Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • OLC Ethnologie  (23)
  • Englisch  (23)
  • Chinesisch
  • Zhang, Li  (14)
  • Kumar, Sunil  (9)
Datenlieferant
Materialart
Sprache
Erscheinungszeitraum
Verfasser
  • 1
    Artikel
    Artikel
    The Rise of Therapeutic Governing in Postsocialist China (2017)
    Dazugehörige Bände/Artikel
    In:  Medical anthropology : cross-cultural studies in health and illness Vol. 36, No. 1 (2017), p. 6-18
    Details
    ISSN: 0145-9740
    Sprache: Englisch
    Titel der Quelle: Medical anthropology : cross-cultural studies in health and illness
    Publ. der Quelle: London [u.a.] : Taylor & Francis
    Angaben zur Quelle: Vol. 36, No. 1 (2017), p. 6-18
    DDC: 570
    Kurzfassung: In this article, I explore how and why psychological intervention, often in the name of guanai (care), has gradually become a critical tool of managing the population and governing society in postsocialist China. Psychological counselors and experts are becoming a new form of authority, an indispensable part of creating and managing knowable, stable, and governable subjects for the military, the police, schools, and enterprises. 'Therapeutic governing' refers to the adoption of the therapeutic ethos, techniques, and care to improve the management of the work force and to help individuals cope with life in a rapidly changing society. I examine what drives local authorities to pursue this change, and how therapeutic governing takes on a different character and significance given China's unique path. I suggest that incorporating psychotherapeutic intervention into postsocialist governing can simultaneously produce disciplining and nurturing, repressive and unfettering effects in everyday life.
    Anmerkung: Copyright: © 2016 Taylor & Francis 2016
    DOI: 10.1080/01459740.2015.1117079
    URL: Volltext
    URL: http://www.tandfonline.com/doi/abs/10.1080/01459740.2015.1117079
    URL: http://www.ncbi.nlm.nih.gov/pubmed/26575825
    URL: http://search.proquest.com/docview/1767993647
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 2
    Artikel
    Artikel
    Rhizoma Smilacis Glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-κB pathway (2017)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs (2017)
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: (2017)
    DDC: 610
    DOI: 10.1016/j.jep.2017.02.034
    URL: Volltext
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 3
    Artikel
    Artikel
    Between Biopolitical Governance and Care: Rethinking Health, Selfhood, and Social Welfare in East Asia (2017)
    Dazugehörige Bände/Artikel
    In:  Medical anthropology : cross-cultural studies in health and illness Vol. 36, No. 1 (2017), p. 1-5
    Details
    ISSN: 0145-9740
    Sprache: Englisch
    Titel der Quelle: Medical anthropology : cross-cultural studies in health and illness
    Publ. der Quelle: London [u.a.] : Taylor & Francis
    Angaben zur Quelle: Vol. 36, No. 1 (2017), p. 1-5
    DDC: 570
    Kurzfassung: Medical Anthropology Between Biopolitical Governance and Care: Rethinking Health, Selfhood, and Social Welfare in East Asia
    Anmerkung: Copyright: © 2016 Taylor & Francis 2016
    DOI: 10.1080/01459740.2016.1158178
    URL: Volltext
    URL: http://www.tandfonline.com/doi/abs/10.1080/01459740.2016.1158178
    URL: http://search.proquest.com/docview/1846828451
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 4
    Artikel
    Artikel
    Epigallocatechin-3-gallate: An efficient alternative to synthetic antioxidants and preservatives in cheese (2017)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 47, No. 2 (2017), p. 191
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 47, No. 2 (2017), p. 191
    DDC: 630
    Kurzfassung: Purpose The purpose of the study was to explore the possibility of utilization of epigallocatechin-3-gallate (EGCG) as a novel preservative in cheese. EGCG has strong antioxidant and antimicrobial properties and may be commercially exploited as a natural antioxidant and preservative in cheese like products which are highly susceptible to lipid oxidation. Design/methodology/approach The study was conducted to evaluate the possibility of using EGCG as a natural antioxidant and preservative in cheese. Kalari, a hard and dry cheese, was used as a model and treated with different concentrations of EGCG (0, 0.05 and 0.10 per cent) and aerobically packaged within low-density polyethylene pouches and assessed for oxidative stability and storage quality under refrigerated (4 ± 1°C) conditions. Findings EGCG showed a significant (p 〈 0.05) effect on the lipid oxidative stability as the treated products exhibited significantly (p 〈 0.05) lower thiobarbituric acid reactive substances (milligram malonaldehyde/kg) values. A significant (p 〈 0.05) effect was also observed on the microbiological characteristics of the products, as treated products showed significantly (p 〈 0.05) lower values for total plate count (log cfu/g), psychrophilic count (log cfu/g), yeast and mould count (log cfu/g) and free fatty acid (% oleic acid) values. Coliforms (log cfu/g) were not detected throughout the storage period. Significantly (p 〈 0.05) higher scores were observed for various sensory parameters of the treated products. EGCG successfully improved the oxidative stability and storage quality of Kalari. Originality/value The results suggest that EGCG might be useful to the dairy industry as an efficient alternative to synthetic antioxidants and preservatives.
