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  • MPI Ethno. Forsch.  (1,138)
  • Kalliope (Nachlässe)
  • 2020-2024  (1,138)
  • 1955-1959
  • Medicine  (1,138)
Datasource
Material
Language
Years
Year
Subjects(RVK)
  • 1
    Language: English
    Pages: 2 volumes
    Series Statement: Classic reprint series
    Parallel Title: Nachdruck von Winterbottom, Thomas Masterman An account of the native Africans in the neighbourhood of Sierra Leone, to which is added an account of the present state of medicine among them
    Keywords: Medicine
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  • 2
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031388057
    Language: English
    Pages: 1 Online-Ressource(XV, 223 p. 3 illus.)
    Edition: 1st ed. 2024.
    Series Statement: Medicine and Biomedical Sciences in Modern History
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Imperialism. ; Medicine ; Science ; Europe ; History, Modern.
    Abstract: 1 Introduction: The Age of Empire, The Making of the Modern Nation and the Advancement of Medical Sciences; Mauro Capocci and Daniele Cozzoli- Part I. Tropical Medicine in the Evolution and the Collapse of Empires -- 2. Tropical Medicine and the “Consolidation” of the Portuguese Empire, 1902-1966; Isabel Amaral -- 3. Dutch Colonial Medicine and Empire-building in the Tropics: The Cases of Leprosy and Drug Use in the Dutch East and West Indies; Stephen Snelders -- Part II. Tropical Medical Institutions and Imperial Commercial and Political Expansion -- 4. The Business of Tropical Medicine: Connections between Anti-malarial Campaigns in Sierra Leone, 1899-1901, and Jamaica, 1908; Juanita De Barros -- 5. Leishmaniases in Brazil: A Historical Approach; Jaime Larry Benchimol -- Part III. Circulation of People, Objects and Ideas -- 6. Tropical Medicine, the Nation, and Colonial Expansion in the View of Italian Royal Navy Physicians at the End of the Nineteenth Century; Mauro Capocci and Daniele Cozzoli -- 7. From Universal Rats to Future Jungle Foci: Actors and Places of Plague in Brazil, 1899-1940s; Matheus Alves Duarte da Silva -- 8. Anti-fascist Medicine and the International Peace Campaign against Urban Raids in Spain and China, 1936-1939; Carles Brasó Broggi.
    Abstract: This book investigates the complex relationship between the development of modern empires, nation, and the history of tropical medicine. Broadening existing historiographical perspectives, it explores imperialism outside of the British Empire, drawing on case studies from other colonial experiences in Africa, Asia, and South America in the late-nineteenth and early-twentieth century. Each of these systems adopted different approaches to colonial health and medicine. By studying their diversity, it is possible to obtain a more comprehensive picture of what we now call ‘tropical medicine.’ The authors emphasise that the British model cannot be adapted to all colonial experiences, drawing on relevant cases from both interoceanic and continental empires. The collection comprises three sections. The first examines the role of tropical medicine in the evolution and collapse of empire in countries such as Portugal and the Netherlands. The second part analyses the links between tropical medical institutions and imperial commercial and political expansion in Britain and Brazil. Finally, the authors tackle the crucial interrelated circulation of people, objects, and ideas amongst countries including Brazil, China, Italy, and Spain. Using a medical lens to analyse the inter-connected processes of nation-building and colonial expansion in the late-nineteenth and early-twentieth centuries, this book provides valuable reading for scholars of imperialism and medical history alike.
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  • 3
    ISBN: 9783839471906 , 9783837671902
    Language: Undetermined
    Pages: 1 Online-Ressource (364 p.)
    Series Statement: Medical Humanities
    Keywords: Social, group or collective psychology ; Psychoanalytical theory (Freudian psychology) ; Medicine: general issues ; Biographie ; Erzählung ; Lebensgeschichte ; Wiedererzählung ; Interview ; Narratives Interview ; Identität ; Lebensgestaltung ; Medizin ; Therapie ; Krankheit ; Selbsterzählung ; Kultur ; Sprache ; Sozialpsychologie ; Psychoanalyse ; Kulturwissenschaft ; Biography ; Narrative ; Retelling ; Narrative Interview ; Identity ; Life Design ; Medicine ; Therapy ; Illness ; Culture ; Language ; Social Psychology ; Psychoanalysis ; Cultural Studies
    Abstract: Wie erzählen Menschen ihre Lebensgeschichten? Und wie verändern sich diese Erzählungen im Laufe der Zeit? Shevek K. Selbert widmet sich an der Schnittstelle von Biographieforschung, Psychologie und Erzählforschung vollumfänglich wiederholten biographisch-narrativen Interviews, die im Abstand von zehn Jahren geführt wurden. Als Pionierarbeit qualitativer Längsschnittforschung entwickelt er Methoden, um die Erzählversionen miteinander zu vergleichen - und bietet einen einzigartigen Einblick in die Dynamik sowie die (auch therapeutische) Bedeutung von Selbsterzählungen für die Identitätsbildung und die Lebensgestaltung
    Note: German
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  • 4
    Online Resource
    Online Resource
    Singapore : Springer Nature Singapore | Singapore : Imprint: Palgrave Macmillan
    ISBN: 9789819714711
    Language: English
    Pages: 1 Online-Ressource (VII, 155 p. 35 illus., 34 illus. in color.)
    Series Statement: Palgrave pivot
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Asia ; Medicine ; Biology ; Technological innovations. ; biotech ; pharmaceutical industry ; biopharmaceutical research ; sino-european trade ; innovation
    Abstract: Chapter 1: The Chinese healthcare and pharmaceutical market: Ignore at your own peril -- Chapter 2: China regulatory and legal reforms: Gateway to innovation and global integration -- Chapter 3: The golden age of the Chinese biopharma: Explosive growth in a thriving ecosystem -- Chapter 4: Innovation in the Chinese biopharma: From me-too to First-in-class -- Chapter 5: The art of the biopharma deal: The China angle -- Chapter 6: End if the first cycle. A drastic rest, future challenges and opportunities.
    Abstract: This book provides an insider’s overview of the emerging Chinese biopharma sector, its dynamics and trends, first bust and boom cycle, long-term perspectives, and how as a foreign company or investor to tap into this. China has gone from a country with no innovation in drug discovery, to a country which starts to out-license its biopharma technology to the rest of the world. The Chinese biopharma sector is only a decade old, but it already has become a new driver of growth and value. The book takes a closer look at what drives Chinese innovation in the biopharma sector, how to deal with this innovation, and what opportunities and challenges this provides for foreign companies. The book also takes a deep dive into its first biopharma boom and bust cycle, and what it means for the sector. It also explains what deals Chinese biopharma companies and investors are looking for, what works and what doesn’t, and how as a foreign company can tap into the world’s second largest healthcare market. Ben Wu has close to 30 years of experience in the pharmaceutical industry, holding senior executive positions in the Asia Pacific region for multinationals like J&J and Sanofi. He was active in several China originated biopharma companies, and is the founding CEO of Citrine Medicine, a venture capital backed biopharma. Originally from Belgium, Sven Agten has been living and working in China since 2004. He is a seasoned business executive working for SMEs and multinationals, with in-depth experience about business in China. He has published several books about China, all related to China business challenges, trends and opportunities.
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  • 5
    ISBN: 9783031393556 , 9783031393549
    Language: Undetermined
    Pages: 1 Online-Ressource (810 p.)
    Series Statement: Health Informatics
    Keywords: Medical equipment and techniques ; Information technology: general topics ; Nursing and ancillary services ; Computer science ; Biology, life sciences ; Public health and preventive medicine ; Predictive analytics ; Artificial intelligence ; Medicine ; Machine learning ; Causal discovery ; Causal inference ; Genomics ; Medical knowledge discovery ; Clinical risk models ; Clinical risk stratification
    Abstract: This open access book provides a detailed review of the latest methods and applications of artificial intelligence (AI) and machine learning (ML) in medicine. With chapters focusing on enabling the reader to develop a thorough understanding of the key concepts in these subject areas along with a range of methods and resulting models that can be utilized to solve healthcare problems, the use of causal and predictive models are comprehensively discussed. Care is taken to systematically describe the concepts to facilitate the reader in developing a thorough conceptual understanding of how different methods and resulting models function and how these relate to their applicability to various issues in health care and medical sciences. Guidance is also given on how to avoid pitfalls that can be encountered on a day-to-day basis and stratify potential clinical risks. Artificial Intelligence and Machine Learning in Health Care and Medical Sciences: Best Practices and Pitfallsis a comprehensive guide to how AI and ML techniques can best be applied in health care. The emphasis placed on how to avoid a variety of pitfalls that can be encountered makes it an indispensable guide for all medical informatics professionals and physicians who utilize these methodologies on a day-to-day basis. Furthermore, this work will be of significant interest to health data scientists, administrators and to students in the health sciences seeking an up-to-date resource on the topic
    Note: English
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  • 6
    ISBN: 9783839466049 , 9783837666045
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Series Statement: Gesundheit, Kommunikation und Gesellschaft
    Keywords: Social work ; Medicine: general issues ; Soziale Arbeit ; Medizinische Rehabilitation ; Wirkung ; Gesundheit ; Pflege ; Reha ; Zusammenarbeit ; Teilhabe ; Körper ; Medizin ; Sozialarbeit ; Public Health ; Social Work ; Health-related Rehabilitation ; Effect ; Health ; Care ; Cooperation ; Participation ; Body ; Medicine
    Abstract: Soziale Arbeit ist ein wichtiger Teil der medizinischen Rehabilitation. Die Ausgestaltung ihrer Leistungen und ihre potentielle Wirkung blieben bislang allerdings unklar. An dieser Stelle setzen die Autor*innen an und präsentieren die Ergebnisse des Forschungsprojekts SWIMMER: Im Rahmen eines qualitativen Forschungsprojekts wurde die sozialarbeiterische Praxis von Sozialdiensten medizinischer Reha-Einrichtungen untersucht und ein Wirkmodell der Sozialen Arbeit in diesem Bereich entwickelt. Die vergleichende Darstellung der Resultate richtet sich sowohl an Sozialarbeiter*innen als auch an Verantwortliche in den Reha-Einrichtungen, die ihre eigene Praxis reflektieren und einen tieferen Einblick in gängige Arbeitsstrukturen der Sozialdienste erhalten wollen
    Note: German
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  • 7
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Springer
    ISBN: 9783031294365
    Language: English
    Pages: 1 Online-Ressource(XVI, 227 p. 219 illus.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als Buick, Adam Intellectual property rights in pharmaceutical test data
    RVK:
    Keywords: Information technology—Law and legislation. ; Mass media—Law and legislation. ; Medicine—Research. ; Biology—Research. ; Medical laws and legislation. ; Mass media ; Information technology ; Medicine ; Biology
    Abstract: Chapter 1 – Introduction -- Chapter 2 – An overview of the protection of submitted test data -- Chapter 3 – The origins of test data exclusivity -- Chapter 4 – The protection of submitted test data and the TRIPS Agreement -- Chapter 5 – The globalisation of test data exclusivity -- Chapter 6 – Approaches to the Implementation of the Protection of Submitted Test Data -- Chapter 7 – The impact of test data exclusivity -- Chapter 8 – The Impact of Test Data Exclusivity on Measures for the Protection of Public Health -- Chapter 9 – Conclusion.
    Abstract: This book considers the intellectual property protection of clinical test data that has been submitted to governments, in particular through test data exclusivity rights. It focuses on how these intellectual property rights first emerged in the early 1980s, how they have globalised over the past four decades, and what impact they have had upon access to medicine. This book makes a number of significant and original contributions to the literature around the protection of submitted test data. First, the book draws upon the theory of regulatory globalisation to provide an explanation of how intellectual property rights in submitted pharmaceutical test data have become nearly ubiquitous in the legal systems of most major economies. Second, through a comprehensive analysis and synthesis of provisions on the protection of submitted test data in free trade agreements, as well as a comparison of a range of national approaches to the protection of submitted test data, it reveals the broader global regulatory pattern that has given rise to these intellectual property rights. Third, by analysing data on drug approvals in the US, it provides an empirical insight into the impact of test data exclusivity in national pharmaceutical markets. Fourth, the book covers a number of developments regarding test data exclusivity that have occurred as a result of responses to the COVID-19 pandemic, both at the national level as well as at the World Trade Organisation (WTO). This book will appeal to academics researching the intersection of intellectual property and the life sciences, civil society activists working to promote access to medicines, and students (particularly those at the post-graduate level) studying the relationship between intellectual property and medicine.
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  • 8
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031128981
    Language: English
    Pages: 1 Online-Ressource(XIII, 296 p. 2 illus.)
    Edition: 1st ed. 2023.
    Series Statement: Palgrave Studies in Medieval and Early Modern Medicine
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Science—History. ; Medicine—History. ; Europe—History—476-1492. ; Philosophy—History. ; Religion—History. ; Science ; Medicine ; Europe ; Philosophy ; Religion
    Abstract: 1. Introduction -- 2. Roger Bacon and the Unnatural State of Man -- 3. Learning to Prolong Life -- 4. The Corpus Equale -- 5. Medicines and their Effects on the Body -- 6. Debate and Authority in the Reshaping of Medicine -- 7. Franciscan Understanding of the Ideal Human Body -- 8. Conclusion.
    Abstract: This book examines Roger Bacon’s alchemical theories, and explains how he believed that the key to extending life lay not in the curricula as taught in the medical faculties of the universities, but in the study of alchemy. Though twelfth- and thirteenth-century alchemy was generally concerned with the transmutation of metals, Bacon’s alchemy was a much larger area of study, and encompassed the generation and corruption of all material things in the sublunary world. It was this aspect of alchemy, which Bacon referred to as speculative alchemy, that explained how the four elements of fire, air, water, and earth interacted with each other to make the basis of reality as man could know it. Thus, the study of alchemy in conjunction with humoral medicine could explain not only how the human body worked, but how it interacted with the materials around it, illuminating the method of prolonging life to extreme lengths. .
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  • 9
    Online Resource
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    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031131059
    Language: English
    Pages: 1 Online-Ressource(XXII, 378 p. 12 illus.)
    Edition: 1st ed. 2023.
