treatments of endocarditis, as well as the cases when the organs remote from the heart are affected by this disease
    Note: Literaturangaben
    DOI: 10.5772/1192
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  • 57
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    The Cardiovascular System : Physiology, Diagnostics and Clinical Implications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105343 , 9789535169741
    Language: English
    Pages: 1 Online-Ressource (494 p.)
    Keywords: Cardiovascular medicine
    Abstract: The cardiovascular system includes the heart located centrally in the thorax and the vessels of the body which carry blood. The cardiovascular (or circulatory) system supplies oxygen from inspired air, via the lungs to the tissues around the body. It is also responsible for the removal of the waste product, carbon dioxide via air expired from the lungs. The cardiovascular system also transports nutrients such as electrolytes, amino acids, enzymes, hormones which are integral to cellular respiration, metabolism and immunity. This book is not meant to be an all encompassing text on cardiovascular physiology and pathology rather a selection of chapters from experts in the field who describe recent advances in basic and clinical sciences. As such, the text is divided into three main sections: Cardiovascular Physiology, Cardiovascular Diagnostics and lastly, Clinical Impact of Cardiovascular Physiology and Pathophysiology
    Note: English
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  • 58
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    Coronary Artery Disease : Current Concepts in Epidemiology, Pathophysiology, Diagnostics and Treatment (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102625 , 9789535168904
    Language: English
    Pages: 1 Online-Ressource (288 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiovascular disease is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. Heart disease kills one person every 34 seconds in the USA alone. Although the leading killer, the incidence of cardiovascular disease has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy new drug regimens including low molecular weight heparin and antiplatelet drugs such as glycoprotein IIb/IIIa receptor inhibitors and acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text aims to deliver the current understanding of coronary artery disease and is split into three main sections: 1. Epidemiology and pathophysiology of coronary artery disease 2. Coronary artery disease diagnostics and 3. Treatment regimens for coronary artery disease
    Note: English
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  • 59
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    Acute Coronary Syndromes (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078274 , 9789535167075
    Language: English
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book has been written with the intention of providing an up-to-the minute review of acute coronary syndromes. Atherosclerotic coronary disease is still a leading cause of death within developed countries and not surprisingly, is significantly rising in others. Over the past decade the treatment of these syndromes has changed dramatically. The introduction of novel therapies has impacted the outcomes and surviving rates in such a way that the medical community need to be up to date almost on a "daily bases". It is hoped that this book will provide a timely update on acute coronary syndromes and prove to be an invaluable resource for practitioners seeking new and innovative ways to deliver the best possible care to their patients
    Note: English
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  • 60
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    Aneurysm (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535107309 , 9789535170259
    Language: English
    Pages: 1 Online-Ressource (488 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book's focus is on diagnosis and treatment of intracranial aneurysm, abdominal and thoracic aortic aneurysms. It addresses neurosurgical, vascular and cardiothoracic surgeons and interventional radiologists, but also anyone engaged in vascular medicine. It presents is an effort to collect an up-to-date account of existing knowledge, involving recent developments in this field. Various experts described details of established knowledge or newly recognized advances associated with diagnosis, treatment, perioperative management and mechanism. This is the first book that deals with the whole body aneurysm, such as cerebral aneurysm, abdominal aneurysm, and splenial aneurysm and to learn the latest developments in other fields is always useful. I hope this book will be used worldwide by vascular surgeons and interventionalists enhancing their knowledge and stimulating the advancement of this field
    Note: English
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  • 61
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    Cardiomyopathies : From Basic Research to Clinical Management (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078342 , 9789535167099
    Language: English
    Pages: 1 Online-Ressource (816 p.)
    Keywords: Cardiovascular medicine
    Abstract: Cardiomyopathy means "heart (cardio) muscle (myo) disease (pathy)". Currently, cardiomyopathies are defined as myocardial disorders in which the heart muscle is structurally and/or functionally abnormal in the absence of a coronary artery disease, hypertension, valvular heart disease or congenital heart disease sufficient to cause the observed myocardial abnormalities. This book provides a comprehensive, state-of-the-art review of the current knowledge of cardiomyopathies. Instead of following the classic interdisciplinary division, the entire cardiovascular system is presented as a functional unity, and the contributors explore pathophysiological mechanisms from different perspectives, including genetics, molecular biology, electrophysiology, invasive and non-invasive cardiology, imaging methods and surgery. In order to provide a balanced medical view, this book was edited by a clinical cardiologist
    Note: English
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  • 62
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    Glucose Tolerance (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535108917 , 9789535170518
    Language: English
    Pages: 1 Online-Ressource (256 p.)