    URL: https://search.proquest.com/docview/1884370680
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 5
    Artikel
    Artikel
    Terpene glycoside component from Moutan Cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs (2016)
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: (2016)
    DDC: 610
    DOI: 10.1016/j.jep.2016.09.043
    URL: Volltext
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 6
    Artikel
    Artikel
    Total saponins of panaxnotoginseng promotes lymphangiogenesis by activation VEGF-C expression of lymphatic endothelial cells (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 193 (2016), p. 293-302
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 193 (2016), p. 293-302
    DDC: 610
    DOI: 10.1016/j.jep.2016.08.032
    URL: Volltext
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 7
    Artikel
    Artikel
    The dosage-toxicity-efficacy relationship of kansui and licorice in malignant pleural effusion rats based on factor analysis (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 186 (2016), p. 251-256
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 186 (2016), p. 251-256
    DDC: 610
    Kurzfassung: The root of Euphorbia kansui T.P. Wang (Euphorbiaceae), a well-known traditional Chinese medicine (TCM) with certain toxicity, is known as Gan sui (Chinese: ) or kansui. It has been used to treat edema, ascites, asthma, and etc. Licorice is the root of Glycyrrhiza uralensis Fisch. or Glycyrrhiza inflate Bat. or Glycyrrhiza glabra L., Leguminosae. It is a widely used herbal medicine native to southern Europe and parts of Asia as an herbal medicine and natural sweetener. Kansui cannot be co-used with licorice, which is recorded in "eighteen incompatible" medicaments in many monographs of TCM. The present study was conducted to investigate the dosage-toxicity-efficacy relationship of the co-use of kansui and licorice and to explore its regularity of the toxicity and efficacy change. Malignant pleural effusion rats were used and randomly divided into the normal control group, model group, positive control group (furosemide), kansui group, licorice group, and kansui-licorice groups with different ratios (kansui: licorice: 4:1, 2:1, 1:1, 0.5:1, 0.25:1, 0.1:1). Each group was adopted simultaneously to investigate the characteristic of toxicity and effect by measuring the pleural fluid and urine volumes, serum biochemical indexes, and serum TNF-α, IL-2 and IFN-γ levels. The factor analytic approach was used to analyze the dosage-toxicity-efficacy relationship between kansui and licorice. Two common factors were extracted from 8 indexes concerning toxicity and 5 indexes concerning efficacy. And the total factors related to toxicity (Ft) and efficacy (Fe) were calculated. The curved line of Ft indicated that the toxicity was increased along with the dose increase in licorice. The curved line of Fe indicated that the efficacy was decreased along with the dose increase in licorice. The intersection of these two lines was between the ratios of 2:1 and 1:1, and was deemed the flex point of the dosage-toxicity-efficacy. Kansui demonstrated a certain efficacy in treating malignant pleural effusion, and the efficacy could be weakened by the co-use of licorice, even causing serious toxicity at the given ratio. The ratio between 2:1 and 1:1 (kansui: licorice) was deemed the flex point of the dosage-toxicity-efficacy of kansui and licorice. The results will be helpful for their better utilization and development.
    Anmerkung: Copyright: © Elsevier Ireland Ltd , Copyright: Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2016.04.012
    URL: Volltext
    URL: http://www.sciencedirect.com/science/article/pii/S0378874116302033
    URL: http://www.ncbi.nlm.nih.gov/pubmed/27084456
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 8
    Artikel
    Artikel
    Protection of tauroursodeoxycholic acid on high glucose-induced human retinal microvascular endothelial cells dysfunction and streptozotocin-induced diabetic retinopathy rats (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 185 (2016), p. 162-170
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 185 (2016), p. 162-170
    DDC: 610
    Kurzfassung: Tauroursodeoxycholic acid (TUDCA), one of the main ingredients from bear gall which hold "Clearing heat and detoxification, Removing liver fire for improving eyesight" functions, is formed by the conjugation of ursodeoxycholic acid (UDCA) with taurine. However, the limited information of TUDCA on protecting diabetic retinopathy (DR) has been known. The present study was conducted to evaluate the protection of TUDCA on high glucose-induced human retinal microvascular endothelial cells (HRMECs) dysfunction and streptozotocin (STZ)-induced diabetic retinopathy (DR) rats and the possible mechanism underlying was also explored. The proliferation of high glucose-induced HRMECs was determined by MTT assay. DR rats' model was established by an administration of high-glucose-fat diet and an intraperitoneal injection of STZ (30mg/kg). The cell supernatant and rats' serum were collected for the assays of NO content by ELISA kits. Retinas were stained with hematoxylin and eosin (HE) to observe pathological changes. Immunohistochemical assay was applied to examine the protein expression of ICAM-1, NOS, NF-κB p65 and VEGF in rat retinas. Furthermore, western blot analysis was carried out to examine the protein expression of ICAM-1, NOS, NF-κB p65 and VEGF in high glucose-induced HRMECs. After treating with TUDCA, high glucose-induced HRMECs proliferation could be significantly inhibited. TUDCA (5.0μM, 25.0μM and 125.0μM) could decrease NO content in high glucose-induced HRMECs. Furthermore, TUDCA (500mg/kg/d and 250mg/kg/d) also decrease NO content in serum of DR rats. Additionally, both immunocytochemistry analysis and western blot analysis showed that the over-expression of ICAM-1, NOS, NF-κB p65 and VEGF were significantly decreased by TUDCA. The data indicated that TUDCA could ameliorate DR by decreasing NO content and down-regulating the protein expression of ICAM-1, NOS, NF-κB p65 and VEGF. Thus, our experimental results suggested that TUDCA might be a potential drug for the prevention and treatment of DR.