    Series Statement: Mental Health in Historical Perspective
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: France—History. ; Great Britain—History. ; Medicine—History. ; Science—History. ; Labor. ; History. ; Medicine ; Science ; France ; Great Britain
    Abstract: 1. Introduction -- 2. Patient Work before the First World War -- 3. From Alienism to Psychiatry -- 4. New Approaches to Patient Work and Occupation -- 5. Money and Management -- 6. The Medical Prescription of Patient Occupation -- 7. The Supervision of Patient Occupation -- 8. The Patient Workers Inside Hospital -- 9. Work and Support for Patients Outside Hospital -- Conclusions.
    Abstract: Jane Freebody offers a fresh perspective on life in the asylum in both England and France which will be of interest to historians of the institutional everyday as well as historians of psychiatry. In this fascinating and original study, she not only focuses on the less examined interwar period and the importance of patient occupation, but, most strikingly, takes a comparative analysis that goes beyond the transnational into more detailed considerations of place; with an insightful evaluation of the metropolitan versus the provincial in shaping institutional responses. Clare Hickman, Reader in Environmental and Medical History, University of Newcastle, UK. This ambitious exploration of patient occupation in interwar French and English mental institutions sheds light on a hitherto under-investigated aspect of life in the asylum – the nature, meaning and therapeutic implications of work for asylum regimes, staff and patients. This is an important and original study of value for anyone interested in twentieth-century psychiatry and institutional practices. Hilary Marland, Professor of History, Centre for the History of Medicine, University of Warwick, UK. This open access book demonstrates that, while occupation has been used to treat the mentally disordered since the early nineteenth century, approaches to its use have varied across time and place. Comparing how work and occupation were used in French and English mental institutions between 1918 and 1939, one hundred years after the heyday of moral therapy, this open access book is an essential read for those researching the history of mental health and medicine more generally. Jane Freebody is a historian of medicine whose research interests revolve around nineteenth- and twentieth-century psychiatry and mental health in France and England. She is an Associate Lecturer at Oxford Brookes University, UK, where she previously gained her Wellcome Trust-funded doctorate.
    Note: Open Access
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  • 10
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031427251
    Language: English
    Pages: 1 Online-Ressource(XXII, 265 p. 24 illus., 10 illus. in color.)
    Edition: 1st ed. 2023.
    Series Statement: Mental Health in Historical Perspective
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als Bates, Gordon David Lyle The uncanny rise of medical hypnotism, 1888-1914
    Keywords: Great Britain ; Medicine ; Psychology. ; Social sciences ; Intellectual life ; Social history.
    Abstract: 1: Introduction -- 2: The New Hypnotists -- 3: The Limits of the Imagination -- 4: The Power of Suggestion -- 5: A Very British History of Hypnotism -- 6: The Medical Contest for Hypnotism in the 1890s -- 7: Hypnotism in the Public Sphere -- 8: Social Networks and Hypnotic Influences -- 9: Imaginary Hypnotism -- 10: The Triumph of Medical Hypnotism -- 11: Post-hypnotic Suggestion: WWI and Beyond.
    Abstract: This book explores the improbable rise of medical hypnotism in Victorian Britain and its subsequent assimilation and neglect. It follows the careers of the ‘New Hypnotists’: Charles Lloyd Tuckey, John Milne Bramwell, George Kingsbury and Robert Felkin. This loosely knit group all trained with the Suggestion School of Nancy and published books on hypnotism. They had to confront the many public and medical prejudices against the trance state which had persisted after the scandalous disgrace of John Elliotson and medical mesmerism, fifty years before. Hypnotism was a highly contested technology and in the 1890s the debates about safety and utility were fought in the national newspapers as well as the medical journals. The new hypnotists took on the might of the medical institutions personified by Ernest Hart, Editor of the British Medical Journal. However their timing was propitious, as the rise of faith-healing forced the medical profession to confront the non-physical therapeutic aspects of the doctor-patient relationship. The hypnotic discourse was shaped by these developments, but also by the fascination of the general public, novelists, occultists, psychic investigators, educationalists and spiritualists in the myriad possibilities of the trance state. Despite growing interest in the prehistory of British psychology and talking therapies, and the recent challenges to the primacy of Freudian histories, there are few accounts of the development of British ‘eclectic therapy’. This book uses the New Hypnotists as a lens to examine Victorian medicine and society, exploring their role in establishing the term ‘psychotherapy,’ and legitimising medical hypnotism, a precursor of psychological therapies. Gordon Bates is a Consultant Psychiatrist and Postdoctoral Researcher at Birkbeck, University of London, in the UK. He was made a fellow of the Royal College of Psychiatrists and has held posts at the Universities of Birmingham and Warwick. Gordon has published over twenty articles in scientific journals and contributed chapters to edited books. He is the medical humanities editor of the journal, Child and Adolescent Mental Health.
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  • 11
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036595665 , 9783036595672
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Medicine ; Oncology
    Abstract: This Special Issue in Cancers is focused on cell therapy, bispecific antibodies, and other immunotherapies against cancer. It includes reports on cell therapies such as CAR-NK cell therapies, and bispecific antibodies against multiple myeloma and B cell lymphoma. Immunotherapies against solid tumors include TGF-beta-PDL-1 fusion protein and EpCAM-CD3 bispecific antibody generated with mRNA-lipid nanoparticles (LNP) against colorectal tumors. The clinical studies ongoing with bi- and tri-specific T cell engager antibodies against solid tumors and advantages versus cell therapies are discussed. This Special Issue highlights novel approaches to cell therapies, bispecific antibodies, vaccines, and immunotherapies that will be interesting for cancer cell researchers, biologists, and oncologists
    Note: English
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  • 12
    Online Resource
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036595306 , 9783036595313
    Language: Undetermined
    Pages: 1 Online-Ressource (240 p.)
    Keywords: Medicine
    Abstract: Understanding the impact of the hepatocyte growth factor receptor (MET) during cancer development, cancer growth, and cancer treatment is crucial to further improve biomarker development and cancer treatment options for patients' benefit. This reprint gives a snapshot of the current understanding of MET in lung and gastric cancer, describes promising new therapeutics, and emphasizes some of the challenges associated with their use
    Note: English
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  • 13
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592046 , 9783036592053
    Language: Undetermined
    Pages: 1 Online-Ressource (172 p.)
    Keywords: Medicine
    Abstract: This Special Issue on Atopic Dermatitis focuses on novel insights into the pathogenesis of the immunological components of the disorder and the impaired epidermal barrier properties. It also explores the efficacy and safety of breakthrough therapies with topical agents and systemic therapies, such as monoclonals and JAK inhibitors. The aim of this Special Issue is also to present the expected future forefront of research and the treatment options that are expected to be available in the next few years
    Note: English
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  • 14
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590882 , 9783036590899
    Language: Undetermined
    Pages: 1 Online-Ressource (206 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Fatty acids (FAs) are considered very important biomolecules because they have been used as trophic biomarkers in the marine food chain analysis of several ecological niches. They are compounds universally present in all organisms and play very important biological roles, such as acting as building blocks in biological membranes and signaling molecules. A great number of different fatty acids (saturated, mono- and di-unsaturated, branched, halogenated, hydroxylated, and methoxylated), as well as the major polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, occur in marine organisms. In addition, marine organisms are a rich source of metabolites with unusual structures that often exhibit interesting pharmacological properties. Moreover, it is worth emphasizing that the nutritional value of fish and marine invertebrates directly depends on their lipid composition and, in particular, their fatty acid profile, and this represents the basis of the trade of most international marine products. For this Special Issue, we invited academic and industry scientists to submit reviews and original research articles focusing on the chemistry, biological roles, and bioactivities of fatty acids from marine organisms
    Note: English
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  • 15
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594545 , 9783036594552
    Language: Undetermined
    Pages: 1 Online-Ressource (370 p.)
    Keywords: Medicine
    Abstract: Physical activity and exercise testing are two key points in sports medicine. Sports medicine is a field of medicine concerned with the prevention and treatment of injuries and disorders that are related to participation in sports. Clinical assessment in sports medicine can solve many questions about diagnosis, treatment, and prognosis related to health in sports. Physical activity could be defined as any bodily movement produced by skeletal muscles that requires energy expenditure. Physical activity refers to all movement including during leisure time, for transport to get to and from places, or as part of a person’s work. Both moderate- and vigorous-intensity physical activity improve health. Regular physical activity is proven to help prevent and manage noncommunicable diseases such as heart disease, stroke, diabetes, and several cancers. It also helps prevent hypertension, maintain a healthy body weight, and can improve mental health, quality of life, and well-being. Exercise could be defined as a subset of physical activity that is planned, structured, and repetitive and has as a final or an intermediate objective, such as the improvement or maintenance of physical fitness. Gait and posture analysis, clinical assessment, biomechanical analysis, reliability and repeatability research, force platform and electromyography analysis are key in order to improve our knowledge in this area
    Note: English
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  • 16
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593586 , 9783036593593
    Language: Undetermined
    Pages: 1 Online-Ressource (256 p.)
    Keywords: Medicine
    Abstract: Elderly frailty represents the poor resolution of homeostasis following stress and an increased risk of adverse outcomes, including falls, delirium and disability. This reprint is focused on the diagnosis and treatment of fractures and orthopedic diseases among elderly people. In particular, this concerns medical, orthopaedics and rehabilitative factors. This reprint includes original articles, narrative or systematic reviews and meta-analysis, aiming to provide readers with the correct approach to these pathologies
    Note: English
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  • 17
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592978 , 9783036592961
    Language: Undetermined
    Pages: 1 Online-Ressource (156 p.)
    Keywords: Medicine
    Abstract: Lower genital tract diseases include vulvovaginal and HPV-related diseases, ranging from benign to pre-neoplastic and neoplastic lesions. Nowadays, there has been increasing interest in innovative methods to diagnose and prevent cervical cancer through HPV primary screening programs. However, other lower genital tract diseases are unrelated to HPV infection; hence, cytology, colposcopy, and sonography might play a crucial role in assessment and management. This Special Issue aims to address current and emerging issues in the field of the diagnosis, assessment, staging, and management of HPV-related and not-related pathology of the lower female anogenital tract. These may include new advancements in HPV testing and laboratory biomarkers, investigations on the actual role of cytology and implementation of diagnostic tools to implement differential diagnosis, and the current clinical management of lower genital tract diseases
    Note: English
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  • 18
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593180 , 9783036593197
    Language: Undetermined
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Medicine
    Abstract: In recent years, there have been remarkable advances in the diagnosis and treatment of biliary tract diseases. Among them, the advanced endoscopic treatments and anti-tumor therapies for biliary tract cancer are outstanding. This reprint contains the latest research articles and review articles focusing on the diagnosis and treatment of biliary tract diseases using endoscopic retrograde cholangiopancreatography (ERCP) or endoscopic ultrasounds (EUSs) for biliary stricture, cholecystitis, cholangitis, ampullary tumors, and chemotherapy for biliary tract cancer
    Note: English
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  • 19
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592725 , 9783036592732
    Language: Undetermined
    Pages: 1 Online-Ressource (178 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: This Special Issue delves deeply into the intricate distinctions between acute and chronic pain. Crucially, chronic pain is more than a mere by-product of sensory input; it entails the activation of a complex brain network intertwined with biopsychosocial factors. As such, its management emerges as a formidable clinical challenge. Within the scope of this Special Issue, focused attention is given to postoperative pain (POP) and chronic postsurgical pain (CPSP). POP, characterized by its predictability, intensity, and short duration, contrasts starkly with the potentially persistent and troublesome nature of CPSP, which can endure for over three months if not adequately addressed. The prevention of CPSP takes on paramount importance, with regional anesthesia techniques emerging as promising tools for intervention. The pivotal role of multimodal analgesia and combined therapeutic strategies is underscored. The Special Issue also delves into the intriguing realm of gender differences in pain perception, advocating for further research to illuminate these disparities. Risk factors contributing to the development of chronic pain following surgery are meticulously identified. Lastly, this Special Issue explores the potential of new technologies in the field of telemedicine and artificial intelligence to optimize care delivery, opening new avenues for enhanced patient outcomes and treatment strategies
    Note: English
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  • 20
    ISBN: 9783036592954 , 9783036592947
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Medicine
    Abstract: This Special Issue aimed to cover a diverse scope of topics, from diagnostics to the management of temporomandibular disorders and myofascial pain, with a special focus on innovations in those areas. Intense research progress in the subject as well as technological development, access to knowledge, and novel digital tools allow developing more precise, reproducible, and dedicated diagnostic and therapeutic protocols
    Note: English
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  • 21
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594415 , 9783036594408
    Language: Undetermined
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Medicine ; Oncology
    Abstract: The Special Issue, titled “Therapeutic Landscapes in Colorectal Carcinoma”, illustrates a stimulating collection of articles written by international specialists that can promote discussions and ideas among colleagues working on CRC. It provides us with a deeper insight into the latest advances involving knowledge on CRC from scientific, translational, and clinical points of view. Through this Special Issue, our main purpose was to shed light on some state-of-the-art research on CRC. Here, the reader will find papers on prognostic factors as well as responses to neoadjuvant and adjuvant CRC treatments. Finally, we discuss the research trends and hotspots for CRC therapies that emerged during the COVID-19 pandemic, such as the potential achievement of a transition from CRC clinical research to precision medicine, together with a special emphasis given to new single-cell-based techniques. We hope that it can encourage translational and interdisciplinary collaborations, leading to a definitive understanding of strategies to overcome and inhibit CRC progression and metastasis
    Note: English
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594187 , 9783036594194
    Language: Undetermined
    Pages: 1 Online-Ressource (322 p.)