    Keywords: Endocrinology
    Abstract: The progression from normal glucose tolerance (NGT) to type 2 diabetes involves intermediate stages of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), also known as prediabetes. The pathophysiology underlying the development of these glucose metabolic alterations is multifactorial, leading to an alteration in the balance between insulin sensitivity and insulin secretion. Our knowledge of the molecular basis of the signaling pathways mediating the various physiologic effects of insulin is steadily advancing. New substrates and signaling molecules have been identified and potential mechanisms involved in the pathophysiology of type 2 diabetes have been revealed. This book summarises the current state of knowledge on the pathophysiology underlying the progression from normal glucose tolerance to type 2 diabetes and therapeutic advances in the improvement of glycaemic control in prediabetic and diabetic states
    Note: English
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  • 63
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    Thyroid and Parathyroid Diseases : New Insights into Some Old and Some New Issues (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102212 , 9789535168690
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Endocrinology
    Abstract: This book was designed to meet the requirements of all who wish to acquire profound knowledge of basic, clinical, psychiatric and laboratory concepts as well as surgical techniques regarding thyroid and parathyroid glands. It was divided into three main sections: 1. Evaluating the Thyroid Gland and its Diseases includes basic and clinical information on the most novel and quivering issues in the area. 2. Psychiatric Disturbances Associated to Thyroid Diseases addresses common psychiatric disturbances commonly encountered in the clinical practice. 3. Treatment of Thyroid and Parathyroid Diseases discusses the management of thyroid and parathyroid diseases including new technologies
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    Coronary Artery Diseases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102380 , 9789535168805
    Language: English
    Pages: 1 Online-Ressource (346 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book has "wide geography" both literally and figuratively. First of all, this book brings together contributions from around the world, both from post-industrial countries and developing world. This is natural, because coronary artery disease is becoming pandemic worldwide. CAD is the single most frequent cause of death in developed countries, causes about 1 in every 5 deaths. Mortality from cardiovascular disease is predicted to reach 23.4 million in 2030. Moreover, in the developing world, cardiovascular disease tends to affect people at a younger age and thus could negatively affect the workforce and economic productivity. The morbidity, mortality, and socioeconomic importance of CAD make its diagnosis and management fundamental for all practicing physicians. On another hand, the book widely represents "geography" of CAD itself, i.e. many various aspects of its pathophysiology, epidemiology, diagnosis, treatment are touched in this book. This book does not pretend on complete and integral description of the Coronary artery disease. Rather, it contains selected issues on this complex multifactorial disease. Nevertheless, we hope that readers will find Coronary Artery Disease useful for clinical practice and further research
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  • 65
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    Hydrocephalus (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535101628 , 9789535152125
    Language: English
    Pages: 1 Online-Ressource (228 p.)
    Keywords: Endocrinology
    Abstract: Description of hydrocephalus can be found in ancient medical literature from Egypt as old as 500 AD. Hydrocephalus is characterized by abnormal accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. This results in the rise of intracranial pressure inside the skull causing progressive increase in the size of the head, seizure, tunneling of vision, and mental disability. The clinical presentation of hydrocephalus varies with age of onset and chronicity of the underlying disease process. Acute dilatation of the ventricular system manifests with features of raised intracranial pressure while chronic dilatation has a more insidious onset presenting as Adams triad. Treatment is generally surgical by creating various types of cerebral shunts. Role of endoscopic has emerged lately in the management of hydrocephalus
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    Atrial Septal Defect (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105312 , 9789535169710
    Language: English
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Endocrinology
    Abstract: Atrial Septal Defects (ASDs) are relatively common both in children and adults. Recent reports of increase in the prevalence of ASD may be related use of color Doppler echocardiography. The etiology of the ASD is largely unknown. While the majority of the book addresses closure of ASDs, one chapter in particular focuses on creating atrial defects in the fetus with hypoplastic left heart syndrome. This book, I hope, will give the needed knowledge to the physician caring for infants, children, adults and elderly with ASD which may help them provide best possible care for their patients
    Note: English
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    Inflammatory Bowel Disease : Advances in Pathogenesis and Management (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078915 , 9789535167532
    Language: English
    Pages: 1 Online-Ressource (346 p.)