    Anmerkung: Copyright: © Elsevier Ireland Ltd , Copyright: Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2016.03.026
    URL: Volltext
    URL: http://www.sciencedirect.com/science/article/pii/S0378874116301337
    URL: http://www.ncbi.nlm.nih.gov/pubmed/26988565
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 9
    Artikel
    Artikel
    Terpene glycoside component from Moutan Cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 193 (2016), p. 433-444
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 193 (2016), p. 433-444
    DDC: 610
    DOI: 10.1016/j.jep.2016.09.043
    URL: Volltext
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 10
    Artikel
    Artikel
    Anti-inflammatory effect of volatile oil from Schizonepeta tenuifolia on carrageenin-induced pleurisy in rats and its application to study of appropriate harvesting time coupled with multi-attribute comprehensive index method (2016)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 194 (2016), p. 580-586
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 194 (2016), p. 580-586
    DDC: 610
    DOI: 10.1016/j.jep.2016.10.045
    URL: Volltext
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 11
    Artikel
    Artikel
    The Rise of Therapeutic Governing in Postsocialist China (2016)
    Dazugehörige Bände/Artikel
    In:  Medical anthropology : cross-cultural studies in health and illness Vol. 35, No. 2 (2016), p. 119
    Details
    ISSN: 0145-9740
    Sprache: Englisch
    Titel der Quelle: Medical anthropology : cross-cultural studies in health and illness
    Publ. der Quelle: London [u.a.] : Taylor & Francis
    Angaben zur Quelle: Vol. 35, No. 2 (2016), p. 119
    DDC: 570
    Kurzfassung: In this article, I explore how and why psychological intervention, often in the name of guanai (care), has gradually become a critical tool of managing the population and governing society in postsocialist China. Psychological counselors and experts are becoming a new form of authority, an indispensable part of creating and managing knowable, stable, and governable subjects for the military, the police, schools, and enterprises. 'Therapeutic governing' refers to the adoption of the therapeutic ethos, techniques, and care to improve the management of the work force and to help individuals cope with life in a rapidly changing society. I examine what drives local authorities to pursue this change, and how therapeutic governing takes on a different character and significance given China's unique path. I suggest that incorporating psychotherapeutic intervention into postsocialist governing can simultaneously produce disciplining and nurturing, repressive and unfettering effects in everyday life.
    Anmerkung: Copyright: © 2016 Taylor & Francis 2016
    DOI: 10.1080/01459740.2015.1117079
    URL: Volltext
    URL: http://www.tandfonline.com/doi/abs/10.1080/01459740.2015.1117079
    URL: http://www.ncbi.nlm.nih.gov/pubmed/26575825
    URL: http://search.proquest.com/docview/1767993647
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 12
    Artikel
    Artikel
    Urine and plasma metabonomics coupled with UHPLC-QTOF/MS and multivariate data analysis on potential biomarkers in anemia and hematinic effects of herb pair Gui-Hong (2015)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 170 (2015), p. 175-183
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 170 (2015), p. 175-183
    DDC: 610
    Kurzfassung: The compatibility of Angelicae Sinensis Radix (Danggui) and Carthami Flos (Honghua), a famous herb pair Gui-Hong, can produce synergistic and complementary hematinic effects. Our previous studies have indicated that Gui-Hong has therapeutic potential treatment in hemolytic and aplastic anemia (HAA). The present study aimed to investigate the hematinic effects of Danggui, Honghua and Gui-Hong on HAA rats induced by acetyl phenylhydrazine (APH) and cyclophosphamide (CP) and to explore the underlying hematinic regulation mechanisms. Rats were divided into 5 groups, and drugs were administered by oral gavage one time each day for continuous 7 days from the experiment began. Urine and plasma were analyzed