    Keywords: Medicine
    Abstract: The huge prevalence of type 2 diabetes is a leading human and economic concern worldwide. The diagnosis code of type 2 diabetes includes multiple clinical phenotypes showing different degrees of obesity, fat distribution patterns, types of dyslipidemia, and characteristics of insulin resistance syndrome. In addition, subjects with type 2 diabetes could develop different clinical trajectories, with age being a critical factor in progression. The chronic complications of type 2 diabetes are a major cause of mortality and disability, and are ranked in the top places in western countries’ scores. The pathophysiological heterogeneity of type 2 diabetes is not captured by the current classifications and guidelines. The potential for diabetes progression and complications developing is different depending on the type 2 diabetes cluster, which is mostly regardless of the degree of glycemic control. However, the impact on quality and life expectancy with the current therapeutic approach is not always the same for every individual. Clinical research is the key to reducing the burden of diabetes. New basic, digital, and clinical approaches are obtaining useful knowledge and designing more individualized interventions to prevent, track, and treat diabetic complications. This Special Issue is a clear reflection of this methodological evolution
    Note: English
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  • 23
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591803 , 9783036591810
    Language: Undetermined
    Pages: 1 Online-Ressource (114 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: This reprint discussed the role of retinal and optic nerve imaging in addition to its application in ophthalmic diseases and clinical medicine. It includes some high-quality articles containing original research results as well as review articles of exceptional merit
    Note: English
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  • 24
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593302 , 9783036593319
    Language: Undetermined
    Pages: 1 Online-Ressource (192 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: The evaluation of vascular stiffness is becoming increasingly important in cardiovascular research to determine the properties of the arterial tree and clinically assesspatients. Current research addresses and debates some unresolved technical and methodological issues with measuring arterial stiffness, with the purpose of making it more reliable and clinically suitable. This Special Issue focuses on new methodological advances in vascular stiffness, as well as preclinical and clinical applications. A privileged space is reserved for new data and targeted reviews of the application of arterial stiffness and early vascular ageing measures regarding problems such as the stratification of risk of special populations and specific diseases
    Note: English
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  • 25
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594880 , 9783036594897
    Language: Undetermined
    Pages: 1 Online-Ressource (166 p.)
    Keywords: Medicine
    Abstract: Glaucoma is a major cause of blindness that can be prevented if detected and treated in the early stages of the disease. This reprint includes original research studies and reviews that focus on strategies to help identify and treat patients with glaucoma more effectively, improve their treatment adherence, review the potential impact of psychopharmacological therapy on intraocular pressure, and increase knowledge of potential treatment targets for neuroprotection
    Note: English
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  • 26
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591094 , 9783036591087
    Language: Undetermined
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: In this Special Issue, our aim was to collect studies on clinical pharmacology and pharmacy of antimicrobial agents from both human and veterinary medicine as the complex problem of AMR requires actions taken within the One Health approach that involve both fields. Studies covered here are about new or optimized usage of already authorized antimicrobials, as well as discoveries about new agents, new combinations of drugs, and drug repositioning. Pharmacodynamic, pharmacokinetic, and toxicological aspects of individual and combinational drug use are areas covered in this Special Issue
    Note: English
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  • 27
    ISBN: 9783036593906 , 9783036593913
    Language: Undetermined
    Pages: 1 Online-Ressource (148 p.)
    Keywords: Medicine
    Abstract: With increasing speed, new diagnostic and therapeutic approaches for facial nerve disorders are being published. Many of them have improved decision-making, treatment, and the rehabilitation of patients. Unfortunately, there is often a lack of high-quality studies that prove long-term effects or identify subgroups that are of particular benefit. Even a reliable characterization of patients with facial nerve disabilities is often complicated. Therefore, evidence-based management remains challenging. With this Special Issue on the topic of “Evidence-Based Diagnosis and Management of Facial Nerve Disorders”, we have brought together experts from various fields, including speech pathology, plastic surgery, otolaryngology, neurology, and physical therapy, to present the latest developments in relation to facial nerve disorders and to present a great variety of topics to our readership. We can see that the topic of facial nerve palsy offers a vast and dynamic spectrum of developments, and hope that the research presented in this Special Issue shows the importance of a multidisciplinary approach. We hope it will not only enhance our knowledge of this condition, but also ultimately improve patient outcomes and their quality of life to some extent
    Note: English
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  • 28
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591612 , 9783036591605
    Language: Undetermined
    Pages: 1 Online-Ressource (128 p.)
    Keywords: Medicine
    Abstract: This collection brings together basic and clinical research papers that cover different topics in audiology but have one thing in common: the translational approach. The research in this collection demonstrates how exciting and interesting translational audiology can be. This collection aims to stimulate interest and encourage more studies of this type
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  • 29
    ISBN: 9783036592640 , 9783036592657
    Language: Undetermined
    Pages: 1 Online-Ressource (270 p.)
    Keywords: Medicine
    Abstract: Otorhinolaryngology and head and neck specialists worldwide face an increasing incidence and prevalence of various pathologies, some of the cases neglecting the evolution of their condition during the period of COVID-19 pandemics, thus aggravating their evolution. This Special Issue contains reviews and selected rare case series to update the protocols of ENT and allied specialists worldwide. The aim was to present an interdisciplinary point of view of the numerous branches of pathology that form the otorhinolaryngology specialty
    Note: English
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  • 30
    ISBN: 9783036592442 , 9783036592459
    Language: Undetermined
    Pages: 1 Online-Ressource (226 p.)
    Keywords: Medicine
    Abstract: The growing improvement of medical sciences in the diagnosis and treatment of head and neck oncological diseases has produced a significant increase in the life expectancy of affected patients. it is therefore necessary to direct new energies towards understanding and protecting the quality of life of cancer patients. This reprint presents the fruit of the research protocols of numerous groups around the world on the topics of life expectancy and quality of life of patients suffering from head and neck cancer
    Note: English
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  • 31
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587974 , 9783036587967
    Language: Undetermined
    Pages: 1 Online-Ressource (330 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Research in ophthalmic drug delivery has developed significant advances in the last few years, and efforts have been made to develop more effective topical formulations to increase drug bioavailability, efficiency, and safety. Drug delivery to the posterior segment of the eye remains a great challenge in the pharmaceutical industry due to the complexity and particularity of the eye's anatomy and physiology. Some advances have been made with the purpose of maintaining constant drug levels in the site of action. The anatomical ocular barriers have a great impact on drug pharmacokinetics and, subsequently, on the pharmacological effect.Despite the increasing interest in efficiently reaching the posterior segment of the eye with reduced adverse effects, there is still a need to expand the knowledge of ocular pharmacokinetics that allow the development of safer and more innovative drug delivery systems. These novel approaches may greatly improve the lives of patients with ocular pathologies
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  • 32
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592480 , 9783036592497
    Language: Undetermined
    Pages: 1 Online-Ressource (164 p.)
    Keywords: Medicine
    Abstract: As Guest Editors, we are very delighted to see the reprint of our Special Issue, “Head and Neck Surgery: Clinical Updates and Perspectives", which is published in the Otolaryngology section of the Journal of Clinical Medicine. These papers are the joint effort of many excellent colleagues who have devoted their lives and careers to the exciting field of Otorhinolaryngology. As both clinicians and surgeons, we are actively advancing the diagnosis and management of the myriad of conditions affecting the head and neck region. Unprecedented discoveries in the field of genetics and molecular biology are always integrated with sound knowledge of the intricate anatomy of our discipline, while technological advancements now permit us to provide tailored and minimally invasive treatments for our patients. We wish to thank all the authors who contributed to this publication and we hope you enjoy reading it
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  • 33
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036577708 , 9783036577715
    Language: Undetermined
    Pages: 1 Online-Ressource (152 p.)
    Keywords: Medicine
    Abstract: Studies on global human genomic variation have shown important population-based differences in allele frequencies of common single-nucleotide polymorphisms (SNPs) that influence the expression of genes related to nutrition and, secondarily, chronic disease. Some SNP sites have known functions or associations with diseases or other phenotype characteristics, including nutritional deficiencies and metabolism dietary components. There are many components of human diets that, when combined with the impact of diverse genetics on the metabolism of certain nutrients, have the capacity to give rise to harmful diet–gene interactions. This situation has the potential capacity to modify molecular phenotypes and clinical phenotypes, including human disease. Obesity, diabetes mellitus, chronobiology, osteoporosis, cancer, and many other diseases are fields of potential investigation in this topic area. This Special Issue will include manuscripts that focus on the complex relationship between gene polymorphisms and nutrition across all physiological and chronic diseases
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  • 34
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591766 , 9783036591773
    Language: Undetermined
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: The field of orthopedic trauma has always been a discipline cahacterized by rapid innovation and creative evolution. We see evolution in every facet of orthopedic surgery, ranging from the transformation of the understanding of implant design and biomechanics to the understanding and monitoring of fracture healing and the management of complications. This Reprint includes many articles discussing topics, such as distal radius fractures, hip fractures, osteoarthritis, ankle fractures, acetabular fractures, and anterior cruciate ligament reconstruction
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  • 35
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587790 , 9783036587783
    Language: Undetermined
    Pages: 1 Online-Ressource (182 p.)
    Keywords: Medicine
    Abstract: This Special Issue dives into the evolving realm of sports science by exploring innovative methods to enhance athletes' motor skills and performance. It showcases research studies aiming to discover validated strategies, cutting-edge approaches, and the intricate interplay of factors that shape athletic excellence. From training methodologies to technological advancements, this collection of empirical investigations and reviews offers valuable insights for both trainers and scientists. We invite readers to join us in uncovering the science behind peak athletic achievement
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  • 36
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591100 , 9783036591117
    Language: Undetermined
    Pages: 1 Online-Ressource (184 p.)
    Keywords: Medicine
    Abstract: Vestibular medicine relates to the assessment, diagnosis, and treatment of patients with dizziness and vertigo. In all these fields, there has been an enormous increase in research during recent years. This edition includes a discussion on the epidemiology of dizziness, the role of genetics in the development of vestibulopathy, diagnostic approaches, and interventions for patients with dizziness and vertigo: medical treatment, surgery, and vestibular rehabilitation
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  • 37
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589022 , 9783036589039
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Aortic aneurysm is a multifactorial progressive life-threatening disease. Recent surgical treatment and endovascular repair help to prevent aortic ruptures. However, there are no effective pharmacological treatments to limit aneurysm growth. This Special issue, entitled “Aortic Aneurysms: Vascular Remodeling and Repair", represents a collection of articles from innovative scientists that focuses on the recent advances in diagnostics, pathogenesis and therapies of aneurysms. This reprint includes a systematic review and nine original papers on clinical imaging, prognostic methods, genome-wide screening, novel cell signaling pathways and drug targets. We hope that readers will gain a deeper understanding of this topic and enjoy reading this reprint
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  • 38
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589657 , 9783036589640
    Language: Undetermined
    Pages: 1 Online-Ressource (286 p.)
    Keywords: Medicine
    Abstract: Chronic obstructive pulmonary disease (COPD) is a disorder characterized by airflow limitation and is one of the major causes of mortality and morbidity across the globe. Although several guidelines have been published over the past three decades, they were generated in response to the fact that COPD is a major cause of mortality and morbidity and remains an important social problem. In the 20th century, forced expiratory volume in one second (FEV1) was the single most important measure in patients with COPD from discriminative, evaluative, and predictive standpoints. We found that dyspnea is a better mortality predictor than FEV1 in 2002 and exercise capacity in 2003. Subsequently, it has become apparent that physical activity is more predictive of mortality. Furthermore, we have recently developed the tendency to use the reduction of the future risk of exacerbation as the endpoint of relatively large-scale clinical trials rather than the improvement of FEV1. Many researchers have continued to seek better outcome markers and have also discussed what should be used as primary or secondary endpoints in clinical trials in subjects with COPD. We have undoubtedly made great progress but still have a lot of work to do for the best interests of patients
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  • 39
    Language: Undetermined
    Pages: 1 Online-Ressource
    Keywords: Medicine
    Abstract: The war in Syria has lasted for many years and continues to cast a dark shadow over its people, including healthcare workers caring for those injured and in distress. During the war, healthcare workers have been exposed to unprecedented challenges, becoming targets of bombing, killing, siege, arrest, and torture. Moreover, healthcare workers continue to experience difficult situations that require them to make decisions with no clear or easy moral choice. The present study aimed to understand the experiences of healthcare workers and the difficulties and challenges that hinder applying existing ethical frameworks and codes for disasters within Syria’s context of revolution and war. Qualitative analysis of interviews led to classification of the ethical challenges experienced by healthcare workers into four groups: the risks from providing care; stewardship of resources and work challenges; corruption and organizational pressure; and psychological, emotional, and social stress. The study also showed that both Syrian healthcare workers and the developers of ethical frameworks adopt many similar values and principles. Yet, the participants adopted several unique moral values not identified in ethical frameworks as a result of navigating their professional duties under the circumstances of the Syrian war. At last, recognizing the challenges and precarious tasks healthcare workers cope with during wars and other similar disasters could help volunteers, medical personnel, and humanitarian organizations deciding to work in Syria better understand the specific context and obstacles for ethical decision-making. Moreover, attracting attention for and support of Syrian healthcare workers locally and globally presents a long-lasting benefit
    Note: English
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  • 40
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    Nijmegen : Radboud University Press
    Language: Undetermined
    Pages: 1 Online-Ressource (194 p.)
    Keywords: Anthropology ; Health economics ; Health systems & services ; Health & personal development ; Medicine ; Public health & preventive medicine
    Abstract: In his professional journey, travelling through an upcoming field of surgery with apparently unlimited possibilities, Kees van Laarhoven witnessed major milestones and breakthroughs. Already as a medical student, he was amazed by surgical courage. During residency, he experienced hard work, diligence and perseverance of surgical professionals. Today as a surgeon with over 25 years of clinical experience he now looks at pieces of art in surgery with professionals compassionately bringing hope to patients.But he also sees inconvenient truths in our healthcare system, with patients evolving from one predictable and preventable disease to the next and with professionals following disease trends rather than applying their knowledge to redirect disease into health. The modern disease-oriented care system becomes undesirable and unsustainable. And there are more inconvenient truths that have progressed rather than diminished in time. Healthcare is not easily accessible to the major half of the global population and for those who have access, with a growing global population, healthcare may become unaffordable in the future. Moreover, from an environmental perspective, both human and planetary health are compromised and ask for a ‘One Health’ approach. Being fascinated by the questions of how and why did this all happen, Kees van Laarhoven took up a scientific survey to comprehend and learn how things still can be changed. He found that clear solutions are there! Please join him on his journey
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  • 41
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589381 , 9783036589398
    Language: Undetermined
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Medicine ; Neurosciences
    Abstract: In this Special Issue, we have compiled data and opinions from leading scientists to demonstrate the recent advances in the study of function and dysfunction of synucleins. These proteins are involved in multiple normal and pathological molecular processes and consequently have various effects on cell biology of the nervous system. Three members of the synuclein family share many structural properties and have an overlapping pattern of expression and intracellular distribution in the developing and adult nervous system, which point to functional redundancy within the family. However, each synuclein has its own functions which are not shared with the two other family members, and there are certain cellular mechanisms and pathways in which these functions could be antagonistic rather than synergistic
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  • 42
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036592503 , 9783036592510
    Language: Undetermined
    Pages: 1 Online-Ressource (254 p.)
