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  • Unbestimmte Sprache  (4)
  • 2005-2009  (4)
  • 1970-1974
  • Firenze : Firenze University Press  (4)
  • Medicine  (4)
  • 1
    Online-Ressource
    Online-Ressource
    Firenze : Firenze University Press
    ISBN: 9788884539465 , 9788884539458 , 9788892737686
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (126 p.)
    Serie: Premio Tesi di Dottorato
    Schlagwort(e): Medicine
    Kurzfassung: Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISBN: 9788884539052 , 9788884539045 , 9788892737891
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (192 p.)
    Serie: Premio Tesi di Dottorato
    Schlagwort(e): Medicine
    Kurzfassung: Purinergic nucleotides and nucleosides (ATP, ADP, AMP and adenosine) are essential intracellular metabolites involved in a number of cellular processes, from energy supply to protein phosphorylation. However, in the last years, several studies demonstrated their involvement in cell signalling by the activation of specific membrane receptors (P1 and P2) and their role as neurotransmitters began to be investigated. The present work was aimed to clarify the effects of purinergic neurotransmission in different cell systems by using electrophysiological techniques. Relevant results of this research include the observation that P1 and P2 receptors play a deleterious role during "in vitro" ischemia in the rat brain, and the first demonstration of P2 receptor expression and function in a line of adult human mesenchymal stem cells
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    ISBN: 9788884536112 , 9788884536129 , 9788892738720
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (484 p.)
    Serie: Atti
    Schlagwort(e): Medicine ; Medical equipment & techniques ; Nursing
    Kurzfassung: This book collects together 46 papers presented at the Third Biennial Conference of i-Rec, International Group for the Diffusion of Research and Information on Post-Disaster Reconstruction. The various sections of the book cover the technical and administrative aspects of housing and other buildings after disaster. The approach to post-disaster shelter and reconstruction exemplified by this volume is fully interdisciplinary. A very wide range of perspectives is covered, including the disciplines and sub-disciplines of seismic and structural engineering, architecture, applied geography and geology, environmental psychology, paediatrics, development studies, economics, medicine and public health, management studies and political science. The volume is also intended to commemorate the 40th anniversary of the floods that severely damaged Florence in 1966 and did terrible damage to priceless art treasures
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Online-Ressource
    Online-Ressource
    Firenze : Firenze University Press
    ISBN: 9788892739383
    Sprache: Unbestimmte Sprache
    Seiten: 1 Online-Ressource (254 p.)
    Serie: Electronica
    Schlagwort(e): Medicine
    Kurzfassung: TOX is a manual aimed primarily at the Toxicology courses of the Faculty of Pharmacy and Science, that can also be profitably utilised by students following different degree courses in other Faculties (Medicine, Agriculture, Engineering)and by anyone else looking for a thorough but succinct overview of toxicological questions. TOX covers the principal sectors of general toxicology (acute and chronic toxicity, mutagenesis, teratogenesis, carcinogenesis, reproductive toxicity, oxidative damage, epidemiological methods), specialist toxicology(dietary toxicity, tobacco smoke, pesticides, N-nitroso compounds, heterocyclic amines and aromatic amines toxicity) and environmental toxicology (environmental estrogens, PAH, heavy metals, dioxins and polychlorinated di-benzo-furans, water and air pollution)
    Anmerkung: English
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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