    Keywords: Endocrinology
    Abstract: This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature
    Note: English
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    Appendicitis : A Collection of Essays from Around the World (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078144 , 9789535166283
    Language: English
    Pages: 1 Online-Ressource (238 p.)
    Keywords: Endocrinology
    Abstract: This book is a collection of essays and papers from around the world, written by surgeons who look after patients of all ages with abdominal pain, many of whom have appendicitis. All general surgeons maintain a fascination with this important condition because it is so common and yet so easy to miss. All surgeons have a view on the literature and any gathering of surgeons embraces a spectrum of opinion on management options. Many aspects of the disease and its presentation and management remain controversial. This book does not answer those controversies, but should prove food for thought. The reflections of these surgeons are presented in many cases with novel data. The chapters encourage us to consider new epidemiological views and explore clinical scoring systems and the literature on imaging. Appendicitis is discussed in patients of all ages and in all manner of presentations
    Note: English
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    Pancreatitis : Treatment and Complications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535101093 , 9789535168317
    Language: English
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Endocrinology
    Abstract: Pancreatitis may be acute or chronic. Although they can be caused by similar aetiologies, they tend to follow distinct natural histories. Around 80% of acute pancreatitis (AP) diagnoses occur as secondary to gallstone disease and alcohol misuse. This disease is commonly associated with the sudden onset of upper abdominal that is usually severe enough to warrant the patient seeking urgent medical attention. Overall, 10 to 25% of AP episodes are classified as severe, leading to an associated mortality rate of 7 to 30%. Treatment is conservative and consists of general medical support performed by experienced teams, sometimes in ICUs. Although most cases of acute pancreatitis are uncomplicated and resolve spontaneously, the presence of complications has significant prognostic importance. Necrosis, hemorrhage, and infection convey rates of up to 25%, 50%, and 80% mortality, respectively. Other complications such as pseudocyst formation, pseudoaneurysm formation, or venous thrombosis increase morbidity and mortality to a lesser degree. The presence of pancreatic infection must be avoided
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    Venous Thrombosis : Principles and Practice (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078854 , 9789535167495
    Language: English
    Pages: 1 Online-Ressource (244 p.)
    Keywords: Cardiovascular medicine
    Abstract: According to Virchow's triad, venous thrombosis can occur as a result of one or more of three factors: changes in the dynamics of the blood flow, endothelial injury/dysfunction of the blood vessel and hypercoagulability. The blood in the veins is constantly forming microscopic thrombi that are routinely broken down by the body, and significant clotting can occur only when the balance of thrombus formation and resolution is altered. This book is a fresh synthesis of venous thromboembolism care and considers the opinions and studies from different fields of medicine. As venous thrombosis spectrum is wide and can affect many organ systems, from deep veins of the leg to the cerebral venous system, our intent is for this to be a comprehensive, up-to-date and readable book. We tried to present a synthesis of existing material infused with new ideas and perspectives and authors own clinical studies and even case-reports
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    Osteosarcoma (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105060 , 9789535169642
    Language: English
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Cardiovascular medicine
    Abstract: This book is aimed at quickly updating the reader on osteosarcoma, a dreaded primary bone cancer. Progress in management of osteosarcoma has been slow after the evolution of chemotherapy and limb salvage surgery. Research is now directed towards identifying molecular targets for systemic therapy. Availability of chemotherapy drugs and low cost implants in developing world have allowed limb salvage surgery to develop. This book looks at current basic knowledge on osteosarcoma and some of the developments in research which have the potential to change the prognosis
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    Advances in Electrocardiograms : Methods and Analysis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079233 , 9789535167624
    Language: English
    Pages: 1 Online-Ressource (404 p.)
