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  • Pharmacology  (54)
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  • 1
    Online Resource
    Online Resource
    New Insights into the Future of Pharmacoepidemiology and Drug Safety (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839685972 , 9781839685965 , 9781839685989
    Language: English
    Pages: 1 Online-Ressource (200 p.)
    Keywords: Pharmacology
    Abstract: In the last decade, pharmacoepidemiology has emerged as an important field to study the use/effects of drugs in large populations in real life, allowing for improved benefits and effectiveness of drugs as well as a decline in drug-related risks. The correct assessment, reporting, monitoring, and prevention of adverse events in drugs' development, as well as therapy and post-market surveillance, is essential to improve clinical therapies and health outcomes. This book provides a comprehensive and unique overview of the relevance, new insights, and recent findings of pharmacoepidemiology and drug safety in public health
    Note: English
    URL: kostenfrei
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    MPI Ethno. Forsch.
  • 2
    Online Resource
    Online Resource
    Medical Toxicology (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838802783 , 9781838802776 , 9781839691553
    Language: English
    Pages: 1 Online-Ressource (348 p.)
    Keywords: Pharmacology
    Abstract: Medical toxicology is a sub-branch of toxicology concerned with the diagnosis, management, and prevention of poisoning and other adverse effects of drugs, cosmetics, personal care products, occupational and environmental toxicants, and biological agents. Poisoning with drugs, herbs, venoms, and toxins is a significant global public health problem. Medical toxicologists are involved in the assessment and treatment of acute or chronic poisoning, substance abuse, adverse drug reactions, drug overdoses, envenomation, industrial accidents, and other chemical exposures. As such, there is a pressing need for safe and specific antidotes, as many antidotes currently in use have a relatively low margin of safety or therapeutic index. This book focuses on poisonings with drugs, venoms, toxins, interaction in clinics, antidotes, and forensics. It provides qualified scientific knowledge on different aspects of medical toxicology, drug and substance abuse, clinical interactions between drugs and herbs, antidotes, antidote networks, and forensic toxicology
    Note: English
    URL: kostenfrei
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  • 3
    Online Resource
    Online Resource
    Antimicrobial Resistance : A One Health Perspective (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839624339 , 9781839624322 , 9781839624346
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Pharmacology
    Abstract: Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us
    Note: English
    URL: kostenfrei
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  • 4
    Online Resource
    Online Resource
    Corticosteroids : A Paradigmatic Drug Class (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839694820 , 9781839694813 , 9781839694837
    Language: English
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Pharmacology
    Abstract: Corticosteroids have a broad spectrum of mechanisms making them useful for treating a variety of pathological entities. They are crucial drugs in clinical control in a plethora of patients, despite recent advances resulting from the availability of new molecules with great selectivity for different receptors, cells, or biological mediators. This book includes high-quality scientific reviews of corticosteroids and their numerous uses
    Note: English
    URL: kostenfrei
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  • 5
    Online Resource
    Online Resource
    Aflatoxin B1 Occurrence, Detection and Toxicological Effects (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838802561 , 9781838802554 , 9781838801830
    Language: English
    Pages: 1 Online-Ressource (220 p.)
    Series Statement: Biochemistry 14
    Keywords: Pharmacology
    Abstract: This book consists of 11 chapters, divided into four parts. The chapters are written by experts in the field of aflatoxins. Select topics are presented here to provide a snapshot of current understanding of the occurrence and metabolism of aflatoxin B1, the contamination, exposure, and detection of aflatoxin B1, and the toxicological effects and detoxification of aflatoxin. The book is intended for students and scientists working in the field of aflatoxins
    Note: English
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  • 6
    Online Resource
    Online Resource
    Colloid Science in Pharmaceutical Nanotechnology (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789855968 , 9781789855951 , 9781838804985
    Language: English
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Pharmacology
    Abstract: This book presents studies on colloidal particle/nanoparticle systems and their applications. Some of the topics covered are include nanoparticle-based drug design, theranostic nanoparticles for cancer therapy, market perspectives of colloidal particles, and stability of nanoparticles. The authors focus on recent findings, applications, and new technological developments of the fundamental properties of colloidal particle systems
    Note: English
    URL: kostenfrei
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  • 7
    Online Resource
    Online Resource
    Drug Repurposing : Hypothesis, Molecular Aspects and Therapeutic Applications (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839685217 , 9781839685200 , 9781839685224
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Pharmacology
    Abstract: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry
    Note: English
    URL: kostenfrei
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  • 8
    Online Resource
    Online Resource
    Drug Discovery and Development : New Advances (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239768 , 9781789239751 , 9781789852196