    Keywords: Medicine
    Abstract: The advent of optical coherence tomography (OCT) has arrived in an era in which the in vivo, cross-sectional imaging of both the retina and choroid is possible. Infra-red rays of light are used to image the chorioretinal layers with an image resolution reaching 10-15 microns. During the last three decades, OCT technology has undergone several improvements, such as spectral domain OCT (SD-OCT), swept source OCT (SS-OCT), enhanced depth imaging (EDI-OCT), wide field OCT, intraoperative OCT, OCT angiography (OCTA), and adaptive optics OCT. These enhancements help in both the qualitative and quantitative analysis of chorioretinal parameters in pathologies such as macular edema, neurosensory detachment, retinoschisis, macular holes, epiretinal membranes, and choroidal tumors. An added advantage is the role of OCT in the evaluation of optic disc disorders, including optic neuritis and glaucoma, via the quantitative analysis of the retinal nerve fiber layer. Moreover, OCT being non-invasive provides an opportunity for serial imaging during follow-up visits. Overall, OCT imaging provides tissue details, closely mimicking the histopathology, and is an invaluable asset in the armamentarium of retina physicians. This special issue includes applications of OCT in various chorioretinal disorders
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  • 43
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590530 , 9783036590523
    Language: Undetermined
    Pages: 1 Online-Ressource (306 p.)
    Keywords: Medicine ; Physiology
    Abstract: Several factors have been identified as interfering with the success, rehabilitation, and fitness of athletes from childhood to adulthood, as well as in para-sport, and special populations, according to research. The performance and health of this population are affected by the relationships between stress, maturation, training load, and recovery. Environmental approaches aim to increase efficiency and physiological adaptations in this sense. In various situations and conditions, however, this stimulus–performance–adaptation relationship varies.As a result, we received contributions related (but not limited) to the following topics: training load monitoring; stress and physiological responses during exercise or sports; recovery process after exercise; changes after stress and/or training load; physiology of training in health and sports performance
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  • 44
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594484 , 9783036594491
    Language: Undetermined
    Pages: 1 Online-Ressource (288 p.)
    Keywords: Medicine ; Epidemiology & medical statistics
    Abstract: Viruses in the Parvoviridae family constitutes a most diverse and intriguing field of research. Parvoviruses have a long evolutionary history and, beneath an apparent simplicity and uniformity, can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. In addition to interest in the study of basic virology, the translational implications of research on parvoviruses are relevant since many viruses are important human and veterinary pathogens, while other viruses can be engineered as tools for oncolytic therapy or as sophisticated gene delivery vectors. Exploring the diversity and the inherent complexity in the biology of these apparently simple viruses is an ongoing commitment for the scientific community to address. This Special Issue entitled ‘Advances in Parvovirus Research 2022’ continued the series dedicated to research on viruses belonging to the Parvoviridae family and collected the latest contributions in the field of parvovirus research
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  • 45
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593043 , 9783036593050
    Language: Undetermined
    Pages: 1 Online-Ressource (198 p.)
    Keywords: Medicine
    Abstract: This reprint "Clinical Features of COVID-19 in Elderly Patients" is a crucial resource dedicated to the medical challenges posed by the pandemic, with a specific focus on its impact on elderly people. Given their vulnerability, understanding the clinical aspects of COVID-19 in this demographic is paramount. This reprint compiles a wide array of studies and current knowledge tailored to address the unique challenges faced by elderly people during the pandemic. It surpasses literature reviews, offering critical analysis and in-depth discussions. Its primary goal is to encourage critical analyses and discussions about the clinical characteristics of COVID-19 in elderly people. Targeted towards medical professionals, researchers, and healthcare practitioners, it aids in the development of tailored treatment approaches and care protocols. As the COVID-19 pandemic persists, this reprint remains essential for those dedicated to combating the virus, enhancing elderly patients’ care, and promoting public health
    Note: English
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  • 46
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590417 , 9783036590400
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: The reprint is a collection of original articles and reviews in the field of modern drug delivery systems and strategies for efficient drug transport across various biological barriers, including the blood–brain barrier, mucosal and endothelial barriers, and cell membranes
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  • 47
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593203 , 9783036593210
    Language: Undetermined
    Pages: 1 Online-Ressource (330 p.)
    Keywords: Medicine
    Abstract: Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, accounting for 〉80% of primary liver cancers worldwide. The diagnosis of HCC, relying solely on noninvasive criteria, is currently under debate due to the need for molecular information that necessitates tissue biopsies, while therapy is provided in accordance with tumor stages and the anticipated advantages of major interventions, following the Barcelona Clinic Liver Cancer (BCLC) staging system. Principally, resection, transplantation and local ablation are most commonly performed in patients with early-stage HCC tumors, while TACE and systemic therapy are, respectively, the preferred treatment options for intermediate- and advanced-stage tumors. However, the HCC tumor immune microenvironment (TME) affects the response to current anti-PD-1/PD-L1 immunotherapies. Therefore, an enhanced understanding of the immunobiology of TME is essential for the development of predictive biomarkers of patient stratification and strategies of drug combinations to improve therapeutic efficacy, especially for patients with tumors that are unresponsive to anti-PD-1/PD-L1 therapy. Taking into account the health burden of HCC worldwide, with this Special Issue, we aim to enhance our knowledge of innovative diagnostic and prognostic methods and to discuss experimentation with different novel treatment modalities, believed to be of the utmost priority to progress in our seemingly never-ending fight against hepatocellular cancer
    Note: English
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  • 48
    ISBN: 9783036595504 , 9783036595511
    Language: Undetermined
    Pages: 1 Online-Ressource (204 p.)
    Keywords: Medicine
    Abstract: This Special Issue includes 12 articles, consisting of original research, narrative reviews, systematic reviews, and an editorial regarding the roles of dietary and lifestyle factors in the prevention and mangement of noncommunicable diseases. Studies in this Special Issue cover a range of topics including dietary patterns and diseases risk and prevention, the association of lifestyle factors and disease risk, the role of vitamin D and solar radiation in health and pregnancy, and urbanization in modifying risk of adverse health outcomes for various noncommunicable diseases
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  • 49
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594583 , 9783036594590
    Language: Undetermined
    Pages: 1 Online-Ressource (464 p.)
    Keywords: Medicine
    Abstract: This reprint is a compilation of cutting-edge knowledge in the field of bariatric surgery. It addresses the growing obesity epidemic and provides in-depth insights into the latest innovations in bariatric surgery and its future prospects. The content of the work includes a comprehensive review of modern surgical techniques. Additionally, it explores key aspects of preoperative assessment, postoperative follow-up, and the management of potential complications. The reprint highlights the benefits of bariatric surgery in improving the health and quality of life of morbidly obese patients. The reprint also addresses emerging trends in research and technology, such as robotic surgery and gene therapy, which hold the promise of further revolutionizing the field
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  • 50
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594392 , 9783036594385
    Language: Undetermined
    Pages: 1 Online-Ressource (234 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: The Special Issue titled “Recent Advances in Long-Acting Drug Delivery and Formulations” encompasses versatile and innovative research domains of oral, ocular, brain, and topical delivery systems and chemical approaches (e.g., prodrugs), highlighting the progress made in identifying excipients (e.g., basic amino acids to ameliorate gastric side effects of non-steroidal anti-inflammatory drugs (NSAIDs)), polymers, and molecular targets to achieve more effective sustained release systems and safer medicine. In this Special Issue, 78 authors have contributed, with eleven original research articles spanning five continents (Asia, Europe, Africa, North America, and Australasia) providing important insights into the pharmaceutical sciences
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  • 51
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593869 , 9783036593876
    Language: Undetermined
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Medicine
    Abstract: Gastrointestinal (GI) malignancies represent a diverse spectrum of cancers with notable global incidence and prevalence. The comprehensive care of individuals affected by these malignancies is a multifaceted endeavor involving the collaboration of various medical disciplines. The nonspecific clinical manifestations of GI cancers often present a formidable diagnostic challenge to primary care providers, resulting in diagnostic delays. Subsequently, the treatment regimens, once initiated, are often demanding and prolonged, and profoundly impact the patients' overall quality of life. Given the intricate involvement of the digestive system, nutritional concerns are pervasive among these patients, influencing both their quality of life and survival. Despite these considerable challenges, the evolving landscape of treatment modalities has yielded improved outcomes, enabling a greater number of patients to achieve remission or extended survival. It is now imperative that we delve deeper into understanding the unique needs of this patient population and refine the care delivery pathways through enhanced diagnostic approaches, treatment strategies, and holistic support, and ultimately enhance the overall value of care provided to individuals afflicted by GI malignancies
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  • 52
    ISBN: 9783036595320 , 9783036595337
    Language: Undetermined
    Pages: 1 Online-Ressource (670 p.)
    Keywords: Medicine
    Abstract: Sensors used to diagnose, monitor or treat diseases in the medical domain are known as medical sensors. There are several types of medical sensors that can be utilized for various applications, such as temperature probes, force sensors, pressure sensors, oximeters, electrocardiogram sensors that measure the electrical activity of the heart, heart rate sensors, electroencephalogram sensors that measure the electrical activity of the brain, electromyogram sensors that record electrical activity produced by skeletal muscles, and respiration rate sensors that count how many times the chest rises in a minute. The output of these sensors used to be interpreted by humans, which was time consuming and tedious; however, such interpretations became easy with advances in artificial intelligence (AI) techniques and the integration of the sensor outputs into computer-aided diagnostic (CAD) systems. This reprint presents some of the state-of-the-art AI approaches that are used to diagnose different diseases and disorders based on the data collected from different medical sensors. The ultimate goal is to develop comprehensive and automated computer-aided diagnosis by focusing on the different machine learning algorithms that can be used for this purpose as well as novel applications in the medical field
    Note: English
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  • 53
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594439 , 9783036594422
    Language: Undetermined
    Pages: 1 Online-Ressource (282 p.)
    Keywords: Medicine
    Abstract: Thanks to the breast cancer research of recent decades, effective methods and strategies have been established, allowing the mortality rates of breast cancer patients to decrease more and more. However, we still face many challenges. The role of certain biomarkers or mutations is still not clear for treatment and surveillance. Novel drugs are often associated with a different spectrum of adverse events than that seen for conventional therapies, accordingly having an impact on patients’ compliance behaviors. In breast cancer surgery, in some cases, the question remains whether to escalate or deescalate. Additionally, with regard to diagnostics, in a digitalized world, home-based tools and therapy monitoring options are of high importance, especially under the tough conditions and supply problems seen during the COVID-19 pandemic.This Special Issue gathers original research articles and reviews demonstrating therapeutic challenges, current research strategies, and novel diagnostics in breast cancer
    Note: English
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  • 54
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594774 , 9783036594767
    Language: Undetermined
    Pages: 1 Online-Ressource (338 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Terrestrial and marine environments are inexhaustible sources of compounds and active extracts which have been employed in medicine since ancient times. The aim of this reprint is to collect new approaches around compounds and extracts isolated from natural products and their biological activity, with a focus on anti-inflammatory pathways. Thus, this reprint compiles full original papers and reviews articles published during 2023 in a Special Issue of Life, titled “Inflammation and Natural products”. The publications within this reprint are focused on secondary metabolites of plants demonstrating significant antioxidants and anti-inflammatory properties, among others, and clinical relevance in various pathological conditions. It also includes reviews that focus on natural therapies for topics such as arthritis, lung diseases, neuroprotection, skin photoprotection, and the impact of gender in the use of medicinal plants in relation to vascular diseases. The reprint of this Special Issue will serve as a reference text for researchers and academics, as well as those studying natural products and their pharmacological activities
    Note: English
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  • 55
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036588445 , 9783036588452
    Language: Undetermined
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: With the aging of the population, the incidence rate and number of elderly nervous system diseases have increased sharply. This event has brought huge problems to society. Despite significant efforts being made to explore new treatment options and drugs, the results have been limited. The reason may be due to people's incomplete understanding of the pathogenesis of these age-related diseases. Iron is the most abundant trace element in the human body and is essential for normal life activities. Previous studies have shown that brain iron levels increase with age. The abnormal increase in brain iron levels is closely related to age-related neurological diseases. The disruption of the redox balance may be an important mechanism for the occurrence of neurological diseases caused by brain iron abnormalities. This Special Issue mainly highlights and discusses the latest research progress related to the regulation of brain iron metabolism, redox balance, and the pathogenesis of neurological diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), cerebral ischemia, cancer and maintenance of cellular stemness. The molecular mechanisms of iron-misregulation-induced redox imbalance in disease pathogenesis were analyzed. On this basis, further discussions were conducted on potential therapeutic targets for regulating iron metabolism to achieve effective intervention in elderly neurological diseases
    Note: English
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  • 56
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594507 , 9783036594514
    Language: Undetermined
    Pages: 1 Online-Ressource (180 p.)
    Keywords: Medicine
    Abstract: This reprint focuses on the most recent advances in PET/CT imaging within the field of oncology. These innovations include studies on novel or experimental tracers, such as [18F]FES for the imaging of advanced breast cancer and [68Ga]Ga-Nitroimidazole for visualizing hypoxic tumour components; research on new radiopharmaceuticals represents, in fact, one the most important study fields of PET research. Advanced image analysis, such as radiomics, is also featured in this reprint; this method has been applied to both traditional nuclear medicine clinical issues, such as thyroid nodules, as well as in the setting of new therapeutic approaches, such as CAR-T cell therapy. Finally, the theranostic implications of PET radiotracers and the diagnostic processes of rare tumours are explored in this reprint
    Note: English
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  • 57
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590240 , 9783036590257
    Language: Undetermined
    Pages: 1 Online-Ressource (456 p.)