by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UHPLC-QTOF/MS). Partial least-squares discriminate analysis (PLS-DA) models were built to evaluate the therapeutic effects of Danggui, Honghua and Gui-Hong. Pearson correlation matrix analysis method was used to discover the correlations between potential biomarkers and biochemical indicators of HAA rats. Seven potential biomarkers contribute to the separation of model group and control group were tentatively identified. The levels of l-kynurenine, phenylalanine, nicotinic acid and sphingosine increased significantly (P〈0.05) in HAA rats, while the levels of l-isoleucine, l-tyrosine and serotonin decreased significantly (P〈0.05) in comparison with control rats. Those endogenous metabolites were chiefly involved in phenylalanine, tyrosine and tryptophan biosynthesis, valine, leucine and isoleucine biosynthesis, tryptophan metabolism and tyrosine metabolism. The metabolic deviations could be regulated closer to normal level after Danggui, Honghua and Gui-Hong intervention. In term of hematinic effects, Gui-Hong was the most effective as shown by the relative distance in PLS-DA score plots and relative intensity of potential biomarkers. The result reflected the synergic action between Danggui and Honghua. The above results were found to be reasonable in explaining the hematinic effects mechanism of Gui-Hong. The results of routine blood, urinary metabolic pattern and plasma metabolic pattern show the Danggui, Honghua and Gui-Hong groups are moving toward the control group and the HAA was being prevented and alleviated. The effect of Gui-Hong group is more remarkable than Danggui and Honghua groups. Some potential biomarkers like l-kynurenine, phenylalanine, l-isoleucine, l-tyrosine, serotonin, nicotinic acid and sphingosine have been found and identified. The work shows that the metabonomics method is a promising tool in the efficacy and mechanism research of traditional Chinese medicines.
    Anmerkung: Copyright: Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2015.05.019
    URL: Volltext
    URL: http://www.ncbi.nlm.nih.gov/pubmed/25985767
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 13
    Artikel
    Artikel
    Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis (2015)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 162 (2015), p. 207-214
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 162 (2015), p. 207-214
    DDC: 610
    Kurzfassung: HuangqinTang (HQT) is a traditional Chinese formula which is composed of Scutellaria baicalensis Georgi, Paeonia lactiflora Pall, Glycyrrhiza uralensis Fisch, and Ziziphus jujube Mill. HQT has been used in China for a wide range of disorders, especially in gastrointestinal inflammation with symptoms of nausea, vomiting, diarrhea, abdominal cramps and so on. To investigate the protective effects of HQT extract on 2, 4, 6-trinitrobenzenesulfonic acid (TNBS) induced colitis in mice. Different doses of HQT extract (1, 2 and 4 g/kg/day) and salicylazosulfapyridine (SASP, 500 mg/kg/day) were administered by gavage for 7 days after the induction of colitis with TNBS. The effects were studied by macroscopic score, histological analysis, immunohistochemical study of Cyclo-oxygenase-2 protein expression, as well as by determination of inflammation markers such as myeloperoxidase (MPO) and mRNA expression levels of pro-inflammatory cytokines, including TNF-α, IL-1β and IL-6. In TNBS induced group, mice body weight decreased gradually and did not recover at the end of the experiment, as compared with that of control group (p〈0.01). Edema and redness were also discovered in the colons profoundly and scores representing inflammation were all high in this group (p〈0.01). The level of colonic MPO activity and the tissue levels of TNF-α, IL-1β and IL-6 were markedly increased (p〈0.01). The mice treated with HQT extract and SASP recovered significantly compared with the TNBS group (p〈0.01). Our results suggested that the efficacy of HQT extract, especially at the higher dose, was analogous to that of SASP, which implicated its potential application as a natural alternative medicine in colitis treatment.