    Language: English
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Pharmacology
    Abstract: The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process
    Note: English
    URL: kostenfrei
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  • 9
    Online Resource
    Online Resource
    Essential Oils : Oils of Nature (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789846416 , 9781789846409 , 9781838808518
    Language: English
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Pharmacology
    Abstract: Essential oils were used globally as a folk medicine for the treatment of a number of diseases because of the high content of natural compounds. Therefore, this book looks at research topics dealing with isolation, purification, and identification of active ingredients of essential oils from plants. This knowledge will provide significant information about essential oils to researchers and others interested in the field
    Note: English
    URL: kostenfrei
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  • 10
    Online Resource
    Online Resource
    Behavioral Pharmacology : From Basic to Clinical Research (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789856804 , 9781789856798 , 9781838805746
    Language: English
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Pharmacology
    Abstract: Behavioral pharmacology studies the biological bases of behavior and the pharmacological effects of natural or synthetic drugs through behavioral analysis, with the identification of substances that could contribute to improvement of the quality of life for humans. Through behavioral pharmacology, it is possible to generate knowledge about pharmacological bases that influence the normal or altered behavior from a multidisciplinary point of view, and which includes diverse areas of science. The purpose of this book “Behavioral Pharmacology- From Basic to Clinical Research” is to show some of the advances in the identification of pharmacological properties of natural and synthetic molecules that may be used in the development of pharmacological therapies destined for the treatment of illness and disorders that affect the wellness of humans
    Note: English
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  • 11
    Online Resource
    Online Resource
    Opioids : From Analgesic Use to Addiction (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838809539 , 9781838809584 , 9781838809546
    Language: English
    Pages: 1 Online-Ressource (106 p.)
    Keywords: Pharmacology
    Abstract: Morphine and other opioids are potent analgesic drugs, but their use can lead to complications. Being familiar with the use of this kind of drug can make the difference between obtaining the expected benefit of applied therapy or magnifying the risks to intolerable levels for the patient. Therefore, it is essential for practitioners to achieve adequate training in the management of these drugs based on criteria endorsed by scientific evidence that allows the proper use of these drugs and guarantees the best professional practice every time. Written by expert authors in the field, the purpose of this book is to offer an overview of opioid drugs, from their therapeutic use to the consequences associated
    Note: English
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  • 12
    Online Resource
    Online Resource
    Herbs and Spices (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839629365 , 9781839629358 , 9781839629372
    Language: English
    Pages: 1 Online-Ressource (112 p.)
    Keywords: Pharmacology
    Abstract: This edited volume, “Herbs and Spices”, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of agricultural and biological sciences. The book comprises single chapters authored by various researchers and edited by an expert active in the medical research area. All chapters are complete in itself but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on herbs and spices, and opening new possible research paths for further novel developments
    Note: English
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  • 13
    Online Resource
    Online Resource
    Anticoagulation Drugs : the Current State of the Art (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789850765 , 9781789850758 , 9781838801458
    Language: English
    Pages: 1 Online-Ressource (104 p.)
    Keywords: Pharmacology
    Abstract: In this book, you'll find the latest updates about the current use of anticoagulants in medical practice. This includes clinical pharmacotherapy, laboratory monitoring, and antidotes. You'll also find a special focus on heparin-induced thrombocytopenia, including various mechanisms and presentations. Finally, you'll find important details that will help you to understand what patients receiving anticoagulants know about these drugs and how to improve their quality of life
    Note: English
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  • 14
    Online Resource
    Online Resource
    Molecular Pharmacology (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839629327 , 9781839629310 , 9781839629334
    Language: English
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Pharmacology
    Abstract: This book concentrates on recent developments related to the application of original structural biology, biochemistry, biophysics, physiology, genetics, and molecular biology as well as basic pharmacological problems that offer mechanistic insights that are generally significant for the field of pharmacology. Written by experts, chapters cover such topics as drug transport mechanisms and drug–receptor complexes. This volume offers up-to-date, expert reviews of the fast-moving field of molecular pharmacology
    Note: English
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  • 15
    Online Resource
    Online Resource
    Receptors P1 and P2 as Targets for Drug Therapy in Humans (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789845358 , 9781789845341 , 9781838800789
    Language: English
    Pages: 1 Online-Ressource (110 p.)