    Keywords: Medicine ; Oncology
    Abstract: Childhood cancer or pediatric cancer is one of the leading causes of death among children. Treatment strategies for pediatric cancers include chemotherapy, surgery, radiation, and stem cell transplantation. These therapeutic regimens are well known to develop highly toxic and long-lasting side-effects including secondary cancers in the future lifespan of pediatric patients. Despite these intensive therapeutic regimens, cancer may still relapse as refractory and metastatic cancer. Therefore, further understanding the causes of different pediatric cancers, mechanisms of drug-resistance, and causes of relapse and metastasis is required for developing and advancing less toxic and more effective therapeutic strategies for pediatric cancers. Recent advancements in immunotherapies and targeted therapeutic approaches using pharmacological inhibitors are one step in this direction.In this Special Issue of Cancers, authors contributed original research and review articles focusing on different aspects of pediatric cancer development, causes, maintenance, and therapeutic strategies. The collected articles in this Special Issue will further enhance our knowledge and understanding of pediatric cancers and drive the development of novel therapeutic strategies
    Note: English
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  • 58
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593623 , 9783036593630
    Language: Undetermined
    Pages: 1 Online-Ressource (152 p.)
    Keywords: Medicine
    Abstract: Children with pulmonology issues have always introduced challenges for pediatricians. This Special Issue provides a platform for researchers and clinicians to discuss the novel methods of functional assessment, new insights into exercise physiology, the effect of maturation and puberty on pulmonary parameters, the translational aspects of overweight and obesity, the evaluation of active rehabilitation in pediatric pulmonology, long-term and post-COVID-19 illnesses, the pediatric origin of adult diseases, etc
    Note: English
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  • 59
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590707 , 9783036590714
    Language: Undetermined
    Pages: 1 Online-Ressource (202 p.)
    Keywords: Medicine
    Abstract: Nurses represent the highest number of healthcare workers globally and have played a critical role in the COVID-19 pandemic. This reprint highlights the issues and challenges faced by nurses practicing in hospital and community settings during the COVID-19 pandemic. The manuscripts herein focus on nurses in various areas of practice, including nurse managers, highlighting the impact, experience, and reality of providing care during the crisis. Interventions and strategies to support practice environments and the mental health and wellbeing of the nursing workforce were identified. Evidence from these manuscripts shed light on how nurse leaders can provide relevant, coordinated, and consistent organizational and leadership support to better establish a safe and healthy work environment that protects and fosters the mental health and wellbeing of all nursing personnel. The pandemic exacerbated the already demanding quality of work environments for nurses, as well as their mental health and wellbeing, thereby inducing a global nursing shortage; therefore, improving these factors, which ultimately influence nurse retention, is critical. We trust that sharing the lived experiences of nurses during the COVID-19 pandemic can enable us to leverage their expertise in meeting the complex care needs of patients, including COVID-19 patients, while improving the care needed by nurses in their working environments, alongside preparing for future pandemic waves
    Note: English
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  • 60
    Online Resource
    Online Resource
    Prague : Karolinum Press
    ISBN: 9788024651965 , 9788024656922
    Language: Undetermined
    Pages: 1 Online-Ressource (83 p.)
    Keywords: Medicine
    Abstract: Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment
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  • 61
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036593661 , 9783036593678
    Language: Undetermined
    Pages: 1 Online-Ressource (462 p.)
    Keywords: Medicine
    Abstract: There are a variety of anesthetic management options during surgery, and these are constantly evolving. Both innovative and confirmatory research are important if the scientific community aims to develop and improve people’s quality of care. This reprint introduces new avenues and covers questions regarding innovative anesthetic techniques and unmet needs after surgery, paving the way for future improvements. It can be useful for both clinicians and clinical researchers, especially in light of the expansion of concepts like personalized care
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  • 62
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036587998 , 9783036587981
    Language: Undetermined
    Pages: 1 Online-Ressource (316 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Research in ophthalmic drug delivery has developed significant advances in the few last years, and efforts have been made to develop more effective topical formulations to increase drug bioavailability, efficiency, and safety. Drug delivery to the posterior segment of the eye remains a great challenge in the pharmaceutical industry due to the complexity and particularity of the eye's anatomy and physiology. Some advances have been made with the purpose of maintaining constant drug levels in the site of action. The anatomical ocular barriers have a great impact on drug pharmacokinetics and, subsequently, on the pharmacological effect.Despite the increasing interest in efficiently reaching the posterior segment of the eye with reduced adverse effects, there is still a need to expand the knowledge of ocular pharmacokinetics that allow the development of safer and more innovative drug delivery systems. These novel approaches may greatly improve the lives of patients with ocular pathologies
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  • 63
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589565 , 9783036589572
    Language: Undetermined
    Pages: 1 Online-Ressource (278 p.)
    Keywords: Medicine
    Abstract: The primary aim of this reprint is to describe the genomics of splenic lymphomas, hairy cell leukemia, Cutaneous lymphomas, plasma cell leukemia, MDS with deletion 5q, mastocytosis, hypodiploid acute lymphoblastic leukemia, CLL with complex karyotype and other rare hematologic cancers
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  • 64
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036589404 , 9783036589411
    Language: Undetermined
    Pages: 1 Online-Ressource (268 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Gastroenterology and hepatology are fields of research that have improved considerably in recent years in terms of clinical approach, diagnosis, and therapy. However, there is still much to be clarified and explored, and many questions remain unanswered. Therefore, basic research, including translational and clinical discoveries, supported by technological innovations such as artificial intelligence, will enable further steps toward better, more refined treatments for many digestive diseases. The challenge of modern medicine will therefore be to connect these two fields to ensure optimal patient management. Further innovations will help clinicians to improve clinical practice, establish new guidelines, and provide personalized treatment based on patient characteristics. The aim of this Special Issue is to highlight recent advances and future challenges in gastroenterology and hepatology
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  • 65
    ISBN: 9783036592763 , 9783036592770
    Language: Undetermined
    Pages: 1 Online-Ressource (246 p.)
    Keywords: Medicine
    Abstract: Chronic immune-mediated inflammatory diseases (IMIDs), usually accompanied by cardiovascular disease and neoplasias, are now prevailed worldwide. The limited efficacy of current therapeutics and a proportion of non-responders are linked to missing aspects in their pathophysiology at the molecular and cellular levels. High-throughput single- and multi-omics approaches and their combinations are expected to pinpoint the key players underlying IMIDs’ establishment and/or progression, thus suggesting potential therapeutic targets and biomarkers. This Reprint gathered 13 papers presenting recent relevant data related to the assessment of CVD risk in RA, tailored therapeutics in RA-interstitial lung disease, IgG4-related RA, and Sjögren’s syndrome, enabling early identification of PsA and improving outcomes in patients’ with psoriasis. Also, novel non-invasive biomarkers for endoscopic activity and mucosal healing in ulcerative colitis, IBD, and cell-death-associated inflammatory syndromes are proposed. Moreover, a certain subset of telocytes is suggested as the pilot governor of epithelial behavior in preneoplastic gastric lesions, a newer member of IL-1 family, as it is a critical partner in lung adenocarcinoma, while distinct transcriptomic signatures and pathway profiles in human melanocytes corresponding to different Staphylococcal superantigenic enterotoxins are possible targets for therapeutic intervention in cases of toxic shocks. Lastly, Tregs- and dendritic cell-based IMID biomarkers are recommended to enable at more efficient, personalized, and precise treatment strategies
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  • 66
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591667 , 9783036591674
    Language: Undetermined
    Pages: 1 Online-Ressource (188 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Bioactive metabolites from marine-derived fungi are known to be an important source of drug discoveries. Natural product scientists have explored various environments, such as the deep ocean and polar regions, as well as marine mangrove ecosystems, to discover unique fungi strains which could produce new bioactive structures. The aim of this Special Issue is to highlight the diversity of fungi derived from different marine environments, as well as their potential as producers of bioactive marine natural products. Innovative scientific results, as well as approaches and methodologies applied in marine natural product discovery areas, are encouraged. Studies on the biosynthesis and bioactivities of marine natural products are also welcome. For this Special Issue, we invited academic and industry scientists to submit reviews and original and conceptual research articles highlighting diversified marine fungi as a source of bioactive natural products
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  • 67
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591988 , 9783036591995
    Language: Undetermined
    Pages: 1 Online-Ressource (218 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: Sudden cardiac death (SCD) affects more than four million patients per year worldwide, and accounts for up to 50% of all cardiovascular deaths. Related to the improved treatment options for cardiovascular diseases during the past several decades (e.g., improved guideline adherence to pharmacotherapies, increasing supply with cardiac devices, and better revascularization strategies), the characteristics of patients presenting with SCD have significantly changed, making risk prediction for SCD even more complex. The present Special Issue reprint addresses the prognostic impact of patients’ characteristics (such as body mass index), airway and ventilation management in patients needing cardiopulmonary resuscitation, and the prognostic value of a targeted ambulance treatment quality improvement programme. Furthermore, the prognostic value of blood-derived biomarkers and cardiac pharmacotherapies for the prevention of SCD was investigated
    Note: English
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  • 68
    ISBN: 9783036590783 , 9783036590790
    Language: Undetermined
    Pages: 1 Online-Ressource (142 p.)
    Keywords: Medicine ; Cardiovascular medicine
    Abstract: Today, interventional treatment and clinical management of cardiac arrhythmias represent a continuous challenge. This is mainly due to the widening of indications for implantable electronic devices and for catheter ablation procedures as well as the continuous improvement of technologies and medical therapies. Despite international guidelines and worldwide consensus updates, evidence gaps persist at all points in the real-world setting. This Special Issue aims to provide a comprehensive overview of advances in the indications, diagnosis, and treatment of cardiac rhythm disturbances, with particular interest in the use of innovative techniques and technologies in interventional therapies
    Note: English
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  • 69
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036591940 , 9783036591957
    Language: Undetermined
    Pages: 1 Online-Ressource (394 p.)
    Keywords: Medicine
    Abstract: Nurses represent the highest number of healthcare workers globally and have played a critical role in the COVID-19 pandemic. This reprint highlights the issues and challenges faced by nurses practicing in hospital and community settings during the COVID-19 pandemic. The manuscripts herein focus on nurses in various areas of practice, including nurse managers, highlighting the impact, experience, and reality of providing care during the crisis. Interventions and strategies to support practice environments and the mental health and wellbeing of the nursing workforce were identified. Evidence from these manuscripts shed light on how nurse leaders can provide relevant, coordinated, and consistent organizational and leadership support to better establish a safe and healthy work environment that protects and fosters the mental health and wellbeing of all nursing personnel. The pandemic exacerbated the already demanding quality of work environments for nurses, as well as their mental health and wellbeing, thereby inducing a global nursing shortage; therefore, improving these factors, which ultimately influence nurse retention, is critical. We trust that sharing the lived experiences of nurses during the COVID-19 pandemic can enable us to leverage their expertise in meeting the complex care needs of patients, including COVID-19 patients, while improving the care needed by nurses in their working environments, alongside preparing for future pandemic waves
    Note: English
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  • 70
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036590868 , 9783036590875
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: The Special Issue “Bioactive Secondary Metabolites of Marine Fungi” gathered ten publications, including two reviews and eight research articles, about marine fungi, ranging from the isolation and structure elucidation of new natural products to the biosynthetic pathways of marine fungal metabolites
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  • 71
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036594323 , 9783036594330
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Though the number of infants born with heart disease each year is relatively small (approximately 1% of the population), it is still a substantial issue worthy of investigation, which is why this Special Issue focuses on congenital heart disease in both children and adults. Advances in the treatment of such malformations have led to increased life spans for this population. Consequently, today, most patients treated for congenital heart disease are adults. The purpose of this Special Issue is to deal with the latest developments in the care of the fetus, infants and children, and how these patients should be treated, as well as to describe the results of follow-ups and the potential special needs of adults with congenital heart disease
    Note: English
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  • 72
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036578422 , 9783036578439
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Medicine
    Abstract: Asthma is a prevalent chronic inflammatory disease of the airways with complex etiology and mechanistic pathways and variable clinical presentation. Such heterogeneity renders the search for targeted therapies difficult. Currently, the best-known disease phenotype with tailored biological treatment is eosinophilic asthma; however, even in some of these patients, anti-IL5 treatment is ineffective. Furthermore, about a quarter of patients, especially those with a severe phenotype, develop progressive and irreversible airway obstruction, leading to persistent symptoms despite optimized treatment. Therefore, new therapeutic approaches are still needed, particularly in severe asthma. The Special Issue presents asthma research focusing on modern personalized therapeutic approaches. Particular interest is directed to novel asthma biomarkers, including molecular and epigenetic ones, shining new light on pathogenesis, phenotyping, and customized therapy in various airway inflammatory patterns of the disease. In addition, research articles on airway epithelial cell dysfunction, airway remodeling, and the overlap between asthma and chronic obstructive pulmonary disease are welcomed. Stanislawa Bazan-Socha (Guest Editors)
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  • 73
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036574462 , 9783036574479
    Language: Undetermined
    Pages: 1 Online-Ressource (198 p.)
    Keywords: Medicine ; Oncology
    Abstract: In this Special Issue, we sought advanced knowledge in both basic and clinical research presented in original articles and comprehensive reviews highlighting the latest advances in MCC. Articles focus on but were not restricted to the molecular basis of the disease, translational investigations of biomarkers for prospective clinical applications, and innovative diagnostic and therapeutic approaches in MCC
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  • 74
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036578798 , 9783036578781
    Language: Undetermined
    Pages: 1 Online-Ressource (210 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: The present Special Issue will lead you to discover the association between cardiovascular and metabolic diseases, through update reviews and original articles exploring the pathophysiological mechanisms underpinning this association and describing the latest results in term of cardiovascular event prevention. An interesting scientific journey that reflects the recent advances in pharmacological treatments and interventional procedures
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  • 75
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575827 , 9783036575834
    Language: Undetermined
    Pages: 1 Online-Ressource (424 p.)