    Keywords: Cardiovascular medicine
    Abstract: Electrocardiograms are one of the most widely used methods for evaluating the structure-function relationships of the heart in health and disease. This book is the first of two volumes which reviews recent advancements in electrocardiography. This volume lays the groundwork for understanding the technical aspects of these advancements. The five sections of this volume, Cardiac Anatomy, ECG Technique, ECG Features, Heart Rate Variability and ECG Data Management, provide comprehensive reviews of advancements in the technical and analytical methods for interpreting and evaluating electrocardiograms. This volume is complemented with anatomical diagrams, electrocardiogram recordings, flow diagrams and algorithms which demonstrate the most modern principles of electrocardiography. The chapters which form this volume describe how the technical impediments inherent to instrument-patient interfacing, recording and interpreting variations in electrocardiogram time intervals and morphologies, as well as electrocardiogram data sharing have been effectively overcome. The advent of novel detection, filtering and testing devices are described. Foremost, among these devices are innovative algorithms for automating the evaluation of electrocardiograms
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    Cardiotoxicity of Oncologic Treatments (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102731 , 9789535168935
    Language: English
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Cardiovascular medicine
    Abstract: The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer
    Note: English
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    Novel Strategies in Ischemic Heart Disease (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535101840 , 9789535168621
    Language: English
    Pages: 1 Online-Ressource (464 p.)
    Keywords: Cardiovascular medicine
    Abstract: The first edition of this book will provide a comprehensive overview of ischemic heart disease, including epidemiology, risk factors, pathogenesis, clinical presentation, diagnostic tests, differential diagnosis, treatment, complications and prognosis. Also discussed are current treatment options, protocols and diagnostic procedures, as well as the latest advances in the field. The book will serve as a cutting-edge point of reference for the basic or clinical researcher, and any clinician involved in the diagnosis and management of ischemic heart disease. This book is essentially designed to fill the vital gap existing between these practices, to provide a textbook that is substantial and readable, compact and reasonably comprehensive, and to provide an excellent blend of "basics to bedside and beyond" in the field of ischemic heart disease. The book also covers the future novel treatment strategies, focusing on the basic scientific and clinical aspects of the diagnosis and management of ischemic heart disease
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    Insulin Resistance (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535108900 , 9789535170501
    Language: English
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Endocrinology
    Abstract: This book has been made possible by the contributions of leading scientists and clinicians from upcoming and interdisciplinary fields of research concerning the molecular and clinical features of insulin resistance. Multiple metabolic disturbances associated with Insulin Resistance include inflammatory cytokines, adipokines, endothelial dysfunction, tissue-specific defects in insulin action and signaling, oxidative stress, ectopic lipid deposition, and disordered neuroregulation. This book aims to encourage scientists and physicians - working separately on various aspects of Insulin resistance and metabolic syndrome for early detection of the first signs indicating the onset of a metabolic misbalance in order to prevent the consecutive cascades which lead to metabolic syndrome, resulting in the so-called diseases of modern civilization - cancer, diabetes and hypertension
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    Constipation : Causes, Diagnosis and Treatment (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102373 , 9789535168799
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Constipation is common in both adults and children. Estimates would suggest a median prevalence of around 12-16% in the general population. While regarded as a minor nuisance in some cases, its consequences can be severe, with a substantial impact on quality of life. Secondary faecal soiling has a profound psychological effect at all ages. This book provides contributions from authors with a range of backgrounds which clarify the pathogenesis, diagnosis, and therapy of constipation for the general population and also for certain high risk groups
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    Dyslipidemia : From Prevention to Treatment (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079042 , 9789535167594
    Language: English
    Pages: 1 Online-Ressource (482 p.)
    Keywords: Endocrinology
    Abstract: Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment
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    Ulcerative Colitis : from Genetics to Complications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078533 , 9789535167235
    Language: English
    Pages: 1 Online-Ressource (236 p.)
    Keywords: Endocrinology
    Abstract: Ulcerative Colitis (UC) is a rapidly evolving medical field, and will continue to be very exiting in the next few decades. Although the underlying cause of this disease is still unknown, results in research dealing with various issues related to this disease are published every day. Chapters included in this book review the most recent literature on related advancements in regard to this chronic disease, which is controllable but not curable. Aspects like epidemiology, pathophysiology, genetics, incriminated etiologies, clinical aspects, complications, and disease management, including advancements in the diagnostic and therapeutic options, were documented by well known clinicians, researchers, and world wide authorities in their fields. This book on UC will be a valuable addition to each doctor's library interested in this subject, or for physicians dealing with patients suffering from this disease. Authors have also included figures and diagrams to depict their point, and to easily reach the minds of the readers in the simplest way
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  • 79
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    Neuroendocrinology and Behavior (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535107408 , 9789535153184
    Language: English
    Pages: 1 Online-Ressource (178 p.)