    Keywords: Pharmacology
    Abstract: This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation
    Note: English
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  • 16
    Online Resource
    Online Resource
    Role of Novel Drug Delivery Vehicles in Nanobiomedicine (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239867 , 9781789239850 , 9781789843309
    Language: English
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Pharmacology
    Abstract: Medical Nanotechnology and Nanomedicine introduces non-experts to the world of nanomedicine and its evolving organizational infrastructure. Considering the fluid nature of nano breakthroughs and the delicate balance between benefits and consequences as they apply to medicine, readers at all levels will gain a practical, understandable base of information on these developments so that they may take the greatest advantage of them. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects and provides an ideal foundation upon which to plan and make decisions
    Note: English
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  • 17
    Online Resource
    Online Resource
    Biochemical Toxicology : Heavy Metals and Nanomaterials (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789846973 , 9781789846966 , 9781838809218
    Language: English
    Pages: 1 Online-Ressource (230 p.)
    Keywords: Pharmacology
    Abstract: Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health
    Note: English
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  • 18
    Online Resource
    Online Resource
    Metformin (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838804282 , 9781838804275 , 9781838807603
    Language: English
    Pages: 1 Online-Ressource (242 p.)
    Keywords: Pharmacology
    Abstract: The book “Metformin” aims to bring to light new concepts and trends related to the many metformin therapeutic features. After a history of over 60 years, with moments of decline and spectacular returns, metformin can now be regarded as a universal panacea, the valences of its therapeutics being increasingly appreciated, both in the background treatment of diabetes and pre-diabetes, but also in reproductive pathology, cancer, cardiovascular disease, and antiageing. In this respect, the mechanisms of action and the pharmacodynamics of metformin seem to be incompletely known, a number of current studies have revealed new action valences
    Note: English
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  • 19
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    Zebrafish in Biomedical Research (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789859867 , 9781789859850 , 9781789855739
    Language: English
    Pages: 1 Online-Ressource (80 p.)
    Keywords: Pharmacology
    Abstract: The zebrafish (Danio rerio) is one of the best animal models to understand biological mechanisms and develop new methods for treating some human diseases. In this framework, the zebrafish is a versatile animal model organism for many research fields because of its many advantages, including rapid embriyonic development, easy maintenance and transparency of its embryos. Zebrafish in Biomedical Research describes the current understanding of zebrafish as a model organism in biomedical science. Written by experts in the field, this volume discusses the potential use of zebrafish in neurological diseases such as Alzheimer's and Parkinson's, in respiratory and kidney diseases, and in developing new drugs
    Note: English
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  • 20
    Online Resource
    Online Resource
    Pharmaceutical Formulation Design : Recent Practices (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789858396 , 9781789856620 , 9781789858402
    Language: English
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Pharmacology
    Abstract: Pharmaceutical formulations have evolved from simple and traditional systems to more modern and complex novel dosage forms. Formulation development is a tedious process and requires an enormous amount of effort from many different people. Developing a stable novel dosage form and further targeting it to the desired site inside the body has always been a challenge. The purpose of this book is to bring together scholarly articles that highlight recent developments and trends in pharmaceutical formulation science. Each article has been written by authors specializing in the subject area and hailing from top institutions around the world. The book has been written in a systematic and lucid style explaining all basic concepts and fundamentals in a very simple way. This book aims to serve the need of all individuals involved at any level in the pharmaceutical dosage form development. I sincerely hope that the book will be liked by inquisitive students and learned colleagues
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  • 21
    Online Resource
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    Alkaloids : Their Importance in Nature and Human Life (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789845778 , 9781789845761 , 9781789846928
    Language: English
    Pages: 1 Online-Ressource (100 p.)
    Keywords: Pharmacology
    Abstract: "Alkaloids" is intended for by chemistry, biochemistry, pharmacy, and other medical students, biologists, chemists, biochemists, and other professionals involved in the field of alkaloids. All chapters in this book are written by professionals in the areas of alkaloid chemistry, biology, pharmacy, and other interesting applications. The chapters cover interesting and less obvious information about different groups of alkaloids
    Note: English
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  • 22
    Online Resource
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    Molecular Docking and Molecular Dynamics (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789840926 , 9781789840919 , 9781789852622
    Language: English
    Pages: 1 Online-Ressource (100 p.)
    Keywords: Pharmacology
    Abstract: This book clearly explains the principles of in silico tools of molecular docking and molecular dynamics. It provides examples of algorithms and procedures proposed by different software programs for visualizing and identifying potential interactions in complexes of biochemical interest. The book is structured in six chapters, each of which discusses different molecular simulation methodologies and provides concrete examples of complexes interactions. In each chapter authors give an overview of the treated subject, a description of the methodologies used, and a discussion of the results. The authors describe computational ways to achieve a rational design of bioactive compounds with various therapeutic applications, including antitumoral agents, antitubercular drugs, nonsteroidal anti-inflammatory drugs, and radiopharmaceuticals
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  • 23
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    Antioxidants (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239201 , 9781789239195 , 9781839627255
    Language: English
    Pages: 1 Online-Ressource (418 p.)