    Keywords: Medicine
    Abstract: Cannabis has a history of medical use dating back millennia; however, the use of cannabis for medicinal purposes fell out of favor in the middle of the last century. There is currently a renewed interest in the potential medicinal value of this plant, as well as individual compounds produced by Cannabis (as well as synthetic analogs). Currently, nearly 50 countries permit the medical use of cannabis, and over a dozen other countries have legalized cannabis-based products (CBD, Sativex, Dronabinol, etc.) for medical use. While there exists a plethora of anecdotal reports indicating that cannabis can treat a variety of diseases, there is a limited amount of strong, evidence-based scientific data to support these claims. This Special Edition of Biomedicines, “Therapeutic Potential for Cannabis and Cannabinoids”, was dedicated to providing evidence for the medicinal value of cannabis to treat human illness and disease. Topics included, but were not limited to, preclinical animal models examining the efficacy of cannabis and cannabinoid derivatives on pain, anxiety, cancer, and other diseases; and cell and molecular models of cannabinoid pharmacokinetics, drug–drug interactions, and disease treatment. These studies are of great importance not only for progressing the cannabis field, but also for validating the use of cannabis and cannabinoids as therapeutics
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  • 76
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    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579382 , 9783036579399
    Language: Undetermined
    Pages: 1 Online-Ressource (172 p.)
    Keywords: Medicine
    Abstract: Evidence has shown that botulinum toxin A has advantages in lower urinary tract dysfunctions (LUTDs), especially in interstitial cystitis, urethral sphincter dysfunction, and inflammatory bladder disorders which currently cannot be adequately treated with oral pharmacological medications. This Special Issue has collected original or review articles that focus on the novel applications of botulinum toxin A in LUTDs. The research has been updated and contains novel therapeutic applications of botulinum toxin for bladder or urethral dysfunctions. This Special Issue of Toxins provides current knowledge surrounding the status of botulinum toxin in functional urology and LUTDs
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  • 77
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579665 , 9783036579672
    Language: Undetermined
    Pages: 1 Online-Ressource (170 p.)
    Keywords: Medicine ; Medical toxicology
    Abstract: Over the last decades, interest in forensic toxicology has continually increased. Consequently, the discipline assumed a leading role, becoming one of the reference sciences for elucidating events of judicial importance. The need to reconcile analytical problems (e.g., relating to the qualitative/quantitative analysis of substances of abuse in complex biological matrices) with judicial requirements (i.e., providing data that can be used as documentary evidence in proceedings) makes the discipline unique among all "analytical" sciences. Thus, the availability of validated procedures, the constant monitoring of analytical performance through quality assurance protocols, the availability of certified “in matrix” standards, and the analytical problems underlying the analysis of new psychoactive substances in the blood and other biological fluids represent the challenges of modern forensic toxicology. The correct interpretation of analytical data, especially to elucidate the extent of impairment induced by a certain substance, and “old” issues related to the correct interpretation of post-mortem data (given the impossibility of translating the therapeutic ranges defined in vivo) represent further areas of research and debate among scientists. Finally, the possibility of interacting with other disciplines (such as proteomics and social sciences) allows for extending the concept of analytical data acquisition/interpretation beyond the classical limits of forensic toxicology (for example, considering the influence of gender when interpreting the effect of a substance)
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  • 78
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036580944 , 9783036580951
    Language: Undetermined
    Pages: 1 Online-Ressource (310 p.)
    Keywords: Medicine ; Pharmacology ; Research & information: general ; Chemistry ; Inorganic chemistry
    Abstract: Crystal engineering is a broad area of research that includes crystal habit modification, polymorphism, solid dispersions, and salt formation. This reprint covers state-of-the-art applications of crystal engineering and includes a combination of research and review articles, with special emphasis on novel drug delivery and targeting applications
    Note: English
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  • 79
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579948 , 9783036579955
    Language: Undetermined
    Pages: 1 Online-Ressource (154 p.)
    Keywords: Medicine
    Abstract: Comparative pathology, translational research, and clinical trials involving domestic animals have the ultimate goal of advancing our medical knowledge of both human and veterinary species. Companion, laboratory (from mouse to non-human primates), and wildlife animals play a pivotal role in our understanding of infectious diseases—particularly those with a zoonotic component. This reprint focuses on fundamental and applied research on the comparative pathology and immunohistochemistry of veterinary species. A total of 11 high-quality papers addressing different areas of pathology have been contributed by 62 authors from seven countries, comprising 9 research articles and 2 communications
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  • 80
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036580036 , 9783036580029
    Language: Undetermined
    Pages: 1 Online-Ressource (266 p.)
    Keywords: Medicine ; Pharmaceutical industries
    Abstract: Conventional ophthalmic formulations lack prolonged drug release effects and mucoadhesive properties, decreasing their residence time in the precorneal area and, therefore, in drug penetration across ocular tissues, presenting a low bioavailability with a consequent reduction in the therapeutic efficacy. These limitations are related to the physiological mechanisms of the eye, for example, the diluting effect of formulations exerted by the tear fluid, constant turnover of the tear fluid, blink reflex, limited capacity of the conjunctival sac, and drainage of formulations applied by gravity.To increase the residence time of formulations on the surface of ocular tissues and increase their ability to penetrate these tissues, different strategies can be used, namely, the use of viscosifying agents, mucoadhesive polymers, stimuli-responsive polymers, microparticles, and colloidal carriers (e.g., micelles, liposomes, nanosuspensions, nanoemulsions, polymeric, and lipid nanoparticles). This Special Issue combines the latest research and review works reporting the use of nanoparticles in ophthalmic formulations to increase their bioavailability and improve the therapeutic efficacy of ophthalmic formulations
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  • 81
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    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036580845 , 9783036580852
    Language: Undetermined
    Pages: 1 Online-Ressource (312 p.)
    Keywords: Medicine ; Clinical & internal medicine
    Abstract: Arthritis has a high prevalence globally and includes over 100 types; the most common types are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used for the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of a heart attack and other cardiovascular problems. Therefore, it is crucial that we continue to research the pathogenesis of arthritis and novel modes of therapy. This reprint summarizes and discusses the themes of 19 articles published in our Special Issue “Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0”. The reprint details important novel research discoveries that contribute to our current understanding of arthritis
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  • 82
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036578156 , 9783036578149
    Language: Undetermined
    Pages: 1 Online-Ressource (180 p.)
    Keywords: Medicine
    Abstract: This reprint provides a comprehensive overview and critically explores the recent trends in the zirconia additive manufacturing process or 3D printing and various surface treatments and their characterization for application in the dental and biomedical fields. It will be a valuable resource for the researchers to design or fabricate the implants according to clinical demands
    Note: English
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  • 83
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579306 , 9783036579313
    Language: Undetermined
    Pages: 1 Online-Ressource (228 p.)
    Keywords: Medicine ; Oncology
    Abstract: In Canada, survival from breast cancer has steadily increased since 1989, and breast cancer mortality has decreased by 48%. While 82% of women with breast cancer are diagnosed at stage 1 or 2, there are still 18% who present at a late stage and 25% who develop metastatic disease. Improved survival has been achieved through early diagnosis of breast cancer with screening, allowing for more effective and targeted treatments. This reprint summarizes the latest evidence on the early detection of breast cancer and highlights areas where this may be improved
    Note: English
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  • 84
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036575681 , 9783036575698
    Language: Undetermined
    Pages: 1 Online-Ressource (212 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents
    Note: English
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  • 85
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    Online Resource
    Montreal : McGill-Queen’s University Press (mqup)
    ISBN: 9780228017523 , 9780228017530 , 9780228017905 , 9780228018605
    Language: Undetermined
    Pages: 1 Online-Ressource (270 p.)
    Series Statement: Intoxicating Histories
    Parallel Title: Erscheint auch als Bhattacharya, Nandini Disparate remedies
    Keywords: Medicine
    Abstract: At present India is a leading producer, distributor, and consumer of generic medicines globally. Disparate Remedies traces the genealogy of this development and examines the public cultures of medicine in the country between 1870 and 1960. The book begins by discussing the expansion of medical consumerism in late nineteenth-century India when British-owned firms extended their sales into remote towns. As a result, laboratory-produced drugs competed with traditional remedies through side-by-side production of Western and Indian drugs by pharmaceutical companies. The emergent middle classes, the creation of a public sphere, and nationalist politics transformed the medical culture of modern India and generated conflict between Western and Indigenous medical systems and their practitioners. Nandini Bhattacharya demonstrates that these disparate therapies were sustained through the tropes of purity or adulteration, potency or lack of it, and epistemic heritage, even when their material configuration often differed little. Uniquely engaging with the cultures of both consumption and production in the country, Disparate Remedies follows the evolution of medicine in colonial India as it confronted Indian modernity and changing public attitudes surrounding health and drugs
    Note: English
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  • 86
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579597 , 9783036579580
    Language: Undetermined
    Pages: 1 Online-Ressource (168 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Advancements in medical imaging modalities have resulted in increasing the importance and demand of pediatric radiology. This reprint showcases various examples of advanced research in pediatric radiology and nuclear medicine. These include the use of medical imaging modalities such as computed tomography, general radiography, magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography, and ultrasound for diagnosis, as well as the performance of artificial intelligence (AI) in computer-aided detection and diagnosis in the pediatric population. The radiation dose issue of pediatric radiological examinations and emerging AI technology for dose reduction, as well as the use of three-dimensional printing based on medical images for pediatric surgical planning, healthcare professional education, and patient–clinician communication are also covered
    Note: English
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  • 87
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579351 , 9783036579344
    Language: Undetermined
    Pages: 1 Online-Ressource (138 p.)
    Keywords: Medicine
    Abstract: This collection of articles aims to promote the spread of a new way of resuscitating newborns in the delivery room: to perform exactly the same neonatal resuscitation procedures in a different landscape, that is, at mother's side with an intact cord
    Note: English
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  • 88
    ISBN: 9783036578866 , 9783036578873
    Language: Undetermined
    Pages: 1 Online-Ressource (196 p.)
    Keywords: Medicine ; Pharmacology
    Abstract: Humans have eaten nuts for thousands of years, yet their consumption was discouraged just a few decades ago due to their high-fat content. This perspective began to change in the early 1990s due to seminal publications from the Adventist Health Study, which showed that nut consumption significantly improved heart health-related outcomes. Many randomized clinical trials, epidemiological studies, and in vitro/in vivo mechanistic studies have since explored the role of eating nuts and its relation to health. Similarly, dried fruits have been scrutinized due to their concentrated sugar content despite their non-sodium micronutrient and fiber density. Due to accumulating evidence on nut and dried fruit intake and health outcomes, an international scientific meeting was organized for leading experts to examine and recapitulate in detail what is well known and established and what avenues of knowledge are still lacking in nut and dried fruit research. These findings highlight the beneficial health potentials of nuts for researchers, health professionals, other stakeholders, and the public while simultaneously pinpointing areas for further investigation to continue informing and guiding health practices and policies
    Note: English
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  • 89
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036580203 , 9783036580210
    Language: Undetermined
    Pages: 1 Online-Ressource (140 p.)
    Keywords: Medicine
    Abstract: This reprint focuses on personalized medicine in ophthalmic diseases, their challenges and opportunities, which often involves methods to achieve personalized diagnosis and treatment of ophthalmic diseases. Personalized medicine is a broadly used term to encompass approaches used to tailor healthcare to the needs of individual patients. It has been early adopted in ophthalmology and is mainly achieved through disease stratification and individualization. Therefore, diagnostic techniques that can realize comprehensive individual assessment are very important. Previous studies have put forward techniques such as next-generation sequencing and translational research. Gene therapy-based treatment trials have been presented for ophthalmic diseases such as retinitis pigmentosa and age-related macular degeneration. Recently, with the rapid development of artificial intelligence and interdisciplinary collaboration, concepts such as machine learning and wearable devices have been frequently discussed in ophthalmic research. There might be new promising methods to realize personalized ophthalmology
    Note: English
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  • 90
    Online Resource
    Online Resource
    Basel : MDPI - Multidisciplinary Digital Publishing Institute
    ISBN: 9783036579276 , 9783036579269
    Language: Undetermined
    Pages: 1 Online-Ressource (208 p.)
    Keywords: Medicine ; Oncology
    Abstract: Personalized medicine plays an important role in cancer prevention. To date, it is clear that many cancers are molecularly distinct subtypes, and different therapeutic approaches would be required for each. Indeed, the identification of cancer susceptibility genes permits identifying patients “at risk” of developing neoplasia and supports modifying individual risk behaviors or the choice of preventive therapy. Additionally, the efficacy of various targeted therapies in different cancer subtypes suggests that treatment choices in the near future will be more and more centered on molecular signatures. Data from preclinical, clinical, and observational studies have revealed the ability to prevent cancer development for compounds with different indications than cancer. The concept of drug repurposing permits combinations that can target several critical pathways of a specific disease, decreasing the risk of resistance observed when using single-agent targeted therapy.This open-access Special Issue brings together original research and review articles on molecular oncology with attention to the early detection and prevention of cancer. It highlights new findings, methods, and technical advances in molecular cancer research. The main feature of this Special Issue is to provide an open-source sharing of significant works in the field of molecular oncology that can increase our understanding of cancer development, which may lead to the discovery of new molecular diagnostic technologies and targeted therapeutics
    Note: English
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  • 91
    ISBN: 9782722606197
    Language: Undetermined
    Pages: 1 Online-Ressource
    Series Statement: Leçons inaugurales
    Keywords: Illness & addiction: social aspects ; Social discrimination & inequality ; Medicine
    Abstract: There is, on the one hand, life that flows from a beginning to an end, and, on the other hand, life that constitutes human singularity because it can be recounted. We may term them “biological life” and “biographical life”. Life expectancy measures the length of the former; a life story relates the richness of the latter. Only by acknowledging both can the inequality of lives be comprehended. They should be conceived of as being both distinct and connected: distinct, because the paradox of French women shows that a long life is no guarantee of a good life; connected, because the experience of African-American men stands as a reminder that a devalued life is a damaged life. This also raises the question of refugees and migrants
    Note: English
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  • 92
    ISBN: 9783031429446
    Language: English
    Pages: 1 Online-Ressource(XV, 650 p. 1 illus.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Medical laws and legislation. ; Medicine ; Biology ; Information technology ; Mass media ; Data protection.
