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  • MPI Ethno. Forsch.  (125)
  • [Erscheinungsort nicht ermittelbar] : IntechOpen  (125)
  • Computer modelling & simulation  (66)
  • Proteins
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  • MPI Ethno. Forsch.  (125)
Material
Language
Years
Author, Corporation
Publisher
Keywords
  • 1
    Online Resource
    Online Resource
    Time Series Analysis : New Insights (2023)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781803563060 , 9781803563053 , 9781803563077
    Language: Undetermined
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Computer modelling & simulation
    Abstract: Time series data consist of a collection of observations obtained through repeated measurements over time. When the points are plotted on a graph, one of the axes is always time. Time series analysis is a specific way of analyzing a sequence of data points. Time series data are everywhere since time is a constituent of everything that is observable. As our world becomes increasingly digitized, sensors and systems are constantly emitting a relentless stream of time series data, which has numerous applications across various industries. The editors of this book are happy to provide the specialized reader community with this book as a modest contribution to this rapidly developing domain
    Note: English
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  • 2
    Online Resource
    Online Resource
    Simulation Modeling (2022)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839696848 , 9781839696831 , 9781839696855
    Language: Undetermined
    Pages: 1 Online-Ressource (266 p.)
    Keywords: Computer modelling & simulation
    Abstract: The book presents some recent specialized works of a theoretical and practical nature in the field of simulation modeling, which is being addressed to a large number of specialists, mathematicians, doctors, engineers, economists, professors, and students. The book comprises 11 chapters that promote modern mathematical algorithms and simulation modeling techniques, in practical applications, in the following thematic areas: mathematics, biomedicine, systems of systems, materials science and engineering, energy systems, and economics. This project presents scientific papers and applications that emphasize the capabilities of simulation modeling methods, helping readers to understand the phenomena that take place in the real world, the conditions of their development, and their effects, at a high scientific and technical level. The authors have published work examples and case studies that resulted from their researches in the field. The readers get new solutions and answers to questions related to the emerging applications of simulation modeling and their advantages
    Note: English
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  • 3
    Online Resource
    Online Resource
    Computational Statistics and Applications (2022)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839697838 , 9781839697821 , 9781839697845
    Language: Undetermined
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Computer modelling & simulation
    Abstract: Nature evolves mainly in a statistical way. Different strategies, formulas, and conformations are continuously confronted in the natural processes. Some of them are selected and then the evolution continues with a new loop of confrontation for the next generation of phenomena and living beings. Failings are corrected without a previous program or design. The new options generated by different statistical and random scenarios lead to solutions for surviving the present conditions. This is the general panorama for all scrutiny levels of the life cycles. Over three sections, this book examines different statistical questions and techniques in the context of machine learning and clustering methods, the frailty models used in survival analysis, and other studies of statistics applied to diverse problems
    Note: English
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  • 4
    Online Resource
    Online Resource
    Protein Detection (2022)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839693533 , 9781839693526 , 9781839693540
    Language: Undetermined
    Pages: 1 Online-Ressource (132 p.)
    Series Statement: Biochemistry 31
    Keywords: Proteins
    Abstract: The book explores distinct aspects of protein purification and characterization steps. It discusses solubility problems, resin selection tricks, and essential credentials in a purification process. In addition, the book examines aggregation and proteinopathy-related protein detection methods and reviews several essential protein detection and characterization methods in cancer for diagnosis, prognosis, and therapy, such as enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, flow cytometry, western blot, mass spectrometry, and others
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  • 5
    Online Resource
    Online Resource
    Advances in Principal Component Analysis (2022)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781803557663 , 9781803557656 , 9781803557670
    Language: Undetermined
    Pages: 1 Online-Ressource (252 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book describes and discusses the use of principal component analysis (PCA) for different types of problems in a variety of disciplines, including engineering, technology, economics, and more. It presents real-world case studies showing how PCA can be applied with other algorithms and methods to solve both large and small and static and dynamic problems. It also examines improvements made to PCA over the years
    Note: English
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  • 6
    Online Resource
    Online Resource
    Bayesian Inference : Recent Advantages (2022)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781803560458 , 9781803560441 , 9781803560465
    Language: Undetermined
    Pages: 1 Online-Ressource (126 p.)
    Keywords: Computer modelling & simulation
    Abstract: With growing interest in data mining and its merits, including the incorporation of historical or experiential information into statistical analysis, Bayesian inference has become an important tool for analyzing complicated data and solving inverse problems in various fields such as artificial intelligence. This book introduces recent developments in Bayesian inference, and covers a variety of topics including robust Bayesian estimation, solving inverse problems via Bayesian theories, hierarchical Bayesian inference, and its applications for scattering experiments. We hope that this book will stimulate more extensive research on Bayesian fronts to include theories, methods, computational algorithms and applications in various fields such as data science, AI, machine learning, and causality analysis
    Note: English
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  • 7
    Online Resource
    Online Resource
    Recent Advances in Numerical Simulations (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839681691 , 9781839681684 , 9781839693151
    Language: Undetermined
    Pages: 1 Online-Ressource (290 p.)
    Keywords: Computer modelling & simulation
    Abstract: A numerical simulation is a computing calculation following a program that develops a mathematical model for a physical, social, economic, or biological system. Numerical simulations are required for analyzing and studying the behavior of systems whose mathematical models are very complex, as in the case of nonlinear systems. Capturing the resulting uncertainty of models based on uncertain parameters and constraints in confidence intervals (1-D), or more generally (〉1-D) confidence regions, is very common for expressing to which degree the computed result is believed to be consistent with possible values of the targeted observable. This book examines the different methods used in numerical simulations, including adaptive and stochastic methods as well as finite element analysis research. This work is accompanied by studies of confidence regions, often utilized to express the credibility of such calculations and simulations
    Note: English
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  • 8
    Online Resource
    Online Resource
    Homology Molecular Modeling : Perspectives and Applications (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839628061 , 9781839628054 , 9781839628115
    Language: English
    Pages: 1 Online-Ressource (146 p.)
    Keywords: Proteins
    Abstract: Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology
    Note: English
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  • 9
    Online Resource
    Online Resource
    Methods in Molecular Medicine (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839627279 , 9781839627262 , 9781839627286
    Language: English
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Proteins
    Abstract: Treatment risk and response to therapy prediction can be forecasted through early diagnosis, which improves prognosis reliability and effectiveness of therapies. This book covers contemporary advances in molecular markers, disease-causing variants, retroelements, and the basis of distinct diseases
    Note: English
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  • 10
    Online Resource
    Online Resource
    Oxidoreductase (2021)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838809010 , 9781838809003 , 9781838809027
    Language: English
    Pages: 1 Online-Ressource (180 p.)
    Series Statement: Biochemistry 19
    Keywords: Proteins
    Abstract: Oxidoreductase enzymes are a group of enzymes that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. Oxidoreductase enzymes utilize NADP+ or NAD+ as cofactors. Oxidoreductase enzymes include the following: oxidase, dehydrogenase, peroxidase, hydroxylase, oxygenase, and reductase. Most oxidoreductase enzymes are dehydrogenases. However, reductases are also common. The accepted nomenclature for dehydrogenases is “donor dehydrogenase”, where the donor is the oxidized substrate. Metabolic abnormalities disorders resulting from a deficiency (quantitative and qualitative) or from over-activity of oxidoreductase, which may contribute to the decreased normal performance of life, are becoming common. This book covers the potential applications of oxidoreductases on the growth of oxidoreductase-based diagnostic tests and better biosensors in the design of inventive systems for crucial co-enzyme generations and in the synthesis of polymers and organic substrates. The book describes the role of oxidoreductase as essential in medical drug formation. It can be employed to produce a huge amount of compounds that act as medical mediators like Cephalosporin (beta lactam antibiotic). Furthermore, the idea of how to use different enzymes as targets for medical treatment in different types of cancers is also described in this book
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  • 11
    Online Resource
    Online Resource
    Extracellular Vesicles and Their Importance in Human Health (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789239447 , 9781789239430 , 9781789845839
    Language: English
    Pages: 1 Online-Ressource (170 p.)
    Keywords: Proteins
    Abstract: Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases
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  • 12
    Online Resource
    Online Resource
    Proteoforms : Concept and Applications in Medical Sciences (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838800345 , 9781838800338 , 9781839628320
    Language: English
    Pages: 1 Online-Ressource (90 p.)