    Keywords: Endocrinology
    Abstract: Understanding of the neuroendocrine system provides an insight into a wide range of bodily and mental processes. Neuroendocrinology and Behavior brings its readers a concise guide to up-to-date knowledge on the function of the endocrine glands and organs in association with neurotransmitters, neuropeptides, and behavioral manifestations. Various forms of stress response, e.g. anxiety and cognitive changes, have been intrinsic to both ourselves and other species. Specifically, these mechanisms involve complex interplays among physical, emotional, and behavioral processes in humans. This volume provides information on peptide hormones, i.e. oxytocin and vasopressin, and how studies of these neuropeptides enrich our understanding of social and other behaviors. These neuromodulators also affect sexual behavior and water balance in the body, an issue also addressed in this Book
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  • 80
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    Gastroesophageal Reflux Disease (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535103141 , 9789535169079
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Endocrinology
    Abstract: Gastroesophageal reflux disease affects many patients. This disease not only lowers their quality of life, but it also threatens some of them with an underhand risk of cancer. Additionally, it becomes an economic burden for the patients and society. The aim of this book on gastroesophageal reflux disease is to provide advice and guidance to gastroenterologists to help them understand and manage some aspects of this proteiform disease
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  • 81
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    Coronary Artery Disease : New Insights and Novel Approaches (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535103448 , 9789535169192
    Language: English
    Pages: 1 Online-Ressource (272 p.)
    Keywords: Cardiovascular medicine
    Abstract: Coronary Artery disease is one of the leading causes of death in industrialized countries and is responsible for one out of every six deaths in the United States. Remarkably, coronary artery disease is also largely preventable. The biggest challenge in the next years is to reduce the incidence of coronary artery disease worldwide. A complete knowledge of the mechanisms responsible for the development of ischaemic heart disease is an essential prerequisite to a better management of this pathology improving prevention and therapy. This book has been written with the intention of providing new concepts about coronary artery disease pathogenesis that may link various aspects of the disease, going beyond the traditional risk factors
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  • 82
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    Chronic Pancreatitis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100119 , 9789535167976
    Language: English
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Endocrinology
    Abstract: Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted
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  • 83
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    Cardiac Transplantation (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100003 , 9789535167891
    Language: English
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Endocrinology
    Abstract: We are truly in an era of change not only in terms of technology but in the type of patient we are caring for. That is why I feel this book is exciting in that it presents the team approach to the transplant patient. I am confident that the pioneers of cardiac transplantation would be pleased with our response to challenges in healthcare today and be pleased with the final product
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  • 84
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    Crohn's Disease (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078113 , 9789535166306
    Language: English
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Endocrinology
    Abstract: In this book, several important points regarding Crohn's disease are discussed. In the first section, we focus on etiopathogeny of Crohn's disease and the recent advances in our overall understanding of the disease - specifically, the role of the gut epithelium, alterations of the epithelial crypts, and the roles of the different cytokines in the pathophysiology of Crohn's disease. In the second section, a diagnosis of Crohn's disease is discussed. Another particular area of focus is in the diagnosis of intestinal tuberculosis, and the role of mycobacterium avium in Crohn's disease. In the third and final section, the management of Crohn's disease is discussed, with a focus on recent evidence-based medicine recommendations
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  • 85
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    Recent Advances in Cardiovascular Risk Factors (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103219 , 9789535169109
    Language: English
    Pages: 1 Online-Ressource (526 p.)
    Keywords: Cardiovascular medicine
    Abstract: Among the non-communicable diseases, cardiovascular disorders are the leading cause of morbidity and mortality in both the developed and the developing countries. The spectrum of risk factors is wide and their understanding is imperative to prevent the first and recurrent episodes of myocardial infarction, stroke or peripheral vascular disease which may prove fatal or disabling. This book has tried to present an update on risk factors incorporating new research which has thrown more light on the existing knowledge. It has also tried to highlight regional diversity addressing such issues. It will hopefully be resourceful to the cardiologists, general practitioners, family physicians, researchers, graduate students committed to cardiovascular risk prevention
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  • 86
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    Cholestasis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535100430 , 9789535168164
    Language: English
    Pages: 1 Online-Ressource (108 p.)
    Keywords: Endocrinology
    Abstract: This book covers different aspects on the understanding of mechanisms, effects, and management of cholestasis. This unique compendium contains important citations, an invaluable amount of research work, and many applications, which are outstanding resources for clinicians, pharmacists, biochemists, upper-level undergraduate, graduate, and continuing-education students who are dedicated to discovering new knowledge on cholestasis
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  • 87
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    Pituitary Adenomas (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100416 , 9789535168157
    Language: English
    Pages: 1 Online-Ressource (98 p.)