    Series Statement: Physiology 5
    Keywords: Pharmacology
    Abstract: Antioxidants are substances that can prevent or slow damage to living cells caused by free radicals, which are unstable molecules the body produces as a reaction to environmental and other pressures. Sometimes called “free-radical scavengers,” free radicals can cause mutation in different biological compounds such as protein, nucleic acids, and lipids, which lead to various diseases (cancer, cardiovascular disease, aging, etc.). Healthy foods are considered a main source of antioxidant compounds and from the beginning of a person’s life, a strong relationship is seen between antioxidant compounds and the prevention of certain diseases, such as types of inflammations, cardiovascular diseases, and different kinds of cancers. It is thus of great importance that new data relating to antioxidants and their biological activity be collected and that antioxidant modes of action be illustrated.Experts from around the world contributed to the current book, discussing antioxidant sources, modes of action, and their relation to human diseases. Twenty-five chapters are presented in two sections: Antioxidants: Sources and Modes of Action and Antioxidants Compounds and Diseases
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  • 24
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    Antidepressants : Preclinical, Clinical and Translational Aspects (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789852776 , 9781789852660 , 9781789852783
    Language: English
    Pages: 1 Online-Ressource (124 p.)
    Keywords: Pharmacology
    Abstract: Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications
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  • 25
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    Serotonin (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789852363 , 9781789852356 , 9781839620263
    Language: English
    Pages: 1 Online-Ressource (74 p.)
    Keywords: Pharmacology
    Abstract: My scientific journey brought me from Lanzhou in China, Leuven in Belgium, Bethesda in the USA, all the way to San Diego. Sometimes I pick up an assortment of scattered seashells while walking along the beautiful Torrey Pines Beach in San Diego. Likewise, this book contains an assortment of discussions of different aspects of serotonin to enrich our knowledge and understanding of this neurochemical. The book contains four different chapters: 1. Introductory chapter: From Measuring Serotonin Neurotransmission to Evaluating Serotonin Post-Receptor Signaling Transduction; 2. Serotonin Reuptake Inhibitors and Their Role in Chronic Pain Management; 3. Serotonin and Emotional Decision-Making; and 4. Clinical Aspects Related to Plasma Serotonin in the Horse
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  • 26
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    Seaweed Biomaterials (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789848472 , 9781789848465 , 9781838815479
    Language: English
    Pages: 1 Online-Ressource (74 p.)
    Keywords: Pharmacology
    Abstract: Seaweeds are the rich sources of naturally occurring valuable therapeutic substances. Many different marine organisms have been explored for novel bioactive compounds that exhibit antiviral, antitumor, anticoagulant, antidiabetic, antimicrobial, and antiinflammatory activities. Nonetheless, seaweed-derived polysaccharides have also been studied for the design of different kinds of novel drug delivery systems. Over the last 30-40 years, research has been ongoing in the search for novel seaweed-derived bioactive compounds. This book covers up-to-date information on seaweed biomaterials and their therapeutic potentials
    Note: English
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  • 27
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    Anticoagulation Therapy (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535126676 , 9789535126669 , 9789535173090
    Language: English
    Pages: 1 Online-Ressource (150 p.)
    Keywords: Pharmacology
    Abstract: The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists
    Note: English
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  • 28
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    Concepts, Compounds and the Alternatives of Antibacterials (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535122326 , 9789535154174
    Language: English
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Pharmacology
    Abstract: This edition is intended to provide better understanding of antibacterial drugs and their mechanism, the role of a few metal drug complexes as antibacterials, cross-checking of a few compounds and biomaterials against drug-resistant bacterial strains as well as a few alternative approaches using medicinal plant based formulations in the control of antibiotic-resistant bacteria. The information in this book provides clues for upcoming trends in treating antibiotic resistance problems with which one can explore new approaches in the treatment of common infections with drug-resistant strains
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    Complementary Therapies for the Body, Mind and Soul (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535121589 , 9789535172505
    Language: English
    Pages: 1 Online-Ressource (296 p.)