    Keywords: Proteins
    Abstract: A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia
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  • 13
    Online Resource
    Online Resource
    Advances in Lipid Metabolism (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789844597 , 9781789844580 , 9781789851373
    Language: English
    Pages: 1 Online-Ressource (98 p.)
    Keywords: Proteins
    Abstract: This edited volume is a collection of reviewed and relevant research chapters concerning developments within the field of lipid metabolism. It includes scholarly contributions from experts in the field that cover such topics as roles of lipids in cancer, analytical tools for lipid assessment in biological assays, plant lipid metabolism, the effect of nanoparticles on lipid peroxidation in plants, and fatty acid compositions in fermented fish products. This book provides a thorough overview of the latest research efforts by international authors on lipid metabolism, and opens new possible research paths for further novel developments
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  • 14
    Online Resource
    Online Resource
    Update on Mesenchymal and Induced Pluripotent Stem Cells (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789238082 , 9781789238075 , 9781838805265
    Language: English
    Pages: 1 Online-Ressource (148 p.)
    Keywords: Proteins
    Abstract: This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells. The book is divided into three main sections that cover several topics including: sources of both stem cell types, their preparation and general properties, as well as their therapeutic indications and clinical utilization with particular attention given to their use in infectious diseases, osteoarthritis, as well as immunological disorders
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  • 15
    Online Resource
    Online Resource
    Biophysical Chemistry : Advance Applications (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789840483 , 9781789840476 , 9781838801380
    Language: English
    Pages: 1 Online-Ressource (110 p.)
    Series Statement: Physiology 7
    Keywords: Proteins
    Abstract: Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences
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  • 16
    Online Resource
    Online Resource
    Understanding the Molecular Crosstalk in Biological Processes (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789848939 , 9781789848922 , 9781838819651
    Language: English
    Pages: 1 Online-Ressource (90 p.)
    Keywords: Proteins
    Abstract: It is essential to address the aspects related to the crosstalk approach in understanding complex biological processes in different organisms, including plants, microorganisms, animals, and humans. This will definitely provide the information required to achieve the biological advancements. Therefore, this book highlights the advances made in the research field covering crosstalk in different biological processes. Current research trends, future research directions, and challenges are also addressed. This book will provoke the interest of various readers, researchers, and scientists who will find this information useful for the advancement of their research on biological processes in living organisms
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  • 17
    Online Resource
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    Computational Models in Engineering (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789238709 , 9781789238693 , 9781789854008
    Language: English
    Pages: 1 Online-Ressource (146 p.)
    Keywords: Computer modelling & simulation
    Abstract: The accurate prediction of multi-physical and multi-scale physical/chemical/mechanical processes in engineering remains a challenging problem despite considerable work in this area and the acceptance of finite element analysis and computational fluid dynamics as design tools. This book intends to provide the reader with an overview of the latest developments in computational techniques used in various engineering disciplines. The book includes leading-edge scientific contributions of computational and applied mathematics, computer science and engineering focusing on the modelling and simulation of complex engineering systems and multi-physical/multi-scale engineering problems. The following topics are covered: numerical analysis and algorithms, software development, coupled analysis, multi-criteria optimization as they applied to all kinds of applied and emerging problems in energy systems, additive manufacturing, propulsion systems, and thermal engineering
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  • 18
    Online Resource
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    Toll-like Receptors (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789853919 , 9781789845235 , 9781789853926
    Language: English
    Pages: 1 Online-Ressource (110 p.)
    Keywords: Proteins
    Abstract: Toll-like receptors (TLRs) are pattern recognition receptors that allow innate immunity to protect our body against invading pathogens. They are alsoregulators of adaptive immunity. The human TLR was discovered quite recently, but its functional significance is known worldwide and today TLR agonists have been approved for use in humans. This book provides an overview of TLRs and their role in parasitic infections and neurodegenerative diseases. It is hoped that it will encourage readers to seek out the latest developments in TLRs
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  • 19
    Online Resource
    Online Resource
    Programmed Cell Death (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789847499 , 9781789847482 , 9781839684708
    Language: English
    Pages: 1 Online-Ressource (152 p.)
    Keywords: Proteins
    Abstract: This book incorporates developments in our understanding of cell death mechanisms and highlights recent advances in programmed cell death regulation processes. It provides the reader with the network of pathways targeted by herbal anticancer drugs and discusses the role of endoplasmic reticulum stress in cell death mechanisms in addition to highlighting the mechanisms of autophagy and its role in diseases. This book provides valuable material for researchers and for teaching postgraduate students. Emphasis on recent advances and their clinical applications offers insights to researchers that will likely lead to the development of novel therapeutic approaches
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  • 20
    Online Resource
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    Free Radical Medicine and Biology (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789851441 , 9781789851434 , 9781839625954
    Language: English
    Pages: 1 Online-Ressource (130 p.)
    Series Statement: Physiology 10
    Keywords: Proteins
    Abstract: Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems
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  • 21
    Online Resource
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    Telomerase and non-Telomerase Mechanisms of Telomere Maintenance (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789845754 , 9781789845747 , 9781838802813
    Language: English
    Pages: 1 Online-Ressource (130 p.)
    Keywords: Proteins
    Abstract: This book, Telomerase and non-Telomerase Mechanisms of Telomere Maintenance, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of biochemistry, genetics, and molecular biology. The book comprises single chapters authored by various researchers and edited by an expert active in the molecular biology research area. All chapters are individually complete but united under a common research topic. This publication aims to provide a thorough overview of the latest research efforts by international authors on biochemistry, genetics,and molecular biology, and open new possible research paths for further novel developments. A note from the publisher: It is with great sadness and regret that we inform the contributing authors and readers of this book that the Editor, Dr Tammy A. Morrish, passed away during the publishing process of the book and before having a chance to see its publication. The book Telomerase and non-Telomerase Mechanisms of Telomere Maintenance was her first edited volume with us. Fruitful collaboration continued until her final days. We would like to acknowledge Dr Morrish's contribution to scientific publishing, which she made during years of dedicated work, and express our gratitude for her pleasant cooperation with us
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  • 22
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    Chemistry and Biological Activity of Steroids (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789855166 , 9781789855159 , 9781789856088
    Language: English
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Proteins
    Abstract: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed
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  • 23
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    Glutathione System and Oxidative Stress in Health and Disease (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781838801267 , 9781838801250 , 9781839680182
    Language: English
    Pages: 1 Online-Ressource (138 p.)
    Series Statement: Biochemistry 17
    Keywords: Proteins
    Abstract: The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system
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  • 24
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    Numerical Modeling and Computer Simulation (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781838811976 , 9781838811969 , 9781838811983
    Language: English
    Pages: 1 Online-Ressource (160 p.)
    Keywords: Computer modelling & simulation
    Abstract: Information technologies have changed people’s lives to a great extent, and now it is almost impossible to imagine any activity that does not depend on computers in some way. Since the invention of first computer systems, people have been trying to avail computers in order to solve complex problems in various areas. Traditional methods of calculation have been replaced by computer programs that have the ability to predict the behavior of structures under different loading conditions. There are eight chapters in this book that deal with: optimal control of thermal pollution emitted by power plants, finite difference solution of conjugate heat transfer in double pipe with trapezoidal fins, photovoltaic system integrated into the buildings, possibilities of modeling Petri nets and their extensions, etc
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  • 25
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    Ubiquitin : Proteasome Pathway (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781838808419 , 9781838804329 , 9781838808426
    Language: English
    Pages: 1 Online-Ressource (124 p.)
    Series Statement: Biochemistry 18
    Keywords: Proteins
    Abstract: The ubiquitin-proteasome pathway consists of ubiquitin, substrate proteins, E1 enzymes, E2 enzymes, E3 enzymes, and proteasome, which acts in a series of enzymatic reaction chains to ubiquitinate substrate proteins such as surplus and misfolded proteins for degradation by the proteasome to maintain the balance between protein synthesis and degradation in a cell and tissue. Moreover, deubiquitinating enzymes can remove the attached ubiquitin chain, which results in a reverse ubiquitination-deubiquitination process involved in multiple biological processes in a cell and tissue. The changes of components in the ubiquitin-proteasome pathway are associated with multiple pathophysiological processes, such as cancers and neurodegenerative diseases. This book presents the new advances in concepts, analytical methodology, and application of ubiquitin-proteasome pathway for clarification of molecular mechanisms and discovery of new therapeutic targets and drugs in different diseases
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  • 26
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    Cell Growth (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789845570 , 9781789238068 , 9781789853117
    Language: English
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Proteins
    Abstract: This book on cell growth is the ideal resource for a scientist who wishes to learn more about cell growth topics. It provides information on plant growth hormones, kinetic studies on cell growth, growth of fungal cells and production, cell growth measurement, ion homeostasis response to nutrient deficiency stress in plants, intracellular lipid homeostasis in eukaryotes, and cell-based assays in cancer research. Each topic begins with a summary of the essential facts. Chapters were carefully edited to maintain consistent use of terminology and approach of covering topics in a uniform, systematic format
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  • 27
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    Innovations in Cell Research and Therapy (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789844573 , 9781789844566 , 9781838800208
    Language: English
    Pages: 1 Online-Ressource (162 p.)