    Keywords: Endocrinology
    Abstract: Pituitary Adenomas is a comprehensive book about the most common pathology of the pituitary gland in the sellar region. The book chapters include epidemiology, symptoms and signs, clinical, imaging, immunohistochemical and ultrastructural pathological diagnosis, therapeutic approaches and outcome of the functional and non-functional pituitary tumors. Therapies include medications, endoscopic transphenoidal and open surgeries; radiotherapy includes gamma knife radiosurgery. Visual symptoms has important and characteristic patterns which has discussed in one specific chapter. Endocrine secretion is another characteristic in 40% of pituitary adenomas. Therefore, another chapter presents it. Stereotactic radiosurgery and endoscopic surgery both have special role in recent decades. Thus, they have considered specifically, too. Authors expect to give excellent insight in pituitary adenoma to the book readers
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  • 88
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    Chronic Lymphocytic Leukemia (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078816 , 9789535167464
    Language: English
    Pages: 1 Online-Ressource (464 p.)
    Keywords: Cardiovascular medicine
    Abstract: B-cell chronic lymphocytic leukemia (CLL) is considered a single disease with extremely variable course, and survival rates ranging from months to decades. It is clear that clinical heterogeneity reflects biologic diversity with at least two major subtypes in terms of cellular proliferation, clinical aggressiveness and prognosis. As CLL progresses, abnormal hematopoiesis results in pancitopenia and decreased immunoglobulin production, followed by nonspecific symptoms such as fatigue or malaise. A cure is usually not possible, and delayed treatment (until symptoms develop) is aimed at lengthening life and decreasing symptoms. Researchers are playing a lead role in investigating CLL's cause and the role of genetics in the pathogenesis of this disorder. Research programs are dedicated towards understanding the basic mechanisms underlying CLL with the hope of improving treatment options
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  • 89
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    Microangiopathy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104193 , 9789535169383
    Language: English
    Pages: 1 Online-Ressource (94 p.)
    Keywords: Endocrinology
    Abstract: Microangiopathies are pathological processes causing degenerative disorders of small vessels. The circulatory problems caused by microangiopathies may be responsible for failure of individual or multiple organs. These pathological processes are indeed one of the most common disorders characterized by high morbility and mortality in the affected patients. Many studies have revealed very complicated processes both at cellular and molecular level. However, much work remains to define the diversity of different pathogenetic mechanisms leading to microangiopathic disorders to provide appropriate prevention and treatment strategies. The aim of this volume is providing illustrative examples of relevant mechanisms responsible for different forms of microangiopathies and how this body of evidences can be harnessed to define new strategies of therapeutic intervention
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  • 90
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    Advances in Electrocardiograms : Clinical Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533079028 , 9789535167570
    Language: English
    Pages: 1 Online-Ressource (342 p.)
    Keywords: Cardiovascular medicine
    Abstract: Electrocardiograms have become one of the most important, and widely used medical tools for diagnosing diseases such as cardiac arrhythmias, conduction disorders, electrolyte imbalances, hypertension, coronary artery disease and myocardial infarction. This book reviews recent advancements in electrocardiography. The four sections of this volume, Cardiac Arrhythmias, Myocardial Infarction, Autonomic Dysregulation and Cardiotoxicology, provide comprehensive reviews of advancements in the clinical applications of electrocardiograms. This book is replete with diagrams, recordings, flow diagrams and algorithms which demonstrate the possible future direction for applying electrocardiography to evaluating the development and progression of cardiac diseases. The chapters in this book describe a number of unique features of electrocardiograms in adult and pediatric patient populations with predilections for cardiac arrhythmias and other electrical abnormalities associated with hypertension, coronary artery disease, myocardial infarction, sleep apnea syndromes, pericarditides, cardiomyopathies and cardiotoxicities, as well as innovative interpretations of electrocardiograms during exercise testing and electrical pacing
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  • 91
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    Atrial Fibrillation : Basic Research and Clinical Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533073996 , 9789535166252
    Language: English
    Pages: 1 Online-Ressource (416 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atrial Fibrillation-Basic Research and Clinical Applications is designed to provide a comprehensive review and to introduce outstanding and novel researches. This book contains 22 polished chapters and consists of five sections: 1. Basic mechanisms of initiation and maintenance of atrial fibrillation and its pathophysiology, 2. Mapping of atrial fibrillation and novel methods of signal detection. 3. Clinical prognostic predictors of atrial fibrillation and remodeling, 4. Systemic reviews of catheter-based/surgical treatment and novel targets for treatment of atrial fibrillation and 5. Atrial fibrillation in specific conditions and its complications. Each chapter updates the knowledge of atrial fibrillation, providing state-of-the art for not only scientists and clinicians who are interested in electrophysiology, but also general cardiologists