    Anmerkung: Copyright: Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2014.12.039
    URL: Volltext
    URL: http://www.ncbi.nlm.nih.gov/pubmed/25576893
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 14
    Artikel
    Artikel
    3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol induces apoptosis in intestinal epithelial cells of rats via mitochondrial pathway (2015)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 174 (2015), p. 331
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 174 (2015), p. 331
    DDC: 610
    Kurzfassung: Euphorbia kansui is a traditional Chinese medicine widely used for the treatment of edema, ascite and asthma in China for centuries. However, its serious gastrointestinal toxicity restricted its safe clinical application. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol (3EZ,20Ac-ingenol), a diterpenoid compound derived from kansui, has obvious gastrointestinal cytotoxicity in cells. Until now, its gastrointestinal cytotoxic mechanism is mostly unknown. This study focused on elucidating the cytotoxic mechanism of 3EZ,20Ac-ingenol in intestinal epithelial cells of rats (IEC-6 cells) to guide safer application of this herb in clinic. 3EZ,20Ac-ingenol was isolated from the EtOAc extract of kansui. Cell morphology was detected by inverted phase contrast microscope and transmission electron microscope (TEM). Cell apoptosis was examined by Annexin V-FITC/PI dual-staining or Hoechst staining. ROS generation was detected with DCFH-DA staining by laser scanning confocal microscope. MMP change was examined with JC-1 staining by high content screening (HCS). Further, the release of cytochrome c, the expressions of Bax, Bcl-2, AIF and Apaf-1 were analyzed by western blot and the activities of caspase-3, 8, 9 were determined by ELISA. Additionally, cell cycle analysis was performed to detect the effects of 3EZ,20Ac-ingenol on cell cycle in IEC-6 cells by flow cytometry. The study showed that 3EZ,20Ac-ingenol significantly reduced IEC-6 cells viability in a dose-dependent manner and the IC50 value was 5.74μg/mL. Consistently, 3EZ,20Ac-ingenol could elevate reactive oxygen species (ROS), disrupt mitochondrial membrane potential (MMP), induce the release of cytochrome c from mitochondria to cytosol, enhance the expressions of Bax, AIF and Apaf-1, suppress the expression of Bcl-2, then activate caspase-3, 8, 9 cascade, and subsequently result in apoptosis. Additionally, 3EZ,20Ac-ingenol also could cause G2/M phase arrest in IEC-6 cells. The results indicated that 3EZ,20Ac-ingenol induced the cytotoxicity of IEC-6 cells depends on induction of cell apoptosis via mitochondrial pathway and cell cycle arrest.
    Anmerkung: Copyright: Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2015.08.036
    URL: Volltext
    URL: http://www.ncbi.nlm.nih.gov/pubmed/26318745
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 15
    Artikel
    Artikel
    The quality and storage stability of chicken patties prepared with different additives (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 5 (2015), p. 728-739
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 5 (2015), p. 728-739
    DDC: 630
    Kurzfassung: Purpose – The purpose of the present study was to evaluate the effect of green tea extract, fig and red pepper on the quality characteristics of chicken patties during refrigerated storage. Design/methodology/approach – The study was designed to evaluate the effect of green tea extract, fig and red pepper on the storage quality parameters of chicken patties. The products were developed by incorporating optimum level of green tea extract (400 mg/kg), fig (4 per cent) and red pepper (10 per cent) separately and were aerobically packaged in low-density polyethylene pouches and assessed for various storage-quality parameters under refrigerated (4 ± 1°C) conditions for 21 days of storage. The products were evaluated for various physicochemical, microbiological and sensory parameters at regular intervals of 0, 7, 14 and 21 days. Findings – A significant (p 〈 0.05) effect of green tea extract, fig and red pepper was observed on the pH and TBARS (mg malonaldehyde/kg) values of the chicken patties. A significant (p 〈 0.05) effect was also observed on the microbiological characteristics as the products incorporated with green tea extract, fig and red pepper showed significantly (p 〈 0.05) lower values for total plate count, psychrophillic count and yeast and mould count during the period of storage. Coliforms were not detected throughout the period of storage. Significantly (p 〈 0.05) higher scores were observed for various sensory parameters of the products incorporated with green tea extract, fig and red pepper. Originality/value – Green tea extract (400 mg/kg), fig (4 per cent) and red pepper (10 per cent) successfully improved the oxidative stability and storage quality of the products during refrigerated (4 ± 1°C) storage and may be commercially exploited to improve the storage quality of muscle foods without adversely affecting the sensory quality of the products.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-01-2015-0009
    URL: Volltext
    URL: http://search.proquest.com/docview/1709343005
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 16
    Artikel
    Artikel
    Effect of Aloe vera on the lipid stability and storage quality of chicken nuggets (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 1 (2015), p. 54-67
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 1 (2015), p. 54-67
    DDC: 630