    Keywords: Proteins
    Abstract: All living things are comprised of cells. A cell is the building block of complex organisms. All cells contain genetic material. Some cells contain subunits known as organelles that perform specific functions. Protein processing, energy generation, and macromolecular biosynthesis are some of the functions of organelles. Recently, advances in cell biology have elucidated new insights in cellular development and the unique functions of different types of cells. The era of biotechnology is rooted in biologics, and cell biology has delivered novel therapeutic candidates. Personalized medicine has its underpinnings in cell biology. Innovations in Cell Research and Therapy focuses on recent key advances that are transforming health and medical sciences. Understanding fundamental cellular processes, including cellular differentiation, the many applications of stem cells, natural and synthetic approaches for inducing apoptosis, and new insights into organelle biology and macromolecular processing are representative examples of the topics that are addressed in the chapters found in this book
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    Lipid Peroxidation Research (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781839685484 , 9781839685477 , 9781839685491
    Language: English
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Proteins
    Abstract: Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases
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    Immunohistochemistry : The Ageless Biotechnology (2020)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781838808211 , 9781838808204 , 9781838808228
    Language: English
    Pages: 1 Online-Ressource (140 p.)
    Keywords: Proteins
    Abstract: Immunohistochemistry - The Ageless Biotechnology is a book that is ideal for undergraduate and graduate biomedical researchers, and medical and dental health professionals. It is a detailed text, which emphasizes the laboratory and clinical implications of immunohistochemistry. The text covers the advances of immunohistochemistry from its humble origins in the 1930s up to the new decade of 2020. The book also offers a review of the immunohistochemistry detection systems with emphasis on their principles, history, and their advantages. It also stipulates the limitations and delineates the factors that need to be considered for choosing an appropriate detection system for IHC applications. The book describes current laboratory techniques and new applications for the technology. As the reader will observe, the book provides new and useful information concerning the rapidly advancing field of immunohistochemistry
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    Modeling and Computer Simulation (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789857962 , 9781789857955 , 9781839621260
    Language: Undetermined
    Pages: 1 Online-Ressource (86 p.)
    Keywords: Computer modelling & simulation
    Abstract: Computer simulation or a computer model has the task of simulating the behaviour of an abstract model of a particular system. Computer simulations have become a useful part of mathematical modeling of many natural systems in physics, quantum mechanics, chemistry, biology, economic systems, psychology, and social sciences, as well as in the engineering process of new technologies. The authors of the five chapters have presented various applications of computer simulations as well as their advantages and disadvantages. They describe the process of modeling and its simulation of heat recovery steam generators, the chronometer detent escapement mechanism, relevant sociotechnical processes with regard to new housing and building law and regional management trends in the European Union, and the agent-based model for biological systems
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  • 31
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    Ubiquitin Proteasome System : Current Insights into Mechanism Cellular Regulation and Disease (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781838804916 , 9781838804909 , 9781838807177
    Language: Undetermined
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Proteins
    Abstract: The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways
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  • 32
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    Proteomics Technologies and Applications (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9781789846119 , 9781789846102 , 9781839622212
    Language: Undetermined
    Pages: 1 Online-Ressource (132 p.)
    Keywords: Proteins
    Abstract: Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses
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  • 33
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    Peptide Synthesis (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781839682582 , 9781839682575 , 9781839682599
    Language: English
    Pages: 1 Online-Ressource (118 p.)
    Keywords: Proteins
    Abstract: Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides
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    Simulation Modelling Practice and Theory (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789853643 , 9781789853636 , 9781839620362
    Language: English
    Pages: 1 Online-Ressource (82 p.)
    Keywords: Computer modelling & simulation
    Abstract: The influx of data in the world today needs analysis that no one method can handle. Some reports estimated the influx of data would reach 163 zitabytes by 2025, hence the need for simulation and modeling theory and practice. Simulation and modeling tools and techniques are most important in this day and age. While simulation carries the needed work, tools for visualizing the results help in the decision-making process. Simulation ranges from a simple queue to molecular dynamics, including seismic reliability analysis, structural integrity assessment, games, reliability engineering, and system safety. This book will introduce practitioners, researchers, and novice users to simulation and modeling, and to the world of imagination
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    Liposomes : Advances and Perspectives (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789844955 , 9781789844948 , 9781838812324
    Language: English
    Pages: 1 Online-Ressource (102 p.)
    Keywords: Proteins
    Abstract: Liposomes have received increased attention in recent years. Nevertheless, liposomes, due to their various forms and applications, require further investigation. These structures can deliver both hydrophilic and hydrophobic drugs. The preparation of liposomes results in different properties for these systems. In addition, there are many factors and difficulties that affect the development of liposome drug delivery structures.The purpose of this book is to concentrate on recent developments in liposomes. The articles collected in this book are contributions by invited researchers with long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with a general background in many different biological sciences. This volume offers up-to-date, expert reviews of the fast-moving field of liposomes and is divided in two major sections: 1. Introduction; 2. Liposomes general properties
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    Molecular Medicine (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781839627606 , 9781839627590 , 9781839627613
    Language: English
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Proteins
    Abstract: Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies
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    Theory, Application, and Implementation of Monte Carlo Method in Science and Technology (2019)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789855463 , 9781789855456 , 9781839681523
    Language: English
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Computer modelling & simulation
    Abstract: The Monte Carlo method is a numerical technique to model the probability of all possible outcomes in a process that cannot easily be predicted due to the interference of random variables. It is a technique used to understand the impact of risk, uncertainty, and ambiguity in forecasting models. However, this technique is complicated by the amount of computer time required to achieve sufficient precision in the simulations and evaluate their accuracy. This book discusses the general principles of the Monte Carlo method with an emphasis on techniques to decrease simulation time and increase accuracy
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    Peripheral Membrane Proteins (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789235135 , 9781789235128 , 9781838816179
    Language: Undetermined
    Pages: 1 Online-Ressource (132 p.)
    Keywords: Proteins
    Abstract: The peripheral membrane proteins transduce the extracellular signaling into the cells. The peripheral membrane proteins include the G protein-coupled receptors, receptor tyrosine kinases, channels and transporters. The signals, which are transduced via the peripheral membrane proteins, activate several pathways including G protein signaling, MAPK signaling, TNF signaling, TGF? signaling, Wnt signaling and Hedgehog signaling. The peripheral membrane proteins transduce the signaling from the extracellular ligands into the cells. This book intends to provide a comprehensive overview of the features and signaling of peripheral membrane proteins, which includes the molecular structure and interaction. The insights into membrane proteins associated with diseases and therapeutics and the effects of drugs and chemicals are also discussed in this book
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    Ubiquitination Governing DNA Repair : Implications in Health and Disease (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789235852 , 9781789235845 , 9781838812645
    Language: Undetermined
    Pages: 1 Online-Ressource (220 p.)