    Keywords: Pharmacology
    Abstract: Complementary Therapies (CT) refers to the practices, products, or health systems that are outside the realm of conventional medicine, used to treat disease or to promote health and well-being. Defining CT is difficult, because the field is very broad and constantly changing. The title of this book includes the words body, mind, and soul. The body and the mind (and their reciprocal relations) have been extensively studied scientifically. What about the soul? The book brings some points about this new ground in CT. We hope you find in the present work the sincere desire to collaborate with the dissemination of knowledge. May this book be useful and pleasant to you
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    Evidence-based Strategies in Herbal Medicine, Psychiatric Disorders and Emergency Medicine (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535117353 , 9789535172284
    Language: English
    Pages: 1 Online-Ressource (108 p.)
    Keywords: Pharmacology
    Abstract: This book intends to strike a balance between developments in pharmacotherapy research and the facts that researchers must absorb, as well as link scientific advances with clinical practice so that the management of diseases can be based on sound physiological concepts. Each chapter has been reviewed and new authors have brought up-to-date research to make the book more informative, illustrative, and easy to read. The book focuses on three major areas: Experimental, preclinical, and clinical applications of herbal medicine; Evidence-based strategies in emergency medicine and New approach in management of psychiatric disorders. The first three chapters describe new and modern applications of common herbs for treatment of several inflammatory and skin disorders, e.g. ulcerative colitis, bronchial asthma, osteoarthritis, multiple sclerosis, and melasma. Chapter four deals with the most severe hypertensive states that pose an immediate threat to life, and how to manage these situations. The fifth chapter is dedicated to tackling polypharmacy psychiatric disorders. We hope this book is useful to a wide range of readers, from students first learning about pharmacotherapy, through advanced clinicians and researchers who are looking for a review of current treatments and conceptualizations of the condition. It is our hope that this book may motivate readers to approach the evidence on pharmacotherapy with an open mind, and thereby spark an interest in initiating further contributions to the current scientific debate and treatment development efforts
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    Basic Pharmacokinetic Concepts and Some Clinical Applications (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535121978 , 9789535172659
    Language: English
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Pharmacology
    Abstract: This book considers the basic principles of biopharmaceutics and pharmacokinetics. It also illustrates clinical pharmacokinetic applications, such as recirculatory models, common antimalarial drugs, and clinical pharmacokinetic principles in critically ill patients, which are essential for medical professionals. Undergraduate and postgraduate students can make use of the information presented. The contents of the book represent the authors points of view as well as clinical findings and basic concepts of pharmacokinetics and biopharmaceutics that are covered in textbooks
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  • 32
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    Antimicrobial Resistance : An Open Challenge (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535122227 , 9789535154150
    Language: English
    Pages: 1 Online-Ressource (140 p.)
    Keywords: Pharmacology
    Abstract: Antibiotic resistance has become a worldwide health issue, globally recognized as the first priority by WHO. Many forms of resistance can spread with remarkable speed and cross international boundaries. World health leaders are devoting efforts to the problem by planning strategies for monitoring the effectiveness of public health interventions and detecting new trends and threats. This volume focuses on the problem from different perspectives, taking into consideration geographical dissemination (soil and water), human medicine (methicillin-resistant Staphylococcus aureus and Klebsiella pneumoniae) and veterinary (Enterococcus spp.) impact and molecular analysis. The purpose of this volume is to provide a useful tool for control and prevention and to discuss useful epidemiological data concerning ways of obtaining an accurate picture of resistance in different communities
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  • 33
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    Pesticides : Toxic Aspects (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535112174 , 9789535153894
    Language: English
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Pharmacology
    Abstract: The edited book Pesticides - Toxic Aspects contains an overview of attractive researchers of pesticide toxicology that covers the hazardous effects of common chemical pesticide agents employed every day in our agricultural practices. The combination of experimental and theoretical pesticide investigations of current interest will make this book of significance to researchers, scientists, engineers, and graduate students who make use of those different investigations to understand the toxic aspects of pesticides. We hope that this book will continue to meet the expectations and needs of all interested in different aspects of pesticide toxicity
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  • 34
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    Pharmacology and Therapeutics (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535116202 , 9789535172147
    Language: English
    Pages: 1 Online-Ressource (358 p.)
    Keywords: Pharmacology
    Abstract: The book "Pharmacology and Therapeutics" targets every aspect of the mechanisms for the chemical actions of both traditional and novel drugs. This book covers six sections: Molecular Modeling and Bio-molecular Pharmacology, Immunopharmacology, Environmental Pharmacology and Toxicology, Nanotechnology and Chemotherapy, Drugs and Drug Delivery System and Addiction Pharmacology. Each of these sections is interwoven with the theoretical aspects and experimental techniques of physiology, biochemistry, nutrition, cellular and molecular biology, microbiology, immunology, genetics, and pathology. This book will be a significant source to scientists, physicians, health care professionals and students who are interested to explore the effect of chemical agents on human life
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  • 35
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    Drug Discovery (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109068 , 9789535170662
    Language: English
    Pages: 1 Online-Ressource (526 p.)