    Abstract: Introduction -- Medical research and data protection in Europe. The emergence of general legal principles -- Part I Syllabus of the burning questions -- Anonymisation (Part I) ‘What is the state-of-the-art of anonymisation in data-driven health research and its role in the “European Health Data Space Regulation”?’ -- Anonymisation - The trap for biobanking (Part II) ‘Why the anonymisation could be a trap for the biobanking activity? Can there really be anonymisation in the research biobanks?’ -- Applying national law in cross-border research activity ‘Which national law should be applied in cross-border research activity in the local implementation of GDPR?’ -- Archived tissue ‘What is the potential use for research under GDPR for archived tissue specimens obtained in a diagnostic or therapeutic pattern?’ -- Blockchain and dynamic consent ‘Can the blockchain realise proper support for dynamic consent?’ -- Brexit effects ‘What are the “Brexit effects” on the exchange of data and biological samples with the UK?’ -- Broad consent ‘Do patients have to be informed about the concrete research projects for which their data and biosamples are to be used? Is so-called broad consent adequate?’ -- Cloud ‘How is it possible to exchange research and personal data using the cloud without being a danger to patients?’ -- Consent requirements ‘What are the terms and conditions of informed consent?’ -- Consent and assent by children ‘Management of assent and consent by children. What should be done when they reach the appropriate age: Obligations and recommendations?’ -- Consent & Technology ‘Is dynamic consent the solution or can an interactive website solve the problem of consent?’ -- Consent from children and vulnerable people ‘What protection is provided to people who are not able to give consent or are restricted in their ability to give consent, for example, children or people with disabilities?’ -- Consent withdrawal ‘What is the procedure if consent will later be withdrawn?’ -- Covid-19 ‘Are the rules of the GDPR on scientific research - if correctly applied - able to guarantee personal health data in the context of Covid-19 research activities?’ -- Dynamic consent ‘According to sentence three of recital 33, persons whose data are to be stored for future research projects should be given the opportunity to provide their consent to only certain areas of research or parts of research projects to the extent permitted by the purpose pursued. How can this be realised?’ -- Ethics committees ‘To what extent are ethics committees relevant for the activities of the biobank?’ -- Ethic & Biobanks ‘What are the steps needed to implement bioethical issues in a population-based and disease-based biobank?’ -- Ethical principles and legal provisions ‘What ethical principles apply to biobanking activities?’ -- EU legislation and health data protection ‘For the processing of medical personal data in biobanking activities, is the GDPR the sole reference legislation in the EU?’ -- Forensic databases (Part I) ‘Forensic use of research biobanks: How does the GDPR regulate the issue?’ -- Forensic databases (Part II) ‘How does EU law address issues concerning access for forensic purposes to research biobanks?’ -- Future research ‘How to deal with the problem that future research may often not be able to be defined in narrow and specific terms, as it depends on the current state of research?’ -- Genetic data ‘What are the ethical–legal consequences entailed in the exceptional nature of genetic information?’ -- Granularity ‘When processing personal data and biological material in research activities, is it possible to derogate from the general rules and, in particular, from the rule of granularity of consent?’ -- Imaging biobank ‘What are the areas of the GDPR bearing on an image biobank?’ -- Industry perspective ‘Contracting in the light of the GDPR: What are the key considerations for transfers of biosamples and data from an industry perspective?’ -- Joint controller agreement ‘What is the function of the joint controller agreement in sharing personal data with a large research consortium or biobank infrastructures?’ -- Legitimate interests ‘Are legitimate interests lawful grounds for processing retrospective health data and tumour tissue?’ -- Ownership of human biological material ‘To whom does the “ownership” of the human body and its parts belong? Who has the right to dispose of it and for what purpose?’ -- Paediatric biobanks (general overview) ‘How to tackle the protection of personal data and other ethical issues in a paediatric biobank? -- Public Interest Who decides on the existence of a public interest?’ -- Rare diseases and data protection (Part I) ‘How to enable research on rare diseases while protecting personal data?’ -- Rare diseases and legal, ethical, technical and societal needs (Part II) ‘Why are biobanks and research networks able to support data protection issues in rare disease research?’ -- Rare paediatric diseases ‘Does the GDPR support dynamic consent/assent strategies for rare paediatric diseases?’ -- Residual material ‘What applies to the processing of residual material with its associated data? Is explicit consent required for this?’ -- Retention time - conservation of personal data (Part I) ‘How long can personal data be stored in a biobank?’ -- Retention time - conservation of tissues (Part II) ‘How long can tissues be stored in a biobank?’ -- Retrospective research ‘Is the use of broad consent for retrospective research on data and tissue possible in the framework of GDPR?’ -- Scientific research and the biomedical sector. Requirements and methods for planning and managing a “data protection by design” project. ‘How can a scientific research project be planned and managed to comply “by design” with GDPR?’ -- Secondary use (Part I) ‘What does secondary use mean for research using tissue specimens obtained in a diagnostic or therapeutic setting, in the light of the GDPR?’ -- Secondary use and dual use of biomaterial samples (Part II) ‘Does broad consent include the reuse and dual use of biomaterial samples and their associated personal data?’ -- Transfer of the personal data for research purposes towards non-EU countries ‘How is it possible to transfer personal data for research purposes to non-EU countries? -- Users ‘Who are the users in the context of biobanks? What are the factors to consider when dealing with the human component?’ -- Part II Biobanking legal and ethical requirements across Europe: National reports (in alphabetic order) -- Instead of a preface Towards regulation for the European health data research: A comparative analysis -- National report: Austria -- National report: Belgium -- National report: Bulgaria -- National report: Croatia -- National report: Cyprus -- National report: Czech Republic -- National report: Denmark -- National report: Estonia -- National report: Finland -- National report: France -- National report: Germany -- National report: Greece -- National report: Hungary -- National report: Ireland -- National report: Italy -- National report: Latvia -- National report: Lithuania -- National report: Luxemburg -- National report: Malta -- National report: Netherlands -- National report: Poland -- National report: Portugal -- National report: Romania -- National report: Slovakia -- National report: Slovenia -- National report: Spain -- National report: Sweden -- National report: United Kingdom -- Conclusion.
    Abstract: The book deals with the effective operation of the rules related to biomedical research and pays attention to the activities of the national legislatures of the 27 Member States in the field of scientific research. This multilevel system has an impact on biobanking activity. The book answers questions realized by operators on the main biobanks around the EU in the field of GDPR. The authors and editors used the questions born from brainstorming among members of the Association European, Middle East & Africa for Biopreservation and Biobanking (ESBB) to offer to the operators in biobanking activity and researchers quickly answer to their daily questions, but with authors highest quality. Further the book provides a comprehensive review of the rapidly expanding field of biobanking. It provides researchers and scholars working on biobanking and bio-sharing and more in general in the university hospitals and clinical trial consortiums, and companies, biomedical researchers, but also jurists and the professionals (in particular judges, lawyers, officers) an instrument rigorous but easy to use of the GDPR in the case of biobanking activities. The book identifies a methodological path to tackle the legal or ethical problem on a specific scientific-technological to verify existing solutions and give ideas for future applications. The importance of the legal solution influences the implementation of the development of the biobanking activity service itself.
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  • 93
    ISBN: 9783031236587
    Language: English
    Pages: 1 Online-Ressource(XIV, 144 p. 1 illus.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Medicine—History. ; History, Modern. ; Medical policy. ; World history. ; Social policy. ; Medicine
    Abstract: 1. Introduction - Before e-cigarettes: The Pre-history of Public Health, Tobacco and Nicotine in the United Kingdom, Australia and the United States; Virginia Berridge, Amy Fairchild, Kylie Morphett, Coral Gartner, Wayne Hall and Ronald Bayer -- 2. Outlier or Pioneer? The development of policy on E-cigarettes in England; Virginia Berridge -- 3. The development of e-cigarette policy in Australia: the policy, how it came about and how it is justified; Kylie Morphett, Wayne Hall and Coral Gartner -- 4. E-Cigarettes and the Burdens of History: Children, Bystanders, and the American War on Nicotine; Ronald Bayer and Amy Lauren Fairchild -- 5. Conclusion: Why did the UK, US, and Australia have different e-cigarette policies?; Virginia Berridge, Amy Fairchild, Kylie Morphett, Coral Gartner, Wayne Hall and Ronald Bayer.
    Abstract: This open access book offers the first in-depth study of the history and current debates surrounding electronic cigarettes comparing the UK, US and Australia. Since their introduction, e-cigarettes have been the subject of much public, media and regulatory attention, with discussion centring on whether these devices encourage or discourage smoking. This study delves into the history of policymaking and institutions in three countries which have taken different approaches to the regulation of e-cigarettes. In the UK, the tradition of harm reduction through nicotine has helped form a response which has endorsed e-cigarettes, though not without considerable controversy. In contrast, the US has a cessation-only anti-tobacco agenda, and Australia has effectively banned e-cigarettes. This book argues that each country frames the long-term use of nicotine differently and prioritises the health of different groups within the population of smokers or non-smokers, set against a broad backdrop of national responses to addiction. By taking this comparative approach, the authors explore the relationship between history, evidence and policy in public health more widely. Virginia Berridge is Professor of History and Health Policy at the Centre for History in Public Health, London School of Hygiene and Tropical Medicine, UK. Ronald Bayer is Professor and Co-Chair at the Center for the History and Ethics of Public Health at Columbia University’s Mailman School of Public Health, New York, USA. Amy L. Fairchild is Dean of the College of Public Health and Professor of Health Services Management and Policy, Ohio State University, USA. Wayne Hall is an Emeritus Professor at the Centre for Youth Substance Use Research at the University of Queensland, Australia. .
    Note: Open Access
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  • 94
    Online Resource
    Online Resource
    Cham : Springer Nature Switzerland | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031437779
    Language: English
    Pages: 1 Online-Ressource(XVIII, 193 p. 11 illus.)
    Edition: 1st ed. 2023.
    Series Statement: Palgrave Studies in Oral History
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Oral history. ; United States ; Medicine ; Public health.
    Abstract: Chapter 1 Introduction: The Situation and the Story -- Section I: Why is midwifery essential for a robust maternal health care system? -- Chapter 2 Rosie Hernandez: Becoming a guardian of births for other women -- Chapter 3 Jillia Edris: Speaking up for midwifery care -- Chapter 4 Marylyn Garcia: Relying on midwifery care through birth and death -- Section II: Deconstructing racism -- Chapter 5 Lizette Aguilar: Deepening connection to her Latina heritage -- Chapter 6 Zakiyyah Madyun: Finding her voice in policy -- Chapter 7 Dana Keys: Understanding the racialization of the US health care system -- Section III: Transforming legacy -- Chapter 8 Elizabeth Miron: Breaking the legacy of maternal mortality -- Chapter 9 Nana Oumou Toure: Connecting global to local -- Chapter 10 Grace Zambrano: Building new traditions for her family -- Section IV: Empowerment -- Chapter 11 Tyice Tucker: Discovering strength and sense of self through her births -- Chapter 12 Fatoumata: Becoming a leader against female cutting -- Chapter 13 Nkenge Mollineaux: Facing tragedy while building her family -- Chapter 14 Conclusion: Time to Push - A Call for Better Birthing and Safe Motherhood in America.
    Abstract: Women came through the doors at a community-based birthing center in the South Bronx seeking prenatal care. They had heard about the center from a neighbor, a parents' group at their children’s school, or the local mosque or church. What they found when they arrived was a brightly-colored waiting area that resembled a living room, children immersed in games in a corner, and staff that reflected the mosaic of cultures living in the surrounding apartments. They also met midwives who asked about their lives, their children, their families and traditions. If pregnancies developed complications, back-up obstetricians were there to give higher levels of care, with the women returning to the midwifery center afterwards. The results were healthy mothers and healthy babies. For over twenty years the center became a haven for women’s health care and a national exemplar. It is a tragic and unjust paradox that the United States, the highest income country in the world and the country with the largest budget for perinatal care, has rising rates of maternal mortality that disproportionately affect women of color. Yet an inner-city maternity center with midwifery care found solutions to the challenge of making birth safe for low-income populations, especially women of color. This oral history presents the stories of twelve women who participated in this care. As they tell it, the experience changed their lives and their understanding of what safe, quality maternal care can achieve. Jennifer Dohrn examines the systems that perpetuate disparities in care, from global to local, and describes essential components needed for change, using oral histories as evidence for the way forward towards maternal health as a human right. Jennifer Dohrn is a Professor and Assistant Dean of the Office of Global Initiatives and its PAHO/WHO Collaborating Center for Advanced Practice Nursing at Columbia University School of Nursing, USA. As Director of Midwifery Services, with the leadership of Dr. Ruth Lubic she initiated the first freestanding maternity center in an inner city in the United States in the Bronx, New York, which became a model for community-based midwifery care.
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  • 95
    Online Resource
    Online Resource
    Singapore : Springer Nature Singapore | Singapore : Imprint: Springer
    ISBN: 9789819986354
    Language: English
    Pages: 1 Online-Ressource(XXXII, 219 p. 114 illus., 31 illus. in color.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Medicine ; China ; Pharmacy. ; Pharmaceutical chemistry. ; Imperialism.
    Abstract: The Beginnings of Western Influence on Chinese Medicine, 200 BCE – 1800 CE -- Trade Wars and the Emergence of Western Pharmacy -- Union Medical College and the “Cradle of Modern Medicine” -- The Rise of Western Chemists -- “Opium Cures”, Proprietary Medicine and Soda Water -- Pharmaceutical Education and Manpower Development.