    Keywords: Proteins
    Abstract: DNA damage response (DDR) and lesion repair are vital processes ensuring genome integrity through various pathways depending mainly on the nature of DNA injury and cell cycle stage. DDR is finely regulated at many levels in co-ordination with other ongoing processes as is genome replication and cell cycle progression. Posttranslational modifications (PTMs), affecting both protein-protein and protein-DNA interactions, play a crucial role in finely tuning all processes involved in the restoration of genome lesions. Regarding damaged chromatin, PTMs serve in many cases as recruitment platforms for DNA repair mechanisms by facilitating binding sites or regulating interactions between involved proteins. Ubiquitination, the addition of ubiquitin moieties on a target protein, apart from controlling protein availability through degradation, is also involved, together with partner small ubiquitin-like modifier (SUMO), in controlling many pathways involved in DDR by modifying the structure-function relationship and thus interacting with partner molecules. The aim of this book is to cover a broad spectrum of current topics in ubiquitination and to a lesser extent SUMOylation involvement in regulation of DDR and repair in health and disease. This book is intended for pre- and postgraduate students and young scientists in this field. Members of both academic and research institutions, actively involved in the field, have described their current understanding of major mechanisms involved, highlighted key events, described ongoing applications in both developmental diseases and cancer and provided hints for future potential applications
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    Petri Nets in Science and Engineering (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789236934 , 9781789236927 , 9781838816674
    Language: Undetermined
    Pages: 1 Online-Ressource (144 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book presents a collection of chapters from different areas of science and engineering, where Petri Nets have been shown to be a useful tool for the design and modeling of the problems that arise in such fields. The areas covered in this book include manufacturing systems, authentication and cyber-security, computer architectures, mechanical systems, process mining, control theory and time analysis. The main focus of the chapters was to be illustrative, to help the development of intuitive ideas that may guide the reader to adopt Petri Nets in their scientific or engineering work. However, there are other chapters with deep mathematical basis such as time analysis. Whenever possible, models, graphics and examples illustrate the developed concepts
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    Protein-Protein Interaction Assays (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789233919 , 9781789233902 , 9781838816087
    Language: Undetermined
    Pages: 1 Online-Ressource (90 p.)
    Keywords: Proteins
    Abstract: The chapters in this book are written by a team of well-reputed international researchers. The objective is to provide advanced and updated information related to protein-protein interactions. I hope the methods, resources and approaches described here will enhance the available knowledge of the reader significantly
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    Computational Fluid Dynamics : Basic Instruments and Applications in Science (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535137917 , 9789535137900 , 9789535140641
    Language: Undetermined
    Pages: 1 Online-Ressource (410 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book is the result of a careful selection of contributors in the field of CFD. It is divided into three sections according to the purpose and approaches used in the development of the contributions. The first section describes the "high-performance computing" (HPC) tools and their impact on CFD modeling. The second section is dedicated to "CFD models for local and large-scale industrial phenomena." Two types of approaches are basically contained here: one concerns the adaptation from global to local scale, - e.g., the applications of CFD to study the climate changes and the adaptations to local scale. The second approach, very challenging, is the multiscale analysis. The third section is devoted to "CFD in numerical modeling approach for experimental cases." Its chapters emphasize on the numerical approach of the mathematical models associated to few experimental (industrial) cases. Here, the impact and the importance of the mathematical modeling in CFD are focused on. It is expected that the collection of these chapters will enrich the state of the art in the CFD domain and its applications in a lot of fields. This collection proves that CFD is a highly interdisciplinary research area, which lies at the interface of physics, engineering, applied mathematics, and computer science
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    Finite Element Method : Simulation, Numerical Analysis and Solution Techniques (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535138501 , 9789535138495 , 9789535140795
    Language: Undetermined
    Pages: 1 Online-Ressource (322 p.)
    Keywords: Computer modelling & simulation
    Abstract: The book entitled Finite Element Method: Simulation, Numerical Analysis, and Solution Techniques aims to present results of the applicative research performed using FEM in various engineering fields by researchers affiliated to well-known universities. The book has a profound interdisciplinary character and is mainly addressed to researchers, PhD students, graduate and undergraduate students, teachers, engineers, as well as all other readers interested in the engineering applications of FEM. I am confident that readers will find information and challenging topics of high academic and scientific level, which will encourage them to enhance their knowledge in this engineering domain having a continuous expansion. The applications presented in this book cover a broad spectrum of finite element applications starting from mechanical, electrical, or energy production and finishing with the successful simulation of severe meteorological phenomena
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    Numerical Simulations in Engineering and Science (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789234510 , 9781789234503 , 9781838812836
    Language: Undetermined
    Pages: 1 Online-Ressource (404 p.)
    Keywords: Computer modelling & simulation
    Abstract: Computational science is one of the rapidly growing multidisciplinary fields. The high-performance computing capabilities are utilized to solve and understand complex problems. This book offers a detailed exposition of the numerical methods that are used in engineering and science. The chapters are arranged in such a way that the readers will be able to select the topics appropriate to their interest and need. The text features a broad array of applications of computational methods to science and technology. This book would be an interesting supplement for the practicing engineers, scientists, and graduate students
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    Molecular Dynamics (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789235258 , 9781789235241 , 9781838815035
    Language: Undetermined
    Pages: 1 Online-Ressource (100 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book is devoted to a description of the modeling of nanosystems and a detailed exposition of the application of molecular dynamics methods to problems from various fields of technology: material science, the formation of composite molecular complexes, and transport of nanosystems. The research results of the modeling of various nanosystems are presented: soft supramolecular nanostructures, nanosized beams of single-crystal Cu, metallic nanosized crystals, drug delivery systems, and systems stabilized by hydrogen bonds. The information from this book will be useful for engineers, technologists, researchers, and postgraduate students interested in the study of the whole complex of computer simulation based on the concept of molecular dynamics methods for the task of designing and producing nanomaterials with controlled properties
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    Non-Proteinogenic Amino Acids (2018)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9781789847291 , 9781789847284 , 9781838815974
    Language: English
    Pages: 1 Online-Ressource (72 p.)
    Keywords: Proteins
    Abstract: The first description of homocysteine (Hcy), a non-proteinogenic amino acid, was introduced in a case study more than 70 years ago. In recent years, numerous studies have shown a positive correlation between serum levels and various diseases, especially vascular pathology. Vitamins B6, B12, and folic acid play a major role in controlling homocysteine levels. In this book are presented both methods for the determination of homocysteine and its involvement in human pathology. Homocysteine levels can be taken as an early indicator for the detection of cardiovascular diseases because Hcy levels increase after a myocardial infarction or stroke
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    Computer Simulation (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535132066 , 9789535132059 , 9789535148074
    Language: Undetermined
    Pages: 1 Online-Ressource (266 p.)
    Keywords: Computer modelling & simulation
    Abstract: The first chapter provides an overview of the development of a novel agent-based simulation model of socio-environmental innovation diffusion. The second chapter shows the study about rendering of colours with three rendering engines. The third and fourth chapters are devoted to modelling clothes at different levels. The fifth chapter describes the modelling of computer simulation in the optimization of bioprocess technology. Chapters 6 and 7 formulate a physical model of deformation of steel and idea of constructing a scientific workshop focused on high-temperature processes. Chapter 8 formulates surrogate models. Chapter 9 shows computer simulation of high-frequency electromagnetic fields. Chapter 10 proposes the modelling of the task allocation problem by the use of Petri Nets. Chapter 11 presents various scenarios whose ranking is done according to defined criteria and weight coefficients
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    Uncertainty Quantification and Model Calibration (2017)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535132806 , 9789535132790 , 9789535147541
    Language: Undetermined
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Computer modelling & simulation
    Abstract: Uncertainty quantification may appear daunting for practitioners due to its inherent complexity but can be intriguing and rewarding for anyone with mathematical ambitions and genuine concern for modeling quality. Uncertainty quantification is what remains to be done when too much credibility has been invested in deterministic analyses and unwarranted assumptions. Model calibration describes the inverse operation targeting optimal prediction and refers to inference of best uncertain model estimates from experimental calibration data. The limited applicability of most state-of-the-art approaches to many of the large and complex calculations made today makes uncertainty quantification and model calibration major topics open for debate, with rapidly growing interest from both science and technology, addressing subtle questions such as credible predictions of climate heating
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    Modeling and Simulation in Engineering Sciences (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535126096 , 9789535126089 , 9789535141884
    Language: Undetermined
    Pages: 1 Online-Ressource (302 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book features state-of-the-art contributions in mathematical, experimental and numerical simulations in engineering sciences. The contributions in this book, which comprise twelve chapters, are organized in six sections spanning mechanical, aerospace, electrical, electronic, computer, materials, geotechnical and chemical engineering. Topics include metal micro-forming, compressible reactive flows, radio frequency circuits, barrier infrared detectors, fiber Bragg and long-period fiber gratings, semiconductor modelling, many-core architecture computers, laser processing of materials, alloy phase decomposition, nanofluids, geo-materials and rheo-kinetics. Contributors are from Europe, China, Mexico, Malaysia and Iran. The chapters feature many sophisticated approaches including Monte Carlo simulation, FLUENT and ABAQUS computational modelling, discrete element modelling and partitioned frequency-time methods. The book will be of interest to researchers and also consultants engaged in many areas of engineering simulation
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    Pluripotent Stem Cells : From the Bench to the Clinic (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535124726 , 9789535124719 , 9789535172871
    Language: English
    Pages: 1 Online-Ressource (532 p.)