    Kurzfassung: Purpose – The purpose of this study was to explore the potential of Aloe vera as a novel source of natural antioxidant and preservative in the muscle foods and to evaluate the effect of Aloe vera on the storage quality of aerobically packaged chicken nuggets. Design/methodology/approach – The Aloe vera pulp was incorporated at various levels, namely, 0, 5, 10 and 15 per cent, replacing lean meat in the formulation. The products were analyzed for proximate composition, physicochemical and sensory parameters. Chicken nuggets incorporated with optimum level of Aloe vera (10 per cent) along with control nuggets (0 per cent Aloe vera) were aerobically packaged and assessed for lipid oxidation, physicochemical and microbiological characteristics under refrigerated (4°C) conditions. Findings – pH, crude protein, ether extract and ash content of the nuggets showed significant (p 〈 0.05) decreasing trend with increasing levels of Aloe vera; however, there was a significant (p 〈 0.05) increase in the moisture content, emulsion stability and cooking yield. Aloe vera-enriched nuggets showed significantly (p 〈 0.05) lower values than control nuggets for almost all the lipid oxidation and microbiological parameters, i.e. free fatty acid, thiobarbituric acid-reactive substances value, total plate count, psychrophillic count and yeast and mould count. No significant (p 〉 0.05) difference was observed in the sensory parameters of the Aloe vera-enriched nuggets and the control samples throughout the period of storage. Originality/value – The paper has demonstrated the use of Aloe vera as a potential natural antioxidant without any marginal decline in the sensorial characteristics and nutritive value of the muscle foods.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-04-2014-0034
    URL: Volltext
    URL: http://search.proquest.com/docview/1650518951
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 17
    Artikel
    Artikel
    Effect of Ocimum sanctum Linn (Tulsi) on the oxidative stability and storage quality of chicken sausages (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 4 (2015), p. 510-523
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 4 (2015), p. 510-523
    DDC: 630
    Kurzfassung: Purpose – The purpose of this paper was to explore the possibility of utilization of Ocimum sanctum Linn (Tulsi) leaf extract as a natural preservative in muscle foods. The products incorporated with Ocimum sanctum leaf extract were assessed for various oxidative stability and storage quality parameters. Design/methodology/approach – The Ocimum sanctum leaf extract was incorporated at 300 mg/kg level in the formulation. Chicken sausages incorporated with Ocimum sanctum leaf extract along with control samples were aerobically packaged in low-density polyethylene pouches and assessed for lipid oxidation, physicochemical, microbiological and sensory characteristics under refrigerated (4 ± 1°C) conditions. Findings – Ocimum sanctum leaf extract showed a significant (p 〈 0.05) effect on the lipid stability, as the treated products exhibited significantly (p 〈 0.05) lower thiobarbituric acid reactive substances (mg malonaldehyde/kg) and free fatty acid (% oleic acid) values in comparison to control. A significant (p 〈 0.05) effect was also observed on the microbiological characteristics of the products, as the treated products showed significantly (p 〈 0.05) lower values for total plate count, psychrophilic count and yeast and mould count. Significantly, (p 〈 0.05) higher scores were also observed for various sensory parameters of the treated products. Originality/value – The paper has demonstrated the use of Ocimum sanctum leaf extract as a potential natural preservative, as it successfully improved the oxidative stability and storage quality of the products during refrigerated (4 ± 1°C) storage and may be commercially exploited as a natural preservative in muscle foods.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-01-2015-0002
    URL: Volltext
    URL: http://search.proquest.com/docview/1686979420
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 18
    Artikel
    Artikel
    Effect of lemon peel extract on the oxidative stability and storage quality of Tabak-Maz, traditional fried mutton ribs (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 5 (2015), p. 662-676
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 5 (2015), p. 662-676
    DDC: 630
    Kurzfassung: Purpose – The purpose of this study is to explore the possibility of utilization of lemon peel extract as a natural antioxidant source in muscle foods. The products incorporated with lemon peel extract were assessed for various oxidative stability and storage quality parameters. Design/methodology/approach – The study was designed to evaluate the effect of lemon peel extract on the oxidative stability and storage quality of Tabak-Maz, a popular traditional meat product. The products were prepared and treated with different concentrations of lemon peel extract (0.5, 1, 1.5 per cent) and were aerobically packaged in low-density polyethylene pouches and assessed for lipid stability and storage quality parameters under refrigerated (4 ± 1°C) conditions. Findings – Lemon peel extract showed a significant (p 〈 0.05) effect on the lipid stability of the products as the treated products exhibited significantly (p 〈 0.05) lower thiobarbituric acid-reactive substances (TBARS) (mg malonaldehyde/kg) and free fatty acid (FFA) (per cent oleic acid) values for the entire period of storage. A significant (p 〈 0.05) effect was also observed on the microbiological characteristics of the products, as lemon peel extract treated products showed significantly (p 〈 0.05) lower values for total plate count, psychrophillic count and yeast and mould count throughout the period of storage. Coliforms were not detected throughout the period of storage. Significantly (p 〈 0.05) higher scores were observed for various sensory parameters of the treated products. Originality/value – Lemon peel extract successfully improved the oxidative stability and storage quality of Tabak-Maz during refrigerated (4 ± 10°C) storage and may be commercially exploited as a natural antioxidant source in muscle foods.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-01-2015-0006
    URL: Volltext
    URL: http://search.proquest.com/docview/1709342887
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 19
    Artikel
    Artikel
    Bioactive peptides from egg: a review (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 2 (2015), p. 190-212