    Keywords: Pharmacology
    Abstract: Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. Plant derived secondary metabolites have been used by humans to treat acute infections, health disorders and chronic illness for tens of thousands of years. Only during the last 100 years have natural products been largely replaced by synthetic drugs. Estimates of 200 000 natural products in plant species have been revised upward as mass spectrometry techniques have developed. For developing countries the identification and use of endogenous medicinal plants as cures against cancers has become attractive. Books on drug discovery will play vital role in the new era of disease treatment using natural products
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  • 36
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    Mycotoxin and Food Safety in Developing Countries (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535110965 , 9789535171287
    Language: English
    Pages: 1 Online-Ressource (282 p.)
    Keywords: Pharmacology
    Abstract: This book provides information on the incidence of fungi and mycotoxins in some African countries, the health implications and possible intervention control strategies for mycotoxins in developing countries and in Africa in particular. It will therefore be of interest to students, educators, researchers and policy makers in the fields of medicine, agriculture, food science and technology, trade and economics. Food regulatory officers also have quite a lot to learn from the book. Although a lot of the generated data in the area of mycotoxicology are available to the developed world, information on the subject area from Africa is scanty and not usually available in a comprehensive form. This book attempts to address the gap. Being an open access book, it will be of great benefit to scientists in developing countries who have limited access to information due to lack of funds to pay or subscribe for high quality journals and data from commercial publishing and database companies
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  • 37
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    An Integrated View of the Molecular Recognition and Toxinology : From Analytical Procedures to Biomedical Applications (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111511 , 9789535153825
    Language: English
    Pages: 1 Online-Ressource (546 p.)
    Keywords: Pharmacology
    Abstract: Molecular Toxinology has been consolidated as a scientific area focused on the intertwined description of several aspects of animal toxins. In an inquiring biotechnological world, animal toxins appear as an invaluable source for the discovery of therapeutic polypeptides. Animal toxins rely on specific chemical interactions with their partner molecule to exert their biological actions. The comprehension of how molecules interact and recognize their target is essential for the rational exploration of bioactive polypeptides as therapeutics. Investigation on the mechanism of molecular interaction and recognition offers a window of opportunity for the pharmaceutical industry and clinical medicine. Thus, this book brings examples of two interconnected themes - molecular recognition and toxinology concerning to the integration between analytical procedures and biomedical applications
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  • 38
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    Tandem Mass Spectrometry : Molecular Characterization (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111368 , 9789535150381
    Language: English
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Pharmacology
    Abstract: Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem Mass Spectrometry serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences
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  • 39
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    Effects of Antidepressants (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535106630 , 9789535170136
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Pharmacology
    Abstract: Over the last fifty years, many studies of psychiatric medication have been carried out on the basis of psychopharmacology. At the beginning, researchers and clinicians found the unexpected effectiveness of some medications with therapeutic effects in anti-mood without knowing the reason. Next, researchers and clinicians started to explore the mechanism of neurotransmitters and started to gain an understanding of how mental illness can be. Antidepressants are one of the most investigated medications. Having greater knowledge of psychopharmacology could help us to gain more understanding of treatments. In total ten chapters on various aspects of antidepressants were integrated into this book to help beginners interested in this field to understand depression
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  • 40
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    Drug Discovery : Research in Pharmacognosy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102137 , 9789535168683
    Language: English
    Pages: 1 Online-Ressource (256 p.)
    Keywords: Pharmacology
    Abstract: This book, Drug Discovery Research in Pharmacognosy provides a full picture of research in the area of pharmacognosy with the goal of drug discovery from natural products based on the traditional knowledge or practices. Several plants that have been used as food show their potential as chemopreventive agents and the claims of many medicinal plants used in traditional medicine are now supported by scientific studies. Drug Discovery Research in Pharmacognosy is a promising road map which will help us find medicine for all!
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  • 41
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    Antiviral Drugs : Aspects of Clinical Use and Recent Advances (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535102564 , 9789535168850
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Pharmacology
    Abstract: The articles that appear in Antiviral Drugs - Aspects of Clinical Use and Recent Advances cover several topics that reflect the varied mechanisms of viral disease pathogenesis and treatment. Clinical management and new developments in the treatment of virus-related diseases are the two main sections of the book. The first part reviews the treatment of hepatitis C virus infection, the management of virus-related acute retinal necrosis, the use of leflunomide therapy in renal transplant patients, and mathematical modeling of HIV-1 treatment responses. Basic research topics are dealt with in the second half of the book. New developments in the treatment of the influenza virus, the use of animal models for HIV-1 drug development, the use of single chain camelid antibodies against negative strand RNA viruses, countering norovirus infection, and the use of plant extracts to treat herpes simplex virus infection are described. The content of the book is not intended to be comprehensive, but aims to provide the reader with insights into selected aspects of established and new viral therapies
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    Essential Notes in Psychiatry (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105749 , 9789535169864
    Language: English
    Pages: 1 Online-Ressource (596 p.)