    Keywords: Proteins
    Abstract: Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors
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    Numerical Simulation : From Brain Imaging to Turbulent Flows (2016)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535125655 , 9789535125648 , 9789535157847
    Language: English
    Pages: 1 Online-Ressource (440 p.)
    Keywords: Computer modelling & simulation
    Abstract: Nowadays mathematical modeling and numerical simulations play an important role in life and natural science. Numerous researchers are working in developing different methods and techniques to help understand the behavior of very complex systems, from the brain activity with real importance in medicine to the turbulent flows with important applications in physics and engineering. This book presents an overview of some models, methods, and numerical computations that are useful for the applied research scientists and mathematicians, fluid tech engineers, and postgraduate students
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    Progress in Stem Cell Transplantation (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535122272 , 9789535172734
    Language: English
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Proteins
    Abstract: This book documents the increased amount of stem cell-related research, basic and clinical applications as well as views for the future. The book covers a wide range of issues related to new developments and innovations in cell-based therapies discussed in basic and clinical chapters from authors around the world involved in stem cell studies and research. It thereby complements and extends the basic coverage of stem cells, such as mesenchymal stem cells, effect of stem cells on aging, cover hematopoietic stem cells, storage and cryopreservation, issues related to clinical applications such as haploidentical transplants and use of stem cells for the treatment of Huntingtons disease. Clearly, the treatment of various malignant and nonmalignant diseases depends heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments
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    Fourier Transform : Signal Processing and Physical Sciences (2015)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535121275 , 9789535157618
    Language: English
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Computer modelling & simulation
    Abstract: The application of Fourier transform (FT) in signal processing and physical sciences has increased in the past decades. Almost all the textbooks on signal processing or physics have a section devoted to the FT theory. For this reason, this book focuses on signal processing and physical sciences. The book chapters are related to fast hybrid recursive FT based on Jacket matrix, acquisition algorithm for global navigation satellite system, determining the sensitivity of output parameters based on FFT, convergence of integrals of products based on Riemann-Lebesgue Lemma function, extending the real and complex number fields for treating the FT, nonmaterial structure, Gabor transform, and chalcopyrite bioleaching. The book provides applications oriented to signal processing and physics written primarily for engineers, mathematicians, physicians and graduate students, will also find it useful as a reference for their research activities
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    Adult Stem Cell Niches (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535117186 , 9789535172208
    Language: English
    Pages: 1 Online-Ressource (330 p.)
    Keywords: Proteins
    Abstract: Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches
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    Computational and Numerical Simulations (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535112204 , 9789535157571
    Language: English
    Pages: 1 Online-Ressource (490 p.)
    Keywords: Computer modelling & simulation
    Abstract: Computational and Numerical Simulations is an edited book including 20 chapters. Book handles the recent research devoted to numerical simulations of physical and engineering systems. It presents both new theories and their applications, showing bridge between theoretical investigations and possibility to apply them by engineers of different branches of science. Numerical simulations play a key role in both theoretical and application oriented research
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    Pluripotent Stem Cell Biology : Advances in Mechanisms, Methods and Models (2014)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535115908 , 9789535172130
    Language: English
    Pages: 1 Online-Ressource (242 p.)
    Keywords: Proteins
    Abstract: Pluripotent stem cells have the potential to revolutionize treatment options for a range of diseases and conditions. This book presents recent advances in our understanding of the biological mechanisms of stem cell self-renewal, reprograming and regeneration. Also covered are novel methodological advances in the culture, purification and use of stem cells, as well as the ethical and moral dilemmas of embryo donation and adoption. These advances will shape the utilization of stem cells for future basic and applied applications
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  • 57
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    Future Aspects of Tumor Suppressor Gene (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535110637 , 9789535171249
    Language: English
    Pages: 1 Online-Ressource (232 p.)
    Keywords: Proteins
    Abstract: Tumor suppressor genes (TSGs) and their signaling networks are fast growing areas in current biomedical science. These groups of genes, which are not limited to tumor suppression, play critical roles in many cellular activities. This book, "Future Aspects of Tumor Suppressor Genes", contains some fascinating fields, from basic to translational researches, in recent TSG studies. For example, several TSG signaling pathways are addressed in this book, and both mouse and Drosophila models used for the exploration of these genes are described based on the experimental evidence. A detailed review for current knowledge of microRNA studies in the regulation of tumor growth is introduced. Additionally, how natural compounds interfere with the progression of cancer development via TSG pathways is systemically summarized. Recent progresses in cell reprogramming and stemness transition processes regulated by TSG pathways are also included in this book
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    Oxidative Stress and Chronic Degenerative Diseases : A Role for Antioxidants (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111238 , 9789535153740
    Language: English
    Pages: 1 Online-Ressource (514 p.)
    Keywords: Proteins
    Abstract: This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases
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    Neural Stem Cells : New Perspectives (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535110699 , 9789535171331
    Language: English
    Pages: 1 Online-Ressource (430 p.)
    Keywords: Proteins
    Abstract: Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these extremely promising, yet unresolved, issues
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    Innovations in Stem Cell Transplantation (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109808 , 9789535170877
    Language: English
    Pages: 1 Online-Ressource (380 p.)
    Keywords: Proteins
    Abstract: This book documents the increased number of stem cell related research, basic and clinical applications as well as views for the future. The book covers a wide range of issues related to new developments and innovations in cell-based therapies containing basic and clinical chapters from the respected authors involved in stem cell studies and research around the world. It thereby complements and extends the basic coverage of stem cells such as immunogenetics, neuron replacement therapy, cover hematopoietic stem cells, issues related to clinical problems, advanced HLA typing, alternative donor sources as well as gene therapy that employs novel methods in this field. Clearly, the treatment of various malignancies and biomedical engineering will depend heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments
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  • 61
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    Discrete Wavelet Transforms : A Compendium of New Approaches and Recent Applications (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535109402 , 9789535157182
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Computer modelling & simulation
    Abstract: Discrete Wavelet Transform is a wavelet (DWT) transform that is widely used in numerical and functional analysis. Its key advantage over more traditional transforms, such as the Fourier transform, lies in its ability to offer temporal resolution, i.e. it captures both frequency and location (or time) information. This book presents a succinct compendium of some of the more recent variants of DWTs and their use to come up with solutions to an array of problems transcending the traditional application areas of image/video processing and security to the relatively newer areas of medicine, artificial intelligence, power systems and telecommunications. The first of the two sections of this book contains three chapters devoted to traditional applications of DWTs in digital image compression, copyright protection and video resolution enhancement. The second section, comprising of five chapters, is devoted to variants of the DWT and their applications in humanoid-robot vision systems; modeling and simulation recognition of physiological and behavioral traits through human gait and facial images; assessment of agitation and sedation in intensive care patients; maximization of power control systems; and, finally, in demodulation of FM data in free-space optical control systems
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    Pluripotent Stem Cells (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111924 , 9789535171782
    Language: English
    Pages: 1 Online-Ressource (640 p.)
    Keywords: Proteins
    Abstract: Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same
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    Stem Cell Biology in Normal Life and Diseases (2013)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535111078 , 9789535171416
    Language: English
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Proteins
    Abstract: Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia)
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    Fuzzy Logic : Algorithms, Techniques and Implementations (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103936 , 9789535156864
    Language: English
    Pages: 1 Online-Ressource (296 p.)
    Keywords: Computer modelling & simulation
    Abstract: Fuzzy Logic is becoming an essential method of solving problems in all domains. It gives tremendous impact on the design of autonomous intelligent systems. The purpose of this book is to introduce Hybrid Algorithms, Techniques, and Implementations of Fuzzy Logic. The book consists of thirteen chapters highlighting models and principles of fuzzy logic and issues on its techniques and implementations. The intended readers of this book are engineers, researchers, and graduate students interested in fuzzy logic systems
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    Proteomic Applications in Biology (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076133 , 9789535151968
    Language: English
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Proteins
    Abstract: The past decade has seen the field of proteomics expand from a highly technical endeavor to a widely utilized technique. The objective of this book is to highlight the ways in which proteomics is currently being employed to address issues in the biological sciences. Although there have been significant advances in techniques involving the utilization of proteomics in biology, fundamental approaches involving basic sample visualization and protein identification still represent the principle techniques used by the vast majority of researchers to solve problems in biology. The work presented in this book extends from overviews of proteomics in specific biological subject areas to novel studies that have employed a proteomics-based approach. Collectively they demonstrate the power of established and developing proteomic techniques to characterize complex biological systems
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    Proteomics : Human Diseases and Protein Functions (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533078328 , 9789535151838
    Language: English
    Pages: 1 Online-Ressource (452 p.)