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  • 92
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    Trends in Alcoholic Liver Disease Research : Clinical and Scientific Aspects (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533079851 , 9789535167808
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Endocrinology
    Abstract: Alcoholic liver disease occurs after prolonged heavy drinking. Not everyone who drinks alcohol in excess develops serious forms of alcoholic liver disease. It is likely that genetic factors determine this individual susceptibility, and a family history of chronic liver disease may indicate a higher risk. Other factors include being overweight and iron overload. This book presents state-of-the-art information summarizing the current understanding of a range of alcoholic liver diseases. It is hoped that the target readers - hepatologists, clinicians, researchers and academicians - will be afforded new ideas and exposed to subjects well beyond their own scientific disciplines. Additionally, students and those who wish to increase their knowledge will find this book a valuable source of information
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  • 93
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    Steroids : Basic Science (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078663 , 9789535167341
    Language: English
    Pages: 1 Online-Ressource (246 p.)
    Keywords: Endocrinology
    Abstract: This book explains the basic science of steroids and is targeted towards professionals engaged in health services. It should be noted that medical science evolves rapidly and some information like the understanding of steroids and their therapeutic use may change with new concepts quickly. Steroids are either naturally occurring or synthetic fat-soluble organic compounds. They are found in plants, animals, and fungi. They mediate a very diverse set of biological responses. The most widespread steroid in the body is cholesterol, an essential component of cell membranes, and the starting point for the synthesis of other steroids. Since the science of steroids has an enormous scope, we decided to put the clinical aspects of steroids in a different book titled "Steroids-Clinical Aspects". The two books complete each other. We hope that the reader will gain valuable information from both books and enrich their knowledge about this fascinating topic
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  • 94
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    Traditional and Novel Risk Factors in Atherothrombosis (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105619 , 9789535169826
    Language: English
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Cardiovascular medicine
    Abstract: Atherothrombosis has reached pandemic proportions worldwide. It is the underlying condition that results in events leading to myocardial infarction, ischemic stroke and vascular death. As such, it is the leading cause of death worldwide manifested mainly as cardiovascular/cerebrovascular death. The complex and intimate relationship between atherothrombosis and traditional and novel risk factors is discussed in the following chapters of Traditional and Novel Risk Factors in Atherothrombosis - from basic science to clinical and therapeutic concerns. Beginning with pathology and pathophysiology of atherothrombosis, plaque rupture/disruption, this book continues with molecular, biochemical, inflammatory, cellular aspects and finally analyzes several aspects of clinical pharmacology
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  • 95
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    Modern Pacemakers : Present and Future (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533072142 , 9789535164234
    Language: English
    Pages: 1 Online-Ressource (626 p.)
    Keywords: Cardiovascular medicine
    Abstract: The book focuses upon clinical as well as engineering aspects of modern cardiac pacemakers. Modern pacemaker functions, implant techniques, various complications related to implant and complications during follow-up are covered. The issue of interaction between magnetic resonance imaging and pacemakers are well discussed. Chapters are also included discussing the role of pacemakers in congenital and acquired conduction disease. Apart from pacing for bradycardia, the role of pacemakers in cardiac resynchronization therapy has been an important aspect of management of advanced heart failure. The book provides an excellent overview of implantation techniques as well as benefits and limitations of cardiac resynchronization therapy. Pacemaker follow-up with remote monitoring is getting more and more acceptance in clinical practice; therefore, chapters related to various aspects of remote monitoring are also incorporated in the book. The current aspect of cardiac pacemaker physiology and role of cardiac ion channels, as well as the present and future of biopacemakers are included to glimpse into the future management of conductions system diseases. We have also included chapters regarding gut pacemakers as well as pacemaker mechanisms of neural networks. Therefore, the book covers the entire spectrum of modern pacemaker therapy including implant techniques, device related complications, interactions, limitations, and benefits (including the role of pacing role in heart failure), as well as future prospects of cardiac pacing
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  • 96
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    Therapeutic Gastrointestinal Endoscopy (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533077437 , 9789535164944
    Language: English
    Pages: 1 Online-Ressource (230 p.)