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 2 (2015), p. 190-212
    DDC: 630
    Kurzfassung: Purpose – The aim of the article was to focus on various peptides identified in the egg and their probable application as novel ingredients in the development of functional food products. Bioactive peptides of egg origin have attracted increasing interest as one of the prominent candidates for development of various health-promoting functional and designer foods. Design/methodology/approach – Traditionally known as a source of highly valuable proteins in human nutrition, eggs are nowadays also considered as an important source of many bioactive peptides which may find wide application in medicine and food production. These specific protein fragments from egg proteins which, above and beyond their nutritional capabilities, have a positive impact on the body’s function or condition by affecting the digestive, endocrine, cardiovascular, immune and nervous systems, and may ultimately influence health. Findings – Several peptides that are released in vitro or in vivo from egg proteins have been attributed to different health effects, including antihypertensive effects, antimicrobial properties, antioxidant activities, anticancer activity, immunomodulating activity, antiadhesive properties and enhancement of nutrient absorption and/or bioavailability. Extensive research has been undertaken to identify and characterize these biologically active peptides of egg origin which has changed the image of egg as a new source of biologically active ingredients for the development of functional foods with specific benefits for human health and treatment and prevention of diseases. Originality/value – The paper mainly describes the above-stated properties of bioactive peptides derived from egg proteins.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-10-2014-0088
    URL: Volltext
    URL: http://search.proquest.com/docview/1661553181
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 20
    Artikel
    Artikel
    Effect of sorghum bicolour and clove oil on the quality characteristics and storage quality of aerobically packaged chevon cutlets (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 1 (2015), p. 145-163
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 1 (2015), p. 145-163
    DDC: 630
    Kurzfassung: Purpose – This paper aims to focus on the effect of Sorghum bicolour on the quality characteristics of chevon cutlets and to evaluate the effect of clove oil on the storage quality of aerobically packaged chevon cutlets. Design/methodology/approach – Three levels of sorghum flour, namely, 2, 4 and 6 per cent, were incorporated in the formulation, and the products developed were assessed for various physicochemical, sensory, texture and colour parameters. Chevon cutlets containing optimum level of sorghum flour were treated with clove oil (100 ppm) and evaluated for storage quality for 15 days under refrigerated conditions (4 ± 1°C). The products were analysed for various physicochemical, microbiological and sensory parameters. Findings – Crude fibre, texture parameters, i.e. hardness, adhesiveness, springiness, cohesiveness, chewiness, gumminess and product redness value, showed significant (p 〈 0.05) increasing trend, whereas moisture per cent, fat content and overall acceptability decreased significantly (p 〈 0.05) with increasing levels of incorporation. Chevon cutlets containing 6 per cent sorghum flour were optimized as best. Thiobarbituric acid-reactive substance value (mg malonaldehyde/kg), total plate count (cfu/g) and psychrophillic count (cfu/g) showed a significant increasing trend (p 〈 0.05), whereas all the sensory parameters decreased significantly (p 〈 0.05) with increasing days of storage. The products were successfully stored for 10 days under refrigerated conditions (4 ± 1°C) without marked loss in quality. Originality/value – The paper has demonstrated the potential of sorghum as a fibre source in the development of designer chevon cutlets and effect of clove oil on the storage quality of aerobically packaged chevon cutlets.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-02-2014-0017
    URL: Volltext
    URL: http://search.proquest.com/docview/1650518918
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 21
    Artikel
    Artikel
    Effect of different fiber sources and tert-butylhydroquinone on the quality characteristics of chicken harrisa, a meat based product (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 6 (2015), p. 930-943
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 6 (2015), p. 930-943
    DDC: 630
    Kurzfassung: Purpose – This paper aims to evaluate the effect of different fiber sources and tert-butylhydroquinone (TBHQ) on the quality characteristics of chicken harrisa. Design/methodology/approach – An attempt was made to develop fiber-enriched chicken harrisa, a meat-based product, by incorporating optimum level of different fiber sources, viz., oat bran (10 per cent) or wheat bran (10 per cent) or barley bran (5 per cent). The products developed with optimized level of fiber were further treated with TBHQ (200 ppm) and were aerobically packaged in low-density polyethylene pouches along with control and assessed for various storage quality parameters under refrigerated (4 ± 1°C) conditions. The products were evaluated for various physicochemical, microbiological and sensory parameters at regular intervals of 0, 7, 14 and 21 days. Findings – A significant (p 〈 0.05) increase was observed in the fiber content of the products prepared with oat bran (10 per cent) or wheat bran (10 per cent) or barley bran (5 per cent). TBHQ showed a significant (p 〈 0.05) effect on the lipid oxidative stability, as the treated products exhibited significantly (p 〈 0.05) lower thiobarbituric acid-reactive substance (mg malonaldehyde/kg) values for the entire period of storage. No significant (p 〉 0.05) effect was observed on the microbiological characteristics of the products. Sensory parameters showed significant (p 〈 0.05) decreasing trend for control as well as TBHQ-treated products throughout the period of storage; however, significantly (p 〈 0.05) higher scores were observed for treated products in comparison to control. Originality/value – Fiber-enriched chicken harrisa was developed by incorporating oat bran (10 per cent) or wheat bran (10 per cent) or barley bran (5 per cent) in the formulation. TBHQ successfully improved the lipid oxidative stability and storage quality of fiber-enriched chicken harrisa during refrigerated (4 ± 1°C) storage and may be commercially exploited to improve the storage quality of the product.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-05-2015-0062