    Keywords: Proteins
    Abstract: Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research
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    Trends in Immunolabelled and Related Techniques (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105701 , 9789535152880
    Language: English
    Pages: 1 Online-Ressource (372 p.)
    Keywords: Proteins
    Abstract: The book is coined to provide a professional insight into the different trends of immunoassay and related techniques. It encompasses 22 chapters which are grouped into two sections. The first section consists of articles dealing with emerging uni-and-multiplex immunolabelled methods employed in the various areas of research. The second section includes review articles which introduce the researchers to some immunolabelled techniques which are of vital significance such as the use of the conjugates of the Staphylococcus aureus protein "A" and the Streptococcus Spps. protein "G" in immunolabelled assay systems, the use of bead-based assays and an overview on the laboratory assay systems. The book provides technological innovations that are expected to provide an efficient channel for developments in immunolabelled and related techniques. It is also most useful for researchers and post-graduate students, in all fields, where immunolabelled techniques are applicable
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    Advances in Discrete Time Systems (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535108757 , 9789535157205
    Language: English
    Pages: 1 Online-Ressource (258 p.)
    Keywords: Computer modelling & simulation
    Abstract: This volume brings about the contemporary results in the field of discrete-time systems. It covers papers written on the topics of robust control, nonlinear systems and recent applications. Although the technical views are different, they all geared towards focusing on the up-to-date knowledge gain by the researchers and providing effective developments along the systems and control arena. Each topic has a detailed discussions and suggestions for future perusal by interested investigators
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    Technology and Engineering Applications of Simulink (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535106357 , 9789535156512
    Language: English
    Pages: 1 Online-Ressource (268 p.)
    Keywords: Computer modelling & simulation
    Abstract: Building on MATLAB (the language of technical computing), Simulink provides a platform for engineers to plan, model, design, simulate, test and implement complex electromechanical, dynamic control, signal processing and communication systems. Simulink-Matlab combination is very useful for developing algorithms, GUI assisted creation of block diagrams and realisation of interactive simulation based designs. The eleven chapters of the book demonstrate the power and capabilities of Simulink to solve engineering problems with varied degree of complexity in the virtual environment
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    Enzyme Inhibition and Bioapplications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105855 , 9789535152941
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Proteins
    Abstract: Enzyme Inhibition and Bioapplications is a concise book on applied methods of enzymes used in drug testing. The present volume will serve the purpose of applied drug evaluation methods in research projects, as well as relatively experienced enzyme scientists who might wish to develop their experiments further. Chapters are arranged in the order of basic concepts of enzyme inhibition and physiological basis of cytochromes followed by new concepts of applied drug therapy; reliability analysis; and new enzyme applications from mechanistic point of view
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    Finite Volume Method : Powerful Means of Engineering Design (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104452 , 9789535156642
    Language: English
    Pages: 1 Online-Ressource (386 p.)
    Keywords: Computer modelling & simulation
    Abstract: We hope that among these chapters you will find a topic which will raise your interest and engage you to further investigate a problem and build on the presented work. This book could serve either as a textbook or as a practical guide. It includes a wide variety of concepts in FVM, result of the efforts of scientists from all over the world. However, just to help you, all book chapters are systemized in three general groups: New techniques and algorithms in FVM; Solution of particular problems through FVM and Application of FVM in medicine and engineering. This book is for everyone who wants to grow, to improve and to investigate
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    Protein Kinases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535106401 , 9789535153023
    Language: English
    Pages: 1 Online-Ressource (496 p.)
    Keywords: Proteins
    Abstract: Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development
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    Biomedicine (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535103523 , 9789535169208
    Language: English
    Pages: 1 Online-Ressource (214 p.)
    Keywords: Proteins
    Abstract: Comprehensive and systematic scientific researches in cell biology and molecular biology have promoted the evolution of traditional medicine. Scientists are now able to interpret a few perplexed medical difficulties with the emphasis on molecular levels. This book focuses on frontier progress in modern biomedical science dealing with regenerative medicine, gene medicine, nanobiomedicine, and medical devices. Each chapter is intently chosen and written by professional experts in the field of biomedical science. Biomedicine is a valuable guide for the readers to become aware of current advancement in rapidly moving field of biomedicine
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    Applications of Immunocytochemistry (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102298 , 9789535152354
    Language: English
    Pages: 1 Online-Ressource (332 p.)
    Keywords: Proteins
    Abstract: Immunocytochemistry is classically defined as a procedure to detect antigens in cellular contexts using antibodies. However, over the years many aspects of this procedure have evolved within a plethora of experimental setups. There are different ways to prepare a given specimen, different kinds of antibodies to apply, different techniques for imaging, and different methods of analyzing the data. In this book, various ways of performing each individual step of immunocytochemistry in different cellular contexts are exemplified and discussed. Applications of Immunocytochemistry offers technical and background information on different steps of immunocytochemistry and presents the application of this technique and its adaptations in cell lines, neural tissue, pancreatic tissue, sputum cells, sperm cells, preimplantation embryo, arabidopsis, fish gonads, and Leishmania
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    Modeling and Simulation in Engineering (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535100126 , 9789535155874
    Language: English
    Pages: 1 Online-Ressource (312 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book provides an open platform to establish and share knowledge developed by scholars, scientists, and engineers from all over the world, about various applications of the modeling and simulation in the design process of products, in various engineering fields. The book consists of 12 chapters arranged in two sections (3D Modeling and Virtual Prototyping), reflecting the multidimensionality of applications related to modeling and simulation. Some of the most recent modeling and simulation techniques, as well as some of the most accurate and sophisticated software in treating complex systems, are applied. All the original contributions in this book are jointed by the basic principle of a successful modeling and simulation process: as complex as necessary, and as simple as possible. The idea is to manipulate the simplifying assumptions in a way that reduces the complexity of the model (in order to make a real-time simulation), but without altering the precision of the results
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    Discrete Event Simulations : Development and Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535107415 , 9789535156710
    Language: English
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Computer modelling & simulation
    Abstract: The Discrete Event Simulation (DES) method has received widespread attention and acceptance by both researchers and practitioners in recent years. The range of application of DES spans across many different disciplines and research fields. In research, further development and advancements of the basic DES algorithm continue to be sought while various hybrid methods derived by combining DES with other simulation techniques continue to be developed. This book presents state-of-the-art contributions on fundamental development of the DES method, novel integration of the method with other modeling techniques as well as applications towards simulating and analyzing the performances of various types of systems. This book will be of interest to undergraduate and graduate students, researchers as well as professionals who are actively engaged in DES related work
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    Finite Element Analysis : From Biomedical Applications to Industrial Developments (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104742 , 9789535156659
    Language: English
    Pages: 1 Online-Ressource (510 p.)
    Keywords: Computer modelling & simulation
    Abstract: Finite Element Analysis represents a numerical technique for finding approximate solutions to partial differential equations as well as integral equations, permitting the numerical analysis of complex structures based on their material properties. This book presents 20 different chapters in the application of Finite Elements, ranging from Biomedical Engineering to Manufacturing Industry and Industrial Developments. It has been written at a level suitable for use in a graduate course on applications of finite element modelling and analysis (mechanical, civil and biomedical engineering studies, for instance), without excluding its use by researchers or professional engineers interested in the field, seeking to gain a deeper understanding concerning Finite Element Analysis
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    Molecular Dynamics : Studies of Synthetic and Biological Macromolecules (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535104445 , 9789535152712
    Language: English
    Pages: 1 Online-Ressource (446 p.)