    Keywords: Endocrinology
    Abstract: Endoscopy has had a big role in the development of modern gastroenterology. Modern endoscopy will certainly be more therapeutic. It started with endoscopic hemostasis and polipectomy, than beginning of the 1970's with the advent of endoscopic sphincterotomy extended to biliopancreatic pathology and has a huge impact in this difficult pathology. Plastic stents made the first steps in endoscopic palliation of neoplastic jaundice, metallic stents, covered or uncovered are better for biliary palliation and can be used also for palliation neoplastic obstruction at different levels of the digestive tube. Resection of digestive tumors has evolved now to sub-mucosal resection, looking to have one-piece complete resection. Interventional endoscopy is now very complex and takes a lot of time for endoscopists to learn properly these techniques. This book is a very good up-to-date overview of new techniques of interventional endoscopy for those who want to learn or develop their knowledges in this field
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  • 97
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    Ulcerative Colitis : Epidemiology, Pathogenesis and Complications (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078809 , 9789535167457
    Language: English
    Pages: 1 Online-Ressource (294 p.)
    Keywords: Endocrinology
    Abstract: This book is intended to act as an up-to-date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular, Ulcerative Colitis. All authors of the chapters are experts in their fields of publication, and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating, and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine
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  • 98
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    Cardiac Defibrillation : Prediction, Prevention and Management of Cardiovascular Arrhythmic Events (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533076928 , 9789535165675
    Language: English
    Pages: 1 Online-Ressource (190 p.)
    Keywords: Cardiovascular medicine
    Abstract: Millions of people throughout the world currently depend on appropriate, timely shocks from implantable cardioverter defibrillators (ICDs) to avoid sudden death due to cardiovascular malfunctions. Therefore, information regarding the use, applications, and clinical relevance of ICDs is imperative for expanding the body of knowledge used to prevent and manage fatal cardiovascular behavior. As such, the apt and timely research contained in this book will prove both relevant to current ICD usage and valuable in helping advance ICD technology. This book is divided into three comprehensive sections in order to cover several areas of ICD research. The first section introduces defibrillator technology, discusses determinants for successful defibrillation, and explores assessments of patients who receive defibrillation. The next section talks about predicting, preventing, and managing near catastrophic cardiovascular events, and research presented in the final section examine special cases in ICD patients and explore information that can be learned through clinical trial examinations of patients with defibrillators. Each chapter of this book will help answer critical questions about ICDs
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  • 99
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    Global Perspective on Diabetic Foot Ulcerations (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533077277 , 9789535166023
    Language: English
    Pages: 1 Online-Ressource (290 p.)
    Keywords: Endocrinology
    Abstract: Over the last decade, it is becoming increasingly clear that diabetes mellitus is a global epidemic. The influence of diabetes is most readily apparent in its manifestation in foot complications across cultures and continents. In this unique collaboration of global specialists, we examine the explosion of foot disease in locations that must quickly grapple with both mobilizing medical expertise and shaping public policy to best prevent and treat these serious complications. In other areas of the world where diabetic foot complications have unfortunately been all too common, diagnostic testing and advanced treatments have been developed in response. The bulk of this book is devoted to examining the newest developments in basic and clinical research on the diabetic foot. It is hoped that as our understanding of the pathophysiologic process expands, the devastating impact of diabetic foot complications can be minimized on a global scale
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  • 100
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    Hypoglycemia : Causes and Occurrences (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076577 , 9789535165200
    Language: English
    Pages: 1 Online-Ressource (252 p.)
    Keywords: Endocrinology
    Abstract: Glucose is an essential metabolic substrate of all mammalian cells being the major carbohydrate presented to the cell for energy production and also many other anabolic requirements. Hypoglycemia is a disorder where the glucose serum concentration is usually low. The organism usually keeps the glucose serum concentration in a range of 70 to 110 mL/dL of blood. In hypoglycemia the glucose concentration normally remains lower than 50 mL/dL of blood. This book provides an abundance of information for all who need them in order to help many people worldwide
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