    Abstract: This book represents an important contribution to the field as it is the first to provide a detailed account of the interaction between Chinese and western medicine from a pharmacy perspective over a period of two millennia with an emphasis on the modern period from 1800-1949. None of the existing historiography on the relationship between TCM and western medicine has so far explored pharmaceutical aspects in detail. This book therefore fills an important gap in the literature and is likely to become a key resource for further study. It will be of interest to a wide audience, including pharmaceutical, imperial, and business historians, and should be essential reading for pharmacy students. But it will also be of interest to a general readership curious about the history of pharmacy in China and of western influences on Chinese medicine. Stuart Anderson, BSc, MA, PhD, FRPharmS Editor-in-Chef, Pharmaceutical Historian, Emeritus Professor of Pharmacy History, London School of Hygiene & Tropical Medicine Readers of this book, to Chiu’s credit, will be exposed to the nuanced cultural, medico-scientific, and business interactions that shaped Western pharmacy in China. Chiu puts a spotlight on the various materials, techniques, and processes of drug formulation and mass manufacture – and he rightly illustrates how pharmacy was substantiated as big business and mass manufacture. In analyses that incorporate materia medica and so-called dangerous drugs, such as opium, Chiu also articulates the complicated entangled histories of the movement, circulation, and translation of both pharmacy knowledge and goods. Yet, he appropriately acknowledges and evaluates non-Western epistemologies and practices that intermingled with Western ideas to create a novel type of pharmacy and pharmaceutical industry in China. Lucas Richert, PhD Professor & George Urdang Chair in Pharmacy History, UW-Madison Executive Director, American Institute of the History of Pharmacy Patrick Chiu's book, A History of Western Pharmacy in China, effectively presents an unbiased perspective when discussing the contributions of expatriate pharmacy academics towards the development of China's pharmaceutical profession and the modern drug industry in the first half of the twentieth century. Chiu's impartial approach and well-researched content make it a recommended resource for understanding the historical development of pharmacy in China. Kazushige Morimoto Ph.D. D.Min, Education System - Qualified Pharmacist, President, The Japanese Society for the History of Pharmacy .
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  • 96
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031224966
    Language: English
    Pages: 1 Online-Ressource(VIII, 174 p. 19 illus., 15 illus. in color.)
    Edition: 1st ed. 2023.
    Series Statement: Mental Health in Historical Perspective
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Italy—History. ; Medicine—History. ; Economic history. ; Social history. ; Sociology. ; Nutrition. ; Food. ; Medicine ; Italy
    Abstract: 1. Rough Skin: An Introduction -- Part I. Pellagra -- 2. Medical Reactions to a New Disease in the Eighteenth Century -- 3. The Aetiological Turn in the Nineteenth Century -- 4.The Bacteriological Divide: Pellagra in Italy and the United States during the Twentieth Century -- Interlude: Patient Voices -- Part II. Pellagrous Insanity -- 5. Institutionalising Pellagrous Insanity -- 6. Understanding Insanity: Pellagra and General Paralysis of the Insane in Italy and the United Kingdom -- 7. Experiencing the Asylum -- 8. Conclusion: Leaving the Asylum.
    Abstract: This open access book explores the history of pellagra, a vitamin deficiency disease brought about by a shift in agriculture to maize, which ravaged Italy from the 1760s. With a focus on the insanity that was caused by the disease, the authors examine how thousands of patients were treated in Italian psychiatric asylums, shedding light on the sufferer’s point of view. Setting pellagrous insanity in a wider context of man-made or societal (anthropogenic) disease, where poverty, diet and disease meet, the book contributes to the history of medicine and science, the history of psychiatry, economic and social history, agrarian history, and food and nutrition history. Additionally, the authors aim to transnationalise Italian history by making comparisons with related issues, such as tertiary syphilis in the UK. Drawing from a wide range of printed and archival sources, including the writings of Italian medical investigators and patient records, the book examines how medical and scientific research was carried out during the long nineteenth century and the uncertainties that this engendered, in terms of classification, explanation, diagnosis and treatment. Offering a unique perspective on an endemic illness which came to be known as the disease of the four ds -- dermatitis, diarrhea, dementia and death—this book provides an engaging account of one of the most perplexing causes of mental illness.
    Note: Open Access
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  • 97
    Online Resource
    Online Resource
    Cham : Springer Nature Switzerland | Cham : Imprint: Springer
    ISBN: 9783031292392
    Language: English
    Pages: 1 Online-Ressource(IX, 296 p. 1 illus.)
    Edition: 1st ed. 2023.
    Series Statement: Philosophy and Medicine 133
    Parallel Title: Erscheint auch als Incentives and Disincentives in Organ Donation
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    RVK:
    Keywords: Medicine—Philosophy. ; Ethics. ; Medicine
    Abstract: Part 1. Introduction -- Chapter 1. Towards a New Model of Incentives for Organ Donation (Ruiping Fan) -- Part 2. Beijing papers -- Chapter 2. The Background of Organ Donation in Mainland China (Guangkuan Xie) -- Chapter 3. Mixed Incentives, Different Voices: A Qualitative Study of Organ Donation Incentive Policies in Two Big Chinese Cities (Jian Tang) -- Chapter 4. Organ Donation Incentives in Mainland China: Ethical Commentaries and Reform Recommendations (Jian Tang) -- Part 3. Chicago papers -- Chapter 5. The Concepts and Development of Organ Donation Policy in the United States (Wan-Zi Lu) -- Chapter 6. Interviews in Chicago (Wan-Zi Lu) -- Chapter 7. Ethical Considerations about Three Incentive Models based on Research in Chicago (Wan-Zi Lu) -- Part 4. Tehran papers -- Chapter 8. The Kidney Transplantation Program in Iran (Mitra Mahdavi-Mazdeh) -- Chapter 9. Interview Findings of the Organ Donation in Iran (Mitra Mahdavi-Mazdeh) -- Chapter 10. A Comment on the Barriers and Incentives of Organ Donation in Iran (Mitra Mahdavi-Mazdeh) -- Part 5. Hong Kong papers -- Chapter 11. Organ Donation: The Hong Kong Context (Ho Mun Chan) -- Chapter 12. Incentives for Organ Donation in Hong Kong: In-depth Interviews (T-fai Yeung) -- Chapter 13. Incentives for Organ Donation in Hong Kong: A Survey (Yang Zheng) -- Chapter 14. Organ Donation, Comprehensively Good Incentives, and the Family: A Comment on Hong Kong’s Interview Findings and Survey Results (Ruiping Fan) -- Part 6. Implications for Hong Kong and other societies: Towards a New Model -- Chapter 15. Organ Donation Incentives: A Multicultural Comparison (Lisa M. Rasmussen) -- Chapter 16. Organ Donation Incentives: Implications for Hong Kong and Beyond (Chunyan Ding).
    Abstract: This book provides the first systematic study on three types of incentives for organ donation. It covers extensive research conducted in four culturally different societies: Hong Kong, mainland China, Iran and the United States, and shows on the basis of the research that a new model of incentives can be constructed to enhance organ donation in contemporary societies. The book focuses on three types of incentives: honorary incentives, commonly adopted in the United States and other Western countries by offering things such as a thank-you card and a memorial park for donors to encourage donations motivated by pure altruism; compensationalist incentives, adopted in the Islamic Republic of Iran to encourage donation by providing monetary compensation to unrelated living donors for appreciating their altruistic contribution of donation; and familist incentives, implemented in Israel and mainland China to provide priority to organ transplantation to donors and/or their family members. The book demonstrates that a new model of incentives must go beyond offering only one type of incentives and should rather include different types of incentives that are practically effective, politically legitimate and ethically justifiable for particular societies. This implies that suitable incentive measures may vary from society to society to optimize organ donation. This book provides a clear reference for both the scholars and practitioners in the field of organ transplantation, as well as for general readers interested in bioethics and health care policy.
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  • 98
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Springer
    ISBN: 9783031301186
    Language: English
    Pages: 1 Online-Ressource (XXII, 327 pages) , Illustrationen
    Parallel Title: Erscheint auch als Hollerbach, Teresa Juliane Sanctorius Sanctorius and the origins of health measurement
    Keywords: Science—History. ; Science—Philosophy. ; Medicine—History. ; Technology. ; History. ; Knowledge, Theory of. ; Science ; Science ; Medicine
    Abstract: Acknowledgements -- Preface (Dr. Matteo Valleriani) -- Introduction -- List of Figures -- Abbreviations and Short Titles -- Chapter 1. Sanctorius Sanctorius—Between Koper and Venice -- Chapter 2. Sanctorius’s Galenism -- Chapter 3. Sanctorius’s Work in its Practical Context -- Chapter 4. Quantification in Galenic Medicine -- Chapter 5. Quantification and Certainty -- Chapter 6. The Measuring Instruments -- Chapter 7. Sanctorius Revisited -- List of Appendices.
    Abstract: This open access book offers new insights into the Venetian physician Sanctorius Sanctorius (1561–1636) and into the origins of quantification in medicine. At the turn of the seventeenth century, Sanctorius developed instruments to measure and quantify physiological change. As trivial as the quantitative assessment of health issues might seem to us today – in times of fitness trackers and smart watches – it was highly innovative at that time. With his instruments, Sanctorius introduced quantitative research into the field of physiology. Historical accounts of Sanctorius and his work tend to tell the story of a genius who, almost out of the blue, invented a new medical science, based on measurement and quantification, that profoundly influenced modernity. Abandoning the “genius narrative,” this book examines Sanctorius and his work in the broader perspective of processes of knowledge transformation in early modern medicine. It is the first systematic study to include the entire range of the physician’s intellectual and practical activities. Adopting a material culture perspective, the research draws on the contemporary reconstruction of Sanctorius’s most famous instrument: the Sanctorian weighing chair. And here it departs from past studies that focus mainly on Sanctorius’s thinking rather than on his making and doing. The book also re-evaluates Sanctorius’s role in the wider process of the early transformation of medical culture in the early modern period, a process that ultimately led to the abandonment of Galenic medicine and to the introduction of a new medical science, based on the use of quantification and measurement in medical research. The book is therefore an important contribution to the history of medicine and historical epistemology aimed at historians of science and philosophy.
    Note: Open Access
    URL: Cover
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  • 99
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783030908355
    Language: English
    Pages: 1 Online-Ressource(XVII, 283 p.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: Latin America—History. ; Medicine—History. ; Nursing. ; Social history. ; Labor. ; History. ; Latin America ; Medicine
    Abstract: 1. Background: The Struggle for Public Health and Equality -- 2. Nursing in Times of Socialism (1970–1973) -- 3. Nursing Under the Civilian-Military Cooperation (1973–1979) -- 4. Nursing in Times of State Reforms (1980–1982) -- 5. Nursing in Times of Transition and Distinction (1982–1990).
    Abstract: "A much-needed study that reveals the fundamental significance of the nursing profession in the history of public health and traces the important contributions nurses made to the creation of a functioning healthcare system. It explores vital questions of gender, medical practice, and power." —Jadwiga Pieper-Mooney, University of Arizona, USA "The authors convincingly demonstrate the links between nurses, past and present. This is an essential read for both studying processes of yesteryear and reviewing health policy of today." —Karina Ramacciotti, National University of Quilmes, Argentina This book offers the first in-depth account of healthcare policy in Chile across the twentieth century. It charts how nursing and nurses intersected with the political context of healthcare, with a focus on the country’s transition across welfare systems. Drawing on extensive archival research and interviews with nurses and governmental representatives, this book explores how the nursing profession implemented and challenged reform, while policies had an impact on nurses. It analyses nurses’ employment and mobility, and their lobbying through the press and through unions. The authors demonstrate that while Chilean health policy was influenced by US cultural politics, reform depended on the flexibility and willingness of nurses to carry through reforms. By examining the participation of the largest female professional group, the book offers new insights into the privatization of society on the pinnacle of industrial development and seeks to contribute to contemporary debates on Chile’s welfare system. It is a vital read for scholars researching the history of public health. Markus Thulin is based at the Brauweiler Memorial Site of the Rhineland Regional Council, Germany. He has been both a researcher of Latin American history at the University of Cologne and a history lecturer, with his interests revolving around women’s history, history of healthcare and history teaching. Ricardo A. Ayala is a sociologist with a background in history, healthcare and political science. He is a professor of ethics at Universidad de las Américas, Chile, and a research affiliate at Ghent University, Belgium.
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  • 100
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Palgrave Macmillan
    ISBN: 9783031217142
    Language: English
    Pages: 1 Online-Ressource(XIV, 353 p. 10 illus., 4 illus. in color.)
    Edition: 1st ed. 2023.
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Parallel Title: Erscheint auch als
    Keywords: United States—History. ; Medicine—History. ; Law—History. ; Social history. ; World politics. ; Race. ; United States ; Law ; Medicine
    Abstract: Chapter 1.Introduction -- Chapter 2.“Friendless and Homeless:” The Gold Rush to 1870 -- Chapter 3. “A Sin and a Shame:” Regional Institutional Development in the Late 19th Century -- Chapter 4. “Helpless and Delinquent”: The Los Angeles Psychopathic Association -- Chapter 5. “The Thankless Task:” Parole, Eugenics; and the Institutionalization of the Addicted -- Chapter 6. “Their Responsibility:” From the Great Depression to the Birth of the Community Clinic -- Chapter 7. “To Promote Mental Health:” The Bureaucracy of Disability at Midcentury -- Chapter 8. “Whistling in the Dark:” California’s Politics of Disability Transformed -- Chapter 9. California after the Lanterman-Petris-Short Act -- Conclusion.
    Abstract: This book explores the political, legal, medical, and social battles that led to the widespread institutionalization of Californians with disabilities from the gold rush to the 1970s. By the early twentieth century, most American states had specialized facilities dedicated to both the care and the control of individuals with disabilities. Institutions reflect the lived historical experience of many Americans with disabilities in this era. Yet we know relatively little about how such state institutions fit into specific regional, state, or local contexts west of the Mississippi River; how those contexts shaped how institutions evolved over time; or how regional institutions fit into the USA’s contentious history of care and control of Americans with mental and developmental disabilities. This book examines how medical, social, and political arguments that individuals with disabilities needed to be institutionalized became enshrined in state law in California through the creation of a “bureaucracy of disability.” Using Los Angeles County as a case study, the book also considers how the friction between state and county policy in turn influenced the treatment of individuals within such facilities. Furthermore, the book tracks how the mission and methods of such institutions evolved over time, culminating in the 1960s with the birth of the disability rights movement and the complete rewriting of California’s laws on the treatment and rights of Californians with disabilities. This book is a must-read for those interested in the history of California and the American West and for anyone interested in how the intersections of disability, politics, and activism shaped our historical understanding of life for Americans with disabilities. Eileen V. Wallis is Professor of History at California Polytechnic State University, Pomona, in Pomona, California, USA. Her research focus is the late nineteenth- and early twentieth-century American West, with a focus on California. She is particularly interested in the intersections of race, gender, disability, and class, and the ways in which those variables interacted with structures of power during the Progressive era. .
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