    Keywords: Computer modelling & simulation
    Abstract: Molecular Dynamics is a two-volume compendium of the ever-growing applications of molecular dynamics simulations to solve a wider range of scientific and engineering challenges. The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as nanotechnology, energy research, and biology, due to the advances of new dynamics theories and the extraordinary power of today's computers. This second book begins with an introduction of molecular dynamics simulations to macromolecules and then illustrates the computer experiments using molecular dynamics simulations in the studies of synthetic and biological macromolecules, plasmas, and nanomachines. Coverage of this book includes: Complex formation and dynamics of polymers Dynamics of lipid bilayers, peptides, DNA, RNA, and proteins Complex liquids and plasmas Dynamics of molecules on surfaces Nanofluidics and nanomachines
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    Crosstalk and Integration of Membrane Trafficking Pathways (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535105152 , 9789535152729
    Language: English
    Pages: 1 Online-Ressource (260 p.)
    Keywords: Proteins
    Abstract: Membrane traffic is a broad field that studies the complex exchange of membranes that occurs inside the cell. Protein, lipids and other molecules traffic among intracellular organelles, and are delivered to, or transported from the cell surface by virtue of membranous carriers generally referred as "transport intermediates". These carriers have different shapes and sizes, and their biogenesis, modality of transport, and delivery to the final destination are regulated by a multitude of very complex molecular machineries. A concept that has clearly emerged in the last decade is that each membrane pathway does not represent a close system, but is fully integrated with all the other trafficking pathways. The aim of this book is to provide a general overview of the extent of this crosstalk
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    Applied Computational Fluid Dynamics (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535102717 , 9789535156499
    Language: English
    Pages: 1 Online-Ressource (356 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book is served as a reference text to meet the needs of advanced scientists and research engineers who seek for their own computational fluid dynamics (CFD) skills to solve a variety of fluid flow problems. Key Features: - Flow Modeling in Sedimentation Tank, - Greenhouse Environment, - Hypersonic Aerodynamics, - Cooling Systems Design, - Photochemical Reaction Engineering, - Atmospheric Reentry Problem, - Fluid-Structure Interaction (FSI), - Atomization, - Hydraulic Component Design, - Air Conditioning System, - Industrial Applications of CFD
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  • 81
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    Protein Purification (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078311 , 9789535151821
    Language: English
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Proteins
    Abstract: The current volume entitled Protein Purification is designed to facilitate rapid access to valuable information about various methodologies. It aims as well to provide an overview of state-of-art techniques for the purification, analysis and quantification of proteins in complex samples using different enrichment strategies
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  • 82
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    New Frontiers in Graph Theory (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535101154 , 9789535156055
    Language: English
    Pages: 1 Online-Ressource (528 p.)
    Keywords: Computer modelling & simulation
    Abstract: Nowadays, graph theory is an important analysis tool in mathematics and computer science. Because of the inherent simplicity of graph theory, it can be used to model many different physical and abstract systems such as transportation and communication networks, models for business administration, political science, and psychology and so on. The purpose of this book is not only to present the latest state and development tendencies of graph theory, but to bring the reader far enough along the way to enable him to embark on the research problems of his own. Taking into account the large amount of knowledge about graph theory and practice presented in the book, it has two major parts: theoretical researches and applications. The book is also intended for both graduate and postgraduate students in fields such as mathematics, computer science, system sciences, biology, engineering, cybernetics, and social sciences, and as a reference for software professionals and practitioners
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  • 83
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    Advances in Modeling of Fluid Dynamics (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535108344 , 9789535157014
    Language: English
    Pages: 1 Online-Ressource (318 p.)
    Keywords: Computer modelling & simulation
    Abstract: This book contains twelve chapters detailing significant advances and applications in fluid dynamics modeling with focus on biomedical, bioengineering, chemical, civil and environmental engineering, aeronautics, astronautics, and automotive. We hope this book can be a useful resource to scientists and engineers who are interested in fundamentals and applications of fluid dynamics
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  • 84
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    Numerical Simulation : From Theory to Industry (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107491 , 9789535156741
    Language: English
    Pages: 1 Online-Ressource (660 p.)
    Keywords: Computer modelling & simulation
    Abstract: Numerical Simulation - from Theory to Industry is the edited book containing 25 chapters and divided into four parts. Part 1 is devoted to the background and novel advances of numerical simulation; second part contains simulation applications in the macro- and micro-electrodynamics. Part 3 includes contributions related to fluid dynamics in the natural environment and scientific applications; the last, fourth part is dedicated to simulation in the industrial areas, such as power engineering, metallurgy and building. Recent numerical techniques, as well as software the most accurate and advanced in treating the physical phenomena, are applied in order to explain the investigated processes in terms of numbers. Since the numerical simulation plays a key role in both theoretical and industrial research, this book related to simulation of many physical processes, will be useful for the pure research scientists, applied mathematicians, industrial engineers, and post-graduate students
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  • 85
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    Haptics Rendering and Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533078977 , 9789535155768
    Language: English
    Pages: 1 Online-Ressource (248 p.)
    Keywords: Computer modelling & simulation
    Abstract: There has been significant progress in haptic technologies but the incorporation of haptics into virtual environments is still in its infancy. A wide range of the new society's human activities including communication, education, art, entertainment, commerce and science would forever change if we learned how to capture, manipulate and reproduce haptic sensory stimuli that are nearly indistinguishable from reality. For the field to move forward, many commercial and technological barriers need to be overcome. By rendering how objects feel through haptic technology, we communicate information that might reflect a desire to speak a physically- based language that has never been explored before. Due to constant improvement in haptics technology and increasing levels of research into and development of haptics-related algorithms, protocols and devices, there is a belief that haptics technology has a promising future
    Note: English
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  • 86
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    New Advances in Stem Cell Transplantation (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535100133 , 9789535167983
    Language: English
    Pages: 1 Online-Ressource (596 p.)
    Keywords: Proteins
    Abstract: This book documents the increased number of stem cell-related research, clinical applications, and views for the future. The book covers a wide range of issues in cell-based therapy and regenerative medicine, and includes clinical and preclinical chapters from the respected authors involved with stem cell studies and research from around the world. It complements and extends the basics of stem cell physiology, hematopoietic stem cells, issues related to clinical problems, tissue typing, cryopreservation, dendritic cells, mesenchymal cells, neuroscience, endovascular cells and other tissues. In addition, tissue engineering that employs novel methods with stem cells is explored. Clearly, the continued use of biomedical engineering will depend heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments
    Note: English
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  • 87
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    MATLAB : A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 2 (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107514 , 9789535157076
    Language: English
    Pages: 1 Online-Ressource (326 p.)
    Keywords: Computer modelling & simulation
    Abstract: This excellent book represents the second part of three-volumes regarding MATLAB- based applications in almost every branch of science. The present textbook contains a collection of 13 exceptional articles. In particular, the book consists of three sections, the first one is devoted to electronic engineering and computer science, the second is devoted to MATLAB/SIMULINK as a tool for engineering applications, the third one is about Telecommunication and communication systems and the last one discusses MATLAB toolboxes
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  • 88
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    MATLAB : A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 3 (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107521 , 9789535157083
    Language: English
    Pages: 1 Online-Ressource (502 p.)
    Keywords: Computer modelling & simulation
    Abstract: This excellent book represents the final part of three-volumes regarding MATLAB-based applications in almost every branch of science. The book consists of 19 excellent, insightful articles and the readers will find the results very useful to their work. In particular, the book consists of three parts, the first one is devoted to mathematical methods in the applied sciences by using MATLAB, the second is devoted to MATLAB applications of general interest and the third one discusses MATLAB for educational purposes. This collection of high quality articles, refers to a large range of professional fields and can be used for science as well as for various educational purposes
    Note: English
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  • 89
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    Advances in Protein Kinases (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535106333 , 9789535153016
    Language: English
    Pages: 1 Online-Ressource (386 p.)
    Keywords: Proteins
    Abstract: Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development
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  • 90
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    Embryology : Updates and Highlights on Classic Topics (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535104650 , 9789535169505
    Language: English
    Pages: 1 Online-Ressource (224 p.)
    Keywords: Proteins
    Abstract: Embryology is a branch of science concerned with the morphological aspects of organismal development. The genomic and molecular revolution of the second half of the 20th century, together with the classic descriptive aspects of this science have allowed greater integration in our understanding of many developmental events. Through such integration, modern embryology seeks to provide practical knowledge that can be applied to assisted reproduction, stem cell therapy, birth defects, fetal surgery and other fields. This book focuses on human embryology and aims to provide an up-to-date source of information on a variety of selected topics. The book consists of nine chapters organized into three sections, namely: 1) gametes and infertility, 2) implantation, placentation and early development, and 3) perspectives in embryology. The contents of this book should be of interest to biology and medical students, clinical embryologists, laboratory researchers, obstetricians and urologists, developmental biologists, molecular geneticists and anyone who wishes to know more about recent advances in human development
    Note: English
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  • 91
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    MATLAB : A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 1 (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789535107507 , 9789535156666
    Language: English
    Pages: 1 Online-Ressource (536 p.)