    URL: Volltext
    URL: http://search.proquest.com/docview/1735637285
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 22
    Artikel
    Artikel
    Utilization of pomegranate seed powder and tomato powder in the development of fiber-enriched chicken nuggets (2015)
    Dazugehörige Bände/Artikel
    In:  Nutrition & food science Vol. 45, No. 5 (2015), p. 793-807
    Details
    ISSN: 0034-6659
    Sprache: Englisch
    Titel der Quelle: Nutrition & food science
    Publ. der Quelle: Bingley : Emerald
    Angaben zur Quelle: Vol. 45, No. 5 (2015), p. 793-807
    DDC: 630
    Kurzfassung: Purpose – The purpose of this study is to evaluate the possibility of utilization of pomegranate seed powder and tomato powder in the development of fiber-enriched chicken nuggets. Design/methodology/approach – The study was designed to incorporate and evaluate the effect of pomegranate seed powder and tomato powder on the quality characteristics of the chicken nuggets. The products were developed by incorporating different levels of pomegranate seed powder (1, 2, 3 per cent) and tomato powder (1, 2, 3 per cent) separately and were analyzed for various physicochemical and sensory parameters. Findings – The pomegranate seed powder and tomato powder significantly (p 〈 0.05) increased the fiber content of the chicken nuggets besides improving various sensory attributes of the products. A significant (p 〈 0.05) effect of the pomegranate seed powder was observed on the pH, emulsion stability, cooking yield and proximate parameters of the chicken nuggets. Tomato powder also showed a significant (p 〈 0.05) effect on the emulsion stability, moisture and fat content of the products. No significant (p 〉 0.05) effect of tomato was observed on the pH and cooking yield of the products. Originality/value – Fiber-enriched chicken nuggets could be developed by incorporating pomegranate seed powder and tomato powder in the formulation besides improving various sensory attributes of the products.
    Anmerkung: Copyright: © Emerald Group Publishing Limited
    DOI: 10.1108/NFS-05-2015-0066
    URL: Volltext
    URL: http://search.proquest.com/docview/1709343052
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
  • 23
    Artikel
    Artikel
    Comparison on hypoglycemic and antioxidant activities of the fresh and dried Portulaca oleracea L. in insulin-resistant HepG2 cells and streptozotocin-induced C57BL/6J diabetic mice (2015)
    Dazugehörige Bände/Artikel
    In:  Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs Vol. 161 (2015), p. 214-223
    Details
    ISSN: 0378-8741
    Sprache: Englisch
    Titel der Quelle: Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs
    Publ. der Quelle: Shannon : Elsevier Science Ireland
    Angaben zur Quelle: Vol. 161 (2015), p. 214-223
    DDC: 610
    Kurzfassung: Fresh Portulaca oleracea L. (family: Portulacaceae; POL) has been used as a folk medicine for the treatment of diabetes mellitus for a long time. More bioactive components with higher activity could be retained in fresh medicinal herbs compared to the dried ones. The present study was conducted to compare different antidiabetic activity between fresh and dried POL, including hypoglycemic and antioxidant activities both in vivo and in vitro. Furthermore, in order to explore which components were responsible for the antidiabetic activity, the difference on chemical components between fresh and dried POL was analyzed and compared. Insulin-resistant HepG2 cells induced by insulin were used to evaluate the promoting effect of the fresh and dried POL on glucose utilization in vitro. Streptozotocin (STZ)-induced C57BL/6J diabetic mice were used to compare the differences on hypoglycemic and antioxidant activities of fresh and dried POL, including the fasting blood glucose, glucose tolerance, serum insulin level, malondialdehyde (MDA) level and superoxide dismutase (SOD) activity in vivo. UPLC/Q-TOF-MS method was performed to analyze the difference of antidiabetic components between fresh and dried POL. Compared with the dried POL extract, the fresh POL extract significantly increased the consumption of extracellular glucose in insulin-resistant HepG2 cells (P〈0.05). In STZ-induced C57BL/6J diabetic mice, both fresh and dried extracts decreased markedly the fasting blood glucose (FBG) levels, and improved significantly oral glucose tolerance test (OGTT), as well as enhanced significantly insulin secretion and antioxidative activities (P〈0.05; P〈0.01). Furthermore, the fresh extract showed stronger antidiabetic activity (P〈0.05). The UPLC/Q-TOF-MS analysis results also revealed that the relative contents of polyphenols and alkaloids in the fresh herbs were more abundant than those in the dried POL. Our results indicated that both fresh and dried POL possessed antidiabetic activities, besides stronger activity was observed in the fresh herb. These findings provided evidence for the application and development of fresh POL in the treatment of diabetes mellitus.
    Anmerkung: Copyright: Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
    DOI: 10.1016/j.jep.2014.12.002
    URL: Volltext
    URL: http://www.ncbi.nlm.nih.gov/pubmed/25523372
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel
    OLC Ethnologie
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...