    Keywords: Pharmacology
    Abstract: Psychiatry is one of the major specialties of medicine, and is concerned with the study and treatment of mental disorders. In recent times the field is growing with the discovery of effective therapies and interventions that alleviate suffering in people with mental disorders. This book of psychiatry is concise and clearly written so that it is usable for doctors in training, students and clinicians dealing with psychiatric illness in everyday practice. The book is a primer for those beginning to learn about emotional disorders and psychosocial consequences of severe physical and psychological trauma; and violence. Emphasis is placed on effective therapies and interventions for selected conditions such as dementia and suicide among others and the consequences of stress in the workplace. The book also highlights important causes of mental disorders in children
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  • 43
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    Clinical Use of Local Anesthetics (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104308 , 9789535169420
    Language: English
    Pages: 1 Online-Ressource (112 p.)
    Keywords: Pharmacology
    Abstract: Local anesthetics are being increasingly applied in different surgeries. Lower side effects of neuroaxial anesthesia, regional anesthesia, and field block, in comparison to general anesthesia (volatile and intravenous agents), are the main reasons why physicians prefer to conduct surgeries under local anesthesia, especially in outpatient and day care surgeries. It is important to emphasize the presence of an anesthesiologist, and vigilant monitoring of the homodynamic parameters, in decreasing a patient's anxiety, exerting other modalities for analgesia and increasing the safety margin in many procedures
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    Pharmacology (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102229 , 9789535168706
    Language: English
    Pages: 1 Online-Ressource (734 p.)
    Keywords: Pharmacology
    Abstract: The history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology
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  • 45
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    Pharmacotherapy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105329 , 9789535169727
    Language: English
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Pharmacology
    Abstract: The intent of this book is to provide an overview of current conceptualizations of Pharmacotherapy. The book focuses on three major areas; diagnosis, treatment, and prevention for a wide array of diseases; Cognitive and Psychological disorders (Schizophrenia and Nicotine addiction), Inflammatory disorders (New Chemical anti-inflammatory and Immunotherapy), updated antihypertensive therapy and healing of ulcers with venous origin. A separate chapter is dedicated to the rationality of drug use in earthquake injuries. The last chapter deals with Imaging of potential therapeutic or diagnostic agents in animal models in the early stage of research. We hope this book is useful to a wide range of people, from students first learning about Pharmacotherapy, to advanced clinicians and researchers
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    Medicinal Chemistry and Drug Design (2012)
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    ISBN: 9789535105138 , 9789535169659
    Language: English
    Pages: 1 Online-Ressource (420 p.)
    Keywords: Pharmacology
    Abstract: Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecules processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitors, molecular aspects of drug metabolism, organic synthesis, prodrug synthesis, in silico studies and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in medicinal chemistry and drug design. Particular emphasis is devoted to both theoretical and experimental aspect of modern drug design. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in chemistry, protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medicinal approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of medicinal chemistry and drug design
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    Antihypertensive Drugs (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104629 , 9789535169499
    Language: English
    Pages: 1 Online-Ressource (162 p.)
    Keywords: Pharmacology
    Abstract: Hypertension, known as a "silent killer" is widely prevalent and a major risk factor for cardiovascular diseases. It afflicts more than one billion population worldwide and is a leading cause of morbidity and mortality. The authors of the chapters look from different angles to hypertension, sharing their new knowledge and experience in the direction of deep understanding and more clarification of the disease providing an invaluable resource not only for clinicians, but also for all medical sciences students and health providers
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    Bioactive Compounds in Phytomedicine (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078052 , 9789535166320
    Language: English
    Pages: 1 Online-Ressource (230 p.)