    Keywords: Computer modelling & simulation
    Abstract: This is the first book in a three-volume series deploying MATLAB-based applications in almost every branch of science. This volume, presents interesting topics from different areas of engineering, signal and image processing based on the MATLAB environment. The book consists of 20 excellent, insightful articles and the readers will find the results very useful to their work. This collection of high quality articles, refers to a large range of professional fields and may be used for scientific, engineering and educational purposes
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  • 92
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    Fluid Dynamics, Computational Modeling and Applications (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789535100522 , 9789535156505
    Language: English
    Pages: 1 Online-Ressource (662 p.)
    Keywords: Computer modelling & simulation
    Abstract: The content of this book covers several up-to-date topics in fluid dynamics, computational modeling and its applications, and it is intended to serve as a general reference for scientists, engineers, and graduate students. The book is comprised of 30 chapters divided into 5 parts, which include: winds, building and risk prevention; multiphase flow, structures and gases; heat transfer, combustion and energy; medical and biomechanical applications; and other important themes. This book also provides a comprehensive overview of computational fluid dynamics and applications, without excluding experimental and theoretical aspects
    Note: English
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  • 93
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    Neural Stem Cells and Therapy (2012)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533079585 , 9789535167730
    Language: English
    Pages: 1 Online-Ressource (454 p.)
    Keywords: Proteins
    Abstract: This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy
    Note: English
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  • 94
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    Embryonic Stem Cells : The Hormonal Regulation of Pluripotency and Embryogenesis (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533071961 , 9789535164302
    Language: English
    Pages: 1 Online-Ressource (690 p.)
    Keywords: Proteins
    Abstract: Pluripotency is a prerequisite for the subsequent coordinated differentiation of embryonic stem cells into all tissues of the body. This book describes recent advances in our understanding of pluripotency and the hormonal regulation of embryonic stem cell differentiation into tissue types derived from the ectoderm, mesoderm and endoderm
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  • 95
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    Discrete Time Systems (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533072005 , 9789535155102
    Language: English
    Pages: 1 Online-Ressource (540 p.)
    Keywords: Computer modelling & simulation
    Abstract: Discrete-Time Systems comprehend an important and broad research field. The consolidation of digital-based computational means in the present, pushes a technological tool into the field with a tremendous impact in areas like Control, Signal Processing, Communications, System Modelling and related Applications. This book attempts to give a scope in the wide area of Discrete-Time Systems. Their contents are grouped conveniently in sections according to significant areas, namely Filtering, Fixed and Adaptive Control Systems, Stability Problems and Miscellaneous Applications. We think that the contribution of the book enlarges the field of the Discrete-Time Systems with signification in the present state-of-the-art. Despite the vertiginous advance in the field, we also believe that the topics described here allow us also to look through some main tendencies in the next years in the research area
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  • 96
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    Practical Applications and Solutions Using LabVIEW™ Software (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076508 , 9789535155515
    Language: English
    Pages: 1 Online-Ressource (488 p.)
    Keywords: Computer modelling & simulation
    Abstract: The book consists of 21 chapters which present interesting applications implemented using the LabVIEW environment, belonging to several distinct fields such as engineering, fault diagnosis, medicine, remote access laboratory, internet communications, chemistry, physics, etc. The virtual instruments designed and implemented in LabVIEW provide the advantages of being more intuitive, of reducing the implementation time and of being portable. The audience for this book includes PhD students, researchers, engineers and professionals who are interested in finding out new tools developed using LabVIEW. Some chapters present interesting ideas and very detailed solutions which offer the immediate possibility of making fast innovations and of generating better products for the market. The effort made by all the scientists who contributed to editing this book was significant and as a result new and viable applications were presented
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  • 97
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    Scientific and Engineering Applications Using MATLAB (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533076591 , 9789535155898
    Language: English
    Pages: 1 Online-Ressource (216 p.)
    Keywords: Computer modelling & simulation
    Abstract: The purpose of this book is to present 10 scientific and engineering works whose numerical and graphical analysis were all constructed using the power of MATLAB® tools. The first five chapters of this book show applications in seismology, meteorology and natural environment. Chapters 6 and 7 focus on modeling and simulation of Water Distribution Networks. Simulation was also applied to study wide area protection for interconnected power grids (Chapter 8) and performance of conical antennas (Chapter 9). The last chapter deals with depth positioning of underwater robot vehicles. Therefore, this book is a collection of interesting examples of where this computational package can be applied
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  • 98
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    Two Phase Flow, Phase Change and Numerical Modeling (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
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    ISBN: 9789533075846 , 9789535155690
    Language: English
    Pages: 1 Online-Ressource (598 p.)
    Keywords: Computer modelling & simulation
    Abstract: The heat transfer and analysis on laser beam, evaporator coils, shell-and-tube condenser, two phase flow, nanofluids, complex fluids, and on phase change are significant issues in a design of wide range of industrial processes and devices. This book includes 25 advanced and revised contributions, and it covers mainly (1) numerical modeling of heat transfer, (2) two phase flow, (3) nanofluids, and (4) phase change. The first section introduces numerical modeling of heat transfer on particles in binary gas-solid fluidization bed, solidification phenomena, thermal approaches to laser damage, and temperature and velocity distribution. The second section covers density wave instability phenomena, gas and spray-water quenching, spray cooling, wettability effect, liquid film thickness, and thermosyphon loop. The third section includes nanofluids for heat transfer, nanofluids in minichannels, potential and engineering strategies on nanofluids, and heat transfer at nanoscale. The forth section presents time-dependent melting and deformation processes of phase change material (PCM), thermal energy storage tanks using PCM, phase change in deep CO2 injector, and thermal storage device of solar hot water system. The advanced idea and information described here will be fruitful for the readers to find a sustainable solution in an industrialized society
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  • 99
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    Applications of MATLAB in Science and Engineering (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533077086 , 9789535155928
    Language: English
    Pages: 1 Online-Ressource (524 p.)
    Keywords: Computer modelling & simulation
    Abstract: The book consists of 24 chapters illustrating a wide range of areas where MATLAB tools are applied. These areas include mathematics, physics, chemistry and chemical engineering, mechanical engineering, biological (molecular biology) and medical sciences, communication and control systems, digital signal, image and video processing, system modeling and simulation. Many interesting problems have been included throughout the book, and its contents will be beneficial for students and professionals in wide areas of interest
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  • 100
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    Discrete Wavelet Transforms : Algorithms and Applications (2011)
    [Erscheinungsort nicht ermittelbar] : IntechOpen
    Details
    ISBN: 9789533074825 , 9789535155508
    Language: English
    Pages: 1 Online-Ressource (310 p.)
    Keywords: Computer modelling & simulation
    Abstract: The discrete wavelet transform (DWT) algorithms have a firm position in processing of signals in several areas of research and industry. As DWT provides both octave-scale frequency and spatial timing of the analyzed signal, it is constantly used to solve and treat more and more advanced problems. The present book: Discrete Wavelet Transforms: Algorithms and Applications reviews the recent progress in discrete wavelet transform algorithms and applications. The book covers a wide range of methods (e.g. lifting, shift invariance, multi-scale analysis) for constructing DWTs. The book chapters are organized into four major parts. Part I describes the progress in hardware implementations of the DWT algorithms. Applications include multitone modulation for ADSL and equalization techniques, a scalable architecture for FPGA-implementation, lifting based algorithm for VLSI implementation, comparison between DWT and FFT based OFDM and modified SPIHT codec. Part II addresses image processing algorithms such as multiresolution approach for edge detection, low bit rate image compression, low complexity implementation of CQF wavelets and compression of multi-component images. Part III focuses watermaking DWT algorithms. Finally, Part IV describes shift invariant DWTs, DC lossless property, DWT based analysis and estimation of colored noise and an application of the wavelet Galerkin method. The chapters of the present book consist of both tutorial and highly advanced material. Therefore, the book is intended to be a reference text for graduate students and researchers to obtain state-of-the-art knowledge on specific applications
    Note: English
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