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  • 1
    ISBN: 9789535134749 , 9789535134732 , 9789535146872
    Language: Undetermined
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Medical genetics
    Abstract: This edited book, Chromosomal Abnormalities - A Hallmark Manifestation of Genomic Instability, contains a series of chapters highlighting several aspects related to the generation of chromosomal abnormalities in genetic material. We are extremely grateful to the authors who had contributed with valuable information about the role of genomic instability in pathological disorders as well as in the evolution process
    Note: English
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  • 2
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535129509 , 9789535129493 , 9789535154709
    Language: Undetermined
    Pages: 1 Online-Ressource (134 p.)
    Keywords: Medical genetics
    Abstract: Genetic diversity is the entire amount of genes and genotypes in a group of organisms and is of vital importance for their adaptation to different living conditions. If, for example, all humans were identical, the extinction of the entire kind could happen very fast. Let us care and nourish differences! The goal of this book is to present some of the contemporary thoughts on understandings of the genetic diversity patterns and their altering in a changing world. The book is aimed to the ones inspired to study and contemplate genetic diversity and to the audience beyond any frames
    Note: English
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  • 3
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535135166 , 9789535135159 , 9789535146735
    Language: Undetermined
    Pages: 1 Online-Ressource (280 p.)
    Keywords: Medical genetics
    Abstract: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis
    Note: English
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  • 4
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535132929 , 9789535132912 , 9789535147367
    Language: Undetermined
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Medical genetics
    Abstract: Congenital defects in humans are of greater concern, and in that line, cystic fibrosis (CF) has been one of the most complex diseases posing treatment challenge till date. Though it is a chronic condition, CF is closely associated with dysfunction of various organ systems of the human body, which in turn results in secondary infections by microbes. Decades of research by scientists worldwide has narrowed down the cause of CF to a single target gene. But the complexity of the disease is the prime impediment to finding a single-shot cure. Fortunately, the multidisciplinary approach toward understanding and management of the CF condition has certainly increased the level of life expectancy among CF patients. In particular, the "omics" and the "systems biology" approach have greatly widened the focal area for better understanding of the disease. This book includes a collection of interesting chapters contributed by eminent scientists around the world who have been striving to improve the life of those affected by CF
    Note: English
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  • 5
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535137184 , 9789535137177 , 9789535140139
    Language: Undetermined
    Pages: 1 Online-Ressource (200 p.)
    Keywords: Medical genetics
    Abstract: Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body
    Note: English
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  • 6
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535134626 , 9789535134619 , 9789535146780
    Language: Undetermined
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Medical genetics
    Abstract: In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence
    Note: English
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  • 7
    ISBN: 9789535135043 , 9789535135036 , 9789535146520
    Language: Undetermined
    Pages: 1 Online-Ressource (328 p.)
    Keywords: Medical genetics
    Abstract: The large potential of RNA sequencing and other "omics" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological areas with remarkable technological advances in the study of systems biology, from microorganisms to precision medicine
    Note: English
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  • 8
    Online Resource
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    [Erscheinungsort nicht ermittelbar] : IntechOpen
    ISBN: 9789535135029 , 9789535134992 , 9789535146636
    Language: Undetermined
    Pages: 1 Online-Ressource (120 p.)
    Keywords: Medical genetics
    Abstract: Phylogenetics aims to study the evolutionary relatedness of living organisms in our planet. Its application is extended to the key areas such as evolution, classification and taxonomy of living organisms; ecology, diversity, and conservation biology of agrobiocenosis; monitoring of pathogen spread, outbreaks and source of transmissions, forensic analyses, etc. Historically, phylogenetics studies were prevalently based on morphological features of species that helped to classify the 'Tree of Life' on Earth. Modern phylogenetics studies, however, rely more heavily on DNA sequences. In this Phylogenetics book, we aimed to present readers the latest developments in phylogenetics studies that highlight multi-kingdom systems, reticulated evolution and conservation biology of living organisms as well as 'omics'-based phylogenetics advances
    Note: English
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