    Keywords: Pharmacology
    Abstract: There are significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children. Herbal therapy is less expensive, more readily available, and increasingly becoming common practice all over the world. Such practices have both their benefits and risks. However, herbal self-therapy might have serious health consequences due to incorrect self-diagnosis, inappropriate choice of herbal remedy or adulterated herbal product. In addition, absence of clinical trials and other traditional safety mechanisms before medicines are introduced to the wider market results in questionable safe dosage ranges which may produce adverse and unexpected outcomes. Therefore, the use of herbal remedies requires sufficient knowledge about the efficacy, safety and proper use of such products. Hence, it is necessary to have baseline data regarding the use of herbal remedies and to educate future health professionals about various aspects of herbal remedies
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    Readings in Advanced Pharmacokinetics : Theory, Methods and Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105336 , 9789535169734
    Language: English
    Pages: 1 Online-Ressource (390 p.)
    Keywords: Pharmacology
    Abstract: This book, “Readings in Advanced Pharmacokinetics - Theory, Methods and Applications”, covers up to date information and practical topics related to the study of drug pharmacokinetics in humans and in animals. The book is designed to offer scientists, clinicians and researchers a choice to logically build their knowledge in pharmacokinetics from basic concepts to advanced applications. This book is organized into two sections. The first section discusses advanced theories that include a wide range of topics; from bioequivalence studies, pharmacogenomics in relation to pharmacokinetics, computer based simulation concepts to drug interactions of herbal medicines and veterinary pharmacokinetics. The second section advances theory to practice offering several examples of methods and applications in advanced pharmacokinetics
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  • 50
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    Psychology : Selected Papers (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105879 , 9789535151265
    Language: English
    Pages: 1 Online-Ressource (344 p.)
    Keywords: Pharmacology
    Abstract: This book represents a selection of chapters that address several topics from the broad domains of psychology: alcoholism, clinical interventions, treatment of depression, personality psychology, qualitative research methods in psychology, and social psychology. As such we have interesting blend of studies from experts from a diverse array of psychology fields. The selected chapters will take the reader on an exciting journey in the domains of psychology. We are sure the content will appeal to a great audience
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    Bioterrorism (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102052 , 9789535168676
    Language: English
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Pharmacology
    Abstract: This book consists of nine chapters, written by international authorities, discussing various aspects of bioterrorism preparedness and response. Five of the chapters are agent-specific and highlight the pathogenesis, prevention and treatment, and the potential of specific organisms (Rickettsia and Yersinia pestis) or toxins (ricin, botulinum neurotoxins, and staphylococcal enterotoxins) to be used for nefarious purposes. Four chapters discuss different aspects of detecting and responding to a bioterrorism attack. These include methods for spatio-temporal disease surveillance, international laboratory response strategies, detection of botulinum neurotoxins in food and other matrices, and the use of physical methods (ie Raman spectroscopy) to detect spores
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    Virtual Screening (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103080 , 9789535169048
    Language: English
    Pages: 1 Online-Ressource (110 p.)
    Keywords: Pharmacology
    Abstract: Pharmacophore modeling, QSAR analysis, CoMFA, CoMSIA, docking and molecular dynamics simulations, are currently implemented to varying degrees in virtual screening towards discovery of new bioactive hits. Implementation of such techniques requires multidisciplinary knowledge and experience. This volume discusses established methodologies as well as new trends in virtual screening with aim of facilitating their use in drug discovery
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    Clinical Applications of Pharmacogenetics (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103899 , 9789535169284
    Language: English
    Pages: 1 Online-Ressource (306 p.)
    Keywords: Pharmacology
    Abstract: The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. This book presents Pharmacogenetic examples from a broad spectrum of different drugs, for different diseases, which are representative of different stages of evaluation or application. It has been designed so as to serve both the unfamiliar reader through explanations of basic Pharmacogenetic concepts, the clinician with presentation of the latest developments and international guidelines, and the research scientist with examples of Pharmacogenetic applications, discussions on the limitations and an outlook on the new scientific trends in this field
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    Ecotoxicology (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535100270 , 9789535168072
    Language: English
    Pages: 1 Online-Ressource (158 p.)
    Keywords: Pharmacology
    Abstract: This is a good book on upcoming areas of Ecotoxicology. The first chapter describes genotoxicity of heavy metals in plants. The second chapter offer views on chromatographic methodologies for the estimation of mycotoxin. Chapter three is on effects of xenobiotics on benthic assemblages in different habitats of Australia. Laboratory findings of genotoxins on small mammals are presented in chapter four. The fifth chapter describes bioindicators of soil quality and assessment of pesticides used in chemical seed treatments. European regulation REACH in marine ecotoxicology is described in chapter six. X-ray spectroscopic analysis for trace metal in invertebrates is presented in chapter seven. The last chapter is on alternative animal model for toxicity testing. In conclusion, this book is an excellent and well organized collection of up dated information on Ecotoxicology. The data presented in it might be a good starting point to develop research in the field of ECOTOXICOLOGY
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